Tyler M. Hudish1† Laura I. Opincariu1† Timothy G. Cleaver , … · N-nitroso-tris-chloroethylurea induces pre-malignant squamous dysplasia in mice Tyler M. Hudish1†, Laura I.
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N-nitroso-tris-chloroethylurea induces pre-malignant squamous dysplasia in mice Tyler M. Hudish1†, Laura I. Opincariu1†, Anthony B. Mozer1, Micah S. Johnson1, Timothy G. Cleaver2, Stephen P. Malkoski2, Daniel T. Merrick1, and Robert L. Keith1,2
1Denver Veterans Affairs Medical Center, Department of Medicine, 1055 Clermont Street, Denver, CO 80220 2University of Colorado Denver, Department of Medicine, 12801 East 17th Avenue, Aurora, CO 80045 †These authors contributed equally to this work Running title: NTCU induces premalignant squamous dysplasia in mice Key words: lung cancer, NTCU, squamous cell carcinoma, endobronchial dysplasia Footnotes: Supported by Department of Veterans Affairs Merit Review Program (RLK) and NCI Grant K08-CA131483 (SPM). Corresponding author: Robert L. Keith MD, Denver VA Medical Center, 1055 Clermont Street, Box 151, Denver, CO 80220. Phone: 303-399-8020 extension 4619; Fax: 303-377-5686; E-mail: [email protected] No potential conflicts of interest are disclosed.
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257
Published OnlineFirst November 15, 2011.Cancer Prev Res Tyler M. Hudish, Laura I. Opincariu, Anthony B. Mozer, et al. dysplasia in miceN-nitroso-tris-chloroethylurea induces pre-malignant squamous
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 15, 2011; DOI: 10.1158/1940-6207.CAPR-11-0257