QUICK FACTS: PERIPHERAL ARTERIAL DISEASE (PAD) Peripheral Arterial Disease (PAD) is a disorder that affects arteries supplying blood to the body, most commonly restricting blood flow to the legs [2]. Arteries are blood vessels that carry blood away from the heart to the rest of the body [2]. DEVELOPING PAD The disease develops when cholesterol levels and scar tissue build up in the arteries, causing them to narrow. [1] ATHEROSCLEROSIS When plaque, the buildup of cholesterol and scar tissue, blocks the lining of the artery, it results in poor blood flow, commonly called atherosclerosis. [1] Plaque ARMS & LEGS The restricted blood flow limits blood supply, oxygen, and nutrients from flowing to the arms and legs. [2] References: Lutonix 035 Patient Guide: Treatment of PAD: http://loveyourlimbs.com/wp-content/uploads/2015/07/Lutonix- 035-Patient-Guide-S120586-r1.pdf Mohler, Emile R., and Alan T. Hirsch. 100 Questions & Answers about Peripheral Artery Disease (PAD). Sudbury, MA: Jones and Bartlett, 2010. Print. BPV/GBPV/0916/0011 1. 2.