1. Dr. VARUN GOEL MEDICAL ONCOLOGISTRAJIV GANDHI CANCER INSTITUTE, DELHI 2. • In the 1950s, simultaneous efforts by FrenchandItalianresearchersledto thedevelopment of Daunorubicin.•…
1. DNA Replication 2. DNA – DOUBLE HELICALSTRUCTURE WATSON and CRICK- Model 3. DNA – DOUBLE HELICALSTRUCTURE 4. Directionality of DNA Nucleotides in DNA backbone are…
Slide 1 DNA Topoisomerases maintain promoters in a state competent for transcriptional activation in Saccharomyces cerevisiae. 21 June 2013 Ph.D. student Jacob Fredsøe Laboratory…
Slide 1 Part 4. How Genomes Replicate and Evolve Slide 2 The primary function of a genome is to specify the biochemical signature of the cell in which it resides. In Part…
Slide 1 Model of DNA strand cleavage by topoisomerase I. Formation of the covalent bond involving tyrosine 723 is shown, as are other active site amino acids believed to…
Slide 1 Slide 2 Local unwinding during replication results in overwinding or supercoiling of surrounding regions DNA topology Lk = Tw + Wr From the field of topology: twist…
Slide 1 1 Chapter Overview ● RNA polymerases and sigma factors ● Transcription: DNA is converted to RNA ● The genetic code, ribosomes, and tRNAs ● Translation: RNA…
Slide 1 Review session for exam-II Lectures 6-9 Slide 2 DNA Replication Q1. An assay used to determine carcinogenic potential is the ____________ test. Slide 3 DNA Replication…