PDQ-Evidence. What is PDQ-Evidence? PDQ (“pretty darn quick”)-Evidence facilitates rapid access to the best available evidence for decisions about health.

PDQ-Evidence

What is PDQ-Evidence?

• PDQ (“pretty darn quick”)-Evidence facilitates rapid access to the best available evidence for decisions about health systems and population health

It is a version of Epistemonikos database for Health systems and population health evidence

Epistemonikos is a non-for-profit organisation based in Santiago, Chile

Our mission is “to bring high quality information closer to health decision making through the use of information technologies”

What evidence?

Systematic reviewsOverviews of reviewsHigh-quality structured summariesPrimary studies included in systematic reviews

The problem: information overload

The challenge: to separate the wheat from the chaff

23,000,000 records only in PubMed

• 0,25% are systematic reviews

Our goal

TO AGGREGATE ALL THE RELEVANT HEALTH EVIDENCE (FOR DECISION-MAKING IN HEALTH SYSTEMS AND POPULATION HEALTH) INTO A SINGLE DATABASE.

A little bit more about PDQ-Evidence: Search strategy

PDQ-Evidence was developed and is maintained by systematically searching PubMed and other databases for relevant systematic reviews and overviews of reviews.

Where do we search• Cochrane database of systematic reviews (CDSR)• Database of Abstracts of Reviews of Effectiveness (DARE)• Health Technology Assessment Database• PubMed• LILACS• SUPPORT Summaries• EPPI-Centre Evidence Library• 3ie Systematic Reviews and Policy Briefs• WHO Database• Campbell Library• SURE policy briefs• European Observatory on Health Systems and Policies• DFID• NICE public health guidelines and systematic reviews• Guide to Community Preventive Services• CADTH Rx for Change• McMaster Plus KT+• McMaster Health Forum Evidence Briefs

Systematic reviews (SR) at the centre

• The average SR takes about 1-year of work

• We rescue that effort by storing identified studies

From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centre

Where do we search? 20 databases

Systematic reviews (SR) at the centre

• The average SR takes about 1-year of work

• We rescue that effort by storing identified studies

From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centre

All that effort into a single database

Where do we search? 20 databases

Relations are stored in the database

Unique feature• One of PDQ-Evidence unique features is that it connects

systematic reviews and their included studies. • This makes possible to navigate between primary studies and

reviews

Multilingual

• Spanish• Portuguese• French

Filters

Advanced search

• For systematic searches• E.g. systematic reviews

Grey literature / unpublished

• Our search process implies searching for published literatureAnd then going to:

- the list of studies included in reviews- the list of reviews included in overviews and policy briefs

INDEPENDENT OF- WHERE IS PUBLISHED (OR IF IT IS PUBLISHED AT ALL)

- LANGUAGE

Unique feature: matrix of evidence• One of PDQ-Evidence unique features is that it connects

systematic reviews and their included studies. • This makes possible to navigate between primary studies and

reviews, but also allows clustering systematic reviews based on the primary studies they have in common.

• The concept of ‘Systematic reviews sharing included studies’ is a proxy of ‘systematic reviews answering a similar question’

Matrix of evidence

How do we feed PDQ-Evidence?

• Combination of machine technology and human collaboration~ 10 Software engineers (for 5 years)~ 400 collaborators (Epistemonikos)

Automatic search and upload

Selection of actual systematic reviews by a network of collaborators

Extraction of the studies included in the systematic review

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The numbers

• 30,000 records• 3,300 systematic reviews

Conclusions

• One-stop shop for evidence• Multilingual database• User friendly• Relation between articles answering a similar

question• Visualisation of ‘all the evidence’ for a specific

question

Let’ see some examples

Many thanks!!

Contact us:[email protected] [email protected]

…or follow us in your preferred language:English: @epistemonikosSpanish: @epistemonikosEsGerman: @epistemonikosDeFrench: @epistemonikosFr

….also in Facebook and google+

Portuguese: @epistemonikosPtItalian: @epistemonikosItArabic: @epistemonikosArDutch: @epistemonikosNlChinese: @epistemonikosZh

Gabriel RadaAssociate Professor, Department of Internal Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

Director of the Evidence-Based Healthcare Program (Chilean Cochrane Centre), Pontificia Universidad Católica de Chile, Santiago, Chile

Co-director of the Southern American Branch of the Iberoamerican Cochrane Centre

Member of GRADE working group

Co-founder, President and CEO of Epistemonikos Foundation

More details here: about.mee-mail: [email protected]: @radagabriel