Radiobiology I Direct and Indirect action • The biologic effects of radiation result principally from damage to DNA which is the critical target • The atoms of the target…
1. 4 Rs of Radiobiology By Dr. Deepa Gautam 1st yr resident, Radiotherapy 1 2. • The four R’s of radiobiology are the concepts to explain the rationale behind the fractionation…
1. MECHANISMS OF DNA REPAIR Dr Radhouane GOUIAA Policlinique CNSS 3018 Sfax – TUNISIA 5th ADVANCED POSTGRADUATE COURSE 2nd Training Session June 2003 2. DNA DAMAGE 1- Tautomerisation:…
RADIATION HAZARDS AND SAFETY RADIATION HAZARDS AND SAFETY 1 RADIATION HAZARDS The radiation exposure usually results from diagnostic as well as therapeutic radiation devices.…
Slide 1The Radiobiology of Radiation Therapy Slide 2 Type of Injuries Nuclear DNA is major target Nuclear DNA is major target Cellular membrane damage – minor Cellular…
Slide 1Bio3124 Lecture 8 Slide 2 Total cell DNA = genome (chromosome & extra-chromosomal) Human genome = 4 billion bp – 1000x as large as E. coli genome – 90% junk…
Slide 1 Sorting Cancer Karyotypes by Elementary Operations Michal Ozery-Flato and Ron Shamir School of Computer Science, Tel Aviv University Slide 2 Outline Introduction…
Slide 1 By: Brittany Duncan Mentors: Janet Sinsheimer PhD (UCLA) Mary Sehl M.D.(UCLA) DNA repair SNPs Associated with Breast Cancer Slide 2 What We Aim to Do To ultimately…
Slide 1 Transposition and transposable elements Slide 2 Transposable elements “mobile genetic elements” comprise 45% of human chromosomal DNA “middle repetitive DNA”…