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Quality Control Concerns for New Generations of CT, MRI, & PET David W. Jordan, Ph.D. Sr. Medical Physicist , UH Case Medical Center Clinical Assistant Professor, CWRU
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Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

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Page 1: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Quality Control Concerns for New Generations of CT, MRI, & PET

David W. Jordan, Ph.D.Sr. Medical Physicist , UH Case Medical Center

Clinical Assistant Professor, CWRU

Page 2: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Disclosures

• No financial disclosures or industry relationships

• Member of organizations discussed:– AAPM TG-126 (PET)– AAPM WGMRQA (MRI)

Page 3: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Objectives

• Understand the typical elements of a QC program for CT, MRI, and PET equipment.

• Anticipate the QC challenges created by new imaging technology advances.

Page 4: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Outline

• Overview of current QC procedures for CT, MRI, and PET.

• Discuss new CT technology : wide/cone beams and iterative reconstruction

• Discuss new MRI technology: parallel imaging and massively multichannel coils

• Discuss new PET technology: time of flight and alternatives to PMT detectors

Page 5: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

QC Perspectives

• Medical Physicist

• Imaging Technologist

Page 6: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

QC Goals

• Obtain data to characterize performance (and dose)

• Obtain data to optimize performance• Monitor constancy of function/performance

Page 7: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

“Meta” QC:What is the Quality of your Quality Control?

• Does each test contribute to– characterization, and/or– optimization, and/or– constancy?

Page 8: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

“Meta” QC:What is the Quality of your Quality Control?

• Is each test:– Clinically relevant?– Feasible? (time, cost)– Sensitive?– Specific?

Page 9: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

“Meta” QC:What is the Quality of your Quality Control?

• Is each/every test mandated by:– ACR?– AAPM TG # such and such?– Joint Commission?– ACRIN / CRO?– Ohio Department of Health?– Etc.?

Page 10: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT

Page 11: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Current QC: CT

• QC phantom measurements:– CT # accuracy/linearity– Uniformity– Noise / CNR / SNR– High & low contrast– Scanner alignment

Page 12: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Current QC: CT

• Dose: CTDI100

• 16 & 32 cm dia. cylinders (10-15 cm thick)

• Measure scanner output

Page 13: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT Advances: Iterative Recon

M.J. Willemink et al., “Iterative reconstruction techniques for computed tomography Part 1: technical principles.,” Eur. Radiol. 23(6), 1623–31 (2013).

Page 14: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT IR QC Challenges

• IR techniques manipulate image noise

• Radiologists report “texture” concerns with reconstructed images

• Details of reconstruction proprietary– Is CT # manipulated / better / worse?

Page 15: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT IR QC: What and How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 16: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT Advances: Wide Beams

© Xoran Technologies, http://xorantech.com/minicat-technical-specifications/

© Toshiba Medical Systems, http://www.toshiba-medical.eu/upload/TMSE_CT/Aquilion_QDE_L.jpg?epslanguage=en

100-mm CTDI “pencil” chamber

Page 17: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Wide Beam QC Challenges• CTDI100 inadequate for dose (scanner

output) measurements• Proposed alternatives (TG-111)

cumbersome:– Large/long phantom– Non-standard equipment & metrics

• TG 200 working on feasibleimplementation

Page 18: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

C. Descamps, M. Gonzalez, E. Garrigo, A. Germanier, and D. Venencia, “Measurements of the dose delivered during CT exams using AAPM Task Group Report No. 111.,” J. Appl. Clin. Med. Phys. 13(6), 3934 (2012).

Page 19: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Wide/Cone Beam CT Dose: How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 20: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

CT Coming Attractions…

• CT performance assessment including iterative reconstructions:– AAPM Task Group

223– Established 2012– Ehsan Samei, Chair

• Development of wide/cone beam dosimetry:– AAPM Task Group

200– Established 2010– Donovan Bakalyar,

Chair

Page 21: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

MRI

Page 22: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Current QC: MRI• Magnet homogeneity• Scanner performance

– Slice position/thickness

– Geometric accuracy– Resolution– Artifacts

• Performance of all individual coils– SNR, uniformity

Page 23: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

MRI Advances: Parallel Imaging

R. Hashemi, W.G. Bradley, and C.J. Lisanti, MRI: The Basics (Lippincott Williams & Wilkins, 2010).

Page 24: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Parallel MRI QC Challenges

Page 25: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Parallel MRI: What/How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 26: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

MRI Advances: Coils

T. Niendorf et al., “Progress and promises of human cardiac magnetic resonance at ultrahigh fields: a physics perspective.,” J. Magn. Reson. 229, 208–22 (2013).

Page 27: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Coil QC Challenges

• State of the art coil arrays have up to 128 channels– Many MORE individual elements in some

arrays!• Existing methods:

– Simple/aggregated scan may miss problems– Thorough testing can take hours per coil,

typical scanner has 10-20 coils

Page 28: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

MRI Coil Arrays: What/How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 29: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

MRI Coming Attractions…

• Parallel Imaging Technology & QC:– AAPM Task Group

118– Established 2005– Nathan Yanasak,

Chair

• RF Coil QC (and other topics):– AAPM WG on MR

Testing and QA– Established 2005– Joseph Och, Chair

Page 30: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

PET

Page 31: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Current QC: PET• Phantom images

– SUV accuracy– Contrast cold/ ”warm”

/hot objects– “Resolution”

• Count rate response vs. activity

• Sensitivity• Spatial resolution• Corrections

Page 32: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

PET Advances: Time of Flight

• Diagram of line of response vs “segment”of response

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TOF-PET: What/How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 34: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

PET Advances: New Detectors

http://staff.science.uva.nl/~zoon/sms/SMS.html

Page 35: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Non-PMT Detector QC Challenges

• Air-cooled arrays’ performance depends on ambient temperature

• Detection efficiency and speed affect sensitivity, count rate performance

• Enable or require use of different scintillators?

• Effect of timing resolution?

Page 36: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Post-PMT PET: What/How To Test?

• Characterization?• Optimization?• Constancy?

• Clinically relevant?• Feasible?• Sensitive?• Specific?

Page 37: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

PET Coming Attractions…

• PET-CT Acceptance Testing & QC:– AAPM Task Group

126– Established 2005– Osama Mawlawi,

Chair

Page 38: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Review of Objectives

• New technology developments:– CT: iterative recon, wide beams, dose

reduction technology– MRI: parallel imaging and multichannel coils– PET: time of flight and non-PMT detectors

• New technologies may or may not be adequately addressed by existing QC methods

Page 39: Quality Control Concerns for New Generations of CT, MRI…chapter.aapm.org/pennohio/2013FallSympPresentations/SI5_David... · Quality Control Concerns for New Generations of CT, MRI,

Thank you!

• Questions?