Lipid Metabolism
By
Amr S. Moustafa, M.D.; Ph.D.
Structure of common Lipid classes
Overview of lipid digestion
lipid metabolism:Hormonal control
Lipid absorption: Mixed micelle
Secretion of Lipids from Entrocytes as Chylomicron
Chylomicron Metabolism
Triacylglycerol synthesis and degradation
Production of cytosolic acetyl CoA
Acetyl Co A carboxylase: Allosteric regulation
Acetyl Co A carboxylase: Covalent modification
De novo synthesis of palmitate
Malic enzyme:NADPH production
The relation between glucose metabolism and palmitate synthesis
Pathways for Glycerphosphate Production
Synthesis of
Triacylglycerol
Common PrecursorFor
TG and PLSynthesis
Hormone-sensitive lipase: Hormonal regulation
Carnitine Shuttle
β-Oxidationof
Fatty Acid
Propionyl CoAMetabolism
Phytanic acid
Ketogenesis
KetolysisKetogenesis
Structure of someglycerophospholipids
Sphingomyelin
Phosphatidylcholinesynthesis
Intracellular Signaling by Inositol triphosphate
PI glycan membrane protein anchor
Phospholipases