The balance between apoB and apoA-I, i.e. the apoB/apoA-I ratio, indicates cardiovascular risk; the higher the ratio, the higher is the risk G. Walldius.

The balance between apoB and apoA-I, i.e. the apoB/apoA-I ratio, indicates cardiovascular risk; the

higher the ratio, the higher is the risk

G. Walldius and I . Jungner J. Internal Medicine 2006; 259: 493–519

AMORIS: Fatal MIMen, n=1267: adjusted for age, TC, and TG


Odds ratio for fatal myocardial infarction in men (hatched line) and women (solid line) in relation to the apolipoprotein B (apoB)/apoA-I

ratio expressed in deciles (log-plot)


Odds ratio for fatal myocardial infarction in men and women pooled together in

relation to the apolipoprotein B (apoB)/apoA-I ratio expressed in deciles (log-plot)


The AMORIS study: values for low-density lipoprotein cholesterol (LDL C;

x-axis) versus apolipoprotein B (apoB; y-axis) in 50–70-year-old men


Different values for LDL C correspond to values for the

apoB/apoA-I ratio according to the regression line between LDL C (x-axis) versus the apoB/apoA-I

ratio (y-axis) for men and women


The AMORIS study: glucose and the apoB)/apoA-I ratio versus relative risk

of fatal myocardial infarction (y-axis) in men with elevated glucose values


Relative risk of fatal myocardial infarction as a function of increasing glucose values and increasing values of the

apoB/apoA-I ratio in men and women


The AMORIS study: odds ratio for fatal stroke (all subtypes included)

in men and women pooled together in relation to the apoB/apoA-I ratio expressed in deciles (log-plot)


The AMORIS study: odds ratio for all events related to atherosclerosis (and ischaemia) in men and women

pooled together in relation to the apoB/apoA-I ratio expressed in deciles (log-plot)


The INTERHEART study: odds ratio for acute myocardial infarction in men and women pooled together in relation

to the apoB/apoA-I ratio expressed in deciles (log-plot)


The INTERHEART study: PAR values for the nine risk variables measured in the trial


Clinical events and manifestations of atherosclerosis associated

with high values of the apoB/apoA-I ratio independent of

LDL C values and/or other conventional risk factors


Risk of myocardial infarction in relation to increasing values of the apoB/apoA-I ratio


The balance between apoB and apoA-I, i.e. the apoB/apoA-I ratio, indicates cardiovascular risk; the higher the ratio, the higher is the risk G. Walldius.

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