Rough Endoplasmic Rough Endoplasmic Reticulum (RER) Reticulum (RER) • The RER is dotted with The RER is dotted with ribosomes. (Which is why it ribosomes. (Which is why it is called “rough.”) is called “rough.”) • The RER is involved with The RER is involved with protein production, protein protein production, protein folding, quality control folding, quality control and dispatch. and dispatch. • The RER is involved with The RER is involved with the synthesis of proteins. the synthesis of proteins. They produce and process They produce and process specific proteins at specific proteins at ribosomal sites. ribosomal sites. • Consists of network-like Consists of network-like tunnels with tubules, tunnels with tubules, vesicles and cisternae vesicles and cisternae which is held together by which is held together by the cytoskeleton of the the cytoskeleton of the cell. cell.