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When Heredity Does Not Follow Mendelian Rules
32

When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Apr 01, 2015

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Deven Cotter
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Page 1: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

When Heredity Does Not Follow Mendelian Rules

Page 2: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Complex Patterns of HeredityIncomplete Dominance

R R

R'

R' RR

RR

R'R'

R'R'

Neither phenotypes is completely dominant

R = RedR = Red

RR'' = White = White

RRRR'' = Pink = Pink

RR = RedRR = Red

RR''RR'' = White = White

Page 3: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Incomplete Dominance

R

R

R'

R’

R

R

RR

R'R'

R'

R'

Neither phenotypes is completely dominant

R = RedR = Red

RR'' = White = White

RR = RedRR = Red

RR''RR'' = White = White

RRRR'' = Pink = Pink

Page 4: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Codominance

Both possible phenotypes can be expressed

R

R

R'

R’

R

R

RR

R'R'

R'

R'

Both phenotypes are expressed in heterozygotes

R = RedR = RedRR'' = White = White

RR = RedRR = Red

RR''RR'' = White = White

RRRR'' = Spotted = Spotted StripedStriped CheckeredCheckered Etc.Etc.

Page 5: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Phenotypes from Multiple AllelesTraits controlled by multiple alleles

B

b

B

b

B

B

bB

bb

b

B

Page 6: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

B = Blue FeathersB = Blue Feathers

b = Chocolate Feathersb = Chocolate Feathers

BBAA = Ash-red Feathers = Ash-red Feathers

B dominant to bB dominant to b

B recessive to BB recessive to BAA

b recessive to Bb recessive to B

b recessive to Bb recessive to BAA

Page 7: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Phenotypes from Multiple AllelesTraits controlled by multiple alleles

BA

b

B

b

B

BA

bBA

bb

b

B

Page 8: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Phenotypes from Multiple AllelesTraits controlled by multiple alleles

BA

B

B

b

B

BA

BBA

bb

B

B

Page 9: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Phenotypes from Multiple AllelesTraits controlled by multiple alleles

BA

BA

b

b

BA

BA

BABA

bb

b

b

Page 10: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex Determination22 Pairs of Homologous Chromosomes: Autosomes

X

X

Y

X

X

X

XX

YX

Y

X

1 Pair of Sex Chromosomes

Page 11: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex Linked InheritanceTraits located on sex chromosomes: Sex-linked

traits

Xr

XR

Y

XR

XR

Xr

XRXr

YXR

Y

XR

XXRR = Red Eyes = Red Eyes

XXrr = White Eyes = White Eyes

Males = ½ Red EyesMales = ½ Red Eyes

Males = ½ White EyesMales = ½ White Eyes

Females = All Red EyesFemales = All Red Eyes

Page 12: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Polygenic InheritanceTraits controlled by multiple genes

AA BB CC

AA BB CC

aa bb cc

aa bb cc

AAAABB BB CCCC AAaaBB bb CC cc

AAaaBB bbCCcc aaaa bb bb cc cc

Page 13: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sickle-Cell Disease

H

H'

H

H’

H

H

H'H

H'H'

H'

H

Codominance

Page 14: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sickle-Cell Disease

H

H'

H’

H'

H'

H

H'H

H'H'

H'

H'

Page 15: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sickle-Cell Disease

H

H’

H’

H’

H’

H

H’H

H’H’

H’

H’

Page 16: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Alleles and Blood Type

Page 17: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Alleles and Blood Type

Page 18: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Multiple Alleles and Blood Type

Page 19: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex-Linked Traits in Humans

Color Blindness

XR XG

XR XG

Xr Xg

Y

XR XG XR XG

XR XG Xr Xg Xr Xg

Y

Y

XR XG

Page 20: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex-Linked Traits in Humans

Hemophilia: 1:10,000 males1:100,000,000 females

XH

Xh

Y

XH Y

Y

XH

XH Xh Xh

XH

XH

Page 21: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex-Linked Traits in Humans

Hemophilia: 1:10,000 males1:100,000,000 females

Xh

Xh

Y

XH Y

Y

Xh

XH Xh Xh

Xh

XH

Page 22: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex-Linked Traits in Humans

Hemophilia: 1:10,000 males1:100,000,000 females

Xh

Xh

Y

XH Y

Y

Xh

XH Xh Xh

Xh

XH

Page 23: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex-Linked Traits in Humans

Hemophilia: 1:10,000 males1:100,000,000 females

Xh

Xh

Y

Xh Y

Y

Xh

Xh Xh Xh

Xh

Xh

Page 24: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Changes in Chromosome Numbers in Humans

46

23 23

Meiosis, Anaphase (normal)

Page 25: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Changes in Chromosome Numbers in Humans

46

23 23

Fertilization

Normal

Page 26: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Changes in Chromosome Numbers in Humans

46

24 22

Meiosis, Anaphase

Down Syndrome: Trisomy 21

Page 27: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Changes in Chromosome Numbers in Humans

47

24 23

Fertilization

Page 28: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Changes in Chromosome Numbers in Humans

45

22 23

Fertilization

Page 29: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Abnormal Number of Sex Chromosomes

Page 30: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Sex Determination22 Pairs of Homologous Chromosomes: Autosomes

X

XX

Y

XXX

YX

Y

Result of Non-disjunction

X X

Page 31: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Trisomy(21) Down Syndrome

Monosomy: Turner Syndrome

Hexapoid: Wheat

Trisomy(13) Patau’s Syndrome

Triploid: Apples

Polyploid: chrysanthamums

Page 32: When Heredity Does Not Follow Mendelian Rules. Complex Patterns of Heredity Incomplete Dominance RR R' RR RR Neither phenotypes is completely dominant.

Tool of Genetics

Punnett Square

Pedigree

Karotype

DNA Fingerprinting