Slide 1
Presented by :
1. Graha Ayu Praptiwi2. Junita Bri Hastuti3. Ruri Oktavianti
Uji Antiinflamasi Daun Jambu Mete (Anacardium occidentale L.)
Yang Ditimbulkan Pada Telapak Kaki Tikus Putih
JantanAntiinflammatory Activity of The Cashew Leaves On Hind Paw of
The Male White Rats
Background &PurposeP1Inflammation is a normal protective
response to tissue injury caused by physical trauma, damaging
chemicals or substances microbiologyNSAID have been used as
anti-inflammatory therapy but have side effect like
gastrointestinal distrubances so natural anti-inflammatory is
needed.
Powder microscopy of A.occidentale LinnCashew leaves (Anacardium
occidentale L.) has nature substances which have anti-inflammatory
characteristic like tanin, flavonoid, anakardiol acid , elagic
acid, fenol, kardol, methyl kardol, and salisilic acid. Determine
the effect of anti inflammation ethyl acetate extract of cashew
leaves (Anacardium occidentale L.) on edema in hind paw of Wistar
male rats compared with natrium diclofenacMethods of ResearchThis
research was a laboratory design using experimental method.
Thirty male white rats (2-3 month) of 100-200 gr were used in
this study and divided into 6 groups (5 rats each). P2
Male White RatsMale white rats were fasted for 18 hours and
still be drinkingGroup V(EAE III 1,8 g/kg BW)Group IV(EAE II 900
mg/kg BW)Group III(EAE I 450 mg/kg BW)Group II(Na diclofenac)Group
I
(aq.dest)Measuring first volume of the hind paw ratsThe
induction of inflammation was done by injecting 0,5% carrageenan
into the rats pawMeasuring hind paw volume every 30 minutes until
300 minutesThe data will be analyzed with statistically by ANOVA
test and DAI testConclusionGroup VI(EAE II + Na diclofenac)RESULT
OF THE RESEARCHBibliographiesSutrisna, E.M., Widyasari, Domas.,
Suprapto, Uji Efek Anti Inflamasi Ekstrak Etil Asetat Buah Semu
Jambu Mete ( Anacardium occidentale Linn) terhadap Edema pada
Telapak Kaki Tikus Putih (Rattus norvegicus) Jantan Galur Wistar
yang Diinduksi Karagenin, Universitas Muhammadiyah Surakarta.
Biomedika. 2010 ; II. 1
Nurain, Uji Efek Anti Inflamasi Ekstrak Buah Tomat (Solanum
lypopersicum L.) Pada Tikus Putih Jantan, Universitas Sebelas Maret
Jakarta. 2010.
Patil, MB,. Jalalpure, SS., Pramod, HJ., Manvi, FV., Anti
Inflammatory Activity of The Leaves of Anacardium occidentale Linn.
Mumbai, 2003, Vol. 65.
Pawar, S.P, Sathwane, P.N, Metkar, B.R, Pal, S.C, dkk, Anti
Inflammatory and Analgesic of Anacardium occidentale Linn Leaf
Extracts. PMC. 2000 ; 169-173.
Alur Proses Penelitian