Clinical Pharmacokinetics (1) • A fundamental hypothesis of clinical pharmacokinetics is that a relationship exists between effects of a drug and concentration of the drug…

Slide 1Pitfalls in Prescribing for older people Christopher Patterson McMaster University, Hamilton, Ontario Canada Slide 2 Objectives Pharmacokinetic changes with age Pharmacodynamic…

1. Excretion KIDNEY GLOMERULAR FILTRATION: Clearance of the apparent volume of distribution by passive filtration. • Drug with MW < 5000 ------> it is completely…

1. Excretion KIDNEY GLOMERULAR FILTRATION: Clearance of the apparent volume of distribution by passive filtration. • Drug with MW < 5000 ------> it is completely…

Slide 1 CONCEPT OF CLEARANCE PRESENTATION BY RAVULAPALLI CHIRANJEEVI 1ST M.Pharmacy(Pharmaceutics) Vikas college of Pharmacy 1 Concept of clearance Renal Clearance Factors…