Top Banner
SDRA Retentissement hémodynamique Antoine Vieillard-Baron, Boulogne, France
37

SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Apr 16, 2018

Download

Documents

phamcong
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Page 1: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

SDRA

Retentissement hémodynamique

Antoine Vieillard-Baron, Boulogne, France

Page 2: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

98 ARDS

AJRCCM 2000

Page 3: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Table S3 % of patients with vasopressors 1 day after randomization HFO group: 78% Control group: 58%

Page 4: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

0

10

20

30

40

50

60

70

80

90

100

0 1 2 3 ≥4Number of extrapulmonary organ failures

Mor

talit

y, %

p<0.00001

N=2

N=14

N=26

N=27

N=40

95%CI 1.7-15.7

95%CI 12.9-28.3

95%CI 32.0-52.3

95%CI 45.5-68.7

95%CI 87.4-98.6

Page 5: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

•  Diminution du shunt pulmonaire: Sous-estimation de l’atteinte pulmonaire

•  Effet basse PvO2: Surestimation de l’atteinte pulmonaire

•  Foramen ovale perméable: Surestimation de

l’atteinte pulmonaire

INTERPRETATION ERRONEE DES GAZ DU SANG

Page 6: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Kumar NEJM 1970

PEEP 13

Page 7: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Crit Care Med 2010

Prevalence 19,2%

Page 8: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 9: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Intensive Care Med 2003

•  401 ARDS

–  53% had associated circulatory failure

–  26% in a context of severe sepsis or septic shock

Page 10: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

TOUT FAIRE POUR LIMITER L’INSUFFISANCE CIRCULATOIRE

VENTILATION PROTECTRICE POUR LE VD

Page 11: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Crit Care Med 2014

Page 12: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

RV LV

RV

LV VCI

A

B

C

D

IVC

Page 13: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Minerva Anestesiologica 2012

Page 14: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Le CPA a un impact sur l’hémodynamique

AJRCCM 2002

Prospective study, 226 ARDS ACP 22%

Page 15: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Le CPA a un impact sur le pronostic

Boissier ICM 2013

Page 16: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Crit Care Med 2012

Page 17: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 18: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

1980-2006 352 ARDS with ECHO

%

Page 19: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Boissier et al. ICM 2013

Page 20: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Day 1 420 x 25

Pplat 29 cmH2O NE 1.5 mg/heure

Day 3 350 x 28

Pplat 25 cmH2O NE 0.25 mg/heure

Intensive Care Med 2013

Page 21: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 22: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Prospective study, 200 ARDS ACP 22,5%

Page 23: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

D1, 7 p.m PaCO2: 88 mmHg

BD 12 mmol/l

D2, 7 a.m PaCO2: 55 mmHg

BD 2.3 mmol/l

Control hypercapnia (Avoid intrinsic PEEP)

Page 24: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 25: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Decrease in RVSI (%)

Page 26: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

PEEP 7 cmH2O PEEP 14 cmH2O

Page 27: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Decrease in RVSI (%)

Page 28: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Duggan M, AJRCCM 2003

Page 29: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

•  H, 41 y •  Obese, BMI 59.2 kg/m2 (P 169 kg) •  Sleeve/gastrectomy •  ARF related to aspiration •  Temperature 39°C, NE 1 mg/hour

Page 30: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 31: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

PEEP 7

PEEP 14

Page 32: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

PEEP 7 cmH2O PEEP 15 cmH2O

Page 33: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 34: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:
Page 35: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Chest 2007

Before PP After 18 hours PP

Page 36: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

Guerin et al.

Une parfaite protection du VD

PEEP < 10 cmH2O Pplat < 25 cmH2O PaCO2 ~ 50 mmHg

Page 37: SDRA Retentissement hémodynamique - JIVD - AER - … · Retentissement hémodynamique ... • 401 ARDS – 53% had associated circulatory failure ... 09h30-Vieillard-Baron.ppt Author:

CONCLUSION

Laissez le ventricule droit respirer!