Pat Mammae

7/24/2019 Pat Mammae

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PATOLOGI

KELENJAR MAMMAE


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FIBROCYSTIC DISEASE

1. Hiperplasia Du!us "# Hiperplasia i$!ra%u!us

# Papil&'a!&sis i$!ra%u!us

# Re%upliasi %a$ pl&ri(erasi ele$)ar

# Per!a'*a+a$ s!r&'a

# Jari$,a$ ia! 'e$ea$ %u!usse+i$,,a lu'e$ +ila$,- !i$,,al*e*erapa epi!el %ia$!ara s!r&'apa%a! sler&sis$, a%e$&sis/


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0. Hiperplasia Jari$,a$ Pe$,ia!

# Ta'pa per!u'*u+a$ )ari$,a$pe$,ia! &la,e$ a$, +&'&,e$se+i$,,a 'e$ea$ )ari$,a$ ia!i$!erl&*uler a$, 'is&'a!&sa.

# Mu$,i$ aa$ !a'pa ,a'*ara$ %ari%u!us %a$ ele$)ar a$, a!r&(iare$a pe$ea$a$ a$, *erle*i+a$%ari )ari$,a$


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2. Pe'*e$!ua$ Kis!a elai$a$ is!i/# Ta'pa *a$,u$a$ is!a a$, !er*e$!u

%ari %u!us.# Pa%a is!a a$, *eruura$le*ar3*esar-epi!el !a'pa 'e$ipis-a%a$,4a%a$, a!r&(is.

# Pa%a is!a a$, e5il- epi!el$a u*&i%sa'pai !&ra- seri$, *er!u'pu4!u'pu-se+i$,,a aa$ !a'pa s!ru!ur papiler

# Mu$,i$ %i%apa!i )u,a is!a a$, %ilapisi&le+ *e*erapa lapisa$ sel4sel a$,*eruura$ *esar- p&li,&$al- 'e$,a$%u$,si!&plas'a a$, ,ra$uler- e&si$&(ili-%e$,a$ i$!i *ula!- e5il- %a$+iperr&'a!i.


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# S!r&'a !er%iri %ari )ari$,a$ ia! pa%a!.

# Pa%a )ari$,a$ sei!ar is!a seri$,%i%apa!a$ li'(&si! *ua$ ra%a$,/


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FIBROCYSTIC DISEASE


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FIBROADENOMA MAMMAE

1. Ba,ia$ a$, *erasal %ari )ari$,a$ ia! a$,*erupa pr&li(erasi (i*r&*las %a$ sera*u! &la,e$-'e$u$)ua$ ,a'*ara$ 'is&'a!&us %i sei!ar*a,ia$ a$, *erasal %ari epi!el ele$)ar.

0. His!&l&,is !er%apa! 0 ,a'*ara$ "

Fi*ria%e$&'a peria$aliuler "

Per!u'*u+a$ a$, *erasal %ari epi!el ele$)arle*i+ %&'i$a$ se+i$,,a !a'pa ,a'*ara$ sara$,!u'&r 'e'*e$!u ele')ar4ele$)ar *er*e$!u

*ula! a!au l&$)&$, a$, %ilapisi epi!el selapis a!au*e*erapa lapis- %ielili$,i per!u'*u+a$ a$,*erasal %ari )ari$,a$ ia!.


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Fi*r&a%e$&'a i$!raa$aliuler

Per!u'*u+a$ a$, *erasal %ari )ari$,a$ia! le*i+ %&'i$a$- se+i$,,a &'p&$e$a$, *erasal %ari epi!el ele$)ar !a'pa'erupaa$ sara$,4sara$, sel !u'&r a$,

!ersusu$ 'e'e$)a$, a!au !i%a*era!ura$- %e$,a$ lu'e$ ele$)ar se'pi!a!au !i%a a%a sa'a seali.

2. Se'ua sel4sel !u'&r !i%a 'e$u$)ua$!a$%a e,a$asa$


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FIBROADENOMA MAMMAE


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TUMOR PHYLLODESProliferasi duktus & stroma.

Makras sangat besar.

da ! " benigna# borderline& maligna.


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PAGET6S DISEASE1. Kuli! pa%a area a$, !ere$a 'e$u$)ua$

a%a$a pe$e*ala$ +iper!r&(i epi%er'is se*elu'!er)a%i$a ulserasi.

0. Ta'pa sel4sel !u'&r ,a$as arsi$&'ai$!ra%u!al pa%a 'uara %u!us esre!&rius pa%auli! 'a''ae- %ia$!ara$a !er%apa! *e*erapa

sel i$(il!ra!i(.Kara!eris!i " s!ru!ur sel !u'&r a$, %ise*u!Sel PAGETS "Sel *esar %e$,a$ i$!i +iperr&'asi-a$a i$!ie5il4pi$&!i- %isei!ar i$!i !er%apa! ,a'*ara$+al& a$, %ise*a*a$ &le+ %e,e$erasi +i%r&pi*all&$i$, %e,e$era!i&$/.Ga'*ara* !s* pali$, *a$a %i%apa!i pa%a lapisa$*asalis $a'u$ %apa! 'e$e'*us e seluru+ lapisa$

epi%er'is.


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!. La$isan di ba%a e$itel menun'ukkan infiltrasi

limfosit dan sel $lasma.

(. Pada stadium )ang tela lan'ut akan tam$ak

gambaran ulserasi $ada e$idermis


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PAGET6S DISEASE


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KARSINOMA D7KT7S MAMMAE

NON INFILTRATIF1. Ta'pa ,a'*ara$ %u!us 'a''ae a$, *ula! %a$l&$)&$,.

0. Pr&li(erasi a$aplas!i epi!el %u!us a$,'e$e*a*a$ ,a'*ara$ epi!el %u!us *erlapis4lapis- %apa! 'e'e$u+i %a$ 'e$u'*a! %u!us-a$, !er%iri a!as el&'p& sel4sel *esar-p&li'&r(- si!&plas'a )er$i+ %e$,a$ $uleus *esar+iperr&'asi %a$ seri$, !a'pa a%a$a 'i!&sispa!&l&,is.

2. Kel&'p&4el&'p& sel !u&'r seri$, !a'pa*er*e$!u a5i$er a!au papiler %a$ *elu''e$e'*us 'e'*ra$a *asalis.

8. Pa%a *a,ia$ se$!ral %u!us %i)u'pai $er&sis sel4sel !u'&r


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KARSINOMA D7KT7S MAMMAENON INFILTRATIF


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*RS+,OM S-H+RRHOUS MMME

1. Sara$,4sara$, e5il %ari sel4sel !u'&r,a$as a$, 'e'*e$!u *a$,u$a$ ele$)ara!au !erlepas %ia$!ara s!r&'a )ari$,a$ ia!

a$, pa%a! %a$ luas.0. Sel4sel !u'&r *e$!u p&li,&$al a!au *ula!-

*esar u$i(&r'- i$!i +iperr&'asi- 'i!&sispa!&l&,is.

2. Ba,ia$ !epi !u'&r a%a$,4a%a$,'e$e*u e )ari$,a$ le'a- peri9asuler-peri$eural- %a$ pe'*ulu+ %ara+.


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*RS+,OM S-H+RRHOUS MMME


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*RS+,OM MEDULLRE MMME

1. Ger&'*&la$ sel4sel !u'&r a$, !er%iri %ari sel4sel *esar- *erel&'p&- *e$!u p&li,&$al-si!&plas'a *as&(il- p&li'&r(- i$!i +iperr&'asi

%a$ *a$a 'i!&sis pa!&l&,is.0. Kel&'p& sel !u'&r !ersusu$ !i%a !era!ur-

!i%a )elas 'e'*e$!u *a$,u$a$ ele$)ar a!aupapiler.

2. Ka%a$,4a%a$, %i!e'ua$ se*ua$ li'(&si! a$,'e$&l& pa%a s!r&'a a$, *iasa$a !ipis a!au%i %ala' ,er&'*&la$ sel.


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*RS+,OM MEDULLRE MMME


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