Controversies in Controversies in Contemporary Trauma Contemporary Trauma
ResuscitationResuscitation
Ronald V. Maier, M.D., F.A.C.S.Ronald V. Maier, M.D., F.A.C.S.
Ernest E. Moore, M.D., F.A.C.S.Ernest E. Moore, M.D., F.A.C.S.
Controversial PeopleControversial People
John Holcomb, MDJohn Holcomb, MD2009 Memorial Trauma Symposium 2009 Memorial Trauma Symposium
Keynote SpeakerKeynote Speaker
1:1:1 Component Therapy
Component Therapy:1U PRBC + 1U PLT + 1U FFP + 1 U cryo 680 COLDCOLD mL
•Hct 29%•Plt 80K•Coag factors 65% of initial concentration
•1000 mg Fibrinogen
WWB:WWB:
500 mL 500 mL WarmWarm
Hct: 38-50%Hct: 38-50%
Plt: 150-400KPlt: 150-400K
Coag: 100%Coag: 100%
1000 mg Fibrinogen1000 mg Fibrinogen•Armand & Hess, Transfusion Med. Rev., 2003
The Impact ofThe Impact of Hypertonic Hypertonic Saline Resuscitation Saline Resuscitation on the on the Gene Expression Profile of Gene Expression Profile of Critically Injured PatientsCritically Injured Patients
Ang DN, Maier RVAng DN, Maier RV