1. Drug Design(DOCKING)By: JAIDEEP SARKAR ARE HDG BF CP 2. Drug DesignHigh Throughput Screening→104 ligands per day But: Hit Rate 10-6 per ligand 3. RATIONAL DRUG DESIGN…

Slide 1 Two Examples of Docking Algorithms With thanks to Maria Teresa Gil Lucientes Slide 2 Example: HIV-1 Protease Active Site (Aspartyl groups) Docking to find drug candidates…

Slide 1 Protein Docking and Interactions Modeling CS 374 Maria Teresa Gil Lucientes November 4, 2004 Slide 2 Overview of the lecture Introduction to molecular docking: Definition…

CZ5226: Advanced Bioinformatics Lecture 8: Molecular Modeling Method Prof. Chen Yu Zong Tel: 6874-6877 Email: [email protected] http://xin.cz3.nus.edu.sg Room 07-24, level…

CZ5226: Advanced Bioinformatics Lecture 8: Molecular Modeling Method Prof. Chen Yu Zong Tel: 6874-6877 Email: [email protected] http://xin.cz3.nus.edu.sg Room 07-24, level…

BL5203: Molecular Recognition & Interaction Lecture 5: Drug Design Methods Ligand-Protein Docking (Part I) Prof. Chen Yu Zong Tel: 6874-6877 Email: [email protected]…