ProBiotics for Health – “Our Private Garden Tract”

8/3/2019 ProBiotics for Health – “Our Private Garden Tract”

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Probiotics for Health“Our Private Garden Tract”

Meeting of

The Japanese College of IV Therapy

Tokyo, Japan February 2009

Bradford S. Weeks, MD

www.weeksmd.com

*Slides with (SFO) are from my friend Stephen Olmstead, M.D.*

http://www.weeksmd.com/

http://www.weeksmd.com/



BSW (c) 2009



BSW (c) 2009



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The Intestinal Microbiota Organ (SFO)

• 10 meters long (average adult)

• Weighs 1.5 Kg

• Metabolic activity rivals liver

• Regulates Immune function

• Digests foods

• Creates vitamins• Modulates acid-base

Human Colon

air contrast barium enema



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The Human Intestinal Microbiota (SFO)

Our best guess…

• 100 trillion microorganisms

• 10 x number human cells

• >100 x number human genes

• >1000 genera

• >500 cultured species

• Dominated by 2 divisions Firmicutes and Bacteroidetes

• 99% anaerobic?



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Gaston Naessens

The Somotid – pleomorphism

www.whale.to/cancer/naessens.html

Louis Pasteur

“Germs cause disease”

Prof. Antoine Béchamp

“The Terrain rules.”



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Naessens:

The Somatid cycle

Bacteria become yeast

which in turn becomebacteria etc.

The environment

created the germs.



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Germ Theory vs. Terrain

Pasteur on his death bed: “Le terrain, c’est tout.”

“The Terrain is all.”

Why cows? Why no cows?



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Germ Theory vs. Terrain

Pasteur: Germs are present, immutable, responsible for disease.

Rx: anti-biotics and vaccines

Béchamp : Germs are pleomorphic and their presence or absencedepends upon the environment, the terrain.

Rx: change the terrain

Bernard the role of "milieu" or environment changes the mix of microorganisms as the body moves from alkaline pH to acidic pH.



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References and Further Reading Ethel Douglas: Bechamp or Pasteur (later published as Pasteur Exposed ) –

http://www.healthresearchbooks.com/pages/book_detail.php?pid=1102 R B Perason: The Dream and Lie of Louis Pasteur –

http://www.sumeria.net/dream.html

The Lost History of Medicine

http://www.mnwelldir.org/docs/terrain/lost_history_of_medicine.htm

Breaking the Vicious Cycle

Elaine Gottschall

Sick and Tired?

Robert Young

http://www.healthresearchbooks.com/pages/book_detail.php?pid=1102





http://www.healthresearchbooks.com/pages/book_detail.php?pid=1102



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How big is the surface area of the GI tract?

… imagine flattening out all the villi to account for that surface areas…



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The surface area of the GI tract = size of a tennis court?



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Same number of intestinal villi as blades of grass?



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Bigger!

The Football Field WithinPer Dr. Stephen Olmstead, M.D.



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Where is my GI tract?

It is OUTSIDE the human body.

All the microorganisms live outside of us.

If they entered within us, into out bloodstream or tissues = death .

Probiotics and antibiotics function

outside the human body.



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The Doughnut Metaphor

The hole is our

intestinal lumen.Man as doughnut.



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Doughnut Metaphor

But remember:

The finger is

never “inside”

the doughnut.

Things can pass

through man

and things pass

through doughnuts.



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The most dangerous daily task!

Eating!

What would happen if you IV’d the food you ate thismorning for breakfast? Phlebitis? Or Anaphylaxis and

death!

Eating food requires chewing, digestive enzymes and apro-biotically balanced gastro-intestinal tract to

“de-animate” it, reduce it to common nutritional currency

and render it safe for absorption .



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Self- vs Non Self

You are what you eat… (if digestion is weak).

Frank PurdueChicken

Football playerBeef



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Where is your “immune system”

It wraps around your gut like an insulating blanket

and addresses anything that leaks through

threatening to enter your privated blood stream.





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Cross Reactivity and Dysbiosis

Cross-reactivity between therheumatoid arthritis-

associated motif EQKRAAand structurally relatedsequences found in Proteusmirabilis.

Infection and immunity

1999;67(6):2769-75.

Tiwana H; Wilson C; Alvarez A;

Abuknesha R; Bansal S; Ebringer A



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History of Probiotics

10,000 BC fermented beverages (mead)

3,000 BC yogurt

Hippocrates (460-370 BCE)

Sour milk for GI disorders

Pliny the Elder (23-79 CE)

Health benefits of sour milk

All native cultures eat a raw or fermented food

Natto

Fermented soy

Kombucha tea



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Probiotics – Clinical Applications (SFO)

The Prolongation of Life 1907

Eli Metchnikoff

Nobel laureate 19081848-1916

“The dependence of the intestinal

microbes on the food makes it possible to

adopt measures to modify the flora in ourbodies and replace the harmful microbes

with useful microbes.”

“Starve the Yeast over 3 days.”



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Lactobacillus Benefits (SFO)

• Digest & metabolize proteins & carbohydrates

• Synthesize B vitamins & vitamin K

• Catabolize bile salts

• Enhance innate & acquired immunity

• Inhibit proinflammatory mediators

• Antimicrobial activities against array of pathogens: Pseudomonas,

E. coli, Staph. aureus, Salmonella, Shigella, Candida & H. pylori

• Reduces GI concentrations of carcinogenic enzymes

• Antagonizes rotavirus & C. difficile

• Suppresses enterohemorrhagic E. coli internalization

• Inhibits EHEC intestinal cell adherence & invasion• Decreases production of inflammatory mediators

• Supports intestinal barrier function

• Reduces translocation of gut flora



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Bifidobacterium Characteristics (SFO)

• Gram-positive, non-sporulating rods or Y-shaped

• Strictly anaerobic & fastidious

• All metabolize lactose

• Ferment non-digestible oligosaccharides

• Synthesize B vitamins & vitamin K

• Enhance innate & acquired immunity

• Inhibit proinflammatory mediators

• Inhibit pathogens via organic acids & H2O2

• Inhibits enterotoxigenic E. coli receptor binding & translocation• Inhibits Clostridium proliferation

• Enhances GI sIgA response to dietary antigens

• Modulates cytokine response to respiratory antigens



Probioic Deficiency Syndrome (“PDS”) Etiology:Non-breast fed infantsBreast fed infants from dysbiotic mothers

People taking antibotics early and often

People who don’t eat real and raw and fermented foods

People eating dairy (antacid effect)

Some elderly people (loss of digestive forces)

Clinical Signs and Symtoms:Bloating

Gas , burping, flatulence

GERD (gastro esophageal reflux disease)

ObesityInsomnia

Depression

Poly-inflammatory diseases

Yeast over growth

Diarrhea or constipation



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•Non-pathogenic yeast

•Heat & pH resistant

•Transient GI species

•Active ingredient in medicinal teas

•Increases brush border enzyme activities•Secretes leucine aminopeptidase;

supports against dietary protein allergies

•Increases short-chain fatty acid concentrations

•Increases intestinal sIgA; crypt cell Ig receptors

•Protease that inhibits C. difficle toxins A & B

•Antogonizes Gram (-), Candida & Entamoeba hystolytica

Saccharomyces boulardii (SFO)



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Probiotic Dosing (SFO)

• May need to start low , go slow

Acid stable technology - 50-90% viability

• Unprotected probiotics - ≤10% viability

• Doses in the millions CFU - may not be beneficial

• Trend is for 100s of billion CFU

• 109-11 CFU tolerated by immunosuppressed patients• 110 billion CFU/Kg tolerated by infants

• Products available with 850 billion CFU/dose



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Probiotic Dosing (SFO)

With or without food?

Stomach pH: fasting: 1.5with food: 2 – 3

Transit time: 30 min – 1 hr

Take your probiotics with food.



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Probiotics & Antibiotics

•Antibiotics from Latin meaning: “against life”

•Yes. They do save lives.

•But the ancients taught …

“All illness begins in the gut.”

•Antibiotics cause dysbiosis (disorder biology) in gut.

•Antibiotics create chronic and acute illnesses.

•Probiotics do not interfere with antibiotics if taken 2 hrs

before or after the antibiotic dose



Probiotics - Documented Uses (SFO)

• Antibiotic-associated diarrhea

• C. difficile-associated diarrhea

• Community acquired diarrhea

• Traveler’s diarrhea

• Inflammatory bowel disease

• Irritable bowel disease

• Vaginal dysbiosis

• Urinary tract infections• Allergies, atopic dermatitis, eczema

• Lactose intolerance

• Hyperlipidemia



Summary and Recommendation

1. “All disease begins in the gut.”

2. “We” (cells with our DNA) are outnumbered 10:1

3. When “I” reach for sugar (saki, dessert, ) it may not be

“me”, but rather the yeast which needs to be fed their

diet of choice: fast burning carbohydrates!

4. When high-quality probiotics are used, far ranging

benefits accrue in all physiological systems; 5. Not all probiotics are good quality - so buy the best!

6. Treat the gut first , the rest is less complicated.



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“He’s got guts.”

“He has courage” not, “He is obese!”

means



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THE END

I thank you again

for your kind attention

and

invite any questions.



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Please feel free toEMAIL ME

withquestions or comments.

[email protected] 360-341-2303

mailto:[email protected]

mailto:[email protected]

ProBiotics for Health – “Our Private Garden Tract”

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