Six Steps to Grow Your Brain

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Six Steps to a Better BrainMajid Fotuhi, MD PhD

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New Discoveries

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This book may be the most important youll ever read. Certainly,what Dr. Fotuhi teaches in this book has changed my life.

Michael Roizen, M.D. Chairm an of th e Wellness Ins t i tut e- The Cleveland Clinic

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ObjectivesWhat happens to our brain withaging?

How to reverse age-related brainatrophy?

Brain Fitness Program

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Memory Lapses

Memory lapses or Alzheimers?

Age-Associated

MemoryImpairment MCI

Alzheimers

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Short-term: HippocampusLong-term: Cortex

Cortex Hippocampus

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Hippocampus

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Beautiful Neurons in Hippocampus

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With Aging,Hippocampus Atrophies Faster

than the Rest of the BrainHippocampus shrinks by about 0.5% peryear after age 50

That is the reason memory lapses becomemore frequent after age 50

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Overlapping Causes of Atrophy in Hippocampus

Obesity

Stroke

Sleep Apnea

Concussion AD

Diabetes

Hypertension

Stress

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Less Brain Volume in Patients withSleep Apnea

Am J Resp ir Crit Care Med 2002; 166:1382 7

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Vascular Risk Factors Shrink theBrain, Especially the Hippocampus

MultipleVascular

Risk Factors

NoVascular

Risk Factors

HippocampusHippocampus

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Obesity Shrinks the Brain

Associated with reducedbrain volume

Ward , et al., 2005

Slows cognitive functionDebett e, et al., 2011

Brains of overweight andobese individualsappeared 8 and 16 years

older, respectivelyRaji, et al., 2010

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Brain Research Volu me 1280, 14 Jul y 2009, Pages 186 194

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Stress ShrinksBrain Cells in Hippocampus

StressControl

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Alzheimers:Plaques and Tangles

Plaques: gum-likecollection of a proteincalled Amyloid

Tangles: abnormalaggregation of a proteincalled Tau

Inflammation

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Why do we forget names?

HypertensionDiabetes

Alcoholism

DepressionHeart failureObesity

High cholesterolHead trauma

Aging

Poor sleepToo much workInformation overload

Too many responsibilitiesFatiguePoor attention

Poor dietCant do it mentality

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ObjectivesWhat happens to our brain withaging?

How to reverse age-related brainatrophy?

Brain Fitness Program

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6 Steps to Grow Your Brain

1. Get Fit2. Tease Your Memory

3. Eat Well &Take DHA4. Sleep

5. Relax Your Mind

6. Start Early

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1. Hippocampus Grows Biggerwith Getting Fit

Eriks on , PNAS 2011

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Arch Gen Psyc hiatry, 2010

Hippocampus Grows Biggerwith Exercise, Even After 3 Months

After

Before

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Draganski et al . J Neuros ci 2006; 26:6314 7

2. Hippocampus Grows Bigger withMemorization Training

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3. Hippocampus Grows Bigger withEating Well & Taking DHA

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4. Hippocampus Grows Bigger withTreatment of Sleep Apnea

Canesa, Am erican Jou rnal of Respiratory Medicin e, 2011

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5. Hippocampus Grows Bigger withRelaxing Your Mind

Holzel , Psych iatric Research , 201127

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ObjectivesWhat happens to our brain withaging?

How to reverse age-related brainatrophy?

Brain Fitness Program

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ComprehensiveDiagnostics to

Evaluate Brain Health

Customized TreatmentProgram to Maximize

Brain Performance

NeurExpands Unique Integrative Approach

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Remarkable Results

Hippocampus

After

Before

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DiabetesHypertensionObesitySleep ApneaHead TraumaGeneticsStress

ExerciseCognitive StimulationMeditationSleepDiet - DHA

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