Slide 1 May 8 th, BIOSE108 Therapeutic approaches in AD: -Beta and gamma secretase inhibitors -Abeta immunotherapy -Tau -Ongoing treatments in AD Slide 2 - and -secretase…
The aspartyl protease BACE b-Amyloid cleaving enzyme BACE is expressed mostly in the brain Vassar et al., 1999 Vassar et al., 1999 In the cell, BACE localizes to Golgi apparatus…
May 8th, BIOSE108 Therapeutic approaches in AD: -Beta and gamma secretase inhibitors -Abeta immunotherapy -Tau -Ongoing treatments in AD b- and g-secretase : possible therapeutic…
November 29th Therapeutic approaches in AD: -Beta and gamma secretase inhibitors -Abeta immunotherapy -Tau -Tau immunotherapy -Ongoing treatments in AD Model for g-secretase…