Cell cycle, CDKs and cancer: a changing paradigm Proliferação não programada Instabilidade genômica 13 CDKs e 25 ciclinas mas nem todas contam cdks 4, 6, 2 (interfase)…
BRCA1 Breast Cancer BRCA1 has many binding domains and thus involved with several complexes with distinct functions Steven A. Narod & William D. Foulkes, 2004 BRCA1 functions…