Psychopharmacology[Instructor name]
[Class name section number]
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Introduction
Psychoactive DrugsCommunication between neurons
Neurotransmitter ActivityAgonists – increaseAntagonists – decrease
Side Effects
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Pharmacokinetics
Drug effects in the body Absorption Distribution Metabolism Excretion
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Drug Administration
AbsorptionSlowest: OralFastest: Intravenous/Inhalation
Rapid Absorption =high abuse potential
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Drug Metabolism
Liver enzymes
Repeated exposure Tolerance
Enzyme induction
Dangers of grapefruit juice
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Treatment Approaches
Pharmacology + Therapy = Most Effective
Medication can be problematic due to individual variations.
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
Juveniles and Psychopharmacology
High prevalence Difficult to prescribe and research
Increase in diagnoses
The Elderly and Psychopharmacology
Rapidly aging population
Polypharmacy
Risks
Overview
• Introduction• Pharmacokinetics• Drug Administration• Drug Metabolism• Treatment Approaches– Discussion
• Special Populations and Psychopharmacology• Activity
SSRIs, Suicidality, Violence, and Mania
Why doesn’t everyone just take a “happy pill”?
Serious side-effects
What are other barriers to drug therapies?
Medication AdherenceEasy as can be… right?
Diagnosis: HIV
Treatment: Kool-Aid packets/tic-tac mints
Must adhere to the assigned treatment protocol
What will make treatment easier/harder?
Photo AttributionSlide 1
Photo Credit: Seth Anderson http://www.flickr.com/photos/44124372363@N01/7752724816 https://creativecommons.org/licenses/by-sa/2.0/
Slide 5Photo Credit: anitacanita https://www.flickr.com/photos/86508273@N00/631386556/ https://creativecommons.org/licenses/by-nc-nd/2.0/
Slide 9 Photo Credit: Eme. http://pixabay.com/en/grapefruit-rose-sour-fruit-343615/
Slide 11Photo Credit: Barack Obama https://www.flickr.com/photos/94975828@N00/6774968388/ https://creativecommons.org/licenses/by-nc-sa/2.0/
Slide 11Photo Credit: torbakhopper HE DEAD https://www.flickr.com/photos/gazeronly/129649817/ https://creativecommons.org/licenses/by/2.0/
Slide 11Photo Credit: Jobopa https://www.flickr.com/photos/43904604@N06/13041631074/ https://creativecommons.org/licenses/by-nc-nd/2.0/
Slide 11Photo Credit: Otabi kitahachi https://www.flickr.com/photos/otabi/3947682278/ https://creativecommons.org/licenses/by-nc-sa/2.0/
Slide 11Photo Credit: paolovalde https://www.flickr.com/photos/35034358028@N01/2581632664/ https://creativecommons.org/licenses/by-nc-nd/2.0/
Slide 11Photo Credit: liber https://www.flickr.com/photos/51035655291@N01/200858281/ https://creativecommons.org/licenses/by-sa/2.0/
Slide 12 Photo Credit: Alan Cleaver https://www.flickr.com/photos/11121568@N06/4102645583/ https://creativecommons.org/licenses/by/2.0/
Slide 14Photo Credit: Rosie O'Beirne http://www.flickr.com/photos/rosieobeirne/4090200924/ https://creativecommons.org/licenses/by-nc-nd/2.0/
Slide 15 Photo Credit: WarzauWynn https://www.flickr.com/photos/94246031@N00/4416203874/ https://creativecommons.org/licenses/by-nc/2.0/
Slide 17Phot Credit: Sharon Drummond http://www.flickr.com/photos/28085418@N07/5159112853 https://creativecommons.org/licenses/by-nc-sa/2.0/
Slide 18 Photo Credit: Auntie P https://www.flickr.com/photos/32625013@N00/3177877243/ https://creativecommons.org/licenses/by-nc-sa/2.0/