1. Breast Cancer Genetics and Clinical Trials Dr James Mackay Consultant Clinical Genetic Oncologist 2. Inherited genetic variation and treatment outcome Clinical Pharmaco-genetics…

1. Prevention of Breast Cancer Breast Diseases Fourth Edition, chapter 6 2. screening • reduce mortality but not the incidence • cost effective only among women for whom…

Slide 1  Inflammations ( Salpingitis )  almost always bacterial in origin.  Chlamydia, Mycoplasma, coliforms, (postpartum) strept. and staph. are now the major offenders.…

Slide 1 BRCA Genes Dallas Henson Slide 2 BReast CAncer Women have about a 1 in 7 chance of getting breast cancer in their lifetime. Most cancer is sporadic, about 5-10% of…

Slide 1 BRCA Mutations and Breast Cancer Ruth Phillips and Patty Ashby Slide 2 Breast Cancer Most common cancer in women Second cause of cancer death in women Rates in men???…

Tumor Suppressor Gene Involved in Breast and Ovarian Cancers www.ncbi.nlm.nih.gov/ SCIENCE96/gene.cgi?BRCA1 Summary Facts about Breast and Ovarian Cancer Discovery of BRCA1…

Microarray oligonucleotide microarrays [Hu6800 and Hu35KsubA GeneChips (Affymetrix, Santa Clara, CA)] containing a total of 16,063 probe sets representing 14,030 GenBank…