Wrap Up Sk 1 Blok IPT a-6

8/18/2019 Wrap Up Sk 1 Blok IPT a-6

1/23

WRAP UP SKENARIO 1

BLOK INFEKSI DAN PENYAKIT TROPIK

“DEMAM SORE HARI”

KELOMPOK A-6

Ketua : Aka! F"t!"a#t$ %11&'&1(&1)*

Seke!ta!"+ : A#," Au"a A!" Nu!,e." %11&'&1(&'1*

A#//$ta : Aea#" Yu"ta+a!" %11&'&1(&&1*

A,"#u/!a0a Ata,"#ata %11&'&1(&1(*

A#//!"a#" Ra0a2u %11&'&1(&'(* A+a 3ea Ka!u#"a.a#%11&'&1(&)6*

A##"+a I4t"ta0u5a##a0 %11&'&1&))*

A!2 Fa,0"a0 A!"e4 %11&'&1&)7*

At"ka Au"a %11&'&1&6*

FAKULTAS KEDOKTERAN UNI8ERSITAS YARSI

9LLET9END SUPRAPTO;


2/23

I SKENARIO

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,"a/#$+"+ ,a# ?a!a >e#a#/a#a##2a


3/23

II Kata +u"t

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- ,ea "#te!"tte# : +u0u tuu0 #a"k tu!u# +e>a#5a#/ 0a!"

- ,ea !ea>+ : ,ea 2a#/ ,""kut" >e!"$,e ea+ ,ea u#tuk ee!a>a 0a!" keu,"a#

,""kut" $e0 ke#a"ka# +u0u +e>e!t" +eua

ka!e#a a,a +"4at k0u+u+ ,a!" akte!" 2a#/ e#2e!a#/ "$ka!,

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6 ka!e#a a,a akte!"

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1& >ee!"k+aa# ,a!a0


4/23

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5/23

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akte!" /!a #e/at"4; 2a"tu Salmonella typhi 2a#/ e#2eaka# ,ea t2>0$",

8I Sa+a!a# Bea5a!


6/23

LI 1 Mea0a" ,a# Me#5ea+ka# te#ta#/ ,ea

LO 11 De4"#"+" ,ea

LO 1' P$a ,ea

LO 1) Et"$$/" ,ea

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LI ' Mea0a" ,a# Me#5ea+ka# te#ta#/ akte!" Salmonella

LO '1 St!uktu!

LO '' Ka+"4"ka+"

LO ') T!a#+"+"

LI ) Mea0a" ,a# Me#5ea+ka# te#ta#/ Dea T2>0$",

LO )1 De4"#"+" ,a# et"$$/"

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LO ' e4ek +a>"#/

LO ) k$#t!a"#,"ka+"

VII. Pea0a+a#


7/23

LI 1 Mea0a" ,a# e#5ea+ka# te#ta#/ Dea

LO 11 ,e4"#"+" ,ea

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"#4ek+" $e0 "k!$$!/a#"+e Atau >a,a >e5au >!$+e+ #$#-"#4ek+"; +e>e!t" !a,a#/ atau >ee>a+a#

a0a#-a0a# te!te#tu; +e>e!t" >a,a euk""a Su0u >a+"e# "a+a#2a ,uku! ,e#/a# te!$ete! a"!

!ak+a; ,a# te>at >e#/a"a##2a ," ak+"a; $!a atau !ektu B"a+a#2a te!,a>at >e!e,aa# a#ta!a

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a,aa0 +uat kea,aa# ke#a"ka# +u0u tuu0 +a>a" +et"#//" 1;'$?; +e,a#/ka# 0">$te!"a a,aa0

kea,aa# +u0u tuu0 ,"a.a0 )($?

LO 1' P$a ,ea

Te>at >e#/uku!a#

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%$


8/23

1 Dea +e>t"k

Pa,a t">e ,ea +e>t"k; +u0u a,a# e!a#/+u! #a"k ke t"#/kat 2a#/ t"#//" +eka" >a,a aa 0a!" ,a#

tu!u# kea" ke t"#/kat ,"a ata+ #$!a >a,a >a/" 0a!" Se!"#/ ,"+e!ta" keu0a# e#//"/" ,a#

e!ke!"#/at B"a ,ea t"#//" te!+eut tu!u# ke t"#/kat 2a#/ #$!a ,"#aaka# 5u/a ,ea 0ekt"k

' Dea !e"te#

Su0u a,a# ,a>at tu!u# +et"a> 0a!" teta>" t",ak >e!#a0 e#?a>a" +u0u a,a# #$!a Pe!e,aa#

ke#a"ka# +u0u t",ak +ee+a! ,ea +e>t"k

) Dea "#te!"te#

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,ua 0a!" +eka" ,"+eut te!+"a#a ; ,a# "a te!5a," ,ua 0a!" ea+ ,ea ," a#ta!a ,ua +e!a#/a# ,ea

,"+eut kua!ta#a a#5a#/ 0a!" t",ak e!e,a e"0 ,a!" +atu ,e!a5at Pa,a t"#/kat ,ea 2a#/ te!u+e#e!u+ t"#//" ,"+eut 0">e!>"!ek+"a

( Dea +"k"k

Ke#a"ka# +u0u a,a# +eaa ee!a>a 0a!" 2a#/ ,""kut" $e0 >e!"$,e ea+ ,ea u#tuk ee!a>a

0a!" keu,"a# ,""kut" $e0 ke#a"ka# +u0u +e>e!t" +eua

LO 1) Et"$$/" ,ea


9/23

Dea uu#2a te!5a," ak"at a,a#2a /a#//ua# >a,a 0">$taau+ Pe#2ea#2a ,"a/"

e#5a," ' 2a"tu e!a+a ,a!" "#4ek+" ,a# #$# "#4ek+" :

Et"$$/" I#4ek+"

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e Oat ; eta$"+; ,4 Ke!a?u#a# atau $e! ,$+"+ $at

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te>e!atu! +e>e!t" 0eat +t!$ke; >e!,a!a0a# $tak; k$a; ,Pa,a >e!,a!a0a# "#te!#a >a,a +aat

te!5a,"#2a !ea+$!+" ,a!a0 ,a>at >ua e#2eaka# >e#"#/kata# te>e!atu!


10/23

Infeksi atauperadangan

Makrofag

PirogenEndoge

nProstaglandin

Meningkatkantitik patokanhipotalamus

Inisiasi

Respondingin

Meningkatkan

Produksi Panasdan Mengurangi

PengeluaranPanas

Meningkatkan suhutubuh ke

titik patokanbaru =demam

LO 1 Pat$/e#e+"+ ,ea

Dea 2a#/ ,"+eaka# $e0 kua# "aa0 ,e#/a# te!5a,"#2a >e#/eua!a# e#,$t$k+"#

">$>$"+aka!",a 2a#/ e!a+a ,a!" ,"#,"#/ +e kua#; "#" a,aa0 ata+ >e#/a!u0 #eut!$>0"; ,a# +e-+e

a"# ,a# e!a#/+a#/ "$+"#te+"+ >"!$/e# e#,$/e# Keu,"a# a+uk ke ,aa +u+u#a# +a!a4 >u+at;

+e0"#//a e!a/+a#/ >ee>a+a# >!$+ta/a#,"# 2a#/ e!ua0 +et >$"#t >a,a 0">$taau+ Se0"//a

+ta#,a! #$!a >a#a+ tuu0 a#u+"a e#5a," e"0 t"#//" ,a!" #$!a

1 9au! P!$+ta/a#,"# : Pe#"#/kata# +u0u tuu0 e!0uu#/a# a#/+u#/ ,e#/a# t"#/kat +"t$k"# >"!$/e#

2a#/ ,">!$,uk+" u#tuk e#/ata+" e!a/a" !a#/+a#/ Ra#/+a#/a# ek+$/e# +e>e!t" ek+$t$k+"# ,a#

e#,$t$k+"# e#/"#,uk+" euk$+"t u#tuk e#/eua!ka# >"!$/e# e#,$/e# ,a# 2a#/ >$te# ,"a#ta!a#2a

a,aa0 IL-1; IL-6; TNF %tuu$! #e?!$+"+ 4a?t$!*; ,a# IFN %"#te!4e!$#* P"!$/e# e#,$/e# "#" aka# eke!5a >a,a +"+te +2a!a4 >u+at >a,a t"#/kat O!/a#u 8a+?u$+u La"#ae Te!"#a"+ % O8LT *

2a#/ ,"ke""#/" $e0 a/"a# e,"a ,a# ate!a #u?eu+ >!e$>t"k; 0">$taau+ a#te!"$!; ,a# +e>tu

>au+$u Sea/a" !e+>$# te!0a,a> +"t$k"# te!+eut aka >a,a O8LT te!5a," +"#te+"+ >!$+ta/a#,"#;

te!utaa >!$+ta/a#,"# E' eau" eta$"+e a+a a!ak",$#at 5au! +"k$$k+"/e#a+e ' % !$,uk $ka

a?!$>0a/e "#4aat$!2 >!$te"#-1 %MIP-1*; +uatu ke$k"# 2a#/ eke!5a +e?a!a a#/+u#/ te!0a,a>

0">$taau+ a#te!"$!; ,ea eau" akt""ta+ MIP-1 t",ak ,a>at ,"0aat $e0 a#t">"!et"k


11/23

LI ' Mea0a" ,a# e#5ea+ka# te#ta#/ akte!" Salmonella

LO '1 +t!uktu!

Be!e#tuk ata#/; t",ak e!+>$!a; e!+"4at #e/at"4 >a,a >e.a!#aa# 3!a

Uku!a# Sa$#ea e!a!"a+" 1);( J @ &;(&;C J

Be+a! k$$#" !ata-!ata '

Sea/"a# e+a! "+$at $t" ,e#/a# 4a/e >e!"t!"k

Tuu0 >a,a +ua+a#a ae!$ ,a# 4akutat"4 a#ae!$ >a,a +u0u 1(1 < %+u0u >e!tuu0a# $>t"a

);( H >e!tuu0a# 6C

Mu,a0 tuu0 >a,a e,"u +e,e!0a#a; "+a#2a /a!a e>e,u

T",ak ,a>at tuu0 ,aa a!uta# K


12/23

A#t"/e# 8" atau K: te!etak ," ua! a#t"/e# O; e!u>aka# >$"+aka!",a ,a# 2a#/ a"##2a e!u>aka#

>!$te"# A#t"/e# K ,a>at e#//a#//u a/ut"#a+" ,e#/a# a#t"+e!u O; ,a# ,a>at e!0uu#/a# ,e#/a#

"!ue#+" Da>at ,"",e#t"4"ka+" ,e#/a# u5" >ee#/kaka# ka>+u ,e#/a# a#t"+e!u +>e+"4"k

A#t"/e# H: te!,a>at ," 4a/e ,a# ,",e#atu!a+" atau ,"!u+ak $e0 >a#a+ ,a# ak$0$ A#t"/e#

,">e!ta0a#ka# ,e#/a# ee!"ka# 4$!a"# >a,a ee!a>a akte!" 2a#/ $t" A#t"/e# H

e!a/ut"#a+" ,e#/a# a#t"-H ,a# I/3 Pe#e#tu ,aa a#t"/e# H a,aa0 4u#/+" +ekue#+ a+a a"#$ >a,a >!$te"# 4a/e %4a/e"#* A#t"/e# H >a,a >e!ukaa# akte!" ,a>at e#//a#//u a/ut"#a+"

,e#/a# a#t"$," a#t"/e# O

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Ke0"a#/a# a#t"/e# O ,a>at e#"uka# >e!ua0a# e#tuk k$$#" 2a#/ 0au+ e#5a," ka+a!

A#t"/e# 8" atau K ,a>at 0"a#/ +ea/"a# atau +eu!u0#2a ,aa >!$+e+ t!a#+,uk+"

LO '' ka+"4"ka+"

K"#/,$ : Bakte!"a

P02u : P!$te$akte!"a

e?"e+ : Sa$#ea t02>$+a

Se?a!a >!akt"+ +a$#ea ,a>at ,"a/" e#5a,":

Sa$#ea t"4$", 2a"tu Sa$#ea t2>0"; S>a!at2>0" A; B; ,a# < >e#2ea ,ea e#te!"? %t2>0$",*

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Sa$#ea #$#-t"4$", 2a"tu S Du"# %+a>"*; S ?0$e!a +u"+ %a"* ; S/a"#a!u ,a# S>ua!u

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5e#"+ 0e.a# te!te#tu 5a!a#/ e#"uka# >e#2ak"t >a,a a#u+"a

LO ') t!a#+"+"

Ma#u+"a te!"#4ek+" Sa$#ea t2>0" +e?a!a 4e?a-$!a T",ak +eau Sa$#ea t2>0" 2a#/ a+uk ke

+au!a# ?e!#a aka# e#2eaka# "#4ek+" ka!e#a u#tuk e#"uka# "#4ek+"; Sa$#ea t2>0" 0a!u+

,a>at e#?a>a" u+u+ 0au+ Saa0 +atu 4akt$! >e#t"#/ 2a#/ e#/0aa#/" Sa$#ea t2>0" e#?a>a"

u+u+ 0au+ a,aa0 kea+aa# au#/ B"a kea+aa# au#/ e!ku!a#/ atau aka#a# te!au ?e>atee.at" au#/; aka 0a "#" aka# eu,a0ka# "#4ek+" Sa$#ea t2>0"

LI ) Mea0a" ,a# e#5ea+ka# te#ta#/ ,ea t2>0$",

LO )1 ,e4"#"+"

Dea t"4$", a,aa0 "#4ek+" akut >a,a +au!a# >e#?e!#aa# 2a#/ ,"+eaka# $e0 +a$#ea

t2>0" Dea >a!at"4$", a,aa0 >e#2ak"t +e5e#"+ 2a#/ ,"+eaka# $e0 +a$#ea >a!at2>0" A; B; e#2ak"t te!+eut 0a>"! +aa; teta>" e#"4e+ta+" k"#"+ >a!at"4$", e"0

!"#/a# Ke,ua >e#2ak"t te!+eut ,"+eut t"4$",

%W",$2$#$ '&&( Pe#2ak"t T!$>"+ 9aka!ta : E!a#//a*


13/23

T02>u+ a,$"#a"+; >e#2ea#2a "aa0 +a$#ea t02>$+a Daa a+2a!akat ,"ke#a

+ea/a" t02>u+ teta>" ,aa ,u#"a ke,"kte!a# ,"+eut t02>$", 4ee!; atau t02>u+ a,$"#a"+G ka!e#a

>a,a uu#2a kua# e#2e!a#/ u+u+; aka u+u+ "a+ 5a," ka# ,a# e#2eaka# >e#,a!a0a#

+e!ta "a+ >ua te!5a," ke$?$!a# u+u+

LO )' e>",e"$$/"

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)1 & ta0u# 1& '& ; u+"a & ta0u# ( 1&

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keu#/k"#a# a4!"ka +eata# %"#+",e#+ 1&& ka+u+ >e! 1&&&&& >$>ua+" >e! ta0u#* I#+",e# ,ea

t2>0$", 2a#/ te!/$$#/ +e,a#/ e!a,a ," ."a2a0 a4!"ka; ae!"ka at"#; ,a# $?ea#"a %1&-1&& ka+u+ >e!

1&&&&& >$>ua+" >e! ta0u#* I#+",e# ," a/"a# ,u#"a a"##2a te!#a+uk 2a#/ !e#,a0 %1& ka+u+ >e!

1&&&&& >$>ua+" >e! ta0u#*


14/23

LO )) >at$/e#e+"+


15/23

Ma#u+"a 2a#/ te!"#4ek+" akte!" Sa$#ea T2>0" ,a>at e#/ek+k!e+"ka##2a eau" +ek!et +au!a#

#a4a+; u!"# ,a# t"#5a ,aa 5a#/ka .aktu 2a#/ e!a!"a+"Pat$/e#e+"+ ,ea t"4$", e"atka#

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eekt!$"t ,a# a"! ke ue# "#te+t"#a Bakte!" Sa$#ea T2>0" e!+aa aka#a# atau "#ua#

a+uk ke ,aa tuu0 eau" uut

Pa,a +aat ee.at" au#/ ,e#/a# +ua+a#a a+a a#2ak akte!" 2a#/ at"Bakte!" 2a#/ a+"0

0",u> aka# e#?a>a" u+u+ 0au+; eekat >a,a +e uk$+a keu,"a# e#/"#a+" ,a# e#eu+

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16/23

- M"#//u Pe!taa %a.a te!"#4ek+"*

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17/23

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18/23

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19/23

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