SCHRIFTENVERZEICHNIS HELMUT … · Web viewlist Helmut Kettenmann Original Papers 1. Gilbert P., Kettenmann H., Orkand R.K. and Schachner M. (1982) Immunocytochemical cell identification

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LIST HELMUT KETTENMANN

Original Papers

1. Gilbert P., Kettenmann H., Orkand R.K. and Schachner M. (1982) Immunocytochemical cell identification in nervous system culture combined with intracellular injection of a blue fluorescing dye (SITS). Neurosci. Lett. 34: 123-128.

2. Kettenmann H., Orkand R.K., Lux H.D. and Schachner M. (1982) Single potassium channel currents in cultured mouse oligodendrocytes. Neurosci. Lett. 32: 41-46.

3. Sonnhof U., Förderer R., Schneider W. and Kettenmann H. (1982) Cell puncturing with a step motor driven manipulator with simultaneous measurement of displacement. Pflügers Arch. 392: 295-300.

4. Kettenmann H. and Orkand R.K. (1983) Intracellular SITS injection dye-uncouples mammalian oligodendrocytes in culture. Neurosci. Lett. 39: 21-26.

5. Kettenmann H., Orkand R.K. and Schachner M. (1983) Coupling among identified cells in mammalian nervous system cultures. J. Neurosci. 3: 506-516.

6. Kettenmann H., Sonnhof U. and Schachner M. (1983) Exclusive potassium dependence of the membrane potential in cultured mouse oligodendrocytes. J. Neurosci. 3: 500-505.

7. Kettenmann H., Wienrich M. and Schachner M. (1983) Antibody L1 ejected from a micropipette identifies neurons without altering electrical activity. Neurosci. Lett. 41: 85-90.

8. Gilbert P., Kettenmann H. and Schachner M. (1984) Gamma-aminobutyric acid directly depolarizes cultured oligodendrocytes. J. Neurosci. 4: 561-569.

9. Kettenmann H., Backus K.H. and Schachner M. (1984) Aspartate, glutamate and gamma-aminobutyric acid depolarize cultured astrocytes. Neurosci. Lett. 52: 25-29.

10. Kettenmann H., Gilbert P. and Schachner M. (1984) Depolarization of cultured oli-godendrocytes by glutamate and GABA. Neurosci. Lett. 47: 271-276.

11. Kettenmann H., Orkand R.K. and Lux H.D. (1984) Some properties of single potassium channels in cultured oligodendrocytes. Pflügers Arch. 400: 215-221.

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12. Kettenmann H., Sonnhof U., Camerer H., Kuhlmann S., Orkand R.K. and Schachner M. (1984) Electrical properties of oligodendrocytes in culture. Pflügers Arch. 401: 324-332.

13. Fischer G. and Kettenmann H. (1985) Cultured astrocytes form a syncytium after maturation. Exp. Cell Res. 159: 273-279.

14. Kettenmann H. (1985) A reversible decrease in electrical coupling of cultured mouse glial cells induced by superfusion from a micropipette. Neurosci. Lett. 59: 85-88.

15. Kettenmann H. and Schachner M. (1985) Pharmacological properties of Gamma-aminobutyric acid-, glutamate- and aspartate-induced depolarizations in cultured astrocytes. J. Neurosci. 5: 3295-3301.

16. Kettenmann H., Sommer I. and Schachner M. (1985) Monoclonal cell surface antibodies do not produce short-term effects on electrical properties of mouse oligodendrocytes in culture. Neurosci. Lett. 54: 195-199.

17. Kettenmann H. (1987) K+ and Cl- uptake by cultured oligodendrocytes. Can. J. Physiol. Pharmacol. 65: 1033-1037.

18. Kettenmann H., Backus K.H. and Schachner M. (1987) Y-Aminobutyric acid opens Cl-channels in cultured astrocytes. Brain Res. 404: 1-9.

19. Kettenmann H., Sykova E., Orkand R.K. and Schachner M. (1987) Glial potassium uptake following depletion by intracellular ionophoresis. Pflügers Arch. 410: 1-6.

20. Backus K.H., Kettenmann H. and Schachner M. (1988) Effect of benzodiazepines and pentobarbital on the GABA-induced depolarization in cultured astrocytes. Glia, 1: 132-140.

21. Bormann J. and Kettenmann H. (1988) Patch-clamp study of γ-aminobutyric acid receptor Cl-

channels in cultured astrocytes. Proc. Natl. Acad. Sci. USA. 85: 9336-9340.

22. Kettenmann H. and Ransom B.R. (1988) Electrical coupling between astrocytes and between oligodendrocytes studied in mammalian cell cultures. Glia, 1: 64-73.

23. Kettenmann H. and Schlue W.R. (1988) Intracellular pH regulation in cultured mouse oligodendrocytes. J. Physiol. (Lond), 406: 147-162.

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24. Pritchett D.B., Sontheimer H., Gorman C.M., Kettenmann H., Seeburg P.H. and Schofield P.R. (1988) Transient expression shows ligand gating and allosteric potentiation of GABAA receptor

subunits. Science, 242: 1306-1308.

25. Sontheimer H., Kettenmann H., Backus K.H. and Schachner M. (1988) Glutamate opens

Na+/K+ channels in cultured astrocytes. Glia 1: 328-336.

26. Sontheimer H. and Kettenmann H. (1988) Heterogeneity of potassium currents in cultured oligodendrocytes. Glia, 1: 415-420.

27. Backus. K.H., Kettenmann H. and Schachner M. (1989) Pharmacological characterization of the glutamate receptor in cultured astrocytes. J. Neurosci. Res. 22: 274-282.

28. Hoppe D. and Kettenmann H. (1989) GABA triggers a Cl- efflux from cultured mouse oli-godendrocytes. Neurosci. Lett. 97: 334-339.

29. Hoppe D. and Kettenmann H. (1989) Carrier-mediated Cl- transport in cultured mouse oligodendrocytes J. Neurosci. Res. 23: 467-475.

30. Hoppe D., Lux H.-D., Schachner M. and Kettenmann H. (1989) Activation of K+ currents in cultured Schwann cells is controlled by extracellular pH. Pflügers Arch. 415: 22-28.

31. MacVicar B.A., Tse F.W.Y., Crichton S.A. and Kettenmann H. (1989) GABA-activated Cl-

channels in astrocytes of hippocampal slices. J. Neurosci. 9: 3577-3583.

32. Pritchett D.B., Sontheimer H., Shivers B.D., Ymer S., Kettenmann H., Schofield P.R. and Seeburg P.H. (1989) Importance of a novel GABAA receptor subunit for benzodiazepine

pharmacology. Nature, 338: 582-585.

33. Schofield P.R., Pritchett D.B., Sontheimer H., Kettenmann H. and Seeburg P.H. (1989) Sequence and expression of human GABAA receptor 1 and 1 subunits. FEBS Lett. 244: 361-

364.

34. Sontheimer H., Becker C.-M., Pritchett D.B., Schofield P.R., Grenningloh G., Kettenmann H., Betz H. and Seeburg P.H. (1989) Functional chloride channels by mammalian cell expression of rat glycine receptor subunit. Neuron, 2: 1491-1497.

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35. Sontheimer H., Perouansky M., Hoppe D., Lux H.D., Grantyn R. and Kettenmann H. (1989)

Glial cells of the oligodendrocyte lineage express proton-activated Na+ channels. J. Neurosci. Res. 24: 496-500.

36. Sontheimer H., Trotter J., Schachner M. and Kettenmann H. (1989) Channel expression correlates with differentiation stage during the development of oligodendrocytes from their precursor cells in culture. Neuron, 2: 1135-1145.

37. Wienrich M. and Kettenmann H. (1989) Activation of substance P receptors leads to membrane potential responses in cultured astrocytes. Glia, 2: 155-160.

38. Ballanyi K. and Kettenmann H. (1990) Intracellular Na+ activity in cultured mouse oligodendrocytes. J. Neurosci. Res. 26: 455-460.

39. Blankenfeld G. v., Ymer S., Pritchett D.B., Sontheimer H., Ewert M., Seeburg P.H. and Kettenmann H. (1990) Differential benzodiazepine pharmacology of mammalian recombinant GABAA receptors. Neurosci. Lett. 115: 269-273.

40. Kettenmann H., Hoppe D., Gottmann K., Banati R. and Kreutzberg G. (1990) Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages. J. Neurosci. Res. 26: 278-287.

41. Kettenmann H., Ransom B.R. and Schlue W.R. (1990) Intracellular pH shifts capable of uncoupling cultured oligodendrocytes are seen only in low HCO3-solution. Glia, 3: 110-117.

42. Kimelberg H.K. and Kettenmann H. (1990) Swelling-induced changes in electrophysiological properties of cultured astrocytes and oligodendrocytes. I. Effects on membrane potentials, input impedance and cell-cell coupling. Brain Res. 529: 255-261.

43. Kimelberg H.K., Anderson E. and Kettenmann H. (1990) Swelling-induced changes in electrophysiological properties of cultured astrocytes and oligodendrocytes. II. Whole-cell currents. Brain Res. 529: 262-268.

44. Ransom B.R. and Kettenmann H. (1990) Electrical coupling, without dye coupling, between mammalian astrocytes and oligodendrocytes in cell culture. Glia, 3: 258-266.

45. Verkhratsky A.N., Trotter J. and Kettenmann H. (1990) Cultured glial precursor cells from mouse cortex express two types of calcium currents. Neurosci. Lett. 112: 194-198.

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46. Backus K.H., Berger T. and Kettenmann H. (1991) Activation of neurokinin receptors

modulates K+ and Cl- channel activity in cultured astrocytes from rat cortex. Brain Res. 541: 103-109.

47. Banati R.B., Hoppe D., Gottmann K., Kreutzberg G.W. and Kettenmann H. (1991) A subpopulation of bone marrow-derived macrophage-like cells shares a unique ion channel pattern with microglia. J. Neurosci. Res. 30: 593-600.

48. Berger T., Schnitzer J. and Kettenmann H. (1991) Developmental changes in the membrane

current pattern, K+ buffer capacity and morphology of glial cells in the corpus callosum slice. J. Neurosci. 11: 3008-3024.

49. Blankenfeld G. v., Trotter J. and Kettenmann H. (1991) Expression and developmental regulation of a GABAA receptor in cultured murine cells of the oligodendrocyte lineage. Eur. J.

Neurosci. 3: 310-316.

50. Chvátal A. and Kettenmann H. (1991) Effect of steroids on Gamma-aminobutyrate-induced currents in cultured rat astrocytes. Pflügers Arch. 419: 263-266.

51. Hoppe D., Bastmeyer M., Blankenfeld G. v., Kettenmann H. and Stürmer C.A.O. (1991) Two populations of glial cells from fish optic nerve/tract with distinct electrophysiological properties. Exp. Brain Res. 87: 383-388.

52. Hoppe D., Chvátal A., Kettenmann H., Orkand R.K. and Ransom B.R. (1991) Characteristics of activity-dependent potassium accumulation in mammalian peripheral nerve in vitro. Brain Res. 552: 106-112.

53. Kettenmann H., Blankenfeld G. v. and Trotter J. (1991) Physiological properties of oligodendrocytes during development. Ann.NY.Acad.Sci. 633: 64-77.

54. Kleingoor C., Ewert M., Blankenfeld G. v., Seeburg P.H. and Kettenmann H. (1991) Inverse but not full benzodiazepine agonists modulate recombinanat 622 GABAA receptors in

transfected human embryonic kidney cells. Neurosci. Lett. 130: 169-172.

55. Marrero H., Orkand P.M., Kettenmann H. and Orkand R.K. (1991) Single channel recording from glial cells on the untreated surface of the frog optic nerve. Eur. J. Neurosci. 3: 813-819.

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56. Sontheimer H., Kettenmann H., Schachner M. and Trotter J. (1991) The neural cell adhesion

molecule (N-CAM) modulates K+ channels in cultured glial precursor cells. Eur. J. Neurosci. 3: 230-236.

57. Verkhratsky A.N., Hoppe D. and Kettenmann H. (1991) Single K+ channel properties in cultured mouse Schwann cells: Conductance and kinetics. J. Neurosci. Res. 28: 200-209.

58. Verkhratsky A.N., Hoppe D. and Kettenmann H. (1991) K+ channel properties in cultured

mouse Schwann cells: dependence on extracellular K+. J. Neurosci. Res. 28: 210-216.

59. Berger T., Schnitzer J., Orkand P.M. and Kettenmann H. (1992) Sodium and calcium currents in glial cells of the mouse corpus callosum slice. Eur. J. Neurosci. 4: 1271-1284.

60. Berger T., Walz W., Schnitzer J. and Kettenmann H. (1992) GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice. J. Neurosci. Res. 31: 21-27.

61. Blankenfeld G. v., Verkhratsky A.N. and Kettenmann H. (1992) Ca2+ channel expression in the oligodendrocyte lineage. Eur. J. Neurosci. 4: 1035-1048.

62. Bocchini V., Mazzolla R., Barluzzi R., Blasi E., Sick P. and Kettenmann H. (1992) An immortalized cell line expresses properties of activated microglial cells. J. Neurosci. Res. 31: 616-621.

63. Gimpl G., Walz W., Ohlemeyer C. and Kettenmann H. (1992) Bradykinin receptors in cultured astrocytes from neonatal rat brain are linked to physiological responses. Neurosci. Lett. 144: 139-142.

64. Kirchhoff F. and Kettenmann H. (1992) GABA triggers a [Ca2+]i increase in murine precursor

cells of the oligodendrocyte lineage. Eur. J. Neurosci. 4: 1049-1058.

65. Kirchhoff F., Ohlemeyer C. and Kettenmann H. (1992) A fast perfusion system for single cell physiology optimized for microscopes with water immersion objectives. Pflügers Arch. 420: 573-577.

66. Müller T., Möller T., Berger T., Schnitzer J. and Kettenmann H. (1992) Calcium entry through kainate receptors and resulting potassium-channel blockade in Bergmann glial cells. Science, 256: 1563-1566.

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67. Steinhäuser C., Berger T., Frotscher M. and Kettenmann H. (1992) Heterogeneity in the membrane current pattern of identified glial cells in the hippocampal slice. Eur. J. Neurosci. 4: 472-484.

68. Blankenfeld G. v., Ransom B.R. and Kettenmann H. (1993) Development of cell-cell coupling among cells of the oligodendrocyte lineage. Glia, 7: 322-328.

69. Brockhaus J., Ilschner S., Banati R.B. and Kettenmann H. (1993) Membrane properties of ameboid microglial cells in the corpus callosum slice from early postnatal mice. J. Neurosci. 13: 4412-4421.

70. Gimpl G., Kirchhoff F., Lang R.E. and Kettenmann H. (1993) Identification of neuropeptide Y receptors in cultured astrocytes from neonatal rat brain. J. Neurosci. Res. 34: 198-205.

71. Kleingoor C., Wieland H.A., Korpi E.R., Seeburg P.H. and Kettenmann H. (1993) Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue. NeuroReport, 4: 187-190.

72. Korpi E.R., Kleingoor C., Kettenmann H. and Seeburg P.H. (1993) Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor. Nature, 361: 356-359.

73. Müller T., Grosche J., Ohlemeyer C. and Kettenmann H. (1993) NMDA-activated currents in Bergmann glial cells. NeuroReport, 4: 671-674.

74. Reichelt W., Müller T., Pastor A., Pannicke T., Orkand P.M., Kettenmann H. and Schnitzer J. (1993) Patch-clamp recordings from Müller (glial) cell endfeet in the intact isolated retina and acutely isolated Müller cells of mouse and guinea-pig. Neuroscience, 57: 599-613.

75. Walz W., Ilschner S., Ohlemeyer C., Banati R. and Kettenmann H. (1993) Extracellular ATP

activates a cation conductance and a K+ conductance in cultured microglial cells from mouse brain. J. Neurosci. 13: 4403-4411.

76. Borges K., Ohlemeyer C., Trotter J. and Kettenmann H. (1994) AMPA/kainate receptor activation in murine oligodendrocyte precursor cells leads to activation of a cation conductance, calcium influx and blockade of delayed rectifying K+channels. Neuroscience, 63: 135-149.

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77. Jabs R., Kirchhoff F., Kettenmann H. and Steinhäuser C. (1994) Kainate activates Ca2+-

permeable glutamate receptors and blocks voltage-gated K+ currents in glial cells of mouse hippocampal slices. Pflügers Arch. 426: 310-319.

78. Jung M., Crang A.J., Blakemore W.F., Hoppe D., Kettenmann H. and Trotter J. (1994) In vitro and in vivo characterisation of glial cells immortalised with a temperature sensitive SV40 T antigen- containing retrovirus. J. Neurosci. Res. 37: 182-196.

79. Müller T., Fritschy J.M., Grosche J., Pratt G.D., Möhler H. and Kettenmann H. (1994)

Developmental regulation of voltage-gated K+ channel and GABAA receptor expression in

Bergmann glial cells. J. Neurosci. 14: 2503-2514.

80. Rigo J.-M., Belachew S., Lefebvre P.P., Leprince P., Malgrange B., Rogister B., Kettenmann H. and Moonen G. (1994) Astroglia-released factor shows similar effects as benzodiazepine inverse agonists. J. Neurosci. Res. 39: 364-376.

81. Steinhäuser C., Jabs R. and Kettenmann H. (1994) Properties of GABA and glutamate responses in identified glial cells of the mouse hippocampal slice. Hippocampus, 4: 19 -36.

82. Walz W., Gimpl G., Ohlemeyer C. and Kettenmann H. (1994) Extracellular ATP-induced currents in astrocytes: involvement of a cation channel. J. Neurosci. Res. 38: 12-18.

83. Blankenfeld G. v., Turner J., Ahnert-Hilger G., John M., Enkvist M.O.K., Stephenson F., Kettenmann H. and Wiedenmann B. (1995) Expression of functional GABAA receptors in

neuroendocrine gastropancreatic cells. Pflügers Arch. 430: 381-388.

84. Borges K. and Kettenmann H. (1995) Blockade of K+ channels induced by AMPA/kainate

receptor activation in mouse oligodendrocyte precursor cells is mediated by Na+ entry. J. Neurosci.

Res. 42: 579-593.

85. Borges K., Wolswijk G., Ohlemeyer C. and Kettenmann H. (1995) Adult rat optic nerve oligodendrocyte progenitor cells express a distinct repertoire of voltage- and ligand-gated ion channels. J. Neurosci. Res. 40: 591-605.

86. Chvátal A., Pastor A., Mauch M., Syková E. and Kettenmann H. (1995) Distinct populations of identified glial cells in the developing rat spinal cord slice: Ion channel properties and cell morphology. Eur. J. Neurosci. 7: 129-142.

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87. Fraser D.D., Duffy S., Angelides K.J., Perez-Velazquez J.L., Kettenmann H. and MacVicar B.A. (1995) GABAA/Benzodiazepine receptors in acutely isolated hippocampal astrocytes. J. Neurosci. 15: 2720-2732.

88. Ilschner S., Ohlemeyer C., Gimpl G. and Kettenmann H. (1995) Modulation of potassium currents in cultured murine microglial cells by receptor activation and intracellular pathways. Neuroscience, 66: 983-1000.

89. Jung M., Krämer E., Grzenkowski M., Tang K., Blakemore W., Aguzzi A., Khazaie K., Chlichlia K., Blankenfeld G. v., Kettenmann H. and Trotter J. (1995) Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo. Eur. J. Neurosci. 7: 1245-1265.

90. Kirischuk S., Möller T., Voitenko N., Kettenmann H. and Verkhratsky A. (1995) ATP-induced cytoplasmic calcium mobilization in Bergmann glial cells. J. Neurosci. 15: 7861-7871.

91. Kirischuk S., Neuhaus J., Verkhratsky A. and Kettenmann H. (1995) Preferential localization of active mitochondria in process tips of immature retinal oligodendrocytes. Neuroreport, 6: 737-741.

92. Kirischuk S., Scherer J., Kettenmann H. and Verkhratsky A. (1995) Activation of P 2-purinoreceptors triggered Ca2+ release from InsP3-sensitive internal stores in mammalian oligodendrocytes. J. Physiol. 483.1: 41-57

93. Kirischuk S., Scherer J., Möller T., Verkhratsky A. and Kettenmann H. (1995) Subcellular heterogeneity of voltage-gated Ca2+ channels in cells of the oligodendrocyte lineage. Glia, 13: 1-12.

94. Pastor A., Chvátal A., Syková E. and Kettenmann H. (1995) Glycine- and GABA-activated currents in identified glial cells of the developing rat spinal cord slice. Eur. J. Neurosci. 7: 1188-1198.

95. Bernstein M., Lyons S.A., Möller T. and Kettenmann H. (1996) Receptor-mediated calcium signalling in glial cells from mouse corpus callosum slices. J. Neurosci. Res. 46: 152-163. 96. Brockhaus J., Möller T. and Kettenmann H. (1996) Phagocytozing ameboid microglial cells studied in a mouse corpus callosum slice preparation. Glia, 16: 81-90.

97. Faff L., Ohlemeyer C. and Kettenmann H. (1996) Intracellular pH regulation in cultured microglial cells from mouse brain. J. Neurosci. Res. 46: 294-304.

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98. Haas S., Brockhaus J., Verkhratsky A. and Kettenmann H. (1996) ATP-induced membrane currents in ameboid microglia acutely isolated from mouse brain slices. Neuroscience, 75: 257-261.

99. Hanisch U.-K., Neuhaus J., Quirion R. and Kettenmann H. (1996) Neurotoxicity induced by interleukin-2: Involvement of infiltrating immune cells. Synapse, 24: 104-114.

100. Ilschner S., Nolte C. and Kettenmann H. (1996) Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia. Neuroscience, 73: 1109-1120.

101. Kirchhoff F., Mülhardt C., Pastor A., Becker C.-M. and Kettenmann H. (1996) Expression of glycine receptor subunits in glial cells of the rat spinal cord. J. Neurochem. 66: 1383-90.

102. Kirischuk S., Tuschick S., Verkhratsky A. and Kettenmann H. (1996) Calcium signalling in mouse Bergmann glial cells mediated by 1-adrenoreceptors and H1 histamine receptors. Eur. J. Neurosci. 8: 1198-1208.

103. Müller T., Möller T., Neuhaus J. and Kettenmann H. (1996) Electrical coupling among Bergmann glial cells and its modulation by glutamate receptor activation. Glia, 17: 274-284.

104. Nolte C., Möller T., Walter T. and Kettenmann H. (1996) Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton. Neuroscience, 73: 1091-1107.

105. Oland L.A., Müller T., Kettenmann H. and Hayashi J. (1996) Preparation of primary cultures and acute slices of the nervous system of the moth Manduca sexta. J. Neurosc. Methods, 69: 103-112.

106. Patt S., Labrakakis C., Bernstein M., Weydt P., Cervós-Navarro J., Nisch G. and Kettenmann H. (1996) Neuron-like physiological properties of cells from human oligodendroglial tumors. Neuroscience, 71: 601-611.

107. Patt S., Schmidt H., Labrakakis C., Weydt P., Fritsch M., Cervós-Navarro J. and Kettenmann H. (1996) Human central neurocytoma cells show neuronal physiological properties in vitro. Acta Neuropath. 91: 209-214.

108. Rufer M., Wirth S.B., Hofer A., Dermietzel R., Pastor A., Kettenmann H. and Unsicker K. (1996) Regulation of connexin-43, GFAP, and FGF-2 is not accompanied by changes in astroglial coupling in MPTP-lesioned, FGF-2-treated Parkinsonian mice. J. Neurosci. Res. 46: 606-617.

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109. Chvátal A., Berger T., Vorisek I., Orkand R.K., Kettenmann H. and Syková E. (1997) Changes in glial K+ currents with decreased extracellular volume in developing rat white matter. J. Neurosci. Res. 49: 98-106.

110. Hanisch U.-K., Lyons S.A., Prinz M., Nolte C., Weber J.R., Kettenmann H. and Kirchhoff F. (1997) Mouse brain microglia express interleukin-15 and its multimeric receptor complex functionally coupled to janus kinase activity. J. Biol. Chem. 272: 28853-28860.

111. Hanisch U.-K, Neuhaus J., Rowe W., Rossum D. van, Möller T., Kettenmann H. and Quirion R. (1997) Neurotoxic consequences of central long-term administration of interleukin-2 in rats. Neuroscience, 79: 799-818.

112. Kirischuk S., Kettenmann H. and Verkhratsky A. (1997) Na+/Ca2+ exchanger modulates kainate-triggered Ca2+ signaling in Bergmann glial cells in situ. FASEB J. 568: 566-572.

113. Kirchhoff F., Ohlemeyer C. and Kettenmann H. (1997) Expression of myelin-associated glycoprotein transcripts in murine oligodendrocytes. Neuroscience, 78: 561-570

114. Labrakakis C., Müller T., Schmidt K. and Kettenmann H. (1997) GABAA receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells. Neuroscience, 79: 177-189.

115. Labrakakis C., Patt S., Weydt P., Cervós-Navarro J., Meyer R. and Kettenmann H. (1997) Action potential-generating cells in human glioblastomas. J. Neuropathol. Exp. Neurol. 56: 243-254.

116. Möller T., Kann O., Prinz M., Kirchhoff F., Verkhratsky A. and Kettenmann H. (1997) Endothelin-induced calcium signaling in cultured mouse microglial cells is mediated through ETB

receptors. Neuroreport, 8: 2127-2131.

117. Möller T., Nolte C., Burger R., Verkhratsky A. and Kettenmann H. (1997) Mechanisms of C5a and C3a complement fragment-induced [Ca2+]i signaling in mouse microglia. J. Neurosci. 17: 615-624.

118. Nolte C., Kirchhoff F. and Kettenmann H. (1997) Epidermal growth factor is a motility factor for microglial cells in vitro: evidence for EGF receptor expression. Eur. J. Neurosci. 9: 1690-1698.

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119. Schmidt C., Ohlemeyer C., Labrakakis C., Walter T., Kettenmann H. and Schnitzer J. (1997) Analysis of motile oligodendrocyte precursor cells in vitro and in brain slices. Glia, 20: 284-298.

120. Tuschick S., Kirischuk S., Kirchhoff F., Liefeldt L., Paul M., Verkhratsky A. and Kettenmann H. (1997) Bergmann glial cells in situ express endothelinB receptors linked to cytoplasmic calcium signals. Cell Calcium, 21: 409-419.

121. Weydt P., Möller T., Labrakakis C., Patt S. and Kettenmann H. (1997) Neuroligand-triggered calcium signalling in cultured human glioma cells. Neurosci. Lett. 228: 91-94.

122. Zahn J. v., Möller T., Kettenmann H. and Nolte C. (1997) Microglial phagocytosis is modulated by pro- and anti-inflammatory cytokines. NeuroReport, 8: 3851-3856.

123. Labrakakis C., Patt S., Hartmann J. and Kettenmann H. (1998) Functional GABAA receptors on human glioma cells. Eur. J. Neurosci. 10: 231-238.

124. Labrakakis C., Patt S., Hartmann J. and Kettenmann H. (1998) Glutamate receptor activation can trigger electrical activity in human glioma cells. Eur. J. Neurosci. 10: 2153-2162.

125. Lyons S.A. and Kettenmann H. (1998) Oligodendrocytes and microglia are selectively vulnerable to combined hypoxia and hypoglycemia injury in vitro. J. Cerbr. Blood Flow Metabolism, 18: 521-530.

126. Pastor A., Kremer M., Möller T., Kettenmann H. and Dermietzel R. (1998) Dye coupling between spinal cord oligodendrocytes: Differences in coupling efficiency between gray and white matter. Glia, 24: 108-120.

127. Prinz M., Hanisch U.-K., Kettenmann H. and Kirchhoff F. (1998): Alternative splicing of mouse IL-15 is due to the use of an internal splice site in exon 5. Mol. Brain Res. 63: 155-162.

128. Schmidt-Ott K.M., Tuschick S., Kirchhoff F., Verkhratsky A., Liefeldt L., Kettenmann H. and Paul M. (1998): Single-cell characterization of endothelin system gene expression in the cerebellum in situ. J. Cardiovasc. Pharmacol. 31(S1): S364-S366.

129. Toescu E., Möller T., Kettenmann H. and Verkhratsky A. (1998) Long-term activation of capacitative Ca2+ entry in mouse microglial cells. Neuroscience, 86: 925-935.

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130. Draheim H.J., Prinz M., Weber J.R., Weiser T., Kettenmann H. and Hanisch U.-K. (1999) Induction of potassium channels in mouse brain microglia: cells acquire responsiveness to pneumococcal cell wall components during late development. Neuroscience, 89: 1379-1390.

131. Grosche J., Matyash V., Möller T., Verkhratsky A., Reichenbach A. and Kettenmann H. (1999) Microdomains for neuron-glia interaction: parallel fiber signaling to Bergmann glial cells. Nature Neurosci. 2: 139-43.

132. Kirischuk S., Kirchhoff F., Matyash V., Kettenmann H. and Verkhratsky A. (1999) Glutamate-triggered calcium signalling in mouse Bergmann glial cells in situ: role of inositol-1,4,5-trisphosphate-mediated intracellular calcium release. Neuroscience, 92: 1051-1059.

133. Prinz M., Kann O., Draheim H.J., Schumann R.R., Kettenmann H., Weber J.R. and Hanisch U.-K. (1999) Microglial activation by components of Gram-positive and –negative bacteria: Distinct and common routes to the induction of ion channels and cytokines. J. Neuropath. and Experimental Neurology, 58: 1078-1089.

134. Schmidt K., Eulitz D., Veh R.W., Kettenmann H. and Kirchhoff F. (1999) Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors. Brain Res. 843: 145-160.

135. Boucsein C., Kettenmann H. and Nolte C. (2000) Electrophysiological properties of microglial cells in normal and pathologic rat brain slices. Eur. J. Neurosci., 12: 2049-2058.

136. Lyons S.A., Pastor A., Ohlemeyer C., Kann O., Wiegand F., Prass K., Knapp F., Kettenmann H. and Dirnagl U. (2000) Distinct physiologic properties of microglia and blood-borne cells in rat brain slices after permanent middle cerebral artery occlusion. J. Cer. Blood Flow Met., 20: 1537-1549.

137. Minelli A., Lyons S., Nolte C., Verkhratsky A. and Kettenmann H. (2000) Ammonium triggers calcium elevation in cultured mouse microglial cells by initiating Ca2+ release from thapsigargin-sensitive intracellular stores. Pflügers Archiv, 439: 370-377.

138. Möller T., Kann O., Verkhratsky A. and Kettenmann H. (2000) Activation of mouse microglial cells affects P2 receptor signaling. Brain Res. 853: 49–59.139. Reuss B., Leung D.S.Y., Ohlemeyer C., Kettenmann H. and Unsicker K. (2000) Regionally distinct regulation of astroglial neurotransmitter receptors by fibroblast growth factor-2. Mol. Cell. Neurosci, 16: 42-58.

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140. Schmidt C., Ohlemeyer C., Kettenmann H., Reutter W. and Horstkorte R. (2000) Incorporation of N-propanoylneuraminic acid leads to calcium oscillations in oligodendrocytes upon the application of GABA. FEBS-Lett. 478: 276-280

141. Stohwasser R., Giesebrecht J., Kraft R., Müller E.-C., Häusler K.G., Kettenmann H., Hanisch U.-K. and Kloetzel P.-M. (2000) Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon- and lipopolysaccharide. Glia 29: 355-365.

142. Witting A., Müller P., Herrmann A., Kettenmann H. and Nolte C. (2000) Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J. Neurochem. 75: 1060-1070.

143. Diers-Fenger M., Kirchhoff F., Kettenmann H., Levine J.M. and Trotter J. (2001) AN2/NG2 protein-expressing glial progenitor cells in the murine CNS: isolation, differentiation, and association with radial glia. Glia 34: 213-228.

144. Fleige G., Nolte C., Synowitz M., Seeberger F., Kettenmann H. and Zimmer C. (2001) Magnetic labeling of activated microglia in experimental gliomas. Neoplasia 3(6): 489-499.

145. Hanisch U.-K., Prinz M., Angstwurm K., Häusler K.G., Kann O., Kettenmann H. and Weber J.R. (2001) The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls. Eur. J. Immunol. 31: 2104-2115.

146. Matyash V., Filippov V., Mohrhagen K. and Kettenmann H. (2001) Nitric oxide signals parallel fiber activity to Bergmann glial cells in the mouse cerebellar slice. Mol Cell Neurosci. 18: 664-670.

147. Mertsch K., Hanisch U.-K., Kettenmann H. and Schnitzer J. (2001) Characterization of microglial cells and their response to stimulation in an organotypic retinal culture system. J. Comp. Neurol. 431: 217-227.

148. Muth H., Elmshauser C., Broad S., Schipke C., Kettenmann H., Beck E., Kann M., Motta I. and Chen U. (2001) Cell-based delivery of cytokines allows for the differentiation of a doxycycline inducible oligodendrocyte precursor cell line in vitro. The Journal of Gene Medicine 3: 585-598.149. Nolte C., Matyash M., Pivneva T., Schipke C., Ohlemeyer C., Hanisch U.-K., Kirchhoff F. and Kettenmann H. (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia, 33: 72-86.

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150. Prinz M., Häusler K.G., Kettenmann H. and Hanisch U.-K. (2001) -adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia. Brain Res. 899: 264-270.

151. Schipke C., Ohlemeyer C., Matyash M., Nolte C., Kettenmann H. and Kirchhoff F. (2001) Astrocytes of the mouse neocortex express functional N-methyl-D-aspartate receptors. FASEB J 15: 1270-1272.

152. Schmidt-Ott K.M., Xu A.D., Tuschick S., Liefeldt L., Kresse W., Verkhratsky A., Kettenmann H. and Paul M. (2001) Hypoxia reverses dibutyryl-cAMP-induced stellation of cultured astrocytes via activation of the endothelin system. FASEB J. 15: 1227-1229.

153. Synowitz M., Ahmann P., Matyash M., Kuhn S.A., Hofmann B., Zimmer C., Kirchhoff F., Kiwit J.C.W. and Kettenmann H. (2001) GABAA-receptor expression in glioma cells is triggered by contact with neuronal cells. Eur J Neurosci. 14(8): 1294-1302.

154. Elmshäuser C., Bechtel J., Motta I., Schipke C., Kettenmann H., Schmalbruch H., Kann M., Beck E. and Chen U. (2002) Characterization of a mouse tet-on glia precursor cell line in vitro and in vivo using the electrophysiological measurement. J-Physiol. Paris. 96: 329-338.

155. Grosche J., Kettenmann H. and Reichenbach A. (2002) Bergmann glial cells form distinct morphological structures to interact with cerebellar neurons. Journal of Neuroscience Research. 68: 138-149.

156. Häusler K.G., Prinz M., Nolte C., Weber J.R., Schumann R.R., Kettenmann H. and Hanisch U.-K. (2002) Interferon- differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. Eur. J. Neurosci. 16: 2113-2122.

157. Matyash M., Matyash V., Nolte C., Sorrentino V. and Kettenmann H. (2002) Requirement of functional ryanodine receptor type 3 for astrocyte migration. FASEB J. Jan;16: 84-86.

158. Rappert A., Biber K., Nolte C., Lipp M., Schubel A., Lu B., Gerard N.P, Gerard C., Boddeke H.W.G.M. and Kettenmann H. (2002) Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. J. Immunol. 168: 3221-3226.159. Schipke C., Boucsein C., Ohlemeyer C., Kirchhoff F. and Kettenmann H. (2002) Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices. FASEB J. 16: 255-257.

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160. Boucsein C., Zacharias R., Färber K., Pavlovic S., Hanisch U.-K. and Kettenmann H. (2003) Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro. Eur. J. Neurosci., 17: 2267-2276.

161. Filippov V., Kronenberg G., Pivneva T., Reuter K., Steiner B., Wang L.-P., Yamaguchi M., Kettenmann H. and Kempermann G. (2003) Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol. Cell Neurosci., 23: 373-382.

162. Geißler D., Kresse W., Wiesner B., Bendig J., Kettenmann H. and Hagen V. (2003) DMACM-caged adenosine nucleotides: Ultrafast phototriggers for ATP, ADP, and AMP activated by long-wavelength irradiation. ChemBioChem, 4: 162-170.

163. Hoffmann A., Kann O., Ohlemeyer C., Hanisch U-K. and Kettenmann H. (2003) Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function. J. Neurosci. 23: 4410-4419.

164. Israel J.M., Schipke C., Ohlemeyer C., Theodosis D.T. and Kettenmann H. (2003) GABAA

receptor-expressing astrocytes in the supraoptic nucleus lack glutamate uptake and receptor currents. Glia, 44: 102-110.

165. Makara J.K., Rappert A., Matthias K., Steinhäuser C., Spät A. and Kettenmann H. (2003) Astrocytes from mouse brain slices express ClC-2-mediated Cl- currents regulated during development and after injury. Mol. Cell Neurosci. 23: 521-530.

166. Malatesta P., Hack M.A., Hartfuss E., Kettenmann H., Klinkert W., Kirchhoff F. and Götz M. (2003) Neuronal or glial progeny: regional differences in radial glia fate. Neuron, 37: 751-764.

167. Matthias K., Kirchhoff F., Seifert G., Hüttmann K., Matyash M., Kettenmann H. and Steinhäuser C. (2003) Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J. Neurosci., 23: 1750-1758.

168. Peters O., Schipke C., Hashimoto Y. and Kettenmann H. (2003) Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex. J. Neurosci. 23: 9888-9896.

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169. Wehner T., Böntert M., Eyüpoglu I., Prass K., Prinz M., Fernández Klett F., Heinze M., Bechmann I., Nitsch R., Kirchhoff F., Kettenmann H., Dirnagl U. and Priller J. (2003) Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. J. Neurosci., 23: 5004-5011.

170. Angstwurm K., Hanisch U.-K., Gassemi T., Bille M.B., Prinz M., Dirnagl U., Kettenmann H. and Weber J.R. (2004) Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infect. Immun. 72: 3294-3298.

171. Hanisch U.-K., van Rossum D., Xie Y., Gast K., Misselwitz R., Auriola S., Goldsteins G., Koistinaho J., Kettenmann H. and Möller T. (2004) The microglia-activating potential of thrombin: the protease is not involved in the induction of proinflammatory cytokines and chemokines. J. Biol. Chem., 279(50): 51880-51887.

172. Kann O., Hoffmann A., Schumann R.R., Weber J.R., Kettenmann H. and Hanisch U.-K. (2004) The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level. J. Neurochem. 90: 513-525.

173. Kraft R., Grimm C., Grosse K., Hoffmann A., Sauerbruch S., Kettenmann H., Schultz G., Harteneck C. (2004) Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia. Am. J. Physiol. Cell. Physiol. 286: C129-C137.

174. Kuhn S.A., van Landeghem F.K.H., Zacharias R., Färber K., Rappert A., Pavlovic S., Hoffmann A., Nolte C. and Kettenmann H. (2004) Microglia express GABAB receptors to modulate interleukin release. Mol. Cell. Neurosci. 25: 312-322.

175. Nolte C., Gore A., Sekler I., Kresse W., Hershfinkel M., Hoffmann A., Kettenmann H. and Moran A. (2004) ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc. Glia 48: 145-155.

176. Rappert A., Bechmann I., Pivneva T., Mahlo J., Biber K., Nolte C., Kovac A.D., Gerard C., Boddeke H.W.G.M., Nitsch R. and Kettenmann H. (2004) CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J. Neurosci., 24: 8500-8509.

177. Wilhelm A., Volknandt W., Langer D., Nolte C., Kettenmann H. and Zimmermann H. (2004) Localization of SNARE proteins and secretory organelle proteins in astrocytes in vitro and in situ. Neurosci. Res. 48: 249-57.

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178. Färber, K. Pannasch U. and Kettenmann H. (2005) Dopamine and noradrenaline control distinct functions in rodent microglial cells, Mol. Cell Neurosci, 29:128-138.

179. Glass R., Synowitz M., Kronenberg G., Waelzlein JH, Markovic D., Wang LP., Gast D., Kiwit J., Kempermann G. and Kettenmann, H (2005) Glioblastoma-Induced Attraction of Endogenous Neural Precursor Cells Is Associated with Improved Survival, J. Neurosci., 25:2637-

2646.

180. Heidemann A. C., Schipke C. G., Kettenmann H. (2005) Extracellular application of nicotinic Acid adenine dinucleotide phosphate induces Ca2+ signaling in astrocytes in situ, J. Biol. Chem., 280: 35630-35640.

181. Höltje M., Hoffmann A., Hofmann F., Mucke C., Große G., Rooijen N. van, Kettenmann H., Just I. and Ahnert-Hilger G. (2005) The role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing, J. Neurochem. 95:1237-48.

182. Holtkamp N., Afanasieva A., Elstner A., Landeghem F. K. H. van, Könneker M., Kuhn S. A., Kettenmann H. and Deimling A. von (2005) Brain slice invasion model reveals genes differentially regulated in glioma invasion, Biochem. Biophys. Res. Commun. 336:1227-1233.

183. Jabs R., Pivneva T., Hüttmann K., Wyczynski A., Nolte C., Kettenmann H. and Steinhäuser C. (2005) Synaptic transmission onto hippocampal glial cells with hGFAP promoter activity, J. Cell Sci, 118:3791-3803.

184. Kresse W., Sekler I., Hoffmann A., Nolte C., Peters O. H., Moran A. and Kettenmann H. (2005) Zinc ions are endogenous modulators of neurotransmitter stimulated capacitative Ca2+ entry in both cultured and in situ mouse astrocytes. Eur. J. Neurosci, 21: 1626-1634.

185. Kronenberg G., Wang L.-P., Synowitz M., Gertz K., Katchanov J., Harms R. G. C., Kempermann G., Kettenmann H. and Endres M. (2005) Nestin-expressing cells adopt a complex electrophysiological phenotype following mild ischemic episode. J. Cerebral Blood Flow Metabolism, 25:1613-1624.

186. Markovic D., Glass R., Synowitz, M. and Kettenmann H. (2005) Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2, J. Neuropath. Experimental Neurology, 64: 754-762.

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187. Rose C., Kresse W. and Kettenmann H. (2005) Acut insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes: An effect of pH, J. Biol. Chem., 280:20937 – 20944.

188. Shukla, V, . H. Zimmermann, L. Wang, H. Kettenmann, S. Raab, K. Hammer, J. Sévigny, S. C. Robson and N. Braun (2005) Functional Expression of the Ecto-ATPase NTPDase2 and of Nucleotide Receptors by Neuronal Progenitor Cells in the Adult Murine Hippocampus, J. Neurosci. Res., 80:600-619.

189. Wang L.-P., Kempermann G. and Kettenmann H. (2005) A subpopulation of precursor cells in the mouse dentate gyrus receives synaptic GABAergic input. Mol. Cell Neurosci, 29:181-189.

190. Haas B., Schipke C. G., Peters O., Söhl G., Willecke K. and Kettenmann H. (2006) Activity-dependent ATP-waves in the Mouse Neocortex are Independent from Astrocytic Calcium Waves.Cereb Cortex, 16:237-46.

191. Pannasch U., Färber K., Nolte C., Blonski M., Yan Chiu S., Messing A. and Kettenmann H. (2006) The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia. MCN 33:401-411.

192. Sliwa M., Markovic D., Gabrusiewicz K., Synowitz M., Glass R., Zawadzka M., Wesolowska A., Kettenmann H., and Kaminska B. (2006) The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporine A. Brain, 130:476-489

193. Steiner B., Klempin F., Wang L., Kott M., Kettenmann H., and Kempermann G. (2006) Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis, Glia 54:805-814.

194. Synowitz M., Glass R., Faerber K, Markovic D, Kronenberg G., Herrmann K., Schnermann J., Nolte C., van Rooijen N., Kiwit J., and Kettenmann H. (2006) A1 Adenosine Receptors in Microglia Control Glioblastoma-Host Interaction. Cancer Res 66: 8550-8557.

195. Babu H, Cheung G, Kettenmann H, Palmer TD, Kempermann G. (2007) Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS ONE. 2:e388.

196. Ifuku M., Färber, K., Okuno Y., Yamakawa Y, Miyamoto T, Nolte C., Merrino V. F., Kita S., Iwamoto T., Komuro I., Wang B., Cheung G., Ishikawa E., Ooboshi H., Bader M., Wada K., Kettenmann H. and Noda M. (2007) Bradykinin-Induced Microglial Migration Mediated by B1-

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Bradykinin Receptors Depends on Ca2+ Influx via Reverse-Mode Activity of the Na+/Ca2+

Exchanger, J Neurosci. 27:13065-13073.

197. Kirischuk S., Kettenmann H. and Verkhratsky A. (2007) Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflugers Arch.454: 245-252.

198. Kronenberg G, Wang LP, Geraerts M, Babu H, Synowitz M, Vicens P, Lutsch G, Glass R, Yamaguchi M, Baekelandt V, Debyser Z, Kettenmann H, Kempermann G. (2007) Local origin and activity-dependent generation of nestin-expressing protoplasmic astrocytes in CA1. Brain Struct Funct. 212:19-35

199. Noda M, Kariura Y, Pannasch U, Nishikawa K, Wang L, Seike T, Ifuku M, Kosai Y, Wang B, Nolte C, Aoki S, Kettenmann H, Wada K. (2007) Neuroprotective role of bradykinin because of the attenuation of pro-inflammatory cytokine release from activated microglia.J Neurochem. 101:397-410.

200. Oertel J., Villmann C., Kettenmann H., Kirchhoff F. and Becker C. M. (2007) A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology: Assembly into Heteromeric receptor complexes. J. Biol. Chem. 282:2798-807.

201. Färber, K., Markworth, S., Pannasch, U., Prinz, V., Kronenberg, G., Gertz, K., Endres, M., Enjyoji, K., Robson, S. C. and Kettenmann H. (2008) The ectonucleotidase cd39/ENTPDase1 modulates purinergic-mediated microglial migration, Glia, 56:331-341.

202. Färber, K., Synowitz, M., Zahn, G., Vossmeyer, D., Stragies R., van Rooijen N. and Kettenmann H. (2008) An alpha5beta1 integrin inhibitor attenuates glioma growth. Mol Cell Neurosci.,39:579-585.

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203. Hoffmann A. , Hofmann F., Just I., Lehnardt S., Hanisch U. K., Brück W., Kettenmann H., Ahnert-Hilger G., Höltje M. (2008) Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia. Glia 56:1162-1175.

204. Morara S, Wang LP, Filippov V, Dickerson IM, Grohovaz F, Provini L, Kettenmann H. (2008) Calcitonin gene-related peptide (CGRP) triggers Ca responses in cultured astrocytes and in Bergmann glial cells from cerebellar slices. Eur J Neurosci. 28:2213-2220.

205. Pivneva T., Haas B., Reyes–Haro D., Laube G., Nolte C, Skibo G., and Kettenmann H. (2008) Store-operated Ca2+ entry in astrocytes: different spatial arrangement of endoplasmic reticulum explains functional diversity in vitro and in situ, Cell Calcium, 43:591-601.

206. Schipke C. G., Haas B. and Kettenmann H. (2008), Astrocytes Discriminate and Selectively

Respond to the Activity of a Subpopulation of Neurons within the Barrel Cortex. Cereb Cortex,

18:2450-2459.

207. Schipke C. G., Heidemann A., Skupin A., Peters O., Falcke M. and Kettenmann, H. (2008) Temperature and nitric oxide control spontaneous calcium transients in astrocytes, Cell Calcium 43: 285-295.

208. Skupin A., Kettenmann H., Winkler U., Wartenberg M., Sauer H., Tovey S. C. , Taylor C. W., and Falcke M. (2008)   By chance or by the clock: How does intracellular Ca2+ oscillate? Biophys. J. 94:2404-2411.

209. Waelzlein J.H., Synowitz M.., Engels B., Markovic D. S., Gabrusiewicz K., Nikolaev E. Yoshikawa K., Kaminska B., Kempermann G., Uckert W., Kaczmarek L., Kettenmann H., and Glass R. (2008), The anti-tumorigenic response of neural precursors depends on subventricular proliferation and age. Stem Cells 26:2945-2954.

210. Wang L.-P., Kronenberg G., Kempermann G., Endres M., and Kettenmann H. (2008) Mild brain ischemia induces unique physiological properties in striatal astrocytes, Glia 56:925-934.

211. Cheung G., Kann O., Kohsaka S., Faerber K., and Kettenmann H. (2009) GABAergic activities enhance macrophage inflammatory protein 1 alpha release from microglia (brain macrophages) in postnatal mouse brain. J Physiol. 587:753-768.

212. Chirasani S. R., Markovic D. S., Synowitz M., Eichler S.A., Wisniewski P., Kaminska B., Otto A., Wanker E., Schäfer M., Chiarugi P., Meier J.C., Kettenmann H., and Glass R. (2009)

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Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells. J Mol Med 87:153-167.

213. Färber K., Cheung G., Mitchell D., Wallis R., Weihe E., Schwaeble W., and Kettenmann H. (2009) C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation. J Neurosci Res. 87:644-652.

214. Ji S., Kronenberg G., Balkaya M., Färber K., Gertz K., Kettenmann H., and Endres M. (2009) Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome. Exp Neurol. 216:321-328.

215. Ye ZC, Oberheim N, Kettenmann H, Ransom BR. (2009) Pharmacological "cross-inhibition" of connexin hemichannels and swelling activated anion channels. Glia 57:258-269.

216. Markovic D.S., Vinnakota K., Chirasani S., Synowitz M., Raguet H., Stock K., Sliwa M., ,

Lehmann, S., Kälin R., van Rooijen N., Holmbeck K., Heppner F.L., Kiwit J., Matyash V.,

Lehnardt S., Kaminska B., Glass R., and Kettenmann H. (2009) Glioma induce and exploit

microglial MT1-MMP expression for tumor expansion, PNAS published online before print July

15, 2009, doi:10.1073/pnas.0804273106

Book Chapters and Review Articles

1. Wienrich M. and Kettenmann H. (1984) Intrazelluläre Farbstoffe zur Markierung einzelner neuraler Zellen in Kultur. Kontakte (Darmstadt) 3/84: 30-44.

2. Kettenmann H., Orkand R.K. and Schachner M. (1985) Potassium uptake mechanisms of cultured oligodendrocytes studied with ion-sensitive electrodes. In: Ion Measurements in Physiology and Medicine (Kessler M. et al., eds.) Springer Verlag, Berlin, Heidelberg, New York, Tokyo:194-198. 3. Kettenmann H. (1986) Oligodendrocytes control extracellular potassium by active uptake and spatial buffering. In: Advances in the Biosciences, Vol. 61: Dynamic Properties of Glial Cells II (Grisar T. et al., eds), Pergamon Press, Oxford, England, 155-163.

4. Schachner M., Kettenmann H., Sonnhof U., Backus K.H. and Sontheimer G. (1986) Elektrophysiologische Untersuchungen über Membranfunktionen der Neuroglia in Kultur. Ersatzmethoden zum Tierversuch. Bundesministerium für Forschung und Technologie, Bonn.

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5. Wienrich M. and Kettenmann H. (1986) Einsatz von Mikrocomputern im biomedizinischen Forschungslabor. Kontakte (Darmstadt). 1/86: 36-48.

6. Kettenmann H. (1987) Membrane conductance of oligodendrocytes is dominated by K+

channels. In: Functions of Neuroglia (Roitbak A. L., ed.), Metsniereba, Tblisi, UdSSR, 72-80.

7. Kettenmann H. (1987) Membraneigenschaften von Gliazellen. Physiologie aktuell, Bd. 3, G. Fischer Verlag, Stuttgart, F. R. G., 23-33.

8. Kettenmann H. (1988) Electrophysiological methods applied in nervous system cultures. In: Neuromethods Vol. 10, Neurochemistry VIII: `Brain Electrolytes and Water Spaces' (Boulton A. A., Baker G. B. and Walz W., eds.), Humana Press, Clifton, U. S. A., 493-544.

9. Kettenmann H., Backus K.H. and Schachner M. (1988) GABA receptors on cultured astrocytes. In: 'Glial Cell Receptors' (Kimelberg, ed.), Raven Press, New York, 95-106.

10. Kettenmann H., Backus K.H. and Schachner M. (1988) Glial GABA receptors. In: 'Biochemical Pathology of Astrocytes' (Norenberg M., Hertz L. and Schousboe A., eds.), A. Liss Inc., New York, 587-598.

11. Kettenmann H. (1990) Chloride channels and carriers in cultured glial cells. In: 'Chloride Channels and Carriers in Nerve, Muscle and Glial Cells' (Alvarez-Leefmans F. J. and Russel J., eds.), Plenum Press, New York, 193-208.

12. Kettenmann H., Backus K.H., Berger T.B., Sontheimer H. and Schachner M. (1990) Neurotransmitter receptors linked to ionic channels in cultured astrocytes: an electrophysiological approach. In: 'Differentiation and Functions of Glial Cells', (Levi G., ed.,) A. R. Liss, New York, 203-211.

13. Kettenmann H., Müller T. and Schachner M. (1990) Ersatz von Tierexperimenten in der Lehre - neurophysiologische Grundlagenkenntnisse aus dem Computer. Alternativen zum Tierexperiment, 13: 30-38.

14. Kettenmann H. (1991) Properties of (Gamma-Aminobutyric Acid)A receptors in glial cells. In: 'Transmitter Amino Acid Receptors: Structures, Transduction and Models for Drug Development', (Barnard E. A. and Costa E., eds.), Thieme Medical Publishers, New York, 37-50.

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15. Berger T. and Kettenmann H. (1992) Activation of neurokinin receptors in cultured astrocytes:

a role in K+ homeostasis by modulating K+ conductances? In: 'Epilepsy and Inhibition', (Speckmann E.-J. and Gutnick M.J., eds.), Urban & Schwarzenberg, München, Germany, 189-197.

16. Blankenfeld G. v. and Kettenmann H. (1992) Glutamate and GABA receptors in vertebrate glial cells. Mol. Neurobiol., 5: 31-41.

17. Kettenmann H., Blankenfeld G. v. and Trotter J. (1992) Physiological properties of oligodendrocytes during development. In: 'Glial-Neuronal Interactions', (Abbott N.J., Lieberman E.M. and Raff M.C., eds.), New York Acad. Sci., 64-77.

18. Kettenmann H., Banati R. and Walz W. (1993) Electrophysiological behavior of microglia. Glia, 7: 93-101.

19. Kimelberg H.K., O'Connor E.R. and Kettenmann H. (1993) Effects of Swelling on Glial Cell Function. In: 'Comparative and Environmental Physiology, Interaction of Cell Volume and Cell Function', 14, F. Lang and D. Häussinger (eds.), Springer Verlag, Heidelberg, 157-186.

20. Ransom B. R., Kettenmann H. and Sontheimer H. (1993) Characteristics of electrical coupling between mammalian glial cells studied in vitro. In: Functions of Neuroglia, Vol. 2, (Roitbak A., ed.), 50-56.

21. Steinhäuser C., Berger T., Jabs R., Frotscher M. and Kettenmann H. (1993) Voltage- and ligand-gated membrane currents of identified glial cells in the hippocampal slice. In: 'Slow Activity Changes in the Brain', (Haschke W. and Speckmann E.-J., eds.), Birkhäuser, Boston, 179-190.

22. Berger T., Müller T. and Kettenmann H. (1994) Developmental regulation of ion channels and receptors on glial cells. Perspect. Dev. Neurobiol. 4: 347-356.

23. Blankenfeld G. v., Enkvist K. and Kettenmann H. (1995) Gamma-aminobutyric acid and glutamate receptors. In: Neuroglia. Kettenmann, H. and Ransom, B.R., (eds.), Oxford University Press, New York, 335-345.

24. Kettenmann H. (1995) Bedeutung von Gliazellen für physiologische Vorgänge im zentralen Nervensystem. In: 'Aktuelle Neuropädiatrie', (Rating D., ed.), Ciba-Geigy Verlag, 47-56.

25. Kirchhoff F. and Kettenmann H. (1995) Glutamate receptors in glial cells. Verh. Dtsch. Zool. Ges. 88.2: 29-39.

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26. Müller T. and Kettenmann H. (1995) Physiology of Bergmann glial cells. Int. Rev. Neurobiol. 38: 341-359.

27. Patt S., Labrakakis C., Weydt P. and Kettenmann H. (1995) The physiological approach to neurooncology. J. Neuropathol. Exp. Neurology, Suppl. 42-43.

28. Kettenmann H., Faissner A. and Trotter J. (1996) Neuron-glia interactions in homeostasis and degeneration. In: 'Human Physiology' (Greger R. and Windhorst U., eds), Springer-Verlag, Heidelberg, 533-543.

29. Kettenmann H. (1996) Beyond the neuronal circuitry. Trends Neurosci. 19: 305-306.

30. Verkhratsky A. and Kettenmann H. (1996) Calcium signalling in glial cells. Trends Neurosci. 19: 346-352.

31. Kettenmann H. (1997) Alexander von Humboldt and the concept of animal electricity. Trends Neurosci. 20: 239-242.

32. Verkhratsky A., Orkand R.K. and Kettenmann H. (1998) Glial calcium: homeostasis and signaling function. Physiol. Rev. 78: 99-141.

33. Kettenmann H. (1999) Physiology of Glial Cells. Jasper’s Basic Mechanisms of the Epilepsies. In: Third Edition: Advances in Neurology, Vol 79 (Escueta, Wilson, Olsen, and Porter, eds.). Lippincott Williams & Wilkins, Philadelphia, 565-571.

34. Kettenmann H. (2002) Cellular components of neuroinflammation - an introduction. Ernst Schering Res Found Works:1-9

35. Biber K., Rappert A., Kettenmann H., Brouwer N., Copray S. C. V. M. and Boddeke H. W. G. M. (2002) Neuronal SLC (CCL21) expression: implications for the neuron-microglial signaling system. Ernst Schering Res Found Works: 45-60.

36. Kettenmann, H. and Schipke C. G. (2004) Calcium signaling in glia. In Glial/Neuronal Signaling, chapter 11.

37. Kettenmann H., and Ransom B. R. (2004) The concept of neuroglia: a historical perspective. In: Neuroglia, Kettenmann, H. and Ransom, B. R., (eds.), Oxford University Press, New York, 1-16.

38. Kettenmann, H. and Steinhäuser, C. (2004) Receptors for neurotranmitters and hormones. In:

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Neuroglia, Kettenmann, H. and Ransom, B.R., (eds.), Oxford University Press, New York, 131-145.

39. Schipke, C. G., and Kettenmann, H. (2004) Astrocyte responses to neuronal activity. Glia. 47: 226-32.

40. Marchetti, B., Kettenmann, H., and Streit, W. J. (2005) Glia–neuron crosstalk in neuroinflammation, neurodegeneration and neuroprotection: Introductory comments, Brain Res. Rev. 48:129– 132.

41. Färber K., and Kettenmann H. (2005) Physiology of microglial cells, Brain Res. Rev. 48: 133– 143.

42. Färber K, and Kettenmann H (2006) Purinergic signaling and microglia. Pflugers Arch. 452:615-621.

43. Färber, K., and Kettenmann H. (2006) Functional Role of Calcium Signals for Microglial Function, Glia 54:656-665.

44. Kettenmann H. (2006) Triggering the brain's pathologic sensor, Nat. Neurosci. 9: 1463-1464.

45. Noda M., Kettenmann H, Wada K. (2006) Anti-inflammatory effects of kinins via microglia in the central nervous system Biol Chem. 387:167-171.

46. Kettenmann H. (2007) The brain’s garbage men, Nature 446:987- 989.

47. Hanisch, U. K. and Kettenmann, H. (2007) Microglia – active sensor and versatile effector cells in the normal and pathologic brain, Nat. Neurosci. 10:1387 – 1394.

48. Pocock, J. M. and Kettenmann H. (2007) Neurotransmitter receptors on microglia, Trends Neurosci., 30:527-535

49. Kettenmann H and Verkhratsky A. (2008) Neuroglia: the 150 years after. Trends Neurosci., 31: 653-659

Scientific Books

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Kettenmann H. and Grantyn R. (eds.) (1992) Electrophysiological Methods for in Vitro Studies in Vertebrate Neurobiology. Wiley-Liss, New York.

Kettenmann H. and Ransom B. R. (eds.) (1995) Neuroglia. Oxford University Press. New-York.

Carter A. J. and Kettenmann H. (eds.) (1999) Cell Culture Models as Alternatives to Animal Experimentation for the Testing of Neuroprotective Compounds in Stroke Research. Practical Handbook of Methods. Forschungszentrum Jülich.

Kettenmann H. and Ransom B. R. (eds.) (2005) Neuroglia, Second edition. Oxford University Press. New-York.

Popular Science Books

Kettenmann H. and Rudolf W. (1998) Berliner Gehirne – Gehirne für Berlin (Brains of Berlin – Brains for Berlin) Fachhochschule für Technik und Wirtschaft/Max-Delbrück-Centrum für Molekulare Medizin Berlin.

Bielka H. and Kettenmann H. (1999) Galerie Berliner Naturwissenschaftler und Ärzte. Ausgewählte Biographien – Gallery of Berlin Scientists. Selected Biographies. Max Delbrück Center for Moecular Medicine (MDC) Berlin.

Kettenmann H., Zaun J. and Korthals S. (eds) (2001) Unsichtbar – Sichtbar – Durchschaut. Das Mikroskop als Werkzeug des Lebenswissenschaflers. Max-Delbrück-Centrum für Molekulare Medizin Berlin.

Kettenmann H. and Gibson M. (eds) (2001) Kosmos Gehirn. Neurowissenschaftliche Gesellschaft und Bundessministerium für Bildung und Forschung (BMBF) Berlin/Bonn.

Bielka H. and Kettenmann H. (2005) Berliner Medizingeschichte. Ausgewählte Biographien – Medical History of Berlin. Selected biographies. 2. enlarged edition. Max Delbrück Center for Molecular Medicine (MDC) Berlin.

Manuscripts in press

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Peters O.., Schipke C.G., Philipps A., Haas B., Pannasch U., Wang L.P., Benedetti B., Kingston

A.E., and Kettenmann H, (2009) Astrocyte function is modified by Alzheimer`s disease-like

pathology in aged mice. J. of Alzheimers Dis., in press

Müller J., Reyes-Haro D., Pivneva T., Nolte C., Schaette R., Lübke J., and Kettenmann H. (2009)

The principal neurons of the medial nucleus of the trapezoid body and NG2+ glial cells receive

coordinated excitatory synaptic input. J Gen. Physiol., in press

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