Page 1
Supplemental Table and Figure Legends
Table S1. Clinical characteristics and hepatic enzyme activities of human participants.
(-) NAFLD (N=9) (+) NAFLD (N=12)
MALE (N=7)
FEMALE
(N=2)
MALE
(N=5)
FEMALE
(N=7)
Age (years) 62±7.4 44±0 67±8.6 62±9.3
BMI (kg/m2) 22.2±1.8 22.0±2.1 26.7±5.5
* 24.7±1.4
##
Comorbidities
Hypertension (%) 42.9 50 60 42.9
Diabetes mellitus (%) 14.3 0 0 28.6
Dyslipidemia (%) 0 0 40 71.4
Liver biochemistries
ALT(U/L) 17.7±8.1 9±0 18.6±13.3 18.7±10.1
AST(U/L) 20.3±8.2 11±2.8 22.2±6.8 18.3±3.8
Values expressed are mean ±SD.
BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase.
*P<0.01, ##
P<0.005 vs. controls
Table S2. Identification of proteins associated with LDs of human liver sample 1.
Reference MW Accession
Scan(s) Sp RSp
1 clathrin heavy chain 1 191612.6 4758012
2 alcohol dehydrogenase 4 40221.5 71565152
3 long-chain-fatty-acid--CoA ligase 1 77942.9 40807491
4 ras GTPase-activating-like protein IQGAP2 180577.0 116089337
5 spectrin alpha chain, brain isoform 1 285091.3 194595509
6 dimethylaniline monooxygenase [N-oxide-forming] 3 60033.2 50541961
7 myosin-9 226529.8 12667788
8 tubulin beta-2A chain 49906.7 4507729
9 epoxide hydrolase 1 precursor 52948.5 209862837
10 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase
(cyclizing) 58946.8 20149621
11 17-beta-hydroxysteroid dehydrogenase 13 isoform B 29604.7 210032112
12 spectrin beta chain, brain 1 isoform 1 274606.5 112382250
13 peroxisomal multifunctional enzyme type 2 isoform 1 83024.9 313482810
14 alpha-actinin-4 104853.3 12025678
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15 plectin isoform 1e 513705.9 41322908
16 methyltransferase-like protein 7A precursor 28318.9 89145417
17 UTP--glucose-1-phosphate uridylyltransferase isoform a 56939.9 48255966
18 apolipoprotein B-100 precursor 515528.6 105990532
19 fatty acid synthase 273423.2 41872631
20 ATP synthase subunit beta, mitochondrial precursor 56559.5 32189394
21 perilipin-2 48075.1 34577059
22 peroxisomal bifunctional enzyme isoform 2 69153.5 261878539
23 calcium-binding mitochondrial carrier protein Aralar2 isoform 2 74175.1 7657581
24 probable saccharopine dehydrogenase 47151.1 55770836
25 long-chain-fatty-acid--CoA ligase 5 isoform a 82262.5 42794756
26 estradiol 17-beta-dehydrogenase 11 32935.6 142976729
27 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform c 116037.4 170295797
28 annexin A6 isoform 1 75872.8 71773329
29 tubulin alpha-1A chain 50135.3 17986283
30 trifunctional enzyme subunit alpha, mitochondrial precursor 82999.1 20127408
31 programmed cell death 6-interacting protein isoform 1 96022.6 22027538
32 17-beta-hydroxysteroid dehydrogenase type 6 35965.5 19743808
33 ATP synthase subunit alpha, mitochondrial precursor 59750.3 4757810
34 bile acyl-CoA synthetase precursor 75384.7 13325057
35 cytochrome P450 2E1 precursor 56848.6 10834998
36 formimidoyltransferase-cyclodeaminase 58926.2 11140815
37 NADH-cytochrome b5 reductase 3 isoform 2 31628.5 193794826
38 very long-chain acyl-CoA synthetase isoform 1 70311.8 227499619
39 D-3-phosphoglycerate dehydrogenase 56650.2 23308577
40 microsomal glutathione S-transferase 1 17598.6 9945306
41 prelamin-A/C isoform 1 precursor 74139.0 27436946
42 glutamate dehydrogenase 2, mitochondrial precursor 61433.6 31377775
43 acetyl-CoA carboxylase 2 precursor 276537.6 134142062
44 UDP-glucuronosyltransferase 2B4 precursor 60512.1 149944509
45 dehydrogenase/reductase SDR family member 1 33908.8 209862901
46 D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 38156.9 44680133
47 UDP-glucuronosyltransferase 2B7 precursor 60720.3 190194389
48 villin-1 92694.4 194394237
49 17-beta-hydroxysteroid dehydrogenase 13 isoform A 33655.2 210032110
50 non-specific lipid-transfer protein isoform 1 proprotein 58993.3 19923233
51 cytochrome P450 2C9 precursor 55627.6 13699818
52 eukaryotic initiation factor 4A-II 46402.0 83700235
53 cytochrome P450 2C19 precursor 55944.8 4503219
54 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
precursor 68569.0 4506675
55 protein transport protein Sec23A 86160.3 38202214
56 perilipin-3 isoform 1 47074.7 255958282
57 perilipin-1 55990.0 223718203
58 aldehyde dehydrogenase family 8 member A1 isoform 3 48035.6 301500698
59 liver carboxylesterase 1 isoform c precursor 62392.5 68508957
60 succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 72691.1 156416003
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61 tubulin beta chain 49670.5 29788785
62 elongation factor 2 95337.6 4503483
63 talin-1 269764.4 223029410
64 78 kDa glucose-regulated protein precursor 72332.5 16507237
65 serum paraoxonase/lactonase 3 39607.2 29788996
66 cytochrome P450 2D6 isoform 1 55730.1 40805836
67 amine oxidase [flavin-containing] B 58762.6 38202207
68 calnexin precursor 67567.8 10716563
69 vimentin 53651.3 62414289
70 corticosteroid 11-beta-dehydrogenase isozyme 1 32400.8 5031765
71 SEC14-like protein 2 isoform 1 46145.0 7110715
72 histone H4 11367.3 4504301
73 NADPH--cytochrome P450 reductase 77047.7 127139033
74 synaptic vesicle membrane protein VAT-1 homolog 41920.0 18379349
75 coatomer subunit alpha isoform 2 138344.7 148536853
76 lanosterol synthase isoform 2 82198.1 224177556
77 ADP/ATP translocase 2 32852.0 156071459
78 cullin-associated NEDD8-dissociated protein 1 136374.7 21361794
79 cytochrome P450 3A5 isoform 1 57108.3 4503231
80 actin, gamma-enteric smooth muscle isoform 1 precursor 41876.7 4501889
81 ras-related protein Rab-7a 23489.6 34147513
82 voltage-dependent anion-selective channel protein 3 isoform 2 30789.6 208879465
83 perilipin-4 134430.4 122937195
84 endoplasmin precursor 92468.2 4507677
85 alcohol dehydrogenase 1B 39835.3 34577061
86 protein ERGIC-53 precursor 57548.6 5031873
87 actin, cytoplasmic 1 41736.5 4501885
88 bile salt sulfotransferase 33779.6 29540545
89 sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 41900.0 8393516
90 myosin-Ib isoform 2 124949.7 44889481
91 aldehyde dehydrogenase, mitochondrial isoform 1 precursor 56380.9 25777732
92 membrane-associated progesterone receptor component 1 21671.0 5729875
93 AP-2 complex subunit alpha-1 isoform 2 105360.8 19913416
94 C-1-tetrahydrofolate synthase, cytoplasmic 101530.5 222136639
95 cathepsin D preproprotein 44552.0 4503143
96 hemoglobin subunit beta 15998.3 4504349
97 myosin-10 228996.6 41406064
98 AP-2 complex subunit beta isoform b 104551.9 4557469
99 desmoplakin isoform I 331771.4 58530840
100 hemoglobin subunit delta 16055.4 4504351
101 cytochrome b5 isoform 1 15330.0 41281768
102 ras-related protein Rab-14 23896.8 19923483
103 60S ribosomal protein L4 47697.0 16579885
104 hemoglobin subunit alpha 15257.4 4504345
105 serum paraoxonase/arylesterase 1 precursor 39731.0 19923106
106 fatty aldehyde dehydrogenase isoform 1 57669.1 73466520
107 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase 58068.1 166362724
108 cytochrome P450 3A7 57525.2 262290932
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109 trifunctional enzyme subunit beta, mitochondrial precursor 51294.1 4504327
110 apoptosis-inducing factor 1, mitochondrial isoform 2 precursor 66294.3 22202629
111 delta(24)-sterol reductase precursor 60100.9 13375618
112 annexin A4 36084.8 4502105
113 coatomer subunit beta 107141.5 7705369
114 cytochrome P450 2C18 isoform 1 precursor 55710.4 13699816
115 tricarboxylate transport protein, mitochondrial precursor 34012.4 21389315
116 histone H2B type 1-C/E/F/G/I 13906.0 4504271
117 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform 3 67523.9 316983158
118 protein diaphanous homolog 1 isoform 1 141346.4 119395758
119 protein transport protein Sec24A isoform 1 119748.6 116174780
120 cytochrome P450 4F11 precursor 60145.5 193083178
121 coatomer subunit gamma 97717.7 11559929
122 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform a precursor 165648.8 169790915
123 very long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2
precursor 68058.1 76496475
124 calcium-binding mitochondrial carrier protein Aralar1 74761.4 21361103
125 amine oxidase [flavin-containing] A 59681.3 4557735
126 peroxisomal multifunctional enzyme type 2 isoform 2 79685.9 4504505
127 fructose-bisphosphate aldolase B 39472.8 40354205
128 protein disulfide-isomerase precursor 57115.9 20070125
129 dimethylaniline monooxygenase [N-oxide-forming] 5 isoform 1 60220.2 221316672
130 estradiol 17-beta-dehydrogenase 2 42784.9 4504503
131 nicotinamide N-methyltransferase 29573.8 5453790
132 UDP-glucuronosyltransferase 1-7 precursor 59818.5 41282213
133 mitochondrial carrier homolog 2 33330.7 7657347
134 surfeit locus protein 4 30393.8 19557691
135 epoxide hydrolase 2 62615.4 27597073
136 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
isoform 1 precursor 69283.5 35493916
137 heat shock protein HSP 90-alpha isoform 1 98160.4 153792590
138 heat shock protein HSP 90-beta 83263.6 20149594
139 glutamate dehydrogenase 1, mitochondrial precursor 61397.5 4885281
140 retinol dehydrogenase 10 38087.3 25282469
141 prohibitin-2 isoform 1 33296.1 221307584
142 NAD(P) transhydrogenase, mitochondrial precursor 113894.8 122939155
143 oxysterol-binding protein 1 89420.0 4505531
144 vesicle-trafficking protein SEC22b precursor 24593.2 94429050
145 cytochrome P450 3A4 isoform 2 57255.8 322302351
146 catenin alpha-1 100070.6 55770844
147 signal transducer and activator of transcription 3 isoform 1 88067.3 21618340
148 phosphoglucomutase-1 isoform 1 61448.7 21361621
149 serine--pyruvate aminotransferase 43009.7 4557289
150 mitochondrial carnitine/acylcarnitine carrier protein 32943.5 4557403
151 adipocyte plasma membrane-associated protein 46480.1 24308201
152 translational activator GCN1 292707.0 54607053
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153 7-dehydrocholesterol reductase 54489.1 119943112
154 reticulon-4 isoform A 129930.3 24431935
155 sorbitol dehydrogenase 38324.3 156627571
156 ATP-binding cassette sub-family D member 3 isoform a 75475.5 4506341
157 cytoplasmic dynein 1 heavy chain 1 532406.6 33350932
158 60S ribosomal protein L3 isoform a 46108.6 4506649
159 voltage-dependent anion-selective channel protein 1 30772.3 4507879
160 mitochondrial dicarboxylate carrier 31282.3 20149598
161 myosin-Ia 118399.8 4885503
162 transmembrane emp24 domain-containing protein 9 precursor 27277.2 39725636
163 C4b-binding protein alpha chain precursor 67032.9 4502503
164 serum albumin preproprotein 69366.4 4502027
165 dynamin-1-like protein isoform 1 81876.7 171460914
166 40S ribosomal protein S8 24205.0 4506743
167 vesicle-associated membrane protein-associated protein A isoform 1 32613.3 94721250
168 monoglyceride lipase isoform 1 34292.3 6005786
169 abhydrolase domain-containing protein 14B 22345.5 14249382
170 40S ribosomal protein SA 32853.8 59859885
171 ras-related protein Rab-2A isoform a 23545.4 4506365
172 sodium/potassium-transporting ATPase subunit alpha-1 isoform c 112999.5 237681109
173 poly(rC)-binding protein 1 37497.6 222352151
174 tripeptidyl-peptidase 1 preproprotein 61247.6 5729770
175 elongation factor 1-alpha 2 50469.8 4503475
176 protein disulfide-isomerase A4 precursor 72931.9 4758304
177 PREDICTED: POTE ankyrin domain family member I isoform 2 121281.5 88953571
178 protein transport protein Sec31A isoform 1 133013.8 116256338
179 filamin-B isoform 2 278160.3 105990514
180 cytochrome P450 2A7 isoform 2 precursor 50666.4 15147328
181 lipopolysaccharide-responsive and beige-like anchor protein isoform 2 319105.2 148233596
182 stromal interaction molecule 1 precursor 77422.9 21070997
183 glycerate kinase isoform 1 55252.3 31543063
184 calpain-1 catalytic subunit 81889.4 12408656
185 serotransferrin precursor 77049.5 4557871
186 hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 precursor 56635.1 5031751
187 histone H2A type 1-D 14107.4 10800130
188 retinol dehydrogenase 16 35673.2 150247226
189 L-xylulose reductase isoform 2 25742.7 304571975
190 tubulin beta-8 chain isoform 1 49775.7 42558279
191 cytochrome P450 2C8 isoform b 47785.8 311893309
192 short-chain dehydrogenase/reductase 3 33548.2 31543615
193 UDP-glucuronosyltransferase 2A2 60771.7 333609245
194 ribosome-binding protein 1 108654.8 110611220
195 myosin-11 isoform SM2A 223574.8 13124875
196 junction plakoglobin 81744.3 12056468
197 myosin-14 isoform 3 232008.3 224831241
198 UDP-glucuronosyltransferase 2B28 isoform 2 precursor 38743.0 333033811
199 cytochrome P450 2J2 57610.3 18491008
200 glycine N-acyltransferase isoform a 33924.0 111038137
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201 bromodomain adjacent to zinc finger domain protein 2B 240456.7 94681063
202 cytochrome P450 4A11 59347.5 158937242
203 sepiapterin reductase 28048.3 4507185
204 electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
precursor 68495.0 119703746
205 tubulin beta-2C chain 49830.7 5174735
206 glutathione S-transferase kappa 1 isoform a 25496.7 7705704
207 phosphatidylinositol-binding clathrin assembly protein isoform 1 70754.1 56788366
208 SEC14-like protein 3 46047.9 27923592
209 UDP-glucuronosyltransferase 1-4 precursor 60024.7 6005930
210 sulfotransferase 1A2 34310.4 4507303
211 vigilin isoform b 137969.8 345199283
212 pyruvate kinase isozymes R/L isoform 1 61829.8 10835121
213 OCIA domain-containing protein 2 isoform 1 16953.4 62244044
214 heterogeneous nuclear ribonucleoprotein H2 49263.3 9624998
215 kynurenine 3-monooxygenase 55809.7 187960045
216 fermitin family homolog 2 isoform 3 72396.9 201861823
217 UDP-glucuronosyltransferase 2B15 precursor 61036.0 116517299
218 tubulin alpha-1B chain 50151.3 57013276
219 aldehyde dehydrogenase family 8 member A1 isoform 1 53401.1 12007648
220 transmembrane protein 33 27978.0 224589127
221 ras-related protein Rap-1b isoform 2 16033.3 354459350
222 elongation factor 1-alpha 1 50140.5 4503471
223 ceramide synthase 2 44875.8 31077094
224 cytochrome c oxidase subunit II 25564.8 251831110
225 epiplakin 555623.1 207452735
226 phosphatidate cytidylyltransferase 2 51417.7 20143480
227 uridine 5'-monophosphate synthase 52221.3 4507835
228 arginase-1 isoform 2 34734.7 10947139
229 clathrin interactor 1 isoform 1 70294.4 307078123
230 coatomer subunit gamma-2 97621.8 109134349
231 microsomal glutathione S-transferase 3 16516.2 4758714
232 peroxisomal membrane protein 2 22252.4 8923892
233 hydroxyacid oxidase 1 40924.1 11068137
234 transmembrane protein 205 21197.7 63055043
235 UDP-glucuronosyltransferase 1-9 precursor 59940.7 11276085
236 guanidinoacetate N-methyltransferase isoform a 26318.0 4503909
237 estradiol 17-beta-dehydrogenase 12 34323.9 7705855
238 staphylococcal nuclease domain-containing protein 1 101996.3 77404397
239 UDP-glucuronosyltransferase 2B10 isoform 2 precursor 50688.0 221219059
240 POTE ankyrin domain family member E 121362.7 134133226
241 transmembrane emp24 domain-containing protein 10 precursor 24975.8 98986464
242 POTE ankyrin domain family member F 121443.8 153791352
243 protein disulfide-isomerase A6 precursor 48121.0 5031973
244 mitochondrial import receptor subunit TOM70 67454.4 54607135
245 malectin precursor 32233.6 7661948
246 phosphate carrier protein, mitochondrial isoform b precursor 39958.5 47132595
247 importin subunit beta-1 97169.7 19923142
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248 core histone macro-H2A.1 isoform 1 39183.2 20336746
249 prohibitin 29803.9 4505773
250 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
precursor 50701.3 20070197
251 serum paraoxonase/arylesterase 2 isoform 1 39380.6 66529294
252 nuclear pore membrane glycoprotein 210 precursor 205108.8 27477134
253 transitional endoplasmic reticulum ATPase 89321.3 6005942
254 methyltransferase-like protein 7B precursor 27774.6 164663805
255 aflatoxin B1 aldehyde reductase member 3 37206.2 41152114
256 regulator of microtubule dynamics protein 2 isoform 2 47399.1 283046674
257 catenin beta-1 85496.2 4503131
258 erlin-2 isoform 1 37839.3 6005721
259 60S ribosomal protein L8 28024.4 15431306
260 guanine nucleotide-binding protein subunit beta-2-like 1 35076.5 5174447
261 transmembrane emp24 domain-containing protein 2 precursor 22761.1 5803149
262 beta-soluble NSF attachment protein 33556.8 44917606
263 GTP-binding protein SAR1a 22366.6 217416369
264 cadherin-1 preproprotein 97455.4 4757960
265 glycerol-3-phosphate acyltransferase 1, mitochondrial precursor 93794.2 190358539
266 histone H2B type 1-O 13906.0 16306566
267 heat shock-related 70 kDa protein 2 70020.5 13676857
268 peripherin 53650.5 21264345
269 mitochondrial inner membrane protein isoform 1 83677.3 154354964
270 mitochondrial glutamate carrier 1 34470.0 13375983
271 microsomal triglyceride transfer protein large subunit precursor 99350.6 153285408
272 40S ribosomal protein S3a 29944.7 4506723
273 F-actin-capping protein subunit beta isoform 2 31350.3 330864679
274 lysophospholipid acyltransferase 5 56034.7 42542394
275 tyrosine aminotransferase 50399.2 4507369
276 ras-related protein Rab-1A isoform 1 22677.6 4758988
277 clarin-3 25321.2 22748685
278 enoyl-CoA hydratase domain-containing protein 1 isoform 1 32997.0 157694516
279 glutathione S-transferase A3 25301.5 24430144
280 eukaryotic translation initiation factor 3 subunit L isoform 1 66726.6 7705433
281 26S protease regulatory subunit 10B 45796.7 195539395
282 cytochrome P450 1A2 58407.1 73915100
283 ras-related protein Rab-2B isoform 1 24214.2 21361884
284 dual specificity mitogen-activated protein kinase kinase 4 44287.5 4506889
285 galactokinase 42272.0 4503895
286 hypoxia up-regulated protein 1 precursor 111334.8 5453832
287 PREDICTED: liver carboxylesterase 1-like 27540.5 341916335
288 perilipin-5 50791.1 116292172
289 signal recognition particle receptor subunit beta 29702.0 284795266
290 argininosuccinate synthase 46530.1 16950633
291 plastin-3 isoform 1 70810.6 7549809
292 LETM1 domain-containing protein 1 isoform 1 41790.1 67089165
293 extended synaptotagmin-1 isoform 2 122855.6 14149680
294 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 37330.8 20357529
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295 EH domain-containing protein 3 60886.7 7657056
296 PREDICTED: complement C4-A isoform 1 192843.7 341916194
297 exportin-2 110415.8 29029559
298 ribonuclease inhibitor 49973.3 42822872
299 myosin-Ic isoform c 117906.3 124494240
300 malate dehydrogenase, cytoplasmic isoform 2 36425.9 5174539
301 retinal dehydrogenase 1 54861.5 21361176
302 general vesicular transport factor p115 107906.7 4505541
303 ranBP2-like and GRIP domain-containing protein 4 197286.6 211059431
304 DCC-interacting protein 13-alpha 79663.1 6912242
305 probable ATP-dependent RNA helicase DDX17 isoform 1 80272.0 38201710
306 coatomer subunit delta isoform 1 57210.1 11863154
307 DNA damage-binding protein 1 126967.0 148529014
308 alpha-actinin-1 isoform b 103056.9 4501891
309 EH domain-containing protein 1 60626.4 30240932
310 apolipoprotein E precursor 36153.8 4557325
311 scavenger receptor cysteine-rich type 1 protein M130 isoform a precursor 125450.2 344179110
312 alpha-tocopherol transfer protein-like 38514.9 85861250
313 exocyst complex component 5 81852.4 5730037
314 torsin-1A-interacting protein 1 66248.0 39753957
315 solute carrier organic anion transporter family member 3A1 isoform 2 74372.1 222831573
316 long-chain-fatty-acid--CoA ligase 3 80419.6 42794752
317 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9,
mitochondrial precursor 42509.3 6681764
318 apolipoprotein L2 37092.1 13562090
319 protein DJ-1 19890.9 31543380
320 alkylglycerol monooxygenase 51499.6 51972212
321 heterogeneous nuclear ribonucleoprotein K isoform a 51027.9 14165437
322 transmembrane protein 109 precursor 26209.8 13129092
323 erlin-1 39170.9 154800487
324 OCIA domain-containing protein 1 isoform 1 27626.0 8923427
325 lysosome-associated membrane glycoprotein 1 precursor 44882.1 112380628
326 60S ribosomal protein L18 21634.3 4506607
327 MOSC domain-containing protein 2, mitochondrial precursor 38023.2 31542713
328 ras-related protein Rab-10 22540.8 256222019
329 alcohol dehydrogenase [NADP+] 36572.8 24497577
330 calreticulin precursor 48141.1 4757900
331 enoyl-CoA hydratase, mitochondrial precursor 31387.2 194097323
332 B-cell CLL/lymphoma 9 protein 149289.3 72256200
333 ADP-ribosylation factor GTPase-activating protein 2 isoform 1 56720.0 31543983
334 long-chain-fatty-acid--CoA ligase 6 isoform d 77670.3 327412323
335 cytochrome P450 2A13 56687.2 13699809
336 ras GTPase-activating-like protein IQGAP1 189250.1 4506787
337 splicing factor, proline- and glutamine-rich 76148.9 4826998
338 probable G-protein coupled receptor 110 isoform 1 precursor 101363.9 61743940
339 sorting nexin-29 91253.1 343780938
340 3-keto-steroid reductase 38205.9 7705421
341 3-hydroxyacyl-CoA dehydratase 3 43159.3 117168248
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342 myomegalin isoform 8 254042.9 311771516
343 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 1 68671.3 194018520
344 signal recognition particle receptor subunit alpha isoform 1 69810.8 23308697
345 protocadherin-10 isoform 1 precursor 112935.2 14589916
346 fatty acid-binding protein, liver 14208.3 4557577
347 peroxisomal trans-2-enoyl-CoA reductase 32544.1 19923817
348 prenylcysteine oxidase 1 precursor 56639.8 166795301
349 NEDD4-binding protein 1 100378.1 48928019
350 AP-1 complex subunit gamma-1 isoform b 91351.0 71772942
351 homeobox protein MIXL1 24658.8 13994335
352 peroxiredoxin-1 22110.2 4505591
353 5'-AMP-activated protein kinase subunit beta-2 30302.0 4885561
354 UDP-glucuronosyltransferase 2B11 precursor 61037.9 4507823
355 endoplasmic reticulum-Golgi intermediate compartment protein 1 32592.1 72534712
356 terminal uridylyltransferase 7 isoform 2 144655.2 297374764
357 glyceraldehyde-3-phosphate dehydrogenase 36053.0 7669492
358 heterogeneous nuclear ribonucleoprotein M isoform a 77515.2 14141152
359 membrane-associated progesterone receptor component 2 26169.9 291621647
360 3-mercaptopyruvate sulfurtransferase isoform 2 33178.2 61835204
361 ER lumen protein retaining receptor 2 isoform 1 24421.7 5803050
362 rho-related GTP-binding protein RhoB precursor 22123.3 4757764
363 X-ray repair cross-complementing protein 5 82704.0 10863945
364 serine/threonine-protein kinase OSR1 58021.8 4826878
365 enoyl-CoA delta isomerase 2, mitochondrial isoform 1 40182.8 45643119
366 glutathione S-transferase A5 25721.8 24308514
367 redox-regulatory protein PAMM isoform 1 precursor 25764.0 344925828
368 TRAM adaptor with GOLD domain isoform 2 precursor 21232.8 256985102
369 reticulon-4 isoform C 22395.3 5902016
370 protein disulfide-isomerase A3 precursor 56782.0 21361657
371 serpin H1 precursor 46440.3 333360851
372 AP-2 complex subunit alpha-2 isoform 1 104088.9 338827685
373 beta-2-glycoprotein 1 precursor 38298.0 153266841
374 cytoskeleton-associated protein 4 66022.0 19920317
375 bcl-2-like protein 13 52722.8 45243501
376 transmembrane emp24 domain-containing protein 5 isoform 1 precursor 26004.7 282165814
377 glutamate receptor 1 isoform 1 precursor 101505.4 167001419
378 serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform 4 101006.2 339276044
379 protein kinase C alpha type 76763.6 4506067
380 cytochrome P450 2A6 precursor 56517.1 189339233
381 hemoglobin subunit epsilon 16202.7 4885393
382 leukotriene-B(4) omega-hydroxylase 2 isoform a 59846.4 119220562
383 aspartyl/asparaginyl beta-hydroxylase isoform f 83267.4 258613943
384 coiled-coil domain-containing protein 108 isoform 1 217247.4 83035129
385 ras-related protein Rab-18 22976.9 10880989
386 dyslexia-associated protein KIAA0319-like protein 115656.9 33359221
387 actin-related protein 2 isoform a 45376.2 53692187
388 apolipoprotein C-I precursor 9331.9 4502157
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389 RING finger protein 17 isoform 2 184211.1 297139728
390 dihydropyrimidinase-related protein 4 61877.3 190194363
391 derlin-1 isoform b 26422.7 197927278
392 probable ATP-dependent RNA helicase DDX6 54416.5 164664518
393 60S ribosomal protein L13a 23577.1 6912634
394 ATP synthase subunit gamma, mitochondrial isoform H (heart) precursor 32880.7 4885079
395 DNA mismatch repair protein Mlh3 isoform 2 161019.7 91992160
396 uncharacterized protein C2orf47, mitochondrial precursor 32544.4 239582772
397 beta-actin-like protein 2 42002.9 63055057
398 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
precursor 31629.6 115387094
399 dehydrogenase/reductase SDR family member 7B 35118.8 20149619
400 arylacetamide deacetylase 45733.4 68299767
401 WD repeat-containing protein 62 isoform 2 165952.0 145580610
402 40S ribosomal protein S25 13742.0 4506707
403 obg-like ATPase 1 isoform 1 44743.2 58761500
404 general receptor for phosphoinositides 1-associated scaffold protein 42623.1 32171221
405 HLA class I histocompatibility antigen, A-1 alpha chain precursor 40840.5 24797067
406 peroxisomal bifunctional enzyme isoform 1 79494.4 68989263
407 leukotriene-B(4) omega-hydroxylase 1 precursor 59853.2 13435391
408 cytochrome P450 4A22 59245.5 62952506
409 peroxisomal membrane protein 11B isoform 1 28431.1 4505719
410 nesprin-3 112215.8 145580592
411 lysosome-associated membrane glycoprotein 2 isoform A precursor 44960.5 4504957
412 ras-related protein Rab-5A 23658.5 19923262
413 protein NipSnap homolog 1 isoform 1 33309.7 193211616
414 Down syndrome critical region protein 3 33010.2 5174425
415 acid ceramidase isoform b 46503.3 189011546
416 vitronectin precursor 54305.3 88853069
417 solute carrier family 2, facilitated glucose transporter member 2 57489.2 4557851
418 membrane primary amine oxidase 84621.4 4502119
419 phosphatidylinositol 4-kinase type 2-alpha 54022.0 13559514
420 60S acidic ribosomal protein P1 isoform 1 11513.9 4506669
421 3-ketoacyl-CoA thiolase, peroxisomal isoform a 44291.8 4501853
422 serine hydroxymethyltransferase, cytosolic isoform 1 53082.3 22547186
423 protein PRRC2A 228860.0 149158690
424 T-complex protein 1 subunit delta 57924.0 38455427
425 60S ribosomal protein L7 29225.6 15431301
426 ADP/ATP translocase 1 33064.2 55749577
427 uncharacterized protein C2orf72 30480.5 222418604
428 cyclin-dependent kinase inhibitor 3 isoform 2 19359.1 195927025
429 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 2 65522.6 94557299
430 FAS-associated factor 2 52623.1 24797106
431 fatty acid-binding protein, intestinal 15237.2 194097325
432 alcohol dehydrogenase 1C 39867.4 4501933
433 chromodomain-helicase-DNA-binding protein 8 isoform 2 262344.5 114326455
434 protein transport protein Sec24B isoform a 137416.6 112382212
435 myosin-VI 148712.8 92859701
Page 11
436 E3 ubiquitin-protein ligase TRIM23 isoform alpha 64066.3 4502197
437 zinc finger CCHC domain-containing protein 3 43547.1 29648305
438 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 40450.7 4504041
439 importin subunit alpha-3 57810.5 34485722
440 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-
acetylgalactosaminyltransferase 2 114974.2 71043500
441 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor 59150.1 12548785
442 ras-related protein Rab-1B 22171.0 13569962
443 transmembrane emp24 domain-containing protein 4 precursor 25942.6 33457308
444 ephrin type-A receptor 2 precursor 108265.8 32967311
445 protein OSCP1 isoform 1 43270.6 268370167
446 exportin-7 123906.4 154448892
447 ATP-dependent DNA helicase Q4 133076.5 284005309
448 leiomodin-2 61675.0 150378503
449 structural maintenance of chromosomes protein 2 135655.0 110347420
450 peroxisomal membrane protein PEX14 41236.3 4758896
451 uncharacterized protein C12orf56 isoform 2 53561.4 153791218
452 endothelial lipase precursor 56794.3 5174497
453 6-phosphofructokinase type C isoform 2 85315.5 334191701
454 rho guanine nucleotide exchange factor 2 isoform 1 111542.1 253735775
455 RANBP2-like and GRIP domain-containing protein 1/2 196659.8 262118265
456 zinc finger protein 644 isoform 2 11723.8 41152091
457 isochorismatase domain-containing protein 1 32236.5 103471987
458 X-linked interleukin-1 receptor accessory protein-like 2 precursor 78669.4 11225607
459 exportin-5 136310.3 22748937
460 nucleoprotein TPR 267289.5 114155142
461 cadherin-4 isoform 2 96396.6 356640221
462 charged multivesicular body protein 5 isoform 1 24570.6 189409150
463 heat shock 70 kDa protein 1A/1B 70051.8 194248072
464 DNA repair protein RAD52 homolog 46168.4 109637798
465 BTB/POZ domain-containing protein 18 77931.0 223029436
466 calmodulin-regulated spectrin-associated protein 2 166730.9 44955929
467 protein Muted homolog isoform 1 21609.4 41152237
468 neurolysin, mitochondrial precursor 80651.4 14149738
469 myotubularin-related protein 2 isoform 1 73380.8 44680154
470 MIT domain-containing protein 1 29314.2 20270349
471 proline-rich AKT1 substrate 1 27383.1 148806896
472 splicing factor 3B subunit 1 isoform 1 145829.1 54112117
473 magnesium transporter protein 1 41531.6 215983058
474 dihydropyrimidine dehydrogenase [NADP+] isoform 1 111400.8 119943098
475 cingulin 137055.9 16262452
476 LIM homeobox transcription factor 1-beta isoform 1 44101.8 292494911
477 guanylate cyclase soluble subunit alpha-3 isoform A 77452.1 67763816
478 T-complex protein 1 subunit theta 59620.3 48762932
479 zinc finger protein 878 61539.7 332634996
480 pleckstrin homology domain-containing family G member 2 147968.0 164565408
481 interferon regulatory factor 5 isoform b 56043.8 14249182
482 protein MMS22-like 142319.4 115583683
Page 12
483 numb-like protein 64891.1 10863899
484 epsin-2 isoform b 68481.2 156671215
485 nuclear pore complex protein Nup205 227917.8 57634534
486 microtubule-actin cross-linking factor 1 isoform a 620419.4 33188445
487 thrombospondin-1 precursor 129381.9 40317626
488 dachshund homolog 2 isoform a 65322.5 16876441
489 dynein heavy chain 10, axonemal 514840.2 198442844
490 chloride intracellular channel protein 5 isoform a 46502.3 166197662
491 protein furry homolog 338871.6 117606355
492 trifunctional purine biosynthetic protein adenosine-3 isoform 1 107766.5 209869993
493 probable ATP-dependent RNA helicase DDX60-like 197671.5 149274648
494 ras-related and estrogen-regulated growth inhibitor isoform 1 22607.7 14249704
495 syntaxin-binding protein 4 61661.4 63999048
496 kelch-like protein 6 70358.5 109150407
497 tumor necrosis factor alpha-induced protein 2 72660.9 26051240
498 pericentriolar material 1 protein 228530.8 134142826
499 polyamine-modulated factor 1-binding protein 1 isoform a 117493.1 237858619
500 WD repeat-containing protein 73 41684.8 116235476
501 PR domain zinc finger protein 2 isoform a 188913.7 20336258
502 ankyrin repeat domain-containing protein 31 210813.4 256574792
503 GTP-binding nuclear protein Ran 24422.9 5453555
504 probable E3 ubiquitin-protein ligase MID2 isoform 1 83209.8 223890257
505 aminopeptidase Q 113281.8 194239713
506 uncharacterized protein KIAA1107 149444.1 197245440
507 prestin isoform b 74843.3 45827800
508 sperm-associated antigen 17 251738.6 46240864
509 zinc finger protein 136 62783.4 4507987
510 astrotactin-1 isoform 2 precursor 135081.8 46488921
511 oligodendrocyte transcription factor 2 32384.4 17978475
512 RWD domain-containing protein 2A 33892.7 156523253
513 histone-lysine N-methyltransferase MLL3 541368.5 91718902
514 HLA class II histocompatibility antigen gamma chain isoform b 26398.5 10835071
515 cytochrome b 42717.3 251831119
516 U2 snRNP-associated SURP motif-containing protein 118291.2 122937227
517 kinesin heavy chain isoform 5C 109494.1 4758650
518 60S ribosomal protein L14 23431.7 78000181
519 glutamate-rich WD repeat-containing protein 1 49418.9 237820620
520 docking protein 3 isoform 2 35734.4 221554539
521 lipase maturation factor 2 79697.4 255918129
522 PREDICTED: hypothetical protein LOC100653074 21445.9 341913974
523 fibroblast growth factor-binding protein 2 precursor 24580.9 13994345
524 oxysterol-binding protein-related protein 8 isoform a 101194.8 18079218
525 SET-binding protein isoform a 175005.8 194294554
526 ryanodine receptor 1 isoform 1 565179.0 113204615
527 serine/threonine-protein kinase ATR 301363.9 157266317
528 biliverdin reductase A precursor 33428.3 33589854
529 chromodomain-helicase-DNA-binding protein 6 305409.5 29244924
530 uncharacterized protein C14orf45 61986.5 166295204
Page 13
531 muscle-related coiled-coil protein 41898.9 66472922
532 myosin-binding protein C, fast-type 128070.8 133908641
533 uncharacterized protein C10orf12 137222.6 24431975
534 heterogeneous nuclear ribonucleoprotein L isoform a 64132.4 52632383
535 geminin 23565.0 7705682
536 FERM, RhoGEF and pleckstrin domain-containing protein 2 119887.7 7662310
537 kinesin-like protein KIF24 151902.2 154426306
538 probable G-protein coupled receptor 113 isoform 2 precursor 107019.7 223556014
539 exocyst complex component 6 isoform b 93406.4 62243652
540 mediator of RNA polymerase II transcription subunit 1 168476.9 28559039
541 ubiquitin carboxyl-terminal hydrolase 35 113404.5 148746183
542 phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform 45023.5 5453882
543 alpha-2-macroglobulin precursor 163290.5 66932947
544 matrix metalloproteinase-19 isoform rasi-1 preproprotein 57356.6 4505213
545 RNA-binding protein 42 50413.7 21359951
546 ATP-binding cassette sub-family A member 6 184284.2 27436953
547 leucine-rich repeat-containing protein 59 34930.2 40254924
548 putative tRNA pseudouridine synthase Pus10 60243.8 207113130
549 histone H3-like centromeric protein A isoform a 15990.4 4502775
550 MAGUK p55 subfamily member 5 77293.0 38570142
551 lysine-specific demethylase PHF2 120774.2 117190342
552 SH3 domain-containing protein 21 isoform 2 71237.7 242117948
553 uncharacterized protein KIAA1109 555478.9 150378498
554 methyltransferase-like protein 13 isoform 3 61127.3 55956895
555 transcription elongation regulator 1 isoform 1 123900.1 21327715
556 spatacsin isoform 1 278865.1 93204888
557 ubiquitin-like protein 4A 17776.4 7657667
558 DNA repair protein XRCC4 isoform 2 38286.5 12408647
559 SPS1/STE20-related protein kinase YSK4 isoform 2 57658.6 63998898
560 ras GTPase-activating protein nGAP isoform 1 128556.9 4758808
561 protein kinase C-binding protein 1 isoform b 128370.1 34335266
562 UPF0471 protein C1orf63 33613.1 46309849
563 oligodendrocyte transcription factor 3 29357.4 28411948
564 E3 ubiquitin-protein ligase RNF123 148513.5 37588869
565 bromodomain-containing protein 7 isoform 2 74138.1 41350212
566 uncharacterized protein C20orf177 isoform 1 42051.2 32698752
567 uncharacterized protein C9orf174 197342.3 302565871
568 growth arrest-specific protein 7 isoform b 47679.6 41406078
569 piezo-type mechanosensitive ion channel component 2 318060.9 257900451
570 ras-related protein Rab-8B 23584.0 7706563
571 copper-transporting ATPase 1 163372.3 115529486
572 disintegrin and metalloproteinase domain-containing protein 12 isoform 1
preproprotein 99541.7 73747885
573 kinesin-like protein KIF20A 100277.4 5032013
574 SHC SH2 domain-binding protein 1-like protein 72631.7 93204885
575 complement component C7 precursor 93517.9 45580688
576 DNA nucleotidylexotransferase isoform 1 58535.9 63054850
577 nephrocystin-3 150862.8 34304360
Page 14
578 coiled-coil domain-containing protein 80 precursor 108173.0 41152074
579 PDZ domain-containing protein 6 105647.5 44888833
580 filamin A-interacting protein 1-like isoform 1 130380.8 109659845
581 Golgin subfamily B member 1 376015.7 148596984
582 60S ribosomal protein L5 34362.4 14591909
583 sodium/hydrogen exchanger 9B1 isoform 1 56062.3 66793392
584 gamma-interferon-inducible protein 16 isoform 1 82587.7 330864753
585 G2/mitotic-specific cyclin-B3 isoform 3 157914.8 90669307
586 CD180 antigen precursor 74178.8 167555127
587 Golgi phosphoprotein 3 33810.3 11545859
588 Golgi SNAP receptor complex member 2 isoform B 24583.6 16905520
589 phosphatidylinositol-4-phosphate 5-kinase type-1 beta isoform 2 61036.0 4505817
590 collagen alpha-1(XX) chain 135829.1 112734845
591 calcineurin-binding protein cabin-1 isoform b 240762.4 319738622
592 apoptosis-stimulating of p53 protein 1 119564.7 121114287
593 monoacylglycerol lipase ABHD6 38330.4 189027141
594 uncharacterized protein C1orf141 46134.9 61966795
595 transmembrane protein 2 isoform a 154372.2 7019555
596 dnaJ homolog subfamily C member 16 precursor 90590.8 56687498
Table S3. Identification of proteins associated with LDs of human liver sample 2.
Reference MW Accession
Scan(s) Sp RSp
1 apolipoprotein B-100 precursor 515528.6 105990532
2 long-chain-fatty-acid--CoA ligase 1 77942.9 40807491
3 epoxide hydrolase 1 precursor 52948.5 209862837
4 fatty acid synthase 273423.2 41872631
5 alcohol dehydrogenase 4 40221.5 71565152
6 clathrin heavy chain 1 191612.6 4758012
7 cytochrome P450 2E1 precursor 56848.6 10834998
8 tubulin beta-2A chain 49906.7 4507729
9 bile acyl-CoA synthetase precursor 75384.7 13325057
10 17-beta-hydroxysteroid dehydrogenase 13 isoform B 29604.7 210032112
11 dehydrogenase/reductase SDR family member 1 33908.8 209862901
12 UTP--glucose-1-phosphate uridylyltransferase isoform a 56939.9 48255966
13 NADPH--cytochrome P450 reductase 77047.7 127139033
14 UDP-glucuronosyltransferase 2B7 precursor 60720.3 190194389
Page 15
15 ATP synthase subunit alpha, mitochondrial precursor 59750.3 4757810
16 lanosterol synthase isoform 2 82198.1 224177556
17 spectrin beta chain, brain 1 isoform 1 274606.5 112382250
18 dimethylaniline monooxygenase [N-oxide-forming] 3 60033.2 50541961
19 NADH-cytochrome b5 reductase 3 isoform 2 31628.5 193794826
20 tubulin alpha-1A chain 50135.3 17986283
21 dimethylaniline monooxygenase [N-oxide-forming] 5 isoform 1 60220.2 221316672
22 methyltransferase-like protein 7A precursor 28318.9 89145417
23 ras GTPase-activating-like protein IQGAP2 180577.0 116089337
24 amine oxidase [flavin-containing] B 58762.6 38202207
25 trifunctional enzyme subunit alpha, mitochondrial precursor 82999.1 20127408
26 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform c 116037.4 170295797
27 cytochrome P450 2C19 precursor 55944.8 4503219
28 peroxisomal multifunctional enzyme type 2 isoform 1 83024.9 313482810
29 perilipin-2 48075.1 34577059
30 cytochrome P450 2C9 precursor 55627.6 13699818
31 acetyl-CoA carboxylase 2 precursor 276537.6 134142062
32 calcium-binding mitochondrial carrier protein Aralar2 isoform 2 74175.1 7657581
33 fatty aldehyde dehydrogenase isoform 1 57669.1 73466520
34 ATP-binding cassette sub-family D member 3 isoform a 75475.5 4506341
35 peroxisomal bifunctional enzyme isoform 2 69153.5 261878539
36 cytochrome P450 2A7 isoform 2 precursor 50666.4 15147328
37 serum albumin preproprotein 69366.4 4502027
38 very long-chain acyl-CoA synthetase isoform 1 70311.8 227499619
39 UDP-glucuronosyltransferase 2B4 precursor 60512.1 149944509
Page 16
40 protein ERGIC-53 precursor 57548.6 5031873
41 estradiol 17-beta-dehydrogenase 11 32935.6 142976729
42 ATP synthase subunit beta, mitochondrial precursor 56559.5 32189394
43 endoplasmin precursor 92468.2 4507677
44 monoglyceride lipase isoform 1 34292.3 6005786
45 perilipin-3 isoform 1 47074.7 255958282
46 apolipoprotein A-I preproprotein 30777.6 4557321
47 coatomer subunit alpha isoform 2 138344.7 148536853
48 calnexin precursor 67567.8 10716563
49 arylacetamide deacetylase 45733.4 68299767
50 UDP-glucuronosyltransferase 2B15 precursor 61036.0 116517299
51 protein disulfide-isomerase precursor 57115.9 20070125
52 plectin isoform 1e 513705.9 41322908
53 synaptic vesicle membrane protein VAT-1 homolog 41920.0 18379349
54 cullin-associated NEDD8-dissociated protein 1 136374.7 21361794
55 liver carboxylesterase 1 isoform c precursor 62392.5 68508957
56 spectrin alpha chain, brain isoform 1 285091.3 194595509
57 cytoplasmic dynein 1 heavy chain 1 532406.6 33350932
58 apolipoprotein E precursor 36153.8 4557325
59 tubulin beta chain 49670.5 29788785
60 sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 41900.0 8393516
61 microsomal glutathione S-transferase 1 17598.6 9945306
62 NAD(P) transhydrogenase, mitochondrial precursor 113894.8 122939155
63 serum paraoxonase/arylesterase 1 precursor 39731.0 19923106
64 cytochrome P450 2C8 isoform b 47785.8 311893309
65 cytochrome P450 1A2 58407.1 73915100
66 78 kDa glucose-regulated protein precursor 72332.5 16507237
67 annexin A6 isoform 1 75872.8 71773329
Page 17
68 adipocyte plasma membrane-associated protein 46480.1 24308201
69 PREDICTED: liver carboxylesterase 1-like 27540.5 341916335
70 redox-regulatory protein PAMM isoform 1 precursor 25764.0 344925828
71 retinol dehydrogenase 16 35673.2 150247226
72 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48
kDa subunit precursor 50701.3 20070197
73 vimentin 53651.3 62414289
74 ATP-dependent RNA helicase DDX3X isoform 2 73156.0 301171467
75 voltage-dependent anion-selective channel protein 1 30772.3 4507879
76 cytochrome P450 3A7 57525.2 262290932
77 very long-chain specific acyl-CoA dehydrogenase, mitochondrial
isoform 2 precursor 68058.1 76496475
78 C-1-tetrahydrofolate synthase, cytoplasmic 101530.5 222136639
79 MOSC domain-containing protein 2, mitochondrial precursor 38023.2 31542713
80 probable saccharopine dehydrogenase 47151.1 55770836
81 cytochrome P450 2A6 precursor 56517.1 189339233
82 carnitine O-palmitoyltransferase 1, liver isoform isoform 1 88367.1 73623030
83 3-hydroxyacyl-CoA dehydratase 3 43159.3 117168248
84 delta(24)-sterol reductase precursor 60100.9 13375618
85 ATP-binding cassette sub-family A member 6 184284.2 27436953
86 histone H4 11367.3 4504301
87 bile salt sulfotransferase 33779.6 29540545
88 amine oxidase [flavin-containing] A 59681.3 4557735
89 alcohol dehydrogenase 1B 39835.3 34577061
90 perilipin-1 55990.0 223718203
91 alpha-actinin-4 104853.3 12025678
92 succinate dehydrogenase [ubiquinone] flavoprotein subunit,
mitochondrial 72691.1 156416003
93 elongation factor 1-alpha 2 50469.8 4503475
94 aldehyde dehydrogenase family 8 member A1 isoform 3 48035.6 301500698
Page 18
95 protein diaphanous homolog 1 isoform 1 141346.4 119395758
96 dolichyl-diphosphooligosaccharide--protein glycosyltransferase
subunit 1 precursor 68569.0 4506675
97 estradiol 17-beta-dehydrogenase 12 34323.9 7705855
98 ribosome-binding protein 1 108654.8 110611220
99 17-beta-hydroxysteroid dehydrogenase type 6 35965.5 19743808
100 dolichyl-diphosphooligosaccharide--protein glycosyltransferase
subunit 2 isoform 1 precursor 69283.5 35493916
101 trifunctional enzyme subunit beta, mitochondrial precursor 51294.1 4504327
102 programmed cell death 6-interacting protein isoform 1 96022.6 22027538
103 myosin-Ic isoform c 117906.3 124494240
104 elongation factor 2 95337.6 4503483
105 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP
lyase (cyclizing) 58946.8 20149621
106 myosin-9 226529.8 12667788
107 prenylcysteine oxidase 1 precursor 56639.8 166795301
108 SEC14-like protein 2 isoform 1 46145.0 7110715
109 D-3-phosphoglycerate dehydrogenase 56650.2 23308577
110 long-chain-fatty-acid--CoA ligase 5 isoform a 82262.5 42794756
111 serum paraoxonase/lactonase 3 39607.2 29788996
112 glutamate dehydrogenase 2, mitochondrial precursor 61433.6 31377775
113 sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform b 114756.1 24638454
114 PREDICTED: POTE ankyrin domain family member I isoform 2 121281.5 88953571
115 retinol dehydrogenase 10 38087.3 25282469
116 glycerol-3-phosphate acyltransferase 1, mitochondrial precursor 93794.2 190358539
117 transferrin receptor protein 2 isoform 2 69617.1 332309171
118 cytochrome P450 2C18 isoform 1 precursor 55710.4 13699816
119 alpha-mannosidase 2 131139.6 51477714
Page 19
120 histone H2B type 1-C/E/F/G/I 13906.0 4504271
121 17-beta-hydroxysteroid dehydrogenase 13 isoform A 33655.2 210032110
122 cytochrome P450 4F11 precursor 60145.5 193083178
123 protein transport protein Sec24A isoform 1 119748.6 116174780
124 dehydrogenase/reductase SDR family member 7 precursor 38298.5 7706318
125 vitronectin precursor 54305.3 88853069
126 UDP-glucuronosyltransferase 1-6 isoform 1 precursor 60750.4 45827765
127 cytochrome P450 2A13 56687.2 13699809
128 Golgi apparatus protein 1 isoform 2 precursor 135994.8 224586815
129 calcium-binding mitochondrial carrier protein Aralar1 74761.4 21361103
130 perilipin-4 134430.4 122937195
131 methyltransferase-like protein 7B precursor 27774.6 164663805
132 mitochondrial carrier homolog 2 33330.7 7657347
133 histone H2A type 1-D 14107.4 10800130
134 actin, cytoplasmic 1 41736.5 4501885
135 7-dehydrocholesterol reductase 54489.1 119943112
136 peroxisomal multifunctional enzyme type 2 isoform 2 79685.9 4504505
137 myosin-Ib isoform 2 124949.7 44889481
138 reticulon-4 isoform A 129930.3 24431935
139 tripeptidyl-peptidase 1 preproprotein 61247.6 5729770
140 prohibitin-2 isoform 1 33296.1 221307584
141 cytochrome b-c1 complex subunit 1, mitochondrial precursor 52645.5 46593007
142 coatomer subunit beta 107141.5 7705369
143 prolow-density lipoprotein receptor-related protein 1 precursor 504608.8 126012562
144 ras-related protein Rab-14 23896.8 19923483
145 60S ribosomal protein L18 21634.3 4506607
146 kynurenine 3-monooxygenase 55809.7 187960045
147 cytochrome P450 4A22 59245.5 62952506
148 ras-related protein Rab-7a 23489.6 34147513
149 importin-5 125544.3 24797086
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150 UDP-glucuronosyltransferase 1-4 precursor 60024.7 6005930
151 40S ribosomal protein SA 32853.8 59859885
152 ras-related protein Rap-1b isoform 2 16033.3 354459350
153 ATP synthase subunit O, mitochondrial precursor 23277.2 4502303
154 guanine nucleotide-binding protein subunit beta-2-like 1 35076.5 5174447
155 transmembrane 9 superfamily member 2 precursor 75775.3 4758874
156 long-chain-fatty-acid--CoA ligase 3 80419.6 42794752
157 cathepsin D preproprotein 44552.0 4503143
158 apolipoprotein(a) precursor 226543.6 116292750
159 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform a 109255.5 28373103
160 hemoglobin subunit delta 16055.4 4504351
161 60 kDa heat shock protein, mitochondrial 61054.2 31542947
162 nodal modulator 1 precursor 134323.0 51944953
163 hemoglobin subunit beta 15998.3 4504349
164 cytochrome P450 4A11 59347.5 158937242
165 cytochrome P450 2A7 isoform 1 precursor 56424.8 15147330
166 ras-related protein Rab-2B isoform 2 19005.1 254281345
167 peroxisomal membrane protein 2 22252.4 8923892
168 melanoma inhibitory activity protein 3 precursor 213699.7 122891870
169 corticosteroid 11-beta-dehydrogenase isozyme 1 32400.8 5031765
170 coatomer subunit gamma 97717.7 11559929
171 cytochrome b5 isoform 1 15330.0 41281768
172 receptor expression-enhancing protein 6 20733.0 19923919
173 erlin-2 isoform 1 37839.3 6005721
174 epoxide hydrolase 2 62615.4 27597073
175 protein disulfide-isomerase A4 precursor 72931.9 4758304
176 transmembrane protein 205 21197.7 63055043
Page 21
177 leukotriene-B(4) omega-hydroxylase 1 precursor 59853.2 13435391
178 signal transducer and activator of transcription 3 isoform 1 88067.3 21618340
179 extended synaptotagmin-1 isoform 2 122855.6 14149680
180 alpha-actinin-1 isoform b 103056.9 4501891
181 lysophospholipid acyltransferase 5 56034.7 42542394
182 Golgi integral membrane protein 4 81879.8 7657138
183 cytochrome P450 3A5 isoform 1 57108.3 4503231
184 abhydrolase domain-containing protein 14B 22345.5 14249382
185 phosphate carrier protein, mitochondrial isoform b precursor 39958.5 47132595
186 exportin-1 123385.0 4507943
187 apoptosis-inducing factor 1, mitochondrial isoform 2 precursor 66294.3 22202629
188 tubulin alpha-1B chain 50151.3 57013276
189 general vesicular transport factor p115 107906.7 4505541
190 endoplasmic reticulum-Golgi intermediate compartment protein 1 32592.1 72534712
191 dynamin-1-like protein isoform 1 81876.7 171460914
192 uncharacterized protein C9orf174 197342.3 302565871
193 vesicular integral-membrane protein VIP36 precursor 40228.4 5803023
194 protein transport protein Sec23A 86160.3 38202214
195 beta-galactoside alpha-2,6-sialyltransferase 1 isoform a 46604.3 27765091
196 beta-2-glycoprotein 1 precursor 38298.0 153266841
197 UDP-glucuronosyltransferase 2B10 isoform 2 precursor 50688.0 221219059
198 L-xylulose reductase isoform 2 25742.7 304571975
199 clusterin preproprotein 52494.3 355594753
200 reticulon-4 isoform C 22395.3 5902016
201 acid ceramidase isoform b 46503.3 189011546
202 cytochrome b5 type B 16694.4 83921614
203 calpain-1 catalytic subunit 81889.4 12408656
204 ADP/ATP translocase 2 32852.0 156071459
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205 E3 UFM1-protein ligase 1 89594.6 24308039
206 voltage-dependent anion-selective channel protein 3 isoform 2 30789.6 208879465
207 vacuolar protein sorting-associated protein 13C isoform 1B 403082.1 66348091
208 protein disulfide-isomerase A6 precursor 48121.0 5031973
209 Golgi-specific brefeldin A-resistance guanine nucleotide exchange
factor 1 isoform 1 206443.7 4758416
210 60S ribosomal protein L7 29225.6 15431301
211 cytochrome P450 4F8 precursor 59994.3 6005737
212 immunoglobulin-like and fibronectin type III domain-containing
protein 1 383803.9 257196151
213 cytochrome b-c1 complex subunit 2, mitochondrial precursor 48442.7 50592988
214 poly [ADP-ribose] polymerase 14 202798.2 154813199
215 RIB43A-like with coiled-coils protein 1 isoform 1 44014.7 72534784
216 electron transfer flavoprotein-ubiquinone oxidoreductase,
mitochondrial precursor 68495.0 119703746
217 erythrocyte band 7 integral membrane protein isoform a 31730.6 38016911
218 membrane-associated progesterone receptor component 1 21671.0 5729875
219 tubulin beta-2C chain 49830.7 5174735
220 apolipoprotein C-III precursor 10852.2 4557323
221 estradiol 17-beta-dehydrogenase 2 42784.9 4504503
222 hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1
precursor 56635.1 5031751
223 protein PRRC1 46700.9 18677735
224 POTE ankyrin domain family member F 121443.8 153791352
225 AP-2 complex subunit beta isoform b 104551.9 4557469
226 plasminogen isoform 1 precursor 90568.6 4505881
227 40S ribosomal protein S5 22876.3 13904870
228 heat shock protein HSP 90-alpha isoform 1 98160.4 153792590
Page 23
229 heterogeneous nuclear ribonucleoprotein U isoform a 90584.0 74136883
230 sorbitol dehydrogenase 38324.3 156627571
231 surfeit locus protein 4 30393.8 19557691
232 UDP-N-acetylglucosamine transporter 35984.2 6912668
233 coatomer subunit gamma-2 97621.8 109134349
234 sec1 family domain-containing protein 1 isoform a 72379.4 33469966
235 leucine-rich repeat-containing protein 59 34930.2 40254924
236 heterogeneous nuclear ribonucleoprotein H2 49263.3 9624998
237 retinol dehydrogenase 11 isoform 1 precursor 35386.0 166795268
238 ATP-binding cassette sub-family D member 1 82936.5 7262393
239 dual specificity mitogen-activated protein kinase kinase 2 44423.9 13489054
240 60S ribosomal protein L4 47697.0 16579885
241 sulfotransferase 1A2 34310.4 4507303
242 40S ribosomal protein S3a 29944.7 4506723
243 ras-related protein Rab-8A 23668.1 16933567
244 phosphoglucomutase-1 isoform 1 61448.7 21361621
245 aldehyde oxidase 147916.9 71773480
246 heat shock protein HSP 90-beta 83263.6 20149594
247 transmembrane protein 33 27978.0 224589127
248 myosin-Ia 118399.8 4885503
249 60S ribosomal protein L19 23465.8 4506609
250 microsomal glutathione S-transferase 3 16516.2 4758714
251 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10,
mitochondrial precursor 40750.3 4758768
252 40S ribosomal protein S3 26688.1 15718687
253 catechol O-methyltransferase isoform MB-COMT 30036.9 4502969
254 alpha-soluble NSF attachment protein 33232.5 47933379
255 junction plakoglobin 81744.3 12056468
256 probable ATP-dependent RNA helicase DDX5 69147.6 4758138
257 40S ribosomal protein S8 24205.0 4506743
Page 24
258 mevalonate kinase 42450.6 4557769
259 voltage-dependent anion-selective channel protein 2 isoform 1 33371.4 296317337
260 TRAM adaptor with GOLD domain isoform 2 precursor 21232.8 256985102
261 non-specific lipid-transfer protein isoform 1 proprotein 58993.3 19923233
262 E3 ubiquitin-protein ligase MARCH5 31231.5 8923415
263 heterogeneous nuclear ribonucleoprotein F 45671.6 4826760
264 long-chain-fatty-acid--CoA ligase 6 isoform d 77670.3 327412323
265 multidrug resistance-associated protein 6 isoform 1 164872.8 190343023
266 acetolactate synthase-like protein 67867.3 21361361
267 catenin alpha-1 100070.6 55770844
268 cytochrome P450 3A4 isoform 2 57255.8 322302351
269 vesicle-associated membrane protein-associated protein B/C isoform
1 27228.2 4759302
270 UDP-glucuronosyltransferase 1-9 precursor 59940.7 11276085
271 formimidoyltransferase-cyclodeaminase 58926.2 11140815
272 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform a
precursor 165648.8 169790915
273 26S proteasome non-ATPase regulatory subunit 5 56195.4 4826952
274 vesicle transport protein GOT1B 15425.6 7705636
275 UDP-glucuronosyltransferase 2B11 precursor 61037.9 4507823
276 aldehyde dehydrogenase family 8 member A1 isoform 1 53401.1 12007648
277 60S ribosomal protein L23 14865.4 4506605
278 eukaryotic initiation factor 4A-II 46402.0 83700235
279 3-ketoacyl-CoA thiolase, mitochondrial 41923.9 167614485
280 C4b-binding protein alpha chain precursor 67032.9 4502503
281 hemoglobin subunit alpha 15257.4 4504345
Page 25
282 N-terminal kinase-like protein isoform A 89630.9 115430241
283 protein MON2 homolog 190356.9 114326552
284 mannosyl-oligosaccharide glucosidase isoform 1 91917.0 149999606
285 lanosterol synthase isoform 1 83308.3 47933395
286 ras-related protein Rab-18 22976.9 10880989
287 epidermal growth factor receptor kinase substrate 8-like protein 2 80620.2 21264616
288 neutral cholesterol ester hydrolase 1 isoform c 31167.6 226423950
289 14-3-3 protein epsilon 29173.7 5803225
290 acetyl-CoA acetyltransferase, mitochondrial precursor 45199.3 4557237
291 3-ketoacyl-CoA thiolase, peroxisomal isoform a 44291.8 4501853
292 transmembrane 9 superfamily member 1 isoform b precursor 55250.5 62460635
293 asialoglycoprotein receptor 2 isoform a 35191.1 4502253
294 GTP-binding protein SAR1a 22366.6 217416369
295 ras-related protein Rab-10 22540.8 256222019
296 cutaneous T-cell lymphoma-associated antigen 9 87952.4 224586773
297 inositol 1,4,5-trisphosphate receptor type 2 308061.1 95147335
298 malectin precursor 32233.6 7661948
299 elongation factor 1-alpha 1 50140.5 4503471
300 ATP synthase subunit gamma, mitochondrial isoform H (heart)
precursor 32880.7 4885079
301 40S ribosomal protein S15a 14839.4 71772415
302 galectin-4 35940.9 5453712
303 transitional endoplasmic reticulum ATPase 89321.3 6005942
304 thromboxane-A synthase isoform 1 60649.2 195972898
305 apolipoprotein O-like precursor 29158.7 116812610
306 tubulin alpha chain-like 3 isoform 1 49908.5 13376181
307 S-adenosylmethionine synthase isoform type-1 43647.7 4557737
308 annexin A4 36084.8 4502105
Page 26
309 acyl-CoA dehydrogenase family member 11 87263.9 38505218
310 cytoskeleton-associated protein 4 66022.0 19920317
311 leukotriene-B(4) omega-hydroxylase 2 isoform a 59846.4 119220562
312 HLA class I histocompatibility antigen, A-1 alpha chain precursor 40840.5 24797067
313 leukotriene-B(4) omega-hydroxylase 2 isoform b 59738.4 312836833
314 succinate dehydrogenase [ubiquinone] iron-sulfur subunit,
mitochondrial precursor 31629.6 115387094
315 histone H2B type 1-O 13906.0 16306566
316 dedicator of cytokinesis protein 7 239419.7 54112429
317 oligosaccharyltransferase complex subunit OSTC 16829.2 24308271
318 docking protein 1 isoform 1 52391.5 4503357
319 lanosterol 14-alpha demethylase isoform 1 precursor 57278.0 4503243
320 protein LYRIC 63836.5 223555917
321 translational activator GCN1 292707.0 54607053
322 histone H1.0 20862.8 4885371
323 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform
1 precursor 70729.6 66346721
324 ras-related protein Rap-1A 20987.1 4506413
325 fatty acid-binding protein, liver 14208.3 4557577
326 dynamin-like 120 kDa protein, mitochondrial isoform 1 111629.9 224831243
327 asialoglycoprotein receptor 1 isoform b 29143.8 308387363
328 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 37330.8 20357529
329 cytochrome P450 3A43 isoform 2 57669.5 16933533
330 sterol 26-hydroxylase, mitochondrial precursor 60234.4 4503211
331 sodium- and chloride-dependent glycine transporter 1 isoform 3 70582.4 67782317
332 peroxisomal trans-2-enoyl-CoA reductase 32544.1 19923817
333 MAP kinase-activating death domain protein isoform g 175915.5 18860873
Page 27
334 prohibitin 29803.9 4505773
335 carnitine O-palmitoyltransferase 2, mitochondrial precursor 73776.6 4503023
336 15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 28977.1 31542939
337 D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 38156.9 44680133
338 thioredoxin-related transmembrane protein 1 precursor 31791.0 151101292
339 erlin-1 39170.9 154800487
340 histone H3.1 15404.0 4504281
341 serine/threonine-protein kinase OSR1 58021.8 4826878
342 NADH-cytochrome b5 reductase 1 34094.6 49574502
343 40S ribosomal protein S2 31324.2 15055539
344 ATP-binding cassette sub-family A member 1 254298.9 21536376
345 proteasome activator complex subunit 2 27401.4 30410792
346 RPS10-NUDT3 protein 33140.6 321117084
347 rho-related GTP-binding protein RhoB precursor 22123.3 4757764
348 bax inhibitor 1 isoform 1 26537.6 148746209
349 atlastin-3 60541.6 45827806
350 importin subunit beta-1 97169.7 19923142
351 multivesicular body subunit 12B isoform 1 35619.4 58761488
352 type I iodothyronine deiodinase isoform a 28774.2 4557522
353 26S protease regulatory subunit 10B 45796.7 195539395
354 desmoplakin isoform I 331771.4 58530840
355 serine/threonine-protein phosphatase PGAM5, mitochondrial
isoform 1 32004.2 281604136
356 transmembrane emp24 domain-containing protein 9 precursor 27277.2 39725636
357 2,4-dienoyl-CoA reductase, mitochondrial precursor 36067.5 4503301
358 dolichyl-diphosphooligosaccharide--protein glycosyltransferase
subunit DAD1 12496.6 4503253
359 peroxisomal bifunctional enzyme isoform 1 79494.4 68989263
360 phosphoinositide 3-kinase adapter protein 1 90397.3 45505139
361 stomatin-like protein 2 38533.8 7305503
Page 28
362 trifunctional purine biosynthetic protein adenosine-3 isoform 1 107766.5 209869993
363 UDP-glucuronosyltransferase 2B28 isoform 2 precursor 38743.0 333033811
364 UPF0554 protein C2orf43 37318.3 11345458
365 puromycin-sensitive aminopeptidase 103275.6 158937236
366 calreticulin precursor 48141.1 4757900
367 palmitoyl-protein thioesterase 1 isoform 1 precursor 34193.3 4506031
368 ras-related protein Rap-1b isoform 4 15355.6 354459356
369 brefeldin A-inhibited guanine nucleotide-exchange protein 2 202036.4 150417986
370 fibrinogen gamma chain isoform gamma-A precursor 49496.2 70906437
371 3-keto-steroid reductase 38205.9 7705421
372 vacuolar protein sorting-associated protein 13A isoform C 355859.0 66346672
373 cytochrome c oxidase subunit 7A2, mitochondrial precursor 12843.9 262118227
374 protein FAM5B precursor 89004.1 23943866
375 polypeptide N-acetylgalactosaminyltransferase 2 precursor 64732.4 4758412
376 alpha-tocopherol transfer protein 31749.4 4507723
377 translocon-associated protein subunit alpha precursor 32235.1 169404009
378 UBX domain-containing protein 4 56777.2 24307965
379 tudor domain-containing protein 6 isoform 1 236514.7 58197558
380 probable N-acetyltransferase 8 25618.9 117190517
381 arginase-1 isoform 2 34734.7 10947139
382 translocation protein SEC63 homolog 87996.4 6005872
383 pre-mRNA cleavage complex 2 protein Pcf11 173048.7 33620745
384 Golgin subfamily B member 1 376015.7 148596984
385 ras-related protein Rab-11A isoform 1 24393.3 4758984
386 protein NipSnap homolog 1 isoform 1 33309.7 193211616
387 talin-1 269764.4 223029410
388 signal transducer and activator of transcription 6 isoform 2 81747.4 296010868
Page 29
389 sorting nexin-14 isoform a 110180.9 24797145
390 ragulator complex protein LAMTOR1 17744.7 8923579
391 alpha-1,3-mannosyl-glycoprotein 2-beta-N-
acetylglucosaminyltransferase 50878.0 167857778
392 40S ribosomal protein S7 22126.7 4506741
393 cathepsin B preproprotein 37821.4 4503139
394 lysosome-associated membrane glycoprotein 2 isoform A precursor 44960.5 4504957
395 60S acidic ribosomal protein P0 34273.3 16933546
396 Golgi pH regulator B 52916.7 7706704
397 coiled-coil domain-containing protein 47 precursor 55873.5 171906582
398 60S ribosomal protein L18a 20762.2 11415026
399 apolipoprotein L3 isoform 1 44277.9 22035646
400 DNA ligase 4 103970.1 23199993
401 hemoglobin subunit epsilon 16202.7 4885393
402 5'-AMP-activated protein kinase subunit beta-2 30302.0 4885561
403 proteasome activator complex subunit 1 isoform 1 28722.9 5453990
404 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase 58068.1 166362724
405 signal peptidase complex catalytic subunit SEC11A 20625.2 7657609
406 conserved oligomeric Golgi complex subunit 7 86343.4 23957690
407 neuropathy target esterase isoform b 146214.6 116256487
408 probable E3 ubiquitin-protein ligase HERC6 isoform 1 115125.5 61563742
409 torsin-1A-interacting protein 1 66248.0 39753957
410 mitogen-activated protein kinase kinase kinase 15 147436.0 282847398
411 lipopolysaccharide-responsive and beige-like anchor protein isoform
2 319105.2 148233596
412 tyrosine-protein kinase BAZ1B 170901.2 14670392
413 signal recognition particle receptor subunit alpha isoform 1 69810.8 23308697
Page 30
414 RANBP2-like and GRIP domain-containing protein 8 198990.7 256600210
415 cytochrome c oxidase subunit II 25564.8 251831110
416 transient receptor potential cation channel subfamily M member 2 171224.5 4507689
417 serum paraoxonase/arylesterase 2 isoform 1 39380.6 66529294
418 serine beta-lactamase-like protein LACTB, mitochondrial isoform a 60693.3 26051231
419 neuron navigator 3 253019.3 120953251
420 mesoderm induction early response protein 2 59943.9 45267839
421 tricarboxylate transport protein, mitochondrial precursor 34012.4 21389315
422 alcohol dehydrogenase 1C 39867.4 4501933
423 HLA class I histocompatibility antigen, Cw-1 alpha chain precursor 40648.3 52630342
424 protein transport protein Sec24B isoform a 137416.6 112382212
425 E3 ubiquitin-protein ligase TRIM23 isoform alpha 64066.3 4502197
426 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 40450.7 4504041
427 ras GTPase-activating-like protein IQGAP1 189250.1 4506787
428 chromosome-associated kinesin KIF4A 139880.1 116686122
429 gamma-parvin 37485.0 11545879
430 centrosomal protein of 128 kDa 128014.2 64085252
431 gamma-aminobutyric acid receptor subunit beta-2 isoform 1
precursor 59150.1 12548785
432 ribonuclease P protein subunit p40 41833.7 55743132
433 enoyl-CoA hydratase domain-containing protein 1 isoform 1 32997.0 157694516
434 dynein heavy chain 14, axonemal isoform 1 518563.2 223555935
435 zinc finger and BTB domain-containing protein 1 isoform 2 73682.1 182509178
436 inositol 1,4,5-trisphosphate receptor type 1 isoform 1 308536.7 269954690
437 myosin-14 isoform 3 232008.3 224831241
Page 31
438 transmembrane protein 109 precursor 26209.8 13129092
439 cystatin-9-like precursor 17275.7 18104940
440 testis-expressed sequence 2 protein 125997.8 38679909
441 cytochrome P450 4F22 61957.9 158138530
442 NEDD8 ultimate buster 1 isoform 2 71921.4 343403796
443 A disintegrin and metalloproteinase with thrombospondin motifs 20
preproprotein 214718.3 124430557
444 annexin A3 36375.0 4826643
445 heat shock 70 kDa protein 1A/1B 70051.8 194248072
446 outer dense fiber protein 2 isoform 1 103066.6 310750400
447 titin isoform N2-B 2992860.0 291045223
448 cadherin-4 isoform 2 96396.6 356640221
449 killer cell lectin-like receptor subfamily F member 1 26562.4 7705574
450 uncharacterized protein KIAA2026 228084.7 148612838
451 guanylate cyclase soluble subunit alpha-3 isoform A 77452.1 67763816
452 ATPase family AAA domain-containing protein 5 207568.0 26080431
453 coiled-coil domain-containing protein 164 87133.6 217416374
454 DNA-binding protein RFXANK isoform a 28102.1 4506499
455 olfactory receptor 5B3 35257.5 53793671
456 oxidoreductase HTATIP2 isoform b 27048.8 148728164
457 myotilin isoform a 55394.8 5803106
458 charged multivesicular body protein 5 isoform 1 24570.6 189409150
459 muskelin isoform 1 82404.6 223890246
460 serine/threonine-protein kinase pim-2 34190.1 42821112
461 nucleoprotein TPR 267289.5 114155142
462 POU domain, class 5, transcription factor 2 36050.9 23463326
463 plexin-B1 precursor 232295.2 40254442
464 MIT domain-containing protein 1 29314.2 20270349
465 exportin-5 136310.3 22748937
466 aminopeptidase Q 113281.8 194239713
467 prelamin-A/C isoform 1 precursor 74139.0 27436946
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468 WD repeat-containing protein 88 52620.7 102470001
469 microtubule-actin cross-linking factor 1 isoform a 620419.4 33188445
470 DNA repair protein RAD52 homolog 46168.4 109637798
471 canalicular multispecific organic anion transporter 2 isoform 2 64631.5 221316556
472 receptor-type tyrosine-protein phosphatase delta isoform 1 precursor 214757.5 4506309
473 gamma-tubulin complex component 2 102533.3 5729840
474 filamin-A-interacting protein 1 138108.1 31542634
475 calmodulin-regulated spectrin-associated protein 2 166730.9 44955929
476 cytochrome P450 2B6 precursor 56278.0 7949031
477 ankyrin-3 isoform 1 480407.6 32967601
478 transmembrane emp24 domain-containing protein 4 precursor 25942.6 33457308
479 ankyrin repeat domain-containing protein 34C 58256.0 226437606
480 beta-defensin 116 precursor 11544.3 83582800
481 leiomodin-2 61675.0 150378503
482 cyclic nucleotide-gated cation channel alpha-3 isoform 1 78837.6 4502917
483 tripartite motif-containing protein 65 57353.1 38679905
484 oxidation resistance protein 1 isoform 3 97969.4 309384265
485 helicase SRCAP 343551.4 146219843
486 centromere protein J 152999.0 130980075
487 pleckstrin homology domain-containing family G member 5 isoform
c 117450.4 111154078
488 DENN domain-containing protein 4B 163845.5 148922920
489 syntaxin-binding protein 4 61661.4 63999048
490 FH1/FH2 domain-containing protein 3 160802.3 58331242
491 polycomb protein SCMH1 isoform f 52908.0 288557339
492 potassium/sodium hyperpolarization-activated cyclic nucleotide-
gated channel 2 96950.0 156071470
Page 33
493 potassium voltage-gated channel subfamily G member 2 51239.3 6912444
494 histone deacetylase 9 isoform 4 117206.8 30795202
495 DNA repair protein REV1 isoform 1 138247.1 7706681
496 disabled homolog 2 isoform 1 82447.3 148491082
497 aldose reductase 35853.2 4502049
498 insulin receptor-related protein precursor 143719.0 31657140
499 integrin alpha-4 precursor 114898.8 67191027
500 6-phosphofructokinase type C isoform 2 85315.5 334191701
501 serotransferrin precursor 77049.5 4557871
502 sperm protein associated with the nucleus on the X chromosome N4 11168.3 57528117
503 NEDD8-MDP1 protein 22027.0 315259111
504 fructose-bisphosphate aldolase B 39472.8 40354205
505 proline-rich protein 12 211041.2 153792074
506 methylmalonate-semialdehyde dehydrogenase [acylating],
mitochondrial precursor 57839.4 11095441
507 arf-GAP with SH3 domain, ANK repeat and PH domain-containing
protein 2 isoform a 111649.9 4502249
508 ESF1 homolog 98795.5 18093112
509 NKG2-A/NKG2-B type II integral membrane protein isoform
NKG2-B 24222.6 7262384
510 F-box/WD repeat-containing protein 7 isoform 1 79662.5 16117781
511 leucine-rich repeats and immunoglobulin-like domains protein 3
isoform 1 precursor 117437.1 209862903
512 biliverdin reductase A precursor 33428.3 33589854
513 tubulin beta-3 chain isoform 1 50432.4 50592996
514 cytochrome P450 2F1 precursor 55501.0 19743565
515 transformation/transcription domain-associated protein isoform 1 437598.6 347360922
516 SH3 domain and tetratricopeptide repeats-containing protein 1 146944.2 145386551
Page 34
517 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1
protein 186202.7 34452732
518 lysophosphatidylcholine acyltransferase 2 60207.5 47086907
519 coiled-coil domain-containing protein 110 isoform a 96724.8 22749515
520 A-kinase anchor protein 9 isoform 3 452107.5 22538393
521 extended synaptotagmin-2 98901.0 45387945
522 SH3 domain-containing kinase-binding protein 1 isoform a 73125.9 13994242
523 coiled-coil domain-containing protein 34 isoform 2 26255.8 18087817
524 dynein heavy chain 7, axonemal 461158.7 151301127
525 myosin-10 228996.6 41406064
526 arginyl-tRNA synthetase, cytoplasmic 75378.5 15149476
527 proteoglycan 4 isoform A precursor 151075.6 67190163
528 nucleotide-binding oligomerization domain-containing protein 1 107690.5 5174617
529 lanC-like protein 2 50854.1 8923911
530 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 3 292276.7 145309309
531 whirlin isoform 1 96557.1 290746376
532 centrosome-associated protein 350 350927.9 171184451
533 complexin-4 18336.4 31795561
534 HAUS augmin-like complex subunit 5 71682.1 149944680
535 outer dense fiber protein 2-like isoform a 71961.8 296179395
536 myosin light chain kinase, smooth muscle isoform 2 203053.5 116008188
537 sterile alpha motif domain-containing protein 9 184278.9 38201706
538 uncharacterized protein C3orf19 53957.2 108773808
539 protein furry homolog 338871.6 117606355
540 alpha-mannosidase 2C1 115834.5 46852164
541 methionine synthase 140526.2 169790923
542 ankyrin-3 isoform 2 111097.9 32967599
543 tubulin polyglutamylase TTLL5 143576.5 50658079
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544 autism susceptibility gene 2 protein isoform 1 138981.3 17864090
545 zinc finger protein 34 64038.1 157954634
546 ras-related protein Rab-8B 23584.0 7706563
547 transducin beta-like protein 2 precursor 49797.6 7549793
548 zinc finger CCHC domain-containing protein 4 59009.6 148886718
549 spectrin beta chain, erythrocyte isoform a 267823.1 67782321
550 janus kinase and microtubule-interacting protein 2 94933.3 45237195
551 thyroid adenoma-associated protein 219604.8 38348727
552 midasin 632819.0 24415404
553 pentatricopeptide repeat-containing protein 3, mitochondrial
precursor 78549.2 38683855
554 toll-like receptor 1 precursor 90290.8 41350337
555 myosin light chain 5 19533.9 4505305
Table S4. Identification of proteins associated with LDs of human liver sample 3.
Reference MW Accession
Scan(s) Sp RSp
1 17-beta-hydroxysteroid dehydrogenase 13 isoform B 29604.7 210032112
2 fatty acid synthase 273423.2 41872631
3 ras GTPase-activating-like protein IQGAP2 180577.0 116089337
4 spectrin beta chain, brain 1 isoform 1 274606.5 112382250
5 very long-chain specific acyl-CoA dehydrogenase, mitochondrial
isoform 2 precursor 68058.1 76496475
6 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform c 116037.4 170295797
7 serum albumin preproprotein 69366.4 4502027
8 epoxide hydrolase 1 precursor 52948.5 209862837
9 alcohol dehydrogenase 4 40221.5 71565152
10 estradiol 17-beta-dehydrogenase 11 32935.6 142976729
11 perilipin-2 48075.1 34577059
12 clathrin heavy chain 1 191612.6 4758012
13 spectrin alpha chain, brain isoform 1 285091.3 194595509
14 methyltransferase-like protein 7A precursor 28318.9 89145417
Page 36
15 myosin-9 226529.8 12667788
16 ATP synthase subunit beta, mitochondrial precursor 56559.5 32189394
17 keratin, type I cytoskeletal 18 48057.5 4557888
18 keratin, type II cytoskeletal 1 66038.3 119395750
19 long-chain-fatty-acid--CoA ligase 1 77942.9 40807491
20 probable saccharopine dehydrogenase 47151.1 55770836
21 keratin, type I cytoskeletal 10 58800.6 195972866
22 dehydrogenase/reductase SDR family member 1 33908.8 209862901
23 protein diaphanous homolog 1 isoform 1 141346.4 119395758
24 peroxisomal multifunctional enzyme type 2 isoform 1 83024.9 313482810
25 tubulin beta-2A chain 49906.7 4507729
26 fructose-bisphosphate aldolase B 39472.8 40354205
27 ATP synthase subunit alpha, mitochondrial precursor 59750.3 4757810
28 trifunctional enzyme subunit alpha, mitochondrial precursor 82999.1 20127408
29 formimidoyltransferase-cyclodeaminase 58926.2 11140815
30 bile acyl-CoA synthetase precursor 75384.7 13325057
31 complement C3 precursor 187146.3 115298678
32 glycogen debranching enzyme isoform 1 174762.1 116734847
33 alpha-actinin-4 104853.3 12025678
34 lanosterol synthase isoform 2 82198.1 224177556
35 long-chain-fatty-acid--CoA ligase 5 isoform a 82262.5 42794756
36 tubulin alpha-1A chain 50135.3 17986283
37 17-beta-hydroxysteroid dehydrogenase 13 isoform A 33655.2 210032110
38 cullin-associated NEDD8-dissociated protein 1 136374.7 21361794
39 calnexin precursor 67567.8 10716563
40 annexin A6 isoform 1 75872.8 71773329
41 prelamin-A/C isoform 1 precursor 74139.0 27436946
42 UTP--glucose-1-phosphate uridylyltransferase isoform a 56939.9 48255966
43 fatty aldehyde dehydrogenase isoform 1 57669.1 73466520
44 cytochrome P450 2C9 precursor 55627.6 13699818
45 dimethylaniline monooxygenase [N-oxide-forming] 3 60033.2 50541961
46 bile salt sulfotransferase 33779.6 29540545
47 monoglyceride lipase isoform 1 34292.3 6005786
48 perilipin-1 55990.0 223718203
49 elongation factor 2 95337.6 4503483
50 talin-1 269764.4 223029410
51 78 kDa glucose-regulated protein precursor 72332.5 16507237
Page 37
52 C-1-tetrahydrofolate synthase, cytoplasmic 101530.5 222136639
53 endoplasmin precursor 92468.2 4507677
54 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase
(cyclizing) 58946.8 20149621
55 keratin, type II cytoskeletal 8 53703.9 4504919
56 betaine--homocysteine S-methyltransferase 1 44998.2 157266337
57 peroxisomal bifunctional enzyme isoform 2 69153.5 261878539
58 NADH-cytochrome b5 reductase 3 isoform 2 31628.5 193794826
59 neutral alpha-glucosidase AB isoform 3 precursor 109437.2 88900491
60 protein disulfide-isomerase precursor 57115.9 20070125
61 programmed cell death 6-interacting protein isoform 1 96022.6 22027538
62 perilipin-4 134430.4 122937195
63 PREDICTED: liver carboxylesterase 1-like 27540.5 341916335
64 plectin isoform 1e 513705.9 41322908
65 protein ERGIC-53 precursor 57548.6 5031873
66 NADPH--cytochrome P450 reductase 77047.7 127139033
67 perilipin-3 isoform 1 47074.7 255958282
68 alcohol dehydrogenase 1B 39835.3 34577061
69 aldehyde oxidase 147916.9 71773480
70 apolipoprotein B-100 precursor 515528.6 105990532
71 protein-glutamine gamma-glutamyltransferase 2 isoform a 77328.4 39777597
72 carnitine O-palmitoyltransferase 2, mitochondrial precursor 73776.6 4503023
73 sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 41900.0 8393516
74 ribosome-binding protein 1 108654.8 110611220
75 long-chain-fatty-acid--CoA ligase 3 80419.6 42794752
76 protein transport protein Sec23A 86160.3 38202214
77 retinol dehydrogenase 10 38087.3 25282469
78 general vesicular transport factor p115 107906.7 4505541
79 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform a
precursor 165648.8 169790915
80 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit
2 isoform 1 precursor 69283.5 35493916
81 keratin, type I cytoskeletal 9 62063.9 55956899
82 liver carboxylesterase 1 isoform c precursor 62392.5 68508957
83 D-3-phosphoglycerate dehydrogenase 56650.2 23308577
84 hypoxia up-regulated protein 1 precursor 111334.8 5453832
Page 38
85 cytosolic 10-formyltetrahydrofolate dehydrogenase 98828.6 21614513
86 prohibitin-2 isoform 1 33296.1 221307584
87 microsomal triglyceride transfer protein large subunit precursor 99350.6 153285408
88 alcohol dehydrogenase 1C 39867.4 4501933
89 coatomer subunit beta 107141.5 7705369
90 arylacetamide deacetylase 45733.4 68299767
91 succinate dehydrogenase [ubiquinone] flavoprotein subunit,
mitochondrial 72691.1 156416003
92 amine oxidase [flavin-containing] A 59681.3 4557735
93 enoyl-CoA hydratase, mitochondrial precursor 31387.2 194097323
94 actin, cytoplasmic 1 41736.5 4501885
95 alcohol dehydrogenase [NADP+] 36572.8 24497577
96 sorbitol dehydrogenase 38324.3 156627571
97 phenylalanine-4-hydroxylase 51861.8 4557819
98 aldehyde dehydrogenase family 8 member A1 isoform 3 48035.6 301500698
99 dimethylaniline monooxygenase [N-oxide-forming] 5 isoform 1 60220.2 221316672
100 tripeptidyl-peptidase 1 preproprotein 61247.6 5729770
101 dehydrogenase/reductase SDR family member on chromosome X
precursor 36442.9 193804850
102 hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1
precursor 56635.1 5031751
103 AP-2 complex subunit beta isoform b 104551.9 4557469
104 hemoglobin subunit alpha 15257.4 4504345
105 cytochrome P450 2C8 isoform b 47785.8 311893309
106 elongation factor 1-alpha 2 50469.8 4503475
107 acetyl-CoA acetyltransferase, mitochondrial precursor 45199.3 4557237
108 voltage-dependent anion-selective channel protein 1 30772.3 4507879
109 arginase-1 isoform 2 34734.7 10947139
110 T-complex protein 1 subunit zeta isoform a 58023.9 4502643
111 calcium-binding mitochondrial carrier protein Aralar2 isoform 2 74175.1 7657581
112 aldo-keto reductase family 1 member C1 36788.1 5453543
113 cytochrome P450 4A11 59347.5 158937242
114 argininosuccinate lyase isoform 1 51657.7 68303542
115 nicotinamide phosphoribosyltransferase precursor 55520.8 5031977
116 L-serine dehydratase/L-threonine deaminase 34625.1 33469958
117 heterogeneous nuclear ribonucleoprotein K isoform a 51027.9 14165437
Page 39
118 UDP-glucuronosyltransferase 2B7 precursor 60720.3 190194389
119 alpha-mannosidase 2 131139.6 51477714
120 junction plakoglobin 81744.3 12056468
121 glutamate dehydrogenase 2, mitochondrial precursor 61433.6 31377775
122 5'-AMP-activated protein kinase subunit gamma-1 isoform 1 37579.1 4506061
123 protein transport protein Sec24A isoform 1 119748.6 116174780
124 non-specific lipid-transfer protein isoform 1 proprotein 58993.3 19923233
125 catenin beta-1 85496.2 4503131
126 UDP-glucuronosyltransferase 1-1 precursor 59591.1 8850236
127 glutamate dehydrogenase 1, mitochondrial precursor 61397.5 4885281
128 carbonyl reductase [NADPH] 1 30374.7 4502599
129 fructose-1,6-bisphosphatase 1 36842.3 189083692
130 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 39095.4 31542303
131 very long-chain acyl-CoA synthetase isoform 1 70311.8 227499619
132 short-chain dehydrogenase/reductase 3 33548.2 31543615
133 plastin-2 70288.0 167614506
134 malate dehydrogenase, cytoplasmic isoform 2 36425.9 5174539
135 alpha-1-antitrypsin precursor 46736.2 50363217
136 reticulon-4 isoform A 129930.3 24431935
137 argininosuccinate synthase 46530.1 16950633
138 heat shock protein HSP 90-alpha isoform 1 98160.4 153792590
139 guanine nucleotide-binding protein subunit beta-2-like 1 35076.5 5174447
140 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 37330.8 20357529
141 exportin-2 110415.8 29029559
142 filamin-B isoform 2 278160.3 105990514
143 alpha-soluble NSF attachment protein 33232.5 47933379
144 amine oxidase [flavin-containing] B 58762.6 38202207
145 villin-1 92694.4 194394237
146 corticosteroid 11-beta-dehydrogenase isozyme 1 32400.8 5031765
147 ubiquitin-like modifier-activating enzyme 1 117848.1 23510340
148 cytochrome b-c1 complex subunit 2, mitochondrial precursor 48442.7 50592988
149 transitional endoplasmic reticulum ATPase 89321.3 6005942
150 ancient ubiquitous protein 1 45786.6 31712030
151 vimentin 53651.3 62414289
Page 40
152 phosphoglucomutase-1 isoform 1 61448.7 21361621
153 radixin 68563.4 4506467
154 long-chain-fatty-acid--CoA ligase 4 isoform 2 79187.6 12669909
155 regulator of G-protein signaling 14 61446.6 21361304
156 nesprin-1 isoform 1 1011101.0 330688408
157 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform 1
precursor 70729.6 66346721
158 RIB43A-like with coiled-coils protein 1 isoform 1 44014.7 72534784
159 keratin, type II cytoskeletal 2 epidermal 65432.4 47132620
160 calpain-1 catalytic subunit 81889.4 12408656
161 tubulin beta-2C chain 49830.7 5174735
162 rab GDP dissociation inhibitor alpha 50582.4 4503971
163 protein disulfide-isomerase A3 precursor 56782.0 21361657
164 glyceraldehyde-3-phosphate dehydrogenase 36053.0 7669492
165 short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
precursor 47485.1 4501859
166 fibrinogen gamma chain isoform gamma-A precursor 49496.2 70906437
167 UBX domain-containing protein 4 56777.2 24307965
168 retinal dehydrogenase 1 54861.5 21361176
169 membrane primary amine oxidase 84621.4 4502119
170 inter-alpha-trypsin inhibitor heavy chain H1 isoform a 101388.4 156119625
171 catenin alpha-1 100070.6 55770844
172 exportin-1 123385.0 4507943
173 2,4-dienoyl-CoA reductase, mitochondrial precursor 36067.5 4503301
174 apoptosis-inducing factor 2 40526.4 14318424
175 annexin A2 isoform 2 38603.8 209862831
176 GDH/6PGL endoplasmic bifunctional protein precursor 88892.2 52145310
177 hemoglobin subunit delta 16055.4 4504351
178 cystathionine beta-synthase 60586.2 4557415
179 rRNA 2'-O-methyltransferase fibrillarin 33784.0 12056465
180 erythrocyte band 7 integral membrane protein isoform a 31730.6 38016911
181 myosin-10 228996.6 41406064
182 serum paraoxonase/arylesterase 1 precursor 39731.0 19923106
183 keratin, type I cytoskeletal 16 51267.5 24430192
184 microsomal glutathione S-transferase 1 17598.6 9945306
185
dihydrolipoyllysine-residue succinyltransferase component of 2-
oxoglutarate dehydrogenase complex, mitochondrial isoform 1
precursor
48755.0 19923748
186 coatomer subunit gamma-2 97621.8 109134349
Page 41
187 large proline-rich protein BAG6 isoform a 119408.2 149158692
188 thymidine phosphorylase precursor 49955.2 166158922
189 cytochrome P450 4F8 precursor 59994.3 6005737
190 gamma-glutamyltransferase 5 isoform b 62260.8 153266885
191 SEC14-like protein 3 46047.9 27923592
192 3-ketoacyl-CoA thiolase, peroxisomal isoform a 44291.8 4501853
193 prohibitin 29803.9 4505773
194 tubulin alpha-1B chain 50151.3 57013276
195 cytochrome P450 2D6 isoform 1 55730.1 40805836
196 UDP-glucose 6-dehydrogenase isoform 1 55023.8 4507813
197 leukotriene-B(4) omega-hydroxylase 1 precursor 59853.2 13435391
198 estradiol 17-beta-dehydrogenase 2 42784.9 4504503
199 SEC14-like protein 2 isoform 1 46145.0 7110715
200 estradiol 17-beta-dehydrogenase 12 34323.9 7705855
201 gap junction beta-1 protein 32024.3 4504005
202 ras-related protein Rab-14 23896.8 19923483
203 PRA1 family protein 3 21614.6 5453704
204 B-cell receptor-associated protein 31 isoform b 27991.4 213511012
205 RNA-binding protein EWS isoform 2 68477.8 4885225
206 bile acid-CoA:amino acid N-acyltransferase 46298.9 4502351
207 ras-related protein Rap-1b isoform 2 16033.3 354459350
208 aldehyde dehydrogenase, mitochondrial isoform 1 precursor 56380.9 25777732
209 serine/threonine-protein kinase PAK 2 58042.3 32483399
210 acetolactate synthase-like protein 67867.3 21361361
211 glucose-6-phosphate isomerase isoform 2 63146.7 18201905
212 proteasome activator complex subunit 1 isoform 1 28722.9 5453990
213 L-lactate dehydrogenase A chain isoform 1 36688.5 5031857
214 ubiquitin-60S ribosomal protein L40 precursor 14728.2 77539055
215 histone H2A type 1-D 14107.4 10800130
216 myeloperoxidase precursor 83868.1 4557759
217 annexin A5 35936.5 4502107
218 short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor 44297.0 4557233
219 epoxide hydrolase 2 62615.4 27597073
220 OCIA domain-containing protein 1 isoform 1 27626.0 8923427
221 UDP-glucuronosyltransferase 1-7 precursor 59818.5 41282213
222 ATP-dependent RNA helicase DDX3X isoform 2 73156.0 301171467
223 COP9 signalosome complex subunit 7a 30276.4 7705330
Page 42
224 protein odr-4 homolog isoform 1 51102.8 57527756
225 lanosterol synthase isoform 1 83308.3 47933395
226 cytochrome P450 2E1 precursor 56848.6 10834998
227 UDP-glucuronosyltransferase 2B15 precursor 61036.0 116517299
228 cytoplasmic aconitate hydratase 98398.2 8659555
229 3-mercaptopyruvate sulfurtransferase isoform 2 33178.2 61835204
230 alpha-enolase isoform 1 47168.7 4503571
231 ER lumen protein retaining receptor 2 isoform 1 24421.7 5803050
232 carbonic anhydrase 2 29245.8 4557395
233 cathepsin B preproprotein 37821.4 4503139
234 alcohol dehydrogenase 6 isoform 2 39072.4 4501939
235 aldo-keto reductase family 1 member C4 37094.6 325652083
236 chromosome-associated kinesin KIF4A 139880.1 116686122
237 60S ribosomal protein L27 15797.6 4506623
238 HLA class I histocompatibility antigen, Cw-1 alpha chain precursor 40648.3 52630342
239 importin subunit beta-1 97169.7 19923142
240 glutathione S-transferase kappa 1 isoform a 25496.7 7705704
241 scavenger receptor cysteine-rich type 1 protein M130 isoform a
precursor 125450.2 344179110
242 vacuolar protein sorting-associated protein 13C isoform 1B 403082.1 66348091
243 lamin-B1 isoform 1 66407.9 5031877
244 S-adenosylmethionine synthase isoform type-1 43647.7 4557737
245 macrosialin isoform A precursor 37407.9 91199548
246 band 3 anion transport protein 101791.6 4507021
247 fibrinogen beta chain isoform 1 preproprotein 55927.8 70906435
248 1,4-alpha-glucan-branching enzyme 80459.3 189458812
249 ATP synthase subunit d, mitochondrial isoform a 18491.1 5453559
250 obg-like ATPase 1 isoform 1 44743.2 58761500
251 selenium-binding protein 1 52390.7 16306550
252 vigilin isoform b 137969.8 345199283
253 ras-related protein Rab-10 22540.8 256222019
254 4-aminobutyrate aminotransferase, mitochondrial precursor 56438.6 38679946
255 receptor expression-enhancing protein 6 20733.0 19923919
256 peroxisomal bifunctional enzyme isoform 1 79494.4 68989263
257 alanine aminotransferase 1 54636.6 4885351
258 eukaryotic translation initiation factor 3 subunit A 166568.5 4503509
259 peroxisomal trans-2-enoyl-CoA reductase 32544.1 19923817
Page 43
260 heat shock protein HSP 90-beta 83263.6 20149594
261 Golgi apparatus protein 1 isoform 2 precursor 135994.8 224586815
262 high mobility group protein B1 24893.6 4504425
263 lipopolysaccharide-binding protein precursor 53383.3 31652249
264 staphylococcal nuclease domain-containing protein 1 101996.3 77404397
265 annexin A1 38714.0 4502101
266 beta-2-glycoprotein 1 precursor 38298.0 153266841
267 heterogeneous nuclear ribonucleoprotein A3 39594.6 34740329
268 cytochrome P450 2A7 isoform 2 precursor 50666.4 15147328
269 coatomer subunit alpha isoform 2 138344.7 148536853
270 apolipoprotein E precursor 36153.8 4557325
271 myosin-Ic isoform c 117906.3 124494240
272 3 beta-hydroxysteroid dehydrogenase type 7 isoform b 21322.2 218563684
273 target of Myb protein 1 isoform 1 53818.1 4885637
274 eukaryotic translation initiation factor 3 subunit L isoform 1 66726.6 7705433
275 UDP-glucuronosyltransferase 1-4 precursor 60024.7 6005930
276 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit
1 precursor 68569.0 4506675
277 microsomal glutathione S-transferase 3 16516.2 4758714
278 beta,beta-carotene 9',10'-oxygenase isoform a 65673.7 82617624
279 surfeit locus protein 4 30393.8 19557691
280 synaptic vesicle membrane protein VAT-1 homolog 41920.0 18379349
281 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 40450.7 4504041
282 aminopeptidase N precursor 109538.8 157266300
283 aspartyl/asparaginyl beta-hydroxylase isoform f 83267.4 258613943
284 prenylcysteine oxidase 1 precursor 56639.8 166795301
285 ras-related protein Rab-7a 23489.6 34147513
286 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa
subunit precursor 50701.3 20070197
287 aflatoxin B1 aldehyde reductase member 3 37206.2 41152114
288 sodium-coupled neutral amino acid transporter 3 55772.8 5870893
289 signal transducer and activator of transcription 3 isoform 1 88067.3 21618340
290 plasminogen isoform 1 precursor 90568.6 4505881
291 catenin delta-1 isoform 2A 98048.4 332688222
Page 44
292 mitochondrial inner membrane protein isoform 1 83677.3 154354964
293 peroxiredoxin-4 precursor 30539.7 5453549
294 ATP-binding cassette sub-family D member 3 isoform a 75475.5 4506341
295 heterogeneous nuclear ribonucleoprotein U isoform a 90584.0 74136883
296 spectrin beta chain, brain 2 271291.8 5902122
297 serine--pyruvate aminotransferase 43009.7 4557289
298 proteasome inhibitor PI31 subunit 29816.5 145611426
299 rab GDP dissociation inhibitor beta isoform 1 50662.9 6598323
300 catalase 59755.8 4557014
301 oligosaccharyltransferase complex subunit OSTC 16829.2 24308271
302 patatin-like phospholipase domain-containing protein 3 52865.1 17196626
303 keratin, type II cytoskeletal 6A 60044.6 5031839
304 trifunctional enzyme subunit beta, mitochondrial precursor 51294.1 4504327
305 HCLS1-binding protein 3 42780.0 68800430
306 cytochrome P450 3A43 isoform 2 57669.5 16933533
307 39S ribosomal protein L28, mitochondrial precursor 30156.6 26051229
308 60S acidic ribosomal protein P0 34273.3 16933546
309 fibrinogen alpha chain isoform alpha-E preproprotein 94972.5 4503689
310 pyruvate carboxylase, mitochondrial precursor 129632.7 106049292
311 vacuolar protein sorting-associated protein VTA1 homolog 33879.0 21361741
312 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase 58068.1 166362724
313 heterogeneous nuclear ribonucleoprotein C-like 1 32142.2 61966711
314 cAMP-dependent protein kinase catalytic subunit alpha isoform 1 40589.3 4506055
315 C4b-binding protein alpha chain precursor 67032.9 4502503
316 mitochondrial glutamate carrier 1 34470.0 13375983
317 histamine N-methyltransferase isoform 1 33294.9 5901970
318 dynamin-2 isoform 5 97976.6 299758394
319 alpha-actinin-1 isoform b 103056.9 4501891
320 sulfotransferase 1A2 34310.4 4507303
321 vacuolar protein sorting-associated protein 35 91706.5 17999541
322 D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 38156.9 44680133
323 protein FAM5B precursor 89004.1 23943866
Page 45
324 vitamin K-dependent gamma-carboxylase isoform 1 87560.4 21361163
325 guanine nucleotide-binding protein G(i) subunit alpha-1 40360.8 33946324
326 ankyrin repeat and FYVE domain-containing protein 1 isoform 1 128485.4 110815813
327 apolipoprotein L3 isoform 1 44277.9 22035646
328 uridine 5'-monophosphate synthase 52221.3 4507835
329 POTE ankyrin domain family member F 121443.8 153791352
330 UDP-glucose:glycoprotein glucosyltransferase 1 precursor 177187.7 9910280
331 inverted formin-2 isoform 1 135623.5 149999380
332 gamma-glutamyl hydrolase precursor 35964.1 4503987
333 UDP-glucuronosyltransferase 2A2 60771.7 333609245
334 UDP-glucuronosyltransferase 1-9 precursor 59940.7 11276085
335 AP-3 complex subunit beta-1 121319.4 32484979
336 peroxiredoxin-6 25034.8 4758638
337 F-actin-capping protein subunit beta isoform 2 31350.3 330864679
338 protein NDRG2 isoform a 40797.9 42544211
339 hydroxyacid oxidase 1 40924.1 11068137
340 complement factor B preproprotein 85532.4 67782358
341 UDP-glucuronosyltransferase 2B28 isoform 2 precursor 38743.0 333033811
342 myosin-Ib isoform 2 124949.7 44889481
343 probable ATP-dependent RNA helicase DDX17 isoform 1 80272.0 38201710
344 mitochondrial import receptor subunit TOM40 homolog 37892.8 5174723
345 cadherin-4 isoform 2 96396.6 356640221
346 6-phosphofructokinase, liver type 85017.9 48762920
347 heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2 36005.7 4504447
348 alpha-2-macroglobulin precursor 163290.5 66932947
349 elongation factor Tu, mitochondrial precursor 49874.6 34147630
350 phosphatidylinositol-binding clathrin assembly protein isoform 1 70754.1 56788366
351 EH domain-containing protein 3 60886.7 7657056
352 alpha-1,3-mannosyl-glycoprotein 2-beta-N-
acetylglucosaminyltransferase 50878.0 167857778
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9,
mitochondrial precursor 42509.3 6681764
354 17-beta-hydroxysteroid dehydrogenase type 6 35965.5 19743808
355 cytochrome P450 2C19 precursor 55944.8 4503219
356 metal transporter CNNM2 isoform 3 60487.1 40068051
Page 46
357 splicing factor 3B subunit 1 isoform 1 145829.1 54112117
358 cytochrome P450 4F11 precursor 60145.5 193083178
359 ATP-binding cassette sub-family F member 1 isoform a 95925.1 69354671
360 E3 ubiquitin-protein ligase TTC3 229865.8 49640009
361 hemoglobin subunit epsilon 16202.7 4885393
362 RNA-binding protein 33 129985.5 151301053
363 apolipoprotein A-I preproprotein 30777.6 4557321
364 cytochrome b5 isoform 1 15330.0 41281768
365 rho GTPase-activating protein 35 170512.4 150417981
366 signal recognition particle 68 kDa protein 70729.2 24497620
367 prostaglandin reductase 1 isoform 2 32894.9 226056130
368 beta-glucuronidase precursor 74731.4 268834192
369 caprin-2 isoform 2 120973.4 23503235
370 PREDICTED: LOW QUALITY PROTEIN: arf-GAP with GTPase,
ANK repeat and PH domain-containing protein 10 75384.5 239744064
371 keratin, type II cytoskeletal 5 62378.0 119395754
372 phosphorylase b kinase regulatory subunit beta isoform a 124883.5 4505783
373 desmoplakin isoform I 331771.4 58530840
374 rho GTPase-activating protein 1 50435.4 4757766
375 acyl-coenzyme A synthetase ACSM5, mitochondrial precursor 64759.7 38505220
376 monoacylglycerol lipase ABHD12 isoform b 45558.0 24308097
377 ras-related protein Rab-2B isoform 2 19005.1 254281345
378 WD repeat-containing protein 7 isoform 1 163809.1 73747877
379 intraflagellar transport protein 172 homolog 197573.7 46358428
380 heat shock protein beta-1 22782.3 4504517
381 bactericidal permeability-increasing protein precursor 53899.4 157276599
382 prolargin precursor 43809.6 4506041
383 dual specificity mitogen-activated protein kinase kinase 1 43438.8 5579478
384 ADP/ATP translocase 1 33064.2 55749577
385 squalene monooxygenase 63922.8 62865635
386 60S ribosomal protein L30 12784.0 4506631
387 heat shock 70 kDa protein 1A/1B 70051.8 194248072
388 mitochondrial ribonuclease P protein 3 precursor 67315.0 62988276
389 melanoma inhibitory activity protein 3 precursor 213699.7 122891870
390 alpha-tocopherol transfer protein-like 38514.9 85861250
391 protein disulfide-isomerase A6 precursor 48121.0 5031973
392 sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform b 114756.1 24638454
393 acid ceramidase isoform b 46503.3 189011546
394 glutamyl aminopeptidase 109243.5 132814467
Page 47
395 elongation factor 1-gamma 50118.5 4503481
396 dual specificity testis-specific protein kinase 2 63639.2 110349799
397 protein PRRC1 46700.9 18677735
398 serotransferrin precursor 77049.5 4557871
399 60 kDa heat shock protein, mitochondrial 61054.2 31542947
400 calcium-binding mitochondrial carrier protein Aralar1 74761.4 21361103
401 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit
STT3A 80529.1 22749415
402 nuclear receptor ROR-beta 52072.3 19743907
403 WASH complex subunit strumpellin 134285.3 120952851
404 kelch-like protein 34 70611.6 23397572
405 histone H4 11367.3 4504301
406 cytochrome P450 2A13 56687.2 13699809
407 baculoviral IAP repeat-containing protein 3 68371.2 33946285
408 vesicle-associated membrane protein-associated protein A isoform 1 32613.3 94721250
409 rhophilin-1 73589.5 119120915
410 vitronectin precursor 54305.3 88853069
411 bifunctional UDP-N-acetylglucosamine 2-epimerase/N-
acetylmannosamine kinase isoform 1 83065.5 190014632
412 glutathione S-transferase A3 25301.5 24430144
413 protein transport protein Sec24B isoform a 137416.6 112382212
414 L-lactate dehydrogenase A-like 6B 41942.7 15082234
415 cytochrome P450 4A22 59245.5 62952506
416 zinc finger and BTB domain-containing protein 34 55533.8 149944640
417 myosin-14 isoform 3 232008.3 224831241
418 acyl-CoA dehydrogenase family member 9, mitochondrial precursor 68760.0 21361497
419 translational activator GCN1 292707.0 54607053
420 carbonyl reductase [NADPH] 3 30850.1 4502601
421 DNA-directed RNA polymerase III subunit RPC2 isoform 2 121119.4 238908505
422 fibroblast growth factor 10 precursor 23435.8 4758360
423 uncharacterized protein C9orf174 197342.3 302565871
424 protocadherin Fat 2 precursor 479314.7 13787217
425 T-complex protein 1 subunit alpha isoform a 60343.2 57863257
426 PREDICTED: complement C4-A isoform 1 192843.7 341916194
427 myosin-VI 148712.8 92859701
428 nitric oxide synthase, brain isoform 1 160968.7 10835173
429 thiosulfate sulfurtransferase 33428.7 17402865
430 striatin-3 isoform 2 77744.2 142976675
431 transient receptor potential cation channel subfamily M member 1
isoform 1 186543.7 354721145
Page 48
432 tumor necrosis factor receptor superfamily member 19 isoform 2
precursor 45305.2 23238204
433 TFIIH basal transcription factor complex helicase XPD subunit isoform
1 86908.7 15834617
434 protein QN1 homolog 161941.6 148612801
435 leukocyte immunoglobulin-like receptor subfamily B member 5 isoform
3 precursor 52968.7 125987593
436 prolactin receptor isoform 6 precursor 57952.2 324073295
437 myotilin isoform a 55394.8 5803106
438 ribosomal protein S6 kinase-like 1 60035.9 332801047
439 E3 ubiquitin-protein ligase TRIM22 isoform 1 56947.0 117938316
440 Golgi integral membrane protein 4 81879.8 7657138
441 E3 ubiquitin-protein ligase HERC2 527227.1 126032348
442 laminin subunit alpha-2 isoform a precursor 343931.7 28559088
443 progesterone-induced-blocking factor 1 89804.0 55769583
444 fibrous sheath-interacting protein 2 789892.5 297206791
445 kinesin-like protein KIF14 186489.8 7661878
446 zinc finger protein 655 isoform a 57406.7 28416427
447 cytochrome P450 3A5 isoform 1 57108.3 4503231
448 protein-L-isoaspartate O-methyltransferase domain-containing protein 1 40675.0 190360566
449 plasminogen activator inhibitor 1 isoform 1 precursor 45059.7 10835159
450 parathyroid hormone 2 receptor precursor 62235.5 4826954
451 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
isoform 124283.3 54792082
452 myotubularin-related protein 2 isoform 1 73380.8 44680154
453 FYVE, RhoGEF and PH domain-containing protein 5 159889.7 194018497
454 PREDICTED: macrophage mannose receptor 1-like 166044.1 341915493
455 serine/threonine-protein kinase 38 54189.9 6005814
456 uncharacterized protein KIAA2026 228084.7 148612838
457 leiomodin-2 61675.0 150378503
458 vacuolar protein sorting-associated protein 37D 27729.6 117938318
459 cytochrome P450 2J2 57610.3 18491008
460 scavenger mRNA-decapping enzyme DcpS 38608.5 7661734
461 serpin B4 44853.7 28076869
462 adenylosuccinate synthetase isozyme 2 50097.0 34577063
463 attractin isoform 1 preproprotein 158535.6 21450861
464 cullin-5 90954.7 40254446
465 keratin, type II cytoskeletal 4 56143.7 331999954
466 ATPase family AAA domain-containing protein 2 158552.9 24497618
Page 49
467 calmodulin-regulated spectrin-associated protein 2 166730.9 44955929
468 adenylate cyclase type 5 isoform 1 138906.6 34486092
469 spondin-1 precursor 90973.2 110347423
470 cytochrome P450 1A2 58407.1 73915100
471 stress-associated endoplasmic reticulum protein 2 7430.9 58219012
472 39S ribosomal protein L55, mitochondrial isoform a 15128.3 31563362
473 triple functional domain protein 346897.7 45439359
474 structural maintenance of chromosomes protein 2 135655.0 110347420
475 telomerase protein component 1 290486.4 21536371
476 protein PAT1 homolog 2 61463.6 223278366
477 small G protein signaling modulator 2 isoform 1 118306.7 148612795
478 zinc finger protein 556 51580.9 13376460
479 proteasome activator complex subunit 4 211331.6 163644283
480 integrator complex subunit 2 134345.5 24308211
481 peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform
1 74389.7 21314690
482 zinc finger protein 488 36961.8 23308499
483 FERM, RhoGEF and pleckstrin domain-containing protein 2 119887.7 7662310
484 creatine kinase B-type 42644.0 21536286
485 zinc finger protein 622 54271.8 15529978
486 80 kDa MCM3-associated protein 218402.0 19923191
487 PWWP domain-containing protein MUM1L1 79039.5 289577100
488 kinesin-like protein KIF24 151902.2 154426306
489 activating signal cointegrator 1 complex subunit 2 isoform 1 86359.9 20270253
490 receptor tyrosine-protein kinase erbB-2 isoform a precursor 137909.8 54792096
491 ubiquitin carboxyl-terminal hydrolase isozyme L1 24824.2 21361091
492 DNA-binding protein SATB1 isoform 1 85956.6 4506791
493 lactoylglutathione lyase 20777.6 118402586
494 protein FAM135A isoform c 169838.1 242117946
495 cystin-1 16393.0 81158080
496 centromere protein F 357524.8 55770834
497 U5 small nuclear ribonucleoprotein 200 kDa helicase 244504.7 40217847
498 putative uncharacterized protein C16orf96 125040.6 222446620
499 spectrin beta chain, erythrocyte isoform a 267823.1 67782321
500 glycerol kinase 2 60593.5 41393575
501 5-azacytidine-induced protein 1 isoform a 121846.8 111955084
Page 50
Table S5. Combined list of of proteins associated with LDs found in 3 human livers.
Reference MW Accession
Peptid
e (Hits)
Scan(s),
File Peptide
Sp RSp Ions
1 apolipoprotein B-100 precursor 515528.6
10599053
2
24 (21
3 0 0 0)
4118, 2-2 R.IGQDGISTSATTNLK.C 704.1 1 19/28
4608, 2-2 R.SEILAHWSPAK.L 2114.9 1 18/20
4980, 2-2 K.SGSSTASWIQNVDTK.Y 1145.6 1 16/28
4980, 2-2 K.HIYAISSAALSASYK.A 877.1 2 17/28
5142, 1-2 K.SGSSTASWIQNVDTK.Y 895.9 2 16/28
5470, 1-2 R.DLKVEDIPLAR.I 1555.5 1 16/20
5543, 2-2 R.EYSGTIASEANTYLNSK.S 1038.1 1 19/32
5684, 2-2 K.IAELSATAQEIIK.S 1570.3 1 18/24
5816, 2-2 K.ALYWVNGQVPDGVSK.V 553.0 1 14/28
6062, 2-2 K.ALVEQGFTVPEIK.T 714.3 1 17/24
6251, 2-2 R.LPYTIITTPPLK.D 1162.2 1 17/22
6280, 2-2 R.TEHGSEMLFFGNAIEGK.S 684.2 1 17/32
6436, 2-2 R.VIGNMGQTMEQLTPELK.S 751.0 1 17/32
6495, 2-2 K.IDDIWNLEVK.E 880.0 1 15/18
6612, 1-2 R.TGISPLALIK.G 806.6 1 16/18
6780, 2-2 R.LAAYLMLMR.S 1231.3 1 14/16
6891, 2-2 R.VLLDQLGTTISFER.I 688.5 2 16/26
7120, 2-2 K.NLTDFAEQYSIQDWAK.R 907.7 1 17/30
7125, 2-2 K.NLTDFAEQYSIQDWAK.R 2353.8 1 23/30
7190, 1-2 K.DKDQEVLLQTFLDDASPGDKR.L 1272.9 1 31/80
7690, 2-2 R.NIQEYLSILTDPDGK.G 925.0 1 17/28
8259, 1 R.ILGEELGFASLHDLQLLGK.L 1690.2 1 23/36
8775, 1 R.VPSYTLILPSLELPVLHVPR.N 1101.3 1 30/76
8944, 2-2 K.IAIANIIDEIIEK.L 857.5 1 16/24
2 clathrin heavy chain 1 191612.6 4758012
34 (34
0 0 0 0)
4258, 1-2 K.VIQCFAETGQVQK.I 2175.5 1 19/24
4452, 2-2 R.HSSLAGCQIINYR.T 1335.9 1 18/24
4454, 2-2 R.HSSLAGCQIINYR.T 658.0 1 15/24
4570, 1-2 R.HSSLAGCQIINYR.T 1442.7 1 18/24
4767, 2-2 K.VANVELYYR.A 1047.2 1 14/16
4928, 1-2 K.VSQPIEGHAASFAQFK.M 1385.0 1 20/30
4964, 2-2 R.KFNALFAQGNYSEAAK.V 1728.8 1 23/30
5110, 1-2 R.KFNALFAQGNYSEAAK.V 1616.6 1 22/30
5177, 1-2 K.IVLDNSVFSEHR.N 674.1 1 14/22
5388, 1-2 R.ALEHFTDLYDIKR.A 1107.6 1 17/24
5469, 1 K.LLYNNVSNFGR.L 1020.4 1 15/20
5616, 1-2 K.LHIIEVGTPPTGNQPFPK.K 563.6 1 20/34
5628, 1-2 K.LHIIEVGTPPTGNQPFPK.K 601.7 1 19/34
5834, 2-2 R.NNLAGAEELFAR.K 1396.4 1 18/22
5979, 1-2 R.NNLAGAEELFAR.K 1272.9 1 18/22
6070, 1 R.NNLAGAEELFAR.K 1097.8 1 15/22
6087, 1-2 R.GQFSTDELVAEVEKR.N 1086.9 1 20/28
Page 51
6290, 1-2 R.TSIDAYDNFDNISLAQR.L 2157.2 1 23/32
6834, 2-2 K.WLLLTGISAQQNR.V 1618.0 1 18/24
6857, 2-2 R.GQCDLELINVCNENSLFK.S 1246.5 1 23/34
7042, 1-2 K.WLLLTGISAQQNR.V 1735.6 1 19/24
7079, 1-2 R.GQCDLELINVCNENSLFK.S 859.3 1 20/34
7235, 2-2 K.SVNESLNNLFITEEDYQALR.T 653.9 1 19/38
7481, 1-2 K.SVNESLNNLFITEEDYQALR.T 1308.9 1 23/38
7586, 1 K.SVDPTLALSVYLR.A 2152.4 1 20/24
7613, 1 K.SVNESLNNLFITEEDYQALR.T 1118.0 1 22/38
7731, 2-2 R.NLQNLLILTAIK.A 1702.5 1 18/22
7924, 1-2 K.KVGYTPDWIFLLR.N 1103.1 1 15/24
7996, 1-2 R.NLQNLLILTAIK.A 1651.9 1 18/22
8087, 1 R.NLQNLLILTAIK.A 837.7 1 17/22
8115, 1 R.RPLIDQVVQTALSETQDPEEVSVTVK.A
1191.0 1 34/100
8140, 1 R.LPVVIGGLLDVDCSEDVIK.N 1572.3 1 21/36
8698, 1-2 K.VGYTPDWIFLLR.N 512.9 1 15/22
8786, 1 K.VGYTPDWIFLLR.N 665.3 1 17/22
3 long-chain-fatty-acid--CoA ligase 1 77942.9 40807491
38 (38
0 0 0 0)
3767, 2-2 R.IFGQANTTLKR.W 986.0 1 16/20
3831, 1-2 R.IFGQANTTLKR.W 842.0 1 16/20
3959, 2-2 R.VVECVMLCHGAK.I 804.0 1 16/22
4028, 1-2 R.VVECVMLCHGAK.I 640.2 1 14/22
4095, 2-2 R.GIQVSNNGPCLGSR.K 1495.1 1 19/26
4260, 2-2 R.IFGQANTTLK.R 932.4 1 16/18
4413, 1-2 K.DSGLKPFEQVK.G 963.9 1 16/20
4877, 1-2 R.NIVSDCSAFVK.A 566.2 1 14/20
4893, 1-2 R.NIVSDCSAFVK.A 829.6 1 17/20
4995, 2-2 K.TAEALDKDGWLHTGDIGK.W 1918.1 1 21/34
5038, 2-2 K.RGFEGSFEELCR.N 937.7 1 15/22
5133, 1-2 K.TAEALDKDGWLHTGDIGK.W 2160.3 1 34/68
5262, 2-2 K.GPNVFQGYLKDPAK.T 909.4 1 17/26
5354, 1-2 K.GPNVFQGYLKDPAK.T 1330.3 1 21/26
5504, 2-2 R.KPDQPYEWLSYK.Q 1405.4 1 18/22
5523, 2-2 R.GFEGSFEELCR.N 1310.5 1 16/20
5613, 2-2 K.AELSLVFVDKPEK.A 1168.3 1 18/24
5657, 1-2 R.KPKPPAPEDLAVICFTSGTTGNPK.G
1354.8 1 32/92
5850, 1 K.AELSLVFVDKPEK.A 1026.5 1 17/24
5970, 1 K.IIVVM*DAYGSELVER.G 897.7 1 19/28
6063, 1 K.IGFFQGDIR.L 1126.7 1 14/16
6218, 2-2 K.QVAELSECIGSALIQK.G 877.1 1 27/60
6342, 2-2 R.SQIDDLYSTIKV.- 1368.1 1 17/22
6780, 1 K.IIVVMDAYGSELVER.G 548.5 1 17/28
7499, 2-2 K.GITLHPELFSIDNGLLTPTMK.A 640.5 1 17/40
7755, 1-2 K.GITLHPELFSIDNGLLTPTMK.A 999.1 1 24/40
7898, 2-2 R.LM*VTGAAPVSATVLTFLR.A 587.0 1 20/34
7905, 2-2 R.LM*VTGAAPVSATVLTFLR.A 1243.5 1 29/68
8169, 1-2 R.LM*VTGAAPVSATVLTFLR.A 749.0 1 21/34
8172, 1-2 R.LM*VTGAAPVSATVLTFLR.A 912.4 1 26/68
Page 52
8204, 2-2 R.LMVTGAAPVSATVLTFLR.A 707.9 1 23/34
8206, 2-2 R.LMVTGAAPVSATVLTFLR.A 1077.7 1 27/68
8211, 2-2 R.LMVTGAAPVSATVLTFLR.A 634.9 1 22/34
8291, 1 R.LM*VTGAAPVSATVLTFLR.A 951.2 1 24/34
8468, 1-2 R.LMVTGAAPVSATVLTFLR.A 998.4 1 26/34
8477, 1-2 R.LMVTGAAPVSATVLTFLR.A 1044.2 1 30/68
8576, 1 R.LMVTGAAPVSATVLTFLR.A 591.3 1 20/34
8583, 1 R.LMVTGAAPVSATVLTFLR.A 884.1 1 26/68
4 fatty acid synthase 273423.2 41872631
27 (27
0 0 0 0)
4343, 2-2 R.VTVAGGVHISGLHTESAPR.R 882.9 1 20/36
4632, 1 R.VTVAGGVHISGLHTESAPR.R 1086.3 1 28/72
4686, 1-2 K.EDGLAQQQTQLNLR.S 923.6 1 15/26
5024, 2-2 R.AALQEELQLCK.G 1447.8 1 15/20
5033, 2-2 R.LQVVDQPLPVR.G 930.0 1 14/20
5550, 1-2 R.FPQLDSTSFANSR.D 1923.2 1 20/24
5728, 1 K.TGGAYGEDLGADYNLSQVCDGK.V 1233.3 1 22/42
6488, 1 K.GVDLVLNSLAEEK.L 1449.0 1 18/24
6717, 2-2 K.AINCATSGVVGLVNCLR.R 1701.6 1 23/32
6728, 1 K.VVVQVLAEEPEAVLK.G 748.8 1 16/28
6748, 1-2 K.SFYGSTLFLCR.R 1330.8 1 15/20
6780, 1-2 R.LNSVQSSERPLFLVHPIEGSTTVFHSLASR.L
968.6 1 35/116
6818, 1 R.LNSVQSSERPLFLVHPIEGSTTVFHSLASR.L
1284.5 1 38/116
6854, 1 K.SFYGSTLFLCR.R 1482.9 1 17/20
7299, 1 R.IPGLLSPHPLLQLSYTATDR.H 2459.3 1 39/76
7689, 1 R.LHLSGIDANPNALFPPVEFPAPR.G 708.8 1 28/88
7712, 1 R.EGGFLLLHTLLR.G 713.7 1 13/22
7799, 2-2 R.DNLEFFLAGIGR.L 2101.9 1 19/22
8049, 1-2 R.DNLEFFLAGIGR.L 2659.6 1 19/22
8114, 2-2 K.LPEDPLLSGLLDSPALK.A 1568.6 1 23/32
8313, 1 R.EACPELDYFVVFSSVSCGR.G 731.2 1 17/36
8333, 1 R.EACPELDYFVVFSSVSCGR.G 967.2 1 19/36
8398, 1-2 K.LPEDPLLSGLLDSPALK.A 1263.9 1 22/32
9442, 2-2 R.DLVEAVAHILGIR.D 1063.8 1 16/24
9533, 1 R.TLLEGSGLESIISIIHSSLAEPR.V 581.1 1 17/44
9686, 1 R.DLVEAVAHILGIR.D 1387.0 1 19/24
9744, 1-2 R.DLVEAVAHILGIR.D 1454.1 1 18/24
5 ras GTPase-activating-like protein IQGAP2 180577.0
11608933
7
29 (29
0 0 0 0)
3755, 1-2 R.KSFLHEQEENVVK.I 1429.3 1 18/24
4283, 1-2 K.SFLHEQEENVVK.I 932.2 1 15/22
4511, 1-2 R.FQATSSGPILR.E 669.0 1 14/20
5034, 2-2 K.AWVNQLETQTGEASK.L 669.4 1 17/28
5193, 1-2 K.AWVNQLETQTGEASK.L 1600.2 1 20/28
5356, 1 K.AWVNQLETQTGEASK.L 838.5 1 17/28
5372, 1 K.SKVDQVQDIVTGNPTVIK.M 1332.1 1 21/34
5523, 1-2 K.VDQVQDIVTGNPTVIK.M 2271.6 1 24/30
5648, 1 K.VDQVQDIVTGNPTVIK.M 2151.8 1 24/30
5670, 2-2 R.ITLEDVISHSK.K 1916.5 1 17/20
Page 53
5793, 1 K.TLVGSENPPLTVIR.K 1045.3 1 20/26
5822, 1-2 R.ITLEDVISHSK.K 1532.7 1 16/20
6182, 1 K.LPYDVTTEQALTYPEVK.N 1606.9 1 23/32
6777, 2-2 K.AAFYEEQINYYDTYIK.T 1060.2 1 20/30
6875, 2-2 R.VVAVGYINEAIDEGNPLR.T 1555.6 1 20/34
6993, 1-2 K.AAFYEEQINYYDTYIK.T 793.7 1 16/30
7085, 1-2 K.GVLLDIDDLQTNQFK.N 1372.8 1 18/28
7092, 2-2 R.NPNAVLTLVDDNLAPEYQK.E 618.0 1 20/36
7322, 1-2 R.NPNAVLTLVDDNLAPEYQK.E 756.1 1 20/36
7366, 1 K.QWVTLVVDVNQCLEGKK.S 660.3 1 16/32
7462, 1 R.NPNAVLTLVDDNLAPEYQK.E 1370.6 1 25/36
7872, 2-2 R.ENIWSASEELLLR.F 1372.3 1 18/24
8128, 1-2 R.ENIWSASEELLLR.F 957.8 1 16/24
8247, 1 R.ENIWSASEELLLR.F 1503.2 1 19/24
8694, 1 K.VNVNLLIYLLNK.K 1824.5 1 18/22
8768, 1-2 K.EIEDIIEEVTVGYIR.E 921.3 1 20/28
8853, 1 K.EIEDIIEEVTVGYIR.E 2156.9 1 23/28
9086, 1 K.VLNSIISSLDLLPYGLR.Y 613.7 1 17/32
10059, 1 K.IGGILANELSVDEAALHAAVIAINEAVEK.G
973.3 1 35/112
6 spectrin beta chain, brain 1 isoform 1 274606.5
11238225
0
23 (23
0 0 0 0)
4368, 1-2 K.TALPAQSAATLPAR.T 707.5 1 16/26
4492, 2-2 K.KHEAIETDIAAYEER.V 1119.3 1 19/28
4666, 1 K.IVSSSDVGHDEYSTQSLVK.K 1668.7 1 25/36
5001, 1 R.KKEIEELQSQAQALSQEGK.S 2000.5 1 33/72
5192, 1-2 R.LILEVHQFSR.D 976.5 1 14/18
5194, 1-2 K.EIEELQSQAQALSQEGK.S 1027.6 1 19/32
5204, 2-2 R.SQNIVTDSSSLSAEAIR.Q 2618.6 1 24/32
5266, 2-2 R.LQALDTGWNELHK.M 1705.0 1 19/24
5339, 1 K.EIEELQSQAQALSQEGK.S 1563.2 1 23/32
5384, 1 R.FQIQDISVETEDNKEK.K 1651.0 1 22/30
5495, 1 R.SQNIVTDSSSLSAEAIR.Q 2004.5 1 25/32
6814, 2-2 R.EVDDLEQWIAER.E 1108.5 1 15/22
6868, 1-2 R.LTTLELLEVR.R 1022.2 1 15/18
6980, 1 R.LTTLELLEVR.R 1480.0 1 17/18
7047, 1 K.DALLSALSIQNYHLECNETK.S 963.4 1 17/38
7094, 2-2 R.LVSQDNFGFDLPAVEAATK.K 566.6 1 18/36
7433, 1-2 K.FANSLVGVQQQLQAFNTYR.T 1458.2 1 21/36
7468, 1-2 R.DLDDFQSWLSR.T 1587.4 1 17/20
7558, 2-2 R.DASVAEAWLLGQEPYLSSR.E 597.0 1 15/36
7618, 1 R.DLDDFQSWLSR.T 1457.9 1 17/20
7799, 1-2 R.DASVAEAWLLGQEPYLSSR.E 1030.0 1 21/36
7955, 1-2 K.GNLEVLLFTIQSK.M 582.5 1 12/24
9569, 1 R.LWEYLLELLR.A 1699.7 1 16/18
7 myosin-9 226529.8 12667788
21 (20
1 0 0 0)
4571, 1-2 R.QAQQERDELADEIANSSGK.G 1057.7 1 27/72
4692, 2-2 R.IAEFTTNLTEEEEKSK.S 813.4 1 16/30
4719, 1-2 K.IAQLEEQLDNETKER.Q 1177.1 1 20/28
4809, 1-2 R.IAEFTTNLTEEEEKSK.S 1376.5 1 19/30
Page 54
4858, 1-2 K.VEAQLQELQVK.F 1071.2 1 14/20
5081, 1-2 K.KQELEEICHDLEAR.V 1795.8 1 19/26
5249, 2-2 K.ALELDSNLYR.I 1338.9 1 16/18
5480, 2-2 K.VIQYLAYVASSHK.S 2109.1 1 20/24
5520, 1-2 K.TDLLLEPYNK.Y 1172.7 1 15/18
5628, 1 K.HSQAVEELAEQLEQTKR.V 1104.8 1 28/64
6172, 1 K.EQADFAIEALAK.A 617.9 1 14/22
6423, 1-2 K.VSHLLGINVTDFTR.G 1591.7 1 20/26
7176, 1 K.LQVELDNVTGLLSQSDSK.S 1189.5 1 22/34
7194, 1 R.ELESQISELQEDLESER.A 1568.4 1 24/32
7479, 1-2 R.LQQELDDLLVDLDHQR.Q 1379.6 1 19/30
7601, 1 R.LQQELDDLLVDLDHQR.Q 1185.9 1 19/30
8030, 1-2 R.VISGVLQLGNIVFK.K 1793.5 1 20/26
8034, 1-2 K.DFSALESQLQDTQELLQEENR.Q 1023.6 1 20/40
8145, 1 R.VISGVLQLGNIVFK.K 2101.0 1 21/26
8178, 1 K.DFSALESQLQDTQELLQEENR.Q 1116.5 1 22/40
8940, 1 R.INFDVNGYIVGANIETYLLEK.S 657.3 1 18/40
8 plectin isoform 1e 513705.9 41322908
19 (18
1 0 0 0)
4401, 1-2 R.SSSVGSSSSYPISPAVSR.T 532.6 1 20/34
4536, 1-2 R.VPLDEALQR.G 524.0 1 14/16
4661, 1 K.AYSDPSTGEPATYGELQQR.C 841.1 1 22/36
5393, 1-2 K.GFFDPNTHENLTYR.Q 803.3 1 17/26
5556, 2-2 K.AKLEQLFQDEVAK.A 1369.1 1 17/24
5619, 1-2 R.LQEAGILSAEELQR.L 1813.1 1 21/26
5651, 1-2 R.LLDAQLSTGGIVDPSK.S 972.8 1 18/30
5981, 2-2 R.LTAEDLFEAR.I 1390.7 1 16/18
5988, 1-2 R.SLESLHSFVAAATK.E 842.2 1 16/26
6130, 1-2 R.LTAEDLFEAR.I 975.0 1 15/18
6292, 2-2 R.SLVPAAELLESR.V 786.1 1 18/22
6435, 2-2 K.VQSGSESVIQEYVDLR.T 850.1 1 16/30
6449, 1-2 R.SLVPAAELLESR.V 632.5 1 17/22
6642, 1 R.QTNLENLDQAFSVAER.D 671.9 2 16/30
6677, 1-2 R.APVPASELLASGVLSR.A 1422.7 1 22/30
7042, 1 K.LQNVQIALDYLR.H 1180.3 1 17/22
7290, 1-2 R.ESADPLGAWLQDAR.R 1039.4 1 18/26
7406, 2-2 R.GLFDEEMNEILTDPSDDTK.G 567.9 1 14/36
7468, 1 K.FLEGTSCIAGVFVDATK.E 859.3 1 19/32
9 alcohol dehydrogenase 4 40221.5 71565152
37 (37
0 0 0 0)
3873, 2-2 K.ALGATDCLNPR.D 1962.0 1 19/20
3939, 1-2 K.ALGATDCLNPR.D 1790.1 1 18/20
3972, 1-2 K.ALGATDCLNPR.D 1308.2 1 16/20
4644, 1-2 K.ISEAFDLM*NQGK.S 660.6 1 14/22
4947, 2-2 K.GGVDFALDCAGGSETM*K.A 2048.5 1 23/32
4986, 2-2 R.IIGIDINSEK.F 685.9 1 12/18
4998, 2-2 R.IIGIDINSEK.F 690.1 1 12/18
5109, 1-2 R.IIGIDINSEK.F 1011.5 1 13/18
5256, 1 K.GGVDFALDCAGGSETM*K.A 654.4 1 20/32
5482, 1-2 K.GGVDFALDCAGGSETMK.A 1680.7 1 23/32
5548, 2-2 R.IQIIATSLCHTDATVIDSK.F 3189.2 1 26/36
Page 55
5690, 1-2 R.IQIIATSLCHTDATVIDSK.F 2432.5 1 25/36
5970, 1-2 K.CKFCLSPLTNLCGK.I 634.5 1 14/26
6240, 2-2 R.VCLLGCGFSTGYGAAINNAK.V 3468.9 1 29/38
6257, 2-2 R.VCLLGCGFSTGYGAAINNAK.V 3328.6 1 29/38
6335, 2-2 K.AAIAWEAGKPLCIEEVEVAPPK.A 957.4 1 24/42
6350, 2-2 K.FCLSPLTNLCGK.I 781.2 1 17/22
6440, 1-2 R.VCLLGCGFSTGYGAAINNAK.V 3546.2 1 29/38
6501, 2-2 K.AALDCTTAGWGSCTFIGVAAGSK.G
1384.6 1 25/44
6524, 1 R.VCLLGCGFSTGYGAAINNAK.V 1664.6 1 34/76
6536, 1-2 K.AAIAWEAGKPLCIEEVEVAPPK.A 1290.4 1 28/42
6612, 1 K.AAIAWEAGKPLCIEEVEVAPPK.A 1146.5 1 26/42
6620, 1 K.FCLSPLTNLCGK.I 697.1 1 16/22
6648, 1 R.VCLLGCGFSTGYGAAINNAK.V 1708.7 1 26/38
6689, 1-2 K.AALDCTTAGWGSCTFIGVAAGSK.G
1169.6 1 23/44
7034, 2-2 R.DLHKPIQEVIIELTK.G 927.4 1 20/28
7041, 2-2 R.DLHKPIQEVIIELTK.G 1081.9 1 21/28
7167, 1-2 K.KFNLDALVTHTLPFDK.I 912.4 1 16/30
7198, 1 K.GKPVYHFFGTSTFSQYTVVSDINLAK.I
1137.9 1 33/100
7247, 1 K.KFNLDALVTHTLPFDK.I 977.0 1 17/30
7262, 1-2 R.DLHKPIQEVIIELTK.G 1055.7 1 21/28
7275, 1-2 R.DLHKPIQEVIIELTK.G 996.1 1 21/28
7335, 1 R.DLHKPIQEVIIELTK.G 571.2 1 16/28
7378, 1 R.DLHKPIQEVIIELTK.G 2105.3 1 32/56
7407, 1 R.DLHKPIQEVIIELTK.G 2061.1 1 31/56
7786, 1-2 K.FNLDALVTHTLPFDK.I 1582.6 1 21/28
9273, 1 K.FNLDALVTHTLPFDKISEAFDLMNQGK.S
1054.5 1 32/104
10 spectrin alpha chain, brain isoform 1 285091.3
19459550
9
22 (20
2 0 0 0)
3729, 1-2 K.LSDDNTIGKEEIQQR.L 949.4 1 19/28
4430, 1-2 K.LIQEQHPEEELIK.T 589.8 4 13/24
4871, 1-2 R.DLAALEDKVK.A 1519.6 1 15/18
5162, 1 K.ALCAEADRLQQSHPLSATQIQVK.R 1327.1 1 33/88
5663, 1-2 R.DLAALGDKVNSLGETAER.L 655.3 1 17/34
5852, 1 K.CTELNQAWSSLGK.R 748.7 1 16/24
6153, 1-2 R.EANELQQWINEK.E 967.5 1 13/22
6628, 2-2 R.SSLSSAQADFNQLAELDR.Q 1064.5 2 19/34
6843, 1-2 R.SSLSSAQADFNQLAELDR.Q 2109.0 1 24/34
6846, 1 R.KVEDLFLTFAK.K 1260.8 1 17/20
7172, 1-2 R.AQLADSFHLQQFFR.D 826.2 1 16/26
7252, 1-2 K.LDENSAFLQFNWK.A 711.0 1 14/24
7252, 2-2 R.LAALADQWQFLVQK.S 818.0 1 14/26
7470, 1-2 R.LAALADQWQFLVQK.S 1603.6 1 18/26
8030, 1 R.GLVSSDELAKDVTGAEALLER.H 608.3 1 15/40
8078, 2-2 K.IAALQAFADQLIAAGHYAK.G 1197.5 1 33/72
8162, 1 R.AGTFQAFEQFGQQLLAHGHYASPEIK.Q
612.5 1 27/100
8355, 1-2 K.IAALQAFADQLIAAGHYAK.G 1644.2 1 20/36
Page 56
8422, 1 K.IAALQAFADQLIAAGHYAK.G 1610.2 1 34/72
8438, 1 K.IAALQAFADQLIAAGHYAK.G 1683.1 1 21/36
9080, 1 K.ALINADELASDVAGAEALLDR.H 1575.7 1 30/80
9081, 1 K.ALINADELASDVAGAEALLDR.H 1591.2 1 22/40
11 epoxide hydrolase 1 precursor 52948.5
20986283
7
31 (31
0 0 0 0)
3909, 2-2 R.FYKENLGQGWM*TQKHER.M 1784.5 1 29/64
4596, 2-2 R.EDDSIRPFKVETSDEEIHDLHQR.I 670.0 1 34/88
4607, 1-2 R.FYKENLGQGWM*TQK.H 545.3 1 16/26
4760, 1-2 R.EDDSIRPFKVETSDEEIHDLHQR.I 1113.8 1 28/88
4900, 1 R.EDDSIRPFKVETSDEEIHDLHQR.I 1333.9 1 32/88
5714, 2-2 R.DVELLYPVK.E 994.2 1 12/16
5728, 2-2 R.DVELLYPVK.E 1015.4 1 12/16
5865, 1-2 R.DVELLYPVK.E 948.5 1 12/16
5879, 1-2 R.DVELLYPVK.E 1102.2 1 12/16
6212, 2-2 R.GGHFAAFEEPELLAQDIRK.F 1565.2 1 33/72
6264, 2-2 K.NHGLSDEHVFEVICPSIPGYGFSEASSKK.G
690.0 1 32/112
6447, 1-2 R.GGHFAAFEEPELLAQDIRK.F 2061.2 1 38/72
6476, 1 R.GGHFAAFEEPELLAQDIRK.F 2044.0 1 26/36
6554, 2-2 K.NHGLSDEHVFEVICPSIPGYGFSEASSK.K
934.1 1 37/108
6686, 2-2 R.DKEETLPLEDGWWGPGTR.S 733.5 1 22/34
6711, 2-2 R.GGHFAAFEEPELLAQDIR.K 1934.0 1 24/34
6729, 2-2 R.GGHFAAFEEPELLAQDIR.K 2449.3 1 27/34
6876, 1 K.NHGLSDEHVFEVICPSIPGYGFSEASSK.K
581.5 1 18/54
6940, 1-2 R.GGHFAAFEEPELLAQDIR.K 2144.6 1 25/34
6962, 1-2 R.GGHFAAFEEPELLAQDIR.K 2476.3 1 27/34
7013, 1 R.DKEETLPLEDGWWGPGTR.S 677.8 1 22/34
7539, 1-2 R.FLGLTERDVELLYPVK.E 533.2 1 16/30
7614, 2-2 K.PLLMVHGWPGSFYEFYK.I 1050.2 1 20/32
7665, 2-2 R.ESGYM*HIQCTKPDTVGSALNDSPVGLAAYILEK.F
823.6 1 33/128
7797, 2-2 R.ESGYMHIQCTKPDTVGSALNDSPVGLAAYILEK.F
835.7 1 31/128
7881, 1-2 K.PLLMVHGWPGSFYEFYK.I 930.0 1 19/32
7966, 1 K.PLLMVHGWPGSFYEFYK.I 807.7 1 18/32
8043, 1 R.ESGYM*HIQCTKPDTVGSALNDSPVGLAAYILEK.F
1183.2 1 38/128
8057, 1-2 R.ESGYMHIQCTKPDTVGSALNDSPVGLAAYILEK.F
969.1 1 35/128
8361, 1-2 K.VYVPTGFSAFPFELLHTPEK.W 527.6 1 19/38
8450, 1 K.VYVPTGFSAFPFELLHTPEK.W 550.0 1 19/38
12 17-beta-hydroxysteroid dehydrogenase 13 isoform B 29604.7
21003211
2
46 (46
0 0 0 0)
5127, 1-2 R.MQNIQFEAVVGHK.I 852.6 2 15/24
5282, 1 R.MQNIQFEAVVGHK.I 1232.8 1 17/24
5283, 1 R.MQNIQFEAVVGHK.I 1298.1 1 26/48
5534, 1-2 R.SLIDGILTNKK.M 786.6 1 14/20
5672, 2-2 R.KSVAGEIVLITGAGHGIGR.Q 1581.6 1 34/72
Page 57
5678, 2-2 R.KSVAGEIVLITGAGHGIGR.Q 2331.2 1 26/36
5775, 2-2 R.NHGHIVTVASVCGHEGIPYLIPYCSSK.F
744.4 1 30/104
5802, 1-2 R.KSVAGEIVLITGAGHGIGR.Q 1226.8 1 32/72
5810, 1-2 R.GLTSELQALGK.T 1353.9 1 17/20
5864, 1 R.KSVAGEIVLITGAGHGIGR.Q 1629.8 1 33/72
5872, 1 R.KSVAGEIVLITGAGHGIGR.Q 2672.0 1 28/36
5882, 1 R.GLTSELQALGK.T 1233.1 1 17/20
5930, 1-2 R.NHGHIVTVASVCGHEGIPYLIPYCSSK.F
731.3 1 30/104
5960, 1 R.NHGHIVTVASVCGHEGIPYLIPYCSSK.F
1182.2 1 35/104
6020, 2-2 K.TSCLCPVFVNTGFTK.N 763.7 1 20/28
6093, 2-2 R.NHGHIVTVASVCGHEGIPYLIPYCSSK.F
621.6 1 27/104
6161, 1-2 K.TSCLCPVFVNTGFTK.N 648.7 1 16/28
6566, 1-2 K.KEVGDVTIVVNNAGTVYPADLLSTKDEEITK.T
1723.4 1 42/120
6566, 2-2 K.SVAGEIVLITGAGHGIGR.Q 870.5 1 20/34
6680, 1-2 K.SVAGEIVLITGAGHGIGR.Q 1430.0 1 22/34
6681, 2-2 R.LWPVLETDEVVR.S 524.2 1 15/22
6722, 1 K.KEVGDVTIVVNNAGTVYPADLLSTKDEEITK.T
1745.4 1 40/120
6740, 2-2 R.LWPVLETDEVVR.S 656.6 1 17/22
6758, 1 K.SVAGEIVLITGAGHGIGR.Q 1477.0 1 23/34
6825, 1 K.SVAGEIVLITGAGHGIGR.Q 1544.6 1 24/34
6862, 1 K.KEVGDVTIVVNNAGTVYPADLLSTK.D
1635.5 1 24/48
6927, 1-2 K.SVAGEIVLITGAGHGIGR.Q 708.5 1 17/34
7035, 1 R.LWPVLETDEVVR.S 582.2 1 14/22
7041, 1 R.LWPVLETDEVVR.S 957.6 1 19/22
7086, 2-2 K.EVGDVTIVVNNAGTVYPADLLSTK.D
523.1 1 16/46
7232, 1 K.EVGDVTIVVNNAGTVYPADLLSTKDEEITK.T
1154.0 1 34/116
7326, 2-2 R.QSILVLWDINK.V 505.1 1 13/20
7335, 1-2 K.EVGDVTIVVNNAGTVYPADLLSTK.D
1197.2 1 25/46
7438, 1 K.EVGDVTIVVNNAGTVYPADLLSTK.D
1264.6 1 24/46
7455, 1 K.EVGDVTIVVNNAGTVYPADLLSTK.D
754.9 1 21/46
7703, 1 R.QSILVLWDINK.V 803.5 1 16/20
7985, 1-2 K.TFEVNILGHFWITK.A 1671.2 1 20/26
8076, 1 K.TFEVNILGHFWITK.A 1575.4 1 21/26
8121, 1 K.TFEVNILGHFWITK.A 1148.4 1 19/26
9753, 1 R.LWPVLETDEVVR.S 749.4 1 17/22
9984, 1 K.TFEVNILGHFWITK.A 1026.8 1 16/26
10324, 1 K.TFEVNILGHFWITK.A 649.3 1 16/26
10659, 1 K.TFEVNILGHFWITK.A 660.8 2 14/26
Page 58
11326, 1 K.TFEVNILGHFWITK.A 526.4 1 12/26
12052, 1 K.SVAGEIVLITGAGHGIGR.Q 731.3 1 16/34
12080, 1 K.TSCLCPVFVNTGFTK.N 656.5 1 18/28
13 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform c 116037.4
17029579
7
23 (23
0 0 0 0)
5406, 2-2 R.SAYALGGLGSGICPNR.E 1216.0 1 20/30
5408, 2-2 K.TVLM*NPNIASVQTNEVGLK.Q 1009.5 1 19/36
5675, 1-2 R.FLGVAEQLHNEGFK.L 1729.5 1 21/26
5694, 1 K.TVLM*NPNIASVQTNEVGLK.Q 836.3 1 18/36
5856, 2-2 K.VLGTSVESIMATEDR.Q 997.5 1 16/28
5876, 1 K.AFAMTNQILVEK.S 1551.6 1 18/22
5915, 1 K.AADTIGYPVMIR.S 525.3 1 14/22
6006, 1-2 K.VLGTSVESIMATEDR.Q 1572.3 1 20/28
6094, 1 K.VLGTSVESIMATEDR.Q 974.4 1 18/28
6144, 2-2 K.HLPTLDHPIIPADYVAIK.A 610.3 1 27/68
6368, 1 K.HLPTLDHPIIPADYVAIK.A 916.2 1 31/68
6387, 1 K.HLPTLDHPIIPADYVAIK.A 756.6 1 18/34
6459, 2-2 K.TLGVDFIDVATK.V 910.7 1 18/22
6651, 1-2 K.TLGVDFIDVATK.V 808.1 1 17/22
6747, 1 K.TLGVDFIDVATK.V 915.4 1 18/22
7049, 2-2 K.IALGIPLPEIK.N 526.3 1 16/20
7270, 1-2 K.IALGIPLPEIK.N 567.8 1 16/20
7440, 1-2 R.TAVDSGIPLLTNFQVTK.L 576.7 1 21/32
7524, 1 R.HLGIVGECNIQFALHPTSMEYCIIEVNAR.L
875.1 1 31/112
7550, 1 R.TAVDSGIPLLTNFQVTK.L 746.6 1 22/32
7960, 1-2 K.IAPSFAVESIEDALK.A 1345.0 1 22/28
8246, 1-2 K.AFAISGPFNVQFLVK.G 937.7 1 19/28
8721, 1 R.SIFSAVLDELK.V 934.3 1 15/20
14 ATP synthase subunit beta, mitochondrial precursor 56559.5 32189394
21 (21
0 0 0 0)
4662, 2-2 K.AHGGYSVFAGVGER.T 1832.6 1 23/26
4769, 1 R.IM*DPNIVGSEHYDVAR.G 638.8 1 18/30
5037, 1-2 K.VALVYGQMNEPPGAR.A 566.9 1 15/28
5346, 2-2 R.IMNVIGEPIDER.G 928.5 1 15/22
5500, 1-2 R.IMNVIGEPIDER.G 1209.7 1 17/22
5594, 2-2 R.LVLEVAQHLGESTVR.T 1730.9 1 21/28
5729, 1-2 R.LVLEVAQHLGESTVR.T 1105.2 1 17/28
5847, 1 R.LVLEVAQHLGESTVR.T 1487.3 1 20/28
6129, 1-2 K.VLDSGAPIKIPVGPETLGR.I 982.3 1 29/72
7220, 2-2 R.VALTGLTVAEYFR.D 1397.6 1 18/24
7233, 1 R.AIAELGIYPAVDPLDSTSR.I 543.9 1 19/36
7464, 1-2 R.VALTGLTVAEYFR.D 1636.8 1 19/24
7551, 1 K.KGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSR.A
1884.0 1 46/144
7616, 1 R.VALTGLTVAEYFR.D 1472.8 1 19/24
7712, 1-2 R.FLSQPFQVAEVFTGHMGK.L 682.2 1 29/68
7780, 1-2 K.TVLIM*ELINNVAK.A 1055.7 1 15/24
7958, 1 K.GSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSR.A
863.3 1 36/140
8481, 2-2 K.TVLIMELINNVAK.A 1697.3 1 18/24
Page 59
8774, 1-2 K.TVLIMELINNVAK.A 2176.9 1 19/24
8834, 1 K.TVLIMELINNVAK.A 2180.6 1 19/24
9166, 1 R.LVLEVAQHLGESTVR.T 947.6 1 16/28
15 peroxisomal multifunctional enzyme type 2 isoform 1 83024.9
31348281
0
21 (21
0 0 0 0)
4068, 1-2 R.RVLQQFADNDVSR.F 795.1 1 17/24
4302, 1-2 R.VLQQFADNDVSR.F 1341.0 1 18/22
4412, 1-2 R.ATSTATSGFAGAIGQK.L 2067.5 1 23/30
4433, 1-2 R.ATSTATSGFAGAIGQK.L 1681.0 1 21/30
4976, 1-2 K.GSLAADKVVEEIR.R 1281.3 1 16/24
5296, 2-2 R.ISDEDWDIIHR.V 1535.8 1 16/20
5558, 1 R.ISDEDWDIIHR.V 1445.8 1 16/20
5592, 1-2 K.VLHGEQYLELYKPLPR.A 1849.7 1 21/30
5645, 1-2 R.IDVVVNNAGILR.D 1041.6 1 16/22
5692, 1 K.VLHGEQYLELYKPLPR.A 1603.1 1 20/30
5751, 1 R.IDVVVNNAGILR.D 1336.2 1 17/22
5867, 2-2 R.IIMTSSASGIYGNFGQANYSAAK.L 612.9 1 19/44
6293, 2-2 K.VQETGDIVISNAYVDLAPTSGTSAK.T
1230.7 1 23/48
6368, 2-2 K.VAVAIPNRPPDAVLTDTTSLNQAALYR.L
1965.9 1 39/104
6478, 1-2 K.VQETGDIVISNAYVDLAPTSGTSAK.T
1120.8 1 24/48
6545, 1-2 K.VAVAIPNRPPDAVLTDTTSLNQAALYR.L
1029.2 1 32/104
6779, 1 K.LQSTFVFEEIGR.R 918.4 1 15/22
7658, 2-2 K.LGLLGLANSLAIEGR.K 1557.5 1 21/28
8013, 1 K.LGLLGLANSLAIEGR.K 879.5 1 17/28
8247, 1-2 K.FIYEGSSDFSCLPTFGVIIGQK.S 879.6 1 23/42
8367, 1 K.FIYEGSSDFSCLPTFGVIIGQK.S 814.0 1 20/42
16 tubulin beta-2A chain 49906.7 4507729
26 (20
6 0 0 0)
3852, 1-2 -.M*REIVHIQAGQCGNQIGAK.F 791.6 1 22/72
4022, 2-2 R.EIVHIQAGQCGNQIGAK.F 2424.0 1 25/32
4023, 2-2 R.EIVHIQAGQCGNQIGAK.F 2023.2 1 31/64
4104, 1-2 R.EIVHIQAGQCGNQIGAK.F 1975.4 1 30/64
4134, 1-2 R.EIVHIQAGQCGNQIGAK.F 1002.4 1 22/32
5676, 1-2 R.KLAVNMVPFPR.L 824.7 1 15/20
5866, 1-2 R.AILVDLEPGTM*DSVR.S 628.8 1 18/28
5974, 1 R.AILVDLEPGTM*DSVR.S 791.6 2 18/28
6110, 2-2 K.LAVNMVPFPR.L 869.2 1 17/18
6281, 1-2 K.LAVNMVPFPR.L 885.5 1 17/18
6309, 2-2 R.AILVDLEPGTMDSVR.S 710.3 1 19/28
6830, 2-2 K.NSSYFVEWIPNNVK.T 605.7 1 15/26
7036, 1-2 K.NSSYFVEWIPNNVK.T 569.2 1 15/26
7203, 2-2 K.GHYTEGAELVDSVLDVVRK.E 659.9 1 26/72
7262, 2-2 R.LHFFMPGFAPLTSR.G 654.7 1 16/26
7403, 2-2 K.NSSYFVEWIPNNVK.T 517.6 1 14/26
7450, 2-2 K.M*SATFIGNSTAIQELFK.R 770.3 1 17/32
7484, 1-2 R.LHFFMPGFAPLTSR.G 582.7 1 16/26
7534, 1 K.GHYTEGAELVDSVLDVVRK.E 1522.4 1 34/72
Page 60
7587, 1 R.LHFFMPGFAPLTSR.G 576.7 1 16/26
7613, 2-2 K.GHYTEGAELVDSVLDVVR.K 2982.8 1 26/34
7630, 1-2 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G
627.8 1 25/100
7792, 1 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G
704.2 1 20/50
8260, 1-2 K.LTTPTYGDLNHLVSATMSGVTTCLR.F
579.7 1 18/48
8270, 1-2 K.LTTPTYGDLNHLVSATMSGVTTCLR.F
1310.8 1 33/96
8355, 1 K.LTTPTYGDLNHLVSATMSGVTTCLR.F
883.4 1 28/96
17 bile acyl-CoA synthetase precursor 75384.7 13325057
18 (18
0 0 0 0)
4188, 2-2 R.YLCNIPQQPEDR.T 644.1 1 17/22
4275, 1-2 R.YLCNIPQQPEDR.T 534.1 1 16/22
4448, 2-2 R.GMPLAHSVLSSGAR.V 800.3 1 17/26
4956, 1-2 K.VGM*AAVQLAPGQTFDGEK.L 656.1 1 19/34
5492, 2-2 K.VGMAAVQLAPGQTFDGEK.L 726.5 1 20/34
5643, 1-2 K.VGMAAVQLAPGQTFDGEK.L 805.6 1 21/34
6429, 2-2 R.SPALFIYTSGTTGLPK.P 1294.9 1 17/30
6598, 2-2 R.CFYLSHTSPTPGVGALGAALDAAPSHPVPADLR.A
1616.6 1 39/128
6740, 1-2 R.SPALFIYTSGTTGLPKPAILTHER.V 559.4 1 27/92
6897, 1 R.CFYLSHTSPTPGVGALGAALDAAPSHPVPADLR.A
1943.7 1 40/128
7578, 2-2 R.ALLVWTGPGAGSVTFGELDAR.A 1841.8 1 28/40
7834, 1-2 R.ALLVWTGPGAGSVTFGELDAR.A 2212.9 1 29/40
7976, 1 R.ALLVWTGPGAGSVTFGELDAR.A 2142.3 1 26/40
8105, 1 R.WKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGK.V
1383.0 1 37/144
8261, 1 R.DNQGFCIPVGLGEPGLLLTK.V 547.7 1 18/38
8262, 1 K.GENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGK.V
747.0 1 31/136
8865, 2-2 R.EGFNVGIVVDPLFVLDNR.A 732.8 1 18/34
9143, 1-2 R.EGFNVGIVVDPLFVLDNR.A 542.3 1 15/34
18 ATP synthase subunit alpha, mitochondrial precursor 59750.3 4757810
18 (18
0 0 0 0)
4646, 2-2 R.VVDALGNAIDGK.G 1143.4 1 18/22
4944, 2-2 R.VVDALGNAIDGKGPIGSK.T 895.0 1 19/34
5144, 2-2 K.HALIIYDDLSK.Q 1585.0 1 18/20
5188, 1-2 R.ILGADTSVDLEETGR.V 2067.0 1 22/28
5274, 1-2 K.HALIIYDDLSK.Q 1649.9 1 18/20
5304, 2-2 K.TGTAEMSSILEER.I 943.0 1 15/24
5577, 1-2 R.EAYPGDVFYLHSR.L 1051.7 1 18/24
5696, 1 R.EAYPGDVFYLHSR.L 974.3 1 17/24
5830, 1-2 K.TSIAIDTIINQK.R 1864.5 1 18/22
5924, 1 K.TSIAIDTIINQK.R 1434.5 1 17/22
6665, 2-2 R.TGAIVDVPVGEELLGR.V 779.1 1 20/30
7024, 1 R.TGAIVDVPVGEELLGR.V 856.8 1 20/30
7095, 1 K.FENAFLSHVVSQHQALLGTIR.A 1549.8 1 31/80
Page 61
7108, 1 K.FENAFLSHVVSQHQALLGTIR.A 1694.0 1 24/40
7428, 1-2 K.GMSLNLEPDNVGVVVFGNDK.L 531.0 1 18/38
7858, 2-2 K.LKEIVTNFLAGFEA.- 773.6 1 15/26
9128, 1 R.EVAAFAQFGSDLDAATQQLLSR.G 1035.8 1 29/84
9154, 1 R.EVAAFAQFGSDLDAATQQLLSR.G 872.1 1 21/42
19 probable saccharopine dehydrogenase 47151.1 55770836
18 (18
0 0 0 0)
4610, 1-2 K.SAIYGFGDQSNLRK.L 908.5 1 17/26
4880, 2-2 R.NVSNLKPVPLIGPK.L 791.2 1 18/26
4976, 2-2 K.QATVVLNCVGPYR.F 1288.0 1 18/24
5007, 2-2 R.LPWAVAGR.S 692.2 1 10/14
5014, 1-2 R.NVSNLKPVPLIGPK.L 871.8 1 19/26
5102, 1-2 K.QATVVLNCVGPYR.F 1323.4 1 18/24
5129, 2-2 K.AGGVFTPGAAFSK.T 976.2 1 19/24
5265, 1-2 K.AGGVFTPGAAFSK.T 914.7 1 18/24
5266, 1-2 K.SAIYGFGDQSNLR.K 1284.7 1 19/24
8094, 1 K.AADKGVYIIGSSGFDSIPADLGVIYTR.N
910.7 1 23/52
8242, 1 K.QIDAASFTLTFFGQGYSQGTGTDK.N
888.1 1 20/46
8248, 1 K.QIDAASFTLTFFGQGYSQGTGTDK.N
1314.2 1 32/92
8454, 1-2 K.GVYIIGSSGFDSIPADLGVIYTR.N 584.4 1 22/44
8558, 1 K.MNGTLTAVESFLTIHSGPEGLSIHDGTWK.S
681.4 1 28/112
9453, 1 R.YLYENLEESPVQYAAYVTVGGITSVIK.L
677.3 1 18/52
9456, 1 R.YLYENLEESPVQYAAYVTVGGITSVIK.L
1288.1 1 36/104
10226, 1 K.GPEAGYVATPIAMVQAAMTLLSDASHLPK.A
855.3 1 32/112
10240, 1 K.GPEAGYVATPIAMVQAAMTLLSDASHLPK.A
958.6 1 21/56
20 trifunctional enzyme subunit alpha, mitochondrial precursor 82999.1 20127408
16 (16
0 0 0 0)
4402, 2-2 K.SEVSSDEDIQFR.L 1183.4 1 17/22
4877, 2-2 K.TLQEVTQLSQEAQR.I 1622.9 1 19/26
5004, 1-2 K.TLQEVTQLSQEAQR.I 615.5 2 19/26
5187, 1 K.TLQEVTQLSQEAQR.I 1534.0 1 18/26
5235, 2-2 K.GFYIYQEGVK.R 962.2 1 15/18
5292, 1-2 K.ALMGLYHGQVLCK.K 1297.8 1 16/24
6099, 2-2 R.FGGGNPELLTQMVSK.G 749.8 1 20/28
6273, 1-2 R.FGGGNPELLTQMVSK.G 925.1 1 21/28
7082, 2-2 K.LTAYAMTIPFVR.Q 931.5 1 15/22
7256, 1 K.MQLLEIITTEK.T 1547.6 1 18/20
7289, 2-2 K.TVLGTPEVLLGALPGAGGTQR.L 540.4 1 20/40
7907, 1 R.DSIFSNLTGQLDYQGFEK.A 2230.9 1 25/34
8457, 1-2 R.TIEYLEEVAITFAK.G 752.4 1 15/26
8582, 1 R.TIEYLEEVAITFAK.G 1236.3 1 18/26
8646, 1-2 K.DLNSDMDSILASLK.L 1954.6 1 18/26
Page 62
8721, 1-2 K.ADM*VIEAVFEDLSLK.H 1642.8 1 20/28
21 lanosterol synthase isoform 2 82198.1
22417755
6
16 (16
0 0 0 0)
4094, 1-2 R.NPDGGFATYETK.R 849.9 1 17/22
4143, 2-2 K.SCAISYTSYR.N 1088.9 1 16/18
4216, 1-2 K.SCAISYTSYR.N 1231.7 1 17/18
4319, 2-2 K.LYEHIVADDRFTK.S 1224.7 1 17/24
4430, 1-2 K.LYEHIVADDRFTK.S 1215.2 1 17/24
5000, 2-2 R.IPLPAGYREEIVR.Y 507.7 1 13/24
5541, 2-2 R.WYVDGPASTAFQEHVSR.I 1056.7 1 20/32
5577, 1 R.VVYALLNLYEHHHSAHLR.Q 785.7 1 28/68
5578, 1-2 R.ETLTQGLEFCR.R 603.7 1 13/20
5606, 2-2 R.LSAAEDPLVQSLR.Q 1021.2 1 18/24
5720, 2-2 R.ILGVGPDDPDLVR.A 901.2 1 18/24
5840, 1 R.LSAAEDPLVQSLR.Q 1446.5 1 20/24
6380, 2-2 R.NNVAPDELYTPHSWLLR.V 1263.7 1 22/32
6644, 1 R.NNVAPDELYTPHSWLLR.V 890.1 1 18/32
7539, 1 K.STVFGTALNYVSLR.I 1303.9 1 18/26
8796, 1 K.MQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQK.A
580.0 1 30/140
22 very long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2
precursor 68058.1 76496475
15 (15
0 0 0 0)
5512, 2-2 R.ALEQFATVVEAK.L 1342.2 1 16/22
5861, 2-2 K.ASNTAEVFFDGVR.V 1346.9 1 17/24
6176, 1 K.GIVNEQFLLQR.L 1225.0 1 15/20
6191, 1 R.FGMAAALAGTMR.G 1731.3 1 18/22
6304, 1 K.LASGETVAAFCLTEPSSGSDAASIR.T
1559.7 1 34/96
6504, 2-2 K.NPFGNAGLLLGEAGK.Q 1438.3 1 21/28
6778, 1 K.NPFGNAGLLLGEAGK.Q 1076.8 1 19/28
6863, 1 R.AGLGSGLSLSGLVHPELSR.S 1806.5 1 34/72
7857, 1 K.GQLTTDQVFPYPSVLNEEQTQFLK.E
999.7 1 34/92
7863, 1 K.GQLTTDQVFPYPSVLNEEQTQFLK.E
645.3 1 19/46
7934, 1 K.ELGAFGLQVPSELGGVGLCNTQYAR.L
638.3 1 21/48
7954, 1 K.ELGAFGLQVPSELGGVGLCNTQYAR.L
2061.6 1 40/96
9396, 1 R.LADGAIDLYAMVVVLSR.A 1416.8 1 19/32
9512, 1 K.LWISNGGLADIFTVFAK.T 1542.5 1 22/32
9800, 1 K.LWISNGGLADIFTVFAK.T 998.9 1 17/32
23 estradiol 17-beta-dehydrogenase 11 32935.6
14297672
9
21 (21
0 0 0 0)
4498, 1-2 K.VHTFVVDCSNREDIYSSAK.K 1255.9 1 21/36
5472, 1-2 K.NPSTSLGPTLEPEEVVNR.L 703.0 1 18/34
5567, 2-2 K.SKLVLWDINK.H 1290.0 1 15/18
5618, 1 K.NPSTSLGPTLEPEEVVNR.L 1011.4 1 22/34
5704, 1 R.KSVTGEIVLITGAGHGIGR.L 914.1 1 22/36
5717, 1-2 K.SKLVLWDINK.H 1333.0 1 15/18
Page 63
5720, 1 R.KSVTGEIVLITGAGHGIGR.L 2112.6 1 35/72
5907, 1 K.LVLWDINKHGLEETAAK.C 789.0 1 17/32
6279, 2-2 K.SVTGEIVLITGAGHGIGR.L 791.0 1 19/34
6452, 1-2 K.SVTGEIVLITGAGHGIGR.L 1764.5 1 25/34
6531, 1 K.SVTGEIVLITGAGHGIGR.L 698.7 1 17/34
7070, 2-2 K.TLTDELAALQITGVK.T 2470.5 1 22/28
7305, 1-2 K.TLTDELAALQITGVK.T 2534.5 1 22/28
7883, 1-2 K.SVTGEIVLITGAGHGIGR.L 1712.3 1 22/34
7892, 1 K.TFEVNVLAHFWTTK.A 1959.7 1 21/26
7992, 1 K.SVTGEIVLITGAGHGIGR.L 1257.4 1 21/34
8270, 1 K.VKAEIGDVSILVNNAGVVYTSDLFATQDPQIEK.T
1775.6 1 39/128
8907, 1-2 K.M*IFIPSSIAFLTTLER.I 742.9 1 19/30
8984, 1 K.M*IFIPSSIAFLTTLER.I 1213.6 1 24/30
9059, 2-2 K.MIFIPSSIAFLTTLER.I 943.0 1 22/30
9603, 1 K.TLTDELAALQITGVK.T 1052.3 1 16/28
24 peroxisomal bifunctional enzyme isoform 2 69153.5
26187853
9
17 (17
0 0 0 0)
4514, 1-2 R.TISQDEILER.C 742.9 1 16/18
4527, 2-2 K.VVNSDPVEEAIR.F 945.0 1 18/22
4641, 1-2 K.VVNSDPVEEAIR.F 1079.4 1 19/22
4664, 2-2 R.IPVIAVDSDKNQLATANK.M 1104.6 1 19/34
4743, 2-2 R.KGQGLTGPTLLPGTPAR.K 885.7 1 19/32
4810, 1-2 R.IPVIAVDSDKNQLATANK.M 2237.8 1 26/34
4881, 1-2 R.KGQGLTGPTLLPGTPAR.K 999.5 1 20/32
4894, 1-2 K.GWYQYDKPLGR.I 547.9 1 14/20
5564, 1 K.GQGLTGPTLLPGTPAR.K 615.3 1 18/30
6389, 1 R.VSDLAGLDVGWK.S 1689.3 1 20/22
6396, 1 R.VSDLAGLDVGWK.S 1640.8 1 20/22
7191, 2-2 K.GGPMFYASTVGLPTVLEK.L 1101.4 1 20/34
7247, 2-2 R.YCPIPDVLCELGR.F 804.5 1 18/24
7485, 1-2 R.YCPIPDVLCELGR.F 658.8 1 16/24
7497, 1-2 R.LTGVPAALDLITSGR.R 536.8 1 20/28
7562, 1-2 R.CLYSLINEAFR.I 1557.9 1 17/20
7682, 1 R.CLYSLINEAFR.I 1816.3 1 17/20
25 UDP-glucuronosyltransferase 2B7 precursor 60720.3
19019438
9
16 (16
0 0 0 0)
5213, 2-2 K.IEIYPTSLTK.T 996.7 1 15/18
5936, 1-2 K.ADVWLIR.N 881.4 3 11/12
6485, 2-2 R.ANVIASALAQIPQK.V 650.7 1 15/26
6591, 2-2 K.VLVWAAEYSHWM*NIK.T 614.8 1 16/28
6656, 2-2 K.TILDELIQR.G 704.8 1 14/16
6663, 2-2 K.WDQFYSEVLGRPTTLSETMGK.A 586.1 1 18/40
6681, 1-2 R.ANVIASALAQIPQK.V 856.5 1 17/26
6809, 1-2 K.TELENFIM*QQIK.R 597.6 1 13/22
6884, 2-2 R.VDFNTMSSTDLLNALKR.V 937.7 1 20/32
6978, 1 K.TILDELIQR.G 740.0 1 14/16
7106, 1-2 R.VDFNTMSSTDLLNALKR.V 771.5 1 18/32
7110, 1-2 R.VDFNTMSSTDLLNALKR.V 734.3 1 18/32
7305, 2-2 K.TELENFIMQQIK.R 1416.4 1 16/22
7623, 1-2 R.VDFNTMSSTDLLNALK.R 956.5 1 19/30
Page 64
7631, 1-2 R.VDFNTMSSTDLLNALK.R 925.9 1 19/30
8902, 1 R.NSWNFQFPYPLLPNVDFVGGLHCK.P
748.0 1 29/92
26 dimethylaniline monooxygenase [N-oxide-forming] 3 60033.2 50541961
21 (21
0 0 0 0)
4911, 2-2 K.HPDFATTGQWDVTTER.D 784.9 1 19/30
5050, 1-2 K.HPDFATTGQWDVTTER.D 688.5 1 18/30
5312, 2-2 R.SCLEEGLEPTCFEK.S 1402.3 1 22/26
5468, 1-2 R.SCLEEGLEPTCFEK.S 1184.5 1 21/26
5616, 2-2 R.NNEIILFK.G 808.9 1 11/14
5620, 2-2 R.NNEIILFK.G 1285.9 1 13/14
5750, 1-2 R.NNEIILFK.G 819.0 1 11/14
6316, 1-2 K.IQEYIIAFAK.E 952.1 1 16/18
6377, 2-2 K.VAIIGAGVSGLASIR.S 1993.8 1 21/28
6626, 2-2 R.VLVVGLGNSGCDIATELSR.T 2091.4 1 26/36
6838, 1-2 R.VLVVGLGNSGCDIATELSR.T 2209.6 1 24/36
6958, 1 R.VLVVGLGNSGCDIATELSR.T 2130.1 1 25/36
7628, 2-2 R.KEPVFNDELPASILCGIVSVKPNVK.E
2069.1 1 34/96
7874, 1-2 R.KEPVFNDELPASILCGIVSVKPNVK.E
1668.4 1 34/96
8007, 1 R.KEPVFNDELPASILCGIVSVKPNVK.E
1253.2 1 30/96
8289, 1-2 K.PNIPWLFLTDPK.L 695.5 1 17/22
8415, 1 K.PNIPWLFLTDPK.L 562.4 1 16/22
8498, 1 K.EPVFNDELPASILCGIVSVKPNVK.E 583.6 1 29/92
8710, 1-2 R.VWDNGYPWDMLLVTR.F 667.5 1 19/28
9564, 1-2 K.VAIIGAGVSGLASIR.S 552.3 1 15/28
11880, 2-2 K.VAIIGAGVSGLASIR.S 538.9 2 13/28
27 perilipin-2 48075.1 34577059
24 (24
0 0 0 0)
5252, 2-2 K.KVEGFDLVQKPSYYVR.L 1633.4 1 23/30
5404, 1-2 K.KVEGFDLVQKPSYYVR.L 1087.3 1 19/30
5468, 2-2 R.LPILNQPSTQIVANAK.G 733.5 1 19/30
5656, 1-2 K.SVVSGSINTVLGSR.M 2331.0 1 21/26
5669, 1-2 K.SVVSGSINTVLGSR.M 2567.1 1 22/26
5676, 1 R.LPILNQPSTQIVANAK.G 781.7 1 19/30
5748, 2-2 K.SQQTISQLHSTVHLIEFAR.K 1756.0 1 36/72
5756, 1 K.SVVSGSINTVLGSR.M 1760.6 1 19/26
5757, 2-2 K.SQQTISQLHSTVHLIEFAR.K 1484.6 1 22/36
5768, 1 K.SVVSGSINTVLGSR.M 1967.8 1 21/26
5900, 1-2 K.SQQTISQLHSTVHLIEFAR.K 1200.6 1 28/72
5927, 1-2 K.SQQTISQLHSTVHLIEFAR.K 1029.7 1 19/36
5972, 1 K.SQQTISQLHSTVHLIEFAR.K 1584.1 1 23/36
6052, 1 K.DSVASTITGVMDK.T 1148.6 1 17/24
6096, 2-2 R.MMQLVSSGVENALTK.S 1538.8 1 22/28
6276, 1-2 R.MMQLVSSGVENALTK.S 1934.4 1 24/28
6358, 1 R.MMQLVSSGVENALTK.S 1743.7 1 22/28
6370, 1 R.MMQLVSSGVENALTK.S 1378.0 1 21/28
6730, 1-2 K.TITSVAMTSALPIIQK.L 917.4 1 18/30
7779, 2-2 K.SELLVEQYLPLTEEELEK.E 989.2 1 22/34
Page 65
7790, 1 K.LYLSWVEWK.R 844.9 1 14/16
8038, 1-2 K.SELLVEQYLPLTEEELEK.E 1226.1 1 23/34
9093, 1 R.VVNLPLVSSTYDLMSSAYLSTK.D 2009.2 1 26/42
9105, 1 R.VVNLPLVSSTYDLMSSAYLSTK.D 1964.0 1 26/42
28 alpha-actinin-4 104853.3 12025678
17 (17
0 0 0 0)
5426, 1-2 K.LSGSNPYTTVTPQIINSK.W 1217.2 1 20/34
5448, 1-2 R.TINEVENQILTR.D 1345.2 1 17/22
5571, 1 K.LSGSNPYTTVTPQIINSK.W 1655.8 1 23/34
5580, 2-2 R.FAIQDISVEETSAK.E 1093.5 1 19/26
5584, 1 R.TINEVENQILTR.D 1509.9 1 18/22
5883, 1-2 K.QLEAIDQLHLEYAK.R 661.1 1 16/26
6029, 2-2 R.ETTDTDTADQVIASFK.V 1116.4 1 19/30
6084, 1-2 K.ICDQWDALGSLTHSR.R 1391.0 1 20/28
6207, 1-2 R.ETTDTDTADQVIASFK.V 1799.8 1 21/30
6525, 1-2 K.EGLLLWCQR.K 686.2 1 13/16
7606, 2-2 K.AIMTYVSSFYHAFSGAQK.A 674.1 1 15/34
7833, 1-2 K.LASDLLEWIR.R 1074.0 1 15/18
7852, 1-2 K.AIMTYVSSFYHAFSGAQK.A 1138.8 1 20/34
7955, 1 K.AIMTYVSSFYHAFSGAQK.A 1015.4 1 20/34
7956, 1 K.LASDLLEWIR.R 1085.3 1 15/18
8374, 1-2 R.VGWEQLLTTIAR.T 927.2 1 16/22
8456, 1 R.VGWEQLLTTIAR.T 1462.6 1 18/22
29 long-chain-fatty-acid--CoA ligase 5 isoform a 82262.5 42794756
13 (13
0 0 0 0)
4175, 1-2 R.IVQAVVYSCGAR.V 1598.2 1 18/22
4830, 2-2 K.GSFEELCQNQVVR.E 1285.1 1 17/24
4959, 1-2 R.AEYLGSCLLHK.G 515.6 1 13/20
5338, 2-2 R.TQIDSLYEHIQD.- 900.5 1 16/22
5489, 1-2 R.TQIDSLYEHIQD.- 888.6 1 17/22
6489, 1-2 K.GAMITHQNIVSNAAAFLK.C 769.0 1 18/34
6503, 1-2 R.SQPVLQIFVHGESLR.S 903.8 1 20/28
6551, 1 R.SQPVLQIFVHGESLR.S 970.3 1 18/28
7054, 2-2 K.VIILMDPFDDDLKQR.G 543.4 1 17/28
7082, 1 R.HDSFWDKLIFAK.I 625.0 1 14/22
7293, 1-2 K.VIILMDPFDDDLKQR.G 638.7 1 18/28
7647, 1 K.SGIEILSLYDAENLGK.E 966.2 1 19/30
7725, 1 R.SSLVGVVVPDTDVLPSFAAK.L 956.7 1 25/38
30 very long-chain acyl-CoA synthetase isoform 1 70311.8
22749961
9
13 (13
0 0 0 0)
4472, 1-2 K.KDDVSIYYVSR.T 933.4 1 16/20
5370, 2-2 K.FSASQFWDDCRK.Y 674.8 1 12/22
5376, 2-2 K.FSASQFWDDCRK.Y 652.0 1 12/22
5681, 1-2 R.IQDTIEITGTFK.H 599.8 1 15/22
5964, 2-2 K.FSASQFWDDCR.K 1036.8 1 15/20
6369, 2-2 K.LFQHIADYLPSYAR.P 569.0 1 13/26
6370, 2-2 K.DALYFLDDTAK.M 991.4 1 16/20
6546, 1-2 K.DALYFLDDTAK.M 800.5 1 15/20
7308, 2-2 K.MYVPMTEDIYNAISAK.T 584.0 1 17/30
7425, 2-2 R.IWYGTGLTFVSGLK.A 785.8 1 17/26
7619, 1-2 R.SEVTFSTPALYIYTSGTTGLPK.A 521.7 1 18/42
Page 66
7793, 1 R.IWYGTGLTFVSGLK.A 994.8 1 18/26
9924, 1 K.VLLVSPELQAAVEEILPSLK.K 850.8 1 18/38
31 NADPH--cytochrome P450 reductase 77047.7
12713903
3
11 (11
0 0 0 0)
3608, 2-2 K.SYENQKPPFDAK.N 850.6 1 18/22
3681, 1-2 K.SYENQKPPFDAK.N 754.6 1 17/22
5303, 2-2 K.IRYESGDHVAVYPANDSALVNQLGK.I
1107.3 1 29/96
5547, 2-2 R.SDEDYLYREELAQFHR.D 1643.7 1 30/60
5578, 2-2 K.EVGETLLYYGCR.R 777.9 1 15/22
5716, 1 R.YESGDHVAVYPANDSALVNQLGK.I 1023.2 1 32/88
5738, 1-2 K.EVGETLLYYGCR.R 664.3 1 14/22
6076, 2-2 R.DGALTQLNVAFSR.E 1453.5 1 18/24
6593, 1 R.NIIVFYGSQTGTAEEFANR.L 2081.5 1 27/36
7748, 2-2 R.TNVLYELAQYASEPSEQELLRK.M 735.4 1 27/84
8680, 1 R.TNVLYELAQYASEPSEQELLR.K 890.5 1 30/80
32 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) 58946.8 20149621
12 (12
0 0 0 0)
4260, 1-2 R.GLCGTVLIHK.V 741.3 1 14/18
6392, 2-2 R.LEQPDPGAVAAAAILR.A 676.4 1 19/30
6704, 1-2 K.VAGALAEAGVGLEEIAK.Q 2345.7 1 25/32
6918, 2-2 R.VCSTLLGLEEHLNALDR.A 595.7 1 16/32
7137, 1-2 R.VCSTLLGLEEHLNALDR.A 641.5 1 16/32
7150, 1-2 K.SPGADLLQVLTK.A 2271.3 1 19/22
7216, 1-2 K.LIDAETTAAAWPNVAAVSITGR.K 541.7 1 18/42
8411, 1-2 K.MGGSSGALYGLFLTAAAQPLK.A 1337.7 1 22/40
8446, 1-2 R.AEGIPVEMVVIGDDSAFTVLK.K 1017.2 1 22/40
8506, 1 K.MGGSSGALYGLFLTAAAQPLK.A 1007.3 1 20/40
8564, 1 R.AEGIPVEMVVIGDDSAFTVLK.K 822.8 1 21/40
9012, 1-2 R.TMLDSLWAAGQELQAWK.S 1336.8 1 20/32
33 dehydrogenase/reductase SDR family member 1 33908.8
20986290
1
23 (23
0 0 0 0)
4462, 1-2 K.SAFSSAETTELSGK.C 1960.5 1 21/26
5342, 1 R.VVAQEAQSLGGQCVPVVCDSSQESEVR.S
1104.4 1 35/104
5360, 1 R.VVAQEAQSLGGQCVPVVCDSSQESEVR.S
1120.0 1 23/52
6627, 2-2 K.WIIALYTSK.F 695.7 1 14/16
6651, 2-2 K.CVVALATDPNILSLSGK.V 2671.1 1 26/32
6677, 2-2 K.CVVALATDPNILSLSGK.V 2222.2 1 24/32
6864, 1-2 K.CVVALATDPNILSLSGK.V 2876.5 1 26/32
6917, 1 K.WIIALYTSK.F 779.5 1 15/16
6974, 1 K.CVVALATDPNILSLSGK.V 2543.4 1 25/32
7430, 2-2 R.HGVSCVSLWPGIVQTELLK.E 879.3 1 21/36
7659, 2-2 K.WIIALYTSKF.- 890.5 1 14/18
7690, 1-2 R.HGVSCVSLWPGIVQTELLK.E 1244.5 1 24/36
7700, 1-2 R.HGVSCVSLWPGIVQTELLK.E 1290.3 1 28/72
7784, 1 R.HGVSCVSLWPGIVQTELLK.E 1444.6 1 26/36
7796, 1 R.HGVSCVSLWPGIVQTELLK.E 1609.4 1 33/72
7802, 1 R.HGVSCVSLWPGIVQTELLK.E 1013.8 1 23/36
Page 67
7815, 2-2 R.LDVLVNNAYAGVQTILNTR.N 2022.2 1 31/72
8080, 1-2 R.LDVLVNNAYAGVQTILNTR.N 2618.5 1 26/36
8204, 1 R.LDVLVNNAYAGVQTILNTR.N 1534.5 1 26/36
8278, 2-2 K.AFWETPASMWDDINNVGLR.G 620.9 1 18/36
8304, 1 R.LDVLVNNAYAGVQTILNTR.N 631.2 1 17/36
8604, 1 R.EQQGRLDVLVNNAYAGVQTILNTR.N
889.0 1 27/92
9683, 1 K.CVVALATDPNILSLSGK.V 541.7 1 14/32
34 UTP--glucose-1-phosphate uridylyltransferase isoform a 56939.9 48255966
23 (23
0 0 0 0)
3922, 2-2 K.IQRPPEDSIQPYEK.I 1044.8 1 25/52
3924, 2-2 K.IQRPPEDSIQPYEK.I 555.4 1 16/26
3998, 1-2 K.IQRPPEDSIQPYEK.I 1382.5 1 26/52
4228, 2-2 R.INKESLLPVAK.D 1441.1 1 17/20
4308, 1-2 R.INKESLLPVAK.D 1620.6 1 18/20
4544, 2-2 R.LVEIAQVPK.A 1116.0 1 15/16
4653, 1-2 R.LVEIAQVPK.A 1016.7 1 14/16
5634, 2-2 K.SFENSLGINVPR.S 1129.9 1 16/22
5782, 1-2 K.SFENSLGINVPR.S 867.1 1 14/22
5807, 2-2 K.GTVIIIANHGDRIDIPPGAVLENK.I 1189.3 1 30/92
5912, 1 K.SFENSLGINVPR.S 1317.2 1 17/22
5967, 1-2 K.GTVIIIANHGDRIDIPPGAVLENK.I 1156.2 1 34/92
7634, 2-2 R.NENTFLDLTVQQIEHLNK.T 1606.7 1 21/34
7779, 1-2 K.TYNTDVPLVLMNSFNTDEDTK.K 574.1 1 17/40
7870, 1-2 R.NENTFLDLTVQQIEHLNK.T 1707.7 1 22/34
7876, 1-2 R.NENTFLDLTVQQIEHLNK.T 827.8 1 27/68
7882, 1-2 R.NENTFLDLTVQQIEHLNK.T 1442.0 1 21/34
7923, 2-2 K.IFNTNNLWISLAAVK.R 1863.9 1 21/28
7994, 1 R.NENTFLDLTVQQIEHLNK.T 1038.3 1 18/34
8156, 2-2 K.TLDGGLNVIQLETAVGAAIK.S 1132.2 1 22/38
8421, 1-2 R.NENTFLDLTVQQIEHLNK.T 523.7 1 14/34
8483, 1 K.TLDGGLNVIQLETAVGAAIK.S 648.0 1 17/38
8523, 1 K.TLDGGLNVIQLETAVGAAIK.S 1920.6 1 33/76
35 cytochrome P450 2E1 precursor 56848.6 10834998
14 (14
0 0 0 0)
4007, 1-2 K.FKPEHFLNENGK.F 678.6 1 16/22
5228, 2-2 R.EAHFLLEALRK.T 1369.5 1 16/20
5285, 2-2 R.DLTDCLLVEM*EKEK.H 569.5 1 15/26
5364, 1-2 R.EAHFLLEALRK.T 1285.6 1 15/20
5795, 2-2 R.GIIFNNGPTWK.D 1228.0 1 16/20
6105, 2-2 K.DRQEMPYMDAVVHEIQR.F 724.9 1 28/64
6759, 2-2 R.DLTDCLLVEMEKEK.H 1703.3 1 21/26
6874, 2-2 R.FGPVFTLYVGSQR.M 1900.3 1 19/24
6959, 1-2 R.DLTDCLLVEMEKEK.H 506.2 1 13/26
7013, 2-2 K.DIDLSPIHIGFGCIPPR.Y 549.4 1 15/32
7095, 1-2 R.FGPVFTLYVGSQR.M 1657.2 1 19/24
7419, 2-2 K.GTVVVPTLDSVLYDNQEFPDPEK.F 1079.7 1 22/44
7683, 1-2 K.GTVVVPTLDSVLYDNQEFPDPEK.F 1498.5 1 24/44
7809, 1 K.GTVVVPTLDSVLYDNQEFPDPEK.F 519.0 1 17/44
36 formimidoyltransferase-cyclodeaminase 58926.2 11140815 13 (13
Page 68
0 0 0 0)
6039, 1-2 R.GVSVDECVLCAQAFGQR.L 584.4 1 15/32
6122, 1-2 K.TQAALVLDCLETRQE.- 1343.1 1 19/28
6135, 1-2 K.TQAALVLDCLETRQE.- 1394.3 1 19/28
6496, 2-2 R.LGLDSLCPFSPK.E 1139.5 1 16/22
6676, 1-2 R.LGLDSLCPFSPK.E 1466.1 1 18/22
7077, 1-2 R.MGALDVCPFIPVR.G 938.6 1 17/24
7977, 1 R.KFLIAFNINLLGTK.E 1769.8 1 21/26
7978, 1-2 R.TVYTFVGPPECVVEGALNAAR.V 525.0 1 19/40
8075, 1 R.TVYTFVGPPECVVEGALNAAR.V 503.8 1 19/40
8124, 1 K.LQQADWAPDFGPSSFVPSWGATATGAR.K
810.7 1 32/104
8660, 1-2 R.EAQELSLPVVGSQLVGLVPLK.A 1290.1 1 27/40
8746, 1 R.EAQELSLPVVGSQLVGLVPLK.A 1177.1 1 26/40
9958, 1 K.NLAQVSTNLLDFEVTALHTVYEETCR.E
702.3 1 17/50
37 tubulin alpha-1A chain 50135.3 17986283
14 (14
0 0 0 0)
5342, 2-2 R.QLFHPEQLITGKEDAANNYAR.G 1833.2 1 35/80
5502, 2-2 R.QLFHPEQLITGK.E 543.9 1 15/22
5586, 1 R.QLFHPEQLITGKEDAANNYAR.G 1080.0 1 30/80
5633, 2-2 K.VGINYQPPTVVPGGDLAK.V 559.0 1 20/34
5667, 1-2 R.QLFHPEQLITGK.E 696.4 1 17/22
5801, 1-2 K.VGINYQPPTVVPGGDLAK.V 541.2 1 19/34
6287, 2-2 R.AVCM*LSNTTAIAEAWAR.L 1320.0 1 20/32
6412, 2-2 R.IHFPLATYAPVISAEK.A 752.9 1 19/30
6604, 1-2 R.IHFPLATYAPVISAEK.A 766.9 1 19/30
6719, 1 R.IHFPLATYAPVISAEK.A 707.6 1 19/30
6840, 1 K.TIGGGDDSFNTFFSETGAGK.H 1512.8 1 23/38
7256, 1-2 R.AVFVDLEPTVIDEVR.T 630.8 1 18/28
7374, 1-2 R.AVCMLSNTTAIAEAWAR.L 1065.4 1 25/64
8252, 1 R.FDGALNVDLTEFQTNLVPYPR.I 891.9 1 20/40
38 serum albumin preproprotein 69366.4 4502027
14 (14
0 0 0 0)
4226, 1-2 R.FKDLGEENFK.A 1035.1 1 16/18
4562, 1 K.VHTECCHGDLLECADDRADLAK.Y 870.9 1 32/84
4827, 2-2 K.KVPQVSTPTLVEVSR.N 764.1 1 17/28
5133, 1 K.KVPQVSTPTLVEVSR.N 877.7 1 19/28
5895, 1 R.RPCFSALEVDETYVPK.E 520.2 1 16/30
6058, 2-2 K.SLHTLFGDKLCTVATLR.E 645.3 1 15/32
6116, 2-2 K.QNCELFEQLGEYK.F 1249.1 1 18/24
6250, 1 K.SLHTLFGDKLCTVATLR.E 1539.7 1 23/32
6268, 1 K.SLHTLFGDKLCTVATLR.E 1479.4 1 22/32
6366, 1 K.QNCELFEQLGEYK.F 1296.4 1 18/24
7160, 1 K.VFDEFKPLVEEPQNLIK.Q 1307.9 1 32/64
7690, 1 R.RHPYFYAPELLFFAK.R 1590.2 1 30/56
9092, 1 K.ALVLIAFAQYLQQCPFEDHVK.L 1358.7 1 20/40
9110, 1 K.ALVLIAFAQYLQQCPFEDHVK.L 1296.2 1 31/80
39 calcium-binding mitochondrial carrier protein Aralar2 isoform 2 74175.1 7657581
15 (15
0 0 0 0)
5230, 2-2 K.DVEVTKEEFVLAAQK.F 2242.0 1 23/28
Page 69
5498, 2-2 K.LAVATFAGIENK.F 1873.3 1 19/22
5638, 1-2 K.LAVATFAGIENK.F 1525.7 1 18/22
6180, 2-2 R.PVLLQVAESAYR.F 1555.0 1 18/22
6254, 2-2 K.ASGDSARPVLLQVAESAYR.F 1166.1 1 27/72
6339, 1-2 R.PVLLQVAESAYR.F 1289.9 1 18/22
6462, 1-2 K.ASGDSARPVLLQVAESAYR.F 571.8 1 19/36
7007, 2-2 R.IAPLEEGTLPFNLAEAQR.Q 760.4 1 22/34
7205, 1-2 R.IAPLEEGTLPFNLAEAQR.Q 791.7 1 23/34
7336, 1 R.IAPLEEGTLPFNLAEAQR.Q 842.1 1 22/34
7356, 1-2 R.DLGFFGIYK.G 610.1 1 13/16
7438, 1-2 R.DIPFSAIYFPCYAHVK.A 546.5 1 14/30
7654, 1-2 K.FGLYLPLFKPSVSTSK.A 526.6 1 18/30
8004, 2-2 R.FGLGSVAGAVGATAVYPIDLVK.T 958.2 1 20/42
8296, 1-2 R.FGLGSVAGAVGATAVYPIDLVK.T 1038.6 1 21/42
40 methyltransferase-like protein 7A precursor 28318.9 89145417
29 (29
0 0 0 0)
4424, 1-2 R.VTCIDPNPNFEK.F 781.1 1 16/22
4533, 2-2 R.FTVIYNEQM*ASK.K 1051.0 1 18/22
4628, 1 R.VTCIDPNPNFEK.F 715.3 1 16/22
4646, 1-2 R.FTVIYNEQM*ASK.K 859.8 1 17/22
4989, 2-2 R.FTVIYNEQMASK.K 843.0 1 17/22
5123, 1-2 R.FTVIYNEQMASK.K 977.7 1 18/22
5306, 1 R.FTVIYNEQMASK.K 878.0 1 17/22
5950, 1-2 K.RELFSNLQEFAGPSGK.L 833.6 1 18/30
6027, 1 K.RELFSNLQEFAGPSGK.L 581.4 2 14/30
6248, 2-2 K.LQHIQAPLSWELVR.P 3473.3 1 32/52
6308, 2-2 K.LSLLEVGCGTGANFK.F 1377.2 1 20/28
6356, 2-2 R.ELFSNLQEFAGPSGK.L 617.9 1 15/28
6410, 1-2 K.LSLLEVGCGTGANFK.F 1726.2 1 23/28
6416, 2-2 R.ELFSNLQEFAGPSGK.L 1380.7 1 19/28
6417, 1 K.LSLLEVGCGTGANFK.F 1122.2 1 18/28
6422, 2-2 K.LQHIQAPLSWELVRPHIYGYAVK.- 816.5 1 30/88
6443, 1-2 K.LQHIQAPLSWELVR.P 882.5 1 17/26
6490, 1 K.LQHIQAPLSWELVR.P 2972.8 1 31/52
6497, 1 K.LQHIQAPLSWELVR.P 1428.7 1 21/26
6584, 1-2 R.ELFSNLQEFAGPSGK.L 1713.2 1 21/28
6599, 1 K.LQHIQAPLSWELVRPHIYGYAVK.- 719.3 1 18/44
6614, 1 K.LQHIQAPLSWELVRPHIYGYAVK.- 787.3 1 32/88
6627, 1-2 K.LQHIQAPLSWELVRPHIYGYAVK.- 935.3 1 31/88
6668, 1 R.ELFSNLQEFAGPSGK.L 848.0 1 15/28
6672, 1 R.ELFSNLQEFAGPSGK.L 927.6 1 16/28
6735, 1 K.LSLLEVGCGTGANFK.F 1136.6 1 19/28
6771, 1 R.ELFSNLQEFAGPSGK.L 1603.1 1 20/28
7416, 1-2 -.M*ELTIFILR.L 775.1 2 13/16
10656, 1 K.LSLLEVGCGTGANFK.F 939.6 1 18/28
41 annexin A6 isoform 1 75872.8 71773329
12 (12
0 0 0 0)
3671, 1-2 K.GTVRPANDFNPDADAK.A 771.6 1 16/30
4931, 2-2 K.SLHQAIEGDTSGDFLK.A 1744.7 1 21/30
5225, 1 K.SLHQAIEGDTSGDFLK.A 2102.1 1 22/30
6288, 2-2 R.DAFVAIVQSVK.N 1934.2 1 18/20
Page 70
6365, 1-2 R.DLEADIIGDTSGHFQK.M 1377.6 1 22/30
6452, 1 R.DLEADIIGDTSGHFQK.M 1151.6 1 21/30
6467, 1-2 R.DAFVAIVQSVK.N 1818.9 1 17/20
6563, 1 K.CLIEILASR.T 718.7 1 14/16
6830, 1-2 R.LILGLMMPPAHYDAK.Q 524.3 1 16/28
7498, 2-2 K.WGTDEAQFIYILGNR.S 1994.4 1 22/28
7858, 1-2 K.GLGTDEDTIIDIITHR.S 1124.5 1 19/30
8326, 1 K.DLIADLKYELTGK.F 1328.1 1 18/24
42 programmed cell death 6-interacting protein isoform 1 96022.6 22027538
10 (10
0 0 0 0)
4382, 1-2 K.FIQQTYPSGGEEQAQYCR.A 522.1 1 20/34
4532, 1 K.FIQQTYPSGGEEQAQYCR.A 592.2 1 20/34
4559, 1-2 R.LLDEEEATDNDLR.A 1604.5 1 19/24
5243, 2-2 K.DAFDKGSLFGGSVK.L 806.8 1 17/26
5387, 1-2 K.LALASLGYEK.S 1273.2 1 15/18
5747, 1-2 K.MVPVSVQQSLAAYNQR.K 816.9 1 18/30
5861, 1-2 R.VPDLKDLDPIGK.A 756.6 2 16/22
6152, 2-2 K.LANQAADYFGDAFK.Q 1436.8 1 19/26
6746, 1 R.SVIEQGGIQTVDQLIK.E 885.6 1 16/30
7258, 2-2 K.FYNELTEILVR.F 1540.6 1 18/20
43 fatty aldehyde dehydrogenase isoform 1 57669.1 73466520
14 (13
1 0 0 0)
4510, 1-2 K.EFYGENIKESPDYER.I 818.7 1 16/28
4676, 1 K.EFYGENIKESPDYER.I 734.8 1 14/28
5434, 1 K.SPCYIDKDCDLDIVCR.R 1290.6 1 21/30
5444, 1-2 R.ILSLLEGQK.I 552.1 2 13/16
5679, 2-2 R.YIAPTVLTDVDPK.T 1050.3 1 18/24
5800, 1-2 R.YIAPTVLTDVDPK.T 1184.6 1 19/24
5858, 2-2 K.NVDEAINFINER.E 1872.8 1 19/22
5922, 1 R.YIAPTVLTDVDPK.T 737.4 1 16/24
6111, 1 K.NVDEAINFINER.E 1422.2 1 16/22
7293, 2-2 R.EKDILTAIAADLCK.S 1367.3 1 19/26
7520, 1-2 R.EKDILTAIAADLCK.S 1656.5 1 20/26
7623, 1 R.EKDILTAIAADLCK.S 1132.9 1 18/26
7756, 2-2 K.VM*QEEIFGPILPIVPVK.N 683.4 1 14/32
8256, 2-2 K.DILTAIAADLCK.S 1164.2 1 17/22
44 78 kDa glucose-regulated protein precursor 72332.5 16507237
12 (12
0 0 0 0)
4469, 2-2 R.TWNDPSVQQDIK.F 1013.5 1 17/22
4590, 1-2 R.TWNDPSVQQDIK.F 976.2 1 17/22
4862, 2-2 K.NQLTSNPENTVFDAK.R 846.8 1 18/28
5045, 1 K.LYGSAGPPPTGEEDTAEKDEL.- 904.1 1 20/40
5049, 2-2 K.SQIFSTASDNQPTVTIK.V 1416.7 1 20/32
5213, 1-2 K.SQIFSTASDNQPTVTIK.V 1243.9 1 22/32
5344, 1 K.SQIFSTASDNQPTVTIK.V 920.8 1 20/32
5538, 1 K.VTHAVVTVPAYFNDAQR.Q 622.6 1 18/32
5848, 2-2 K.SDIDEIVLVGGSTR.I 950.4 1 16/26
5949, 1-2 R.IINEPTAAAIAYGLDKR.E 1019.9 1 20/32
6014, 1 R.IINEPTAAAIAYGLDKR.E 1121.6 1 21/32
6656, 1-2 R.AKFEELNMDLFR.S 1231.1 1 17/22
45 amine oxidase [flavin-containing] B 58762.6 38202207 11 (11
Page 71
0 0 0 0)
4739, 2-2 K.YVDLGGSYVGPTQNR.I 948.1 1 21/28
4749, 2-2 K.LERPVIYIDQTR.E 1076.6 1 17/22
4853, 1-2 K.YVDLGGSYVGPTQNR.I 921.8 1 19/28
4868, 1-2 K.LERPVIYIDQTR.E 945.0 1 16/22
5650, 2-2 R.ENVLVETLNHEM*YEAK.Y 624.7 1 17/30
5688, 2-2 K.ELLDKLCWTESAK.Q 1136.2 1 19/24
5895, 2-2 K.VLGSLEALEPVHYEEK.N 878.5 1 16/30
5974, 1 K.LLHDSGLNVVVLEAR.D 950.3 1 21/28
6063, 1-2 K.VLGSLEALEPVHYEEK.N 946.3 1 17/30
6256, 2-2 K.YVISAIPPTLGMK.I 750.9 1 16/24
6581, 2-2 R.ENVLVETLNHEMYEAK.Y 1512.8 1 19/30
46 prelamin-A/C isoform 1 precursor 74139.0 27436946
8 (7 1 0
0 0)
4013, 1-2 K.AAYEAELGDAR.K 1537.0 1 17/20
4424, 1 K.ASASGSGAQVGGPISSGSSASSVTVTR.S
660.8 1 21/52
4738, 1 R.VAVEEVDEEGKFVR.L 723.2 1 15/26
5138, 1-2 R.TLEGELHDLRGQVAK.L 537.2 1 16/28
5164, 1-2 R.LADALQELR.A 1105.8 1 15/16
5822, 1-2 R.LKDLEALLNSK.E 1388.5 2 16/20
6226, 1 R.IRIDSLSAQLSQLQK.Q 994.3 1 17/28
7052, 1-2 R.MQQQLDEYQELLDIK.L 2038.2 1 22/28
47 endoplasmin precursor 92468.2 4507677
13 (12
0 0 0 1)
4002, 1-2 K.SREGSRTDDEVVQR.E 694.6 3 14/26
4937, 2-2 K.IADDKYNDTFWK.E 1326.3 1 17/22
5061, 1-2 K.IADDKYNDTFWK.E 1203.5 1 17/22
5112, 2-2 R.FQSSHHPTDITSLDQYVER.M 1845.1 1 32/72
5408, 1 R.FQSSHHPTDITSLDQYVER.M 742.9 1 19/36
5488, 1-2 K.GVVDSDDLPLNVSR.E 967.4 1 19/26
5612, 1 K.GVVDSDDLPLNVSR.E 1245.3 1 21/26
5762, 2-2 K.SILFVPTSAPR.G 1026.0 1 18/20
6466, 1 R.LISLTDENALSGNEELTVK.I 655.1 1 18/36
8094, 2-2 K.YSQFINFPIYVWSSK.T 586.9 1 14/28
8116, 2-2 K.YSQFINFPIYVWSSK.T 603.4 1 13/28
8369, 1-2 K.YSQFINFPIYVWSSK.T 828.5 1 15/28
9934, 1 R.IKEDEDDKTVLDLAVVLFETATLR.S 966.1 1 30/92
48 monoglyceride lipase isoform 1 34292.3 6005786
9 (9 0 0
0 0)
3852, 2-2 K.ALIFVSHGAGEHSGR.Y 535.5 1 14/28
5316, 2-2 R.NKTEVDIYNSDPLICR.A 952.2 1 20/30
6170, 1 R.MVVSDFHVFVR.D 871.3 2 14/20
6741, 2-2 K.GAYLLMELAK.S 1120.1 1 14/18
6766, 2-2 R.RTPQSIPYQDLPHLVNADGQYLFCR.Y
972.8 1 29/96
7089, 1 R.RTPQSIPYQDLPHLVNADGQYLFCR.Y
1278.0 1 34/96
7708, 2-2 K.LTVPFLLLQGSADR.L 552.8 1 15/26
7979, 1-2 K.LTVPFLLLQGSADR.L 842.7 1 18/26
8828, 1 K.VLNLVLPNLSLGPIDSSVLSR.N 1441.1 1 32/80
Page 72
49 aldehyde dehydrogenase family 8 member A1 isoform 3 48035.6
30150069
8
8 (8 0 0
0 0)
3791, 2-2 R.VPNSGKDEIEAAVK.A 901.4 1 17/26
5852, 2-2 K.YGLAATVWSSNVGR.V 1047.5 1 20/26
5999, 1-2 K.YGLAATVWSSNVGR.V 859.3 1 18/26
6657, 1-2 R.VGEALVSHPEVPLISFTGSQPTAER.I
846.9 1 30/96
6855, 1-2 K.DSYDFFTEIK.T 929.9 1 14/18
7209, 1-2 K.NPAIIFEDANLDECIPATVR.S 1534.1 1 26/38
8606, 1 K.VGIPSDPLVSIGALISK.A 649.6 1 20/32
10005, 1 R.VLNQVADLLEQSLEEFAQAESK.D 1323.3 1 22/42
50 D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 38156.9 44680133
7 (7 0 0
0 0)
4414, 1-2 R.TVQLNVCSSEEVEK.V 968.6 1 17/26
6111, 1-2 K.QVAEVNLWGTVR.M 767.1 1 15/22
6167, 2-2 K.MWEELPEVVR.K 810.0 1 14/18
6297, 1 K.FGVEAFSDCLR.Y 763.0 1 15/20
7070, 1-2 R.TVQLNVCSSEEVEKVVEIVR.S 1231.8 1 21/38
8051, 1-2 K.VSVVEPGNFIAATSLYSPESIQAIAK.K
632.9 1 19/50
8156, 1-2 K.METYCSSGSTDTSPVIDAVTHALTATTPYTR.Y
892.5 1 32/120
51 acetyl-CoA carboxylase 2 precursor 276537.6
13414206
2
9 (9 0 0
0 0)
4824, 1-2 K.VLIANNGIAAVK.C 1165.4 1 17/22
4857, 2-2 K.EASFEYLQNEGER.L 940.2 1 15/24
4985, 1-2 K.EASFEYLQNEGER.L 671.5 1 14/24
5518, 2-2 R.VIQVENSHIILTGASALNK.V 1837.2 1 23/36
5825, 2-2 R.QILIASHLPSYELR.H 844.0 1 17/26
5835, 2-2 K.GTWQSGFFDHGSFK.E 715.5 1 15/26
5901, 2-2 K.FGAYIVDGLR.Q 858.1 1 14/18
6041, 1-2 K.FGAYIVDGLR.Q 802.5 1 14/18
6482, 1-2 R.KAESAEDFPILFR.Q 1262.7 1 18/24
52 talin-1 269764.4
22302941
0
8 (8 0 0
0 0)
4612, 1 R.LASEAKPAAVAAENEEIGSHIK.H 1961.9 1 33/84
6734, 1 K.AVAEQIPLLVQGVR.G 730.1 1 18/26
7294, 1 K.VGAIPANALDDGQWSQGLISAAR.M
818.0 1 22/44
7359, 1-2 K.EADESLNFEEQILEAAK.S 1113.7 1 19/32
7871, 1-2 K.AGFLDLKDFLPK.E 1073.3 1 14/22
7997, 1-2 K.TLAESALQLLYTAK.E 1543.0 1 19/26
9336, 1 R.GVGAAATAVTQALNELLQHVK.A 788.1 1 19/40
9378, 1 R.GVGAAATAVTQALNELLQHVK.A 576.8 1 16/40
53 protein diaphanous homolog 1 isoform 1 141346.4
11939575
8
9 (9 0 0
0 0)
3514, 2-2 K.LQDLQGEKDALHSEK.Q 1646.4 1 20/28
6120, 2-2 R.VQLNVFDEQGEEDSYDLK.G 515.8 1 17/34
6228, 2-2 K.LVAEDLSQDCFWTK.V 823.9 1 17/26
6495, 1 K.LVAEDLSQDCFWTK.V 748.0 1 15/26
7022, 1 K.AGCAVTSLLASELTK.D 1038.8 1 20/28
Page 73
7035, 1-2 K.QQIATEKQDLEAEVSQLTGEVAK.L 902.4 1 27/88
7599, 1-2 K.TAQNLSIFLGSFR.M 651.3 1 16/24
7733, 1 K.TAQNLSIFLGSFR.M 796.1 1 15/24
9212, 1 K.VGCLQLINALITPAEELDFR.V 855.4 1 20/38
54 C-1-tetrahydrofolate synthase, cytoplasmic 101530.5
22213663
9
8 (8 0 0
0 0)
5290, 2-2 K.TDTESELDLISR.L 1685.6 1 17/22
5476, 2-2 K.AYIQENLELVEK.G 1216.4 1 17/22
5686, 2-2 K.YVVVTGITPTPLGEGK.S 967.2 1 20/30
5866, 1 K.GCLELIKETGVPIAGR.H 1082.6 1 18/30
6243, 2-2 R.LDIDPETITWQR.V 964.8 1 17/22
6431, 1-2 R.LDIDPETITWQR.V 1079.5 1 18/22
7245, 1-2 R.AAQAPSSFQLLYDLK.L 862.8 1 20/28
7264, 1 R.EIGLLSEEVELYGETK.A 2170.2 1 23/30
55 cullin-associated NEDD8-dissociated protein 1 136374.7 21361794
12 (12
0 0 0 0)
5726, 2-2 K.ALTLIAGSPLK.I 1564.8 1 16/20
5819, 1-2 K.VIRPLDQPSSFDATPYIK.D 757.1 1 18/34
5871, 1-2 K.ALTLIAGSPLK.I 1178.4 1 15/20
6008, 2-2 R.AVAALLTIPEAEK.S 956.7 1 17/24
7535, 2-2 K.ADVFHAYLSLLK.Q 902.5 1 14/22
7685, 2-2 K.LGTLSALDILIK.N 842.7 1 18/22
7785, 1-2 K.ADVFHAYLSLLK.Q 1341.6 1 17/22
7820, 1-2 K.LTLIDPETLLPR.L 794.8 1 15/22
7919, 1 K.ADVFHAYLSLLK.Q 1527.8 1 17/22
8068, 1 K.LGTLSALDILIK.N 1002.0 1 18/22
8981, 2-2 K.ISGSILNELIGLVR.S 980.0 1 17/26
9245, 1 K.ISGSILNELIGLVR.S 1371.6 1 19/26
56 coatomer subunit alpha isoform 2 138344.7
14853685
3
8 (8 0 0
0 0)
3969, 2-2 K.YAVTTGDHGIIR.T 1864.6 1 19/22
5555, 2-2 R.SSGLTAVWVAR.N 1481.7 1 17/20
5828, 2-2 R.ASNLENSTYDLYTIPK.D 1664.9 1 22/30
6388, 1-2 K.SGAWDESGVFIYTTSNHIK.Y 677.3 1 18/36
6464, 1-2 R.TLDLPIYVTR.V 821.8 1 15/18
6608, 2-2 R.GITGVDLFGTTDAVVK.H 1455.7 1 21/30
6813, 1-2 R.GITGVDLFGTTDAVVK.H 1366.2 1 21/30
8907, 1 K.LSFLYLITGNLEK.L 1826.3 1 19/24
57 cytochrome P450 2A7 isoform 2 precursor 50666.4 15147328
9 (9 0 0
0 0)
5600, 2-2 K.KSDAFVPFSIGK.R 842.7 1 17/22
5727, 1-2 K.KSDAFVPFSIGK.R 1140.0 1 17/22
5896, 2-2 R.NYTMSFLPR.- 869.4 1 13/16
6225, 2-2 R.FGDVIPMSLAR.R 680.4 1 17/20
6442, 1-2 K.SDAFVPFSIGK.R 1022.6 1 16/20
6668, 2-2 K.MPYMEAVIHEIQR.F 1689.4 1 19/24
7350, 2-2 R.YGFLLLMK.H 849.5 1 12/14
7623, 2-2 R.TVSNVISSIVFGDR.F 1636.4 1 21/26
7996, 1 R.TVSNVISSIVFGDR.F 1507.4 1 21/26
58 perilipin-4 134430.4
12293719
5
8 (6 2 0
0 0)
Page 74
3714, 1-2 R.LDQGSGASAEDAAVQEER.D 1792.2 1 22/34
4644, 2-2 K.NTVCSGVTGAVNLAK.E 1275.3 1 17/28
4763, 1-2 K.NTVCSGVTGAVNLAK.E 1819.1 1 22/28
4763, 1-2 K.DTVTTGVM*GAVNLAK.G 659.0 2 16/28
4797, 1 R.ARPAADPTGAPAAEAAQPQAQVAAHPEQTAPWTEK.E
884.8 1 39/136
4899, 1 K.DAVTTGVTGAVNVAK.G 2280.7 1 23/28
4899, 1 K.DAVSTGLTGAVNVAK.G 1490.3 2 20/28
4954, 2-2 R.AKDAVSSGVASVVDVAK.G 964.2 1 19/32
59 succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 72691.1
15641600
3
9 (9 0 0
0 0)
4398, 2-2 R.TGHSLLHTLYGR.S 1246.3 1 17/22
4479, 1-2 R.TGHSLLHTLYGR.S 1531.4 1 18/22
4604, 2-2 K.VTLEYRPVIDK.T 1063.9 1 14/20
4725, 1-2 K.VTLEYRPVIDK.T 1086.0 1 15/20
5585, 1 R.HVNGQDQIVPGLYACGEAACASVHGANR.L
2275.9 1 38/108
5597, 1-2 R.HVNGQDQIVPGLYACGEAACASVHGANR.L
694.5 1 30/108
5898, 2-2 R.AAFGLSEAGFNTACVTK.L 1491.7 1 21/32
7803, 1 R.AGLPCQDLEFVQFHPTGIYGAGCLITEGCR.G
674.3 1 36/116
8926, 1-2 R.LGANSLLDLVVFGR.A 1466.6 1 19/26
60 cytochrome P450 2C9 precursor 55627.6 13699818
14 (14
0 0 0 0)
4004, 2-2 R.SHM*PYTDAVVHEVQR.Y 750.3 1 24/56
4449, 2-2 R.SHMPYTDAVVHEVQR.Y 728.7 1 18/28
6818, 2-2 R.YIDLLPTSLPHAVTCDIK.F 620.1 1 21/34
7017, 1-2 R.YIDLLPTSLPHAVTCDIK.F 704.8 1 22/34
7148, 1 R.YIDLLPTSLPHAVTCDIK.F 552.6 1 19/34
7545, 1-2 K.GTTILISLTSVLHDNK.E 809.9 1 15/30
7635, 1 K.GTTILISLTSVLHDNK.E 884.6 1 16/30
8162, 2-2 R.GKLPPGPTPLPVIGNILQIGIK.D 1146.0 1 27/84
8518, 1 R.GKLPPGPTPLPVIGNILQIGIK.D 1909.5 1 34/84
8810, 2-2 K.LPPGPTPLPVIGNILQIGIK.D 1428.1 1 30/76
8852, 2-2 K.LPPGPTPLPVIGNILQIGIK.D 838.0 1 23/38
9111, 1-2 K.LPPGPTPLPVIGNILQIGIK.D 927.9 1 24/38
9122, 1 K.LPPGPTPLPVIGNILQIGIK.D 1275.7 1 29/76
9146, 1 K.LPPGPTPLPVIGNILQIGIK.D 835.5 1 24/38
61 perilipin-3 isoform 1 47074.7
25595828
2
11 (11
0 0 0 0)
3261, 2-2 K.QLQGPEKEPPKPEQVESR.A 1150.7 1 29/68
3336, 1-2 K.QLQGPEKEPPKPEQVESR.A 1509.5 1 33/68
4798, 2-2 K.SVVTGGVQSVMGSR.L 2251.6 1 21/26
5104, 2-2 R.TLTAAAVSGAQPILSK.L 1704.1 1 21/30
5258, 1-2 R.TLTAAAVSGAQPILSK.L 1576.5 1 21/30
5404, 1 R.TLTAAAVSGAQPILSK.L 1839.2 1 22/30
5820, 2-2 K.DTVATQLSEAVDATR.G 2371.2 1 23/28
5992, 1-2 K.DTVATQLSEAVDATR.G 2439.5 1 23/28
5993, 1-2 K.SEEWADNHLPLTDAELAR.I 504.8 1 16/34
6040, 1 K.SEEWADNHLPLTDAELAR.I 1017.8 1 27/68
Page 75
7995, 1 R.RQVEDLQATFSSIHSFQDLSSSILAQSR.E
1169.4 1 33/108
62 NADH-cytochrome b5 reductase 3 isoform 2 31628.5
19379482
6
11 (11
0 0 0 0)
5336, 1-2 R.STPAITLESPDIK.Y 1004.2 1 16/24
5459, 1 R.STPAITLESPDIK.Y 1125.6 1 17/24
5874, 2-2 R.STPAITLESPDIKYPLR.L 1239.6 1 21/32
6078, 1-2 R.STPAITLESPDIKYPLR.L 809.9 1 16/32
6116, 1 R.STPAITLESPDIKYPLR.L 837.7 1 18/32
6266, 2-2 K.DILLRPELEELR.N 665.0 1 14/22
6434, 1-2 K.DILLRPELEELR.N 913.0 1 16/22
6896, 2-2 K.MSQYLESMQIGDTIEFR.G 1335.1 1 19/32
6909, 2-2 R.IDGNLVVRPYTPISSDDDKGFVDLVIK.V
986.3 1 34/104
7020, 1-2 R.APEAWDYGQGFVNEEMIR.D 1452.4 1 22/34
7144, 1-2 R.IDGNLVVRPYTPISSDDDKGFVDLVIK.V
689.7 1 30/104
63 bile salt sulfotransferase 33779.6 29540545
12 (12
0 0 0 0)
6233, 2-2 K.NHFTVAQAEDFDKLFQEK.M 939.3 1 29/68
6244, 2-2 K.NHFTVAQAEDFDKLFQEK.M 1991.2 1 21/34
6468, 1 K.NHFTVAQAEDFDKLFQEK.M 872.0 1 30/68
6472, 1 K.NHFTVAQAEDFDKLFQEK.M 3003.9 1 26/34
6586, 2-2 R.SPWVESEIGYTALSETESPR.L 1853.8 1 24/38
6778, 1-2 R.SPWVESEIGYTALSETESPR.L 1263.7 1 23/38
6782, 2-2 R.LFSSHLPIQLFPK.S 549.5 1 14/24
6791, 2-2 R.LFSSHLPIQLFPK.S 718.0 1 24/48
6899, 1 R.SPWVESEIGYTALSETESPR.L 2420.3 1 29/38
7641, 1-2 K.NFLLLSYEELK.Q 857.7 1 15/20
8210, 1 R.DVLVSGYFFWK.N 1098.7 1 15/20
9260, 1 K.SGTNWLAEILCLMHSK.G 1017.7 1 18/30
64 protein disulfide-isomerase precursor 57115.9 20070125
7 (7 0 0
0 0)
3976, 2-2 K.LGETYKDHENIVIAK.M 1815.4 1 30/56
5163, 1-2 K.VDATEESDLAQQYGVR.G 2109.8 1 21/30
5549, 2-2 K.YQLDKDGVVLFK.K 1082.2 1 16/22
5792, 1 K.YQLDKDGVVLFK.K 1282.2 1 17/22
6064, 2-2 K.THILLFLPK.S 1121.7 1 14/16
6616, 2-2 R.EADDIVNWLK.K 815.8 1 15/18
9945, 1 R.TGPAATTLPDGAAAESLVESSEVAVIGFFK.D
615.1 1 19/58
65 protein transport protein Sec23A 86160.3 38202214
7 (7 0 0
0 0)
4842, 1-2 K.ISGAIGPCVSLNSK.G 549.4 1 16/26
4974, 1-2 R.GAIQFVTQYQHSSGQR.R 1308.7 1 20/30
5991, 1 K.ERPDLPPIQYEPVLCSR.T 512.7 1 22/64
6983, 1-2 R.SSFLQVFNNSPDESSYYR.H 2192.4 1 25/34
7109, 1 R.SSFLQVFNNSPDESSYYR.H 544.5 1 15/34
8079, 2-2 R.MVVPVAALFTPLK.E 817.2 1 17/24
8745, 1 K.IDMNLTDLLGELQR.D 641.9 1 14/26
66 liver carboxylesterase 1 isoform c precursor 62392.5 68508957 12 (12
Page 76
0 0 0 0)
5115, 2-2 R.QKTEEELLETTLK.M 822.9 1 14/24
5259, 1-2 R.QKTEEELLETTLK.M 662.1 1 13/24
5271, 2-2 R.GNWGHLDQVAALR.W 1818.2 1 19/24
5529, 1 R.GNWGHLDQVAALR.W 1746.0 1 19/24
6400, 1-2 K.AGQLLSELFTNRK.E 841.9 1 16/24
7134, 2-2 K.LSEDCLYLNIYTPADLTK.K 1229.5 1 19/34
7368, 1-2 K.LSEDCLYLNIYTPADLTK.K 1027.3 1 18/34
7606, 1-2 R.LGIWGFFSTGDEHSR.G 975.8 1 16/28
7726, 1 R.LGIWGFFSTGDEHSR.G 972.4 1 18/28
9192, 2-2 R.ESQPLLGTVIDGMLLLK.T 884.5 1 21/32
9323, 1 R.ESQPLLGTVIDGMLLLK.T 549.9 1 17/32
9392, 1 R.ESQPLLGTVIDGMLLLK.T 591.8 1 16/32
67 ribosome-binding protein 1 108654.8
11061122
0
6 (6 0 0
0 0)
4046, 2-2 R.DALNQATSQVESK.Q 1156.8 1 17/24
4558, 1 K.LREAEETQSTLQAECDQYR.S 500.5 1 16/36
4866, 2-2 R.TLQEQLENGPNTQLAR.L 1124.0 1 18/30
5043, 1 K.SHVEDGDIAGAPASSPEAPPAEQDPVQLK.T
776.2 1 35/112
5376, 1 R.QLLLESQSQLDAAK.S 756.3 1 16/26
7551, 2-2 K.VEPAVSSVVNSIQVLTSK.A 544.3 1 18/34
68 apolipoprotein A-I preproprotein 30777.6 4557321
6 (6 0 0
0 0)
5488, 2-2 K.DSGRDYVSQFEGSALGK.Q 836.9 1 17/32
6087, 2-2 R.VKDLATVYVDVLK.D 1492.6 1 19/24
6100, 1 R.DYVSQFEGSALGK.Q 1614.7 1 19/24
6585, 2-2 K.LLDNWDSVTSTFSK.L 1095.1 1 18/26
6911, 2-2 K.DLATVYVDVLK.D 1218.5 1 17/20
7762, 2-2 K.VSFLSALEEYTK.K 1437.9 1 19/22
69 calnexin precursor 67567.8 10716563
10 (10
0 0 0 0)
5121, 1-2 K.TPELNLDQFHDK.T 1320.6 1 17/22
5621, 2-2 K.CGEDYKLHFIFR.H 1480.7 1 25/44
5792, 1-2 R.IVDDWANDGWGLKK.A 1508.7 1 19/26
6164, 2-2 R.GTLSGWILSK.A 1169.3 1 15/18
6332, 1-2 R.GTLSGWILSK.A 1191.6 1 15/18
6347, 1-2 R.GTLSGWILSK.A 1275.3 1 16/18
7382, 2-2 R.KIPNPDFFEDLEPFR.M 964.8 1 17/28
7396, 2-2 R.KIPNPDFFEDLEPFR.M 1677.7 1 29/56
7656, 1-2 R.KIPNPDFFEDLEPFR.M 776.8 1 16/28
7991, 2-2 K.IPNPDFFEDLEPFR.M 1032.2 1 17/26
70 vimentin 53651.3 62414289
9 (9 0 0
0 0)
4098, 1-2 K.FADLSEAANR.N 1037.1 1 16/18
4850, 2-2 R.LQDEIQNMKEEMAR.H 1026.2 2 16/26
5889, 2-2 K.ILLAELEQLKGQGK.S 609.2 1 17/26
6232, 2-2 R.KVESLQEEIAFLK.K 1490.6 1 17/24
6767, 2-2 K.ILLAELEQLK.G 1309.0 1 16/18
6976, 1-2 K.ILLAELEQLK.G 1160.9 1 16/18
7079, 1 K.ILLAELEQLK.G 1152.8 1 15/18
Page 77
8056, 1-2 R.ISLPLPNFSSLNLR.E 916.0 1 20/26
8163, 1 R.ISLPLPNFSSLNLR.E 900.2 1 19/26
71 D-3-phosphoglycerate dehydrogenase 56650.2 23308577
8 (8 0 0
0 0)
4476, 1-2 R.KILQDGGLQVVEK.Q 1238.9 1 17/24
4733, 2-2 K.ILQDGGLQVVEK.Q 545.4 1 15/22
5308, 1-2 K.VLISDSLDPCCR.K 622.7 1 16/22
6201, 1-2 K.TLGILGLGR.I 860.6 1 14/16
7476, 1-2 R.CGEEIAVQFVDMVK.G 1145.0 1 18/26
7718, 2-2 K.NAGNCLSPAVIVGLLK.E 1009.9 1 21/30
7972, 1-2 K.NAGNCLSPAVIVGLLK.E 944.6 1 20/30
7994, 1-2 K.NAGNCLSPAVIVGLLK.E 567.3 1 16/30
72 protein ERGIC-53 precursor 57548.6 5031873
9 (9 0 0
0 0)
4671, 2-2 R.YVSSLTEEISK.R 613.0 1 15/20
5211, 2-2 K.NNPAIVIIGNNGQIHYDHQNDGASQALASCQR.D
1819.0 1 41/124
5370, 1-2 K.NNPAIVIIGNNGQIHYDHQNDGASQALASCQR.D
1102.5 1 36/124
5403, 2-2 K.YQEEFEHFQQELDK.K 1641.2 1 20/26
5486, 1 K.NNPAIVIIGNNGQIHYDHQNDGASQALASCQR.D
1355.5 1 39/124
5548, 1-2 K.YQEEFEHFQQELDK.K 1863.4 1 20/26
6032, 2-2 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR.V
1061.0 1 35/108
6285, 1 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR.V
749.1 1 33/108
6292, 1-2 K.GHPDLQGQPAEEIFESVGDR.E 847.3 1 26/76
73 amine oxidase [flavin-containing] A 59681.3 4557735
9 (9 0 0
0 0)
4359, 2-2 K.IHFRPELPAER.N 594.1 1 14/20
4810, 2-2 R.NEHVDYVDVGGAYVGPTQNR.I 2466.3 1 26/38
4941, 1-2 R.NEHVDYVDVGGAYVGPTQNR.I 533.1 1 26/76
4949, 1-2 R.NEHVDYVDVGGAYVGPTQNR.I 2263.5 1 25/38
4962, 1-2 R.IFFAGTETATK.W 916.8 1 17/20
5117, 1 R.NEHVDYVDVGGAYVGPTQNR.I 2425.3 1 26/38
5759, 1 K.LNHPVTHVDQSSDNIIIETLNHEHYECK.Y
1439.5 1 36/108
6634, 2-2 K.DVPAVEITHTFWER.N 660.2 1 16/26
6698, 2-2 K.DVPAVEITHTFWER.N 687.4 1 18/26
74 tubulin beta-2C chain 49830.7 5174735
8 (8 0 0
0 0)
3852, 1-2 -.M*REIVHLQAGQCGNQIGAK.F 791.6 1 22/72
4022, 2-2 R.EIVHLQAGQCGNQIGAK.F 2424.0 1 25/32
4023, 2-2 R.EIVHLQAGQCGNQIGAK.F 2023.2 1 31/64
4104, 1-2 R.EIVHLQAGQCGNQIGAK.F 1975.4 1 30/64
4134, 1-2 R.EIVHLQAGQCGNQIGAK.F 1002.4 1 22/32
4305, 1-2 R.INVYYNEATGGK.Y 855.3 1 16/22
6567, 1 K.FWEVISDEHGIDPTGTYHGDSDLQLER.I
1045.1 1 35/104
Page 78
7094, 1-2 K.EAESCDCLQGFQLTHSLGGGTGSGMGTLLISK.I
1051.2 1 31/124
75 microsomal glutathione S-transferase 1 17598.6 9945306
11 (11
0 0 0 0)
4318, 2-2 R.KVFANPEDCVAFGKGENAK.K 1538.0 1 32/72
4329, 2-2 R.KVFANPEDCVAFGKGENAK.K 1159.4 1 21/36
4431, 1-2 R.KVFANPEDCVAFGKGENAK.K 2123.5 1 35/72
4700, 2-2 R.KVFANPEDCVAFGK.G 809.5 1 17/26
4820, 1-2 R.KVFANPEDCVAFGK.G 785.1 1 17/26
5193, 2-2 K.VFANPEDCVAFGK.G 884.5 1 18/24
5342, 1-2 K.VFANPEDCVAFGK.G 629.8 1 16/24
5487, 1 K.VFANPEDCVAFGK.G 1064.1 1 20/24
5690, 2-2 R.IYHTIAYLTPLPQPNR.A 2024.7 1 23/30
5823, 1-2 R.IYHTIAYLTPLPQPNR.A 2268.7 1 24/30
6705, 1-2 K.MMLMSTATAFYR.L 1208.5 1 17/22
76 tubulin beta chain 49670.5 29788785
7 (7 0 0
0 0)
4214, 2-2 R.ISVYYNEATGGK.Y 1126.2 1 17/22
4290, 1-2 R.ISVYYNEATGGK.Y 1279.9 1 19/22
6299, 2-2 K.FWEVISDEHGIDPTGTYHGDSDLQLDR.I
1248.1 1 33/104
7287, 1-2 R.ALTVPELTQQVFDAK.N 640.9 1 20/28
7709, 2-2 K.M*AVTFIGNSTAIQELFK.R 1144.4 1 21/32
8064, 2-2 K.MAVTFIGNSTAIQELFK.R 1384.2 1 22/32
8349, 1-2 K.MAVTFIGNSTAIQELFK.R 1308.9 1 21/32
77 complement C3 precursor 187146.3
11529867
8
5 (5 0 0
0 0)
4898, 1 K.LSINTHPSQKPLSITVR.T 904.6 1 26/64
5328, 1 K.VYAYYNLEESCTR.F 929.0 1 19/24
5910, 1 R.VPVAVQGEDTVQSLTQGDGVAK.L 609.7 1 23/42
6348, 1 R.LVAYYTLIGASGQR.E 1248.9 1 20/26
7696, 1 K.EYVLPSFEVIVEPTEK.F 973.1 1 21/30
78 sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 41900.0 8393516
10 (10
0 0 0 0)
3818, 2-2 K.GVNTVFHCASPPPSSNNK.E 518.3 1 18/34
3894, 1-2 K.GVNTVFHCASPPPSSNNK.E 688.8 1 19/34
5296, 1 R.VALAGTFHYYSCER.A 1293.5 1 19/26
5307, 1 R.VALAGTFHYYSCER.A 1374.2 1 18/26
6416, 1 R.FFLGDLCSR.Q 767.6 1 14/16
6983, 2-2 R.GYAVNVFDIQQGFDNPQVR.F 1697.4 1 22/36
7223, 1-2 R.GYAVNVFDIQQGFDNPQVR.F 2190.7 1 24/36
7340, 2-2 R.DPQLVPILIEAAR.N 810.6 1 20/24
7348, 1 R.GYAVNVFDIQQGFDNPQVR.F 1621.2 1 31/72
7575, 1-2 R.DPQLVPILIEAAR.N 745.5 1 19/24
79 dimethylaniline monooxygenase [N-oxide-forming] 5 isoform 1 60220.2
22131667
2
8 (8 0 0
0 0)
4160, 2-2 R.ALSQHPTLNDDLPNR.I 564.8 1 17/28
5711, 2-2 K.EFTETAAIFEDGSR.E 861.9 1 15/26
5760, 2-2 R.IAVIGGGVSGLSSIK.C 1159.0 1 21/28
6009, 1 R.IAVIGGGVSGLSSIK.C 1299.6 1 22/28
6317, 2-2 K.LALHLLLGPCTPIHYR.V 556.7 1 16/30
Page 79
6518, 1-2 K.LALHLLLGPCTPIHYR.V 2087.4 1 31/60
6525, 1 K.LALHLLLGPCTPIHYR.V 1706.5 1 29/60
6640, 2-2 R.VGDYGYPADVLFSSR.L 558.9 1 18/28
80 glycogen debranching enzyme isoform 1 174762.1
11673484
7
5 (5 0 0
0 0)
5500, 1 R.LEQGYELQFR.L 813.6 1 14/18
6316, 1 K.YTWNDVGQLVEK.L 682.0 1 15/22
6496, 1 K.WIQEHPECAYNLVNSPHLKPAWVLDR.A
1124.8 1 35/100
6993, 1 R.HGLIPNLLGEGIYAR.Y 642.0 1 19/28
7797, 1 K.LWEFFQVDVNK.A 1207.8 1 16/20
81 elongation factor 2 95337.6 4503483
10 (10
0 0 0 0)
4972, 2-2 R.ETVSEESNVLCLSK.S 1803.7 1 19/26
5104, 1-2 R.ETVSEESNVLCLSK.S 1516.5 1 19/26
7574, 1 R.KIWCFGPDGTGPNILTDITK.G 684.2 1 24/76
7583, 1 R.KIWCFGPDGTGPNILTDITK.G 712.8 1 18/38
7937, 2-2 R.TFCQLILDPIFK.V 701.7 1 14/22
8195, 1-2 R.TFCQLILDPIFK.V 1111.7 1 17/22
8315, 1 R.TFCQLILDPIFK.V 1340.6 1 18/22
8433, 1-2 R.ALLELQLEPEELYQTFQR.I 729.0 1 19/34
8553, 1 R.ALLELQLEPEELYQTFQR.I 519.9 1 16/34
8751, 1 R.YVEPIEDVPCGNIVGLVGVDQFLVK.T
1252.3 1 32/96
82 NAD(P) transhydrogenase, mitochondrial precursor 113894.8
12293915
5
5 (5 0 0
0 0)
4142, 2-2 K.AVVLAANHFGR.F 1480.0 1 17/20
4882, 1-2 K.QGFNVVVESGAGEASK.F 1049.1 1 20/30
5860, 2-2 R.EANSIIITPGYGLCAAK.A 975.0 1 20/32
6222, 1-2 K.ILIVGGGVAGLASAGAAK.S 1075.3 1 20/34
7694, 2-2 R.VTIAQGYDALSSMANIAGYK.A 1271.5 1 19/38
83 serum paraoxonase/arylesterase 1 precursor 39731.0 19923106
8 (8 0 0
0 0)
6519, 2-2 K.IFFYDSENPPASEVLR.I 1070.1 1 22/30
6628, 2-2 R.VVAEGFDFANGINISPDGK.Y 1598.7 1 21/36
6708, 1-2 K.YVYIAELLAHK.I 1382.0 1 17/20
6731, 1-2 K.IFFYDSENPPASEVLR.I 675.8 1 18/30
6796, 1-2 R.VVAEGFDFANGINISPDGK.Y 773.1 1 18/36
8045, 2-2 K.ILLMDLNEEDPTVLELGITGSK.F 519.7 1 15/42
8544, 2-2 K.GIETGSEDLEILPNGLAFISSGLK.Y 1429.7 1 32/92
8901, 1 K.GIETGSEDLEILPNGLAFISSGLK.Y 1606.9 1 31/92
84 cytochrome P450 2C8 isoform b 47785.8
31189330
9
8 (7 1 0
0 0)
4484, 2-2 R.VQEEAHCLVEELRK.T 1086.0 1 16/26
4492, 1-2 K.SVDDLKNLNTTAVTK.G 1479.9 1 21/28
4706, 2-2 K.EALIDNGEEFSGR.G 690.8 1 16/24
4830, 1-2 K.EALIDNGEEFSGR.G 802.2 1 17/24
6396, 2-2 K.DQNFLTLMK.R 639.1 2 13/16
6682, 2-2 K.EALIDNGEEFSGR.G 1146.5 2 18/24
6874, 1-2 K.EALIDNGEEFSGR.G 1020.7 1 18/24
Page 80
8810, 1 R.ILNSPWIQVCNNFPLLIDCFPGTHNK.V
603.2 1 25/100
85 coatomer subunit beta 107141.5 7705369
7 (6 1 0
0 0)
5934, 2-2 K.YEAAGTLVTLSSAPTAIK.A 1329.8 1 22/34
6093, 1-2 K.YEAAGTLVTLSSAPTAIK.A 610.8 1 18/34
6202, 1 R.SIFGEDALANVSIEKPIHQGPDAAVTGHIR.I
873.7 1 32/116
6436, 1-2 R.NAFMMLIHADQDR.A 520.6 1 14/24
6797, 2-2 K.TLQLALDLVSSR.N 1722.6 1 17/22
7088, 1-2 K.AAAQCYIDLIIK.E 783.2 1 13/22
7236, 1 K.AAAQCYIDLIIK.E 1134.0 4 16/22
86 voltage-dependent anion-selective channel protein 1 30772.3 4507879
9 (9 0 0
0 0)
4667, 2-2 K.LTFDSSFSPNTGKK.N 770.0 1 16/26
4788, 1-2 K.LTFDSSFSPNTGKK.N 622.3 1 15/26
5751, 2-2 K.VNNSSLIGLGYTQTLKPGIK.L 652.2 1 18/38
5962, 2-2 R.WTEYGLTFTEK.W 944.1 1 15/20
5984, 1 K.VNNSSLIGLGYTQTLKPGIK.L 534.0 1 17/38
6119, 1-2 R.WTEYGLTFTEK.W 739.8 1 13/20
6648, 2-2 K.LTLSALLDGK.N 869.5 1 15/18
6684, 1 K.WNTDNTLGTEITVEDQLAR.G 1170.4 1 21/36
6851, 1-2 K.LTLSALLDGK.N 938.2 1 14/18
87 villin-1 92694.4
19439423
7
7 (7 0 0
0 0)
4710, 1-2 K.LYHVSDSEGNLVVR.E 1249.1 1 20/26
5921, 1-2 K.LIIQWNGPESTR.M 762.3 1 16/22
6298, 1-2 R.DWSQITAEVTSPK.V 1318.8 1 18/24
6400, 1 R.DWSQITAEVTSPK.V 959.1 1 16/24
6639, 1-2 R.EVATRPLTQDLLSHEDCYILDQGGLK.I
755.4 1 26/100
7048, 1-2 R.ANFLNSNDVFVLK.T 1175.2 1 18/24
7175, 1 R.ANFLNSNDVFVLK.T 854.8 1 16/24
88 cytochrome P450 2C19 precursor 55944.8 4503219
10 (9 1
0 0 0)
4823, 2-2 R.MVVLHGYEVVK.E 1010.2 1 15/20
4947, 1-2 R.MVVLHGYEVVK.E 936.3 1 15/20
5348, 2-2 R.RFSLMTLR.N 1118.0 1 13/14
5487, 1-2 R.RFSLMTLR.N 1148.9 1 13/14
5913, 2-2 K.RFDYKDQQFLNLMEK.L 1320.0 1 24/56
6011, 2-2 K.DQQFLNLMEK.L 1079.8 1 13/18
6670, 2-2 K.EALIDLGEEFSGR.G 953.9 1 17/24
6682, 2-2 K.EALIDLGEEFSGR.G 1146.5 2 18/24
6874, 1-2 K.EALIDLGEEFSGR.G 1020.7 1 18/24
6995, 1 K.EALIDLGEEFSGR.G 852.8 1 18/24
89 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 1
precursor 69283.5 35493916
9 (9 0 0
0 0)
5354, 2-2 R.YHVPVVVVPEGSASDTHEQAILR.L 643.4 1 33/88
6285, 1-2 R.LQVTNVLSQPLTQATVK.L 882.9 1 19/32
6363, 1 R.LQVTNVLSQPLTQATVK.L 550.4 1 17/32
Page 81
7360, 2-2 R.LSKEETVLATVQALQTASHLSQQADLR.S
907.1 1 29/104
7674, 2-2 K.NPILWNVADVVIK.F 860.1 1 16/24
8050, 1 K.NPILWNVADVVIK.F 1069.3 1 19/24
8793, 1-2 R.SIVEEIEDLVAR.L 550.5 1 17/22
8829, 1-2 R.SIVEEIEDLVAR.L 724.4 2 14/22
8865, 1 R.SIVEEIEDLVAR.L 1416.2 1 17/22
90 non-specific lipid-transfer protein isoform 1 proprotein 58993.3 19923233
7 (7 0 0
0 0)
3566, 1-2 K.KLEEEGEQFVKK.I 1078.1 1 26/44
3910, 2-2 K.KLEEEGEQFVK.K 1362.9 1 16/20
3975, 1-2 K.KLEEEGEQFVK.K 1268.7 1 16/20
6600, 1 K.GHPLGATGLAQCAELCWQLR.G 776.6 1 22/38
7947, 1-2 R.QLIQGGVAECVLALGFEK.M 734.0 1 16/34
8063, 1 R.QLIQGGVAECVLALGFEK.M 1258.1 1 20/34
8613, 1-2 K.ADCTITMADSDFLALMTGK.M 810.6 1 17/36
91 ATP-binding cassette sub-family D member 3 isoform a 75475.5 4506341
7 (7 0 0
0 0)
5612, 2-2 R.IANPDQLLTQDVEK.F 1192.6 1 19/26
5619, 2-2 K.VGITLFTVSHR.K 640.5 2 15/20
6124, 2-2 K.EYLDNVQLGHILER.E 897.8 1 17/26
8087, 2-2 R.VLGELWPLFGGR.L 649.5 1 14/22
8354, 1-2 R.VLGELWPLFGGR.L 663.2 1 15/22
8470, 1 R.VLGELWPLFGGR.L 1048.7 1 18/22
8930, 1-2 R.EGGWDSVQDWMDVLSGGEK.Q 808.1 1 17/36
92 long-chain-fatty-acid--CoA ligase 3 80419.6 42794752
7 (6 0 1
0 0)
5375, 2-2 R.LLLCGGAPLSATTQR.F 893.0 1 20/28
5667, 1 R.LLLCGGAPLSATTQR.F 542.9 4 15/28
6634, 1-2 K.GIIVHTMAAVEALGAK.A 756.6 1 15/30
7258, 1 R.NLFILAYNYK.M 1810.7 1 16/18
7408, 2-2 K.VLSEAAISASLEKFEIPVK.I 539.8 3 16/36
7592, 1 R.LSPEPWTPETGLVTDAFK.L 694.0 1 21/34
7769, 1 K.VLSEAAISASLEKFEIPVK.I 842.8 1 18/36
93 PREDICTED: liver carboxylesterase 1-like 27540.5
34191633
5
7 (7 0 0
0 0)
5236, 1 R.NGNPNGEGLPHWPEYNQK.E 517.3 1 15/34
5352, 1-2 R.NFHTVPYMVGINK.Q 876.5 1 18/24
6984, 2-2 K.LKDKEVAFWTNLFAK.K 1570.9 1 19/28
7274, 1 K.LKDKEVAFWTNLFAK.K 1143.1 1 26/56
7864, 2-2 K.EVAFWTNLFAK.K 782.7 1 16/20
8151, 2-2 K.TVIGDHGDELFSVFGAPFLK.E 1133.1 1 18/38
8223, 1 K.EVAFWTNLFAK.K 837.7 1 16/20
94 glutamate dehydrogenase 2, mitochondrial precursor 61433.6 31377775
6 (6 0 0
0 0)
4148, 1-2 R.YSTDVSVDEVK.A 1022.5 1 16/20
5303, 1-2 K.CAVVDVPFGGAK.A 735.2 3 14/22
5741, 1-2 K.YNLGLDLR.T 1269.7 1 13/14
6153, 1 R.DDGSWEVIEGYR.A 1696.9 1 18/22
6284, 1-2 K.CIAVGESDGSIWNPDGIDPK.E 555.5 2 16/38
6357, 1 K.CIAVGESDGSIWNPDGIDPK.E 1595.3 1 26/38
Page 82
95 cytochrome P450 2D6 isoform 1 55730.1 40805836
6 (6 0 0
0 0)
5583, 1-2 R.VQQEIDDVIGQVR.R 1562.5 1 18/24
6270, 1-2 K.AVSNVIASLTCGR.R 1371.7 1 18/24
6952, 1-2 R.LLDLAQEGLKEESGFLR.E 546.3 1 16/32
8078, 1-2 K.AFLTQLDELLTEHR.M 1245.5 1 17/26
8082, 1-2 K.AFLTQLDELLTEHR.M 637.1 1 13/26
8274, 1 K.GTTLITNLSSVLKDEAVWEKPFR.F 715.2 1 28/88
96 17-beta-hydroxysteroid dehydrogenase type 6 35965.5 19743808
9 (9 0 0
0 0)
4898, 2-2 R.GQTSDRLETVTLDVTK.M 950.6 1 19/30
4914, 2-2 R.GQTSDRLETVTLDVTK.M 873.5 1 18/30
5030, 1-2 R.GQTSDRLETVTLDVTK.M 621.2 1 16/30
5877, 2-2 R.IVNVSSILGR.V 1250.5 1 16/18
6008, 1-2 K.ISIVEPGYFR.T 1092.8 1 16/18
6032, 1-2 R.IVNVSSILGR.V 1303.6 1 16/18
6089, 1 K.ISIVEPGYFR.T 1105.3 1 16/18
7798, 2-2 K.EGLLNCSTNLNLVTDCMEHALTSVHPR.T
1287.1 1 31/104
8637, 1-2 K.ETYGQQYFDALYNIMK.E 707.9 1 16/30
97 desmoplakin isoform I 331771.4 58530840
5 (5 0 0
0 0)
6304, 1-2 K.ITNLTQQLEQASIVK.K 1325.5 1 18/28
7098, 1 K.TIADLELHYQEFIR.N 540.0 1 15/26
7272, 1-2 K.SVEEVASEIQPFLR.G 519.0 1 13/26
7473, 2-2 R.GYFNEELSEILSDPSDDTK.G 509.4 1 13/36
7668, 1-2 R.TLELQGLINDLQR.E 703.1 1 15/24
98 trifunctional enzyme subunit beta, mitochondrial precursor 51294.1 4504327
6 (6 0 0
0 0)
4383, 2-2 R.LAAAFAVSR.L 1073.1 1 14/16
4709, 1-2 R.AALTGLLHR.T 936.1 1 14/16
5472, 2-2 K.DQLLLGPTYATPK.V 921.4 1 16/24
6129, 2-2 K.FNNWGGSLSLGHPFGATGCR.L 754.4 1 29/76
6300, 1-2 K.FNNWGGSLSLGHPFGATGCR.L 793.2 1 27/76
8562, 1 K.EVVDYIIFGTVIQEVK.T 650.4 1 17/30
99 general vesicular transport factor p115 107906.7 4505541
5 (5 0 0
0 0)
3508, 2-2 K.TLEQHDNIVTHYK.N 569.5 1 14/24
6659, 1 R.DSEQVAELKQELATLK.S 1202.7 1 21/30
6688, 1-2 K.VTNLHLMLQLVR.V 1249.9 1 17/22
7301, 2-2 R.QSEDLGSQFTEIFIK.Q 544.3 1 14/28
7482, 1 K.EQDDLLVLLADQDQK.I 781.1 1 17/28
100 ATP-dependent RNA helicase DDX3X isoform 2 73156.0
30117146
7
5 (5 0 0
0 0)
5186, 2-2 K.SPILVATAVAAR.G 1348.4 1 18/22
6047, 2-2 R.LEQELFSGGNTGINFEK.Y 667.8 1 18/32
6848, 2-2 R.VGNLGLATSFFNER.N 1081.9 1 18/26
6906, 2-2 K.HVINFDLPSDIEEYVHR.I 952.8 1 24/64
8495, 1 R.SFLLDLLNATGK.D 2175.9 1 19/22
101 serum paraoxonase/lactonase 3 39607.2 29788996
5 (5 0 0
0 0)
Page 83
4384, 2-2 K.GFCSANGITVSADQK.Y 832.3 1 16/28
4410, 1-2 K.YVYVADVAAK.N 741.0 1 11/18
5820, 1-2 K.LLNYNPEDPPGSEVLR.I 698.2 1 20/30
6245, 2-2 K.IFLMDLNEQNPR.A 1632.2 1 17/22
7068, 1-2 K.SVNDIVVLGPEQFYATR.D 512.2 1 17/32
102 cytochrome P450 3A7 57525.2
26229093
2
6 (6 0 0
0 0)
4698, 2-2 R.VLQNFSFKPCK.E 779.0 1 15/20
6684, 2-2 K.DNIDPYIYTPFGSGPR.N 889.1 1 17/30
6900, 1-2 K.DNIDPYIYTPFGSGPR.N 898.5 1 16/30
7148, 2-2 K.LKEMVPIIAQYGDVLVR.N 686.6 1 18/32
7751, 1-2 K.EMVPIIAQYGDVLVR.N 513.4 1 16/28
7768, 2-2 R.VDFLQLMIDSQNSK.D 1584.7 1 19/26
103 synaptic vesicle membrane protein VAT-1 homolog 41920.0 18379349
9 (9 0 0
0 0)
4787, 2-2 R.PAAPPAPGPGQLTLR.L 514.1 1 17/28
4796, 2-2 R.TVENVTVFGTASASK.H 935.8 1 18/28
4913, 1-2 R.TVENVTVFGTASASK.H 1016.6 1 18/28
5986, 2-2 R.CLVLTGFGGYDK.V 951.3 4 15/22
6142, 1-2 R.CLVLTGFGGYDK.V 799.3 3 14/22
6334, 2-2 K.VVTYGMANLLTGPK.R 1097.9 1 17/26
6538, 1-2 K.VVTYGMANLLTGPK.R 923.5 1 15/26
6750, 2-2 R.ACGLNFADLMAR.Q 1389.0 1 18/22
6956, 1-2 R.ACGLNFADLMAR.Q 1163.8 1 16/22
104 delta(24)-sterol reductase precursor 60100.9 13375618
6 (6 0 0
0 0)
5326, 1-2 K.LGCQDAFPEVYDK.I 1029.3 1 17/24
5696, 2-2 R.EGLEYIPLR.H 749.9 1 14/16
6363, 2-2 R.PGWLTVSLR.V 1020.1 1 14/16
6803, 2-2 K.LNSIGNYYKPWFFK.H 882.1 1 16/26
7023, 1-2 K.LNSIGNYYKPWFFK.H 663.0 1 14/26
7470, 2-2 R.YLFGWMVPPK.I 673.7 1 13/18
105 17-beta-hydroxysteroid dehydrogenase 13 isoform A 33655.2
21003211
0
8 (7 1 0
0 0)
4100, 1 R.KLGVTAHAYVVDCSNR.E 2044.2 1 30/60
4256, 1-2 K.LGVTAHAYVVDCSNR.E 1279.1 1 19/28
4469, 1 K.LGVTAHAYVVDCSNR.E 795.8 1 15/28
4906, 1 K.LGVTAHAYVVDCSNREEIYR.S 516.3 1 16/38
6003, 2-2 K.RQSILVLWDINKR.G 1624.9 1 28/48
6012, 2-2 K.RQSILVLWDINKR.G 785.2 1 17/24
6870, 1-2 R.QSILVLWDINKR.G 693.0 1 15/22
6956, 1 R.QSILVLWDINKR.G 990.6 1 18/22
106 histone H4 11367.3 4504301
6 (5 1 0
0 0)
4018, 2-2 R.DNIQGITKPAIR.R 738.3 1 15/22
4820, 2-2 R.ISGLIYEETR.G 1216.0 1 17/18
4916, 1-2 R.ISGLIYEETR.G 1214.7 1 17/18
6135, 2-2 R.KTVTAMDVVYALK.R 768.4 1 15/24
6294, 2-2 K.TVTAMDVVYALKR.Q 840.4 1 14/24
7005, 1-2 K.TVTAMDVVYALK.R 1260.1 1 19/22
107 UDP-glucuronosyltransferase 2B4 precursor 60512.1
14994450
9
7 (5 2 0
0 0)
Page 84
4703, 1-2 K.TVINDPLYKENAMK.L 569.6 1 16/26
5768, 2-2 K.FEVYPVSLTK.T 739.3 1 13/18
6202, 2-2 K.ADIWLIR.N 765.6 1 11/12
6224, 2-2 K.TILDELVQR.G 897.4 1 15/16
6398, 1-2 K.TILDELVQR.G 919.7 1 15/16
6485, 2-2 R.ANVIASALAKIPQK.V 650.7 1 15/26
6681, 1-2 R.ANVIASALAKIPQK.V 856.5 1 17/26
108 alcohol dehydrogenase 1B 39835.3 34577061
9 (9 0 0
0 0)
4258, 2-2 K.AKELGATECINPQDYK.K 1042.3 1 18/30
4355, 1-2 K.AKELGATECINPQDYK.K 980.4 1 21/30
6378, 1 K.VCLIGCGFSTGYGSAVNVAK.V 2888.7 1 30/38
7599, 2-2 K.VTPGSTCAVFGLGGVGLSAVMGCK.A
1578.3 1 28/46
7612, 2-2 K.VTPGSTCAVFGLGGVGLSAVMGCK.A
1144.2 1 28/46
7853, 1-2 K.VTPGSTCAVFGLGGVGLSAVMGCK.A
938.3 1 27/46
7869, 1-2 K.VTPGSTCAVFGLGGVGLSAVMGCK.A
2082.2 1 31/46
7989, 1 K.VTPGSTCAVFGLGGVGLSAVMGCK.A
1042.9 1 25/46
8272, 1 K.KFSLDALITHVLPFEK.I 1452.1 1 30/60
109 calpain-1 catalytic subunit 81889.4 12408656
4 (4 0 0
0 0)
6178, 1-2 R.LEICNLTPDALK.S 1106.7 3 15/22
6188, 1-2 R.KAPSDLYQIILK.A 806.4 1 15/22
6896, 1-2 R.NYPATFWVNPQFK.I 879.4 1 16/24
7271, 1 R.FRLPPGEYVVVPSTFEPNKEGDFVLR.F
1819.4 1 35/100
110 actin, cytoplasmic 1 41736.5 4501885
6 (6 0 0
0 0)
5248, 2-2 R.VAPEEHPVLLTEAPLNPK.A 615.9 1 18/34
6269, 1-2 K.DLYANTVLSGGTTM*YPGIADR.M 1620.0 1 23/40
6443, 2-2 R.TTGIVM*DSGDGVTHTVPIYEGYALPHAILR.L
1203.5 1 35/116
6652, 1-2 R.TTGIVM*DSGDGVTHTVPIYEGYALPHAILR.L
1079.4 1 33/116
6738, 1 R.TTGIVM*DSGDGVTHTVPIYEGYALPHAILR.L
1177.7 1 37/116
6924, 1-2 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L
1739.5 1 39/116
111 cytochrome P450 4A11 59347.5
15893724
2
4 (4 0 0
0 0)
3676, 2-2 K.CAFSHQGSIQVDR.N 1400.3 1 28/48
5348, 1 R.NAFHQNDTIYSLTSAGR.W 972.6 1 21/32
7449, 1 K.ALQQFPCPPSHWLFGHIQELQQDQELQR.I
586.2 1 33/108
8686, 1-2 R.NSQSYIQAISDLNNLVFSR.V 1083.3 1 22/36
112 sorbitol dehydrogenase 38324.3
15662757
1
5 (5 0 0
0 0)
Page 85
5360, 1-2 R.MHSVGICGSDVHYWEYGR.I 926.7 1 20/34
6153, 2-2 K.AMGAAQVVVTDLSATR.L 1275.9 1 21/30
6340, 1-2 K.AMGAAQVVVTDLSATR.L 526.7 1 16/30
7625, 1 K.LPDNVTFEEGALIEPLSVGIHACR.R 1304.7 1 34/92
8793, 1 K.VLVCGAGPIGMVTLLVAK.A 509.2 1 15/34
113 perilipin-1 55990.0
22371820
3
9 (9 0 0
0 0)
5255, 2-2 R.LASGGADLALGSIEK.V 2064.4 1 22/28
5374, 1 R.LSTQFTAANELACR.G 1647.5 1 19/26
5402, 1-2 R.LASGGADLALGSIEK.V 2205.5 1 21/28
5534, 1 R.LASGGADLALGSIEK.V 1885.8 1 21/28
6747, 2-2 K.GLTLLDGDLPEQENVLQR.V 509.6 1 18/34
6963, 1-2 K.GLTLLDGDLPEQENVLQR.V 716.9 1 21/34
6972, 2-2 K.VLGAALAGCELAWGVAR.D 2072.2 1 23/32
7173, 1-2 K.VLGAALAGCELAWGVAR.D 1845.5 1 23/32
7280, 1 K.VLGAALAGCELAWGVAR.D 2265.0 1 24/32
114 myosin-Ib isoform 2 124949.7 44889481
6 (6 0 0
0 0)
4902, 1-2 K.AAHIFNEALVCHQIR.Y 1409.8 1 20/28
5357, 1-2 K.VSTTLNVAQAYYAR.D 563.9 1 15/26
7245, 2-2 R.IFLLTNNNLLLADQK.S 1443.9 1 18/28
7461, 1 R.NFYELSPHIFALSDEAYR.S 837.1 1 21/34
7486, 1-2 R.IFLLTNNNLLLADQK.S 1941.1 1 20/28
7487, 1-2 R.IFLLTNNNLLLADQK.S 1877.6 1 20/28
115 catenin alpha-1 100070.6 55770844
4 (4 0 0
0 0)
4271, 1-2 K.IAEQVASFQEEK.S 730.6 1 15/22
6581, 1-2 K.LIEVANLACSISNNEEGVK.L 1011.3 1 18/36
7370, 2-2 R.LLILADMADVYK.L 2181.7 1 20/22
9833, 1 R.VLTDAVDDITSIDDFLAVSENHILEDVNK.C
1047.3 1 32/112
116 elongation factor 1-alpha 2 50469.8 4503475
8 (8 0 0
0 0)
4442, 2-2 K.IGGIGTVPVGR.V 1159.3 1 18/20
4666, 2-2 K.THINIVVIGHVDSGK.S 994.7 1 16/28
4794, 1-2 K.THINIVVIGHVDSGK.S 1071.2 1 20/28
4956, 1 K.THINIVVIGHVDSGK.S 2255.0 1 31/56
4970, 1 K.THINIVVIGHVDSGK.S 1278.6 1 20/28
5672, 1-2 R.EHALLAYTLGVK.Q 1415.3 1 18/22
5769, 1 R.EHALLAYTLGVK.Q 1002.9 1 16/22
9434, 2-2 K.NMITGTSQADCAVLIVAAGVGEFEAGISK.N
1553.3 1 37/112
117 hemoglobin subunit delta 16055.4 4504351
5 (5 0 0
0 0)
3989, 1-2 K.VVAGVANALAHK.Y 1474.7 1 19/22
4244, 2-2 K.VVAGVANALAHKYH.- 1299.3 1 18/26
4331, 1-2 K.VVAGVANALAHKYH.- 1953.4 1 21/26
4661, 1-2 K.VNVDAVGGEALGR.L 1429.0 1 20/24
6716, 1 K.VLGAFSDGLAHLDNLK.G 1598.9 1 21/30
118 prohibitin-2 isoform 1 33296.1
22130758
4
7 (7 0 0
0 0)
5298, 1-2 K.FNASQLITQR.A 1535.3 1 17/18
Page 86
5888, 2-2 K.LLLGAGAVAYGVR.E 2237.8 1 21/24
6131, 1 K.LLLGAGAVAYGVR.E 1882.6 1 19/24
6333, 2-2 R.IGGVQQDTILAEGLHFR.I 1225.1 1 28/64
6345, 2-2 R.IGGVQQDTILAEGLHFR.I 745.6 1 16/32
6531, 1-2 R.IGGVQQDTILAEGLHFR.I 1741.2 1 32/64
8079, 1 R.IYLTADNLVLNLQDESFTR.G 1003.9 1 20/36
119 alpha-mannosidase 2 131139.6 51477714
4 (4 0 0
0 0)
4926, 2-2 K.NKVEDSGIFTIK.N 685.0 1 14/22
5530, 2-2 R.LLAENNEIISNIR.D 1540.1 1 20/24
5806, 1 K.ILESASSNSHLADYVLYK.N 1214.3 1 22/34
7304, 1 K.FLSSSLYTALTEAR.R 1078.4 1 17/26
120 junction plakoglobin 81744.3 12056468
5 (5 0 0
0 0)
4563, 2-2 R.AGDKDDITEPAVCALR.H 814.2 1 17/30
5835, 1 R.NLALCPANHAPLQEAAVIPR.L 973.2 1 27/76
6216, 1-2 R.LVQNCLWTLR.N 705.7 4 13/18
8896, 1 K.TLVTQNSGVEALIHAILR.A 1203.2 1 20/34
8897, 1 K.TLVTQNSGVEALIHAILR.A 667.0 1 32/68
121 adipocyte plasma membrane-associated protein 46480.1 24308201
5 (5 0 0
0 0)
3411, 2-2 R.RPLRPQVVTDDDGQAPEAK.D 1269.3 1 29/72
4370, 2-2 K.LENGEIETIAR.F 898.3 1 16/20
4433, 2-2 R.LLEYDTVTR.E 835.9 1 15/16
4467, 1-2 K.LENGEIETIAR.F 1417.2 1 17/20
6552, 1-2 K.EPPLLLGVLHPNTK.L 718.1 1 16/26
122 cathepsin D preproprotein 44552.0 4503143
5 (5 0 0
0 0)
5604, 2-2 K.FDGILGM*AYPR.I 1167.8 1 17/20
6538, 2-2 K.FDGILGMAYPR.I 1228.9 1 17/20
7030, 1-2 K.AIGAVPLIQGEYMIPCEK.V 983.1 1 21/34
7037, 1-2 K.AIGAVPLIQGEYMIPCEK.V 1247.6 1 23/34
8013, 1-2 K.LVDQNIFSFYLSR.D 1103.3 1 18/24
123 UDP-glucuronosyltransferase 2B15 precursor 61036.0
11651729
9
5 (5 0 0
0 0)
4464, 2-2 K.GAALSVDIR.T 925.1 1 14/16
5330, 2-2 K.SSAIKLEVYPTSLTK.N 1248.7 1 19/28
5480, 1-2 K.SSAIKLEVYPTSLTK.N 1449.3 1 21/28
7162, 2-2 K.VLVWPTEYSHWINMK.T 571.5 1 16/28
8579, 1 R.TYWDFEFPRPFLPNVDFVGGLHCK.P
963.9 1 30/92
124 redox-regulatory protein PAMM isoform 1 precursor 25764.0
34492582
8
5 (5 0 0
0 0)
4984, 2-2 R.TEVKDFQPYFK.G 1060.0 1 15/20
7529, 2-2 K.VNLLSVLEAAK.M 860.5 1 16/20
7684, 2-2 K.SMLDQLGVPLYAVVK.E 939.5 1 20/28
7817, 2-2 R.LGVWYNFFR.A 583.3 1 13/16
7948, 1-2 K.SMLDQLGVPLYAVVK.E 525.1 2 13/28
125 retinol dehydrogenase 16 35673.2
15024722
6
5 (5 0 0
0 0)
5007, 1-2 K.VAM*IEPGYFK.T 834.5 1 14/18
5114, 2-2 K.TESVAAAAQWVK.E 1196.3 1 16/22
Page 87
5337, 2-2 R.DKYVFITGCDSGFGK.L 1410.8 1 19/28
5351, 2-2 R.DKYVFITGCDSGFGK.L 2907.7 1 32/56
7875, 2-2 R.DKGLWGLVNNAGISLPTAPNELLTK.Q
593.8 1 32/96
126 retinol dehydrogenase 10 38087.3 25282469
5 (5 0 0
0 0)
5397, 1-2 K.FGVVGFHESLSHELK.A 1392.8 1 19/28
6509, 2-2 R.LFALEFAR.R 746.2 1 13/14
6788, 1 R.LFALEFAR.R 722.2 1 13/14
7251, 1 K.EVGEVSVLVNNAGVVSGHHLLECPDELIER.T
755.2 1 32/116
7967, 2-2 K.SILPFEAVVCMYR.F 997.3 1 17/24
127 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
precursor 50701.3 20070197
6 (6 0 0
0 0)
5729, 2-2 K.NTLLIAGLQAR.N 1830.4 1 19/20
5770, 2-2 R.YSQTGNYELAVALSR.W 621.3 1 15/28
5853, 1-2 K.NTLLIAGLQAR.N 1849.3 1 18/20
6621, 2-2 R.TLVLLDNLNVR.E 1021.7 1 15/20
6932, 1 R.TLVLLDNLNVR.E 1120.0 1 16/20
7160, 2-2 K.LPDVYGVFQFK.V 937.0 1 15/20
128 betaine--homocysteine S-methyltransferase 1 44998.2
15726633
7
4 (4 0 0
0 0)
4928, 1 K.ISGQEVNEAACDIAR.Q 1099.8 1 20/28
5289, 1 K.AGPWTPEAAVEHPEAVR.Q 695.0 1 18/32
5877, 1 R.QVADEGDALVAGGVSQTPSYLSCK.S
605.3 1 30/92
6442, 1 K.AGASIIGVNCHFDPTISLK.T 577.6 1 14/36
129 cytochrome b5 isoform 1 15330.0 41281768
5 (5 0 0
0 0)
4137, 1-2 R.EQAGGDATENFEDVGHSTDAR.E 682.7 1 18/40
4425, 2-2 K.STWLILHHK.V 811.6 2 12/16
4526, 1-2 K.FLEEHPGGEEVLR.E 548.9 1 17/24
4979, 2-2 K.TFIIGELHPDDRPK.L 717.9 1 14/26
5103, 1-2 K.TFIIGELHPDDRPK.L 1665.3 1 20/26
130 eukaryotic initiation factor 4A-II 46402.0 83700235
5 (5 0 0
0 0)
4569, 1-2 K.LQAEAPHIVVGTPGR.V 1104.8 1 20/28
6086, 2-2 R.VLITTDLLAR.G 1282.8 1 17/18
6246, 1-2 R.VLITTDLLAR.G 1193.8 1 15/18
6671, 1-2 R.GFKDQIYEIFQK.L 1390.2 1 16/22
7574, 1-2 K.MFVLDEADEMLSR.G 2422.9 1 21/24
131 apoptosis-inducing factor 1, mitochondrial isoform 2 precursor 66294.3 22202629
5 (5 0 0
0 0)
5946, 2-2 K.ELWFSDDPNVTK.T 1004.7 1 15/22
6840, 2-2 R.ALGTEVIQLFPEK.G 635.9 2 13/24
7062, 1-2 R.ALGTEVIQLFPEK.G 1169.1 1 18/24
7091, 1-2 R.SNIWVAGDAACFYDIK.L 754.6 1 18/30
8855, 1-2 K.SITIIGGGFLGSELACALGR.K 545.2 1 16/38
132 arylacetamide deacetylase 45733.4 68299767
4 (4 0 0
0 0)
3612, 2-2 K.GHVYNNPNYGSSELAK.K 1508.7 1 22/30
Page 88
6208, 2-2 R.FWSEYFTTDR.S 942.5 1 16/18
7149, 2-2 R.LINQYIEWLK.E 1173.8 1 16/18
7901, 2-2 R.IGISGDSAGGNLAAAVTQQLLDDPDVK.I
700.7 1 20/52
133 myosin-Ic isoform c 117906.3
12449424
0
4 (4 0 0
0 0)
5922, 2-2 K.GDVVLQSDHVIETLTK.T 678.5 1 14/30
6065, 1-2 K.TLFATEDALEVR.R 734.8 1 16/22
6701, 2-2 R.LLQSNPVLEAFGNAK.T 856.5 1 17/28
9264, 1 K.MSLLQLVEILQSK.E 1201.0 1 17/24
134 prenylcysteine oxidase 1 precursor 56639.8
16679530
1
4 (4 0 0
0 0)
6434, 2-2 K.FLNEMIAPVMR.V 1112.2 1 15/20
6812, 2-2 K.IAIIGAGIGGTSAAYYLR.Q 1530.5 1 23/34
7199, 2-2 R.SDFYDIVLVATPLNRK.M 819.5 1 14/30
8146, 1 R.SDFYDIVLVATPLNR.K 782.9 1 16/28
135 coatomer subunit gamma 97717.7 11559929
5 (4 1 0
0 0)
5838, 1-2 R.ALQQYTLEPSEKPFDLK.S 1016.5 1 20/32
6136, 2-2 K.SSPEPVALTESETEYVIR.C 1058.7 1 20/34
6658, 2-2 R.ALCQITDSTMLQAIER.Y 650.0 1 14/30
6894, 1-2 R.ALCQITDSTMLQAIER.Y 944.1 1 16/30
7001, 1-2 R.QEIFQEQLAAVPEFR.G 693.0 1 16/28
136 cytochrome P450 2A6 precursor 56517.1
18933923
3
4 (4 0 0
0 0)
4707, 2-2 K.GYGVVFSNGER.A 1110.9 1 16/20
6070, 2-2 K.DKEFLSLLR.M 1072.7 1 15/16
6375, 2-2 R.FDYKDKEFLSLLR.M 1033.1 1 18/24
7691, 2-2 R.TVSNVISSIVFGDRFDYK.D 944.8 1 20/34
137 cytoplasmic dynein 1 heavy chain 1 532406.6 33350932
4 (4 0 0
0 0)
4344, 1-2 R.FTQDTQPHYIYSPR.E 531.1 1 18/26
6810, 1-2 R.QALVAIFTHLR.K 717.9 1 14/20
6964, 2-2 K.LNTQEIFDDWAR.K 551.4 1 12/22
7112, 2-2 R.MLSAVSQQVQCIQEALR.E 812.4 1 15/32
138 annexin A4 36084.8 4502105
4 (4 0 0
0 0)
4476, 2-2 K.GLGTDDNTLIR.V 884.7 1 14/20
4698, 1-2 R.NHLLHVFDEYKR.I 777.2 1 15/22
7295, 1-2 K.GAGTDEGCLIEILASR.T 514.3 1 16/30
7954, 1-2 K.GLGTDEDAIISVLAYR.N 1092.7 1 18/30
139 dynamin-1-like protein isoform 1 81876.7
17146091
4
4 (4 0 0
0 0)
5808, 2-2 R.RPLILQLVHVSQEDK.R 573.5 1 13/28
6120, 1-2 K.GHAVNLLDVPVPVAR.K 1104.5 1 18/28
6255, 2-2 K.ALQGASQIIAEIR.E 986.8 1 16/24
8616, 1-2 K.LHDAIVEVVTCLLR.K 1386.5 1 17/26
140 cytochrome P450 3A5 isoform 1 57108.3 4503231
6 (6 0 0
0 0)
5944, 2-2 K.DVEINGVFIPK.G 1073.5 1 15/20
6112, 1-2 K.DVEINGVFIPK.G 1059.0 1 15/20
6802, 2-2 K.DSIDPYIYTPFGTGPR.N 909.8 1 17/30
Page 89
7029, 1-2 K.DSIDPYIYTPFGTGPR.N 601.4 1 14/30
8316, 1-2 K.EMFPIIAQYGDVLVR.N 559.8 1 13/28
8848, 1-2 R.LGIPGPTPLPLLGNVLSYR.Q 575.7 1 19/36
141 ADP/ATP translocase 2 32852.0
15607145
9
4 (4 0 0
0 0)
4361, 1-2 K.QIFLGGVDKR.T 748.6 1 15/18
5552, 1-2 R.AAYFGIYDTAK.G 805.3 1 16/20
6342, 1-2 K.DFLAGGVAAAISK.T 712.0 1 19/24
6772, 1-2 K.EQGVLSFWR.G 628.8 1 13/16
142 protein transport protein Sec24A isoform 1 119748.6
11617478
0
9 (8 1 0
0 0)
5182, 1 R.VDNLSDEGALNISDR.T 991.5 1 18/28
6935, 1-2 K.TLETQSALGPALQAAFK.L 552.7 2 15/32
7822, 2-2 R.TYINPFVSFLDQR.R 889.0 1 17/24
8073, 2-2 R.TYINPFVSFLDQR.R 1003.9 1 17/24
8075, 1-2 R.TYINPFVSFLDQR.R 866.1 1 17/24
8309, 1-2 R.TYINPFVSFLDQR.R 1082.9 1 17/24
8440, 1 R.TYINPFVSFLDQR.R 1443.2 1 21/24
8898, 1-2 R.DALVNAVIDSLSAYR.S 1556.6 1 19/28
8970, 1 R.DALVNAVIDSLSAYR.S 1514.7 1 19/28
143 fructose-bisphosphate aldolase B 39472.8 40354205
5 (5 0 0
0 0)
5408, 1-2 R.IADQCPSSLAIQENANALAR.Y 2193.5 1 26/38
5518, 1 R.IADQCPSSLAIQENANALAR.Y 2314.1 1 26/38
5524, 1 R.IADQCPSSLAIQENANALAR.Y 2355.2 1 28/38
6392, 1 K.KYTPEQVAMATVTALHR.T 1520.8 1 31/64
6786, 1 R.YASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEK.V
993.1 1 36/136
144 peroxisomal multifunctional enzyme type 2 isoform 2 79685.9 4504505
4 (4 0 0
0 0)
4874, 1-2 R.VVLVTGAGAGLGR.A 2007.9 1 21/24
5171, 2-2 R.AYALAFAER.G 1053.4 1 13/16
6321, 2-2 R.GALVVVNDLGGDFK.G 1861.1 1 20/26
6509, 1-2 R.GALVVVNDLGGDFK.G 2024.8 1 21/26
145 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor 68569.0 4506675
5 (5 0 0
0 0)
6935, 1-2 K.VACITEQVLTLVNKR.I 737.6 1 15/28
7118, 2-2 K.ISVIVETVYTHVLHPYPTQITQSEK.Q 805.3 1 29/96
7377, 1-2 K.ISVIVETVYTHVLHPYPTQITQSEK.Q 709.9 1 27/96
7754, 2-2 R.ATSFLLALEPELEAR.L 1026.8 1 20/28
8025, 1-2 R.ATSFLLALEPELEAR.L 722.6 1 17/28
146 aldehyde oxidase 147916.9 71773480
3 (3 0 0
0 0)
7132, 2-2 K.TGIIAAVTAFAANK.H 1346.0 1 19/26
8244, 1 R.GFGFPQAALITESCITEVAAK.C 1032.1 1 22/40
9219, 1 K.VFCVGQLVCAVLADSEVQAK.R 1203.1 1 22/38
147 membrane-associated progesterone receptor component 1 21671.0 5729875
4 (4 0 0
0 0)
4251, 1-2 R.GDQPAASGDSDDDEPPPLPR.L 794.4 1 20/38
5561, 2-2 R.KFYGPEGPYGVFAGR.D 1708.5 1 22/28
5716, 1-2 R.KFYGPEGPYGVFAGR.D 1540.3 1 20/28
Page 90
6312, 1-2 K.FYGPEGPYGVFAGR.D 1256.1 1 21/26
148 tripeptidyl-peptidase 1 preproprotein 61247.6 5729770
4 (4 0 0
0 0)
4599, 2-2 R.LFGGNFAHQASVAR.V 1499.9 1 20/26
6108, 1-2 R.ILSGRPPLGFLNPR.L 808.6 1 18/26
6129, 1 R.ILSGRPPLGFLNPR.L 530.7 1 16/26
9308, 1 R.VPIPWVSGTSASTPVFGGILSLINEHR.I
2364.2 1 38/104
149 exportin-1 123385.0 4507943
3 (3 0 0
0 0)
4450, 2-2 K.NVDILKDPETVK.Q 530.2 1 14/22
6174, 2-2 K.EFAGEDTSDLFLEER.E 728.7 1 17/28
8603, 1 K.LDINLLDNVVNCLYHGEGAQQR.M 859.4 1 30/84
150 hydroxymethylglutaryl-CoA synthase, mitochondrial isoform 1 precursor 56635.1 5031751
4 (4 0 0
0 0)
5933, 2-2 R.PTGGAGAVAMLIGPK.A 1939.0 1 22/28
8752, 1 K.QAGSDRPFTLDDLQYMIFHTPFCK.M
779.1 1 25/92
8867, 1-2 R.IGAFSYGSGLAASFFSFR.V 539.3 1 14/34
8924, 1 R.IGAFSYGSGLAASFFSFR.V 1146.0 1 20/34
151 AP-2 complex subunit beta isoform b 104551.9 4557469
5 (5 0 0
0 0)
4284, 1-2 R.LSHANSAVVLSAVK.V 1018.7 1 18/26
7437, 2-2 R.LASQANIAQVLAELK.E 1625.2 1 21/28
7678, 1-2 R.LASQANIAQVLAELK.E 1390.3 1 21/28
7816, 1 R.LASQANIAQVLAELK.E 1513.8 1 21/28
8648, 1 K.KPSETQELVQQVLSLATQDSDNPDLR.D
1344.8 1 34/100
152 aldehyde dehydrogenase, mitochondrial isoform 1 precursor 56380.9 25777732
4 (4 0 0
0 0)
6218, 1-2 R.ANNSTYGLAAAVFTK.D 656.7 1 15/28
7191, 1-2 R.TFVQEDIYDEFVER.S 1136.7 1 17/26
8124, 1-2 K.VAEQTPLTALYVANLIK.E 994.7 1 23/32
8230, 1 K.VAEQTPLTALYVANLIK.E 704.6 1 19/32
153 hemoglobin subunit alpha 15257.4 4504345
6 (6 0 0
0 0)
3932, 1-2 K.VGAHAGEYGAEALER.M 1170.6 1 21/28
3938, 1-2 K.VGAHAGEYGAEALER.M 1134.4 2 26/56
6010, 1-2 K.FLASVSTVLTSK.Y 1218.5 1 17/22
6068, 1 K.FLASVSTVLTSK.Y 1272.6 1 18/22
7570, 1-2 K.VADALTNAVAHVDDMPNALSALSDLHAHK.L
999.9 1 27/112
7692, 1 K.VADALTNAVAHVDDMPNALSALSDLHAHK.L
1160.6 1 32/112
154 cytochrome P450 1A2 58407.1 73915100
4 (4 0 0
0 0)
4594, 2-2 R.FLTADGTAINKPLSEK.M 2206.7 1 24/30
4882, 2-2 R.YGDVLQIR.I 968.5 1 13/14
5306, 2-2 R.IGSTPVLVLSR.L 965.8 1 17/20
5456, 1-2 R.IGSTPVLVLSR.L 800.7 1 16/20
155 reticulon-4 isoform A 129930.3 24431935 5 (5 0 0
Page 91
0 0)
3902, 2-2 K.YSNSALGHVNCTIK.E 1498.4 1 21/26
4443, 2-2 R.HQAQIDHYLGLANK.N 1757.6 1 20/26
4565, 1-2 R.HQAQIDHYLGLANK.N 1265.9 1 17/26
6753, 1-2 R.AYLESEVAISEELVQK.Y 851.6 1 16/30
6896, 1 R.AYLESEVAISEELVQK.Y 630.8 1 20/30
156 carnitine O-palmitoyltransferase 2, mitochondrial precursor 73776.6 4503023
3 (3 0 0
0 0)
4481, 2-2 K.ELHEQLVALDK.Q 935.7 1 15/20
8255, 1 K.YILSDSSPAPEFPLAYLTSENR.D 734.0 1 21/42
9484, 1 K.LSPDAVAQLAFQMAFLR.Q 1361.3 1 18/32
157 myosin-10 228996.6 41406064
3 (3 0 0
0 0)
7192, 1-2 R.QLLQANPILESFGNAK.T 828.1 1 17/30
7251, 1-2 K.VVSSVLQFGNISFK.K 937.7 1 17/26
7370, 1 K.LQQLFNHTMFILEQEEYQR.E 1511.6 1 30/72
158 AP-2 complex subunit alpha-1 isoform 2 105360.8 19913416
3 (3 0 0
0 0)
4733, 1-2 R.VLQIVTNRDDVQGYAAK.T 691.3 1 18/32
6899, 1-2 R.GLAVFISDIR.N 1447.9 1 16/18
8210, 1-2 K.VGGYILGEFGNLIAGDPR.S 1275.5 1 20/34
159 heterogeneous nuclear ribonucleoprotein K isoform a 51027.9 14165437
4 (4 0 0
0 0)
5915, 1-2 R.LLIHQSLAGGIIGVK.G 664.0 1 16/28
5973, 1 R.LLIHQSLAGGIIGVK.G 1255.5 1 18/28
7392, 1-2 K.IILDLISESPIK.G 1391.9 1 16/22
7978, 1 K.IDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVK.Q
768.0 1 32/132
160 ras-related protein Rab-14 23896.8 19923483
5 (5 0 0
0 0)
4895, 2-2 K.IYQNIQDGSLDLNAAESGVQHKPSAPQGGR.L
988.4 1 32/116
5040, 1-2 K.IYQNIQDGSLDLNAAESGVQHKPSAPQGGR.L
1216.2 1 38/116
5194, 1 K.IYQNIQDGSLDLNAAESGVQHKPSAPQGGR.L
926.8 1 34/116
6232, 1-2 K.TGENVEDAFLEAAK.K 677.6 1 16/26
6752, 1-2 R.NLTNPNTVIILIGNK.A 685.6 1 17/28
161 prohibitin 29803.9 4505773
3 (3 0 0
0 0)
5032, 2-2 R.IFTSIGEDYDER.V 627.7 1 14/22
7895, 1-2 K.AAELIANSLATAGDGLIELR.K 1113.5 1 21/38
8658, 1 R.AATFGLILDDVSLTHLTFGK.E 762.2 1 19/38
162 estradiol 17-beta-dehydrogenase 12 34323.9 7705855
5 (5 0 0
0 0)
6512, 1-2 R.TIAVDFASEDIYDKIK.T 1060.8 1 18/30
7361, 2-2 K.TFVDFFSQCLHEEYR.S 1223.0 1 18/28
7707, 2-2 K.GVFVQSVLPYFVATK.L 509.6 1 16/28
7710, 2-2 K.GVFVQSVLPYFVATK.L 532.6 1 18/28
7744, 1 K.TFVDFFSQCLHEEYR.S 1384.1 1 19/28
163 hemoglobin subunit beta 15998.3 4504349
5 (4 1 0
0 0)
Page 92
5931, 1-2 K.GTFATLSELHCDKLHVDPENFR.L 561.4 1 26/84
6893, 2-2 R.FFESFGDLSTPDAVMGNPK.V 874.9 1 20/36
6910, 2-2 R.FFESFGDLSTPDAVMGNPK.V 521.0 1 16/36
7109, 1-2 R.FFESFGDLSTPDAVMGNPK.V 1089.7 1 22/36
8160, 1-2 R.LLGNVLVCVLAHHFGK.E 699.0 1 15/30
164 glutamate dehydrogenase 1, mitochondrial precursor 61397.5 4885281
4 (4 0 0
0 0)
5601, 1 K.HGGTIPIVPTAEFQDR.I 537.4 1 18/30
5858, 1-2 R.GASIVEDKLVEDLR.T 1377.4 1 19/26
6611, 1-2 K.AKPYEGSILEADCDILIPAASEK.Q 504.5 1 19/44
6690, 1 K.AKPYEGSILEADCDILIPAASEK.Q 818.2 1 22/44
165 SEC14-like protein 2 isoform 1 46145.0 7110715
7 (7 0 0
0 0)
4166, 2-2 K.INYGGDIPR.K 719.6 1 13/16
4245, 1-2 K.INYGGDIPR.K 687.0 1 13/16
4785, 2-2 R.FDNTYSFIHAK.K 1325.1 1 17/20
4904, 1-2 R.FDNTYSFIHAK.K 1219.8 1 16/20
4906, 1-2 R.FDNTYSFIHAK.K 1258.1 1 17/20
8738, 1-2 K.LFPVAYNLIKPFLSEDTR.K 515.4 1 15/34
8829, 1 K.LFPVAYNLIKPFLSEDTR.K 701.8 1 19/34
166 40S ribosomal protein SA 32853.8 59859885
4 (4 0 0
0 0)
3965, 2-2 K.FAAATGATPIAGR.F 1490.5 1 20/24
4040, 1-2 K.FAAATGATPIAGR.F 1712.7 1 21/24
4936, 1-2 R.YVDIAIPCNNK.G 764.8 1 13/20
6944, 2-2 R.ADHQPLTEASYVNLPTIALCNTDSPLR.Y
675.7 1 28/104
167 guanine nucleotide-binding protein subunit beta-2-like 1 35076.5 5174447
5 (5 0 0
0 0)
4978, 1 K.YTVQDESHSEWVSCVR.F 588.1 1 15/30
5658, 2-2 K.IIVDELKQEVISTSSK.A 1049.8 1 20/30
5850, 2-2 R.FSPNSSNPIIVSCGWDK.L 723.3 1 17/32
6014, 1-2 R.FSPNSSNPIIVSCGWDK.L 678.3 1 18/32
6095, 1 R.FSPNSSNPIIVSCGWDK.L 539.6 1 16/32
168 carbamoyl-phosphate synthase [ammonia], mitochondrial isoform a precursor 165648.8
16979091
5
4 (3 1 0
0 0)
5537, 1 R.GAEVHLVPWNHDFTK.M 1549.2 1 27/56
6148, 2-2 K.VSGLLVLDYSK.D 1638.6 1 18/20
6316, 1-2 K.VSGLLVLDYSK.D 692.8 4 15/20
7912, 1 K.MEYDGILIAGGPGNPALAEPLIQNVR.K
1146.7 1 23/50
169 60S ribosomal protein L4 47697.0 16579885
4 (4 0 0
0 0)
5220, 1-2 R.KLDELYGTWR.K 912.7 1 13/18
5908, 2-2 K.APIRPDIVNFVHTNLR.K 943.3 1 24/60
6069, 1-2 K.APIRPDIVNFVHTNLR.K 802.5 1 23/60
6906, 1-2 R.FCIWTESAFR.K 1359.1 1 16/18
170 sodium/potassium-transporting ATPase subunit alpha-1 isoform c 112999.5
23768110
9
3 (3 0 0
0 0)
3272, 1-2 K.VDNSSLTGESEPQTR.S 687.5 1 17/28
5021, 2-2 R.SPDFTNENPLETR.N 1417.0 2 18/24
Page 93
6140, 1-2 K.GVGIISEGNETVEDIAAR.L 586.0 1 16/34
171 cytochrome b-c1 complex subunit 2, mitochondrial precursor 48442.7 50592988
3 (3 0 0
0 0)
3827, 2-2 K.TIAQGNLSNTDVQAAK.N 1678.5 1 23/30
5649, 1 R.NALANPLYCPDYR.I 752.6 1 17/24
6111, 1 R.MALIGLGVSHPVLK.Q 1069.1 2 17/26
172 phosphoglucomutase-1 isoform 1 61448.7 21361621
5 (4 1 0
0 0)
4168, 2-2 R.YDYEEVEAEGANK.M 1664.7 1 18/24
4259, 1-2 R.YDYEEVEAEGANK.M 1939.5 1 19/24
4791, 1-2 R.LYIDSYEKDVAK.I 1620.1 1 18/22
5187, 1 K.FNISNGGPAPEAITDK.I 1028.8 2 19/30
5265, 1 K.FNISNGGPAPEAITDK.I 969.1 1 21/30
173 corticosteroid 11-beta-dehydrogenase isozyme 1 32400.8 5031765
6 (6 0 0
0 0)
3870, 2-2 K.AVSGIVHMQAAPK.E 1148.4 1 17/24
3926, 1-2 K.AVSGIVHMQAAPK.E 1367.5 1 18/24
7234, 1-2 K.FALDGFFSSIRK.E 1138.9 1 17/22
7761, 2-2 K.FALDGFFSSIR.K 1363.9 1 17/20
8028, 1-2 K.FALDGFFSSIR.K 1267.7 1 17/20
8133, 1 K.FALDGFFSSIR.K 1342.3 1 17/20
174 translational activator GCN1 292707.0 54607053
4 (3 1 0
0 0)
6430, 2-2 R.LLTWVIGTGSPR.L 782.1 1 14/22
8619, 1-2 K.VLPLEALVTDAGEVTEAGK.A 756.0 1 17/36
9338, 1 K.AALLETLSLLLAK.V 1077.3 2 16/24
9471, 1-2 K.AALLETLSLLLAK.V 1285.2 1 17/24
175 phosphate carrier protein, mitochondrial isoform b precursor 39958.5 47132595
3 (3 0 0
0 0)
3951, 2-2 R.IQTQPGYANTLR.D 576.3 1 15/22
7115, 2-2 K.VLYSNMLGEENTYLWR.T 717.5 1 17/30
7757, 1-2 K.GWAPTFLGYSMQGLCK.F 835.5 1 18/30
176 transitional endoplasmic reticulum ATPase 89321.3 6005942
4 (4 0 0
0 0)
5374, 2-2 R.LGDVISIQPCPDVK.Y 538.4 3 14/26
5574, 1 K.AIANECQANFISIK.G 652.8 1 17/26
7319, 1-2 R.LDQLIYIPLPDEK.S 696.4 1 14/24
7460, 1 R.LDQLIYIPLPDEK.S 976.7 1 16/24
177 carnitine O-palmitoyltransferase 1, liver isoform isoform 1 88367.1 73623030
3 (3 0 0
0 0)
4745, 2-2 K.GDINPNIPYPTR.L 839.2 1 17/22
5439, 2-2 R.LAALTAGDRVPWAR.C 615.0 2 13/26
5542, 2-2 R.AGNAIHAILLYR.R 1065.9 1 17/22
178 exportin-2 110415.8 29029559
3 (3 0 0
0 0)
7710, 1 R.GSNTIASAAADKIPGLLGVFQK.L 705.4 1 19/42
8081, 1-2 K.LLQTDDEEEAGLLELLK.S 1059.5 1 18/32
8392, 1 K.YGALALQEIFDGIQPK.M 1111.7 1 19/30
179 cytosolic 10-formyltetrahydrofolate dehydrogenase 98828.6 21614513
3 (3 0 0
0 0)
5870, 1 K.GVVNVLPGSGSLVGQR.L 515.2 1 17/30
Page 94
6069, 1 R.LFVEDSIHDEFVR.R 796.0 1 14/24
6470, 1 K.VLEVEDSTDFFK.S 2127.5 1 20/22
180 filamin-B isoform 2 278160.3
10599051
4
4 (4 0 0
0 0)
5660, 1-2 R.IGNLQTDLSDGLR.L 684.4 1 14/24
5730, 1-2 R.GAGIGGLGITVEGPSESK.I 546.5 2 15/34
5842, 1 R.GAGIGGLGITVEGPSESK.I 619.6 1 19/34
8393, 1 R.LIALLEVLSQK.R 1061.8 1 17/20
181 microsomal triglyceride transfer protein large subunit precursor 99350.6
15328540
8
4 (4 0 0
0 0)
5830, 1 K.LTYSTEVLLDR.G 994.9 1 16/20
7659, 1-2 R.NFLAFIQHLR.T 1266.8 1 15/18
7748, 1 R.NFLAFIQHLR.T 1138.6 1 15/18
7761, 1 R.SASTYSLDILYSGSGILR.R 626.2 1 15/34
182 abhydrolase domain-containing protein 14B 22345.5 14249382
4 (4 0 0
0 0)
5450, 1-2 R.AVAIDLPGLGHSK.E 1019.6 1 18/24
6179, 2-2 R.FSVLLLHGIR.F 1053.6 1 15/18
6328, 2-2 R.EGTIQVQGQALFFR.E 661.8 1 13/26
6345, 1-2 R.FSVLLLHGIR.F 1122.6 1 15/18
183 cytochrome P450 2C18 isoform 1 precursor 55710.4 13699816
5 (5 0 0
0 0)
3627, 2-2 R.SIEDRVQEEAR.C 1040.6 1 15/20
3692, 1-2 R.SIEDRVQEEAR.C 938.2 1 14/20
7458, 2-2 R.YGLLLLLK.Y 981.9 1 12/14
7586, 2-2 R.DFIDCFLIK.M 1089.7 2 13/16
7695, 1-2 R.YGLLLLLK.Y 971.3 1 12/14
184 tricarboxylate transport protein, mitochondrial precursor 34012.4 21389315
3 (3 0 0
0 0)
5372, 1-2 K.GTYQGLTATVLK.Q 921.9 1 16/22
6867, 1-2 R.GLSSLLYGSIPK.A 1466.7 1 16/22
7618, 1-2 R.FGMFEFLSNHMR.D 626.8 1 13/22
185 alcohol dehydrogenase 1C 39867.4 4501933
6 (2 4 0
0 0)
5554, 1 K.KPFSIEEVEVAPPK.A 692.9 1 17/26
6240, 2-2 K.VCLIGCGFSTGYGSAVKVAK.V 1868.7 2 23/38
6257, 2-2 K.VCLIGCGFSTGYGSAVKVAK.V 2332.0 2 26/38
6440, 1-2 K.VCLIGCGFSTGYGSAVKVAK.V 2270.9 2 25/38
6648, 1 K.VCLIGCGFSTGYGSAVKVAK.V 941.5 2 20/38
9056, 1 K.KFSLDALITNILPFEK.I 2453.3 1 26/30
186 histone H2B type 1-C/E/F/G/I 13906.0 4504271
7 (5 2 0
0 0)
7892, 2-2 K.AM*GIMNSFVNDIFER.I 1667.2 1 21/28
7892, 2-2 K.AMGIM*NSFVNDIFER.I 968.5 2 17/28
8168, 1-2 K.AM*GIMNSFVNDIFER.I 1813.1 1 21/28
8168, 1-2 K.AMGIM*NSFVNDIFER.I 1203.8 2 18/28
8330, 2-2 K.AMGIMNSFVNDIFER.I 1041.3 1 18/28
8590, 1-2 K.AMGIMNSFVNDIFER.I 1790.4 1 21/28
8612, 1-2 K.AMGIMNSFVNDIFER.I 1424.1 1 20/28
187 ras-related protein Rab-7a 23489.6 34147513
5 (4 1 0
0 0)
Page 95
6190, 2-2 R.LVTMQIWDTAGQER.F 1783.1 1 22/26
6358, 1-2 R.LVTMQIWDTAGQER.F 1287.7 1 19/26
6891, 2-2 K.EAINVEQAFQTIAR.N 1027.2 1 17/26
7097, 1-2 K.EAINVEQAFQTIAR.N 1073.8 1 18/26
7268, 1-2 R.DPENFPFVVLGNK.I 593.5 1 14/24
188 UDP-glucuronosyltransferase 2A2 60771.7
33360924
5
4 (2 2 0
0 0)
6921, 2-2 K.ANLIASALAQIPQK.V 560.1 1 16/26
7161, 1-2 K.ANLIASALAQIPQK.V 1619.8 1 21/26
8092, 1-2 R.AVFWIEFVM*R.H 1003.9 1 13/18
9034, 1 R.AVFWIEFVMR.H 1206.7 1 14/18
189 cytochrome P450 4F11 precursor 60145.5
19308317
8
6 (4 2 0
0 0)
7316, 1-2 R.SPLAFIPFSAGPR.N 833.0 1 18/24
7424, 1 R.SPLAFIPFSAGPR.N 611.8 1 16/24
7511, 2-2 K.VVLALTLLHFR.I 807.8 2 15/20
7758, 1-2 K.VVLALTLLHFR.I 1175.1 2 16/20
7962, 2-2 K.TLDFIDVLLLSKDEDGK.E 980.5 1 17/32
8214, 1-2 K.TLDFIDVLLLSKDEDGK.E 794.9 1 16/32
190 vitronectin precursor 54305.3 88853069
3 (2 1 0
0 0)
5304, 2-2 R.FEDGVLDPDYPR.N 939.8 2 15/22
6969, 2-2 R.SIAQYWLGCPAPGHL.- 838.6 1 15/28
7644, 2-2 R.DVWGIEGPIDAAFTR.I 1000.0 1 18/28
191 voltage-dependent anion-selective channel protein 3 isoform 2 30789.6
20887946
5
5 (3 2 0
0 0)
4974, 2-2 K.VCNYGLTFTQK.W 1301.6 1 17/20
5112, 1-2 K.VCNYGLTFTQK.W 1100.5 1 16/20
5937, 1-2 K.VNNASLIGLGYTQTLRPGVK.L 1217.1 1 22/38
6648, 2-2 K.LTLSALIDGK.N 869.5 1 15/18
6851, 1-2 K.LTLSALIDGK.N 938.2 1 14/18
192 cytochrome P450 2A13 56687.2 13699809
4 (3 1 0
0 0)
4622, 2-2 R.RFSIATLR.G 1056.3 1 13/14
6375, 2-2 R.FDYEDKEFLSLLR.M 1033.1 1 18/24
7784, 2-2 R.DFIDSFLIR.M 946.5 2 13/16
8036, 1-2 R.DFIDSFLIR.M 837.1 2 13/16
193 UDP-glucuronosyltransferase 2B28 isoform 2 precursor 38743.0
33303381
1
3 (2 0 1
0 0)
4901, 2-2 K.LEVYPTSLTK.T 636.2 1 14/18
6453, 1 K.KWDQFYSEVLGR.P 518.4 1 15/22
7161, 1-2 R.ANVIATALAKIPQK.I 760.4 2 16/26
194 calcium-binding mitochondrial carrier protein Aralar1 74761.4 21361103
4 (3 0 0
1 0)
5182, 1-2 R.AGQTTYSGVIDCFRK.I 1150.5 1 19/28
6707, 2-2 R.YEGFFGLYR.G 909.7 1 15/16
6916, 1-2 R.YEGFFGLYR.G 821.2 1 15/16
7438, 1-2 R.DIPFSAIYFPVYAHCK.L 528.8 2 14/30
195 enoyl-CoA hydratase, mitochondrial precursor 31387.2
19409732
3
4 (4 0 0
0 0)
8642, 1-2 K.ALNALCDGLIDELNQALK.T 692.1 1 16/34
Page 96
8732, 1 K.ALNALCDGLIDELNQALK.T 1585.1 1 23/34
8736, 1 K.ALNALCDGLIDELNQALK.T 2049.9 1 25/34
9158, 1 K.ICPVETLVEEAIQCAEK.I 695.8 1 15/32
196 rab GDP dissociation inhibitor alpha 50582.4 4503971
2 (2 0 0
0 0)
5724, 2-2 R.FQLLEGPPESM*GRGR.D 537.8 1 15/28
8709, 1 R.KFDLGQDVIDFTGHALALYR.T 2649.8 1 37/76
197 protein disulfide-isomerase A3 precursor 56782.0 21361657
2 (2 0 0
0 0)
7407, 1-2 R.ELSDFISYLQR.E 535.3 1 14/20
8486, 1 K.FISDKDASIVGFFDDSFSEAHSEFLK.A
2906.1 1 40/100
198 glyceraldehyde-3-phosphate dehydrogenase 36053.0 7669492
2 (2 0 0
0 0)
5349, 1-2 R.GALQNIIPASTGAAK.A 597.0 1 16/28
8776, 1 K.VIHDNFGIVEGLMTTVHAITATQK.T 1098.5 1 32/92
199 alcohol dehydrogenase [NADP+] 36572.8 24497577
2 (2 0 0
0 0)
5979, 1 R.HIDCAAIYGNEPEIGEALKEDVGPGK.A
1445.3 1 36/100
8346, 1 R.AWRDPDEPVLLEEPVVLALAEK.Y 2061.6 1 37/84
200 apolipoprotein E precursor 36153.8 4557325
2 (2 0 0
0 0)
3680, 2-2 K.VQAAVGTSAAPVPSDNH.- 567.8 1 16/32
5044, 2-2 K.AYKSELEEQLTPVAEETR.A 1918.0 1 25/34
201 mitochondrial carrier homolog 2 33330.7 7657347
4 (4 0 0
0 0)
3621, 2-2 K.VLQHYQESDKGEELGPGNVQK.E 2162.8 1 36/80
3711, 1-2 K.VLQHYQESDKGEELGPGNVQK.E 1185.3 1 29/80
6030, 2-2 R.SAATLITHPFHVITLR.S 1366.4 1 30/60
6198, 1-2 R.SAATLITHPFHVITLR.S 554.6 1 18/30
202 fibrinogen gamma chain isoform gamma-A precursor 49496.2 70906437
2 (2 0 0
0 0)
4868, 1 K.VAQLEAQCQEPCKDTVQIHDITGK.D
828.9 1 28/92
5500, 2-2 K.QSGLYFIKPLK.A 631.9 2 13/20
203 UBX domain-containing protein 4 56777.2 24307965
2 (2 0 0
0 0)
4107, 1 K.SDTATGGESAGHATSSQEPSGCSDQRPAEDLNIR.V
829.0 1 32/132
7821, 2-2 -.MLWFQGAIPAAIATAK.R 516.0 1 13/30
204 ATP-binding cassette sub-family A member 6 184284.2 27436953
2 (2 0 0
0 0)
5978, 2-2 K.LPVADVYPLSQTFHK.L 753.7 1 17/28
6401, 2-2 R.TATALTTSILDEKPVIIASCLHK.E 852.6 1 27/88
205 histone H2A type 1-D 14107.4 10800130
4 (4 0 0
0 0)
5084, 2-2 R.AGLQFPVGR.V 805.1 1 14/16
5222, 1-2 R.AGLQFPVGR.V 830.3 1 14/16
7737, 2-2 K.VTIAQGGVLPNIQAVLLPK.K 954.7 1 23/36
8151, 1 K.VTIAQGGVLPNIQAVLLPK.K 1282.0 1 31/72
206 estradiol 17-beta-dehydrogenase 2 42784.9 4504503 4 (4 0 0
Page 97
0 0)
4784, 2-2 K.AVLVTGGDCGLGHALCK.Y 1767.0 1 24/32
4925, 1-2 K.AVLVTGGDCGLGHALCK.Y 1355.2 1 21/32
8430, 1-2 R.NFLLLINSLASK.D 2724.9 1 20/22
8501, 1 R.NFLLLINSLASK.D 2493.5 1 19/22
207 dehydrogenase/reductase SDR family member on chromosome X precursor 36442.9
19380485
0
2 (2 0 0
0 0)
5092, 1 R.VAIVTGGTDGIGYSTAK.H 1588.9 1 22/32
9356, 1 R.VYAVGAAVILAQLLR.R 1594.3 1 19/28
208 UDP-glucuronosyltransferase 1-7 precursor 59818.5 41282213
3 (3 0 0
0 0)
8937, 1-2 K.GAGVTLNVLEM*TSEDLENALK.A 1168.7 1 21/40
9215, 1 K.GAGVTLNVLEMTSEDLENALK.A 738.1 1 26/80
9242, 1-2 K.GAGVTLNVLEMTSEDLENALK.A 1275.3 1 21/40
209 7-dehydrocholesterol reductase 54489.1
11994311
2
4 (4 0 0
0 0)
6123, 2-2 K.FLPGYVGGIQEGAVTPAGVVNK.Y 1022.6 1 24/42
6302, 1-2 K.FLPGYVGGIQEGAVTPAGVVNK.Y 895.3 1 22/42
6940, 2-2 K.LLVSGFWGVAR.H 955.1 1 15/20
7169, 1-2 K.LLVSGFWGVAR.H 1045.1 1 16/20
210 protein-glutamine gamma-glutamyltransferase 2 isoform a 77328.4 39777597
2 (2 0 0
0 0)
7864, 1 K.YLLNLNLEPFSEK.S 1565.3 1 19/24
8128, 1 R.ALLVEPVINSYLLAER.D 1060.4 1 23/30
211 phosphatidylinositol-binding clathrin assembly protein isoform 1 70754.1 56788366
2 (2 0 0
0 0)
7936, 1-2 R.ATTLSNAVSSLASTGLSLTK.V 1562.4 1 23/38
8130, 1 R.NTLFNLSNFLDK.S 736.0 1 15/22
212 2,4-dienoyl-CoA reductase, mitochondrial precursor 36067.5 4503301
2 (2 0 0
0 0)
5715, 1 K.VAGHPNIVINNAAGNFISPTER.L 724.6 1 26/84
7196, 2-2 K.EQWDTIEELIR.K 889.4 1 14/20
213 SEC14-like protein 3 46047.9 27923592
2 (2 0 0
0 0)
7072, 1 R.GSSHQVEYEILFPGCVLR.W 1469.1 1 23/34
8226, 1-2 K.FRENVQDVLPALPNPDDYFLLR.W 951.1 1 32/84
214 UDP-glucuronosyltransferase 1-4 precursor 60024.7 6005930
4 (4 0 0
0 0)
5282, 2-2 R.CCVELLHNEALIR.H 1522.7 1 21/24
5430, 1-2 R.CCVELLHNEALIR.H 1619.6 1 21/24
5561, 1 R.CCVELLHNEALIR.H 1002.0 1 17/24
7587, 2-2 K.FFTLTAYAVPWTQK.E 727.6 1 19/26
215 acetyl-CoA acetyltransferase, mitochondrial precursor 45199.3 4557237
3 (3 0 0
0 0)
6178, 1 R.QAVLGAGLPISTPCTTINK.V 797.0 1 21/36
8478, 2-2 R.TPIGSFLGSLSLLPATK.L 819.3 1 17/32
8840, 1 R.TPIGSFLGSLSLLPATK.L 1249.1 1 21/32
216 surfeit locus protein 4 30393.8 19557691
5 (5 0 0
0 0)
8039, 2-2 R.LCLISTFLEDGIR.M 1757.8 1 21/24
8303, 1-2 R.LCLISTFLEDGIR.M 1024.5 1 16/24
Page 98
8322, 1-2 R.LCLISTFLEDGIR.M 1694.7 1 20/24
8411, 1 R.LCLISTFLEDGIR.M 1697.0 1 20/24
9398, 1-2 R.NLALGGGLLLLLAESR.S 1689.6 1 21/30
217 arginase-1 isoform 2 34734.7 10947139
2 (2 0 0
0 0)
7122, 1-2 K.TGLLSGLDIM*EVNPSLGK.T 800.0 1 17/34
7490, 1 K.RPIHLSFDVDGLDPSFTPATGTPVVGGLTYR.E
833.7 1 32/120
218 T-complex protein 1 subunit zeta isoform a 58023.9 4502643
2 (2 0 0
0 0)
5010, 1 R.AQAALAVNISAAR.G 551.2 1 19/24
10108, 1 K.VHAELADVLTEAVVDSILAIK.K 1387.3 1 22/40
219 aldo-keto reductase family 1 member C1 36788.1 5453543
2 (2 0 0
0 0)
6711, 1 K.DIVLVAYSALGSHR.E 806.8 1 16/26
8474, 1 K.NLQLDYVDLYLIHFPVSVKPGEEVIPK.D
856.1 1 30/104
220 sulfotransferase 1A2 34310.4 4507303
3 (3 0 0
0 0)
5489, 1 K.DVAVSYYHFYHMAK.V 563.0 1 19/26
7334, 2-2 K.THLPLALLPQTLLDQK.V 621.1 1 17/30
7583, 1-2 K.THLPLALLPQTLLDQK.V 862.4 1 20/30
221 argininosuccinate lyase isoform 1 51657.7 68303542
2 (2 0 0
0 0)
7293, 1 R.INVLPLGSGAIAGNPLGVDR.E 1516.2 1 24/38
9304, 1 R.QTCSTLSGLLWELIR.T 715.6 1 14/28
222 vigilin isoform b 137969.8
34519928
3
2 (2 0 0
0 0)
4546, 1-2 K.AACLESAQEPAGAWGNK.I 749.4 1 17/32
6794, 1 K.ASVITQVFHVPLEER.K 606.7 1 14/28
223 pyruvate kinase isozymes R/L isoform 1 61829.8 10835121
2 (2 0 0
0 0)
5975, 1-2 R.TGILQGGPESEVELVK.G 903.3 1 20/30
6630, 1-2 K.GVNLPGAQVDLPGLSEQDVR.D 550.2 1 18/38
224 epoxide hydrolase 2 62615.4 27597073
5 (5 0 0
0 0)
7002, 2-2 K.ASPSEVVFLDDIGANLKPAR.D 639.8 1 16/38
7232, 1-2 K.ASPSEVVFLDDIGANLKPAR.D 1537.3 1 22/38
7352, 1 K.ASPSEVVFLDDIGANLKPAR.D 1161.2 1 21/38
7512, 2-2 K.GFTTAILTNTWLDDR.A 1730.1 1 19/28
7763, 1-2 K.GFTTAILTNTWLDDR.A 1515.5 1 18/28
225 L-serine dehydratase/L-threonine deaminase 34625.1 33469958
2 (2 0 0
0 0)
7506, 1 K.LFQEHPIFSEVISDQEAVAAIEK.F 1550.4 1 33/88
7553, 1 K.ILVEPACGAALAAVYSHVIQK.L 777.6 1 19/40
226 heat shock protein HSP 90-alpha isoform 1 98160.4
15379259
0
4 (4 0 0
0 0)
5164, 1 R.ELISNSSDALDKIR.Y 789.6 1 17/26
5291, 2-2 R.NPDDITNEEYGEFYK.S 929.7 1 20/28
5442, 1-2 R.NPDDITNEEYGEFYK.S 524.2 1 20/28
5559, 1 R.NPDDITNEEYGEFYK.S 698.4 1 23/28
227 3-ketoacyl-CoA thiolase, peroxisomal isoform a 44291.8 4501853 2 (2 0 0
Page 99
0 0)
5739, 1 K.VNPLGGAVALGHPLGCTGAR.Q 1150.1 1 22/38
7170, 2-2 R.IAQFLSDIPETVPLSTVNR.Q 925.4 1 20/36
228 tubulin alpha-1B chain 50151.3 57013276
4 (4 0 0
0 0)
6938, 2-2 R.SIQFVDWCPTGFK.V 1497.3 1 19/24
8336, 2-2 R.LISQIVSSITASLR.F 748.2 1 14/26
8548, 1-2 R.LISQIVSSITASLR.F 1270.8 1 19/26
8619, 1 R.LISQIVSSITASLR.F 1275.1 1 19/26
229 60S ribosomal protein L18 21634.3 4506607
3 (3 0 0
0 0)
5025, 2-2 K.TAVVVGTITDDVR.V 1838.1 1 20/24
5184, 1-2 K.TAVVVGTITDDVR.V 1340.3 1 20/24
6696, 2-2 K.ILTFDQLALDSPK.G 1154.9 1 16/24
230 kynurenine 3-monooxygenase 55809.7
18796004
5
3 (3 0 0
0 0)
4606, 2-2 K.SQYILSVSR.E 1299.2 1 15/16
7062, 2-2 K.AVDSLEQISNLISR.- 2091.7 1 19/26
7277, 1-2 K.AVDSLEQISNLISR.- 2106.6 1 20/26
231 heat shock protein HSP 90-beta 83263.6 20149594
3 (3 0 0
0 0)
5358, 2-2 K.SLTNDWEDHLAVK.H 1287.2 1 17/24
5512, 1-2 K.SLTNDWEDHLAVK.H 1751.0 1 19/24
5529, 1-2 R.NPDDITQEEYGEFYK.S 910.2 1 17/28
232 short-chain dehydrogenase/reductase 3 33548.2 31543615
2 (2 0 0
0 0)
5721, 1-2 K.SQHINTLGQFWTTK.A 1615.9 1 19/26
6584, 1 R.VRFPNLFPPLKPETVAR.R 710.8 1 25/64
233 leukotriene-B(4) omega-hydroxylase 1 precursor 59853.2 13435391
3 (3 0 0
0 0)
4317, 2-2 R.SVINASAAIAPK.D 1492.7 1 17/22
6026, 2-2 R.VLTQLVATYPQGFK.V 959.5 1 16/26
6302, 1 R.VLTQLVATYPQGFK.V 1057.2 1 17/26
234 ras-related protein Rap-1b isoform 2 16033.3
35445935
0
4 (4 0 0
0 0)
7553, 2-2 K.SKINVNEIFYDLVR.Q 891.9 1 16/26
7914, 1 K.SKINVNEIFYDLVR.Q 1025.1 1 17/26
8430, 2-2 K.INVNEIFYDLVR.Q 1870.7 1 20/22
8709, 1-2 K.INVNEIFYDLVR.Q 1333.1 1 18/22
235 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform 3 67523.9
31698315
8
2 (2 0 0
0 0)
7053, 1-2 K.VLFLLGADGGCITR.Q 1756.0 1 22/26
7524, 1-2 R.NDGAAILAAVSSIAQK.I 1364.9 1 21/30
236 importin-5 125544.3 24797086
2 (2 0 0
0 0)
3706, 2-2 K.TKENVNATENCISAVGK.I 1010.5 1 17/32
6462, 2-2 K.VIAALLQTMEDQGNQR.V 519.3 1 14/30
237 ATP synthase subunit O, mitochondrial precursor 23277.2 4502303
2 (2 0 0
0 0)
4913, 2-2 K.VAASVLNPYVK.R 1043.2 1 16/20
8320, 2-2 R.FSPLTTNLINLLAENGR.L 1449.9 1 19/32
238 acetolactate synthase-like protein 67867.3 21361361 2 (2 0 0
Page 100
0 0)
7084, 2-2 R.GALQAVDQLSLFRPLCK.F 525.3 1 13/32
8015, 1 R.FIFTLVGGHISPLLVACEK.L 1920.0 1 34/72
239 catenin beta-1 85496.2 4503131
3 (3 0 0
0 0)
7458, 1-2 R.NEGVATYAAAVLFR.M 1156.2 1 18/26
7576, 1 R.NEGVATYAAAVLFR.M 1293.9 1 18/26
10019, 1 R.GLNTIPLFVQLLYSPIENIQR.V 913.3 1 21/40
240 UDP-glucuronosyltransferase 1-1 precursor 59591.1 8850236
2 (2 0 0
0 0)
6562, 1 R.GHEIVVLAPDASLYIR.D 1065.2 1 20/30
10096, 1 R.EVTVQDLLSSASVWLFR.S 1030.2 1 20/32
241 oxysterol-binding protein 1 89420.0 4505531
2 (2 0 0
0 0)
5594, 1-2 R.LTEDLEYHELLDR.A 1374.8 1 19/24
5888, 1-2 R.SLSELESLKLPAESNEK.I 518.9 1 16/32
242 vesicle-trafficking protein SEC22b precursor 24593.2 94429050
2 (2 0 0
0 0)
5435, 1-2 R.NLGSINTELQDVQR.I 1004.7 1 19/26
7022, 1-2 R.IMVANIEEVLQR.G 2139.9 1 20/22
243 cytochrome P450 3A4 isoform 2 57255.8
32230235
1
3 (3 0 0
0 0)
5841, 2-2 K.GVVVMIPSYALHR.D 642.8 1 18/24
5996, 1-2 K.GVVVMIPSYALHR.D 648.3 1 18/24
6712, 1-2 K.LSLGGLLQPEKPVVLK.V 536.1 1 17/30
244 transmembrane 9 superfamily member 2 precursor 75775.3 4758874
2 (2 0 0
0 0)
5884, 2-2 K.RPSENLGQVLFGER.I 603.8 1 14/26
6638, 2-2 R.FCNPGFPIGCYITDK.G 969.3 1 22/28
245 OCIA domain-containing protein 1 isoform 1 27626.0 8923427
2 (2 0 0
0 0)
7974, 1-2 R.SVPLAATSMLITQGLISK.G 612.4 1 15/34
9071, 1 K.LILACIMGYFAGK.L 1881.2 1 19/24
246 carbonyl reductase [NADPH] 1 30374.7 4502599
2 (2 0 0
0 0)
7059, 1 R.SETITEEELVGLMNK.F 566.7 1 16/28
7776, 1 K.EYGGLDVLVNNAGIAFK.V 848.6 1 18/32
247 hydroxyacid oxidase 1 40924.1 11068137
2 (2 0 0
0 0)
5338, 1-2 R.NVAETDLSTSVLGQR.V 1833.5 1 22/28
8741, 1 K.GVQDVLEILKEEFR.L 1164.6 1 17/26
248 transmembrane protein 205 21197.7 63055043
3 (3 0 0
0 0)
3987, 2-2 R.GLGGEVPGSHQGPDPYR.Q 538.1 1 17/32
4064, 1-2 R.GLGGEVPGSHQGPDPYR.Q 507.1 1 17/32
6348, 2-2 R.TTAAMWALQTVEK.E 1570.6 1 18/24
249 apolipoprotein(a) precursor 226543.6
11629275
0
2 (2 0 0
0 0)
4368, 2-2 R.NPDAVAAPYCYTR.D 556.6 1 15/24
6263, 2-2 R.TPEYYPNAGLIMNYCR.N 639.3 1 19/30
250 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform a 109255.5 28373103
2 (2 0 0
0 0)
5806, 2-2 R.SLPSVETLGCTSVICSDK.T 574.6 1 17/34
Page 101
5842, 2-2 K.VGEATETALTCLVEK.M 1575.8 1 20/28
251 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 39095.4 31542303
2 (2 0 0
0 0)
8516, 1 R.SGWLTGWLPTWCPTSISHLK.E 823.5 1 27/76
9058, 1 R.FDSDAEEVENQFVESIEEWR.C 811.1 1 19/38
252 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase 58068.1
16636272
4
2 (2 0 0
0 0)
7145, 1-2 K.LGALQHTPVLDSVVEETLR.L 503.0 1 23/72
10043, 1 K.EGISNWLGNMLQFLR.E 585.1 1 15/28
253 3-mercaptopyruvate sulfurtransferase isoform 2 33178.2 61835204
2 (2 0 0
0 0)
7654, 1 R.ALVSAQWVAEALR.A 2605.1 1 20/24
8176, 1-2 R.AGQPLQLLDASWYLPK.L 560.4 1 15/30
254 ER lumen protein retaining receptor 2 isoform 1 24421.7 5803050
2 (2 0 0
0 0)
8674, 1-2 R.ALYLVNWIWR.F 680.6 3 12/18
10124, 1 R.LTGDLSHLAAIVILLLK.I 992.4 1 16/32
255 MOSC domain-containing protein 2, mitochondrial precursor 38023.2 31542713
3 (3 0 0
0 0)
5289, 2-2 K.GVPVSEAECTAMGLR.S 707.0 1 18/28
5560, 2-2 R.CILTTVDPDTGVIDR.K 1289.3 1 20/28
5723, 1-2 R.CILTTVDPDTGVIDR.K 710.9 1 16/28
256 myosin-Ia 118399.8 4885503
3 (3 0 0
0 0)
5682, 1-2 K.LVMSYVAAVCGK.G 1444.1 1 16/22
7155, 2-2 K.EQLLQSNPVLEAFGNAK.T 967.0 1 17/32
7408, 1-2 K.EQLLQSNPVLEAFGNAK.T 879.9 1 17/32
257 60 kDa heat shock protein, mitochondrial 61054.2 31542947
2 (2 0 0
0 0)
4445, 2-2 K.NAGVEGSLIVEK.I 999.2 1 17/22
9665, 2-2 R.ALMLQGVDLLADAVAVTMGPK.G 1344.2 1 30/80
258 signal transducer and activator of transcription 3 isoform 1 88067.3 21618340
5 (5 0 0
0 0)
6027, 2-2 K.LLGPGVNYSGCQITWAK.F 550.1 1 15/32
6209, 1-2 K.LLGPGVNYSGCQITWAK.F 675.2 1 19/32
6294, 1 K.LLGPGVNYSGCQITWAK.F 511.2 1 17/32
6683, 2-2 R.GLSIEQLTTLAEK.L 1335.7 1 17/24
6897, 1-2 R.GLSIEQLTTLAEK.L 1698.8 1 19/24
259 plastin-2 70288.0
16761450
6
2 (2 0 0
0 0)
8711, 1 K.VNDDIIVNWVNETLR.E 1172.0 1 20/28
9114, 1 K.LNLAFIANLFNR.Y 1067.5 1 16/22
260 importin subunit beta-1 97169.7 19923142
3 (3 0 0
0 0)
7145, 2-2 K.LAATNALLNSLEFTK.A 1371.7 1 18/28
7510, 1 K.LAATNALLNSLEFTK.A 1909.1 1 22/28
8429, 1-2 R.AAVENLPTFLVELSR.V 542.2 1 18/28
261 dehydrogenase/reductase SDR family member 7 precursor 38298.5 7706318
2 (2 0 0
0 0)
6454, 2-2 K.EKDILVLPLDLTDTGSHEAATK.A 1125.5 1 30/84
7078, 2-2 K.DILVLPLDLTDTGSHEAATK.A 605.3 1 20/38
Page 102
262 vacuolar protein sorting-associated protein 13C isoform 1B 403082.1 66348091
2 (2 0 0
0 0)
6232, 1 K.LNAFCVIVCNEK.N 781.0 1 14/22
6934, 2-2 R.VLLFTDDVALVSK.A 629.4 1 14/24
263 cytochrome P450 2A7 isoform 1 precursor 56424.8 15147330
2 (2 0 0
0 0)
5153, 2-2 R.EALVDQAEEFSGR.G 1051.6 1 18/24
6890, 2-2 R.GEQATFDWVFK.G 1184.6 1 16/20
264 ras-related protein Rab-2B isoform 2 19005.1
25428134
5
3 (3 0 0
0 0)
5940, 2-2 K.LQIWDTAGQESFR.S 1690.7 1 19/24
6180, 1 K.LQIWDTAGQESFR.S 1007.0 1 19/24
6714, 2-2 R.GAAGALLVYDITR.R 1022.7 1 16/24
265 UDP-glucuronosyltransferase 2B10 isoform 2 precursor 50688.0
22121905
9
3 (3 0 0
0 0)
8162, 2-2 K.TEFENIIM*QLVK.R 585.9 1 13/22
8583, 2-2 K.TEFENIIMQLVK.R 1137.7 1 16/22
8858, 1-2 K.TEFENIIMQLVK.R 1379.9 1 16/22
266 S-adenosylmethionine synthase isoform type-1 43647.7 4557737
2 (2 0 0
0 0)
4740, 2-2 R.FVIGGPQGDAGVTGR.K 710.2 1 19/28
5180, 1 K.YLDEDTVYHLQPSGR.F 885.7 1 16/28
267 alpha-soluble NSF attachment protein 33232.5 47933379
2 (2 0 0
0 0)
4763, 1 K.LLEAHEEQNVDSYTESVK.E 644.2 1 17/34
7143, 2-2 K.NSQSFFSGLFGGSSK.I 1042.8 1 17/28
268 hypoxia up-regulated protein 1 precursor 111334.8 5453832
2 (2 0 0
0 0)
4725, 1 K.LYQPEYQEVSTEEQR.E 923.3 1 19/28
7390, 1-2 K.AANSLEAFIFETQDK.L 1063.1 1 17/28
269 protein disulfide-isomerase A6 precursor 48121.0 5031973
2 (2 0 0
0 0)
5483, 2-2 R.GSTAPVGGGAFPTIVER.E 626.8 3 16/32
7857, 1-2 R.TGEAIVDAALSALR.Q 1380.6 1 19/26
270 40S ribosomal protein S8 24205.0 4506743
3 (3 0 0
0 0)
5393, 2-2 K.ISSLLEEQFQQGK.L 1270.1 1 17/24
5531, 1-2 K.ISSLLEEQFQQGK.L 1358.2 1 17/24
5874, 1-2 R.IIDVVYNASNNELVR.T 984.5 1 17/28
271 methyltransferase-like protein 7B precursor 27774.6
16466380
5
3 (3 0 0
0 0)
4037, 2-2 R.VTCLDPNPHFEK.F 795.1 1 17/22
4121, 1-2 R.VTCLDPNPHFEK.F 780.3 1 17/22
8463, 2-2 K.SYFPYLMAVLTPK.S 734.9 1 16/24
272 receptor expression-enhancing protein 6 20733.0 19923919
3 (3 0 0
0 0)
7568, 2-2 K.CAFLLFCMAPR.P 1132.6 1 15/20
9197, 2-2 R.NLVTEVLGALEAK.T 1657.4 1 18/24
9338, 1 R.NLVTEVLGALEAK.T 1402.0 1 18/24
273 argininosuccinate synthase 46530.1 16950633
2 (2 0 0
0 0)
6173, 1-2 K.APNTPDILEIEFKK.G 555.4 1 16/26
Page 103
7632, 1 K.FAELVYTGFWHSPECEFVR.H 1001.1 1 19/36
274 TRAM adaptor with GOLD domain isoform 2 precursor 21232.8
25698510
2
2 (2 0 0
0 0)
4518, 1-2 K.SVIDYQTHFR.L 1038.1 1 14/18
6192, 2-2 K.FCFSNEFSTFTHK.T 744.3 1 14/24
275 erlin-2 isoform 1 37839.3 6005721
3 (3 0 0
0 0)
4185, 2-2 K.VAQVAEITYGQK.V 1922.8 1 18/22
4272, 1-2 K.VAQVAEITYGQK.V 2008.4 1 18/22
6215, 2-2 K.LSFGLEDEPLETATKEN.- 1439.2 1 20/32
276 Golgi apparatus protein 1 isoform 2 precursor 135994.8
22458681
5
3 (3 0 0
0 0)
5300, 2-2 K.AKDDSELEGQVISCLK.L 779.7 1 18/30
5352, 2-2 R.IIIQESALDYR.L 1430.5 1 15/20
5560, 1 K.AKDDSELEGQVISCLK.L 528.7 1 19/30
277 3-hydroxyacyl-CoA dehydratase 3 43159.3
11716824
8
3 (3 0 0
0 0)
4779, 2-2 R.LESEGSPETLTNLR.K 646.5 1 16/26
5876, 2-2 K.RPLFLAPDFDR.W 1251.1 1 18/20
6030, 1-2 K.RPLFLAPDFDR.W 712.8 1 15/20
278 protein disulfide-isomerase A4 precursor 72931.9 4758304
2 (2 0 0
0 0)
4301, 2-2 K.IDATSASVLASR.F 1688.5 1 18/22
6743, 1-2 K.YGIVDYMIEQSGPPSK.E 682.1 1 18/30
279 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 37330.8 20357529
4 (4 0 0
0 0)
5967, 2-2 K.LIIWDSYTTNK.V 1103.4 1 16/20
6123, 1-2 K.LIIWDSYTTNK.V 784.4 1 14/20
6209, 1 K.LIIWDSYTTNK.V 1354.7 1 18/20
6288, 1 R.KACGDSTLTQITAGLDPVGR.I 510.2 1 16/38
280 myosin-14 isoform 3 232008.3
22483124
1
2 (2 0 0
0 0)
6172, 1 K.EQADFALEALAK.A 617.9 1 14/22
6777, 1-2 R.KQELELVVSELEAR.V 713.3 1 15/26
281 mitochondrial dicarboxylate carrier 31282.3 20149598
2 (2 0 0
0 0)
4722, 1-2 K.GEYQGVFHCAVETAK.L 890.3 1 17/28
5694, 1-2 R.GALVTVGQLSCYDQAK.Q 803.8 1 17/30
282 transmembrane emp24 domain-containing protein 9 precursor 27277.2 39725636
3 (3 0 0
0 0)
4500, 2-2 R.QLVEQVEQIQK.E 843.0 1 13/20
4637, 1-2 R.QLVEQVEQIQK.E 1134.4 1 17/20
7211, 1-2 K.FSLFAGGMLR.V 810.8 1 14/18
283 extended synaptotagmin-1 isoform 2 122855.6 14149680
2 (2 0 0
0 0)
4714, 1-2 K.LLAETVAPAVR.G 540.7 1 13/20
5286, 2-2 R.IHVLEAQDLIAK.D 1270.9 1 17/22
284 alpha-actinin-1 isoform b 103056.9 4501891
3 (3 0 0
0 0)
4958, 2-2 R.LAILGIHNEVSK.I 682.0 1 15/22
6018, 2-2 K.ICDQWDNLGALTQK.R 1629.4 1 18/26
6179, 1-2 K.ICDQWDNLGALTQK.R 623.0 1 16/26
Page 104
285 C4b-binding protein alpha chain precursor 67032.9 4502503
4 (4 0 0
0 0)
5142, 1-2 R.FSAICQGDGTWSPR.T 1430.0 1 19/26
6476, 2-2 K.LSLEIEQLELQR.D 1587.0 1 16/22
6674, 1-2 K.LSLEIEQLELQR.D 1934.2 1 17/22
6777, 1 K.LSLEIEQLELQR.D 1485.4 1 17/22
286 lysophospholipid acyltransferase 5 56034.7 42542394
3 (3 0 0
0 0)
4540, 2-2 K.LATSLGASEQALR.L 1382.6 1 19/24
6227, 2-2 K.VWLFETNPR.F 1164.4 1 15/16
6394, 1-2 K.VWLFETNPR.F 998.0 1 15/16
287 aspartyl/asparaginyl beta-hydroxylase isoform f 83267.4
25861394
3
2 (2 0 0
0 0)
6989, 1-2 K.GDWSQFTLWQQGR.R 681.5 1 13/24
8054, 1 R.LIFIVDVWHPELTPQQR.R 602.7 1 17/32
288 Golgi integral membrane protein 4 81879.8 7657138
2 (2 0 0
0 0)
4617, 2-2 K.SALAAAQTQVAEYK.Q 1504.3 1 18/26
4727, 2-2 K.FQSPYEEQLEQQR.L 602.1 1 13/24
289 vesicle-associated membrane protein-associated protein A isoform 1 32613.3 94721250
2 (2 0 0
0 0)
5735, 1-2 K.GPFTDVVTTNLK.L 1482.6 1 18/22
5842, 1-2 K.HEQILVLDPPTDLK.F 569.0 1 16/26
290 UDP-glucuronosyltransferase 1-6 isoform 1 precursor 60750.4 45827765
2 (2 0 0
0 0)
3874, 2-2 R.YQSFGNNHFAER.S 1239.3 1 17/22
4960, 2-2 R.SFLTAPQTEYR.N 625.1 1 15/20
291 ras-related protein Rab-2A isoform a 23545.4 4506365
2 (2 0 0
0 0)
5518, 1-2 K.TASNVEEAFINTAK.E 949.6 1 17/26
5794, 1-2 K.IQEGVFDINNEANGIK.I 516.0 1 15/30
292 ancient ubiquitous protein 1 45786.6 31712030
2 (2 0 0
0 0)
6075, 1 K.FPSSGPVTPQPTALTFAK.S 580.7 1 17/34
9089, 1 R.FSSWPFSIQDVVQPLTLQVQR.P 619.3 1 16/40
293 sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform b 114756.1 24638454
2 (2 0 0
0 0)
3746, 2-2 R.NYLEPGKECVQPATK.S 650.5 1 18/28
7500, 2-2 K.DIVPGDIVEIAVGDKVPADIR.L 602.5 1 18/40
294 endoplasmic reticulum-Golgi intermediate compartment protein 1 32592.1 72534712
3 (3 0 0
0 0)
5098, 2-2 R.YDLSPITVK.Y 869.4 1 14/16
5207, 2-2 R.LTSNPLASHDYILK.I 985.9 1 17/26
5368, 1-2 R.LTSNPLASHDYILK.I 641.8 1 15/26
295 ubiquitin-like modifier-activating enzyme 1 117848.1 23510340
2 (2 0 0
0 0)
6664, 1 R.QFLFRPWDVTK.L 632.5 1 14/20
8873, 1 R.IYDDDFFQNLDGVANALDNVDAR.M 776.7 1 20/44
296 EH domain-containing protein 3 60886.7 7657056
2 (2 0 0
0 0)
5916, 1-2 R.KLFEAEEQDLFR.D 602.8 1 14/22
6314, 1 K.ELVNNLAEIYGR.I 729.6 1 14/22
Page 105
297 protein transport protein Sec31A isoform 1 133013.8
11625633
8
2 (2 0 0
0 0)
5225, 1-2 R.NPAVLSAASFDGR.I 1424.2 1 18/24
6724, 1-2 R.ISVYSIMGGSTDGLR.Q 801.8 1 17/28
298 probable ATP-dependent RNA helicase DDX17 isoform 1 80272.0 38201710
2 (2 0 0
0 0)
5662, 1-2 R.ELAQQVQQVADDYGK.C 609.4 1 16/28
5717, 1 K.FVINYDYPNSSEDYVHR.I 534.1 1 17/32
299 stromal interaction molecule 1 precursor 77422.9 21070997
2 (2 0 0
0 0)
4073, 1-2 K.ATGTSSGANSEESTAAEFCR.I 618.2 1 18/38
7918, 1-2 K.ALDTVLFGPPLLTR.H 708.8 1 16/26
300 beta-galactoside alpha-2,6-sialyltransferase 1 isoform a 46604.3 27765091
2 (2 0 0
0 0)
4570, 2-2 K.AKPEASFQVWNK.D 702.6 1 17/22
4691, 2-2 R.FNGAPTANFQQDVGTK.T 752.1 1 17/30
301 transferrin receptor protein 2 isoform 2 69617.1
33230917
1
2 (2 0 0
0 0)
6624, 2-2 R.GLTLQWVYSAR.G 1144.5 1 16/20
9303, 2-2 K.TSPLLTSLIESVLK.Q 744.9 1 17/26
302 alpha-tocopherol transfer protein-like 38514.9 85861250
2 (2 0 0
0 0)
3626, 1-2 K.AREELQEKPEWR.L 537.1 1 13/22
7307, 1 R.KEYPNLSTSLDDAFLLR.F 668.6 1 15/32
303 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform 1 precursor 70729.6 66346721
2 (2 0 0
0 0)
6975, 2-2 R.LGTPVLQALGDGDFVK.C 690.4 1 14/30
7959, 1 K.GVPLVYEAFNWR.H 769.6 1 18/22
304 L-xylulose reductase isoform 2 25742.7
30457197
5
4 (4 0 0
0 0)
4797, 2-2 R.TQADLDSLVR.E 1131.1 1 15/18
4919, 1-2 R.TQADLDSLVR.E 1278.9 1 16/18
5189, 2-2 R.AVIQVSQIVAR.G 1105.4 1 15/20
5340, 1-2 R.AVIQVSQIVAR.G 1216.1 1 16/20
305 clusterin preproprotein 52494.3
35559475
3
2 (2 0 0
0 0)
4410, 2-2 R.ELDESLQVAER.L 736.1 1 15/20
7444, 2-2 R.ASSIIDELFQDR.F 515.3 1 12/22
306 reticulon-4 isoform C 22395.3 5902016
2 (2 0 0
0 0)
6749, 1-2 K.DKVVDLLYWR.D 977.2 1 14/18
6832, 2-2 K.VVDLLYWR.D 696.5 1 12/14
307 60S ribosomal protein L7 29225.6 15431301
2 (2 0 0
0 0)
3327, 2-2 K.TTHFVEGGDAGNREDQINR.L 798.5 1 18/36
4577, 2-2 K.AGNFYVPAEPK.L 817.5 2 13/20
308 tubulin beta-8 chain isoform 1 49775.7 42558279
2 (1 1 0
0 0)
6194, 1-2 R.AVLVDLEPGTMDSVR.S 665.9 1 18/28
7094, 1-2 K.EAESCDCLQGFQLTHSLGGGTGSGMGTLLLSK.I
1051.2 1 31/124
309 cytochrome P450 4F8 precursor 59994.3 6005737 2 (1 1 0
Page 106
0 0)
5298, 1 R.LVHDFTDAVIQER.R 1465.7 1 19/24
7962, 2-2 K.TLDFIDVLLLSEDKNGK.E 615.8 2 14/32
310 cytochrome P450 4A22 59245.5 62952506
2 (1 1 0
0 0)
3974, 2-2 R.ACQLAHQHTDQVIQLR.K 997.7 1 25/60
5348, 1 R.NAFHENDTIYSLTSAGR.W 818.5 2 19/32
311 HLA class I histocompatibility antigen, Cw-1 alpha chain precursor 40648.3 52630342
2 (1 1 0
0 0)
5021, 2-2 R.SWTAADTAAQITQR.K 1643.7 1 20/26
6630, 1 R.AYLEGTCVEWLR.R 1615.3 1 19/22
312 guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 40450.7 4504041
3 (1 2 0
0 0)
5268, 2-2 K.LLLLGAGESGK.S 1077.1 1 16/20
5392, 1 K.TTGIVETHFTFK.D 532.0 1 14/22
5398, 1-2 K.LLLLGAGESGK.S 933.4 1 16/20
313 myosin-11 isoform SM2A 223574.8 13124875
2 (1 1 0
0 0)
4038, 1-2 K.KEEELQAALAR.L 1122.4 1 16/20
5081, 1-2 K.KQELEEILHEM*EAR.L 674.9 2 13/26
314 heat shock 70 kDa protein 1A/1B 70051.8
19424807
2
3 (1 2 0
0 0)
4828, 2-2 K.AQIHDLVLVGGSTR.I 956.3 1 16/26
4961, 1-2 K.AQIHDLVLVGGSTR.I 706.7 1 16/26
6254, 1 R.ARFEELCSDLFR.S 795.1 1 16/22
315 electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor 68495.0
11970374
6
2 (2 0 0
0 0)
8127, 2-2 K.SGILAAESIFNQLTSENLQSK.T 1596.8 1 23/40
8391, 1-2 K.SGILAAESIFNQLTSENLQSK.T 1121.5 1 20/40
316 short/branched chain specific acyl-CoA dehydrogenase, mitochondrial precursor 47485.1 4501859
1 (1 0 0
0 0)
8132, 1 R.LFDFQGLQHQVAHVATQLEAAR.L 1084.2 1 30/84
317 sepiapterin reductase 28048.3 4507185
2 (2 0 0
0 0)
8798, 1-2 R.VPADLGAEAGLQQLLGALR.E 1193.7 1 21/36
8808, 1-2 R.VPADLGAEAGLQQLLGALR.E 1583.9 1 22/36
318 erythrocyte band 7 integral membrane protein isoform a 31730.6 38016911
3 (3 0 0
0 0)
5164, 2-2 R.VQNATLAVANITNADSATR.L 1131.5 1 21/36
5451, 1 R.VQNATLAVANITNADSATR.L 770.3 1 20/36
5465, 1 R.VQNATLAVANITNADSATR.L 1177.9 1 21/36
319 phenylalanine-4-hydroxylase 51861.8 4557819
1 (1 0 0
0 0)
8457, 1 K.ILADSINSEIGILCSALQK.I 2088.2 1 34/72
320 retinal dehydrogenase 1 54861.5 21361176
2 (2 0 0
0 0)
6839, 1-2 K.LYSNAYLNDLAGCIK.T 778.5 1 17/28
6936, 1 K.LYSNAYLNDLAGCIK.T 2608.8 1 24/28
321 membrane primary amine oxidase 84621.4 4502119
1 (1 0 0
0 0)
Page 107
7678, 1 R.GDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN.-
599.3 1 30/144
322 glutathione S-transferase kappa 1 isoform a 25496.7 7705704
2 (2 0 0
0 0)
6105, 1-2 R.NEDITEPQSILAAAEK.A 916.9 1 21/30
6201, 1 R.NEDITEPQSILAAAEK.A 693.7 1 18/30
323 nicotinamide N-methyltransferase 29573.8 5453790
1 (1 0 0
0 0)
5918, 1-2 K.EIVVTDYSDQNLQELEK.W 1884.1 1 23/32
324 apolipoprotein C-III precursor 10852.2 4557323
1 (1 0 0
0 0)
4358, 2-2 K.DALSSVQESQVAQQAR.G 2145.4 1 22/30
325 inter-alpha-trypsin inhibitor heavy chain H1 isoform a 101388.4
15611962
5
1 (1 0 0
0 0)
5063, 1 R.FAHYVVTSQVVNTANEAR.E 1154.0 1 20/34
326 apoptosis-inducing factor 2 40526.4 14318424
1 (1 0 0
0 0)
6988, 1 K.TEYPEKEVTLIHSQVALADKELLPSVR.Q
972.0 1 30/104
327 annexin A2 isoform 2 38603.8
20986283
1
1 (1 0 0
0 0)
5697, 1 K.TDLEKDIISDTSGDFRK.L 2734.7 1 34/64
328 GDH/6PGL endoplasmic bifunctional protein precursor 88892.2 52145310
1 (1 0 0
0 0)
6966, 1 K.TAEDYQALNKDIEAQLQHAGLR.E 1056.1 1 31/84
329 cystathionine beta-synthase 60586.2 4557415
1 (1 0 0
0 0)
8319, 1 R.VQELGLSAPLTVLPTITCGHTIEILR.E
725.1 1 30/100
330 protein PRRC1 46700.9 18677735
1 (1 0 0
0 0)
7001, 2-2 R.GQDEASAGGIWGFIK.G 1676.4 1 21/28
331 rRNA 2'-O-methyltransferase fibrillarin 33784.0 12056465
1 (1 0 0
0 0)
7964, 1 K.VLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR.S
1076.8 1 32/128
332 POTE ankyrin domain family member F 121443.8
15379135
2
6 (6 0 0
0 0)
6024, 1 K.SYELPDGQVITIGNER.F 711.0 1 19/30
6200, 2-2 K.SYELPDGQVITIGNER.F 1029.6 1 20/30
6222, 2-2 K.SYELPDGQVITIGNER.F 1098.8 1 21/30
6366, 1-2 K.SYELPDGQVITIGNER.F 1046.0 1 21/30
6441, 1-2 K.SYELPDGQVITIGNER.F 932.6 1 20/30
12062, 1 K.SYELPDGQVITIGNER.F 585.0 1 16/30
333 plasminogen isoform 1 precursor 90568.6 4505881
1 (1 0 0
0 0)
5140, 2-2 R.NPDGDVGGPWCYTTNPR.K 1142.3 1 20/32
334 40S ribosomal protein S5 22876.3 13904870
1 (1 0 0
0 0)
6536, 2-2 R.VNQAIWLLCTGAR.E 1397.6 1 18/24
335 nicotinamide phosphoribosyltransferase precursor 55520.8 5031977
1 (1 0 0
0 0)
Page 108
8988, 1 R.TPAGNFVTLEEGKGDLEEYGQDLLHTVFK.N
901.9 1 28/112
336 cytochrome b-c1 complex subunit 1, mitochondrial precursor 52645.5 46593007
1 (1 0 0
0 0)
5106, 2-2 R.NALVSHLDGTTPVCEDIGR.S 1485.3 1 22/36
337 prolow-density lipoprotein receptor-related protein 1 precursor 504608.8
12601256
2
1 (1 0 0
0 0)
6988, 2-2 R.AALSGANVLTLIEK.D 1336.3 1 20/26
338 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial isoform 1 precursor
48755.0 19923748
1 (1 0 0
0 0)
7491, 1 K.ASAFALQEQPVVNAVIDDTTK.E 832.5 1 20/40
339 OCIA domain-containing protein 2 isoform 1 16953.4 62244044
1 (1 0 0
0 0)
8068, 1-2 K.VALAGLLGFGLGK.V 2056.5 1 21/24
340 coatomer subunit gamma-2 97621.8
10913434
9
3 (3 0 0
0 0)
8108, 2-2 R.SIATLAITTLLK.T 2042.7 1 19/22
8366, 1-2 R.SIATLAITTLLK.T 1916.1 1 19/22
8445, 1 R.SIATLAITTLLK.T 1859.0 1 19/22
341 large proline-rich protein BAG6 isoform a 119408.2
14915869
2
1 (1 0 0
0 0)
5060, 1 R.SFFHQHYLGGQEPTPSNIR.M 943.6 1 31/72
342 heterogeneous nuclear ribonucleoprotein U isoform a 90584.0 74136883
2 (2 0 0
0 0)
5331, 2-2 R.NFILDQTNVSAAAQR.R 2610.9 1 23/28
5591, 1 R.NFILDQTNVSAAAQR.R 1203.0 1 21/28
343 thymidine phosphorylase precursor 49955.2
16615892
2
1 (1 0 0
0 0)
8481, 1 R.ALPLALVLHELGAGR.S 1698.3 1 21/28
344 gamma-glutamyltransferase 5 isoform b 62260.8
15326688
5
1 (1 0 0
0 0)
7928, 1 R.ETVPASHAPSLLDQCAQALPLGTGAQWIGVPGELR.G
689.5 1 34/136
345 heterogeneous nuclear ribonucleoprotein H2 49263.3 9624998
2 (2 0 0
0 0)
6754, 2-2 R.STGEAFVQFASQEIAEK.A 1349.3 1 19/32
6971, 1-2 R.STGEAFVQFASQEIAEK.A 1085.9 1 18/32
346 fermitin family homolog 2 isoform 3 72396.9
20186182
3
1 (1 0 0
0 0)
5302, 1-2 R.ILEAHQNVAQMSLIEAK.M 1795.7 1 22/32
347 UDP-glucose 6-dehydrogenase isoform 1 55023.8 4507813
1 (1 0 0
0 0)
6886, 1 R.AVQALCAVYEHWVPR.E 1535.4 1 19/28
348 UDP-N-acetylglucosamine transporter 35984.2 6912668
1 (1 0 0
0 0)
4847, 2-2 R.VLHDEILNKPMETLK.L 1820.0 1 20/28
349 5'-AMP-activated protein kinase subunit gamma-1 isoform 1 37579.1 4506061
1 (1 0 0
0 0)
9923, 1 K.GIVSLSDILQALVLTGGEK.K 1579.8 1 20/36
350 transmembrane protein 33 27978.0 22458912 2 (2 0 0
Page 109
7 0 0)
6676, 2-2 R.ALLANALTSALR.L 2464.9 1 20/22
6875, 1-2 R.ALLANALTSALR.L 2337.2 1 20/22
351 gap junction beta-1 protein 32024.3 4504005
1 (1 0 0
0 0)
7572, 1 K.SSFICNTLQPGCNSVCYDQFFPISHVR.L
566.7 1 28/104
352 PRA1 family protein 3 21614.6 5453704
1 (1 0 0
0 0)
8559, 1 R.TPMGIVLDALEQQEEGINR.L 1073.4 1 20/36
353 B-cell receptor-associated protein 31 isoform b 27991.4
21351101
2
1 (1 0 0
0 0)
7638, 1 R.LVTLISQQATLLASNEAFK.K 1167.0 1 20/36
354 RNA-binding protein EWS isoform 2 68477.8 4885225
1 (1 0 0
0 0)
5794, 1 R.AGDWQCPNPGCGNQNFAWR.T 534.0 1 17/36
355 long-chain-fatty-acid--CoA ligase 4 isoform 2 79187.6 12669909
1 (1 0 0
0 0)
8548, 1 R.SVTHFDSLAVIDIPGADTLDKLFDHAVSK.F
1104.1 1 33/112
356 bile acid-CoA:amino acid N-acyltransferase 46298.9 4502351
1 (1 0 0
0 0)
9203, 1 R.KPEVTDLEYFEEAANFLLR.H 671.3 1 18/36
357 elongation factor 1-alpha 1 50140.5 4503471
3 (3 0 0
0 0)
4956, 2-2 K.YYVTIIDAPGHR.D 1105.9 1 17/22
5092, 1-2 K.YYVTIIDAPGHR.D 969.0 1 16/22
5096, 1-2 K.YYVTIIDAPGHR.D 1250.0 1 18/22
358 sec1 family domain-containing protein 1 isoform a 72379.4 33469966
1 (1 0 0
0 0)
6922, 2-2 K.ALTDAGCNLNPLQYIK.Q 747.8 1 16/30
359 ceramide synthase 2 44875.8 31077094
1 (1 0 0
0 0)
5543, 1-2 R.APPNATLEHFYLTSGK.Q 871.7 1 19/30
360 leucine-rich repeat-containing protein 59 34930.2 40254924
1 (1 0 0
0 0)
5993, 2-2 R.LVNLQHLDLLNNK.L 1216.0 1 15/24
361 serine/threonine-protein kinase PAK 2 58042.3 32483399
1 (1 0 0
0 0)
5112, 1 K.GTEAPAVVTEEEDDDEETAPPVIAPRPDHTK.S
845.8 1 36/120
362 cytochrome c oxidase subunit II 25564.8
25183111
0
1 (1 0 0
0 0)
6401, 1-2 R.ILYMTDEVNDPSLTIK.S 737.6 1 16/30
363 glucose-6-phosphate isomerase isoform 2 63146.7 18201905
1 (1 0 0
0 0)
9335, 1 K.ILLANFLAQTEALMR.G 1178.5 1 18/28
364 epiplakin 555623.1
20745273
5
1 (1 0 0
0 0)
5301, 1-2 R.LLEAQIATGGVIDPVHSHR.V 1021.3 1 31/72
365 proteasome activator complex subunit 1 isoform 1 28722.9 5453990
1 (1 0 0
0 0)
8612, 1 R.NAYAVLYDIILK.N 1593.4 1 18/22
Page 110
366 phosphatidate cytidylyltransferase 2 51417.7 20143480
1 (1 0 0
0 0)
5606, 1-2 R.AESAPLPVSADDTPEVLNR.A 695.9 1 19/36
367 retinol dehydrogenase 11 isoform 1 precursor 35386.0
16679526
8
1 (1 0 0
0 0)
4014, 2-2 K.EIQTTTGNQQVLVR.K 1493.7 1 19/26
368 L-lactate dehydrogenase A chain isoform 1 36688.5 5031857
1 (1 0 0
0 0)
9394, 1 K.LLIVSNPVDILTYVAWK.I 538.6 1 17/32
369 ATP-binding cassette sub-family D member 1 82936.5 7262393
1 (1 0 0
0 0)
4104, 2-2 R.GLQAPAGEPTQEASGVAAAK.A 850.0 1 22/38
370 ubiquitin-60S ribosomal protein L40 precursor 14728.2 77539055
1 (1 0 0
0 0)
5936, 1 K.TITLEVEPSDTIENVK.A 517.0 1 17/30
371 myeloperoxidase precursor 83868.1 4557759
1 (1 0 0
0 0)
8141, 1 R.VGPLLACIIGTQFR.K 1704.2 1 19/26
372 uridine 5'-monophosphate synthase 52221.3 4507835
2 (2 0 0
0 0)
7992, 1-2 R.AALGPLVTGLYDVQAFK.F 698.2 1 18/32
8153, 1 R.AALGPLVTGLYDVQAFK.F 683.5 1 17/32
373 voltage-dependent anion-selective channel protein 2 isoform 1 33371.4
29631733
7
1 (1 0 0
0 0)
5907, 2-2 K.YKWCEYGLTFTEK.W 727.7 1 13/24
374 annexin A5 35936.5 4502107
1 (1 0 0
0 0)
8600, 1 K.GLGTDEESILTLLTSR.S 1094.8 1 18/30
375 UDP-glucuronosyltransferase 2A3 precursor 60254.1
19321142
7
2 (2 0 0
0 0)
6921, 2-2 K.ANIIASALAQIPQK.V 560.1 1 16/26
7161, 1-2 K.ANIIASALAQIPQK.V 1619.8 1 21/26
376 clathrin interactor 1 isoform 1 70294.4
30707812
3
1 (1 0 0
0 0)
9280, 1-2 K.SLLLLAYLIR.N 1683.5 1 16/18
377 short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor 44297.0 4557233
1 (1 0 0
0 0)
10034, 1 R.IGIASQALGIAQTALDCAVNYAENR.M
773.2 1 24/96
378 microsomal glutathione S-transferase 3 16516.2 4758714
3 (3 0 0
0 0)
7478, 2-2 R.IASGLGLAWIVGR.V 1957.6 1 20/24
7718, 1-2 R.IASGLGLAWIVGR.V 1999.4 1 20/24
7865, 1 R.IASGLGLAWIVGR.V 2303.8 1 21/24
379 dual specificity mitogen-activated protein kinase kinase 2 44423.9 13489054
1 (1 0 0
0 0)
5639, 2-2 K.ELEAIFGRPVVDGEEGEPHSISPR.P
730.2 1 26/92
380 peroxisomal membrane protein 2 22252.4 8923892
2 (2 0 0
0 0)
7938, 2-2 R.ALAQYLLFLR.L 1603.8 1 16/18
8204, 1-2 R.ALAQYLLFLR.L 1881.1 1 17/18
Page 111
381 COP9 signalosome complex subunit 7a 30276.4 7705330
1 (1 0 0
0 0)
5028, 1 K.VTTAAAAAATSQDPEQHLTELREPAPGTNQR.Q
577.5 1 31/120
382 protein odr-4 homolog isoform 1 51102.8 57527756
1 (1 0 0
0 0)
5129, 1 K.AKLDNLDEEWATEHACQVSR.M 721.2 1 25/76
383 inverted formin-2 isoform 1 135623.5
14999938
0
1 (1 0 0
0 0)
7683, 1 R.ALDELFEAIEQK.Q 651.8 1 17/22
384 fructose-1,6-bisphosphatase 1 36842.3
18908369
2
1 (1 0 0
0 0)
5813, 1 K.EAVLDVIPTDIHQR.A 800.9 1 19/26
385 lanosterol synthase isoform 1 83308.3 47933395
2 (2 0 0
0 0)
5991, 2-2 R.SVQLPDGGWGLHIEDK.S 1097.8 1 22/30
6243, 1 R.SVQLPDGGWGLHIEDK.S 1203.1 1 23/30
386 cytoplasmic aconitate hydratase 98398.2 8659555
1 (1 0 0
0 0)
7758, 1 K.QAPQTIHLPSGEILDVFDAAER.Y 1057.7 1 30/84
387 40S ribosomal protein S3a 29944.7 4506723
2 (2 0 0
0 0)
5902, 2-2 K.ACQSIYPLHDVFVR.K 1038.9 1 20/26
6057, 1-2 K.ACQSIYPLHDVFVR.K 892.1 1 19/26
388 alpha-enolase isoform 1 47168.7 4503571
1 (1 0 0
0 0)
7246, 1 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L
1029.0 1 35/116
389 ras-related protein Rab-8A 23668.1 16933567
1 (1 0 0
0 0)
7377, 2-2 K.ANINVENAFFTLAR.D 1817.2 1 21/26
390 UDP-glucuronosyltransferase 1-9 precursor 59940.7 11276085
3 (3 0 0
0 0)
6237, 2-2 K.TYSTSYTLEDLDREFK.A 737.5 1 14/30
6425, 1-2 K.TYSTSYTLEDLDREFK.A 900.5 1 15/30
6500, 1 K.TYSTSYTLEDLDREFK.A 621.2 1 15/30
391 carbonic anhydrase 2 29245.8 4557395
1 (1 0 0
0 0)
8955, 1 K.AVQQPDGLAVLGIFLK.V 747.8 1 19/30
392 guanidinoacetate N-methyltransferase isoform a 26318.0 4503909
1 (1 0 0
0 0)
6633, 1-2 K.VQEAPIDEHWIIECNDGVFQR.L 537.7 1 25/80
393 cathepsin B preproprotein 37821.4 4503139
1 (1 0 0
0 0)
8638, 1 K.NGPVEGAFSVYSDFLLYK.S 1361.5 1 20/34
394 alcohol dehydrogenase 6 isoform 2 39072.4 4501939
1 (1 0 0
0 0)
7332, 1 K.LNLDPLITHTLNLDK.I 779.0 1 18/28
395 aldo-keto reductase family 1 member C4 37094.6
32565208
3
1 (1 0 0
0 0)
8950, 1 K.LWVDPNSPVLLEDPVLCALAK.K 702.0 1 18/40
396 60S ribosomal protein L27 15797.6 4506623
1 (1 0 0
0 0)
Page 112
5022, 1 K.NIDDGTSDRPYSHALVAGIDR.Y 506.2 1 23/80
397 60S ribosomal protein L19 23465.8 4506609
1 (1 0 0
0 0)
5436, 2-2 K.VWLDPNETNEIANANSR.Q 890.5 1 18/32
398 nodal modulator 1 precursor 134323.0 51944953
1 (1 0 0
0 0)
7433, 2-2 R.DGENYVVLLDSTLPR.S 1737.0 1 19/28
399 staphylococcal nuclease domain-containing protein 1 101996.3 77404397
1 (1 0 0
0 0)
4650, 1-2 R.SSHYDELLAAEAR.A 731.6 1 16/24
400 serine--pyruvate aminotransferase 43009.7 4557289
1 (1 0 0
0 0)
7998, 1-2 R.ESLALIAEQGLENSWR.Q 1053.3 1 18/30
401 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
precursor 40750.3 4758768
1 (1 0 0
0 0)
8007, 2-2 R.LLQYSDALEHLLTTGQGVVLER.S 1103.8 1 28/84
402 malate dehydrogenase, cytoplasmic isoform 2 36425.9 5174539
2 (2 0 0
0 0)
4846, 1-2 K.VIVVGNPANTNCLTASK.S 563.2 1 16/32
5021, 1 K.VIVVGNPANTNCLTASK.S 590.0 1 18/32
403 40S ribosomal protein S3 26688.1 15718687
1 (1 0 0
0 0)
4401, 2-2 R.ELAEDGYSGVEVR.V 2064.0 1 20/24
404 scavenger receptor cysteine-rich type 1 protein M130 isoform a precursor 125450.2
34417911
0
2 (2 0 0
0 0)
6831, 1-2 K.EAEFGQGTGPIWLNEVK.C 869.6 1 16/32
6929, 1 K.EAEFGQGTGPIWLNEVK.C 766.0 1 16/32
405 neutral alpha-glucosidase AB isoform 3 precursor 109437.2 88900491
1 (1 0 0
0 0)
7707, 1 K.VLLVLELQGLQK.N 978.2 1 15/22
406 catechol O-methyltransferase isoform MB-COMT 30036.9 4502969
1 (1 0 0
0 0)
7700, 2-2 R.YLPDTLLLEECGLLR.K 1176.5 1 19/28
407 actin, gamma-enteric smooth muscle isoform 1 precursor 41876.7 4501889
1 (1 0 0
0 0)
5286, 1-2 R.VAPEEHPTLLTEAPLNPK.A 781.0 1 20/34
408 mitochondrial carnitine/acylcarnitine carrier protein 32943.5 4557403
1 (1 0 0
0 0)
4990, 1-2 R.ELIRDEGVTSLYK.G 1289.2 1 18/24
409 transmembrane emp24 domain-containing protein 10 precursor 24975.8 98986464
1 (1 0 0
0 0)
7767, 1-2 R.RLEDLSESIVNDFAYMK.K 1288.5 1 19/32
410 alpha-1-antitrypsin precursor 46736.2 50363217
1 (1 0 0
0 0)
9950, 1 K.ELDRDTVFALVNYIFFK.G 1066.6 1 17/32
411 probable ATP-dependent RNA helicase DDX5 69147.6 4758138
1 (1 0 0
0 0)
5188, 2-2 K.APILIATDVASR.G 1427.5 1 19/22
412 obg-like ATPase 1 isoform 1 44743.2 58761500
1 (1 0 0
0 0)
9036, 1 K.IPAFLNVVDIAGLVK.G 1360.6 1 18/28
413 melanoma inhibitory activity protein 3 precursor 213699.7 12289187 1 (1 0 0
Page 113
0 0 0)
6221, 2-2 R.TQTAISVVEEDLK.L 1131.8 1 17/24
414 mitochondrial import receptor subunit TOM70 67454.4 54607135
1 (1 0 0
0 0)
6698, 1-2 R.CAEGYALYAQALTDQQQFGK.A 556.1 1 16/38
415 malectin precursor 32233.6 7661948
2 (2 0 0
0 0)
6935, 2-2 K.VCALYIMAGTVDDVPK.L 982.2 1 17/30
7162, 1-2 K.VCALYIMAGTVDDVPK.L 1442.3 1 20/30
416 mevalonate kinase 42450.6 4557769
1 (1 0 0
0 0)
6191, 2-2 R.SPALQILLTNTK.V 1371.5 1 17/22
417 ras-related protein Rab-10 22540.8
25622201
9
3 (3 0 0
0 0)
8082, 2-2 K.AFLTLAEDILR.K 880.5 1 15/20
8333, 1-2 K.AFLTLAEDILR.K 1162.0 1 16/20
8444, 1 K.AFLTLAEDILR.K 1030.2 1 16/20
418 4-aminobutyrate aminotransferase, mitochondrial precursor 56438.6 38679946
1 (1 0 0
0 0)
9309, 1 K.NLLLAEVINIIK.R 1735.7 1 18/22
419 core histone macro-H2A.1 isoform 1 39183.2 20336746
1 (1 0 0
0 0)
7178, 1-2 R.HILLAVANDEELNQLLK.G 691.6 1 17/32
420 peroxisomal bifunctional enzyme isoform 1 79494.4 68989263
1 (1 0 0
0 0)
4760, 2-2 R.LHNALALIR.L 898.7 1 15/16
421 uncharacterized protein C8orf74 33768.7 91176323
2 (2 0 0
0 0)
7248, 2-2 R.QIQNTFAILDLK.L 878.9 1 14/22
7467, 1-2 R.QIQNTFAILDLK.L 1100.5 1 15/22
422 E3 ubiquitin-protein ligase MARCH5 31231.5 8923415
1 (1 0 0
0 0)
4385, 2-2 R.IPAEANPLADHVSATR.I 906.0 1 18/30
423 serum paraoxonase/arylesterase 2 isoform 1 39380.6 66529294
1 (1 0 0
0 0)
6154, 1-2 K.LFVYDPNNPPSSEVLR.I 588.3 1 18/30
424 E3 UFM1-protein ligase 1 89594.6 24308039
1 (1 0 0
0 0)
7677, 2-2 K.TYDLPGNFLTQALTQR.L 765.8 1 17/30
425 nuclear pore membrane glycoprotein 210 precursor 205108.8 27477134
1 (1 0 0
0 0)
5963, 1-2 K.AVDPSSVALVTLGSSK.E 911.3 1 19/30
426 alanine aminotransferase 1 54636.6 4885351
1 (1 0 0
0 0)
5134, 1 R.ALCVINPGNPTGQVQTR.E 701.8 1 18/32
427 eukaryotic translation initiation factor 3 subunit A 166568.5 4503509
1 (1 0 0
0 0)
7917, 1 R.FNVLQYVVPEVK.D 2219.1 1 20/22
428 heterogeneous nuclear ribonucleoprotein F 45671.6 4826760
1 (1 0 0
0 0)
7810, 2-2 K.ATENDIYNFFSPLNPVR.V 852.7 1 17/32
429 peroxisomal trans-2-enoyl-CoA reductase 32544.1 19923817
1 (1 0 0
0 0)
Page 114
6407, 1-2 K.ELLELGSNVVIASR.K 521.4 1 14/26
430 long-chain-fatty-acid--CoA ligase 6 isoform d 77670.3
32741232
3
2 (2 0 0
0 0)
5494, 2-2 R.VGFFQGDIR.L 1415.4 1 15/16
5624, 1-2 R.VGFFQGDIR.L 1350.6 1 15/16
431 multidrug resistance-associated protein 6 isoform 1 164872.8
19034302
3
1 (1 0 0
0 0)
4794, 2-2 K.GQVAESGSPAQLLAQK.G 961.7 1 17/30
432 60S ribosomal protein L3 isoform a 46108.6 4506649
1 (1 0 0
0 0)
4778, 1-2 K.AHLMEIQVNGGTVAEK.L 807.5 1 18/30
433 aflatoxin B1 aldehyde reductase member 3 37206.2 41152114
2 (2 0 0
0 0)
7937, 1-2 R.FYAFNPLAGGLLTGK.Y 1102.1 1 19/28
8060, 1 R.FYAFNPLAGGLLTGK.Y 1722.2 1 23/28
434 regulator of microtubule dynamics protein 2 isoform 2 47399.1
28304667
4
1 (1 0 0
0 0)
7672, 1-2 K.FCNLALLLPTVTK.E 963.6 1 15/24
435 annexin A1 38714.0 4502101
1 (1 0 0
0 0)
8370, 1 K.GLGTDEDTLIEILASR.T 610.5 1 16/30
436 beta-2-glycoprotein 1 precursor 38298.0
15326684
1
2 (2 0 0
0 0)
8454, 2-2 K.FICPLTGLWPINTLK.C 704.4 1 16/28
8811, 1 K.FICPLTGLWPINTLK.C 543.1 1 19/28
437 heterogeneous nuclear ribonucleoprotein A3 39594.6 34740329
1 (1 0 0
0 0)
5562, 1 K.IFVGGIKEDTEEYNLR.D 959.9 1 19/30
438 60S ribosomal protein L8 28024.4 15431306
1 (1 0 0
0 0)
3927, 1-2 R.ASGNYATVISHNPETK.K 836.0 1 17/30
439 3 beta-hydroxysteroid dehydrogenase type 7 isoform b 21322.2
21856368
4
1 (1 0 0
0 0)
6792, 1 K.LVYLVTGGCGFLGEHVVR.M 683.8 1 19/34
440 transmembrane emp24 domain-containing protein 2 precursor 22761.1 5803149
1 (1 0 0
0 0)
7366, 1-2 K.IVMFTIDIGEAPK.G 1219.3 1 16/24
441 eukaryotic translation initiation factor 3 subunit L isoform 1 66726.6 7705433
1 (1 0 0
0 0)
5278, 1-2 K.VFSDEVQQQAQLSTIR.S 606.8 1 17/30
442 beta-soluble NSF attachment protein 33556.8 44917606
1 (1 0 0
0 0)
8136, 1-2 R.LDQWLTTMLLR.I 1297.5 1 16/20
443 vesicle-associated membrane protein-associated protein B/C isoform 1 27228.2 4759302
1 (1 0 0
0 0)
4938, 2-2 K.VEQVLSLEPQHELK.F 881.4 1 17/26
444 GTP-binding protein SAR1a 22366.6
21741636
9
2 (2 0 0
0 0)
6165, 2-2 K.LVFLGLDNAGK.T 1284.5 1 18/20
6321, 1-2 K.LVFLGLDNAGK.T 1244.1 1 18/20
445 26S proteasome non-ATPase regulatory subunit 5 56195.4 4826952
1 (1 0 0
0 0)
Page 115
5538, 2-2 K.VFTAIANQPWAQK.L 1405.6 1 18/24
446 vesicle transport protein GOT1B 15425.6 7705636
1 (1 0 0
0 0)
8048, 2-2 R.VPVLGSLLNLPGIR.S 1821.4 1 19/26
447 cadherin-1 preproprotein 97455.4 4757960
1 (1 0 0
0 0)
6699, 1-2 R.DTANWLEINPDTGAISTR.A 762.5 1 17/34
448 UDP-glucuronosyltransferase 2B11 precursor 61037.9 4507823
2 (2 0 0
0 0)
4192, 2-2 R.FDGNKPDALGLNTR.L 632.0 1 18/26
4288, 1-2 R.FDGNKPDALGLNTR.L 584.7 1 18/26
449 60S ribosomal protein L23 14865.4 4506605
1 (1 0 0
0 0)
6774, 2-2 R.ISLGLPVGAVINCADNTGAK.N 576.3 1 18/38
450 beta,beta-carotene 9',10'-oxygenase isoform a 65673.7 82617624
1 (1 0 0
0 0)
7236, 1 R.NYIIFIEQPLK.M 1473.4 2 16/20
451 3-ketoacyl-CoA thiolase, mitochondrial 41923.9
16761448
5
1 (1 0 0
0 0)
6131, 2-2 K.DFTATDLSEFAAK.A 1825.9 1 19/24
452 glycerol-3-phosphate acyltransferase 1, mitochondrial precursor 93794.2
19035853
9
2 (2 0 0
0 0)
7259, 2-2 R.LIANLAEHILFTASK.S 691.3 1 13/28
7488, 1-2 R.LIANLAEHILFTASK.S 558.9 1 13/28
453 histone H2B type 1-O 13906.0 16306566
2 (2 0 0
0 0)
4408, 2-2 R.KESYSIYVYK.V 764.9 1 14/18
4504, 1-2 R.KESYSIYVYK.V 1158.9 1 16/18
454 N-terminal kinase-like protein isoform A 89630.9
11543024
1
1 (1 0 0
0 0)
4916, 2-2 K.LESVSEDPTQLEEVEK.D 743.5 1 17/30
455 aminopeptidase N precursor 109538.8
15726630
0
1 (1 0 0
0 0)
5956, 1 R.AQIINDAFNLASAHK.V 1180.9 1 19/28
456 heat shock-related 70 kDa protein 2 70020.5 13676857
1 (1 0 0
0 0)
3796, 1-2 K.STAGDTHLGGEDFDNR.M 1164.2 1 19/30
457 protein MON2 homolog 190356.9
11432655
2
1 (1 0 0
0 0)
7050, 2-2 R.AWDVLLDHIQSAALSK.N 820.8 1 15/30
458 peripherin 53650.5 21264345
1 (1 0 0
0 0)
5248, 1-2 K.NLQEAEEWYK.S 970.9 1 14/18
459 mannosyl-oligosaccharide glucosidase isoform 1 91917.0
14999960
6
2 (2 0 0
0 0)
7511, 2-2 R.LGPLLDILADSR.H 1392.0 1 18/22
7758, 1-2 R.LGPLLDILADSR.H 1367.5 1 17/22
460 mitochondrial glutamate carrier 1 34470.0 13375983
2 (2 0 0
0 0)
5483, 1-2 R.GVNEDTYSGILDCAR.K 857.0 1 18/28
5603, 1 R.GVNEDTYSGILDCAR.K 909.9 1 18/28
461 ras-related protein Rab-18 22976.9 10880989
2 (2 0 0
0 0)
Page 116
7395, 2-2 K.LDNWLNELETYCTR.N 816.9 1 15/26
7661, 1-2 K.LDNWLNELETYCTR.N 1002.1 1 15/26
462 neutral cholesterol ester hydrolase 1 isoform c 31167.6
22642395
0
1 (1 0 0
0 0)
7859, 2-2 R.SAPLIADQAVLQLLPK.T 742.0 1 20/30
463 14-3-3 protein epsilon 29173.7 5803225
1 (1 0 0
0 0)
7452, 2-2 K.LICCDILDVLDK.H 886.5 1 16/22
464 ADP-ribosylation factor 6 20082.0 4502211
2 (2 0 0
0 0)
7053, 2-2 R.DAIILIFANK.Q 1437.9 1 15/18
7276, 1-2 R.DAIILIFANK.Q 1608.5 1 15/18
465 sodium-coupled neutral amino acid transporter 3 55772.8 5870893
1 (1 0 0
0 0)
9548, 1 K.SELPLVIQTFLNLEEK.T 763.3 1 16/30
466 F-actin-capping protein subunit beta isoform 2 31350.3
33086467
9
2 (2 0 0
0 0)
5344, 1-2 K.GCWDSIHVVEVQEK.S 657.7 1 19/26
5478, 1 K.GCWDSIHVVEVQEK.S 562.7 1 17/26
467 catenin delta-1 isoform 2A 98048.4
33268822
2
1 (1 0 0
0 0)
6736, 1 K.ALSAIADLLTNEHER.V 1033.7 1 19/28
468 tyrosine aminotransferase 50399.2 4507369
1 (1 0 0
0 0)
5015, 1-2 R.EEIASYYHCPEAPLEAK.D 562.7 1 14/32
469 ras-related protein Rab-1A isoform 1 22677.6 4758988
1 (1 0 0
0 0)
7854, 1-2 K.NATNVEQSFMTMAAEIK.K 833.7 1 18/32
470 poly(rC)-binding protein 1 37497.6
22235215
1
1 (1 0 0
0 0)
6686, 1-2 R.IITLTGPTNAIFK.A 800.1 1 17/24
471 clarin-3 25321.2 22748685
1 (1 0 0
0 0)
6942, 1-2 K.FAVLEILNNSSQK.T 988.9 1 17/24
472 peroxiredoxin-4 precursor 30539.7 5453549
1 (1 0 0
0 0)
5386, 1 K.DYGVYLEDSGHTLR.G 1120.0 1 18/26
473 transmembrane 9 superfamily member 1 isoform b precursor 55250.5 62460635
1 (1 0 0
0 0)
6204, 2-2 K.SLSLGEVLDGDR.M 1356.5 1 17/22
474 asialoglycoprotein receptor 2 isoform a 35191.1 4502253
1 (1 0 0
0 0)
5060, 2-2 K.ADHDALLFHLK.H 1251.0 1 16/20
475 spectrin beta chain, brain 2 271291.8 5902122
1 (1 0 0
0 0)
6412, 1 R.VQAVDAVAAELAAER.Y 1413.7 1 18/28
476 proteasome inhibitor PI31 subunit 29816.5
14561142
6
1 (1 0 0
0 0)
5801, 1 R.IVSGIITPIHEQWEK.A 504.3 1 16/28
477 rab GDP dissociation inhibitor beta isoform 1 50662.9 6598323
1 (1 0 0
0 0)
9516, 1 K.VPSTEAEALASSLMGLFEK.R 521.2 1 14/36
Page 117
478 enoyl-CoA hydratase domain-containing protein 1 isoform 1 32997.0
15769451
6
2 (1 1 0
0 0)
6360, 2-2 R.ELYLEEALQNER.D 536.4 3 13/22
6542, 1-2 R.ELYLEEALQNER.D 1079.0 2 15/22
479 glutathione S-transferase A3 25301.5 24430144
2 (2 0 0
0 0)
7203, 1-2 R.WLLAAAGVEFEEK.F 1174.4 1 19/24
7224, 1-2 R.WLLAAAGVEFEEK.F 1701.3 1 18/24
480 oligosaccharyltransferase complex subunit OSTC 16829.2 24308271
2 (2 0 0
0 0)
6888, 2-2 R.VPFLVLECPNLK.L 1137.2 1 17/22
7234, 1 R.VPFLVLECPNLK.L 1236.7 1 17/22
481 patatin-like phospholipase domain-containing protein 3 52865.1 17196626
1 (1 0 0
0 0)
9020, 1 R.LSILPWDESILDTLSPR.L 581.3 1 17/32
482 cutaneous T-cell lymphoma-associated antigen 9 87952.4
22458677
3
1 (1 0 0
0 0)
6762, 2-2 R.SNSELEDEILCLEK.D 1268.1 1 17/26
483 inositol 1,4,5-trisphosphate receptor type 2 308061.1 95147335
1 (1 0 0
0 0)
6543, 2-2 K.DVGHNIYILAHQLAR.H 925.8 1 16/28
484 26S protease regulatory subunit 10B 45796.7
19553939
5
2 (2 0 0
0 0)
7494, 2-2 K.ALQSVGQIVGEVLK.Q 782.9 1 15/26
7745, 1-2 K.ALQSVGQIVGEVLK.Q 565.5 1 15/26
485 protein LYRIC 63836.5
22355591
7
1 (1 0 0
0 0)
3954, 2-2 K.NKGDSHLNVQVSNFK.S 538.9 1 13/28
486 HCLS1-binding protein 3 42780.0 68800430
1 (1 0 0
0 0)
8273, 1 K.DAELAGSPELLEFLGTR.S 673.2 1 19/32
487 cytochrome P450 3A43 isoform 2 57669.5 16933533
2 (2 0 0
0 0)
5192, 2-2 K.LQEEIDAVLPNK.A 1339.6 1 16/22
5480, 1 K.LQEEIDAVLPNK.A 1638.6 1 18/22
488 ATP synthase subunit gamma, mitochondrial isoform H (heart) precursor 32880.7 4885079
1 (1 0 0
0 0)
6599, 2-2 R.IYGLGSLALYEK.A 1586.7 1 19/22
489 galectin-4 35940.9 5453712
1 (1 0 0
0 0)
4392, 2-2 K.VGSSGDIALHINPR.M 1220.3 1 19/26
490 ras-related protein Rab-2B isoform 1 24214.2 21361884
1 (1 0 0
0 0)
5856, 1-2 K.SCLLLQFTDKR.F 1446.0 1 17/20
491 dual specificity mitogen-activated protein kinase kinase 4 44287.5 4506889
1 (1 0 0
0 0)
7200, 1-2 K.LCDFGISGQLVDSIAK.T 681.7 1 16/30
492 PREDICTED: POTE ankyrin domain family member I isoform 2 121281.5 88953571
1 (1 0 0
0 0)
4656, 1-2 K.IWHHTFYNELR.V 1107.1 1 16/20
493 galactokinase 42272.0 4503895 1 (1 0 0
Page 118
0 0)
5894, 1-2 R.SLETSLVPLSDPK.L 608.7 1 15/24
494 60S acidic ribosomal protein P0 34273.3 16933546
1 (1 0 0
0 0)
7554, 1 R.VLALSVETDYTFPLAEK.V 825.7 1 18/32
495 fibrinogen alpha chain isoform alpha-E preproprotein 94972.5 4503689
1 (1 0 0
0 0)
6251, 1 K.GLIDEVNQDFTNR.I 1301.6 1 19/24
496 thromboxane-A synthase isoform 1 60649.2
19597289
8
1 (1 0 0
0 0)
5885, 2-2 K.QVLVENFSNFTNR.M 768.0 1 15/24
497 pyruvate carboxylase, mitochondrial precursor 129632.7
10604929
2
1 (1 0 0
0 0)
9225, 1 K.YSLQYYMGLAEELVR.A 1002.9 1 18/28
498 vacuolar protein sorting-associated protein VTA1 homolog 33879.0 21361741
1 (1 0 0
0 0)
6460, 1 K.YAGSALQYEDVSTAVQNLQK.A 925.5 1 18/38
499 apolipoprotein O-like precursor 29158.7
11681261
0
1 (1 0 0
0 0)
7562, 2-2 K.MGVITVSGLAGLVSAR.K 800.1 1 16/30
500 perilipin-5 50791.1
11629217
2
1 (1 0 0
0 0)
4502, 1-2 R.SSVWEQDQQNVVQR.V 1451.6 1 17/26
501 signal recognition particle receptor subunit beta 29702.0
28479526
6
1 (1 0 0
0 0)
4178, 1-2 R.SAAPSTLDSSSTAPAQLGK.K 911.1 1 21/36
502 heterogeneous nuclear ribonucleoprotein C-like 1 32142.2 61966711
1 (1 0 0
0 0)
6760, 1 R.VFIGNLNTLVVK.K 1120.0 1 17/22
503 plastin-3 isoform 1 70810.6 7549809
1 (1 0 0
0 0)
5212, 1-2 R.QFVTPADVVSGNPK.L 597.2 1 15/26
504 cAMP-dependent protein kinase catalytic subunit alpha isoform 1 40589.3 4506055
1 (1 0 0
0 0)
7950, 1 R.ILQAVNFPFLVK.L 1445.0 1 17/22
505 acyl-CoA dehydrogenase family member 11 87263.9 38505218
1 (1 0 0
0 0)
5254, 2-2 R.VPATNLILGEGR.G 962.3 1 16/22
506 dynamin-2 isoform 5 97976.6
29975839
4
1 (1 0 0
0 0)
5454, 1 K.VPVGDQPPDIEYQIK.D 682.7 1 19/28
507 ras GTPase-activating-like protein IQGAP1 189250.1 4506787
1 (1 0 0
0 0)
6746, 1-2 R.EQLWLANEGLITR.L 825.0 1 14/24
508 guanine nucleotide-binding protein subunit alpha-12 44278.9 42476111
2 (2 0 0
0 0)
5268, 2-2 K.ILLLGAGESGK.S 1077.1 1 16/20
5398, 1-2 K.ILLLGAGESGK.S 933.4 1 16/20
509 APOBEC1 complementation factor isoform 1 64256.0 20357572
1 (1 0 0
0 0)
6174, 1 K.VTEGVVDVIVYPSAADK.T 560.0 3 15/32
510 ribonuclease inhibitor 49973.3 42822872 1 (1 0 0
Page 119
0 0)
7518, 1-2 R.TLWIWECGITAK.G 564.1 1 12/22
511 vitamin K-dependent gamma-carboxylase isoform 1 87560.4 21361163
1 (1 0 0
0 0)
8714, 1 K.LLGFEWTDLSSWR.R 776.9 1 15/24
512 guanine nucleotide-binding protein G(i) subunit alpha-1 40360.8 33946324
1 (1 0 0
0 0)
8978, 1 K.AVVYSNTIQSIIAIIR.A 537.3 1 15/30
513 cytoskeleton-associated protein 4 66022.0 19920317
2 (2 0 0
0 0)
8267, 2-2 K.VQSLQATFGTFESILR.S 600.6 1 13/30
8531, 1-2 K.VQSLQATFGTFESILR.S 539.0 1 12/30
514 beta-actin-like protein 2 42002.9 63055057
1 (1 0 0
0 0)
6195, 1-2 R.DLTDYLMK.I 863.1 1 11/14
515 ranBP2-like and GRIP domain-containing protein 4 197286.6
21105943
1
1 (1 0 0
0 0)
6764, 1-2 K.SGQSALYDALFSSQSPK.D 564.4 1 15/32
516 DCC-interacting protein 13-alpha 79663.1 6912242
1 (1 0 0
0 0)
7466, 1-2 K.SETEDSILHQLFIVR.F 697.1 1 15/28
517 leukotriene-B(4) omega-hydroxylase 2 isoform a 59846.4
11922056
2
2 (2 0 0
0 0)
6808, 2-2 K.VVLGLTLLR.F 728.9 1 14/16
7026, 1-2 K.VVLGLTLLR.F 761.4 1 14/16
518 UDP-glucose:glycoprotein glucosyltransferase 1 precursor 177187.7 9910280
1 (1 0 0
0 0)
9010, 1 R.ILASPVELALVVMK.D 739.0 1 16/26
519 HLA class I histocompatibility antigen, A-1 alpha chain precursor 40840.5 24797067
1 (1 0 0
0 0)
6344, 2-2 R.FIAVGYVDDTQFVR.F 717.0 1 17/26
520 leukotriene-B(4) omega-hydroxylase 2 isoform b 59738.4
31283683
3
1 (1 0 0
0 0)
7774, 2-2 K.VWMGPIFPVIR.F 1309.5 1 16/20
521 lipopolysaccharide-responsive and beige-like anchor protein isoform 2 319105.2
14823359
6
1 (1 0 0
0 0)
7516, 1-2 K.NAGLAFIELVNEGR.L 849.5 1 12/26
522 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor 31629.6
11538709
4
1 (1 0 0
0 0)
6159, 2-2 K.LQDPFSLYR.C 558.6 2 13/16
523 gamma-glutamyl hydrolase precursor 35964.1 4503987
1 (1 0 0
0 0)
8764, 1 K.TAFYLAEFFVNEAR.K 1096.5 1 19/26
524 AP-3 complex subunit beta-1 121319.4 32484979
1 (1 0 0
0 0)
7464, 1 K.LLTQYILNLGK.Y 874.0 1 14/20
525 coatomer subunit delta isoform 1 57210.1 11863154
1 (1 0 0
0 0)
7700, 1-2 K.NSNILEDLETLR.L 1059.6 1 17/22
526 lanosterol 14-alpha demethylase isoform 1 precursor 57278.0 4503243
1 (1 0 0
0 0)
Page 120
8776, 2-2 K.IDDILQTLLDATYK.D 736.5 1 15/26
527 DNA damage-binding protein 1 126967.0
14852901
4
1 (1 0 0
0 0)
6045, 1-2 R.ALYYLQIHPQELR.Q 599.1 1 15/24
528 EH domain-containing protein 1 60626.4 30240932
1 (1 0 0
0 0)
7653, 1-2 R.VYIGSFWSHPLLIPDNR.K 603.8 1 14/32
529 exocyst complex component 5 81852.4 5730037
1 (1 0 0
0 0)
6244, 1-2 K.LHLIAQELPFDR.F 703.6 1 15/22
530 tubulin alpha-1C chain 49895.0 14389309
1 (1 0 0
0 0)
6894, 1-2 R.AVCMLSNTTAVAEAWAR.L 644.3 2 15/32
531 complement factor B preproprotein 85532.4 67782358
1 (1 0 0
0 0)
5212, 1 R.FLCTGGVSPYADPNTCR.G 635.8 1 16/32
532 serotransferrin precursor 77049.5 4557871
1 (1 0 0
0 0)
3398, 1-2 R.KPVEEYANCHLAR.A 961.1 1 18/24
533 histone
H1.0 20862.8 4885371
1 (1 0 0
0 0)
6135, 2-2 K.YSDMIVAAIQAEK.N 745.6 2 15/24
534 torsin-1A-interacting protein 1 66248.0 39753957
1 (1 0 0
0 0)
6683, 1-2 R.SQPAILLLTAAR.D 855.2 1 16/22
535 solute carrier organic anion transporter family member 3A1 isoform 2 74372.1
22283157
3
1 (1 0 0
0 0)
6995, 1-2 K.PGGSSGGGRSGELQGDEAQR.N 918.0 1 18/38
536 sterol 26-hydroxylase, mitochondrial precursor 60234.4 4503211
1 (1 0 0
0 0)
5595, 2-2 K.VGLQFLQR.Q 996.8 1 13/14
537 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
precursor 42509.3 6681764
2 (2 0 0
0 0)
8207, 1-2 R.VFEISPFEPWITR.D 828.2 1 15/24
8318, 1 R.VFEISPFEPWITR.D 995.2 1 17/24
538 mitochondrial import receptor subunit TOM40 homolog 37892.8 5174723
1 (1 0 0
0 0)
5670, 1 K.FVNWQVDGEYR.G 950.2 1 15/20
539 6-phosphofructokinase, liver type 85017.9 48762920
1 (1 0 0
0 0)
8660, 1 R.SEWGSLLEELVAEGK.I 1180.8 1 19/28
540 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
isoform 1 72207.9 4826894
1 (1 0 0
0 0)
5622, 1-2 K.TALQQPEAIEKPK.A 794.6 3 13/24
541 heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2 36005.7 4504447
1 (1 0 0
0 0)
7671, 1 K.LFIGGLSFETTEESLR.N 1095.6 1 22/30
542 ras-related protein Rap-1A 20987.1 4506413
1 (1 0 0
0 0)
5310, 2-2 R.QWCNCAFLESSAK.S 517.2 1 12/24
543 metal transporter CNNM2 isoform 3 60487.1 40068051
1 (1 0 0
0 0)
Page 121
7210, 1 K.MAGGQAAAALPTWKMAARR.S 754.5 1 18/36
544 ras-related protein Rab-15 23517.8 38371739
1 (1 0 0
0 0)
5244, 1-2 R.IQIWDTAGQER.Y 882.1 1 15/20
545 alpha-2-macroglobulin precursor 163290.5 66932947
1 (1 0 0
0 0)
6628, 1 R.IAQWQSFQLEGGLK.Q 992.5 1 15/26
546 apolipoprotein L2 37092.1 13562090
1 (1 0 0
0 0)
3953, 1-2 R.ALAEEVEQVHR.G 1633.9 1 16/20
547 fatty acid-binding protein, liver 14208.3 4557577
2 (2 0 0
0 0)
5963, 2-2 K.AIGLPEELIQK.G 541.6 1 16/20
6110, 1-2 K.AIGLPEELIQK.G 529.9 1 16/20
548 protein DJ-1 19890.9 31543380
1 (1 0 0
0 0)
4720, 1-2 R.DVVICPDASLEDAKK.E 630.1 1 15/28
549 dynamin-like 120 kDa protein, mitochondrial isoform 1 111629.9
22483124
3
1 (1 0 0
0 0)
7446, 2-2 K.AKNEILDEVISLSQVTPK.H 773.0 1 18/34
550 alkylglycerol monooxygenase 51499.6 51972212
1 (1 0 0
0 0)
6762, 1-2 R.LDDALTSISAGVLSR.L 723.9 2 14/28
551 transmembrane protein 109 precursor 26209.8 13129092
2 (1 1 0
0 0)
6191, 2-2 R.EAPVDVLTQIGR.S 894.8 2 15/22
6346, 1-2 R.EAPVDVLTQIGR.S 763.8 2 14/22
552 erlin-1 39170.9
15480048
7
2 (2 0 0
0 0)
3941, 2-2 R.SVQTTLQTDEVK.N 951.9 1 15/22
4022, 1-2 R.SVQTTLQTDEVK.N 937.5 1 15/22
553 asialoglycoprotein receptor 1 isoform b 29143.8
30838736
3
1 (1 0 0
0 0)
6464, 2-2 R.WVCETELDKASQEPPLL.- 553.1 1 17/32
554 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 50878.0
16785777
8
1 (1 0 0
0 0)
7768, 1 R.GLLQQIGDALSSQR.G 550.0 1 13/26
555 lysosome-associated membrane glycoprotein 1 precursor 44882.1
11238062
8
1 (1 0 0
0 0)
8393, 1-2 R.FFLQGIQLNTILPDAR.D 555.8 1 13/30
556 MAP kinase-activating death domain protein isoform g 175915.5 18860873
1 (1 0 0
0 0)
7811, 2-2 R.VYLYEGLLGR.D 954.1 1 13/18
557 calpain-2 catalytic subunit isoform 2 71475.3
22570310
0
1 (1 0 0
0 0)
4721, 1-2 K.KPPPNLFKIIQK.A 582.2 4 13/22
558 calreticulin precursor 48141.1 4757900
1 (1 0 0
0 0)
6876, 2-2 R.FYALSASFEPFSNK.G 822.2 1 14/26
559 15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 28977.1 31542939
1 (1 0 0
0 0)
4562, 2-2 K.VALVTGAAQGIGR.A 1153.6 1 17/24
Page 122
560 insulin receptor-related protein precursor 143719.0 31657140
1 (1 0 0
0 0)
5132, 1 R.DLFPNLAVIRGTR.L 525.8 4 13/24
561 splicing factor 3B subunit 1 isoform 1 145829.1 54112117
1 (1 0 0
0 0)
8670, 1 K.AIGPHDVLATLLNNLK.V 984.1 1 17/30
562 thioredoxin-related transmembrane protein 1 precursor 31791.0
15110129
2
1 (1 0 0
0 0)
6958, 2-2 K.DFINFISDKEWK.S 530.0 4 12/22
563 ADP-ribosylation factor GTPase-activating protein 2 isoform 1 56720.0 31543983
1 (1 0 0
0 0)
7905, 1-2 R.STELDSNWNWFQLR.C 506.4 1 11/26
564 ATP-binding cassette sub-family F member 1 isoform a 95925.1 69354671
1 (1 0 0
0 0)
6544, 1 K.IGFFNQQYAEQLR.M 523.3 1 12/24
565 histone
H3.1 15404.0 4504281
1 (1 0 0
0 0)
4478, 2-2 R.EIAQDFKTDLR.F 759.8 1 15/20
566 splicing factor, proline- and glutamine-rich 76148.9 4826998
1 (1 0 0
0 0)
3864, 1-2 R.FATHAAALSVR.N 1187.3 1 17/20
567 probable G-protein coupled receptor 110 isoform 1 precursor 101363.9 61743940
1 (1 0 0
0 0)
5547, 1-2 K.QNSSDLSAKPK.F 1077.2 1 15/20
568 serine/threonine-protein kinase OSR1 58021.8 4826878
2 (2 0 0
0 0)
7100, 2-2 K.SGVLDESTIATILR.E 557.5 1 16/26
7318, 1-2 K.SGVLDESTIATILR.E 794.0 1 14/26
569 NADH-cytochrome b5 reductase 1 34094.6 49574502
1 (1 0 0
0 0)
8056, 2-2 K.LGMIAGGTGITPMLQLIR.A 511.4 1 14/34
570 40S ribosomal protein S2 31324.2 15055539
1 (1 0 0
0 0)
8187, 2-2 K.SLEEIYLFSLPIK.E 1419.2 1 17/24
571 hemoglobin subunit epsilon 16202.7 4885393
3 (3 0 0
0 0)
6782, 1-2 R.LLVVYPWTQR.F 1113.0 1 15/18
6902, 1 R.LLVVYPWTQR.F 1135.5 1 15/18
12029, 1 R.LLVVYPWTQR.F 737.0 1 13/18
572 zinc finger protein 175 81609.1 6005970
1 (1 0 0
0 0)
9164, 1 K.ECGKVFIQRSELLTHQK.T 811.3 1 17/32
573 proteasome activator complex subunit 2 27401.4 30410792
1 (1 0 0
0 0)
3843, 2-2 R.ALVHERDEAAYGELR.A 558.2 1 14/28
574 RPS10-NUDT3 protein 33140.6
32111708
4
1 (1 0 0
0 0)
7979, 2-2 R.IAIYELLFK.E 833.7 1 13/16
575 3-keto-steroid reductase 38205.9 7705421
2 (2 0 0
0 0)
8013, 2-2 K.ALFFGLFSR.K 720.2 1 12/16
8271, 1-2 K.ALFFGLFSR.K 731.0 1 12/16
576 rho-related GTP-binding protein RhoB precursor 22123.3 4757764 2 (2 0 0
Page 123
0 0)
6510, 2-2 K.QVELALWDTAGQEDYDR.L 522.7 1 13/32
6672, 1-2 K.QVELALWDTAGQEDYDR.L 693.0 1 16/32
577 atlastin-3 60541.6 45827806
1 (1 0 0
0 0)
3776, 2-2 K.IYQGEDLPHPK.S 1108.9 1 15/20
578 bax inhibitor 1 isoform 1 26537.6
14874620
9
1 (1 0 0
0 0)
5727, 2-2 R.KINFDALLK.F 725.3 1 12/16
579 type I iodothyronine deiodinase isoform a 28774.2 4557522
1 (1 0 0
0 0)
4806, 2-2 R.LQAAHLLLAR.S 1063.4 1 15/18
580 dual specificity mitogen-activated protein kinase kinase 1 43438.8 5579478
1 (1 0 0
0 0)
8200, 1 K.LPSGVFSLEFQDFVNK.C 527.7 1 17/30
581 signal recognition particle receptor subunit alpha isoform 1 69810.8 23308697
1 (1 0 0
0 0)
7805, 1-2 K.DAAGIAMEAIAFAR.N 759.1 1 14/26
582 serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 1 32004.2
28160413
6
1 (1 0 0
0 0)
11042, 2-2 R.VALRTLGDTGFM*PPDKITR.S 675.1 1 15/36
583 acid ceramidase isoform b 46503.3
18901154
6
1 (1 0 0
0 0)
5128, 2-2 R.WYVVQTNYDR.W 723.3 1 13/18
584 signal recognition particle 68 kDa protein 70729.2 24497620
1 (1 0 0
0 0)
7798, 1 K.DLPDVQELITQVR.S 904.4 1 17/24
585 protocadherin-10 isoform 1 precursor 112935.2 14589916
1 (1 0 0
0 0)
5555, 1-2 R.KELDGLLTNTR.A 1332.4 1 16/20
586 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 12496.6 4503253
1 (1 0 0
0 0)
5445, 2-2 R.FLEEYLSSTPQR.L 705.7 1 15/22
587 prostaglandin reductase 1 isoform 2 32894.9
22605613
0
1 (1 0 0
0 0)
5550, 1 K.HFVGYPTNSDFELK.T 856.9 1 17/26
588 beta-glucuronidase precursor 74731.4
26883419
2
1 (1 0 0
0 0)
5897, 1 K.SLLEQYHLGLDQK.R 548.1 2 15/24
589 G patch domain-containing protein 3 59337.6
20527745
8
1 (1 0 0
0 0)
7080, 1-2 K.AENEAFTLADLK.Q 542.2 1 12/22
590 phosphoinositide 3-kinase adapter protein 1 90397.3 45505139
1 (1 0 0
0 0)
6546, 2-2 R.DEELPTLLHFAAK.Y 592.0 1 16/24
591 heat shock cognate 71 kDa protein isoform 2 53517.3 24234686
1 (1 0 0
0 0)
5894, 2-2 K.DAGTIAGLNVLR.I 838.4 3 15/22
592 brefeldin A-inhibited guanine nucleotide-exchange protein 2 202036.4
15041798
6
1 (1 0 0
0 0)
7026, 2-2 K.VGCNPNEDVAIFAVDSLR.Q 566.7 1 14/34
Page 124
593 AP-1 complex subunit gamma-1 isoform b 91351.0 71772942
1 (1 0 0
0 0)
7704, 1-2 K.ELLYFLDSCEPEFK.A 530.9 1 13/26
594 peroxiredoxin-1 22110.2 4505591
1 (1 0 0
0 0)
4876, 1-2 R.TIAQDYGVLK.A 594.3 1 15/18
595 5'-AMP-activated protein kinase subunit beta-2 30302.0 4885561
1 (1 0 0
0 0)
6101, 1-2 K.KSDFEVFDALK.L 1257.5 1 15/20
596 phosphorylase b kinase regulatory subunit beta isoform a 124883.5 4505783
1 (1 0 0
0 0)
8916, 1 R.FNPILDMLAALKK.G 640.4 1 15/24
597 nitric oxide synthase, brain isoform 3 125112.6
32363543
1
1 (1 0 0
0 0)
9963, 2-2 -.MGSIMHPSQHARRPEDVR.T 508.8 1 14/34
598 stomatin-like protein 2 38533.8 7305503
1 (1 0 0
0 0)
5121, 2-2 K.AEQINQAAGEASAVLAK.A 525.4 1 17/32
599 uncharacterized protein LOC728392 12843.6
24084932
9
1 (1 0 0
0 0)
6332, 2-2 R.AGGRAQGGRAGQPPK.A 808.8 2 16/28
600 mast cell carboxypeptidase A precursor 48669.6
22131674
9
1 (1 0 0
0 0)
7481, 2-2 K.PTCRETMLAVK.F 723.7 3 13/20
601 tubulin alpha-4A chain 49924.1 17921989
1 (1 0 0
0 0)
7428, 2-2 R.AVFVDLEPTVIDEIR.N 641.5 1 15/28
602 rho GTPase-activating protein 1 50435.4 4757766
1 (1 0 0
0 0)
6060, 1 K.NPEQEPIPIVLR.E 642.5 1 16/22
603 transcriptional adapter 2-alpha isoform a 51505.6 68509270
1 (1 0 0
0 0)
6602, 1-2 K.FIESHALEFELRR.E 760.2 1 14/24
604 heterogeneous nuclear ribonucleoprotein M isoform a 77515.2 14141152
1 (1 0 0
0 0)
5982, 1-2 K.LKEVFSMAGVVVR.A 1242.5 1 17/24
605 UPF0554 protein C2orf43 37318.3 11345458
1 (1 0 0
0 0)
7536, 2-2 R.AFLLFPTIER.M 536.7 2 13/18
606 AP-2 complex subunit alpha-2 isoform 1 104088.9
33882768
5
1 (1 0 0
0 0)
5312, 1-2 K.THIETVINALK.T 986.4 1 15/20
607 heat shock 70 kDa protein 1-like 70374.6
12425649
6
2 (2 0 0
0 0)
4828, 2-2 K.AKIHDIVLVGGSTR.I 956.3 1 16/26
4961, 1-2 K.AKIHDIVLVGGSTR.I 706.7 1 16/26
608 X-ray repair cross-complementing protein 5 82704.0 10863945
1 (1 0 0
0 0)
6534, 1-2 K.SQLDIIIHSLK.K 549.6 2 13/20
609 heat shock protein beta-1 22782.3 4504517
1 (1 0 0
0 0)
6561, 1 R.LFDQAFGLPR.L 1314.6 1 16/18
610 enoyl-CoA delta isomerase 2, mitochondrial isoform 1 40182.8 45643119 1 (1 0 0
Page 125
0 0)
7868, 1-2 R.WLSDECTNAVVNFLSR.K 574.8 1 15/30
611 ras-related protein Rap-1b isoform 4 15355.6
35445935
6
1 (1 0 0
0 0)
4215, 2-2 K.YDPTIEDSYR.K 526.5 1 15/18
612 prolargin precursor 43809.6 4506041
1 (1 0 0
0 0)
6892, 1 K.LENLLLLDLQHNR.L 712.6 1 13/24
613 glutathione S-transferase A5 25721.8 24308514
1 (1 0 0
0 0)
5235, 1-2 R.AILNYIASK.Y 771.2 1 15/16
614 WASH complex subunit strumpellin 134285.3
12095285
1
1 (1 0 0
0 0)
7268, 1-2 K.DQILTDSRYNPR.I 583.1 2 14/22
615 ADP/ATP translocase 1 33064.2 55749577
1 (1 0 0
0 0)
7610, 1 R.YFPTQALNFAFK.D 612.7 1 17/22
616 vacuolar protein sorting-associated protein 13A isoform C 355859.0 66346672
1 (1 0 0
0 0)
6953, 2-2 K.TATGLLYIIETQK.V 677.3 1 13/24
617 cytochrome c oxidase subunit 7A2, mitochondrial precursor 12843.9
26211822
7
1 (1 0 0
0 0)
5356, 2-2 K.GGVADALLYR.A 856.4 1 13/18
618 squalene monooxygenase 63922.8 62865635
1 (1 0 0
0 0)
7262, 1 K.ELHAPLTVVADGLFSK.F 565.3 1 17/30
619 60S ribosomal protein L30 12784.0 4506631
1 (1 0 0
0 0)
5679, 1 K.LVILANNCPALR.K 594.3 1 15/22
620 polypeptide N-acetylgalactosaminyltransferase 2 precursor 64732.4 4758412
1 (1 0 0
0 0)
7506, 2-2 K.GGFDWNLVFK.W 776.1 2 12/18
621 serpin H1 precursor 46440.3
33336085
1
1 (1 0 0
0 0)
6844, 1-2 R.LYGPSSVSFADDFVR.S 689.4 1 15/28
622 alpha-tocopherol transfer protein 31749.4 4507723
1 (1 0 0
0 0)
4161, 2-2 R.AECPEISADLHPR.S 638.7 1 14/24
623 translocon-associated protein subunit alpha precursor 32235.1
16940400
9
1 (1 0 0
0 0)
7808, 2-2 K.GTEDFIVESLDASFR.Y 739.7 1 17/28
624 mitochondrial ribonuclease P protein 3 precursor 67315.0 62988276
1 (1 0 0
0 0)
8243, 1 R.ESQLLLNVVSQLAK.R 723.3 1 14/26
625 bcl-2-like protein 13 52722.8 45243501
1 (1 0 0
0 0)
7274, 1-2 K.ALQMLLSQPVTYQAFR.E 630.3 1 14/30
626 transmembrane emp24 domain-containing protein 5 isoform 1 precursor 26004.7
28216581
4
1 (1 0 0
0 0)
7155, 1-2 K.LEDILESINSIK.S 690.5 3 13/22
627 probable N-acetyltransferase 8 25618.9
11719051
7
1 (1 0 0
0 0)
Page 126
6460, 2-2 R.QWVVGLLSR.G 801.8 1 13/16
628 serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform 4 101006.2
33927604
4
1 (1 0 0
0 0)
4481, 1-2 R.GPVQTHISEVIR.G 718.7 1 14/22
629 protein kinase C alpha type 76763.6 4506067
1 (1 0 0
0 0)
3765, 1-2 K.AEVADEKLHVTVR.D 505.1 1 12/24
630 leucine-rich repeat-containing G-protein coupled receptor 6 isoform 2 99294.1 62912472
1 (1 0 0
0 0)
6497, 2-2 R.LQELGFHNNNIK.A 1149.7 1 15/22
631 translocation protein SEC63 homolog 87996.4 6005872
1 (1 0 0
0 0)
5056, 2-2 R.VLLLSHLAR.M 611.7 2 12/16
632 transient receptor potential cation channel subfamily M member 2 171224.5 4507689
1 (1 0 0
0 0)
7547, 2-2 -.M*EPSALRK.A 879.1 1 12/14
633 protein transport protein Sec24B isoform a 137416.6
11238221
2
5 (0 5 0
0 0)
7822, 2-2 R.TYINPFVSFIDQR.R 889.0 1 17/24
8073, 2-2 R.TYINPFVSFIDQR.R 1003.9 1 17/24
8075, 1-2 R.TYINPFVSFIDQR.R 866.1 1 17/24
8309, 1-2 R.TYINPFVSFIDQR.R 1082.9 1 17/24
8440, 1 R.TYINPFVSFIDQR.R 1443.2 1 21/24
634 L-lactate dehydrogenase A-like 6B 41942.7 15082234
1 (0 1 0
0 0)
9394, 1 K.LIIVSNPVDILTYVAWK.L 538.6 1 17/32
635 chromosome-associated kinesin KIF4A 139880.1
11668612
2
2 (1 1 0
0 0)
6677, 2-2 R.WENIATILEAKCALK.Y 518.3 2 13/28
7005, 1 R.WENIATILEAKCALK.Y 631.5 1 14/28
636 myosin-X 237344.3
15435497
9
1 (0 1 0
0 0)
7467, 1-2 K.EEVSSARASIIDK.W 783.0 5 15/24
637 tubulin beta-6 chain 49856.8 14210536
1 (0 1 0
0 0)
7450, 2-2 K.M*ASTFIGNSTAIQELFK.R 637.7 2 16/32
638 E3 ubiquitin-protein ligase TRIM23 isoform alpha 64066.3 4502197
2 (0 2 0
0 0)
7053, 2-2 R.DALLLIFANK.Q 1437.9 1 15/18
7276, 1-2 R.DALLLIFANK.Q 1608.5 1 15/18
639 acyl-CoA dehydrogenase family member 9, mitochondrial precursor 68760.0 21361497
1 (0 1 0
0 0)
9512, 1 K.VWITNGGLANIFTVFAK.T 1022.7 2 19/32
640 myosin-VI 148712.8 92859701
2 (0 2 0
0 0)
8430, 1-2 K.FKTQLNLLLDK.L 1514.3 4 15/20
8501, 1 K.FKTQLNLLLDK.L 1581.9 3 15/20
641 zinc finger CCHC domain-containing protein 3 43547.1 29648305
1 (0 1 0
0 0)
7487, 1-2 R.EKMGWAQVVKNLAEK.K 831.7 3 16/28
642 carbonyl reductase [NADPH] 3 30850.1 4502601
1 (0 1 0
0 0)
Page 127
7776, 1 K.EYGGLNVLVNNAAVAFK.S 800.2 2 18/32
643 importin subunit alpha-3 57810.5 34485722
1 (0 1 0
0 0)
4546, 1-2 K.IEVLQQHENEDIYK.L 580.5 2 15/26
644 gamma-parvin 37485.0 11545879
1 (0 1 0
0 0)
4850, 2-2 -.MEPEFLYDLLQLPK.G 1129.7 1 17/26
645 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase
2 114974.2 71043500
1 (0 1 0
0 0)
5594, 1-2 R.DRWGGEDWELLDR.I 838.1 2 16/24
646 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor 59150.1 12548785
2 (0 2 0
0 0)
8430, 2-2 R.LDVNKIFYKDIK.Q 877.1 2 14/22
8709, 1-2 R.LDVNKIFYKDIK.Q 639.4 3 13/22
647 ras-related protein Rab-1B 22171.0 13569962
1 (0 1 0
0 0)
7854, 1-2 K.NATNVEQAFM*TMAAEIK.K 645.5 2 16/32
648 fibroblast growth factor 10 precursor 23435.8 4758360
1 (0 1 0
0 0)
6936, 1 K.LYGSKEFNNDCKLK.E 794.0 2 16/26
649 transmembrane emp24 domain-containing protein 4 precursor 25942.6 33457308
1 (0 1 0
0 0)
4637, 1-2 R.QLLDQVEQIQK.E 741.5 2 15/20
650 cadherin-4 isoform 2 96396.6
35664022
1
3 (1 1 0
1 0)
5822, 2-2 K.VENPIDLYIYVIDM*NDNR.P 575.4 2 16/34
5986, 1-2 K.VENPIDLYIYVIDM*NDNR.P 542.3 1 15/34
6051, 1 K.VENPIDLYIYVIDM*NDNR.P 619.2 1 16/34
651 ras-related protein Rab-33B 25717.4 13786129
1 (0 1 0
0 0)
5244, 1-2 K.IQLWDTAGQER.F 882.1 1 15/20
652 ephrin type-A receptor 2 precursor 108265.8 32967311
1 (0 1 0
0 0)
5336, 1-2 R.TASVSINQTEPPK.V 742.5 2 15/24
653 T-complex protein 1 subunit alpha isoform a 60343.2 57863257
1 (0 1 0
0 0)
6174, 1 R.YINENLIVNTDELGR.D 1005.4 1 18/28
654 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform
1 206443.7 4758416
1 (0 1 0
0 0)
6840, 2-2 R.ENYVWNVLLHR.G 736.1 1 14/20
655 exportin-7 123906.4
15444889
2
1 (0 1 0
0 0)
5622, 1-2 R.NYVLNYLATRPK.L 966.1 1 14/22
656 dynein heavy chain 14, axonemal isoform 1 518563.2
22355593
5
1 (0 1 0
0 0)
5504, 2-2 K.EPNLENEKNLLDK.H 545.7 2 14/24
657 ATP-dependent DNA helicase Q4 133076.5
28400530
9
1 (0 1 0
0 0)
6680, 1-2 R.LKANLKGTLQAGPALGR.R 582.1 2 16/32
658 leiomodin-2 61675.0
15037850
3
1 (0 1 0
0 0)
6976, 1-2 K.QPNSILKEIK.N 890.9 2 15/18
Page 128
659 cytochrome P450 2J2 57610.3 18491008
1 (0 1 0
0 0)
5669, 1-2 R.NFGLGKKSLEER.I 806.2 3 14/22
660 thiosulfate sulfurtransferase 33428.7 17402865
1 (0 1 0
0 0)
6094, 1 K.TYEQVLENLESKR.F 643.1 2 13/24
661 inositol 1,4,5-trisphosphate receptor type 1 isoform 1 308536.7
26995469
0
1 (0 1 0
0 0)
6543, 2-2 R.NVGHNIYILAHQLAR.H 577.9 2 13/28
662 structural maintenance of chromosomes protein 2 135655.0
11034742
0
1 (0 1 0
0 0)
5830, 1-2 K.EQNNDSQLKIK.E 1143.1 2 14/20
663 testis-expressed sequence 2 protein 125997.8 38679909
1 (0 1 0
0 0)
5613, 2-2 K.GSVEEIM*SQPKQK.E 513.1 3 14/24
664 cytochrome P450 4F22 61957.9
15813853
0
1 (0 1 0
0 0)
6808, 2-2 R.VVVALTLLR.F 520.2 3 13/16
665 desmoglein-3 preproprotein 107532.4
11996471
8
1 (0 1 0
0 0)
5615, 2-2 K.PCREGEDNSKR.N 591.0 4 13/20
666 poly [ADP-ribose] polymerase 14 202798.2
15481319
9
1 (0 1 0
0 0)
7658, 2-2 K.VTIRPAATLVNEGR.P 508.0 2 13/26
667 peroxisomal membrane protein PEX14 41236.3 4758896
1 (0 1 0
0 0)
6630, 1-2 K.ATTSTNWILESQNINELK.S 544.2 2 17/34
668 uncharacterized protein C12orf56 isoform 2 53561.4
15379121
8
1 (0 1 0
0 0)
7486, 1-2 K.FLFPFHHTKANNKK.V 539.5 5 12/26
669 A disintegrin and metalloproteinase with thrombospondin motifs 20 preproprotein 214718.3
12443055
7
1 (0 1 0
0 0)
5858, 2-2 K.RSSEALEPM*PFR.T 748.3 2 14/22
670 annexin A3 36375.0 4826643
1 (0 1 0
0 0)
5331, 2-2 K.M*LISILTERSNAQR.Q 685.2 2 14/26
671 outer dense fiber protein 2 isoform 1 103066.6
31075040
0
1 (0 1 0
0 0)
7481, 2-2 K.DEMNKEIEAAR.R 749.9 2 13/20
672 usherin isoform B 575559.4
21984226
6
1 (0 1 0
0 0)
5667, 1 K.DRTSPSAPSGMEPPK.L 529.3 5 15/28
673 6-phosphofructokinase type C isoform 2 85315.5
33419170
1
1 (0 1 0
0 0)
4809, 1-2 R.GKKFTTDDSICVLGISK.R 672.8 2 14/32
674 titin isoform N2-B 2992860.
0
29104522
3
1 (0 1 0
0 0)
4358, 2-2 K.DEKSLVEESQLPEGR.K 563.8 5 13/28
675 leukocyte immunoglobulin-like receptor subfamily B member 5 isoform 3
precursor 52968.7
12598759
3
1 (0 1 0
0 0)
7744, 1 K.PVTLWCQGPLETEEYR.L 593.4 2 15/30
676 zinc finger protein 644 isoform 2 11723.8 41152091
1 (0 1 0
0 0)
Page 129
7672, 1-2 -.M*LIRQNLALDCK.Q 650.5 2 13/22
677 myotilin isoform a 55394.8 5803106
1 (0 1 0
0 0)
6932, 1 R.VTLLIKDVNKK.D 960.9 2 15/20
678 isochorismatase domain-containing protein 1 32236.5
10347198
7
1 (0 1 0
0 0)
5915, 1-2 K.GLGSTVQEIDLTGVK.L 592.9 2 15/28
679 X-linked interleukin-1 receptor accessory protein-like 2 precursor 78669.4 11225607
1 (0 1 0
0 0)
5444, 1-2 K.LLSLIKWK.G 687.5 1 13/14
680 exportin-5 136310.3 22748937
1 (0 1 0
0 0)
6971, 1-2 K.M*AEPFTKALDM*LDAEK.S 1009.4 2 18/30
681 killer cell lectin-like receptor subfamily F member 1 26562.4 7705574
1 (0 1 0
0 0)
6215, 2-2 K.IFFIKGPAKENSCAAIK.E 672.3 2 15/32
682 nucleoprotein TPR 267289.5
11415514
2
1 (0 1 0
0 0)
7277, 1-2 R.ELQELQDSLNAER.E 781.4 2 14/24
683 uncharacterized protein KIAA2026 228084.7
14861283
8
1 (0 1 0
0 0)
6656, 2-2 K.DVLNENLQR.K 621.1 2 13/16
684 guanylate cyclase soluble subunit alpha-3 isoform A 77452.1 67763816
1 (0 1 0
0 0)
4228, 2-2 K.NIQESLPQRK.T 835.4 2 13/18
685 ATPase family AAA domain-containing protein 5 207568.0 26080431
1 (0 1 0
0 0)
5993, 2-2 K.NNEEIGM*LLENNK.G 760.9 4 14/24
686 charged multivesicular body protein 5 isoform 1 24570.6
18940915
0
1 (0 1 0
0 0)
5823, 1-2 K.NKDGVLVDEFGLPQIPAS.- 678.4 2 18/34
687 coiled-coil domain-containing protein 164 87133.6
21741637
4
1 (0 1 0
0 0)
6377, 2-2 R.QRIEKLENEVK.T 685.3 3 12/20
688 DNA repair protein RAD52 homolog 46168.4
10963779
8
1 (0 1 0
0 0)
4641, 1-2 K.EAVTDGLKRALR.S 844.2 2 17/22
689 BTB/POZ domain-containing protein 18 77931.0
22302943
6
1 (0 1 0
0 0)
6178, 1-2 R.QNADNLSGTLLLK.R 1194.2 1 16/24
690 protein furry homolog 338871.6
11760635
5
2 (0 1 1
0 0)
5728, 2-2 R.DMPLNIFVK.I 664.4 3 11/16
5879, 1-2 R.DMPLNIFVK.I 736.0 5 11/16
691 60S ribosomal protein L14 23431.7 78000181
1 (0 1 0
0 0)
7775, 1-2 K.M*RNRIIK.N 634.4 3 9/12
692 ectopic P granules protein 5 homolog 292477.1 93204865
1 (0 0 1
0 0)
7467, 1-2 R.VEM*NENALVELK.K 860.3 2 14/22
693 tubulin beta-3 chain isoform 1 50432.4 50592996
1 (0 0 1
0 0)
7450, 2-2 K.MSSTFIGNSTAIQELFK.R 573.7 3 15/32
Page 130
694 cytochrome P450 2F1 precursor 55501.0 19743565
1 (0 0 1
0 0)
6682, 2-2 K.EALVDQGEEFSGR.G 584.1 3 15/24
695 uncharacterized protein C14orf45 61986.5
16629520
4
1 (0 0 1
0 0)
4002, 1-2 K.QDQEKDNM*IEKLK.Q 1513.9 1 17/24
696 muscle-related coiled-coil protein 41898.9 66472922
1 (0 0 1
0 0)
7487, 1-2 R.EMENAIKSVQIDLLK.L 869.3 2 16/28
697 uncharacterized protein C1orf168 82069.5
16670691
7
1 (0 0 1
0 0)
7923, 2-2 R.AKFQNLDAPPLPGPIK.F 817.4 2 15/30
698 meprin A subunit alpha precursor 84418.5
15307026
2
1 (0 0 1
0 0)
6677, 2-2 K.MTGSPSDRLVVWVRR.D 511.9 3 13/28
699 ras-related protein Rab-6B 23461.5 96975097
1 (0 0 1
0 0)
5244, 1-2 R.LQLWDTAGQER.F 882.1 1 15/20
700 LIM domain-binding protein 1 isoform 3 42809.1 4504969
1 (0 0 1
0 0)
4850, 2-2 R.LCVILEPM*QELMSR.H 852.3 3 15/26
701 39S ribosomal protein L55, mitochondrial isoform a 15128.3 31563362
1 (0 0 1
0 0)
7065, 1 R.RMLAM*PIDLDTLSPEER.R 667.1 1 16/32
702 heterogeneous nuclear ribonucleoprotein L isoform a 64132.4 52632383
1 (0 0 1
0 0)
5594, 1-2 R.RSGAMVKMAAAGGGGGGGR.Y 602.6 3 17/36
703 geminin 23565.0 7705682
1 (0 0 1
0 0)
5081, 1-2 K.QEEIKENIKNSSVPR.R 546.7 5 13/28
704 ret finger protein-like 1 35490.7
14940813
0
1 (0 0 1
0 0)
5331, 2-2 R.SGCITQNRQDLAER.F 521.0 4 12/26
705 matrix metalloproteinase-19 isoform rasi-1 preproprotein 57356.6 4505213
1 (0 0 1
0 0)
5879, 1-2 K.TLKYLLLGR.W 855.4 2 11/16
706 ras-related protein Rab-8B 23584.0 7706563
1 (0 0 0
1 0)
5244, 1-2 K.LQIWDTAGQER.F 882.1 1 15/20
707 tubulin polyglutamylase TTLL5 143576.5 50658079
1 (0 0 0
1 0)
6862, 2-2 K.LGGSVLGLSMEEIKVLRR.V 642.8 2 17/34
708 disintegrin and metalloproteinase domain-containing protein 12 isoform 1
preproprotein 99541.7 73747885
1 (0 0 0
1 0)
4458, 1-2 R.LLFTNKKTTIEK.L 500.3 2 13/22
709 FERM, RhoGEF and pleckstrin domain-containing protein 2 119887.7 7662310
1 (0 0 0
1 0)
6672, 1 K.KLEAVYKEFELQK.V 553.4 2 13/24
710 orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 82199.5 55749589
1 (0 0 0
1 0)
6682, 2-2 R.NAEILLKLINLGK.L 1354.2 1 17/24
711 60S ribosomal protein L5 34362.4 14591909 1 (0 0 0
Page 131
0 1)
7438, 1-2 K.VGLTNYAAAYCTGLLLAR.R 526.7 3 15/34
712 gamma-interferon-inducible protein 16 isoform 1 82587.7
33086475
3
1 (0 0 0
0 1)
7487, 1-2 R.M*VKSLLSNDLKLNLK.M 776.7 4 15/28
713 U5 small nuclear ribonucleoprotein 200 kDa helicase 244504.7 40217847
1 (0 0 0
0 1)
5132, 1 K.PFGSEEQLLPVEK.L 594.3 2 14/24
Table S6. Identification of proteins associated with LDs of human livers.
Gene Name GI Uniprot
protein DEFINITION Reference
lipid droplet
PLIN1 22371820
3 O60240 perilipin-1 12
PLIN2 34577059 Q99541 perilipin-2 14,17,18,21,23~26
PLIN3 31737352
4 O60664 perilipin-3 6,7,9,11,13~15,17~26,29,30
PLIN4 12293719
5 Q96Q06 perilipin-4 7,11,14~16,21~23,29,30
lipid metabolism
APOB 30066960
5 P04114 apolipoprotein B-100 precursor 5,13,19,25
APOA1 4557321 P02647 apolipoprotein A-I preproprotein 15,16,18,19,24
SLC27A2 22749961
9 O14975
very long-chain acyl-CoA synthetase isoform
1
FASN 41872631 P49327 fatty acid synthase 8,13,15
LSS 22417755
6 G5E9Q9 lanosterol synthase isoform 2
ACSL3 42794752 O95573 long-chain-fatty-acid--CoA ligase 3 14,19,21
ACSL1 40807491 P33121 long-chain-fatty-acid--CoA ligase 1
SCCPDH(CGI-49) 55770836 Q8NBX0 probable saccharopine dehydrogenase 14,19,21,23,24
ADH4 71565152 P08319 alcohol dehydrogenase 4
ADH1B 34577061 P00325 alcohol dehydrogenase 1B 5
RDH10 25282469 Q8IZV5 retinol dehydrogenase 10 19
HSD17B6 19743808 O14756 17-beta-hydroxysteroid dehydrogenase type
6
HSD17B13 21003211
0 Q7Z5P4
17-beta-hydroxysteroid dehydrogenase 13
isoform A 26
HSD17B13 21003211
2 Q7Z5P4
17-beta-hydroxysteroid dehydrogenase 13
isoform B 26
HSD17B4 31348281
0 P51659
peroxisomal multifunctional enzyme type 2
isoform 1 18
HSD11B1 5031765 P28845 corticosteroid 11-beta-dehydrogenase
isozyme 1
ADH1C 4501933 P00326 alcohol dehydrogenase 1C 5
CYP4F11 19308317
8 Q9HBI6 cytochrome P450 4F11 precursor 13,18,19,25
HSD17B2 4504503 P37059 estradiol 17-beta-dehydrogenase 2
Page 132
HSD17B12 7705855 Q53GQ0 estradiol 17-beta-dehydrogenase 12
CYP4A11 15893724
2 Q02928 cytochrome P450 4A11 13,18,19,25
CYP2D6 40805836 P10635 cytochrome P450 2D6 isoform 1
CYP2C19 4503219 P33261 cytochrome P450 2C19 precursor
CYP2C9 13699818 P11712 cytochrome P450 2C9 precursor
CYP2A7 15147328 P20853 cytochrome P450 2A7 isoform 2 precursor
CYP2E1 10834998 P05181 cytochrome P450 2E1 precursor
CYP2C8 31189330
9 P10632 cytochrome P450 2C8 isoform b 13,18,19,25
NSDHL 8393516 Q15738 sterol-4-alpha-carboxylate 3-dehydrogenase,
decarboxylating 17,19,23,25,26
CYB5R3 19379482
6 P00387 NADH-cytochrome b5 reductase 3 isoform 2 17,19,23,25
ACACB 13414206
2 O00763 acetyl-CoA carboxylase 2 precursor 13
MGLL 6005786 Q99685 monoglyceride lipase isoform 1 19,26
ALDH3A2 73466520 P51648 fatty aldehyde dehydrogenase isoform 1
ACSL5 42794756 Q9ULC5 long-chain-fatty-acid--CoA ligase 5 isoform a
ACADVL 76496475 P49748-1 very long-chain specific acyl-CoA
dehydrogenase, mitochondrial isoform 2
HSD17B11 14297672
9 Q8NBQ5 estradiol 17-beta-dehydrogenase 11 19
membrane traffic
ANXA6 71773329 E5RFF0 annexin A6 isoform 1 15
SCP2 19923233 P22307 non-specific lipid-transfer protein isoform 1
proprotein 11
RAB10 25622201
9 P61026 ras-related protein Rab-10 17,19,21,24
AP2B1 4557469 P63010 AP-2 complex subunit beta isoform b
RAB14 19923483 P61106 ras-related protein Rab-14 14,21
USO1 4505541 O60763 general vesicular transport factor p115
ABCD3 4506341 P28288 ATP-binding cassette sub-family D member
3 isoform a 15
COPB1 7705369 P53618 coatomer subunit beta
LMAN1 5031873 P49257 protein ERGIC-53 precursor 18
SEC23A 38202214 Q15436 protein transport protein Sec23A
COPG2 10913434
9 Q9UBF2 coatomer subunit gamma-2
COPA 14853685
3 P53621 coatomer subunit alpha isoform 2 9
EHHADH 26187853
9
Q08426-
2 peroxisomal bifunctional enzyme isoform 2
CLTC 4758012 Q00610 clathrin heavy chain 1 5
cell signal
GNB2L1 5174447 P63244 guanine nucleotide-binding protein subunit
beta-2-like 1
RAP1B 35445935
0 P61224 ras-related protein Rap-1b isoform 2 25
STAT3 21618340 P40763 signal transducer and activator of
transcription 3 isoform 1 24
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IQGAP2 11608933
7 Q13576 ras GTPase-activating-like protein IQGAP2
GNB2 20357529 P62879 guanine nucleotide-binding protein
G(I)/G(S)/G(T) subunit beta-2 15,18
NAI2 4504041 P04899 guanine nucleotide-binding protein G(i)
subunit alpha-2 isoform 1 15,18
PDCD6IP 22027538 Q8WUM
4
programmed cell death 6-interacting protein
isoform 1
Chaperone
HSP90B1 4507677 P14625 endoplasmin 17
HSPA5 16507237 P11021 78 kDa glucose-regulated protein 17,19,23,26
HSPA1A 19424807
2 P08107 heat shock 70 kDa protein 1A/1B 19
CANX 10716563
P27824 calnexin precursor 19,23,26
HSP90AA1 15379259
0 P07900 heat shock protein HSP 90-alpha isoform 1 17
endoplasmic reticulum
CES1 68508965 P23141 Liver carboxylesterase 1 5
SURF4 19557691 O15260 surfeit locus protein 4
SEC24B 11238221
2 O95487 protein transport protein Sec24B isoform a
DDOST 20070197 P39656 dolichyl-diphosphooligosaccharide--protein
glycosyltransferase 48 kDa subunit precursor 19,23
SEC24A 11617478
0 O95486 protein transport protein Sec24A isoform 1
RTN4 24431935 Q9NQC3 reticulon-4 isoform A 19
RPN2 35493916 P04844
dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 isoform 1
precursor
FMO5 22131667
2 P49326
dimethylaniline monooxygenase [N-oxide-
forming] 5 isoform 1
RRBP1 11061122
0 Q9P2E9 ribosome-binding protein 1
CES1 68508957 P23141 liver carboxylesterase 1 isoform c precursor 5
P4HB 20070125 P07237 protein disulfide-isomerase 19
POR 12713903
3 P16435 NADPH--cytochrome P450 reductase 2,3,14,19,29~31
SLC27A5 13325057 Q9Y2P5 bile acyl-CoA synthetase
Mitochondria
SLC25A13 7657581 Q9UJS0 calcium-binding mitochondrial carrier
protein Aralar2 isoform 2
GLUD2 31377775 P49448 glutamate dehydrogenase 2, mitochondrial
CPS1 16979091
5 P31327
carbamoyl-phosphate synthase ,
mitochondrial isoform a precursor
CPS1 17029579
7 P31327
carbamoyl-phosphate synthase [ammonia],
mitochondrial isoform c
PHB2 22130758
4 Q99623 prohibitin-2 isoform 1
HMGCS2 5031751 P54868 hydroxymethylglutaryl-CoA synthase,
mitochondrial isoform 1 precursor
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PHB 4505773 P35232 prohibitin 32
HADHB 4504327 P55084 trifunctional enzyme subunit beta,
mitochondrial precursor
MAOA 4557735 P21397 amine oxidase [flavin-containing] A
SDHA 15641600
3 P31040
succinate dehydrogenase [ubiquinone]
flavoprotein subunit, mitochondrial
BDH1 44680133 Q02338 D-beta-hydroxybutyrate dehydrogenase,
mitochondrial precursor
MAOB 38202207 P27338 amine oxidase [flavin-containing] B
ATP5F1 32189394 P24539 ATP synthase subunit beta, mitochondrial
ATP5A1 4757810 P25705 ATP synthase subunit alpha, mitochondrial
HADHA 20127408 P40939 trifunctional enzyme subunit alpha,
mitochondrial 18
other proteins
HIST1H2AD 10800130 P20671 histone H2A type 1-D 10,13
PGM1 21361621 P36871 phosphoglucomutase-1 isoform 1
DHRS1 20986290
1 Q96LJ7
dehydrogenase/reductase SDR family
member 1 19
HBB 4504351 P68871 hemoglobin subunit delta
MGST1 9945306 P10620 microsomal glutathione S-transferase 1
METTL7A 89145417 Q9H8H3 methyltransferase-like protein 7A 19
VDAC1 4507879 P21796 voltage-dependent anion-selective channel
protein 1 15,18
EPHX1 20986283
7 P07099 epoxide hydrolase 1 19
SULT1A2 4507303 P50226 sulfotransferase 1A2
EPHX2 27597073 P34913 epoxide hydrolase 2
C4BPA 4502503 P04003 C4b-binding protein alpha chain precursor
POTEF 15379135
2 A5A3E0 POTE ankyrin domain family member F
UGT2A1 33360924
5 Q9Y4X1 UDP-glucuronosyltransferase 2A2
UGT2B28 33303381
1 Q9BY64
UDP-glucuronosyltransferase 2B28 isoform
2
UGT1A4 6005930 P22310 UDP-glucuronosyltransferase 1-4
UGT2B7 19019438
9 P16662 UDP-glucuronosyltransferase 2B7
UGT1A9 11276085 O60656 UDP-glucuronosyltransferase 1-9
UGT2B15 11651729
9 P54855 UDP-glucuronosyltransferase 2B15
SORD 15662757
1 Q00796 sorbitol dehydrogenase 5
TPP1 5729770 O14773 tripeptidyl-peptidase 1 preproprotein
PON1 19923106 P27169 serum paraoxonase/arylesterase 1 precursor
PHGDH 23308577 O43175 D-3-phosphoglycerate dehydrogenase 15
SULT2A1 29540545 Q06520 bile salt sulfotransferase
MTHFD1 22213663
9 P11586 C-1-tetrahydrofolate synthase, cytoplasmic
DIAPH1 11939575
8 O60610 protein diaphanous homolog 1 isoform 1
ALDH8A1 30150069
8 Q9H2A2
aldehyde dehydrogenase family 8 member
A1 isoform 3
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ALB 4502027 P02768 serum albumin preproprotein 17
FTCD 11140815 O95954 formimidoyltransferase-cyclodeaminase
UGP2 48255966 Q16851 UTP--glucose-1-phosphate
uridylyltransferase isoform a
DAK 20149621 Q3LXA3
bifunctional ATP-dependent
dihydroxyacetone kinase/FAD-AMP lyase
(cyclizing)
FMO3 50541961 P31513 dimethylaniline monooxygenase [N-oxide-
forming] 3
protein translation, modification degradation
EEF2 4503483 P13639 elongation factor 2
EEF1A2 4503475 Q05639 elongation factor 1-alpha 2 15
GCN1L1 54607053 Q92616 translational activator GCN1 13
SEC14L2 7110715 O76054 SEC14-like protein 2 isoform 1
CAND1 21361794 Q86VP6 cullin-associated NEDD8-dissociated protein
1
Cytoskeleton
SPTBN1 11238225
0 Q01082 spectrin beta chain, brain 1 isoform 1
PLEC1 41322908 Q15149-1 plectin isoform 1e
SPTAN1 19459550
9 Q13813 spectrin alpha chain, brain isoform 1
TLN1 22302941
0 Q9Y490 talin-1 15
MYH9 12667788 P35579 myosin-9
MYO1B 44889481 O43795 myosin-Ib isoform 2
JUP 12056468 P14923 junction plakoglobin
LMNA 27436946 P02545 prelamin-A/C isoform 1
VIM 62414289 P08670 vimentin 14,15,20,21,25
TUBA1A 17986283 Q71U36 tubulin alpha-1A chain
TUBA1B 57013276 P68363 tubulin alpha-1B chain 19
TUBB2A 4507729 Q13885 tubulin beta-2A chain 19
TUBB4B 5174735 P68371 tubulin beta-2C chain
ACTB 4501885 P60709 actin, cytoplasmic 1 19
CDH4 35664022
1 P55283 cadherin-4 isoform 2
CTNNA1 55770844 P35221 catenin alpha-1
DSP 58530840 P15924 desmoplakin isoform I 1,3,4,27,28
VIL1 19439423
7 P09327 villin-1
ACTN4 12025678 O43707 alpha-actinin-4 19
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Table S7. A list of LD proteins up-regulated and down-regulated in human fatty livers identified by means
of 2D-LD-MS/MS.
Table S7. A list for up-and down-regulated Lipid droplet proteins in fatty livers as compared with control livers.
Protein names MW Accession Peptide
(Hits)
Up-regulated lipid droplet proteins
Band 1
1 long-chain-fatty-acid--CoA ligase 1 77942.9 40807491 31
2 trifunctional enzyme subunit alpha 82999.1 20127408 5
3 stress-70 protein, mitochondrial 73680.1 24234688 4
4 protein disulfide-isomerase A4 72931.9 4758304 3
5 very long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2
68058.1 76496475 2
Band 2
1 acetolactate synthase-like protein 67867.3 21361361 9
2 carnitine O-palmitoyltransferase 2, mitochondrial precursor 73776.6 4503023 9
3 ATP-binding cassette sub-family D member 3 isoform a 75475.5 4506341 4
4 liver carboxylesterase 1 isoform c 62392.5 68508957 4
5 perilipin-1 55990.0 223718203 3
6 long-chain-fatty-acid--CoA ligase 5 isoform a 82262.5 42794756 3
7 bile acyl-CoA synthetase 75384.7 13325057 3
8 acyl-coenzyme A synthetase ACSM2A, mitochondrial 64223.9 58082049 3
9 eukaryotic translation initiation factor 3 subunit L isoform 1 66726.6 7705433 2
Band 3
1 ATP synthase subunit alpha, mitochondrial 59750.3 4757810 19
2 cytochrome P450 2E1 56848.6 10834998 13
3 glutamate dehydrogenase 2, mitochondrial 61433.6 31377775 7
4 UDP-glucuronosyltransferase 2B7 60720.3 190194389 6
5 aldehyde dehydrogenase, mitochondrial 56380.9 25777732 5
6 perilipin-2 48075.1 34577059 6
7 cytochrome P450 2C19 55944.8 4503219 6
8 glutamate dehydrogenase 1, mitochondrial 61397.5 4885281 5
9 UTP--glucose-1-phosphate uridylyltransferase isoform a 56939.9 48255966 5
10 cytochrome P450 1A2 58407.1 73915100 5
11 UDP-glucuronosyltransferase 2B15 61036.0 116517299 4
12 cytochrome P450 4A11 59347.5 158937242 3
13 dimethylaniline monooxygenase [N-oxide-forming] 3 60033.2 50541961 4
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14 cytochrome P450 2C18 55710.4 13699816 3
15 cytochrome P450 4A22 59245.5 62952506 4
16 cytochrome P450 2C9 55627.6 13699818 2
Band 4
1 epoxide hydrolase 1 52948.5 209862837 33
2 perilipin-3 isoform 1 47074.7 255958282 14
3 arylacetamide deacetylase 45733.4 68299767 8
4 eukaryotic initiation factor 4A-II 46402.0 83700235 4
5 sulfide:quinone oxidoreductase, mitochondrial 49960.4 10864011 4
6 annexin A7 isoform 1 50315.4 4502111 4
7 synaptic vesicle membrane protein VAT-1 homolog 41920.0 18379349 4
8 argininosuccinate synthase 46530.1 16950633 3
9 adipocyte plasma membrane-associated protein 46480.1 24308201 2
Band 5
1 alcohol dehydrogenase 4 40221.5 71565152 3
Band6
1 17-beta-hydroxysteroid dehydrogenase 13 isoform B 29604.7 210032112 50
2 estradiol 17-beta-dehydrogenase 11 32935.6 142976729 13
3 retinol dehydrogenase 16 35673.2 150247226 8
4 NADH-cytochrome b5 reductase 3 isoform 2 31628.5 193794826 6
5 annexin A4 36084.8 4502105 6
6 electron transfer flavoprotein subunit alpha, mitochondrial isoform a
35079.3 4503607 5
7 2,4-dienoyl-CoA reductase, mitochondrial 36067.5 4503301 4
8 17-beta-hydroxysteroid dehydrogenase 13 isoform A 33655.2 210032110 6
9 short-chain dehydrogenase/reductase 3 33548.2 31543615 3
10 monoglyceride lipase isoform 1 34292.3 6005786 3
11 40S ribosomal protein S3a 29944.7 4506723 3
Band 7
1 prohibitin 29803.9 4505773 6
2 17-beta-hydroxysteroid dehydrogenase type 6 35965.5 19743808 5
3 vesicle-associated membrane protein-associated protein B/C isoform 1
27228.2 4759302 2
Down-regulated lipid droplet proteins
Band 8
1 ferritin light chain 20019.5 20149498 8
2 ferritin heavy chain 21225.5 56682959 3
3 solute carrier family 2, facilitated glucose transporter member 2
57489.2 4557851 2
4 ubiquitin-60S ribosomal protein L40 precursor 14728.2 77539055 2
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5 palmitoyl-protein thioesterase 1 isoform 1 precursor 34193.3 4506031 2
Band 9
1 myosin-9 226529.8 12667788 13
2 talin-1 269764.4 223029410 3
3 putative ATP-dependent RNA helicase DHX33 isoform 1 78873.6 20336302 2
4 hemoglobin subunit beta 15998.3 4504349 2
Band10
1 heat shock protein HSP 90-alpha isoform 1 98160.4 153792590 3
2 heat shock protein HSP 90-beta 83263.6 20149594 5
3 mannosyl-oligosaccharide glucosidase isoform 1 91917.0 149999606 2
4 calnexin precursor 67567.8 10716563 2
Band 11
1 serum albumin preproprotein 69366.4 4502027 24
2 bile acyl-CoA synthetase precursor 75384.7 13325057 8
3 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor
68569.0 4506675 7
4 heat shock 70 kDa protein 1A/1B 70051.8 194248072 3
5 calcium-binding mitochondrial carrier protein Aralar2 isoform 2
74175.1 7657581 2
6 phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform 1 precursor
70729.6 66346721 2
7 annexin A6 isoform 1 75872.8 71773329 2
8 calcium-binding mitochondrial carrier protein Aralar1 74761.4 21361103 2
Band12
1 prostaglandin reductase 1 isoform 2 32894.9 226056130 7
2 elongation factor 1-alpha 2 50469.8 4503475 4
3 glyceraldehyde-3-phosphate dehydrogenase 36053.0 7669492 4
4 60S ribosomal protein L4 47697.0 16579885 3
5 actin-related protein 3 47370.9 5031573 3
6 elongation factor 1-alpha 1 50140.5 4503471 3
7 glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic 37567.4 33695088 3
8 thioredoxin domain-containing protein 5 isoform 1 precursor 47628.6 42794771 2
9 aldo-keto reductase family 1 member C4 37094.6 325652083 3
10 methyltransferase-like protein 7A precursor 28318.9 89145417 3
11 annexin A9 38363.3 145864465 2
12 transaldolase 37539.9 5803187 2
13 aldo-keto reductase family 1 member C1 36788.1 5453543 2
14 vimentin 53651.3 62414289 2
Page 139
Table S8. 4 KEGG pathways enriched in 58 LD proteins up-regulated in fatty liver.
Category Term Genes PValue
KEGG_PATHWAY hsa00830:Retinol metabolism
190194389,
158937242,
73915100,
4503219,
71565152,
150247226,
31543615,
13699818,
116517299,
62952506,
13699816
8.22E-13
KEGG_PATHWAY hsa00980:Metabolism of xenobiotics
by cytochrome P450
190194389,
10834998,
73915100,
209862837,
4503219,
71565152,
13699818,
116517299,
13699816
3.32E-09
KEGG_PATHWAY hsa00982:Drug metabolism
50541961,
190194389,
10834998,
73915100,
4503219,
71565152,
13699818,
116517299,
13699816
4.35E-09
KEGG_PATHWAY hsa00591:Linoleic acid metabolism
10834998,
73915100,
4503219,
13699818,
13699816
3.05E-05
Page 140
Figure S1. Histological and morphological examination of hepatic tissues and LDs in human subjects
with or without simple steatosis. A) Light micrograph of representative normal liver (left) and non-
alcoholic fatty liver (right) stained with HE. B) Oil red O staining demonstrating massive neutral lipid
accumulation in fatty liver (right panel). Little staining was observed in normal liver (left panel). C)
Masson staining of normal liver and non-alcoholic fatty liver. Note: no fibrotic lesion was observed in
either normal or steatotic liver. D) Electron micrographs of sections of livers stained with 2% (w/v) uranyl
acetate. The arrowheads indicate the LDs, asterisk indicates the nuclei, magnification 40,000×.
Page 141
Figure S2. Identification of the LD-associated protein expression profile of human livers without
NAFLD. A) LD proteins isolated from 3 normal human livers were processed for gel electrophoresis and
stained with silver staining. Samples from 3 livers were processed for mass spectrometry. B) Venn diagram
shows the cross-correlation of identified LD proteins from 3 samples. Numbers inside the circle or overlaps
separately represent proteins only belonging to or common to corresponding data sets. Note: 148 LD
proteins were found to be shared by all 3 samples. C) All human liver LD proteins identified by 2D-LC-
MS/MS were categorized by subcellular distributions and known functions based on literature or NCBI
online sources.
Page 142
Figure S3. Bioinformatics analysis of identified LD proteins in fatty livers and control livers. A)
Association network of identified LD proteins in fatty livers and control livers by a website program
STRING against human database. Network edges represent predicted functional associations with different
line colors standing for various types of evidence used for predicting: red, fusion evidence; green,
neighborhood evidence; blue, co-occurrence evidence; purple, experimental evidence; yellow, text-mining
evidence; black, co-expression evidence. B) The KEGG pathway showing retinol metabolism was
significantly increased in the livers of patients with NAFLD. Proteins found in our comparative proteomic
study were labeled in red.
Page 144
Figure S4. Tissue distribution and adenovirus-mediated hepatic overexpression of 17β-HSD13 in
C57BL/6 mice. A) Tissue distribution of 17β-HSD13 in male and female C57BL/6 mice.17β-HSD13
mRNA levels were determined by real-time PCR in various mouse tissues. 17β-HSD13 was predominantly
expressed in the liver and appeared to be higher in female mice than male mice. *p<0.05, n=3. B)
Validation of the recombinant 17β-HSD13 adenovirus in HepG2 cells. Western blot analysis shows a dose-
dependent expression of 17β-HSD13 protein. C) Adenovirus-mediated overexpression of 17β-HSD13 for 4
days markedly increased 17β-HSD13 protein levels in liver. D) Hepatic overexpression of 17β-HSD13 had
little effect on serum TG and CHO levels.
Page 146
Figure S5. Overexpression of 17β-HSD13 increased the size of LD in both HepG2 and Huh7 cell
lines. A) HepG2 cells transfected with a GFP expression vector (GFP) or a 17β-HSD13-GFP construct
were visualized by confocal microscopy. Green: 17β-HSD13-GFP or GFP; Mauve: Nile red; Blue:
Nuclear. B) Huh7 cells were transfected with GFP or 17β-HSD13-GFP for 24 h. The size of the purified
LDs was measured by a Delsa Nano C particle analyzer (Beckman). The size of LDs was distributed in the
range of 50 nm to 3,000 nm. C) The diameters of LDs were larger in 17β-HSD13-GFP transfected cells
than that of GFP. *p<0.05, **p<0.01 vs. control (GFP), n=5.