QOL Minimally Important Difference H MID H · QOL 0Û o %Ê'2FøMID %Ê'2Fþ vG QOL/PRO %Ê'2 >Ì10 QOL %Ê'2 +«>Ì Ë PRO Fþ MFôFøFçFöF¸ QOL 0Û o& Fþ6ä$Î QOL 0Û oFþ)
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• Palliative care is an approach that improves the quality of life (QOL) of patients and their families facing the problem associated with life-threatening illness.
QOL (WHO, 2002, National Cancer Control Programmes
Policies and managerial guideline 2nd edition)
• Outcomes of palliative care can be obtained by measuring patient QOL.
QOL
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Purpose
To estimate MID for EORTC QLQ-C15-PAL scores for the assessment of QOL of palliative care patients.
QOL EORTC QLQ-C15-PAL(European Organisation for Research and Treatment of Cancer Quality of Life Core 15 Palliative) MID
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29
First survey 1 Second survey 2
2w
EORTC QLQ-C15-PAL
Clinical information*
EORTC QLQ-C15-PAL
GRS
Clinical information*
“What do patients themselves think of the
difference between the first and second time
they participated in the QOL survey?”
QOL
Measurement method
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EORTC QLQ-C15-PAL
• EORTC QLQ-C15-PAL was developed for palliative care patients by taking
the 30-item QLQ-C30 as a base and reducing the number of questions to
15 items.
EORTC QLQ-C15-PAL QLQ-C30
30 15 15
(Groenvold M, et al. Eur J Cancer, 2006)
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Results Flowchart for Patient Selection
Request participation
n=257
Number of patients enrolled in
the 1st QOL survey
1 QOL
n=240
2nd QOL survey and
GRS survey completed
MID analysis subjects 2
n=181
Refusal n=12
Worsened condition n=3
Transfer n=2
Death n=20
Worsened condition n=25 No follow-up due to transfer