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Treadmill Stress Testingfor the Primary Care Physician
Francis G. OConnor, MD, FACSM
Primary Care Sports Medicine
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O!ecti"es
#e"ie$ essential %&ercise Test Terminology
Descrie the Performance of the %&ercise Stress Test
Disc'ss (nterpretation of the %&ercise Stress Test
Disc'ss Special Considerations in Athletes
#e"ie$ (ndications for )$o'ld*e+ Athletes
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oring-.....
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Gonzales
Dietche Playford
Howe
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%&ercise Test Terminology
The %lectrocardiogram
O/ma&
M%Ts Myocardial O&ygen
Cons'mption
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The %lectrocardiogram
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The %lectrocardiographic #esponse
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0hat isO/ma&-
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Ma&imal O&ygen 1pta2e
3O/ma&4
Greatest amo'nt of o&ygen an indi"id'al 'tili5es $ith
ma&imal e&ercise 3ml O/ per 2ilogram per min'te4
)Gold Standard+ for cardiorespiratory fitness Fic2 %6'ation
O/ma& 7 38#ma& & Sma&4 & 3CaO/ma& * C"O/ma&4
Diff iF(C= %>1AT(O?
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VO2max= (HRmax X SVmax X (!aO2max " !#O2max
Genetic Factors 38eart Si5e4
Conditioning FactorsContractility9Afterload9Preload
Disease Factors
0all Motion9entric'lar F&n al"eStenosis or #eg'rgitation
S2eletal M'scles
:Aeroic %n5ymes
:Fier Type
:M'scle Disease
Capillary Density
PaO/
8g ; 1AT(O?
3//@ * Age4
Sin's ?ode Dysf'nction
Dr'gs 3e.g.,B* loc2ers4
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M%TS$he %&$
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Metaolic %6'i"alents 3M%Ts4
M%T 7 B. ml O/ per 2ilogram of ody$eight per min'te
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Key MET Values (part 1)
1 MET = "Basal" = 3.5 ml O2 /Kg/min
2 METs = 2 mph on level
4 METs = 4 mph on level
< 5METs = Poor prognosis i < !5
limi# imme$ia#e pos# M%
&os# o 'asi& aivi#ies o $ail( living
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Key MET Values (part 2)
1) METs = *s goo$ a prognosis +i#h me$i&al#herap( as ,*B-
13 METs = E&ellen# prognosis regar$less o o#hereer&ise responses
1! METs = *ero'i& mas#er a#hle#e
2) METs = Ooh lah lah *ero'i& a#hle#e
)
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Myocardial (MO2)
Acc'rate meas'rement re6'ires cardiaccatheteri5ation
,oronar( 0lo+ ,oronar( a O2 $ieren&e
all Tension Pressre olme ,on#raili#(-#ro6e or6 789
-(s#oli& Bloo$ Pressre 78 *ngina an$ -T :epression sall( o&&rs a# same:o'le Pro$ in an in$ivi$al;; :ire rela#ionship #o O2 is al#ere$ '( 'e#a'lo&6ers #raining...
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Myocardial O&ygen Cons'mption
(ndirectly meas'red as the )Do'le Prod'ct+
)Do'le Prod'ct+ 7 8# & systolic lood press're A normal "al'e is greater than /@,@@@ /,@@@
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O!ecti"es
#e"ie$ essential %&ercise Test Terminology
Descrie the Performance of the %&ercise Stress Test
Disc'ss (nterpretation of the %&ercise Stress Test
Disc'ss Special Considerations in Athletes
#e"ie$ (ndications for )$o'ld*e+ Athletes
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Performance of the %&ercise
Stress Test
(ndications9Contraindications
#'nning the %&ercise Test
Physician #esponsiilities
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ACSMs G'idelines
for %&ercise Testing and Prescription
ACSM. Eippincott, 0illiams 0il2ins
th %dition /@@@
di i f i i
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(ndications for %&ercise Testing
Class (H Conditions for $hich there is e"idence and9or general
agreement that a gi"en proced're or treatment is 'sef'l and effecti"e Class ((H Conditions for $hich there is conflicting e"idence and9or a
di"ergence of opinion ao't the 'sef'lness9efficacy of a proced're or
treatment. (( aH $eight of e"idence is in fa"or of 'sef'lness9efficacy.
(( H 'sef'lness is less $ell estalished y the e"idence.
Class (((H Conditions for $hich there is e"idence and9or general
agreement that the proced're9treatment is not 'sef'l9effecti"e and in
some cases may e harmf'l.
Cl ( ( di ti f P f i
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Class ( (ndications for Performing an
%&ercise Test
Diagnosis of CAD in ad'lts $ith intermediatepretestproaility of disease
Assessfunctional capacityandprognosisof patients $ithH
Known CAD Recent uncomplicated myocardial infarction
%"al'ate symptoms of rec'rrent, e&ercise*ind'ced arrhythmias
Cl (( ( di ti f Pe f i
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Class (( (ndications for Performing
an %&ercise Test
To e"al'ate asymptomatic men IJ@ and $omen I@$hoH
are in"ol"ed in special, high ris2 occ'pationsK
plan to start a "igoro's e&ercise programK
ha"e m'ltiple cardiac ris2 factors. To assist in the diagnosis of CAD in ad'lt patients $ith a
high or lo$ pretest proaility of disease.
To e"al'ate patients $ith a Class ( indication $ho ha"e
aseline electrocardiographic changes.
Class ((( (ndications for Performing
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Class ((( (ndications for Performing
an %&ercise Test
#o'tine screening of asymptomatic men or $omen.
To e"al'ate men or $omen $ith a history of chest
discomfort not tho'ght to e of cardiac origin.
To e"al'ate patients $ith simple PCs on a resting%CG $ith no other e"idence of CAD.
To assist in the diagnosis of CAD in patients $ith
e"idence of E or 0P0 on a resting %CG.
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Pre Test Probability of Coronary Disease by
Symptoms, Gener an !"e
!"e Gener Typi#al$Definite!n"ina Pe#toris
!typi#al$Probable!n"ina Pe#toris
%on&!n"inal
C'est Pain
!symptomati#
3)3 Males %n#erme$ia#e %n#erme$ia#e lo+ o+
5)5 0emales %n#erme$ia#e %n#erme$ia#e >o+ 2er( lo+
!)! Males 7igh %n#erme$ia#e %n#erme$ia#e >o+
!)! 0emales 7igh %n#erme$ia#e %n#erme$ia#e >o+
7igh = ?) %n#erme$ia#e = 1)) >o+ = o+ =
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Contraindications to GLT TestingH
Asol'te #ecent ac'te M(
1nstale angina
entric'lar tachycardia Dissecting aortic
ane'rysm
Ac'te C8F
Se"ere aortic stenosis
Acti"e myocarditis
Thromophleitis orintracardiac thromi
#ecent p'lmonary emol's
Ac'te infection
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Contraindications to GLT TestingH
#elati"e 1ncontrolled se"ere
hypertension
Moderate aortic stenosis Se"ere s'aortic stenosis
S'pra"entric'lar dysrhythmias
entric'lar ane'rysm
Comple& "entric'lar ectopy
Cardiomyopathy
1ncontrolled metaolic disea #ec'rrent infectio's disease
Complicated pregnancy
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So 0hat Do o' DoN.
B yo female $ith ris2 factors and as6'irrelly storyN.
Comparison of Tests for Diagnosis
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Comparison of Tests for Diagnosisof CAD
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0hich Protocol-
ast Ma!ority 3/QR4 'se #1C%
So, $hy not yo'-
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How to read an Exercise ECG
Good sin prep!" isoelectric line#ot one $eatT%ree consistent complexesA&erages can %elp
Gar$age in' gar$age ot%y watc% dring reco&ery*
+ymptom +ign -imited Testing Endpoints
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+ymptom,+ign -imited Testing Endpoints.%en to stop/
Dyspnea, fati"ue, #'est pain
Systoli# bloo pressure rop
ECG&&ST #'an"es, arr'yt'mias
P'ysi#ian !ssessment
or" S#ale (1 or "reater)
!ro$lems wit% Age !redicted Maximal Heart
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!ro$lems wit% Age,!redicted Maximal Heart"ate
hi&h 8egression 0ormla@ 2AA .A *ge9 Big s&a##er aron$ #he regression line
poor &orrela#ion C).4 #o ).!D
One -: is pls/mins 12 'pm
* per&en# vale #arge# +ill 'e maimal or some an$s'ma or o#hers
,onon$e$ '( Be#a Blo&6ers
Borg s&ale is 'e##er or evala#ing Eor# Targe# 7ear# 8a#e $oes have a pla&e as an %n$i&a#oro Eor# or a$ea&( o #es#
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M%TS$he %&$
Heart "ate Drop in "eco&ery &s
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Heart "ate Drop in "eco&ery &sMETs
01 to 03increase in survival per MET
METS can be increased by 23by atraining program
What about Heart Rate Recovery???
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8eart #ate #eco"ery and Treadmill%&ercise Score as Predictors of Mortality
in Patients #eferred for %&ercise %CG
?ishime %O, et alH AMA, Septemer /@, /@@@.
o /J, ?o , /@@@.
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Follo$ing the GLT, patients $al2ed for / min'tes at . mphand at a grade of /.R.
8eart rate reco"ery $as the difference in heart rate at pea2
e&ercise and one min'te into reco"eryK /9min or less $as
considered anormal. JJ patients $ere follo$ed for a median of yearsK /@ R had
anormal heart rate reco"eryK they represented R of deaths
"s. /RK ha5ard ratio of J..
8eart rate reco"ery is an independent predictor of mortality.
+% ld H t " t D i
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+%old Heart "ate Drop in"eco&ery $e added to ET*
Long known as a indicator o itness! perhapsbetter or assessing physical activity than
METsRecently ound to be a predictor o prognosisater clinical treadmill testing
"oes not predict angiographic #$"
Studies to date have used all%cause mortalityand ailed to censor
Heart "ate Drop in "eco&ery
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Heart "ate Drop in "eco&ery
&robably not more predictive than "ukeTreadmill Score or METs
Studies including censoring and #'mortality needed
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O!ecti"es
#e"ie$ essential %&ercise Test Terminology
Descrie the Performance of the %&ercise Stress Test
Disc'ss (nterpretation of the %&ercise Stress Test Disc'ss Special Considerations in Athletes
#e"ie$ (ndications for )$o'ld*e+ Athletes
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(nterpretation of the %&ercise Stress Test
%'st !ontain ollowin) &lements*
%&ercise Capacity
8emodynamic
Clinical
%lectrocardiographic
Optional Other St'ffN..
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Positi"e "s S'ggesti"e
ST Depression or 1mm at
60msec
1!"mm at#0msec
ST $le%ation 1mm at 60msec
ST Depression or 0!" & 1mm
at 60msec
0!' & 1!"mm at#0msec
ST $le%ation 0!" ( 1mm at
60msec
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?egati"e "s (nconcl'si"e
A)o%e criteria notmet and pte*ercised to at least#"+ ,-.R
-t did not reac/#"+ ,-.R )utno e%idence ofisc/emia 2&2loc3er445
"()E Treadmill Score or
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"()E Treadmill Score orStable #$"
METs % * + ,mm E%- ST "epression. %
/ + ,Treadmill $ngina -nde0.
1111112omogram1111111
E% = Eer&ise %n$&e$
Du3e Treadmill Score une%en lines elderly45
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3ut #an &hysicians do as well as the
Scores? 4*/ patients % clinical5ETT reports
Sent to // e0pert cardiologists6 /7cardiologists and 87 internists
Scores did better than all three but wasmost similar to the e0perts
! i
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O!ecti"es
#e"ie$ essential %&ercise Test Terminology
Descrie the Performance of the %&ercise Stress Test
Disc'ss (nterpretation of the %&ercise Stress Test Disc'ss Special Considerations in Athletes
#e"ie$ (ndications for )$o'ld*e+ Athletes
Special Considerations inA hl
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Athletes
(ndications
Athletic 8eart
Syndrome
Test (nterpretation
O! i
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O!ecti"es
#e"ie$ essential %&ercise Test Terminology
Descrie the Performance of the %&ercise Stress Test
Disc'ss (nterpretation of the %&ercise Stress Test Disc'ss Special Considerations in Athletes
#e"ie$ (ndications for )$o'ld*e+ Athletes
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Does the patient need a GLT-
Contro"ersial
ACSM* M'st e ale to disting'ishH
Moderate "s. "igoro's e&ercise Apparently healthy "s. higher ris2
Older "s. yo'nger
ACSM #ecommendations for Medical %&amination and
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ACSM #ecommendations for Medical %&amination and
%&ercise Testing Prior to Participation
RecommendRecommendVi)oro's&xercise
Recommend+ot
+ecessary%oderate&xercise
Hi)h Ris,%od Ris,-ow Ris,
+ot+ecessary
+ot+ecessary
ACSM (nitial #is2 Stratification y Age
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y g
and Cardiac #is2
%oderate Ris, )Older+ indi"id'als / ris2 factors
Cardiac #is2 Factors* Cigarette smo2ing
* Fam 8&. of early CAD
* EDE IB@4* 8ypertension
* (mpaired fasting gl'c
3I@mg9dE4
*
Oesity 3M( IB@4* Sedentary lifestyle
Cardiac #is2 Factors* Cigarette smo2ing
* Fam 8&. of early CAD
*
EDE IB@4* 8ypertension
* (mpaired fasting gl'c
3I@mg9dE4
* Oesity 3M( IB@4
* Sedentary lifestyle
)Positi"e+ #is2 FactorH 8igh ser'm 8DE 3I@4)Positi"e+ #is2 FactorH)Positi"e+ #is2 FactorH
-ow Ris, Men J, 0omen ?o cardiac symptoms ris2 factor
ACSM (nitial #is2 Stratification y Age
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y g
and Cardiac #is2
-ow Ris, Men J, 0omen ?o cardiac symptoms ris2 factor
%oderate Ris, )Older+ indi"id'als / ris2 factors
Hi)h Ris, Signs or Symptoms of cardiac d5 =no$n cardiac, p'lmonary or metaolic
3DM4 disease.
Signs9S&. C Disease*Chest pain or anginal e6'i"
*Dyspnea $9 mild e&ertion
*Di55iness or syncope
*Orthopnea9P?D
*An2le edema
*Palpitations or tachycardia
*(ntermittent cla'dication
*Fatig'e $9 normal acti"ities
Signs9S&. C Disease*Chest pain or anginal e6'i"
*Dyspnea $9 mild e&ertion
*Di55iness or syncope
*Orthopnea9P?D
*An2le edema
*Palpitations or tachycardia
*(ntermittent cla'dication
*Fatig'e $9 normal acti"ities
.ho +eeds a GX$/
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.ho +eeds a GX$/
+ot+ecessary
+ot+ecessary
Athlete $ith 2no$n CAD
Anyone $ith symptoms of CAD
Moderate ris2 patient for "igoro's e&erciseAnyone $ith 2no$n medical disease
Athlete $ith 2no$n CAD
Anyone $ith symptoms of CAD
Moderate ris2 patient for "igoro'se&erciseAnyone $ith 2no$n medical disease
-ow Ris, %od Ris, Hi)h Ris,
%oderate&xercise
+ot+ecessary
Recommend
Vi)oro's&xercise
Recommend Recommend
>'estions---
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>'estions---
!hris !hris $h dd
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!hris0Don1t !all
%e -t
!hris0Pa3a$eet
!hris04t1s %ya'lt
$hadde's
late's
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