Slide 1 De-novo Assembly Day 4 Slide 2 The Challenge Given many (millions or billions) of reads, produce a linear (or perhaps circular) genome Issues: – Coverage – Errors…
CS 394C March 19, 2012 Tandy Warnow * DNA target sample SHEAR & SIZE End Reads / Mate Pairs 550bp 10,000bp Shotgun DNA Sequencing Not all sequencing technologies produce…
CS 394C Oct 16, 2013 Tandy Warnow * DNA target sample SHEAR & SIZE End Reads / Mate Pairs 550bp 10,000bp Shotgun DNA Sequencing Not all sequencing technologies produce…
De-novo Assembly De-novo Assembly Day 4 The Challenge Given many (millions or billions) of reads, produce a linear (or perhaps circular) genome Issues: Coverage Errors in…
CS 394C March 19, 2012 Tandy Warnow * DNA target sample SHEAR & SIZE End Reads / Mate Pairs 550bp 10,000bp Shotgun DNA Sequencing Not all sequencing technologies produce…