Slide 1Methods course Multiple sequence alignment and Reconstruction of phylogenetic trees Burkhard Morgenstern, Fabian Schreiber Göttingen, October/November 2007 Slide…

Multiple alignment: Feng-Doolittle algorithm Bioinformatics I Fall 2002 Why multiple alignments? Alignment of more than two sequences Usually gives better information about…

Slide 1 Hidden Markov Models Usman Roshan BNFO 601 Slide 2 Hidden Markov Models Alphabet of symbols: Set of states that emit symbols from the alphabet: Set of probabilities…

Slide 1 Expected accuracy sequence alignment Usman Roshan Slide 2 Optimal pairwise alignment Sum of pairs (SP) optimization: find the alignment of two sequences that maximizes…

Expected accuracy sequence alignment Usman Roshan Optimal pairwise alignment Sum of pairs (SP) optimization: find the alignment of two sequences that maximizes the similarity…

Methods course Multiple sequence alignment and Reconstruction of phylogenetic trees Burkhard Morgenstern, Fabian Schreiber Göttingen, October/November 2007 Tools for multiple…