IOVS 17-21832-R2 Accepted version Optical Coherence Tomography Analysis Based Prediction of Humphrey 24-2 Visual Field Thresholds in Patients with Glaucoma [OCT based prediction of visual fields] Precis (35 words) We validated the performance of prediction of individual Humphrey 24-2 visual field thresholds from 9-field OCT analysis on patients with early to severe glaucoma. Zhihui Guo 6 Young H. Kwon, MD, PhD 2,3 Kyungmoo Lee, PhD 1 Kai Wang, PhD 4 Andreas Wahle 1 Wallace L.M. Alward 2,3 John H. Fingert 2,3 Daniel I. Bettis 3 Chris A. Johnson, PhD 3 Mona K. Garvin, PhD 1,5 Milan Sonka, PhD 1,3 Michael D. Abramoff, MD, PhD 1,2,3,5,6* 1 Department of Electrical and Computer Engineering, University of Iowa 2 Stephen A. Wynn Institute for Vision Research, University of Iowa 3 Department of Ophthalmology and Visual Sciences, University of Iowa 4 Department of Biostatistics, College of Public Health, University of Iowa 5 Iowa City VA Health Care System 6 Department of Biomedical Engineering, University of Iowa *Corresponding author: [email protected], The University of Iowa, 11205 Pomerantz Family Pavilion, Iowa City, IA 52242, USA, phone: 319-384-5833. Financial support: This work was partially supported by NIH grants R01 EY019112, R01 EY018853 and R01 EB004640; the Department of Veterans Affairs; the Marlene S. and Leonard A. Hadley Glaucoma Research Fund.
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IOVS 17-21832-R2 Accepted version
Optical Coherence Tomography Analysis Based Prediction of
Humphrey 24-2 Visual Field Thresholds in Patients with Glaucoma
[OCT based prediction of visual fields]
Precis (35 words) We validated the performance of prediction of individual Humphrey 24-2 visual field
thresholds from 9-field OCT analysis on patients with early to severe glaucoma. Zhihui Guo6
Young H. Kwon, MD, PhD2,3 Kyungmoo Lee, PhD1
Kai Wang, PhD4 Andreas Wahle1 Wallace L.M. Alward2,3 John H. Fingert2,3 Daniel I. Bettis3 Chris A. Johnson, PhD3 Mona K. Garvin, PhD1,5 Milan Sonka, PhD1,3 Michael D. Abramoff, MD, PhD1,2,3,5,6*
1 Department of Electrical and Computer Engineering, University of Iowa 2 Stephen A. Wynn Institute for Vision Research, University of Iowa 3 Department of Ophthalmology and Visual Sciences, University of Iowa 4 Department of Biostatistics, College of Public Health, University of Iowa 5 Iowa City VA Health Care System 6 Department of Biomedical Engineering, University of Iowa *Corresponding author: [email protected], The University of Iowa, 11205 Pomerantz Family Pavilion, Iowa City, IA 52242, USA, phone: 319-384-5833.
Financial support: This work was partially supported by NIH grants R01 EY019112, R01 EY018853 and R01
EB004640; the Department of Veterans Affairs; the Marlene S. and Leonard A. Hadley Glaucoma Research Fund.
Dr. Kwon is supported by the Clifford M. & Ruth M. Altermatt Professorship. Dr. Alward is supported by the
Frederick C. Blodi Chair. Dr. Abramoff is supported by the Robert C. Watzke MD Professorship.
Table 4. The comparison of the bias and the width of LoA between RGC-AC optimized model and repeat HVF at different sensitivities across 52 sectors.
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