The histaminergic neurotransmitter system – its development and role in neuronal plasticity in zebrafish, Danio rerio Jenny Maria Sundvik Neuroscience Center and Institute of Biomedicine, Anatomy Faculty of Medicine University of Helsinki Finland and Helsinki Biomedical Graduate Program ACADEMIC DISSERTATION To be publicly discussed with the permission of the Faculty of Medicine, University of Helsinki, in Lecture Hall 2, Haartman Institute, Haartmaninkatu 3, on August 24 th 2012, at 12 noon. Helsinki 2012
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The histaminergic neurotransmitter system
– its development and role in neuronal plasticity in
zebrafish, Danio rerio
Jenny Maria Sundvik
Neuroscience Center and
Institute of Biomedicine, Anatomy
Faculty of Medicine
University of Helsinki
Finland
and
Helsinki Biomedical Graduate Program
ACADEMIC DISSERTATION
To be publicly discussed with the permission of the Faculty of Medicine, University
of Helsinki, in Lecture Hall 2, Haartman Institute, Haartmaninkatu 3,
on August 24th
2012, at 12 noon.
Helsinki 2012
Supervised by
Professor Pertti Panula
Neuroscience Center and Institute of Biomedicine, Anatomy
that I had the pleasure to interact with, for introducing me to the wonderful world
of neuroscience. Thank you for the time spent inside and outside the lab. I really
enjoyed working with and getting to know all of you! I would especially like to
mention Dr. Saara Nuutinen and Dr. Jari Rossi who kindly commented on the first
versions of my thesis. Mikko Liljeström and Dr. Mika Hukkanen at the Biomedicum
Imaging Unit are thanked for their never ending patience regarding questions
about confocal microscopes and image processing. I furthermore would like to
thank all the scientists who visited the pp-group in Helsinki, especially Dr. Mario de
Bono, Dr. Harry Burgess, Professor Robert Cornell, Professor Helmut Haas, Dr.
Marnie Halpern, Dr. Petronella Kettunen, Dr. Donald O’Malley, Professor Hiroshi
Ohtsu, Professor Michalis Pavlidis, Dr. Gonzalo de Polavieja, Professor Manuel
Portavella, and Dr. Maximiliano Suster for the discussions we had regarding
science and zebrafish. Friends in and outside science – you all contributed to this
thesis. I am very grateful for all the fun together, and for having you in my life!
My deepest gratitude goes to my loved ones, to my family including all possible
extensions. Your joyousness, and endless support and faith in me keep on amazing
me. You will always be in my heart.
Maria Sundvik
Helsingfors, 2012
72
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