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National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Tuberculosis in the United States 1993–2018* National Tuberculosis Surveillance System Division of Tuberculosis Elimination *Updated as of June 6, 2019
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Tuberculosis in the United States 1993–2018* › tb › statistics › surv › surv2018 › ... · 6/6/2019  · *Updated as of June 6, 2019. Reported Tuberculosis (TB) Cases and

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  • National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention

    Tuberculosis in the United States1993–2018*

    National Tuberculosis Surveillance System

    Division of Tuberculosis Elimination

    *Updated as of June 6, 2019

  • Reported Tuberculosis (TB) Cases and Rates United States, 1993–2018

    Chart1

    19931993

    19941994

    19951995

    19961996

    19971997

    19981998

    19991999

    20002000

    20012001

    20022002

    20032003

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    No. of Cases

    Incidence Rate

    Year

    No. of Cases

    Cases per 100,000 Population

    25102

    9.6576394144

    24207

    9.1997812712

    22726

    8.5346767133

    21210

    7.8732182751

    19752

    7.2445343002

    18286

    6.6288663953

    17499

    6.2711401464

    16308

    5.7796500754

    15945

    5.5953463422

    15055

    5.2342424678

    14836

    5.1139587417

    14499

    4.9517546639

    14062

    4.7584467497

    13727

    4.6005107743

    13277

    4.4075778643

    12886

    4.237505982

    11512

    3.7526298603

    11088

    3.5845667526

    10491

    3.3670324466

    9928

    3.163050493

    9554

    3.0228655033

    9389

    2.9489322976

    9539

    2.9740352011

    9253

    2.8640732857

    9088

    2.7950424325

    9025

    2.7585263881

    Sheet1

    YearNo. of CasesIncidence Rate

    199325,1029.7

    199424,2079.2

    199522,7268.5

    199621,2107.9

    199719,7527.2

    199818,2866.6

    199917,4996.3

    200016,3085.8

    200115,9455.6

    200215,0555.2

    200314,8365.1

    200414,4995.0

    200514,0624.8

    200613,7274.6

    200713,2774.4

    200812,8864.2

    200911,5123.8

    201011,0883.6

    201110,4913.4

    20129,9283.2

    20139,5543.0

    20149,3892.9

    20159,5393.0

    20169,2532.9

    20179,0882.8

    201890252.8

  • Total TB Case Rates andAnnual Percent Change in Rate, 2010–2018

    -6.1 -2.4-4.4 -3.7+0.9 -1.3-2.4

    -6.1

    Year

    Case

    s per

    100

    ,000

    pop

    ulat

    ion

    Chart1

    2010

    2011

    2012

    2013

    2014

    2015

    2016

    2017

    2018

    Series 1

    3.586829737

    3.369600005

    3.16400629

    3.024763891

    2.951130884

    2.976529412

    2.864073286

    2.796887751

    2.759749004

    Sheet1

    Series 1

    20103.586829737

    20113.369600005

    20123.16400629

    20133.024763891

    20142.951130884

    20152.976529412

    20162.864073286

    20172.796887751

    20182.759749004

  • Reported Tuberculosis (TB) Deaths* and Rates United States, 1993–2017

    *National Vital Statistics System Multiple Causes of Death (accessed from CDC Wonder)

    Chart1

    19931993

    19941994

    19951995

    19961996

    19971997

    19981998

    19991999

    20002000

    20012001

    20022002

    20032003

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    No. of Deaths

    Mortality Rate

    Year

    No. of Deaths

    Deaths per 100,000 Population

    1631

    0.6275041783

    1478

    0.5617084611

    1336

    0.5017305328

    1202

    0.4461861559

    1166

    0.4276593253

    1112

    0.403111639

    930

    0.3332853498

    776

    0.2750189145

    764

    0.2680993795

    784

    0.2725769575

    711

    0.2450811988

    657

    0.2243811859

    648

    0.2192770227

    652

    0.2185133696

    554

    0.183911888

    585

    0.1923747477

    529

    0.1724410351

    569

    0.1839482758

    539

    0.1729892754

    510

    0.1624854705

    555

    0.1756008326

    493

    0.1548432871

    470

    0.146534914

    528

    0.1634313947

    515

    0.1583898385

    Sheet1

    YearNo. of DeathsMortality Rate

    19931,6310.6

    19941,4780.6

    19951,3360.5

    19961,2020.4

    19971,1660.4

    19981,1120.4

    19999300.3

    20007760.3

    20017640.3

    20027840.3

    20037110.2

    20046570.2

    20056480.2

    20066520.2

    20075540.2

    20085850.2

    20095290.2

    20105690.2

    20115390.2

    20125100.2

    20135550.2

    20144930.2

    20154700.1

    20165280.2

    20175150.2

  • Percentage of TB Cases by State, United States, 2018

    DC, District of Columbia

    DC

    12.56.5

    23.2

    8.3

  • TB Incidence Rate (per 100,000 persons)

    5.3

    8.53.9

    NYC (6.7)

    D.C. (5.1)

    8.4

  • Map of U.S.-Affiliated Pacific Islands and Hawaiiby TB Case Rates*, 2018

    Northern Mariana Islands

    90.4

    American Samoa

    2.0

    Guam 41.7

    Palau94.4

    Hawaii8.4

    *Cases per 100,000 population

  • TB Cases and Rates Among U.S.-Born versus Non-U.S.–Born Persons, United States, 1993–2018

    Case

    s per

    100

    ,000

    Pop

    ulat

    ion

    Chart1

    1993199319931993

    1994199419941994

    1995199519951995

    1996199619961996

    1997199719971997

    1998199819981998

    1999199919991999

    2000200020002000

    2001200120012001

    2002200220022002

    2003200320032003

    2004200420042004

    2005200520052005

    2006200620062006

    2007200720072007

    2008200820082008

    2009200920092009

    2010201020102010

    2011201120112011

    2012201220122012

    2013201320132013

    2014201420142014

    2015201520152015

    2016201620162016

    2017201720172017

    2018201820182018

    Year

    U.S.-born Cases

    Non-U.S.–born Cases

    U.S.-born Rate

    Non-U.S.–born Rate

    No. of cases

    17433

    7403

    7.3859568104

    34.0305231222

    16181

    7762

    6.7930726176

    36.0779536652

    14663

    8010

    6.0869929806

    38.013657771

    13385

    7752

    5.573758215

    32.0356471788

    11925

    7753

    4.9361111783

    30.8744887321

    10609

    7623

    4.3716824981

    28.8849215329

    9783

    7624

    3.9965217719

    28.135519913

    8632

    7634

    3.5200139196

    26.4711440604

    7848

    8034

    3.1711672175

    27.6426088003

    7263

    7737

    2.922168965

    25.5335689207

    6842

    7948

    2.7062156925

    23.8853184959

    6601

    7875

    2.5944950695

    23.2235482237

    6287

    7745

    2.4513172852

    22.2937226893

    5858

    7845

    2.2739775757

    21.6515821331

    5427

    7779

    2.0890357346

    20.8995579175

    5235

    7642

    2.003575826

    20.1756602493

    4499

    6996

    1.7030557389

    18.7765494532

    4313

    6766

    1.6224410356

    17.6385321477

    3929

    6557

    1.4692386597

    17.0179876262

    3618

    6307

    1.34418128

    15.976094676

    3327

    6218

    1.2263553292

    15.6810120018

    3119

    6264

    1.1432011263

    15.5350985841

    3128

    6406

    1.1416222554

    15.2483129203

    2886

    6361

    1.0470051777

    14.7539253536

    2685

    6395

    0.970094389

    14.7164653752

    2666

    6335

    0.956903809

    14.2839955034

    Sheet1

    U.S.-born CasesNon-U.S.–born CasesU.S.-born RateNon-U.S.–born Rate

    199317,4337,4037.434.0

    199416,1817,7626.836.1

    199514,6638,0106.138.0

    199613,3857,7525.632.0

    199711,9257,7534.930.9

    199810,6097,6234.428.9

    19999,7837,6244.028.1

    20008,6327,6343.526.5

    20017,8488,0343.227.6

    20027,2637,7372.925.5

    20036,8427,9482.723.9

    20046,6017,8752.623.2

    20056,2877,7452.522.3

    20065,8587,8452.321.7

    20075,4277,7792.120.9

    20085,2357,6422.020.2

    20094,4996,9961.718.8

    20104,3136,7661.617.6

    20113,9296,5571.517.0

    20123,6186,3071.316.0

    20133,3276,2181.215.7

    20143,1196,2641.115.5

    20153,1286,4061.115.2

    20162,8866,3611.014.8

    20172,6856,3951.014.7

    20182,6666,3351.014.3

  • Countries of Birth Among Non-U.S.–Born Persons Reported with TB, United States, 2018*

    *Percentages are rounded.

    Chart1

    Other countries

    Haiti

    Guatemala

    China

    Vietnam

    India

    Philippines

    Mexico

    Column1

    0.396

    0.021

    0.032

    0.06

    0.08

    0.099

    0.123

    0.189

    Sheet1

    SalesColumn1

    Other countries0.396

    Haiti0.021

    Guatemala0.032

    China0.06

    Vietnam0.08

    India0.099

    Philippines0.123

    Mexico0.189

  • TB Rates for Top 10 Countries of Birth*United States, 2014–2018

    *The top 10 countries were selected based on their ranked 5-year rate of TB cases by country of birth in the United States. This list of top countries also includes the regions of Eastern Africa and Other Africa.

    † The Eastern Africa region consists of British Indian Ocean Territory, Burundi, Comoros, Djibouti, Europa Island, Glorioso Islands, Juan De Nova Island, Madagascar, Malawi, Mayotte, Mozambique, Reunion, Rwanda, Mauritius, Seychelles, Tromelin Island, and South Sudan. Rwanda and South Sudan were removed from the Eastern Africa region in 2017.

    § The Other Africa region consists of Angola, Botswana, Central African Republic, Chad, Equatorial Guinea, Gabon, Lesotho, Namibia, Sao Tome & Principe, and Swaziland.

    Chart1

    50.80

    51.70

    520

    63.20

    67.70

    71.40

    81.30

    84.20

    90.80

    100.40

    156.80

    160.40

    Y-Values

    Column1

    U.S. Rate/100,000

    []

    []

    [].0

    []

    []

    []

    []

    []

    []

    []

    []

    []

    []

    Other Africa§

    Eastern Africa†

    []

    []

    []

    []

    []

    []

    []

    []

    []

    1

    1

    2

    2

    3

    3

    4

    4

    5

    5

    6

    6

    7

    7

    8

    8

    9

    9

    10

    10

    11

    11

    12

    12

    Sheet1

    X-ValuesY-ValuesColumn1

    Sierra Leone50.810

    Other Africa351.720

    Eastern Africa25230

    Ethiopia63.240

    Fed. States of Micronesia67.750

    Nepal71.460

    Guinea81.370

    Myanmar84.280

    Bhutan90.890

    Somalia100.4100

    Republic of Congo156.8110

    Marshall Islands160.4120

  • Percentage of Non-US–Born TB Casesby Time in the United States at Diagnosis, 2018

    Perc

    enta

    ge o

    f TB

    Case

    s

    Time in the United States

    Chart1

  • Reported TB Cases by Race/Ethnicity,*United States, 2010–2018

    * All races are non-Hispanic; multiple race indicates two or more races reported for a person, but does not include persons of Hispanic/Latino origin.

    Tota

    l No.

    of C

    ases

    Chart1

    20102010201017451549642

    20112011201116381328156

    20122012201215541346557

    20132013201314121246251

    20142014201412401179180

    201520152015123514510244

    20162016201611941117663

    20172017201710579411260

    201820182018107411759

    Year

    Asian

    Hispanic/Latino

    Black/African American

    White

    American Indian/Alaska Native

    Native Hawaiian/Pacific Islander

    Multiple race

    3161

    3220

    2655

    3158

    3001

    2405

    3042

    2788

    2245

    3095

    2697

    2087

    3083

    2748

    2013

    3296

    2700

    1999

    3206

    2597

    1981

    3262

    2570

    1914

    3190

    2617

    1799

    Sheet1

    Column1AsianHispanic/LatinoBlack/African AmericanWhiteAmerican Indian/Alaska NativeNative Hawaiian/Pacific IslanderMultiple raceUnknown/missing

    201031613220265517451549642

    201131583001240516381328156

    201230422788224515541346557

    201330952697208714121246251

    201430832748201312401179180

    2015329627001999123514510244

    201632062597198111941117663

    201732622570191410579411260

    2018319026171799107410411759

  • TB Case Rates by Race/Ethnicity,* United States, 2010–2018

    * All races are non-Hispanic; multiple race indicates two or more races reported for a person, but does not include persons of Hispanic/Latino origin.† Asian race category reporting includes Pacific Islander from 1993–2002; Native Hawaiian/Other Pacific Islander race first reported separately in 2003.¶ Multiple race rates first reported in 2003.

    Case

    s per

    100

    ,000

    pop

    ulat

    ion

    Chart1

    2010201020102010201020102010

    2011201120112011201120112011

    2012201220122012201220122012

    2013201320132013201320132013

    2014201420142014201420142014

    2015201520152015201520152015

    2016201620162016201620162016

    2017201720172017201720172017

    2018201820182018201820182018

    Year

    American Indian/Alaska Native

    Asian†

    Black/African American

    Native Hawaiian/Other Pacific Islander†

    White

    Multiple Race¶

    Hispanic/Latino

    6.7880373624

    21.4127554856

    6.9842810797

    19.2042633465

    0.8840517853

    0.7437264022

    6.3451437807

    5.7662644697

    20.753437855

    6.2659833054

    15.8568265596

    0.8294665322

    0.9615363153

    5.7843828409

    5.7995000312

    19.3937273469

    5.7919596712

    12.4571426381

    0.7863519739

    0.9494578596

    5.2632654016

    5.3197924595

    19.1463984975

    5.33435014

    11.626119014

    0.7143433445

    0.8245423911

    4.9893151513

    4.9769041869

    18.4794344514

    5.0965568391

    16.7417284823

    0.627007229

    1.2556009612

    4.9805139205

    6.1202171031

    19.1330421543

    5.0133845329

    18.3881522611

    0.6243883964

    0.6705963613

    4.7903012793

    4.6509834945

    18.053174087

    4.922568568

    13.4278702514

    0.6036585256

    0.9333087216

    4.5108126977

    3.9125405666

    17.8750304128

    4.7165780177

    19.4340863463

    0.5346517214

    0.865445571

    4.3776380912

    4.3021944087

    17.0327051967

    4.3982939509

    19.9540885416

    0.5436697211

    0.8292729413

    4.3710099919

    Sheet1

    American Indian/Alaska NativeAsian†Black/African AmericanNative Hawaiian/Other Pacific Islander†WhiteMultiple Race¶Hispanic/Latino

    20106.821.47.019.20.90.76.3

    20115.820.86.315.90.81.05.8

    20125.819.45.812.50.80.95.3

    20135.319.15.311.60.70.85.0

    20145.018.55.116.70.61.35.0

    20156.119.15.018.40.60.74.8

    20164.718.14.913.40.60.94.5

    20173.917.94.719.40.50.94.4

    20184.317.04.420.00.50.84.4

  • Reported TB Cases by Origin and Race/Ethnicity*, United States, 2018†

    Non-U.S.-born persons § U.S.–born persons

    * All races are non-Hispanic; multiple race indicates two or more races reported for a person, but does not include persons of Hispanic/Latino origin.† Percentages are rounded.§ American Indian/Alaska Native accounted for

  • Reported TB Cases by Age Group, United States, 1993–2018

    Tota

    l No.

    of C

    ases

    Chart1

    199319931993199319931993

    199419941994199419941994

    199519951995199519951995

    199619961996199619961996

    199719971997199719971997

    199819981998199819981998

    199919991999199919991999

    200020002000200020002000

    200120012001200120012001

    200220022002200220022002

    200320032003200320032003

    200420042004200420042004

    200520052005200520052005

    200620062006200620062006

    200720072007200720072007

    200820082008200820082008

    200920092009200920092009

    201020102010201020102010

    201120112011201120112011

    201220122012201220122012

    201320132013201320132013

    201420142014201420142014

    201520152015201520152015

    201620162016201620162016

    201720172017201720172017

    201820182018201820182018

    Year

    0-4 yrs

    5-14 yrs

    15-24 yrs

    25-44 yrs

    45-64 yrs

    >65 yrs

    1014

    646

    1821

    9589

    6195

    5820

    995

    664

    1832

    9044

    6126

    5540

    894

    642

    1697

    8200

    5960

    5328

    770

    586

    1637

    7564

    5572

    5076

    734

    517

    1675

    6884

    5278

    4663

    638

    439

    1543

    6335

    4954

    4377

    602

    436

    1518

    6062

    4860

    4019

    544

    420

    1618

    5576

    4635

    3515

    543

    386

    1597

    5610

    4515

    3293

    556

    388

    1498

    5288

    4182

    3142

    547

    364

    1573

    5074

    4284

    2994

    549

    403

    1603

    4939

    4193

    2811

    474

    377

    1540

    4737

    4126

    2808

    482

    321

    1532

    4689

    4039

    2663

    467

    310

    1580

    4310

    4036

    2573

    494

    289

    1443

    4238

    3927

    2495

    403

    244

    1279

    3885

    3419

    2282

    365

    270

    1186

    3649

    3415

    2203

    350

    226

    1028

    3362

    3286

    2239

    261

    226

    1019

    3118

    3112

    2191

    294

    188

    978

    2963

    2952

    2179

    263

    195

    961

    2821

    2957

    2192

    244

    196

    936

    2858

    3022

    2283

    223

    163

    935

    2831

    2843

    2255

    227

    202

    846

    2757

    2758

    2294

    186

    186

    874

    2728

    2694

    2354

    Sheet1

    0-4 yrs5-14 yrs15-24 yrs25-44 yrs45-64 yrs>65 yrs

    199310146461821958961955820

    19949956641832904461265540

    19958946421697820059605328

    19967705861637756455725076

    19977345171675688452784663

    19986384391543633549544377

    19996024361518606248604019

    20005444201618557646353515

    20015433861597561045153293

    20025563881498528841823142

    20035473641573507442842994

    20045494031603493941932811

    20054743771540473741262808

    20064823211532468940392663

    20074673101580431040362573

    20084942891443423839272495

    20094032441279388534192282

    20103652701186364934152203

    20113502261028336232862239

    20122612261019311831122191

    2013294188978296329522179

    2014263195961282129572192

    2015244196936285830222283

    2016223163935283128432255

    2017227202846275727582294

    2018186186874272826942354

  • TB Case Rates by Age Group, United States, 1993–2018

    Case

    s per

    100

    ,000

    pop

    ulat

    ion

    Year

    Chart1

    199319931993199319931993

    199419941994199419941994

    199519951995199519951995

    199619961996199619961996

    199719971997199719971997

    199819981998199819981998

    199919991999199919991999

    200020002000200020002000

    200120012001200120012001

    200220022002200220022002

    200320032003200320032003

    200420042004200420042004

    200520052005200520052005

    200620062006200620062006

    200720072007200720072007

    200820082008200820082008

    200920092009200920092009

    201020102010201020102010

    201120112011201120112011

    201220122012201220122012

    201320132013201320132013

    201420142014201420142014

    201520152015201520152015

    201620162016201620162016

    201720172017201720172017

    201820182018201820182018

    5–14 yrs

    0–4 yrs

    15–24 yrs

    25–44 yrs

    45–64 yrs

    ≥65 yrs

    5.1540452113

    1.7482791426

    5.0358514739

    11.607382988

    12.4969042677

    17.7363796185

    5.050733732

    1.7721430272

    5.0701835733

    10.9051313261

    12.0397654231

    16.681463687

    4.5770646363

    1.6917333503

    4.6897119906

    9.8456373363

    11.4107730295

    15.8480344823

    3.9913947602

    1.5243237062

    4.5201459204

    9.0467056632

    10.3741498973

    14.948239512

    3.8430830448

    1.3307249066

    4.5722838634

    8.237172363

    9.5198919025

    13.640322795

    3.3597944353

    1.120741174

    4.1455806485

    7.6103857318

    8.6546158566

    12.7292993368

    3.1780988655

    1.1039307785

    4.018689075

    7.3258160052

    8.2106462584

    11.6357761756

    2.8365402489

    1.0218593227

    4.1053879995

    6.5620581702

    7.424548328

    10.0229349845

    2.8137314447

    0.9379850914

    3.9712962565

    6.6372251506

    7.0009157632

    9.3311783686

    2.8616733007

    0.9432623331

    3.666703505

    6.2959655041

    6.270285656

    8.8451711348

    2.7918923446

    0.8870216163

    3.8005401164

    6.0840786819

    6.2241297801

    8.3483139654

    2.7747053013

    0.9861518585

    3.8213877182

    5.9458148825

    5.9110258239

    7.764481483

    2.3798286925

    0.9285337841

    3.6281248374

    5.7234901788

    5.6414364519

    7.6617066211

    2.4173871726

    0.7910724443

    3.5757762539

    5.6740777778

    5.3698486944

    7.1655159103

    2.3203859771

    0.764381725

    3.6620005903

    5.2236286954

    5.236908271

    6.8022515162

    2.4369636676

    0.7111875486

    3.3255367204

    5.1432064426

    4.9950704366

    6.4341234342

    1.990662361

    0.5974086713

    2.9350391166

    4.725636192

    4.2592319819

    5.7592557891

    1.8079317682

    0.6583459701

    2.7150337646

    4.4395345012

    4.1763167814

    5.4423574306

    1.7392943822

    0.5506080955

    2.3460006337

    4.0782488092

    3.968511324

    5.4143659742

    1.3065635646

    0.5493804544

    2.3181243221

    3.7647852947

    3.7563362222

    5.0792677574

    1.4811669621

    0.4561041928

    2.2230491096

    3.5567850212

    3.5543934904

    4.8814344598

    1.3234467

    0.4735178581

    2.1874869328

    3.3629907152

    3.5477843601

    4.7476937569

    1.2250161348

    0.4770988882

    2.1391546618

    3.3815767275

    3.6060824803

    4.7894070651

    1.1193450175

    0.3970469838

    2.1497180444

    3.3216534954

    3.3785227487

    4.5811001401

    1.1411641694

    0.4918344404

    1.9597398096

    3.2037343574

    3.2768700972

    4.5162882969

    0.9389067037

    0.4528283256

    2.0339393262

    3.1365096135

    3.2107995374

    4.4896937592

    Sheet1

    year0–4 yrs5–14 yrs15–24 yrs25–44 yrs45–64 yrs≥65 yrs

    19935.21.75.011.612.517.7

    19945.11.85.110.912.016.7

    19954.61.74.79.811.415.8

    19964.01.54.59.010.414.9

    19973.81.34.68.29.513.6

    19983.41.14.17.68.712.7

    19993.21.14.07.38.211.6

    20002.81.04.16.67.410.0

    20012.80.94.06.67.09.3

    20022.90.93.76.36.38.8

    20032.80.93.86.16.28.3

    20042.81.03.85.95.97.8

    20052.40.93.65.75.67.7

    20062.40.83.65.75.47.2

    20072.30.83.75.25.26.8

    20082.40.73.35.15.06.4

    20092.00.62.94.74.35.8

    20101.80.72.74.44.25.4

    20111.70.62.34.14.05.4

    20121.30.52.33.83.85.1

    20131.50.52.23.63.64.9

    20141.30.52.23.43.54.7

    20151.20.52.13.43.64.8

    20161.10.42.13.33.44.6

    20171.10.52.03.23.34.5

    20180.90.52.03.13.24.5

  • Distribution of Sex by Age Group, United States, 2018

    Males Females

    =65

    45-64

    25-44

    15-24

    5-14

    =6565%35%15192354.0

    45-6465%35%17432694.0

    25-4458%42%15732728.0

    15-2458%42%504874.0

    5-1444%56%82186.0

    =65

    45-64

    25-44

    15-24

    5-14

    =6535%8282354.0

    45-6435%9482694.0

    25-4442%11462728.0

    15-2442%369874.0

    5-1456%104186.0

  • Pediatric TB Cases by Age Group, 1993–2018

    Chart1

    1993199319931993

    1994199419941994

    1995199519951995

    1996199619961996

    1997199719971997

    1998199819981998

    1999199919991999

    2000200020002000

    2001200120012001

    2002200220022002

    2003200320032003

    2004200420042004

    2005200520052005

    2006200620062006

    2007200720072007

    2008200820082008

    2009200920092009

    2010201020102010

    2011201120112011

    2012201220122012

    2013201320132013

    2014201420142014

    2015201520152015

    2016201620162016

    2017201720172017

    2018201820182018

    Year

  • Number of U.S. Pediatric TB Cases among U.S.-Born and Non-U.S.–Born* Children, 1993–2018

    *Non-U.S.–born refers to persons born outside the United States or its territories or not born to a U.S. citizen

    Chart1

    19931993

    19941994

    19951995

    19961996

    19971997

    19981998

    19991999

    20002000

    20012001

    20022002

    20032003

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    Year

    Non-U.S.–born

    U.S.-born

    Total No. of Cases

    413

    1231

    389

    1249

    354

    1180

    314

    1039

    287

    960

    254

    817

    270

    757

    258

    704

    273

    655

    251

    688

    269

    642

    283

    668

    244

    606

    203

    600

    210

    566

    205

    578

    147

    500

    156

    479

    121

    455

    137

    349

    99

    383

    110

    348

    99

    341

    101

    285

    94

    335

    82

    290

    Sheet1

    Column119931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018

    Non-U.S.–born41338935431428725427025827325126928324420321020514715612113799110991019482

    U.S.-born1231124911801039960817757704655688642668606600566578500479455349383348341285335290

  • Number of U.S. Pediatric TB Cases among U.S.-Born Children by Parent/Guardian Status, 2010–2018

    *At least one parent/guardian was non-U.S.–born

    Chart1

    201020102010

    201120112011

    201220122012

    201320132013

    201420142014

    201520152015

    201620162016

    201720172017

    201820182018

    Year

    U.S.-born with Non-US–born parents/guardians*

    U.S.-born with US-born parents/guardians

    US-born with parents/guardians with unknown origin

    Total No. of Cases

    301

    132

    46

    267

    143

    45

    215

    108

    26

    234

    122

    27

    225

    106

    17

    217

    102

    22

    165

    90

    30

    221

    84

    30

    175

    83

    32

    Sheet1

    Column1201020112012201320142015201620172018

    U.S.-born with Non-US–born parents/guardians*301267215234225217165221175

    U.S.-born with US-born parents/guardians132143108122106102908483

    US-born with parents/guardians with unknown origin464526271722303032

    479455349383348341285335290

    U.S.-born with U.S.-born parents/guardians

  • Number of U.S. TB Cases by Case Verification Criteria, 1993–2018

    Chart1

    19931993199319931993

    19941994199419941994

    19951995199519951995

    19961996199619961996

    19971997199719971997

    19981998199819981998

    19991999199919991999

    20002000200020002000

    20012001200120012001

    20022002200220022002

    20032003200320032003

    20042004200420042004

    20052005200520052005

    20062006200620062006

    20072007200720072007

    20082008200820082008

    20092009200920092009

    20102010201020102010

    20112011201120112011

    20122012201220122012

    20132013201320132013

    20142014201420142014

    20152015201520152015

    20162016201620162016

    20172017201720172017

    20182018201820182018

    Year

    Positive Culture

    Positive NAA Test

    Positive Smear

    Clinical Case

    Provider Diagnosis

    Total No. of Cases

    20306

    0

    185

    3088

    1523

    19508

    0

    189

    2917

    1593

    18265

    0

    189

    2749

    1523

    17154

    0

    131

    2607

    1318

    15980

    0

    155

    2411

    1206

    14789

    0

    155

    2253

    1089

    13994

    0

    172

    2103

    1230

    13013

    0

    148

    1950

    1197

    12750

    0

    123

    1886

    1186

    11974

    0

    104

    1822

    1155

    11684

    0

    116

    1783

    1253

    11327

    0

    80

    1824

    1268

    10954

    0

    96

    1797

    1213

    10744

    0

    93

    1629

    1261

    10422

    0

    69

    1496

    1290

    10017

    18

    60

    1547

    1244

    8878

    57

    73

    1778

    726

    8401

    107

    69

    1866

    645

    8073

    121

    61

    1674

    562

    7619

    118

    38

    1640

    513

    7361

    149

    47

    1509

    488

    7221

    161

    45

    1495

    467

    7412

    173

    44

    1465

    445

    7177

    187

    36

    1411

    442

    7132

    202

    36

    1319

    399

    7062

    277

    37

    1252

    397

    Sheet1

    Positive CulturePositive NAA TestPositive SmearClinical CaseProvider Diagnosis

    199320,30601853,0881,523

    199419,50801892,9171,593

    199518,26501892,7491,523

    199617,15401312,6071,318

    199715,98001552,4111,206

    199814,78901552,2531,089

    199913,99401722,1031,230

    200013,01301481,9501,197

    200112,75001231,8861,186

    200211,97401041,8221,155

    200311,68401161,7831,253

    200411,3270801,8241,268

    200510,9540961,7971,213

    200610,7440931,6291,261

    200710,4220691,4961,290

    200810,01718601,5471,244

    20098,87857731,778726

    20108,401107691,866645

    20118,073121611,674562

    20127,619118381,640513

    20137,361149471,509488

    20147,221161451,495467

    20157,412173441,465445

    20167,177187361,411442

    20177,132202361,319399

    20187,062277371,252397

  • U.S. TB Cases by Site of Disease, 2018

    *Any extrapulmonary involvement which includes cases that are extrapulmonary only and both pulmonary and extrapulmonary.Patients may have more than one disease site but are counted in mutually exclusive categories for surveillance purposes. Note: Percentages are rounded.

    Chart1

    Pulmonary Involvement

    Extrapulmonary Only

    Column1

    []79.6%

    [] []%

    79.6

    20.4

    Sheet1

    Column1

    Pulmonary Involvement79.6

    Extrapulmonary Only20.4

    Chart1

    Other

    Meningeal

    Genitourinary

    Peritoneal

    Bone & Joint

    Pleura

    Lymphatic

    Percent

    0.221

    0.038

    0.048

    0.058

    0.096

    0.169

    0.369

    Sheet1

    Extrapulmonary sitePercent

    Other0.221

    Meningeal0.038

    Genitourinary0.048

    Peritoneal0.058

    Bone & Joint0.096

    Pleura0.169

    Lymphatic0.369

  • Percentage of Tuberculosis Cases*, by Initial Drug Regimen, United States, 1993–2018

    *Alive at diagnosis†Isoniazid, Rifampin, Pyrazinamide and Ethambutol

    Chart1

    199319931993

    199419941994

    199519951995

    199619961996

    199719971997

    199819981998

    199919991999

    200020002000

    200120012001

    200220022002

    200320032003

    200420042004

    200520052005

    200620062006

    200720072007

    200820082008

    200920092009

    201020102010

    201120112011

    201220122012

    201320132013

    201420142014

    201520152015

    201620162016

    201720172017

    201820182018

    Year

    IRZE†

    Other 4+ drug regimen

    Not on a 4+ drug regimen

    Percentage of Cases

    40.3

    4.9

    54.8

    55.7

    5.5

    38.8

    62.7

    4.8

    32.5

    67.3

    4.4

    28.3

    71.9

    4.3

    23.8

    74.3

    4.3

    21.4

    76.9

    4.7

    18.4

    78.5

    4.2

    17.3

    79.8

    3.9

    16.3

    80.3

    4.3

    15.4

    81.3

    4.7

    14

    82.4

    4.9

    12.7

    83.7

    5

    11.3

    83.3

    6.6

    10.1

    83.8

    6.5

    9.7

    84.2

    7.6

    8.2

    84.3

    7.8

    7.9

    84.5

    8.1

    7.4

    85.2

    8.1

    6.7

    85.4

    9

    5.6

    84.6

    9.5

    5.9

    85.3

    9.2

    5.5

    85.4

    9.2

    5.4

    85

    10.1

    4.9

    83.4

    10.4

    6.2

    81.5

    11.9

    6.6

    Sheet1

    IRZE†Other 4+ drug regimenNot on a 4+ drug regimen

    199340.34.954.8

    199455.75.538.8

    199562.74.832.5

    199667.34.428.3

    199771.94.323.8

    199874.34.321.4

    199976.94.718.4

    200078.54.217.3

    200179.83.916.3

    200280.34.315.4

    200381.34.714

    200482.44.912.7

    200583.7511.3

    200683.36.610.1

    200783.86.59.7

    200884.27.68.2

    200984.37.87.9

    201084.58.17.4

    201185.28.16.7

    201285.495.6

    201384.69.55.9

    201485.39.25.5

    201585.49.25.4

    20168510.14.9

    201783.410.46.2

    201881.511.96.6

  • Mode of Treatment Administration Among Persons Reported with TB, United States, 1993–2016*

    Perc

    enta

    ge o

    f All

    Trea

    tmen

    tMod

    es†

    YearDOT, directly observed therapy; SA, self-administered therapy.* Data available through 2016 only.† Percentage of total cases among persons alive at diagnosis, with an initial regimen of one or more drugs prescribed and excluding cases with unknown

    mode of treatment administration.

    Chart1

    199319931993

    199419941994

    199519951995

    199619961996

    199719971997

    199819981998

    199919991999

    200020002000

    200120012001

    200220022002

    200320032003

    200420042004

    200520052005

    200620062006

    200720072007

    200820082008

    200920092009

    201020102010

    201120112011

    201220122012

    201320132013

    201420142014

    201520152015

    201620162016

    2016

    DOT only

    DOT + SA

    SA only

    21.67

    14.38

    63.95

    28.02

    20.49

    51.49

    37.16

    21.43

    41.41

    42.41

    22.38

    35.21

    46.9

    23.78

    29.33

    47.6

    26.54

    25.86

    49.39

    27.59

    23.01

    52.45

    25.8

    21.75

    53.58

    27.49

    18.93

    55.3

    27.72

    16.98

    56.46

    28.45

    15.09

    58.85

    27.71

    13.44

    57.87

    29.58

    12.55

    57.48

    30.36

    12.16

    56.29

    32.89

    10.82

    56.34

    33.5

    10.17

    59.64

    30.26

    10.1

    59.33

    31

    9.67

    62.23

    29.15

    8.62

    61.79

    29.11

    9.09

    63.21

    28.83

    7.96

    63.79

    29.12

    7.09

    65.03

    28.48

    6.49

    64.02

    30.3

    5.68

    Sheet1

    Year)DOT onlyDOT + SASA only

    1993(21.7)(14.4)(64.0)36.0563.95

    1994(28.0)(20.5)(51.5)48.5151.49

    1995(37.2)(21.4)(41.4)58.5941.41

    1996(42.4)(22.4)(35.2)64.7935.21

    1997(46.9)(23.8)(29.3)70.6829.32

    1998(47.6)(26.5)(25.9)74.1425.86

    1999(49.4)(27.6)(23.0)76.9823.02

    2000(52.5)(25.8)(21.8)78.2521.75

    2001(53.6)(27.5)(18.9)81.0718.93

    2002(55.3)(27.7)(17.0)83.0216.98

    2003(56.5)(28.5)(15.1)84.9115.09

    2004(58.9)(27.7)(13.4)86.5613.44

    2005(57.9)(29.6)(12.6)87.4512.55

    2006(57.5)(30.4)(12.2)87.8412.16

    2007(56.3)(32.9)(10.8)89.1810.82

    2008(56.3)(33.5)(10.2)89.8410.16

    2009(59.6)(30.3)(10.1)89.910.1

    2010(59.3)(31.0)(9.7)90.339.67

    2011(62.2)(29.2)(8.6)91.388.62

    2012(61.8)(29.1)(9.1)90.99.1

    2013(63.2)(28.8)(8.0)92.047.96

    2014(63.8)(29.1)(7.1)92.917.09

    2015(65.0)(28.5)(6.5)93.516.49

    2016(64.0)(30.3)(5.7)94.325.68

  • Completion of TB Therapy,United States, 1993–2016*

    *Data available through 2016 only.Note: Includes persons eligible to complete therapy within one year of diagnosis.

    2016

    Chart1

    199319931993

    199419941994

    199519951995

    199619961996

    199719971997

    199819981998

    199919991999

    200020002000

    200120012001

    200220022002

    200320032003

    200420042004

    200520052005

    200620062006

    200720072007

    200820082008

    200920092009

    201020102010

    201120112011

    201220122012

    201320132013

    201420142014

    201520152015

    201620162016

    Year

    Completed in ≤1 year

    Completed

    Did Not Complete

    Percentage Completing Therapy

    63.4

    22.6

    14

    68.6

    18.2

    13.2

    74.1

    15.1

    10.8

    76.8

    13.4

    9.8

    78.7

    12.3

    9

    81.2

    11

    7.8

    81.4

    10.8

    7.8

    82.2

    10.3

    7.5

    82.5

    10.2

    7.3

    83

    9.5

    7.5

    83.6

    9.2

    7.2

    84.3

    8.2

    7.5

    84

    8.5

    7.5

    84.8

    8.4

    6.8

    85.6

    8.3

    6.1

    86.1

    7.2

    6.7

    88.8

    6.8

    4.4

    89.7

    6.4

    3.9

    89.7

    6.7

    3.6

    90.1

    6.3

    3.6

    89.9

    6.4

    3.7

    90.3

    6.5

    3.2

    90

    6.3

    3.7

    89.2

    6.4

    4.4

    Sheet1

    Completed in ≤1 yearCompletedDid Not Complete

    1993(63.4)(22.6)14.0

    1994(68.6)(18.2)13.2

    1995(74.1)(15.1)10.8

    1996(76.8)(13.4)9.8

    1997(78.7)(12.3)9.0

    1998(81.2)(11.0)7.8

    1999(81.4)(10.8)7.8

    2000(82.2)(10.3)7.5

    2001(82.5)(10.2)7.3

    2002(83.0)(9.5)7.5

    2003(83.6)(9.2)7.2

    2004(84.3)(8.2)7.5

    2005(84.0)(8.5)7.5

    2006(84.8)(8.4)6.8

    2007(85.6)(8.3)6.1

    2008(86.1)(7.2)6.7

    2009(88.8)(6.8)4.4

    2010(89.7)(6.4)3.9

    2011(89.7)(6.7)3.6

    2012(90.1)(6.3)3.6

    2013(89.9)(6.4)3.7

    2014(90.3)(6.5)3.2

    2015(90.0)(6.3)3.7

    2016(89.2)(6.4)4.4

  • Isoniazid Resistance Among U.S.-Born versus Non-U.S.–Born Persons, United States, 1993–2018

    Chart1

    19931993

    19941994

    19951995

    19961996

    19971997

    19981998

    19991999

    20002000

    20012001

    20022002

    20032003

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    US-Born

    Non-US-Born

    Year

    No. of Cases

    872

    639

    789

    725

    631

    709

    563

    711

    470

    714

    404

    703

    309

    669

    291

    679

    269

    617

    229

    676

    229

    655

    229

    636

    206

    619

    182

    653

    176

    605

    201

    629

    199

    553

    178

    509

    182

    565

    154

    532

    140

    531

    167

    517

    157

    526

    126

    515

    102

    518

    100

    498

    Sheet1

    Column2US-BornNon-US-Born

    1993872639

    1994789725

    1995631709

    1996563711

    1997470714

    1998404703

    1999309669

    2000291679

    2001269617

    2002229676

    2003229655

    2004229636

    2005206619

    2006182653

    2007176605

    2008201629

    2009199553

    2010178509

    2011182565

    2012154532

    2013140531

    2014167517

    2015157526

    2016126515

    2017102518

    2018100498

  • Cases of MDR TB* by History of TB, United States, 1993–2018

    * Multidrug-resistant TB (MDR TB) is defined as resistance to at least isoniazid and rifampin.

    Chart1

    199319931993

    199419941994

    199519951995

    199619961996

    199719971997

    199819981998

    199919991999

    200020002000

    200120012001

    200220022002

    200320032003

    200420042004

    200520052005

    200620062006

    200720072007

    200820082008

    200920092009

    201020102010

    201120112011

    201220122012

    201320132013

    201420142014

    201520152015

    201620162016

    201720172017

    201820182018

    No previous TB

    Previous TB

    Percentage

    Year

    No. of Cases

    407

    76

    0.025

    353

    74

    0.022

    254

    70

    0.016

    207

    43

    0.013

    155

    44

    0.011

    132

    23

    0.01

    127

    28

    0.01

    120

    26

    0.01

    115

    33

    0.01

    132

    26

    0.012

    94

    21

    0.009

    100

    27

    0.01

    98

    23

    0.01

    103

    20

    0.01

    101

    19

    0.01

    88

    19

    0.009

    95

    19

    0.012

    87

    17

    0.011

    101

    27

    0.013

    77

    12

    0.011

    83

    12

    0.012

    70

    24

    0.01

    72

    16

    0.01

    78

    18

    0.012

    101

    26

    0.016

    79

    17

    0.013

    Sheet1

    No previous TBPrevious TBPercentageNo. of casesTotal cases%

    1993407762.5%407166012.5

    1994353742.2%353164172.2

    1995254701.6%254160231.6

    1996207431.3%207153601.3

    1997155441.1%155144491.1

    1998132231.0%132134201.0

    1999127281.0%127126591.0

    2000120261.0%120118291.0

    2001115331.0%115115141.0

    2002132261.2%132108201.2

    200394210.9%94107520.9

    2004100271.0%100104821.0

    200598231.0%98100651.0

    2006103201.0%10399071.0

    2007101191.0%10196461.0

    200888190.9%8893060.9

    200995191.2%9077391.2

    201087171.1%8777691.1

    2011101271.3%10175541.3

    201277121.1%7770831.1

    201383121.2%8368661.2

    201470241.0%7067461.0

    201572161.0%7269611.0

    201678181.2%7866871.2

    2017101261.6%9762161.6

    201879171.3%

  • HIV Coinfection by Age Among Persons Reported with TB, United States, 2011–2018

    Chart1

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    Year

    All ages

    Ages 25–44 yrs

    Percentage of TB Caseswith HIV Coinfection

    7.4

    10.8

    7.2

    11.4

    6.4

    9.2

    5.9

    8.6

    5.4

    7.5

    5.5

    8.5

    5.5

    9.1

    5.1

    8.3

    Sheet1

    All agesAges 25–44 yrs

    2011(7.4)(10.8)

    2012(7.2)(11.4)

    2013(6.4)(9.2)

    2014(5.9)(8.6)

    2015(5.4)(7.5)

    2016(5.5)(8.5)

    2017(5.5)(9.1)

    2018(5.1)(8.3)

  • Reported TB Case Percentages* by Risk Factor, United States, 2018

    Non-HIV immunosuppression

    Contact to Infectious TB

    Diabetes Mellitus

    Contact to Infectious TB Diabetes Mellitus

    Comparison of Selected Risk Factors by Origin of BirthMost Common Risk Factors Reported Among TB Patients

    *Percentages are rounded

    Chart1

    0.1980.1980.198

    non-HIV immunosuppression

    Contact with Infectious TB

    Diabetes Mellitis

    0.073

    0.077

    0.198

    Sheet1

    Column1

    non-HIV immunosuppression7%

    Contact with Infectious TB8%

    Diabetes Mellitis20%

    Chart1

    0.0420.042

    0.220.22

    US-Born

    Non-US-Born

    []

    []

    0.159

    0.042

    0.146

    0.22

    Sheet1

    US-BornNon-US-Born

    Contact with Infectious TB16%4%

    Diabetes Mellitis15%22%

  • *Correctional facilities include federal prisons, state prisons, local jails, juvenile correctional facilities, other correctional facilities, or unknown type of correctional facility.

    TB Cases among Residents of Correctional Facilities Ages ≥15, 1993–2018*

    Chart1

    19931993

    19941994

    19951995

    19961996

    19971997

    19981998

    19991999

    20002000

    20012001

    20022002

    20032003

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    Number of TB cases

    Percentage of TB cases

    Year

    No. of Cases

    Percentage of TB Cases

    950

    4.0554962647

    1117

    4.9551947476

    937

    4.42294076

    782

    3.9397450753

    747

    4.0378378378

    657

    3.8177697716

    576

    3.4996050793

    587

    3.8255995829

    522

    3.4765234765

    460

    3.2600992204

    476

    3.4183123878

    495

    3.6542152665

    537

    4.0647944894

    508

    3.9309757796

    481

    3.8483078646

    496

    4.0981574816

    464

    4.2705936493

    491

    4.6972161102

    423

    4.2662632375

    391

    4.1419491525

    364

    4.012345679

    377

    4.2212518195

    334

    3.6707330476

    329

    3.7116425993

    268

    3.0964760254

    310

    3.5838150289

    Sheet1

    YearNumber of TB casesTotal TB Cases >15 yrsPercentage of TB cases

    1993950234254.1

    19941117225425.0

    1995937211854.4

    1996782198493.9

    1997747185004.0

    1998657172093.8

    1999576164593.5

    2000587153443.8

    2001522150153.5

    2002460141103.3

    2003476139253.4

    2004495135463.7

    2005537132114.1

    2006508129233.9

    2007481124993.8

    2008496121034.1

    2009464108654.3

    2010491104534.7

    201142399154.3

    201239194404.1

    201336490724.0

    201437789314.2

    201533490993.7

    201632988643.7

    201726886553.1

    201831086503.6

  • TB Cases among Residents of Correctional Facilities Ages ≥15 by Type of Facility, 2010–2018

    *Includes Immigration and Customs Enforcement (ICE) detention centers, tribal jails operated by Indian reservations, police lockups (temporary holding facilities for person who have not been formally charged in court), military stockades and jails, or federal park facilities

    Chart1

    199319931993199319931993

    199419941994199419941994

    199519951995199519951995

    199619961996199619961996

    199719971997199719971997

    199819981998199819981998

    199919991999199919991999

    200020002000200020002000

    200120012001200120012001

    200220022002200220022002

    200320032003200320032003

    200420042004200420042004

    200520052005200520052005

    200620062006200620062006

    200720072007200720072007

    200820082008200820082008

    200920092009200920092009

    201020102010201020102010

    201120112011201120112011

    201220122012201220122012

    201320132013201320132013

    201420142014201420142014

    201520152015201520152015

    201620162016201620162016

    201720172017201720172017

    201820182018201820182018

    Federal Prison

    State Prison

    Local Jail

    Juvenile Correction Facility

    Other*

    Unknown

    Year

    Total No. of Cases

    28

    457

    410

    10

    31

    14

    31

    470

    571

    4

    30

    11

    24

    331

    540

    8

    21

    13

    28

    295

    409

    4

    40

    6

    30

    220

    446

    9

    30

    12

    32

    187

    383

    8

    39

    8

    33

    163

    343

    4

    20

    13

    40

    174

    327

    5

    30

    11

    38

    141

    283

    8

    44

    8

    41

    122

    242

    5

    39

    11

    63

    83

    255

    7

    58

    10

    58

    130

    242

    4

    50

    11

    35

    134

    277

    2

    71

    18

    42

    109

    249

    0

    99

    9

    64

    103

    216

    4

    89

    5

    51

    107

    215

    3

    115

    5

    42

    99

    219

    4

    88

    12

    55

    116

    203

    5

    94

    18

    45

    107

    199

    0

    63

    9

    66

    78

    180

    4

    62

    1

    58

    47

    180

    6

    66

    7

    64

    74

    116

    0

    117

    6

    46

    66

    93

    1

    125

    3

    41

    59

    102

    2

    120

    5

    37

    41

    88

    2

    98

    2

    37

    54

    80

    7

    126

    6

    Sheet1

    Federal PrisonState PrisonLocal JailJuvenile Correction FacilityOther*UnknownColumn1

    199328457410103114950

    199431470571430111117

    19952433154082113937

    1996282954094406782

    19973022044693012747

    1998321873838398657

    19993316334342013576

    20004017432753011587

    2001381412838448522

    20024112224253911460

    2003638325575810476

    20045813024245011495

    20053513427727118537

    2006421092490999508

    2007641032164895481

    20085110721531155496

    2009429921948812464

    20105511620359418491

    2011451071990639423

    201266781804621391

    201358471806667364

    2014647411601176377

    201546669311253334

    2016415910221205329

    20173741882982268

    201837548071266310

    112939676868116176523414079

  • TB Cases Ages ≥15 with Other Selected Risk Factors, 2018

    Risk Factor

    Chart1

    Resident of Long-term Care Facility

    Experiencing homelessness

    Percentage of TB cases

    Column1

    0.017

    0.043

    Sheet1

    SalesColumn1

    Resident of Long-term Care Facility0.017

    Experiencing homelessness0.043

  • Substance Misuse Among TB Patients ≥15 years, United States, 2018

    Chart1

    Injection Drug Use

    Noninjection Drug Use

    Excess Alcohol Use

    Series 1

    Percent of TB patients aged ≥15 years

    0.013

    0.068

    0.093

    Sheet1

    Series 1

    Injection Drug Use1.3%

    Noninjection Drug Use6.8%

    Excess Alcohol Use9.3%

  • Primary Occupation Among U.S. TB Patients Age ≥15 years, 2018

    Perc

    enta

    ge o

    f TB

    Case

    s

    Occupation

    Chart1

    Unemployed

    Retired

    Not Seeking Employment

    Healthcare Worker

    Migrant Worker

    Correctional Employee

    Other

    Series 1

    0.218

    0.18

    0.157

    0.037

    0.012

    0.001

    0.395

    Sheet1

    Series 1

    Unemployed21.8%

    Retired18.0%

    Not Seeking Employment15.7%

    Healthcare Worker3.7%

    Migrant Worker1.2%

    Correctional Employee0.1%

    Other39.5%

  • TB Cases by Reason Therapy Stopped, 2016*

    *Data available through 2016 only.

    Outcomes for patients that did not complete treatment

    Chart1

    Completed Therapy

    Did Not Complete Therapy

    Column1

    []87.2%

    [] []%

    87.2

    12.8

    Sheet1

    Column1

    Completed Therapy87.2

    Did Not Complete Therapy12.8

    Chart1

    Other

    Adverse Event

    Lost to Follow-Up

    Died

    Percent

    0.045

    0.003

    0.013

    0.067

    Sheet1

    Extrapulmonary sitePercent

    Other0.045

    Adverse Event0.003

    Lost to Follow-Up0.013

    Died0.067

  • Deaths Attributed to TB Disease or TB Treatment, 2016*9 of every 100 TB patients diagnosed in 2016 died

    before diagnosis or during treatmentMore than 3 of the 9

    deaths were attributed to TB disease or TB treatment

    *Data available through 2016 only.

  • Sputum Culture Conversion, United States, 2016

    Chart1

    Documented

    Not Documented

    Column1

    []82.4%

    [] []%

    82.4

    15.8

    Sheet1

    Column1

    Documented82.4

    Not Documented15.8

    Chart1

    Unknown

    Other

    Refused

    Lost to follow-up

    Could Not Produce

    Sputum Not Collected

    Died

    Percent

    0.368

    0.108

    0.004

    0.026

    0.048

    0.143

    0.303

    Sheet1

    Reasons not ConvertingPercent

    Unknown0.368

    Other0.108

    Refused0.004

    Lost to follow-up0.026

    Could Not Produce0.048

    Sputum Not Collected0.143

    Died0.303

  • National Tuberculosis Genotyping Surveillance Coverage* by Year: United States†, 2004–2018

    * The proportion of positive cultures with at least one genotyped isolate.† Includes 50 states and the District of Columbia.§ For the year 2020, the national goal for TB genotyping surveillance coverage will change to 100%.

    National Goal, 94%§

    Chart1

    20042004

    20052005

    20062006

    20072007

    20082008

    20092009

    20102010

    20112011

    20122012

    20132013

    20142014

    20152015

    20162016

    20172017

    20182018

    Coverage (%)

    National Goal

    Proportion of culture confirmed TB cases genotyped (%)

    52.6

    94

    68.4

    94

    70.1

    94

    80.8

    94

    81.6

    94

    86.9

    94

    91.6

    94

    94.2

    94

    94.9

    94

    95.9

    94

    96.7

    94

    97.1

    94

    97.4

    94

    97.4

    94

    96.3

    94

    Sheet1

    Coverage (%)National Goal

    200452.694

    200568.494

    200670.194

    200780.894

    200881.694

    200986.994

    201091.694

    201194.294

    201294.994

    201395.994

    201496.794

    201597.194

    201697.494

    201797.494

    201896.394

  • Definition for Tuberculosis Genotypingin the United States

    Initial 12-locus MIRU-VNTR1: 223325173533

    Spoligotype: 000000000003771

    PCRType:PCR00002

    Additional 12-locus MIRU-VNTR (MIRU2): 4445344234282

    +

    GENType:G00010

    Sequentially assigned for each unique spoligotype and initial 12-locus MIRU-VNTR combination

    Sequentially assigned for each unique spoligotype and 24-locus MIRU-VNTR combination

    1 Mycobacterial interspersed repetitive unit–variable number tandem repeat.2 The complete set of 24 loci is referred to as 24-locus MIRU-VNTR and is used for GENType designation for genotype in the United States.

  • Number of County-based Tuberculosis Genotype Clusters* by Cluster Size, United States, 2016–2018

    *Genotype cluster is defined as two or more cases with matching spoligotype and 24-locus MIRU-VNTR (GENType) within a county during the specified 3-year time period.

    Chart1

    2 case cluster

    3 case cluster

    4 case cluster

    5 case cluster

    6 case cluster

    7 case cluster

    8 case cluster

    9 case cluster

    ≥10 case cluster

    Number of clusters

    Number of Persons in Cluster

    Number of clusters

    893

    224

    90

    42

    33

    21

    5

    12

    29

    Sheet1

    Number of Persons in ClusterNumber of clusters

    2 case cluster893

    3 case cluster224

    4 case cluster90

    5 case cluster42

    6 case cluster33

    7 case cluster21

    8 case cluster5

    9 case cluster12

    ≥10 case cluster29

  • Tuberculosis Genotype Clusters by TB GIMS* Alert Levels†, United States, 2016–2018

    *Tuberculosis Genotyping Information Management System†Alert level is determined by the log likelihood ratio statistic (LLR) for a given cluster, identifying higher than expected geospatial concentrations for a TB genotype cluster in a specific county, compared to the national distribution of that genotype; TB GIMS generates alert level notifications based on this statistic: “No alert” is indicated if LLR is between 0 –

  • Genotyped Tuberculosis Cases Estimated to be Attributed to Recent Transmission, United States, 2017–2018

    Recent Transmission*12.6% (n=1,712)

    Not Recent Transmission§

    (n=11,889)

    8.3% (n=1,123)

    4.3% (n=589)Limited Recent Transmission

    Extensive Recent Transmission†

    * A TB case is designated as attributed to recent transmission if a plausible source case can be identified in a person who i) has the same M. tuberculosis genotype, ii) has an infectious form of TB disease, iii) resides within 10 miles of the TB case, iv) is 10 years of age or older, and v) was diagnosed within 2 years before the TB case.† A TB case is designated as attributed to extensive recent transmission when the criteria above for recent transmission are met, and furthermore the case belongs to a plausible transmission chain of six or more cases. Otherwise, the case is designated as attributed to limited recent transmission.§ Cases not attributed to recent transmission may be misclassified in children

  • Genotyped Cases Estimated to be Attributed to Limited and Extensive Recent Transmission, United States, 2015–2018

    n=1,712

    * A TB case is designated as attributed to recent transmission if a plausible source case can be identified in a person who i) has the same M. tuberculosis genotype, ii) has an infectious form of TB disease, iii) resides within 10 miles of the TB case, iv) is 10 years of age or older, and v) was diagnosed within 2 years before the TB case.† A TB case is designated as attributed to extensive recent transmission when the criteria above for recent transmission are met, and furthermore the case belongs to a plausible transmission chain of six or more cases. Otherwise, the case is designated as attributed to limited recent transmission.

    Chart1

    2015–20162015–2016

    2017–20182017–2018

    n=1,894

    Extensive Recent Transmission†

    Limited Recent Transmission

    Cases Attributed toRecent Transmission*

    n=690 (36.4%)

    n=[](34.4%)

    n=[](63.6%)

    n=[](65.6%)

    690

    1204

    589

    1123

    Sheet1

    Extensive Recent Transmission†Limited Recent Transmission

    2015–20166901,204

    2017–20185891,123

  • Percentages of Tuberculosis Cases Estimated to be Attributed and Not Attributed to Recent Transmission, by Origin of Birth*, 2017–2018

    * Cases with unknown origin of birth not shown (n=21).† A TB case is designated as attributed to recent transmission if a plausible source case can be identified in a person who i) has the same M. tuberculosisgenotype, ii) has an infectious form of TB disease, iii) resides within 10 miles of the TB case, iv) is 10 years of age or older, and v) was diagnosed within 2 years before the TB case.§ Cases not attributed to recent transmission may be misclassified in children

  • The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

    Division of Tuberculosis Elimination National Center for HIV/AIDS, Viral Hepatitis, STD, and TB PreventionCenters for Disease Control and Prevention 1600 Clifton Road NEUS 12-4Atlanta, GA 30329Phone: 404-639-8120Internet Address: http://www.cdc.gov/tb/

    http://www.cdc.gov/tb/

    Tuberculosis in the United States�1993–2018*�Reported Tuberculosis (TB) Cases and Rates �United States, 1993–2018Total TB Case Rates and�Annual Percent Change in Rate, 2010–2018 Reported Tuberculosis (TB) Deaths* and Rates �United States, 1993–2017Percentage of TB Cases by State, United States, 2018Slide Number 6Map of U.S.-Affiliated Pacific Islands and Hawaii�by TB Case Rates*, 2018TB Cases and Rates Among U.S.-Born versus �Non-U.S.–Born Persons, United States, 1993–2018Countries of Birth Among Non-U.S.–Born Persons Reported with TB, United States, 2018*TB Rates for Top 10 Countries of Birth*�United States, 2014–2018Percentage of Non-US–Born TB Cases�by Time in the United States at Diagnosis, 2018Reported TB Cases by Race/Ethnicity,*�United States, 2010–2018TB Case Rates by Race/Ethnicity,* �United States, 2010–2018Reported TB Cases by Origin and Race/Ethnicity*, United States, 2018†Reported TB Cases by Age Group, �United States, 1993–2018TB Case Rates by Age Group, �United States, 1993–2018Distribution of Sex by Age Group, �United States, 2018��Pediatric TB Cases by Age Group, 1993–2018�Number of U.S. Pediatric TB Cases among U.S.-Born and Non-U.S.–Born* Children, 1993–2018Number of U.S. Pediatric TB Cases among U.S.-Born Children by Parent/Guardian Status, 2010–2018Number of U.S. TB Cases by Case Verification Criteria, 1993–2018U.S. TB Cases by Site of Disease, 2018Percentage of Tuberculosis Cases*, by Initial Drug Regimen, United States, 1993–2018Mode of Treatment Administration Among Persons Reported with TB, United States, 1993–2016*Completion of TB Therapy,�United States, 1993–2016*Isoniazid Resistance Among U.S.-Born versus Non-U.S.–Born Persons, United States, 1993–2018Cases of MDR TB* by History of TB, United States, 1993–2018HIV Coinfection by Age Among Persons �Reported with TB, United States, 2011–2018Reported TB Case Percentages* by Risk Factor, United States, 2018TB Cases among Residents of Correctional Facilities Ages ≥15, 1993–2018*TB Cases among Residents of Correctional Facilities Ages ≥15 by Type of Facility, 2010–2018TB Cases Ages ≥15 with Other Selected Risk Factors, 2018Substance Misuse Among TB Patients ≥15 years, United States, 2018 Primary Occupation Among U.S. TB Patients Age ≥15 years, 2018 TB Cases by Reason Therapy Stopped, 2016*Deaths Attributed to TB Disease or TB Treatment, 2016*Sputum Culture Conversion, United States, 2016National Tuberculosis Genotyping Surveillance Coverage* by Year: United States†, 2004–2018Definition for Tuberculosis Genotyping�in the United StatesNumber of County-based Tuberculosis Genotype Clusters* by Cluster Size, United States, 2016–2018Tuberculosis Genotype Clusters by TB GIMS* Alert Levels†, United States, 2016–2018Genotyped Tuberculosis Cases Estimated to be Attributed to Recent Transmission, United States, 2017–2018Genotyped Cases Estimated to be Attributed to Limited and Extensive Recent Transmission, United States, 2015–2018Percentages of Tuberculosis Cases Estimated to be Attributed and Not Attributed to Recent Transmission, by Origin of Birth*, 2017–2018Slide Number 45