Ueda 2016 diabetes atlas - nam cho

Diabetes Atlas:What behind numbers

Nam H. Cho, MD,PhD,CCD

Professor & Chairman of Preventive Medicine

Ajou University School of Medicine, Suwon Korea

President - Elect, International Diabetes Federation

Chairman of IDF Diabetes Atlas Committee

There are three

main types of diabetes: Type 1 diabetes, type 2 diabetes

and gestational diabetes

Poorly managed

diabetes

leads to serious

complications and early death

With good self-management and

health professional

support, people with diabetes can

live a long, healthy life

Diabetes: A global emergency

IDF Diabetes Atlas, 7th edition

Estimated number of people with diabetes worldwide and per region in 2015 and 2040 (20-79 years)

Diabetes around the world


Men and women with diabetes


≈52

Diabetes in urban and rural environments


65%74.5%

Diabetes prevalence by IDF region


IDF regions by age-adjusted comparative prevalence (%) of diabetes (20-79 years), 2015 and 2040

AFR – Africa regionEUR – European regionMENA – Middle East and North African regionWP – West Pacific region

NAC – North American and Caribbean regionSACA – South and Central American regionSEA – South East Asia region


Middle East and North Africa


One in 7 adults have diabetes in Egypt

Diabetes (20-79 years)2015 2040

Number of people with diabetes

(diagnosed and undiagnosed)

7.8 million

(3.8-9.0 million)

15.1 million

(7.3-17.3 million)

Raw country prevalence14.8%

(7.2-17.1%)

17.8%

(8.6-20.4%)

Mean diabetes-related expenditure per person

with diabetesUSD 219 USD 218

Number of adults with undiagnosed diabetes3.2 million

(1.5-3.7 million )

6.2 million

(3-7.1 million)

Percent of undiagnosed diabetes 41.20%

Number of deaths due to diabetes78,200

(42,000-87,800)

Percent of deaths before age 60 43.60%

Top 10 countries


Top ten countries/territories for number of people with diabetes (20-79 years), 2015 and 2040

One in two adults with

diabetes is

undiagnosed

Undiagnosed diabetes


Undiagnosed diabetes


Proportion and number of people (20-79 years)living with diabetes who are undiagnosed, 2015

IDF region Proportion undiagnosed Number of undiagnosed people with diabetes

Methodology

How the number was calculated?

Methodology

Methodology


Number of data sources reviewed

Countries and territories where data sources were reviewed with information on diabetes and impaired glucose tolerance in adults (20-79 years)

Methodology


Number of data sources selected

Countries and territories for which data sources were selected for diabetes estimates in adults (20-79 years)

Methodology


Countries and territories with data sources that used oral glucose tolerance tests to estimate diabetes and impaired glucose tolerance prevalence (20-79 years)


Methodology



Countries and territories with data sources less than five years old used for estimating diabetes and impaired glucose tolerance prevalence (20-79 years)

Poorly managed

diabetes leads to

serious

complications and

early death

5.0 million people

died from diabetes

in 2015

Equivalent to one

death every six

seconds


Diabetes accounted

for 14.5% of global

all-cause mortality

among people aged

20 to 79

46.6% of

deaths were

in people

under the

age of 60


Africa

South East Asia

Middle East and North Africa

Western Pacific

South and Central America

North America and Caribbean

Europe

Diabetes and Economy

Estimating diabetes-related health expenditures

To estimate the health expenditures due to diabetes, the following

inputs were used:

1. IDF Diabetes Atlas estimates of diabetes prevalence

2. United Nations population estimates

3. WHO annual health expenditures

4. WHO mortality rates

5. The ratios of healthcare expenditures for people with

diabetes compared to people without diabetes

The ‘R=2’ estimates assume that health care expenditures for

people with diabetes are on average two-fold higher than people

without diabetes

12% of global

health

expenditure is

spent on

diabetes


Proportion of total health expenditure estimated to be spent on diabetes (20-79 years), R=2*, 2015

*The R=2 estimates assume that healthcare expenditures for people with diabetes are on average two-fold higher than people without diabetes

AFR – Africa regionEUR – European regionMENA – Middle East and North African regionWP – West Pacific region

NAC – North American and Caribbean regionSACA – South and Central American regionSEA – South East Asia region

Health Expenditure on diabetes



An estimated

average of

1,622 USD per

person with

diabetes was

spent on

diabetes-related

health

expenditures in

2015



Health Expenditure on diabetes

Global health spending to treat diabetes

55%

673

802

415

642

Global estimates of hyperglycaemia in pregnancy

Hyperglycaemia is the most common metabolic condition in pregnant women

Can affect both mother and child with potentially serious complications

Complications

Birth complications

post partum haemorrhage

hypertensive disorders

obstructed labour and caesarean section

preeclampsia

infant macrosomia

Mother

An increased lifetime risk of

developing T2DM

Child

An increased risk of developing

T2DM later in life

GDM diagnostic criteria

Table can be found in: Linnenkamp U, Guariguata L, Beagley J, Whiting DR, Cho NH. The IDF Diabetes Atlas methodology for estimating global prevalence of hyperglycaemia in pregnancy. Diabetes Res Clin Pract 2014;103:186–96.

No studies

1 study2 studies3-7 studies

>7 studies

• 108 studies from 55 countries included

Studies selection

20.9 million of women worldwide

85.1%

7.4%7.5%

other diabetes detectedprior to pregnancy

other diabetes detectedin pregnancy

GDM

Global burden of HIP

16.2% of live births

Global burden of HIP

0

5

10

15

20

25

30

-

2.0

4.0

6.0

8.0

AFR EUR MENA NAC SACA SEA WP

Age

-ad

just

ed

pre

vale

nce

, %

Ab

solu

te n

um

be

r o

f ca

ses

Mill

ion

s

Regional estimates of HIP in women age 20-49 years by IDF region, 2015

Cases of hyperglycaemia in preganancy Age-adjusted regional prevalence

Age-adjusted global prevalence

South-East Asia6.7 million (32% of all cases globally)

the highest prevalence - 26.3% (24.2% crude)

Regional figures

AFR – African regionEUR – European regionMENA – Middle East and North African regionWP – West Pacific regionNAC – North American and Caribbean regionSACA – South and Central American regionSEA – South East Asia region

0.0%

10.0%

20.0%

30.0%

40.0%

50.0%

-

1.0

2.0

3.0

4.0

5.0

6.0

20-24 25-29 30-34 35-39 40-44 45-49

Pre

vale

nce

of

hy[

erg

lyca

em

ia in

pre

gnan

cy

Cas

es

of

hyp

erg

lysa

em

ia in

pre

gnan

cy/m

illio

n

Woman's age in pregnancy

Absolute and relative number of hyperglycaemia cases globaly, 2015

Cases of hyperglycaemia in pregnancy Prevalence of hyperglycaemia in pregnancy

Age-dependent prevalence

50.2%

41.3%

8.5%

20-29 30-39 40-49

50.2% cases in women aged 20-29 years

Distribution of cases of hyperglycaemia in pregnancy in women by age groups, 2015

Age-dependent prevalence

88% cases in middle- and low-income countries

Regional figures

LIC 9.9%

MIC 78.1%

HIC 12.0%

Distribution of cases of hyperglycaemia in pregnancy in women aged 20-49 by World Bank

country income groups, 2015

LIC MIC HIC

LIC – Low-income countriesMIC – Middle-income countriesHIC – High-income countries

5 million people died

from diabetes Every 2 seconds 1 new DM


Conclusion

• No disease has impacted human life stronger than Diabetes

• Costs are greater than any other disease

• Threaten more life than any other disease

• Diabetes is currently unstoppable

• Early Diagnosis and management is the best remedy

Ueda 2016 diabetes atlas - nam cho

Health & Medicine