Origins and impact of constraints in evolution of gene families Boris E. Shakhnovich and Eugene V.Koonin Genome Research 2006, October 19 Stella Veretnik Journal Club November…

A new selectable marker gene The GUSPlusTM project A new GUS gene, Available under BIOSTM licensing, Pioneering use of the BioForgeTM concept Why do we want extra-cellular…

Origins and impact of constraints in evolution of gene families Boris E. Shakhnovich and Eugene V.Koonin Genome Research 2006, October 19 Stella Veretnik Journal Club November…

* * Multiple sequence alignment * * Copyright notice Many of the images in this power point presentation are from Bioinformatics and Functional Genomics by Jonathan Pevsner…

Multiple sequence alignment Multiple sequence alignment: outline [1] Introduction to MSA Exact methods Progressive (ClustalW) Iterative (MUSCLE) Consistency (ProbCons) Structure-based…

Multiple sequence alignment Multiple sequence alignment: definition • a collection of three or more protein (or nucleic acid) sequences that are partially or completely…

Multiple sequence alignment Monday, December 8, 2008 Introduction to Bioinformatics ME:800.707 J. Pevsner [email protected] Many of the images in this powerpoint…

Multiple Sequence Alignment (MSA) Uses of MSA Technical difficulties Select sequences Select objective function Optimize the objective function Exact algorithms Progressive…

Pathophysiology in the Treatment of Type 2 Diabetes Newer Agents Part 4 of 5 Exenatide Exendin-4, isolated from Gila monster saliva, shares 53% of its amino acid identity…

Opioid receptors belong to the large superfamily of seven transmembrane spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological…