M AY 2013 The Neuroscience Letter n° 180 The LARC-Neurosciences network 1 researchers in the Neuroscience-field. Acvies will consist of short talks, a lab tour, panel debates, art exhibion, and informaon displays. Topics include: the ageing brain, the link between rugby and brain cancer, the blood-brain barrier, special talks around demena, how the brain has evolved, and much more. To find out more and register, please go to: hp://www.port.ac.uk/aboutus/ ageingnetwork/events/ The octadecaneuropepde ODN prevents 6- hydroxydopamine-induced apoptosis of cerebellar granule neurons through a PKC-MAPK-dependent pathway. H. Kaddour, Y. Hamdi, D. Vaudry, M. Basille, L. Desrues, J. Leprince, H. Castel, H. Vaudry, M.C. Tonon, M. Amri, O. Masmoudi-Kouki. In this arcle published in J. Neurochem. (2013;125:620-633), researchers from the University of Tunis and Inserm Unit 982 show that the ODN-pepde, an endozepine produced by astroglial cells in the CNS, has a neuroprotecve effect in vitro towards the toxicity of 6-hydroxydopamine. This an-apoptoc acon involves a receptor which is pharmacologically dinsnct from classical benzodiazepine receptors and the acvaon of the PLC/PKC/MAK pathway. These studies suggest that the ODN-pepde could be the basis for the development of derivaves selecvely mimicking its neuroprotecve acvity. Spao-temporal characterizaon of the pleiotro- phinergic system in mouse cerebellum: Evidence for its key role during ontogenesis. M. Basille-Dugay, M.M. Hamza, C. Tassery, B. Parent, E. Raoult, M. Bé- nard, R. Raisman-Vozari, D. Vaudry, D.C. Burel. In this arcle, to be published in Exp. Neurol. (2013, in press, doi:pii: S0014-4886(13) 00057-5), researchers from INSERM Unit 982 describe the spaotemporal characteri- zaon of pleiotrophin and of its receptors in the mice cerebellum, and demonstrate that this system contri- butes to key steps of the ontogenesis of the cerebellum. In parcular, pleiotrophin can control morphogenesis of Purkinje cells and regulate migraon of granule cells during cerebellar development. Furthermore, this molecule contributes to the forma- on of the perineuronal networks in the adult cerebellum, suggesng that it contributes to neuronal plascity. The 17 th Annual meeng of the LARC- Neuroscience Network will take place on Friday 25 th October 2013 in Rouen, organized by Dr David VAUDRY (Inserm U982), Pr Serguei FETISSOS (Inserm U1073) and colleagues. The conference will be held at the H 2 O, a building dedicated to the promoon of science, and located Quai de Boiguilbert along the Seine river. The program will feature three plenary lectures given by Pr Denis BURDAKOV (MRC Naonal Instute for Medical Research, London, United Kingdom) with a presentaon entled « Pepdergic neurons and brain state control », Pr Henry MARKRAM (Brain Mind Instute, Lausanne, Switzerland) with a presentaon entled « The Human Brain Project » and Pr Stuart ALLAN (University of Manchester, Manches- ter, United Kingdom) with a presentaon entled « Inflammaon and stroke: it's not all in the brain ». The meeng will also include twelve oral presen- taons given by some of the leading young researchers from the LARC member instuons. There will also be a poster display session and a lunchme networking opportunity. Prizes will be awarded for the best oral and poster presentaons. Thanks to the support from the Interreg IVA 2 Seas TC2N project, the registraon is free but the number of parcipants is limited to 200. For more informaon and registraon, visit: hp://larc-neurosciences.org/ registraon Registraon and abstract submission for the 39 th Symposium of the French Society of Neuroendocrinology (SNE) have been extended unl May 17 th . To find out more and register, please go to: hp://sne2013.univ-rouen.fr 17 th Annual meeting of the LARC- Neuroscience network Publicaons 39 th Symposium of the SNE The University of Portsmouth Ageing Network (UPAN) is hosng a series of free public events in May for the « European Month of the Brain » to inform on the latest discoveries of its Month of the Brain