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......................................................................................................................47Natural astaxanthin from a strain of algae
he Indian pharmaceutical industry may have to common man. Simultaneously, the NPPA, too, of late, has
brace itself for stricter price regulations. The taken some stringent steps in the direction. For instance,
Central Government is embarking on a legislation for the first time, the regulator has attempted to cap the Tthat would be akin to the pricing models that are existing launch price of medicines. In a recent notification, the
across the US, European Union (EU), China and 14 regulator said prices of new brands of existing medicines
Organisation for Economic Co-operation and will have to be at par with the most expensive drug in the
Development (OECD) countries. The National segment. In another such notification, using a public
Pharmaceutical Pricing Authority (NPPA), which regulates interest provision in the DPCO, 2013, the regulator has
prices of medicines in the market, has already initiated said it would monitor the difference in prices between
work in that direction. It is learnt that the agency plans to various brands of medicines used in treatment of cancer,
come up with the first draft of the legislation by the end HIV, tuberculosis, malaria, cardiovascular diseases,
of this financial year. The agency have begun dialogue diabetes and asthma. Companies evade the price ceiling
with certain institutions to commission a study that by the simple trick of adding or changing one or more
would look into pricing models of different countries. It is ingredients in a price-controlled drug. Some of the
also internally exploring areas which can be of examples of such manipulation, already done in the past,
significance like focus of the study and terms of include Aciloc-RD of J Chemicals (where the price-
reference etc. The study is expected to be formally controlled ranitidine was replaced with omeprazole);
commissioned in the next three months. It is further Cetrizet-D of Sun Pharmaceutical (price-controlled
learnt that the proposed legislation will cover all kind of pseudoephedrine replaced with phenylepherine), Normet
medicines including patented, imported and even non- of Emcure (price-controlled norfloxacin replaced with
scheduled drugs. Currently, the prices of medicines are ofloxacin) and Brakke Suspension of Franco-Indian
regulated under the Drug Price Control Order (DPCO), Pharmaceuticals (price-controlled ciprofloxacin replaced
2013, emerging out of the National Pharmaceutical with ofloxacin). The brand name was never changed in
Pricing Policy, which was cleared by the previous the above-mentioned cases. One of the means to keep
government. Also, the proposed legislation would provide the prices under control would be that all combination
more teeth to NPPA, enabling it to penalize companies drugs, patented drugs, life saving drugs and molecules in
flouting the law or overcharging consumers for the same therapeutic class be brought under price
medicines. An Act is much superior instrument to merely control. As a matter of fact, Para 32 of the DPCO 2013
rule-making power. The agency is looking at moving lists cases eligible for exemption from price regulation for
towards a progressive legislation based on international five years: drugs that have a product/process patent in
models, which will be reasonable while providing more India and “new drugs” as per Rule 122E of the Drugs and
powers to NPPA to keep a check on prices. Cosmetics Rules, 1945 with the proviso that such drugs
Currently, the Indian pharmaceutical market is be developed through indigenous research and
worth around Rs 79,000-crore. Of this, around 30 per development (R&D). The other provision for exemption for
cent is under regulation. As a result, the prices of 348 new indications and new dosages and new delivery
essential medicines are capped at the average of all systems (under Rule 122E) would only increase frivolous
drugs in a particular segment with more than one per claims for new indications/new non-standard dosages
cent market share. Prices of these medicines are allowed and/or result in existing simple tablets. For instance,
an annual hike based on Wholesale Price Index. For all being put unnecessarily in a sustained release form –
other medicines, companies are free to raise prices up to which will then be a “new drug” under 122E and
10 per cent annually. The Narendra Modi government at therefore price control exempt. Thus there is an urgent
the Centre is expected to keep a stringent check on need to have a good system to assess such claims by
prices of medicines and make them affordable for the manufacturers.
CONTROL THE PRICING MECHANISM
EDITORIAL
22 THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l
CC Chemipack CorporationA/702, 7th Floor, Winsway Complex, Old Police Lane, Andheri (E), Mumbai - 400 069.
Dr Deepak Parikh, vice per cent of patients, as compared CLARIANT OPENS NEW chairman and managing director, to 60 per cent of patients who INDIA HEADQUARTERS Clariant Chemicals (India) further respond to other medical
AT AIROLI, MUMBAIinformed that 2014 is a year of treatments such as corticosteroids
Mumbai : Clariant Chemicals transformation for Clariant in India, and phototherapy. The studies have
(India), one of the leading specialty and as they continue to grow, it is also shown that patients respond
chemicals producer of India, important that their facilities reflect faster when Melgain lotion is used
recently opened its new state-of-the-and act as enablers for their in combination with other medical
art headquarters at Reliable Tech commitment to innovation and fleet- treatments options. Vitiligo is a skin
Park in Airoli, Navi Mumbai. The footed customer services. “It will be disease that leads to white patches
inauguration of this facility is in line our endeavour to utilise this facility on the body due to the loss of
with the company's plan for to its full potential and drive normal skin pigment called melanin.
increased growth through greater Clariant into a new era of prosperity It is a very common disease that
focus on innovation and profitable and success,” said Dr Parikh. affects all races, and is estimated
growth. The new office reinforces to affect about 5 crore people in DR REDDY'S Clariant's commitment to growth India. Vitiligo leads to emotional LAUNCHES MELGAIN through focus on technology and distress as the disease affects the
FOR TREATMENT OF greater efficiency. It will allow the appearance of the patient. As white
company to expand its capacity, VITILIGO patches are more obvious on generate value and greater service Mumbai : Dr Reddy's Laboratories, generally dark Indian skin, the satisfaction to its customers. The an integrated global pharma condition is socially stigmatised. In new headquarters have been company, announced the launch of a study, 54.5 per cent patients designed to act as a catalyst for the Melgain, lotion that has been suffering from vitiligo were found to envisioned growth of the company's approved for the treatment of be depressed. On an average, an operations in India. vitiligo, to benefit patients of the Indian dermatologist who treats Dr Hariolf Kottmann, CEO, skin pigmentation disorder in India. Vitiligo sees 20 patients in a Clariant International said, “The The medication has been launched month. Melgain lotion's unique future of Clariant is in Asia – and in partnership with Issar mechanism of action enhances re-India is a key market for Clariant Pharmaceuticals to increase pigmentation when used in globally. I am excited to open a new access to a novel treatment for combination with other therapies. chapter for Clariant in the country vitiligo patients in India. Globally, To ensure that the active drug with the new headquarters in Navi Melgain lotion (decapeptide) is the penetrates the skin, Melgain lotion Mumbai. The new office will afford first peptide-based drug for the has been fortified with skin us the opportunity to broaden our treatment of vitiligo. It has been penetration enhancers, leading to customer base, deliver innovative indigenously developed in India. optimal outcomes. Melgain is Dr solutions and create value that will Melgain lotion is the only patented Reddy's attempt to support vitiligo benefit all our stakeholders. We decapeptide derived from basic patients in overcoming the disease, intend to improve our market fibroblast growth factor, a regaining skin color and reducing presence and generate additional substance the body naturally associated emotional distress.growth through a sustained thrust produces for maintaining the NOVO NORDISK TO on innovation.” structure and function of melanin
HIRE 6,000 NEW The new facility covers a total producing cells. Melgain lotion is EMPLOYEES IN area of 140,000 sq feet will safe and efficacious in vitiligo
eventually house around 400 DENMARK BY 2022cases involving various areas of the employees across the various body, as established by a number Bagsværd : Novo Nordisk, a global service functions and the of clinical studies. Its safety is well healthcare company with more than businesses of pigments, additives, established for treating children as 90 years of innovation and industrial and consumer well. leadership in diabetes care, to hire specialties, masterbatches, and Melgain lotion leads to re- 6,000 new employees in Denmark also their technical service teams. pigmentation in 80 per cent to 90 by 2022, half of whom will work
PHARMACEUTICAL NEWS
32 THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l
within research and development. lack of standardization. The industry GENE EXPRESSION The new jobs will have the derived should focus on creating a standard PROFILING DRIVES effect of boosting employment by platform for gene expression
PERSONALIZED more than 15,000 jobs nationally. profiling scoring high on accuracy,
MEDICINE This is revealed by a new analysis sensitivity, and performance. In WORLDWIDEpresented by Novo Nordisk at the addition, the industry must invest in
London : Gene expression profiling 'Invitation to growth - a road to job more clinical trials to enhance the can bring significant improvements creation' conference. The analysis credibility of gene expression to disease profiling and diagnoses homes in on the value created in profiling tests and create based on genetic disposition. the interaction between growth standardized protocols to enable life Recent technology advances in this businesses and public-sector science firms to conduct clinical area are in fact enabling research and education, as well as trials across developer platforms.personalized medicine, where the challenges that must be solved Having tight protocols in physicians provide patients with so that research-based businesses place will also support the tailor-made treatment plans to fight can continue to grow in Denmark. development of data storage, diseases. Cases of cancer, "With the expectation of creating management, and visualization cardiovascular diseases, and 6,000 new jobs in Denmark over platforms. These platforms will be neurological disorders stand to the coming years, it will be crucial necessary as the declining costs of benefit the most from these for Novo Nordisk that Denmark next generation sequencing (NGS) developments, since these educates world-class graduates but lead to a boom in raw genetic data conditions manifest differently in also focuses far more intently on production. Large investments are each patient.attracting international talent," already taking place across the New analysis from Frost & says executive vice president and industry, with life science firms Sullivan, Advances in Gene chief science officer Mads actively trying to enter the software Expression Profiling, finds that Krogsgaard Thomsen. The analysis world and software players looking gene expression profiling presents new forecasts for the to capture start-up genetic profiling technology has established a future availability of university companies. Cloud-based data tools presence in North America and graduates and PhDs and questions for accessing genomic information most of Europe. Emerging markets, whether Denmark is investing will prove particularly useful in on the other hand, include India, sufficiently in the frameworks that related industries including China, South Korea and Australia.are necessary for providing strong pharmacogenomics and oncology “Physicians increasingly rely on research-based degree diagnostics.gene expression profiling to get a programmes. “Gene expression profiling thorough picture of the patient's The conference is being will continue to grow rapidly over the genetic profile prior to arriving at a hosted by Novo Nordisk at the next five years as consumer diagnosis and recommending a company's headquarters in awareness grows,” stated Rangesa. course of treatment,” noted Bagsværd. The debaters will “In fact, gene expression profiling Technical Insights Research include Danish Minister for Higher will become a crucial aspect across Analyst Madhumitha Rangesa. Education and Science Sofie pharmacogenomics, direct to “With multiple disease diagnostic Carsten Nielsen; Chair of the consumer genetic testing and tests currently undergoing clinical Government's Expert Committee on academic research.”trials and approval procedures, Quality in Higher Education Jørgen Frost & Sullivan, the Growth patients will soon have access to Søndergaard; Rector of the Partnership Company, works in interpretable genetic profiles – a University of Copenhagen Ralf collaboration with clients to leverage definite way to boost patient Hemmingsen; and the political visionary innovation that addresses awareness and encourage spokespersons for the Liberal Party the global challenges and related preventative care.” However, of Denmark and the Danish Social growth opportunities that will make regulatory barriers pose a huge Democrats. or break today's market challenge for providers and life participants. science firms, mainly due to the
PHARMACEUTICAL NEWS
THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l 33
PRESS RELEASE
outh India, especially Chennai and Puducherry are BIG manufacturers of Pharmaceutical, Neutraceutical as well as Herbal and Veterinary formulations. Thus Screating a need for a platform that brings to these manufacturers business
opportunities in their very own land. After the roaring success of Pharmac India, Orbit Exhibitions Pvt. Ltd. and Indian Drug Manufacturers Association (IDMA-TNPSB) present PHARMAC SOUTH 2014 – A unique event that will gear up the Southern Pharmaceutical industry with more bandwidth and action. Pharmac South is a 3 day event that will be held from 27th, 28th and 29th June 2014 in Chennai, India. This mega event will essentially platform Contract Manufacturers, Pharmaceuticals, Nutraceuticals, Herbal, Veterinary Formulations, and more in the Medical & Pharmaceutical industry. Pharmac South 2014 will be a platform to procure more information, network, have one-to-one-meetings, strike big deals and explore new horizons for the Southern manufacturers with both domestic and international visitors. So, join in. It is opportunities calling.
For details and participate, contact Orbit Exhibitions Pvt. Ltd. Tel: 022-24102801/2/3 Cell: 09322037955 E-mail: [email protected]
he international exposure through this exhibition will may provide more opportunities and provide latest information to all the stakeholders”, expressed Shri Narendra Modi T– Chief Minister, Gujarat State.
Such is the potential that PHARMAC INDIA holds in the pharmaceutical arena. Now, Pharmac India 2014 is poised to be bigger, better and even more opportunity driven than its previous editions. Jointly organized by Orbit Exhibitions Pvt. Ltd. & Indian Drug Manufacturers' Association (IDMA-GSB), Pharmac India 2014 endeavours to bring together manufacturers, suppliers, dealers, international brands and quality visitors, under one roof. Needless to mention, its past editions have successfully brought together manufacturers and buyers on a common platform and contributed substantially towards the growth of the industry. This 5th Edition will be held on 11th, 12th and 13th September 2014 at Mahatma Mandir, Gandhinagar, India; and have a special focus on Machinery, Equipment, Bulk Drugs, API, Pharma Lab, Pharma Pack & Material in addition to Pharma Contract Manufacturers, Clean room & Water Technology Exhibition in India. So imagine the excitement, the frenzy and the opportunities.
Pharmac India 2014. It is one exhibition you can't afford to miss. For details and participate, contact Orbit Exhibitions Pvt. Ltd.
laxoSmithKline announced weeks and months. The start of include those which examine
the start of a pivotal phase our losmapimod study is an hospitalisation for heart failure and GIII study, LATITUDE-TIMI 60, important step forward in the stroke.
to evaluate the effects of search for innovative therapies The LATITUDE-TIMI 60 study
losmapimod in patients presenting aimed at reducing the recurrence is being conducted in collaboration
with acute coronary syndrome of cardiovascular events.” with the TIMI Study Group, Brigham
(ACS). The global, phase III study LATITUDE-TIMI 60 and Women's Hospital, Boston,
will assess whether losmapimod (LosmApimod To Inhibit p38 MAP Massachusetts.
can reduce the risk of a kinase as aTherapeUtic target and Losmapimod is an anti-
subsequent cardiac event when moDify outcomes after an acute inflammatory that works by
administered orally twice a day for coronary syndrome-Thrombolysis In inhibiting the activity of p38, a
a period of three months Myocardial Infarction 60; mitogen-activated protein kinase,
immediately after presentation with NCT02145468) is a randomised, which is a type of enzyme that is
an acute coronary syndrome. Acute double-blind, placebo-controlled, associated with the acute
coronary syndrome is a term used multi-centre study across 39 inflammation that occurs in the
to describe situations or events, countries. It is anticipated that a blood vessels during and
including heart attack, where there total of 25,500 patients will be immediately after an acute coronary
is an abrupt reduction of blood flow enrolled over the study period. syndrome. For cardiovascular
to the heart through the coronary Eligible patients presenting with disease, studies have
arteries. Presentation by a patient acute coronary syndrome demonstrated several key biological
with acute coronary syndrome is a (specifically, a heart attack) will be functions of p38 MAP kinase in the
manifestation of coronary heart randomised to receive three coronary vessel wall and in the
disease. Losmapimod is an months of twice daily oral myocardium, which make p38 MAP
inhibitor of p38 mitogen activated treatment with either 7.5mg of kinase inhibition a potentially
protein (MAP) kinase, an enzyme losmapimod or placebo in addition important therapeutic approach in
understood to play a central role in to standard of care. acute coronary syndrome. Evidence
the acute inflammation that occurs The primary efficacy endpoint to date suggests that p38 MAP
during a heart attack. of the study is the composite kinase inhibition may potentially
Dr. John Lepore, senior vice measure of adjudicated major attenuate the inflammatory
president of Metabolic Pathways adverse cardiovascular events, processes in the vascular wall,
and Cardiovascular R&D at GSK, comprising the time to first improve vascular function and
commented:“Although changes in occurrence of cardiovascular prevent subsequent thrombosis,
diet and lifestyle along with new death, myocardial infarction, or thereby potentially reducing the risk
approaches to treatment have led severe recurrent ischemia requiring of subsequent plaque rupture and
to improved outcomes for patients urgent coronary artery cardiac events. Losmapimod is
with coronary artery disease, revascularisation. The key designed as a short-term treatment
patients who suffer a heart attack secondary endpoint of the trial is to be administered as quickly as
remain at increased risk of a cardiovascular death and possible after an acute coronary
recurrent heart attack or other myocardial infarction. Other syndrome (specifically, a heart
vascular event in the ensuing composite secondary endpoints attack) and for a period of 12
PHARMACEUTICAL ARTICLE
PHASE III STUDY OF LOSMAPIMOD IN PATIENTS WITH ACUTE CORONARY SYNDROME
THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l 35
weeks thereafter, when the patient function mutations and is placebo for two, two-week treatment
is most at risk of a further major supported by in vitro observations cycles as part of a multiple within-
cardiovascular event. that showed ivacaftor enhanced the patient crossover design. In the first
POSITIVE RESULTS FROM PROOF- function of the cystic fibrosis treatment cycle of part one, patients
transmembrane conductance received either ivacaftor or placebo OF-CONCEPT STUDY OF
regulator (CFTR) protein in cells for two weeks, which was IVACAFTOR WITH CF PATIENTS
with residual function mutations. immediately followed by the WHO HAVE RESIDUAL FUNCTION
Based on these data, Vertex plans opposite treatment (placebo or MUTATION : Vertex
to initiate a larger Phase 3 study in ivacaftor) for two weeks. The Pharmaceuticals Incorporated, a
people with residual function treatment cycles were separated by global biotechnology company that
mutations that will evaluate longer- a four-week washout period, and in aims to discover, develop and
duration treatment with ivacaftor, the second treatment cycle of part commercialize innovative
pending discussions with regulatory one, patients received either medicines, announced the results
authorities. ivacaftor or placebo for two weeks, of a two-part proof-of-concept study
There are more than 3,000 immediately followed by the of ivacaftor in 24 people with cystic
people ages 6 and older in North opposite treatment (placebo or fibrosis (CF) who have a residual
America, Europe and Australia who ivacaftor) for two weeks. Part two of function mutation.
have a non-R117H residual function the study, the open-label evaluation, The first part of the study
mutation. was separated from the second evaluated ivacaftor, compared with
"This study showed potential treatment cycle by a four-week placebo, in a two-week crossover
for ivacaftor to provide clinical washout period, and all patients design over two treatment cycles,
benefit for many of the people who received ivacaftor in this part of the and the second part of the study
have a residual function mutation study.evaluated ivacaftor in an eight-week
and provides important support for The primary endpoint analysis open-label design. In part one, a
the initiation of a Phase 3 study in was based on part one of the study statistically significant improvement
people with these mutations," said and evaluated the mean absolute in mean absolute lung function
Jeffrey Chodakewitz, managing change from baseline in lung (percent predicted forced expiratory
direcrtor, senior vice president and function (percent predicted forced volume in one second; PPFEV1)
chief medical officer at Vertex. expiratory volume in one second; was observed after treatment with
"While this was a small proof-of- PPFEV1) at the end of two weeks of ivacaftor for two weeks compared
concept study, these data are treatment versus placebo. The study with placebo.
another step forward in our enrolled 24 people age 12 and In part two of the study,
commitment to expand the number older with a residual function improvements in lung function
of people who can benefit from mutation. All people with a residual (PPFEV1) were observed after eight
ivacaftor." function mutation have some weeks of treatment. In the study,
The first part of the study functioning CFTR protein. Depending ivacaftor was generally well-
included two randomised, double- on the specific mutation, residual tolerated, and the most common
blind, placebo-controlled treatment function mutations can result in adverse events in the treatment
cycles (part one), and the second defective CFTR proteins at the cell group were cough and respiratory
part of the study was an eight-week surface and/or a reduced number of tract infection.
open-label period (part two). In part CFTR proteins at the cell surface. This proof-of-concept study
one, patients received ivacaftor for was the first to evaluate the use of
two, two-week treatment cycles and ivacaftor in multiple residual
IN-SIGHT 7010 AND 7010Cn-Sight® 7010 from COGNEX is an entry-level smart camera vision system developed specifically for inspection
tasks where vision sensors are too limited and the solutions available in the market may not be cost effective or Imay not suit the entire requirements. With the unique combination of hardware features and software tools, the In-
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The Easybuilder software helps the user to quickly set up their application without programming knowledge.
Included in this are tools such as Pattern Matching, Edge, Blob, and Circle detection tools. Additionally, the color
vision system model includes a Color ID tool for applications that require the ability to identify different colors. It has
800 x 600 (SVGA) resolution and takes 102 frames per second. It has an external light connector providing powers
and strobe (requires Cognex light cable kit).
In-Sight 7010 has an integrated
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It also offer integrated, field-replaceable white lighting as well as four specific color lights (red, green, blue
and Infrared) to highlight particular parts or features. The compact In-Sight 7010 features integrated white lighting
that is suitable for most vision applications. If a specific color light is required to highlight particular parts or features,
four optional colored lights are available. The autofocus optics and integrated lighting developed for the In-Sight 7010
are also being deployed as options across the full In-Sight 7000 product range.
Proven Software Tools :
In-Sight 7010 features EasyBuilder and a selection of the key inspection, measurement, alignment and guidance
vision tools found on other In-Sight vision systems. With the unique combination of hardware features and software
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Entry-level Model Options:? In-Sight 7010 base model has an image capture rate of 102FPS at 800x600 resolution. The basic tool set includes 360° degree pattern matching, edge, blob, circle, histogram, math and basic geometry tools.? In-Sight 7010C color model has an image capture rate of 50FPS at 800x600 resolution. The tool set is enhanced with a Color ID tool for setting up inspection jobs where color is the differentiating feature.
Key features of In-Sight 7010 and 7010C:
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New Product Launch?Stabilized Bromine (Bromine Additive 10%)
Biocide For Cooling Water Treatment Bromine ChemistryRepresents Cost-effective Oxidizing Microbial Control EspeciallyIn Alkaline Waters And Where Nitrogen Compounds May BePresent As A Contaminant In The Cooling Water Stream.
harmachem Laboratories developed two market-ready investor InterWest Partners, with all
division Avoca announced products from heterotrophic and existing major investors
that it has signed into a phototropic algae sources. The participating. Silicon Valley Bank Psupply agreement with Synthetic company has also demonstrated was the sole debt provider,
Genomics (SGI) for the extraction commercial-scale manufacturing according to a Benvenue
and marketing of natural capability and performance of the announcement.
astaxanthin from a strain of algae substance over the course of 18 Under the leadership of CEO
developed by SGI's Genovia Bio months. Robert Weigle, Benvenue has
business unit. Under the terms of Jon Getzinger, SVP of raised a total of $85.5 million since
the multi-year supply agreement, Synthetic Genomics, said that the the company was founded, the
Avoca will gain exclusive rights to company is pleased to partner with Silicon Valley Business Journal
product sales in North America. Pharmachem Labs and Avoca. “Our reported.
Pharmachem Lab alone will be ability to develop advantaged “We welcome new investor
responsible for marketing and nutraceutical and human and InterWest Partners, and we're
sales. According to David Peele, animal feed ingredients coupled gratified by the continued support
President of Avoca, “This with Avoca's ability to process and from our existing investors and
agreement will make us one of just market those products, makes this Silicon Valley Bank, who has been
a handful of vertically integrated, an ideal agreement for both our long-standing banking partner,
domestic producers of astaxanthin, companies. Commercialization of Weigle said.
with SGI providing sufficient algae astaxanthin with Avoca The medical device maker
biomass to ensure our customers demonstrates how we can supply entered the spine device market
of a consistent supply from U.S. important high quality, natural with three minimally invasive
sources. Using their proprietary ingredients to the market using our products to treat degenerative disc
technology, SGI has developed algae technology.” No financial disease, including:
algae with a higher level of details of the supply agreement * Kiva VCF Treatment System to
astaxanthin, and as a result, we between the two companies were provide implant-based approach to
can provide 7.5% astaxanthin disclosed. vertebral augmentation for painful
SPINE REPAIR DEVICE : Benvenue oleoresin with the concentration VCFs.
Medical, a developer of minimally increasing over time as the algae * Blazer- C Vertebral Augmentation
invasive solutions for spine repair, strain and production technology is System, which is used by
has raised $64 million to build its improved.” physicians to create channels
U.S. commercial presence and Natural astaxanthin is a within the vertebral body for bone
scale up manufacturing of its supplement that offers powerful cement delivery.
spinal implant, as well as fund antioxidant and anti-inflammatory * Luna Interbody System, which
overall corporate growth activities.properties for health benefits. The incorporates Benvenue Medical's
The financing is a substance is difficult to produce proprietary implant technology, is
combination of $40 million in and available in limited supply. SGI used in minimally invasive spinal
Series E equity supplemented with has developed a production process fusion procedures for degenerative
$24 million in debt. The Series E for natural astaxanthin from a disc disease.
equity financing was led by new phototropic source. Genovia Bio has Weigle added that they
MACHINERY ARTICLE
47THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l
believe the large investment in Ben the drone concept and Ziering has statement of GLP from the Belgium
Venue is due to the successful US stated that he is open to partnering Scientific Institute of Public Health
launch of Kiva, as well as Luna's CE with pharmacies or investors that on behalf of the Organization for
mark and its upcoming FDA are interested. Still, QuiQui needs Economic Cooperation and
submission. to get regulatory approval by the Development (OECD). The Belgium
DRONE FOR DELIVERING DRUGS Federal Aviation Administration GLP Monitorate conducted three
before any drones can deliver GLP inspections, which the facility TO PATIENTS : QuiQui, a start-up
pharmaceutical products. Privately successfully passed.company based out of San
owned drones have to maintain a “The Belgian GLP statement Francisco, is creating early
distance of 500 feet from densely for our toxicology facility is a further prototype drones for the purpose of
populated areas and steer clear of acknowledgment of the quality of delivering drugs to patients. Using
airports. our services, which meet the drone technology to deliver
TOXICOLOGY FACILITY PASSES highest international standards. pharmaceutical drugs is a
With this recognition, WuXi has fascinating concept that founder FDA GLP INSPECTION : WuXi
further solidified its leadership in Josh Ziering believes will ultimately PharmaTech, a pharmaceutical,
offering the highest-quality benefit patients, retailers, and biotechnology, and medical device
toxicology service in China. pharmaceutical companies. Ziering R&D services company operating in
Toxicology is an important part of commented on his company and China and the U.S., announced that
WuXi's comprehensive, fully drone technology. “You have a its Suzho-located toxicology facility
integrated platform of services for headache because you were up late passed Good Laboratory Practice
our global and domestic last night and you need an Advil. (GLP) inspection by the U.S. Food
pharmaceutical and biotech Open up your phone, and just like and Drug Administration (FDA). The
clients,” said Dr. Ge Li. GLP is a your favorite car-sharing application company said the inspection was
quality system that assesses the or taxi application, you're going to the first of its kind in the toxicology
organizational processes and drop a pin on a place....You'll put in facility's five years of operation.
conditions under which health your order, one of our technicians The FDA surveyed the site for five
safety studies are planned, will get your order, and we'll attach days and reviewed numerous
performed, monitored, recorded, it to the drone.” processes as well as the audit of
archived, and reported in a facility. Ziering adds that he envisions four studies. The company's
Earlier this year, the company his company's drones being able to Suzhou toxicology facility has
also announced the construction of deliver necessary medication to completed more than 90
a new biosafety testing facility in people living in the San Francisco Investigational New Drug (IND)
Suzhou. The facility consists of area 8-12 minutes after they've enabling programs for worldwide
38,000 sq ft of laboratories and placed an order. Once an order is regulatory filing. Dr. Ge Li,
support areas in a building adjacent complete and the drone has arrived, Chairman and CEO of WuXi
to the company's GLP preclinical users will get a notification on their PharmaTech, said, “The outcome of
drug safety facility. The site's mobile device. "You'll swipe to the FDA inspection further
service offerings will include viral drop," Ziering says. "And as soon demonstrates the consistency of
clearance testing and as you swipe, the drone will receive our GLP compliance and quality
virus/molecular-based safety that information, drop your order services following the excellent
detection services for both Chinese with a streamer, and away you go." results of earlier OECD and CFDA
and multinational customers.QuiQui is currently looking to raise inspections.” The Suzhou
money in order to further develop toxicology site has also received a
awmakers were briefed current food safety regulations to cases continuing to emerge. The
Monday in Beijing by the make sure offenders face harsh company has not issued a recall for Lhead of the country's food civil, administrative and criminal any of its products. The US Centers
and drug administration about draft penalties. Instead of being for Disease Control and Prevention
revisions to strengthen China's food compensated for 10 times the price estimates that for every one case of
safety laws. Zhang Yong reportedly of any problematic food, under the Salmonella that is detected,
told lawmakers at the bimonthly new law, Chinese consumers would another 29 cases go undetected.
session of the Standing Committee be able to collect three times the Those estimates would suggest the
of the National People's Congress price of any loss they may suffer Foster Farms outbreak may have
that food safety is improving, but from food-related problems. affected more than 17,000 people.
FDA PROPOSAL TO PUT ADDED that recent problems show that “the Producer fines would go from 10 to
situation remains severe.” He said 30 times the value of any SUGARS IN NUTRITION FACTS
that the existing regulatory system substandard food products. PANEL: Last week, legal analysts
is not effective, penalties are Government regulators would also for OFW Law published a blog
comparatively light, and it does not face stiff punishment for violations arguing that “Added Sugars” should
deter offenders. Recent headlines under the more stringent law. Any not be included in the Food and
in China and around the world have official who fails to respond to a Drug Administration's revamp of the
revealed shoddy practices such as food safety emergency would be Nutrition Facts panel. “The White
injecting clenbuterol into pork, demoted or dismissed, and those House seems to be pushing FDA to
recycling cooking oil from leftovers caught abusing their power, require more, including the
in restaurant kitchens, and passing neglecting their duty for personal disclosure of 'Added Sugars,' which
rat and fox meat off as mutton and gain, or found responsible for food may not be necessary or even
beef. Reports that illegal additives safety cover-ups would face criminal beneficial,” wrote Richard L. Frank
have been used to grow bean penalties. and Bruce Silverglade. “The FDA
SALMONELLA OUTBREAK LINKED spouts have prompted officials to announcement on 'Added Sugars'
seize large amounts of the product, TO FOSTER FARMS CHICKEN TOPS labeling filled the national news for
and, in January, Walmart stores in 600 CASES : At least 27 additional days even though the agency had
China recalled donkey meat after it cases of Salmonella infection have not conducted its research project
was found to contain fox DNA. Due emerged in the ongoing Salmonella to determine if the disclosure would
to a widely publicized scandal outbreak linked to Foster Farms be helpful to consumers.” The post
involving infant formula chicken, bringing the total case includes quotes from FDA sources
contaminated with melamine, a count to 601. The new cases have who suggest there is a lack of
special provision was added to the been reported by the California evidence that added sugars directly
proposed bill. Producers would have Department of Public Health, which contribute to obesity and heart
to test every batch of infant formula has now seen 468 of the cases — disease and to weight gain more
they make, conduct regular internal by far the most of any state. The than any other calorie source. Jim
inspections, and submit reports to Salmonella outbreak linked to O'Hara, health promotion policy
regulators. The plan, Zhang Foster Farms chicken was first director with the Center for Science
indicated to lawmakers, is to amend reported in October 2013, with new in the Public Interest (CSPI),
FOOD INGREDIENTS ARTICLE
51THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l
responded to the post, stating that would be an improvement. “This comments. Because of the
these “caveats” in FDA's proposal unprecedented mandate by FDA potential for attorney-client privilege
are not determinative. “Agencies strays beyond the agency's and work-product exclusions,
regularly offer a review of evidence traditional legal authority and prosecutors have suggested that a
both supporting and opposing a subjects food companies to so-called “taint team” from the U.S.
proposed regulation,” he wrote. additional costs that are ultimately Department of Justice review
In Defense Of The Added passed on to consumers,” Frank documents from the former
Sugars Label, O'hara Cited The and Silverglade wrote. “The White corporate attorneys before any are
American Heart Association (aha) House should direct FDA to live up cleared and turned over to the
recommendation that women and to the Administration's purported government. Parnell's response
men consume no more than 25 commitment to evidence-based motion indicates that the defense
grams and 37.5 grams per day from science and regulatory policy, and attorneys want to conduct their own
added sugars, respectively. He also withdraw the proposed 'Added review after the taint team's work is
referenced World Health Sugars' labeling regulation.” Debate completed. “Nevertheless, what is
Organization guidelines that sugar on various aspects of the proposed clear at this stage is that a written
intake be limited to 10 percent of Nutrition Label changes is expected joint defense agreement is in place
total energy intake per day, and that to flare up later this week when FDA that governs and informs the
5 percent — including both added holds its public meeting on the parties, including PCA and its
and natural sugars — would have proposed rules on Thursday. former counsel, regarding what
DEFENSE ERECTS ROADBLOCKS an added health benefit. “And, in power individual members of the
fact, the U.S. 2010 Dietary agreement possess to waive any TO DOCUMENTS FROM FORMER
Guidelines estimate that 16 percent privileges,” Parnell's attorneys say. PCA ATTORNEYS : While other pre-
of the total calories in the average They want the court to prohibit the trial issues will be heard today by
American diet comes from added government from accessing the US District Court Judge W. Louis
sugars, which it notes 'often supply material because they say Sands in Albany, GA, Stewart
calories but few or no essential prosecutors have “manufactured a Parnell's attorneys won't agree to
nutrients and no dietary fiber,'” time constraint” so close to the the hearing on the “potentially
O'Hara wrote. Citing a lack of trial. The trial of Parnell, his brother privileged documents” which the
consumer research, Frank and Michael Parnell, and PCA's former government wants to collect from
Silverglade also wonder how the quality control manager, Mary former Peanut Corporation of
added sugars information would Wilkerson, stems from a February American attorneys before the start
impact consumers: “Will this be 2013 indictment charging them with of the scheduled July 14 jury trial.
another misguided attempt by the a total of 76 federal felony counts, For the first time, Parnell's
administration and only confuse including fraud and conspiracy, attorneys also disclosed the
consumers more? Will it provide any along with violations of federal food existence of a “joint defense
long-term benefits to Americans' laws. The charges followed from the agreement” that is “in place” and
health?” While the authors 2008-09 Salmonella outbreak “affects what may or may not be
acknowledge that not all calories traced back to PCA's peanut disclosed.” The joint defense
are the same, they suggest that processing plant in Blakely, GA. agreement binds the three
just disclosing them in a more That outbreak sickened 700 and defendants, all former PCA
conspicuous manner on labels killed nine.executives, to “a privilege review”of
FOOD INGREDIENTS ARTICLE
52 THE MAZADA PHARMA GUIDE 30 June - 6 July 2014l
Surya Fine Chem..................................50(+)-o-o'dibenzoyl-d-tartaric Acid 3-(4-amino Pheyl) 1,2-4-oxadiazol-
Jay Chemicals......................................49Dhruv Chem Industries.........................36 Jay Chemicals......................................49
3 Bromo Anisole1-butane 5-methylindole
Dhruv Chem Industries.........................36Molychem.............................................24 Jay Chemicals......................................49
K. Sevantilal & Co.................................Back Cover PelletsAmino Acid
Absorption Indicator Meso Carbon India Pvt. Ltd..................49K. P. Manish Global Ingredients P.........5
Molychem.............................................24 Activated Carbon / Charcool Molychem.............................................24Acarbose S. V. Enterprises...................................50 Powder Pack Chem..............................38International Drug & Chemical Co........44 Nova Chemie........................................25
AmisulprideAcebrophylline Adenosil Cobalamine Om Laboratories...................................16Luconic Chemicals...............................16 Padmavati Pharmachem......................Back Inside Aril Pharmaceuticals.............................10Aceclofenac Aerosil Global Pharma......................................6
Hrishabh Life Sciences.........................49 Western Pharma...................................46 AmitriptylineAjmera Pharmasure Pvt. Ltd................20 Bhawanishankar Company...................Gate Fold Luconic Chemicals...............................16Devson Impex Pvt. Ltd.........................14 Ravi Chem............................................39
Amitriptyline HclJ. B. Khokhani & Co.............................Front Cover Agar Agar Aril Pharmaceuticals.............................10Acesulfame K Titan Biotech Ltd...................................29 Aligns International...............................19Bhawanishankar Company...................Gate Fold Ajinomoto Amlodipine BesylateAcetazolamide Devson Impex Pvt. Ltd.........................14 Passim Medichem Agencies.................45D K Pharmchem Pvt. Ltd......................Front Inside Albendazole Aligns International...............................19Acetic Acid For Hplc Aril Pharmaceuticals.............................10Nova Chemie........................................25
Western Pharma...................................46Molychem.............................................24 Bhawanishankar Company...................Gate Fold
Global Pharma......................................6 Ammonium Bromide / ChlorideAcetly Bromide
Artesune Sterile Global Pharma......................................6Betamethasone Di PropionateGlobal Pharma......................................6 Beef ExtractGlobal Pharma......................................6
Bhawanishankar Company...................Gate FoldAzathioprine Bisoprolol FumarateGlobal Pharma......................................6Aril Pharmaceuticals.............................10 Panchsheel Organics Ltd.....................8Ravi Chem............................................39Global Pharma......................................6 Black / Brown LakeS. V. Enterprises...................................50Panchsheel Organics Ltd.....................8 Standardcon Pvt. Ltd............................40Benzyl Benzoate / BromideAzithromycin Black Current / RiseBliss Unlimited......................................27Cosmos International............................36 North India Pharma..............................23Dhruv Chem Industries.........................36Rumit International...............................28
Bleach ShellacGlobal Pharma......................................6Azithromycin Amine Western Pharma...................................46Ravi Chem............................................39Rumit International...............................28 Ravi Chem............................................39S. V. Enterprises...................................50B.h.a / B.h.t Blended Lakes : Apple / Pea GreenBenzylhydrazine Di-hydrochlorideSiddhivinayak Pharma..........................40 Standardcon Pvt. Ltd............................40Jay Chemicals......................................49Baclofen Boiler ChemicalBest For All Heat Sensitive ProductsLuconic Chemicals...............................16 Surya Fine Chem..................................50Microfine Pharma (p) Ltd......................49Global Pharma......................................6
BonisteinBeta Carotene / CyclodextrineBeclomethasone Dipropionate K. Sevantilal & Co.................................Back Cover
PRODUCT INDEX
55THE MAZADA PHARMA GUIDE 30 June - 6 July 2014?
Borage Oil Caffiene Capsicum Oleoresin 8% Liquid
K. Sevantilal & Co.................................Back Cover Bhawanishankar Company...................Gate Fold North India Pharma..............................23
Boricin Pharma Calcidol Carbocisteine
Ravi Chem............................................39 Siddhivinayak Pharma..........................40 Panchsheel Organics Ltd.....................8
North India Pharma..............................23Bortezomib Ihs 980, 981
CalciumKhandelwal Laboratories Pvt Ltd..........26 Ravi Chem............................................39
Ekta Export...........................................16Bovine Colostrum Powder Carbonyl Iron
Calcium Aspartate / BromideNorth India Pharma..............................23 Aril Pharmaceuticals.............................10
North India Pharma..............................23 Bhawanishankar Company...................Gate FoldBrilliant Blue Fcf LakeDhruv Chem Industries.........................36 North India Pharma..............................23Standardcon Pvt. Ltd............................40Calcium Carbonanate Natural / Calcite CarboplatinBromelainGangotri Inorganic (p) Ltd.....................13 Khandelwal Laboratories Pvt Ltd..........26International Drug & Chemical Co........44Calcium Carbonate / Chloride Carboplatin/cisplatinNorth India Pharma..............................23
Panchsheel Organics Ltd.....................8 Ravi Chem............................................39Camylofine Dihcl Global Merchants.................................49BusalphanKhandelwal Laboratories Pvt Ltd..........26 Global Pharma......................................6Chemipack Corporation........................22Canthaxanthin Ceramide IiButyl ParabenNorth India Pharma..............................23 K. Sevantilal & Co.................................Back CoverLaxachem Organics Pvt. Ltd................44Capacity Of More Than 500 Mt Per Ceric Ammonium NitrateButylated Hydroxy Toluene / AnisoleYear Molychem.............................................24S. V. Enterprises...................................50Microfine Pharma (p) Ltd......................49 Ceric Ammonium SulphateSna Healthcare Pvt. Ltd........................45
Capecitabine Molychem.............................................24C. A. P. B / C. M. 100 / C. P. M / C.a.pKhandelwal Laboratories Pvt Ltd..........26 Ceto Steryl AlcoholBhawanishankar Company...................Gate FoldChemipack Corporation........................22Niram Chemicals..................................45 Ravi Chem............................................39Panchsheel Organics Ltd.....................8Passim Medichem Agencies.................45 Cetodet 500
Cetrimide Agar Aril Pharmaceuticals.............................10Chromium PicolinateTitan Biotech Ltd...................................29 Clopidogrel BisulphateAligns International...............................19
Cetrimide Powder Aligns International...............................19CilnidipineGlobal Pharma......................................6 ClosantalInternational Drug & Chemical Co........44
Cetrizine Hcl Global Pharma......................................6Cinnamon ExtractBhawanishankar Company...................Gate Fold Closantel Sodium.Aligns International...............................19
Khandelwal Laboratories Pvt Ltd..........26Ravi Chem............................................39 CoenzymeBhawanishankar Company...................Gate Fold Citalopram North India Pharma..............................23Chlordiazepoxide Aril Pharmaceuticals.............................10 Coleus Forskohli
Global Pharma......................................6Panchsheel Organics Ltd.....................8 Aligns International...............................19Hrishabh Life Sciences.........................49Aril Pharmaceuticals.............................10
Colistine SulphateCitramideChlorella Powder Padmavati Pharmachem......................Back InsideWestern Pharma...................................46North India Pharma..............................23
Collagen PeptideCitric AcidChlorhexidine Gluconate North India Pharma..............................23Siddhivinayak Pharma..........................40Western Pharma...................................46
Aril Pharmaceuticals.............................10 Global Pharma......................................6Chlorzoxazone International Drug & Chemical Co........44Clobetamethasone PropionateBhawanishankar Company...................Gate Fold Siddhivinayak Pharma..........................40Global Pharma......................................6J. B. Khokhani & Co.............................Front Cover
Aligns International...............................19 North India Pharma..............................23 Nova Chemie........................................25
D-alpha-tocopheryl Acetate Di Calcium Phosphate Di Basic Dithizone
K. Sevantilal & Co.................................Back Cover Ravi Chem............................................39 Molychem.............................................24
Dapoxetin Diethylamine Divalporate Sodium
Chemipack Corporation........................22 R R Innovative Pvt Ltd..........................17 Mirambika Pigment...............................38
Luconic Chemicals...............................16 Di Sodium Hydrogen Citrate Divalporax
Dapoxetine Hcl Ravi Chem............................................39 Global Pharma......................................6
North India Pharma..............................23 Luconic Chemicals...............................16DoethiprinChandra Biotech...................................14Dye & StainsChemipack Corporation........................22
EthanolPowder Pack Chem..............................38DomperidoneNova Chemie........................................25Dyes And IndicatorsTamarind Drugs & Cosmetics...............12
Ether 40-60 & 60-80Molychem.............................................24DomperidoneMolychem.............................................24E. T. P. ChemicalsSri Pharmacare.....................................46
Ethidium BromideSurya Fine Chem..................................50Dothiepine HclMolychem.............................................24Edta SaltAril Pharmaceuticals.............................10
Dried Ferrous SulphateErythromycin Estolate / Thiocyanate / EtoricoxibSushant Industries................................39Stearate Aril Pharmaceuticals.............................10Ajmera Pharmasure Pvt. Ltd................20Global Pharma......................................6 EzetimibePravina Pharma Chem Products..........46Rumit International...............................28S. V. Enterprises...................................50 Aligns International...............................19Erythrosine LakeDrotavarine FamotidineStandardcon Pvt. Ltd............................40Aril Pharmaceuticals.............................10 Luconic Chemicals...............................16EscitalopramLuconic Chemicals...............................16 Fast Green Fcf LakeGlobal Pharma......................................6Dry Vitamin A Acetate Standardcon Pvt. Ltd............................40Hrishabh Life Sciences.........................49K. Sevantilal & Co.................................Back Cover Fast Red E LakeEscitalopram OxalateDry Vitamin D3 Standardcon Pvt. Ltd............................40Chemipack Corporation........................22K. Sevantilal & Co.................................Back Cover FenbendazoleAril Pharmaceuticals.............................10
Dry Vitamin E Global Pharma......................................6Bhawanishankar Company...................Gate Fold
K. Sevantilal & Co.................................Back Cover FenofibrateGlobal Pharma......................................6Dry Vitamin K D K Pharmchem Pvt. Ltd......................Front Inside
Esomeprazole Pellets 8.5%,22.5%K. Sevantilal & Co.................................Back Cover Fenofibric AcidAril Pharmaceuticals.............................10Duloxetine D K Pharmchem Pvt. Ltd......................Front Inside
North India Pharma..............................23 Devson Impex Pvt. Ltd.........................14 Aril Pharmaceuticals.............................10
Tamarind Drugs & Cosmetics...............12Fungal Alpha AmylaseFerrous Gluconate / Sulphate Aligns International...............................19International Drug & Chemical Co........44Bhawanishankar Company...................Gate Fold Aril Pharmaceuticals.............................10
Fungal DiastateSushant Industries................................39 Global Pharma......................................6Passim Medichem Agencies.................45
Ferrous Sulphate Heptahydrate International Drug & Chemical Co........44FurazolidonePravina Pharma Chem Products..........46 GlipizideCosmos International............................36
Aril Pharmaceuticals.............................10 Global Pharma......................................6Nova Chemie........................................25
Tamarind Drugs & Cosmetics...............12FinastrideFurosemide International Drug & Chemical Co........44Chemipack Corporation........................22D K Pharmchem Pvt. Ltd......................Front Inside
IsonalineIndole-3-butyric AcidHydrochloric K. Sevantilal & Co.................................Back CoverMolychem.............................................24Surya Fine Chem..................................50
Itopride HclIndomethacinHydrochloride Acetate D K Pharmchem Pvt. Ltd......................Front InsidePanchsheel Organics Ltd.....................8Rumit International...............................28
IvermactinInsitolHydrocortisone Base Global Pharma......................................6K. Sevantilal & Co.................................Back CoverAjmera Pharmasure Pvt. Ltd................20 Om Laboratories...................................16IodineHydroquinone Jojoba Beads / OilG. Amphray Pharmaceuticals Pvt. Ltd..11Padmavati Pharmachem......................Back Inside Global Merchants.................................49Iodine PrillsHydroxy Progesterone Acetate K. Sevantilal & Co.................................Back CoverIndenta Chemicals (india) Pvt. Ltd........37Ajmera Pharmasure Pvt. Ltd................20 KaolinIon Exchange ResinsHydroxy Propyl Betacyclodextrine Ravi Chem............................................39Molychem.............................................24Padmavati Pharmachem......................Back Inside Kaolin PowderIrinotecanHydroxyprogesterone Caproate Sushant Industries................................39Aligns International...............................19Panchsheel Organics Ltd.....................8 Keterolac Hcl / TromethamineIrinotecan HclHydroxytyrosol Chemipack Corporation........................22Khandelwal Laboratories Pvt Ltd..........26 Aril Pharmaceuticals.............................10Aligns International...............................19Iron (iii) Hydroxy Poly. Complex Global Pharma......................................6HydroxyureaPanchsheel Organics Ltd.....................8 Ketotifen FumarateKhandelwal Laboratories Pvt Ltd..........26Iron Dextran Panchsheel Organics Ltd.....................8Hydroxyzine HclChemipack Corporation........................22 Kojic Acid & Kojic Acid DipalmitatePanchsheel Organics Ltd.....................8Iron Iii Polymaltos North India Pharma..............................23Hyoscine Base & Its SaltAril Pharmaceuticals.............................10 Kozic AcidBhawanishankar Company...................Gate FoldLuconic Chemicals...............................16 Global Pharma......................................6I. P. A / I.p.mIron Pairing Reagents L - ArginineWestern Pharma...................................46Powder Pack Chem..............................38 Devson Impex Pvt. Ltd.........................14Molychem.............................................24Iron Pellets K. P. Manish Global Ingredients P.........5Ravi Chem............................................39
Devson Impex Pvt. Ltd.........................14 Om Laboratories...................................16L - Arginine Hcl UspK. P. Manish Global Ingredients P.........5 Light Creosote OilK. P. Manish Global Ingredients P.........5
L - Valine Global Merchants.................................49L - Aspartic AcidDevson Impex Pvt. Ltd.........................14 Light Liquid ParaffinDevson Impex Pvt. Ltd.........................14K. P. Manish Global Ingredients P.........5 Bhawanishankar Company...................Gate FoldL - Carnitine BaseL. I. Q. Ammonia Light Liquid ParaffinAligns International...............................19Sima Chemicals....................................50 Ravi Chem............................................39L - Cysteine UspLabetalol Hcl LignocaineK. P. Manish Global Ingredients P.........5Aril Pharmaceuticals.............................10 Global Pharma......................................6L - Glutamic AcidLactalbumin Hydrolysate LinaloolRavi Chem............................................39Titan Biotech Ltd...................................29Devson Impex Pvt. Ltd.........................14 K. Sevantilal & Co.................................Back CoverLactic AcidK. P. Manish Global Ingredients P.........5 Linalyl AcetateSiddhivinayak Pharma..........................40L - Glutamine K. Sevantilal & Co.................................Back CoverLactoseDevson Impex Pvt. Ltd.........................14 Linseed OilWestern Pharma...................................46L - Glutathione Reduced Siddhivinayak Pharma..........................40Bhawanishankar Company...................Gate FoldNorth India Pharma..............................23 Liquid Bromine / Glucose / ParaffinDevson Impex Pvt. Ltd.........................14
L - Histidine Ad Pharmachem (p) Ltd.......................46Lactulose ConcentrateDevson Impex Pvt. Ltd.........................14 Bhawanishankar Company...................Gate FoldBhawanishankar Company...................Gate Fold Niram Chemicals..................................45L - IsoleuicineLactulose Ravi Chem............................................39K. P. Manish Global Ingredients P.........5International Drug & Chemical Co........44 Siddhivinayak Pharma..........................40Devson Impex Pvt. Ltd.........................14
Powder Ad Pharmachem (p) Ltd.......................46 Global Pharma......................................6Ravi Chem............................................39
Mercuric Chloride / Nitrate / Sulphate K. Sevantilal & Co.................................Back CoverMagnesium Metal Turnnings / Powder Molychem.............................................24 Ravi Chem............................................39Euro Fine Chemicals............................49 Panchsheel Organics Ltd.....................8MesalamineMagnesium Oxide Light Methylene ChlorideD K Pharmchem Pvt. Ltd......................Front InsideBhawanishankar Company...................Gate Fold Bhawanishankar Company...................Gate FoldMeta NitrobenzaldehydeMagnesium Stearate MetochlopramideRumit International...............................28Siddhivinayak Pharma..........................40 Global Pharma......................................6Meta Nitrobenzoic AcidMagnesium Stearate / Trisilicate Metoprolol Succinate / TartarateRumit International...............................28Bhawanishankar Company...................Gate Fold International Drug & Chemical Co........44Meta Nitrobenzyl AlcoholRavi Chem............................................39
Mirtazapine N - Hexane Panchsheel Organics Ltd.....................8
Chemipack Corporation........................22 Molychem.............................................24 Non IonAril Pharmaceuticals.............................10 N - Hexyl Bromide Ravi Chem............................................39
Misoprostol Dhruv Chem Industries.........................36 Norethisterone Acetate / BaseInternational Drug & Chemical Co........44 N - Methyl Piperazine Ajmera Pharmasure Pvt. Ltd................20
Mixed Carotenoids Rumit International...............................28 NorfloxacinNorth India Pharma..............................23 N - Octyl Bromide Ajmera Pharmasure Pvt. Ltd................20
Para Nitrobenzaldehyde Phenylephriene HydrochlorideOrtho Nitrobenzaldehyde Rumit International...............................28 Sna Healthcare Pvt. Ltd........................45Rumit International...............................28 Hrishabh Life Sciences.........................49Para Nitrobenzyl AlcoholOrtho Nitrobenzyl Alcohol Phenytoin SodiumRumit International...............................28Rumit International...............................28 Luconic Chemicals...............................16Paraben Salts Plain / SodiumOtilonium Bromide Phosphrous Tri BromideRavi Chem............................................39Khandelwal Laboratories Pvt Ltd..........26 Dhruv Chem Industries.........................36ParacetamolOxalaplatin PhtyalylsulfathiazoleBhawanishankar Company...................Gate FoldKhandelwal Laboratories Pvt Ltd..........26 K. Sevantilal & Co.................................Back Cover G. Amphray Pharmaceuticals Pvt. Ltd..11
Oxaliplatin Sri Pharmacare.....................................46 PhytantriolChemipack Corporation........................22 Paraffin Liquid Light / Heavy K. Sevantilal & Co.................................Back Cover
Bhawanishankar Company...................Gate Fold Bhawanishankar Company...................Gate FoldP. E. G / P. V. P. K / P.g. / P.c.m.cInternational Drug & Chemical Co........44 PiroxicamBhawanishankar Company...................Gate FoldPassim Medichem Agencies.................45 Luconic Chemicals...............................16Niram Chemicals..................................45PeptonePadmavati Pharmachem......................Back Inside Plant Growth RegulatorsMolychem.............................................24Ravi Chem............................................39 Molychem.............................................24
Ravi Chem............................................39 Permethrin Liq. Poly DextroseSiddhivinayak Pharma..........................40 Aril Pharmaceuticals.............................10 Devson Impex Pvt. Ltd.........................14Paclitaxel North India Pharma..............................23
Mirambika Pigment...............................38Surya Fine Chem..................................50 Sri Pharmacare.....................................46Aril Pharmaceuticals.............................10
Bhawanishankar Company...................Gate FoldRuthenium Red / Trichloride NitrateNiram Chemicals..................................45Molychem.............................................24 Siddhivinayak Pharma..........................40Ravi Chem............................................39 Global Merchants.................................49RutinSiddhivinayak Pharma..........................40 Neha Enterprises..................................50Panchsheel Organics Ltd.....................8Simvastatin Sodium Potassium TartrateInternational Drug & Chemical Co........44Tamarind Drugs & Cosmetics...............12 Indenta Chemicals (india) Pvt. Ltd........37Rutoside TrihydratePanchsheel Organics Ltd.....................8
Sodium Propyl ParabenNorth India Pharma..............................23Six Independent Stream Laxachem Organics Pvt. Ltd................44S. L. E. S / S. L. S / S. S. G / S. T. P. PMicrofine Pharma (p) Ltd......................49
Sodium Saccharin / SaltBhawanishankar Company...................Gate FoldSmecGlobal Merchants.................................49 Cosmos International............................36K. Sevantilal & Co.................................Back CoverNiram Chemicals..................................45 Bhawanishankar Company...................Gate FoldSodiumSiddhivinayak Pharma..........................40 International Drug & Chemical Co........44
SorafenibAril Pharmaceuticals.............................10Serratiopeptidase Plain / Granules North India Pharma..............................23 Khandelwal Laboratories Pvt Ltd..........26International Drug & Chemical Co........44 Rumit International...............................28 SorbitolChemipack Corporation........................22
Bhawanishankar Company...................Gate Fold Ravi Chem............................................39Sodium Hydrogen SulphideSiddhivinayak Pharma..........................40Shampoo Base Euro Fine Chemicals............................49
Global Merchants.................................49Chemipack Corporation........................22 Global Pharma......................................6
J. B. Khokhani & Co.............................Front Cover Laxachem Organics Pvt. Ltd................44Trioxsalen
K. Sevantilal & Co.................................Back Cover YogurteneLuconic Chemicals...............................16Nova Chemie........................................25 K. Sevantilal & Co.................................Back CoverChandra Biotech...................................14Padmavati Pharmachem......................Back Inside
Z. P. T. OTriprolidine HclPanchsheel Organics Ltd.....................8
Global Pharma......................................6Panchsheel Organics Ltd.....................8 Ravi Chem............................................39K. Sevantilal & Co.................................Back CoverD K Pharmchem Pvt. Ltd......................Front Inside Siddhivinayak Pharma..........................40Siddhivinayak Pharma..........................40
Troxerutin Vitamin K1 / K2 / K3 / K7ZeaxanthinNorth India Pharma..............................23 K. Sevantilal & Co.................................Back CoverK. Sevantilal & Co.................................Back Cover
Trypsin Aligns International...............................19Zeaxanthin PowderInternational Drug & Chemical Co........44Passim Medichem Agencies.................45North India Pharma..............................23North India Pharma..............................23Trypsin ChymotrypsinZidovudineNova Chemie........................................25International Drug & Chemical Co........44Aligns International...............................19Panchsheel Organics Ltd.....................8Passim Medichem Agencies.................45
Panchsheel Organics Ltd.....................8Padmavati Pharmachem......................Back Inside White Petroleum Jelly
PRODUCT INDEX
69THE MAZADA PHARMA GUIDE 30 June - 6 July 2014?
Aarambh Life Science.............................................Ear Panel.......Mumbai Meso Carbon India Pvt. Ltd. ..................................49...................Mumbai
Ad Pharmachem (p) Ltd..........................................46...................Aurangabad Microfine Pharma (p) Ltd........................................49...................Mumbai
Aril Pharmaceuticals...............................................10...................Mumbai North India Pharma.................................................23...................Delhi
Bhawanishankar Company.....................................Gate Fold.......Mumbai Nova Chemie..........................................................25...................Mumbai
Bliss Unlimited .......................................................27...................Mumbai Om Laboratories.....................................................16...................Ahmedabad
D K Pharmchem Pvt. Ltd........................................Front Inside....Mumbai Panchsheel Organics Ltd........................................8.....................Mumbai
Euro Fine Chemicals..............................................49...................Mumbai Prudence Pharmachem .........................................Ear Panel.......Ankleshwar
G. Amphray Pharmaceuticals Pvt. Ltd....................11...................Mumbai R R Innovative Pvt Ltd............................................17...................Mumbai
Gangotri Inorganic (p) Ltd. .....................................13...................Gujarat Ravi Chem .............................................................39...................Mumbai
Global Merchants....................................................49...................Mumbai Rumit International .................................................28...................Mumbai
Global Pharma........................................................6.....................Mumbai S. V. Enterprises.....................................................50...................Mumbai
Hrishabh Life Sciences...........................................49...................Mumbai Siddhivinayak Pharma............................................40...................Mumbai
International Drug & Chemical Co..........................44...................Mumbai Sna Healthcare Pvt. Ltd..........................................45...................Mumbai
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Jay Chem Marketing...............................................44...................Mumbai Standardcon Pvt. Ltd..............................................40...................Mumbai
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K. P. Manish Global Ingredients P. .........................5.....................Mumbai Sushant Industries..................................................39...................Mumbai
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