Mediquiz , a Medical trivia Quiz

MediQuiz

Venue : Thrissur medical collegeDate : July 26 , 2017

Quiz Master : Jim Jacob Roy

Quiz Master’s Advice…

ROUND 1

RULES

• 12 Questions

• 10 points for each question unless stated otherwise

• Pounce /Bounce format (+10 /-10)

Q1.• ………. is a brass

instrument that was used in the ancient Roman army , for the announcement of night watches, to summon soldiers by means of the special signals and to give orders .

• The instrument is the ancestor of the trumpet.

• The person who blew this instrument was called a X

• Which structure in the human body is named after X ?

And The Answer Is….

BUCCINATOR

Q2.• Gabrielle .……... was one of the most important anatomists and physicians of the sixteenth

century .

• His work dealt mainly with the anatomy of the head. He added much to what was known before about the internal ear . He was the first to point out the connection between the mastoid cells and the middle ear . His description of the lacrimal ducts in the eye was a marked advance on those of his predecessors and he also gave a detailed account of the ethmoid bone and its cells in the nose .

• He studied the reproductive organs in both sexes the first to describe a condom (in his writings, a linen sheath wrapped around the penis), and he advocated the use of such sheaths to prevent syphilis .

• 2 structures in the human body are named after him – one is in the ear & the other in the reproductive system .

• Name both


FALLOPIAN CANAL FOR FACIAL NERVE ; FALLOPIAN TUBE

Q3. Name the 6th layer of cornea (between corneal stroma & descemet’smembrane) proposed by Harminder Singh X & his team in 2013


DUA’S LAYER

Q4.• Leonardo da Vinci depicted this entity correctly and it

remained that way for centuries until 1885, when Sir Frederick Treves' findings presented it in a different manner – this description was believed to be true till late when Prof.J Calvin Coffey (Professor of surgery , University of Limerick’s Graduate Entry Medical school ,Ireland ) in his research published otherwise .

•What is this entity being talked about ?


MESENTERY

Q5.• The ulnar canal or ulnar tunnel is a semi-rigid longitudinal canal in the

wrist that allows passage of the ulnar artery and ulnar nerve into the hand.

• The roof of the canal is made up of the superficial palmar carpal ligament, while the deeper flexor retinaculum and hypothenar muscles comprise the floor. The space is medially bounded by the pisiform and pisohamateligament more proximally, and laterally bounded by the hook of the hamate more distally.

• The canal was first described by a French surgeon Jean Casimir Félix X in 1861 ,and so the canal is also called the X canal

• X is ?


GUYON’S CANAL

• Guyon’s tunnel syndrome :

• local trauma, fractures, ganglion cysts, and classically avid cyclists who experience repetitive trauma against bicycle handlebars

Q6 . Below is a list of ? X & Y ?

X

2 associated with the head of the 1st

metacarpal ( in the adductor pollicis & flexor pollicis brevis tendons)

2 associated with the head of the 1st metatarsal (in the tendon of flexor halluc-is brevis)

Y


TYPICAL SESAMOID BONES IN THE HUMAN BODY PATELLA ; PISISFORM

Q7.FITB• …………. are a group of naturally occurring polysaccharides produced by

many types of plants .

• They belong to a class of dietary fibers known as fructans.

• ............ is used by some plants as a means of storing energy and is typically found in roots or rhizomes.

• This polysaccharide and its analog sinistrin are used to help measure kidney function by determining the glomerular filtration rate

• It is not secreted or reabsorbed in any appreciable amount at the nephron , allowing GFR to be calculated. However, due to clinical limitations, .......... and sinistrin, although characterised by better handling features, are rarely used for this purpose and creatininevalues are the standard for determining an approximate GFR.


INULIN

Q8. For the estimation of blood sugar level ,the collection bottles are coated with X which is an inhibitor of the glycolytic enzyme Y . Identify X &Y


ENOLASE , FLOURIDE

Q9.FITB• Global Public Health Days offer great potential to raise awareness and understanding

about health issues and mobilize support for action, from the local community to the international stage.

• WHO focuses particular attention on the 7 days and 1 week that WHO Member States have mandated as "official" global public health days. These are:

• World TB Day, 24 March

• World Health Day, 7 April

• World Immunization Week, last week of April

• World Malaria Day, 25 April

• World No Tobacco Day ,31 May

• World Blood Donor Day, 14 June

• X ?

• World AIDS Day, 1 December


WORLD HEPATITIS DAY

• JULY 28TH

Q10.• The Gift of Pain is a book written by Dr.Paul Brand &

Philip Yancey .

• Dr.Paul Brand was a son of missionary parents in Southern India . He himself was a dedicated missionary & an extraordinary gifted orthopaedic surgeon who

“ straightened crooked hands & unravelled the riddle of X “

• As a pioneer in tendon transfer techniques , he estabalished & practiced initially in New Life Centre & Schieffelin X Research Centre ,Karigiri ,South India .

• He saw pain as vital for the preservation of healthy tissue in anyone leading a normal life. He goes on to question the pursuit of pleasure in Western society and offers practical ways to ameliorate the effects of pain.

• What was the disease in which he much concentrated upon ?


HANSEN’S DISEASE

Q11.• This protein was first identified when a routine pre operative sample of a

37 year old railroad brakeman John ……. was found to have prolonged clotting time in test tubes ,even though the patient had no hemorrhagic symptoms .

• He was then examined by the hematologist Oscar Ratnoff ,who found that he lacked a previously unidentified clotting factor .

• He found that the deficiency is autosomal recessive in inheritance .

• Name the protein .


HAGEMAN FACTOR

Q12. Why were these 2 hospitals in news recently ?


INDIA’S 1ST UTERINE TRANSPLANTATION IN INDIA

WEIGHT REDUCTION SURGERY FOR EMAN AHMAD

ROUND 2

RULES

• Written Round

• Alphabets from the A to H

• Each answer carries 5 points

• No negative points

A German physician A gave up his medical practice as he was dissatisfied with the state of medicine in his time , and made his living from writing & translating books

My sense of duty would not easily allow me to treat the unknown pathological state of my suffering brethren with these unknown medicines. The thought of becoming in this way a murderer or malefactor towards the life of my fellow human beings was most terrible to me, so terrible and disturbing that I wholly gave up my practice in the first years of my married life and occupied myself solely with chemistry and writing.

• A came to read about B , a plant the bark of which has some remedial powers to cure the disease C

• The plant B was named so by Carl Linnaeus ( a Swedish Botanist ,often referred to as The Father of Taxonomy) after a Spanish town .

• The 4th Count of this town was the Viceroy of Peru , and his wife Ana de Osorio suffered from C , and was cured after taking the medicine prepared from B .

• She took B back to Europe on her return journey .( However ,this was found to be historically incorrect by later

reseachers )

• D & E are the two active alkaloids contained in the bark of B used medically

• D was once commonly used to treat C .• D also played a significant role in the colonization of

Africa by Europeans. • D had been said to be the prime reason Africa ceased to

be known as the "white man's grave".• D is on WHO’s List of Essential Medicines in a Health

System .

• E is a stereoisomer of D ,and is a Class 1 anti arrythmicagent .

• ………….. annua is a common herb found in many parts of the world, and has been used by Chinese herbalists for more than 2000 years in the treatment of C .

• In 1967, a plant screening research program, under the name Project 523, was set up by the People's Liberation Army of China to find an adequate treatment for C

• In the course of this research, F discovered G in the leaves of …….. Annua .

• The genus name ………….. is derived from a Greek goddess and, more specifically, may have been named after Queen ………. II of Caria, a botanist and medical researcher in the fourth century BCE .

• F was awarded Nobel Prize in Medicine for this discovery

• A believed that other astringent substances are not effective against C and began to research B's effect on the human body by self-application.

• Noting that the drug induced C-like symptoms in himself, he concluded that it would do so in any healthy individual.

• This led him to postulate a healing principle: "that which can produce a set of symptoms in a healthy individual, can treat a sick individual who is manifesting a similar set of symptoms.“

• This is one of the basic principles of H ,a branch of medicine


ANSWERS

• A - SAMUEL HAHNEMAN• B – CINCHONA• C – MALARIA• D – QUININE• E – QUINIDINE• F – YOUYOU TU• G – ARTEMESININ• H – HOMEOPATHY

ROUND 3

RULES

• 12 questions

• 10 points for a question unless specified otherwise

• Pounce / Bounce Format (+10/-10)

Q1.• Fransisco Jose de Goya was a Spanish romantic painter – he

is considered as the most important Spanish artist of late 18th and early 19th centuries .

• The image on the next slide is that of a painting by FransiscoJose de Goya drawn between 1802 & 1812 .

• A title given to this painting is ‘Curacion del Garrottillo’ , which is not correct according to researchers .

• The original title of the painting is ‘El Lazarillo de Tormes’ ,inspired from a book of the same title from the 1500s in which a blind man asks his helper boy to cook sausage for him, the boy steals it and the blind man tries to get it out from his mouth .

• What was the reason for the title ‘Curacion del Garrottillo’ ?

• A middle aged man with a black moustache , his eyes nearly closed , trying to grasp something out of the boy’s mouth using his 2 fingers of the right hand .

THE MAN TRYING TO REMOVE DIPHTHERIA MEMBRANE FROM THE THROAT

Q2.FITB

• The cause of death of the legendary Jamaican singer Bob Marley is considered to be …………

• The 1st attention to the illness was made when he injured his injured his right great toe during a soccer game in Paris in 1977

• The toe nail became partially detached & painful – he admitted to his manger that the toe had been injured before and the wound was on & off for years .A skin biopsy was done – the doctors advised amputation of the toe to prevent spread of the disease.But he was against it (because of certain religious beliefs .However he permitted the excision of some part of the toe & a skin graft was put .

• But his condition worsened and he died on May 11 1981 .


METASTATIC MALIGNANT MELANOMA

Q3. CONNECT


HIV AIDS WAS THE CAUSE OF DEATH

•FREDDIE MERCURY

• ISACC ASIMOV

•ARTHUR ASHE

•ROCK HUDSON

Q4.” Who killed Dr.Watson ? “ is an advertisement brought out by the Slovakian agency Soria & Grey .What are they trying to convey ?


PASSIVESMOKINGKILLS

Q5.• Thomas Latta was an English doctor and is considered to have introduced

this particular form of treatment in Medicine which is quite popular now .

• He introduced it during the Cholera epidemic in Britain in 1832 ,the results of his treatment were remarkably good & saved many lives .

• The results were published in the Lancet & the methodology spread ,however by then the epidemic was under control.

• There were inconsistent results also because of certain less understood mechanisms .

• Identify the treatment modality .


IV SALINE

Q6. (BONUS POINTS IF YOU ANSWER Z ALSO..)

• X :THE EXTRAORDINARY STORY OF A WONDER DRUG is a book written by Diarmuid Jeffreys.

• In the book ,Jeffreys has associated the drug with thye collapse of the Russian empire .

• The story goes like this…

• Alexei ,the son & heir of the last Czar , suffered from the disease Y .

• It is very likey that to ease the pain (that occurs in patients with Y) ,the then doctors prescribed him X , a popular drug then not knowing that X can actually complicate events in patients with Y .

• In desperation & fearing for the life of her son ,the Czarina Alexandra called upon Z ,who advised her to abandon modern treatments & surrender the boy to ‘faith healing’

• Without the drug X ,Alexei symptomatically improved ,and Z became close to the Royal family .

• This was seen as an increasingly corruptive influence in the febrile atmosphere at that time ,and it is regarded as a significant factor in turning Russsians against the Csar & in favour of revolution .

• Identify X ,Y & Z


X – ASPIRIN ; Y – HEMOPHILIA ; Z – GRIGORY RASPUTIN

Q7.

• X is an organomercury compound having antiseptic properties & is used as a preservative in vaccines ,immunoglobulin preparations ,antivenomsetc..

• The use of X as a preservative in vaccines is controversial , and in the European Union & in a few other countries ,it was phased out from routine childhood vaccines .

• The current consensus is that its use as a preservative is not known to have any severe adverse effects .


THIOMERSAL

Q8.

• This chemical , discovered in 1938 in Germany by Gerhard Scharder , Otto ambrose ,Gerhard Ritter & von der Linde acts by inhibiting the action of acetyl choline esterase enzyme present in the neuromuscular junction.

• It is one of the most toxic of the 4G series compounds .

• The United nations Chemical weapons Convention in 1993 banned its production & stockpiling .

• Name this chemical weapon which was used in Syria in April 2017


SARIN

Q9.

• X is an analgesic – a combination of hydrocodone & acetaminophen , manufacxtured by AbbVie.

• It is thought that the manufacturers named X as it was 6 times more potent than codeine (another analgesic)

• Identify X ,and explain the basis for its name .


VICODIN

Q10.• Thsese are some of the reasons which Prof.Jonadhan (University of Florida)

ascribes to this particular phenomenon

1.Wearing dark (navy,black ) & red apparel

2.Blood group O

3.Heavy breathers (the ones who exhale more)

4.People who sweat more (increased production of lactic acid ,uric acid ,ammonia & other compounds in the sweat)

5.The presence pf certain bacteria in the skin

6.Pregnancy

7.Alcoholics


THE REASON WHY SOME PEOPLE ARE MORE PRONE TO GET BITTEN BY MOSQUITOES

Q11.

• Zbigniew Religa was a popular Polish citizen – he became a member of the Polish senate in 1993 .

• He was a promising candidate in the Presidential elections in 2005 (he backed out of the election at the last moment ) and served as the Minister of Health from 2005 to 2007

• In 1987 , a picture featuring him , on the occasion of him achieving the very 1st in the countrt ,was chosen by the National Geographic as the best picture of the year .

• Identify the picture & the achievement


ANXIOUS EYES ;1st Heart Transplant surgery in Poland

Q12.

• The Australian Charles Rothauser created the world’s 1st

polypropylene based disposable X ,and it was so popular that he produced it in his factory for use in his country and for exporting to abroad .

• The previous versions of X were mostly made of glass.

• A modified ‘safer’ version was invented by a Keralite , Baby Manoj,and he won the Best Invention Award for the year 2011,given by theNational Development Reseach Corporation & also the Best Invention award of 2011 by the Geneva based World Intellectual Property Organisation.

• What is X ?


SYRINGE

AUDIENCE QUESTIONS

Q1.

• The Wisconsin Alumni Research Foundation is the independent non profit technology transfer organization serving the University of Wisconsin –Madison & Morgridge Institute for research .

• It provides significant research support ,granting tens of millions of dollars to the university each year & contributing to the University’s margin of excellence

• A drug ,which is on the WHO’s List of Essential Medicines ,is named after this organization .

• It first came to use in 1948 as a rat poison .

• In 1954 ,it was approved for use in humans .

• Name the drug


WARFARIN

Q2.

• This disease was named after a town/towns in the US state of Connecticut .

• The disease has an arthritis component usually affecting the knees .A cluster of cases originally thought to be Juvenile Rheumatoid arthritis was identified in 3 towns in Southeastern Connecticut in 1975 – this was investigated & found to be caused by spirochetes .

• THE DISEASE IS ?


LYME DISEASE

Q3.

• …………. ,also commonly called ‘cupping’ is a practice where blood is drawn out by vacuum from a small incision for therapeautic purposes

• It is a form of energy medicine because it has been claimed to unclog the meridians in the body ,and is viewed by some practioners as a cirethat can alleviate black magic & possession .

• The practice has Greek , Arab .Turkish & Persian origin & is mentioned by Hippocrates as well .

• The practice is ?


HIJAMA


ROUND 4

RULES

• 6 Questions

• Each question carry 10 points

• Pounce /Bounce Format ( +10/-10 for pounce)

Q1. Name this radiological sign & where do you find it ?

•A NATURAL LANDMARK IN JAPAN


MOUNT FUJI SIGN ;

TENSION PNEUMOCEPHALUS

Q2 . The chemical equation of which basic biochemical test ?


BENEDICT’S TEST

Q3.This sign is known as ? Where is it seen ?

Q4. What is this scoring system known as ? Its Importance ?


THE MALLAMPATI SCORE ; The ease of endotracheal intubation , The risk of OSAS

Q5.What is this hypothesis known as ?


MONROE KELLIE DOCTRINE

Q6. The ECG sign is known as ?

(Reverse Tick sign)


DIGITALIS EFFECT

SALVADOR ALI SIGN

TIE BREAKERS

Q1

• Rolla Neil Harger was a faculty in the department of biochemistry & pharmacology dof Indiana University School of Medicine .

• He invented X in 1931 .

• Robert F Borkenstein collaborated with Rolla in this invention .In 1936 ,Borkenstein joined in Indiana state Police & was later promoted to captain in charge of Police’s Forensic laboratory .

• In 1954 a modified version of X was invented by Borkenstein & it soon became popular

• In 1988 , he was inducted into The Safety & Health Hall of Fame International

• Identify X /modified version of X still in use .


BREATH ANALYSER

Q2

• A disease which affected many notable names in the literary world like Alexander Pope ,William Henley ;also served as the inspiration for Victor Hugo’s work The Huncback of Notre Dame

• The treatment for this condition is often referred to as The NiddlePath Regime

• What is the diseae I am talking ?


TUBERCULOSIS OF THE SPINE

Q3.

• Little ……… ………… was a daily American comic strip created by Harold Gray & syndicated by Tribune Media services

• The plot follows the wide ranging adventures of ……. , her dog Sandy & her benefactor Oliver Daddy Warbucks .

• The strip attracted adult readers with political commentary that targeted (among other things) organized labor ,the New Deal & communism .

• A characteristic cellular feature of a pathologic entity in the body is named after this character ,because of the cells ‘cleared out appearance’ similar to the eyes of ………… ………………..

• Name the character & the pathologic entity


ORPHAN ANNIE ; PAPILLARY CARCINOMA OF THYROID

Q4.• In 1952, a missionary in Borneo ( an Asian island) sent a sample of dirt to his

friend Dr. E. C. Kornfield, an organic chemist at Eli Lilly. An organism isolated from that sample (Streptomyces orientalis) produced a substance (“compound 05865”) that was active against most gram-positive organisms. Some anaerobic organisms, including clostridia, were also susceptible to compound 05865 , as was Neisseria gonorrhoeae .

• In vitro experiments were initiated to determine whether the activity of compound 05865 would be preserved despite attempts to induce resistance. After 20 serial passages of staphylococci from Eli Lilly laboratories, resistance to penicillin increased 100,000-fold, compared with only a 4–8-fold increase in resistance to compound 05865 .

• Before clinical trials were begun, the compound, dubbed “Mississippi mud”because of its brown color, needed to be purified.

• The purified entity was called X ( from the word ………….. Which means defeat ) ,and was made available for clinical trials

• Identify the drug & the root word (the blank)


VANCOMYCIN ; VANQUISH

Q5.

• The Chapter about Malaria in the 19th edition of “Harrison’s Principles of internal Medicine” begins with a famous saying by William Osler , a Canadian Physician who is regarded as “The Father of Modern Medicine”.

•Humnity has but 3 great enemies : ……….. , Famine & War ; Of these by far the greatest , by far the most terrible , is ……..

• FITB


ANSWER

• Fever

Mediquiz , a Medical trivia Quiz

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