taining the ocular surface of the eye: the role of eal epithelial stem cells in health and disease Mary Ann Stepp, Ph. D. Professor Department of Anatomy and Cell Biology and of Ophthalmology
Jan 03, 2016
Maintaining the ocular surface of the eye: the role of corneal epithelial stem cells in health and disease
Mary Ann Stepp, Ph. D.Professor
Department of Anatomy and Cell Biology and of Ophthalmology
How are the corneal epithelial stem cells maintainedthroughout our lifetime within their niche at the limbusdespite all the insults the ocular surface is forced to endure?
Some problems that can arise on the ocular surface…
After PRK RecurrentErosion
Corneal EpithelialStem Cell Deficiency
(CESCD)
Some problems that can arise on the ocular surface…
After PRK RecurrentErosion
Corneal EpithelialStem Cell Deficiency
(CESCD)
Development of mouse model for the study of these conditions
The cornea is optically wellsuited for microscopic analysis
QuickTime™ and aCinepak decompressor
are needed to see this picture.
4 integrin whole mount
The cornea is optically wellsuited for microscopic analysis
QuickTime™ and aCinepak decompressor
are needed to see this picture.
4 integrin whole mount
QuickTime™ and aCinepak decompressor
are needed to see this picture.
To get at the mechanism of these affects, we have a cell culture model we are using to study cell adhesion and migration.
QuickTime™ and aCinepak decompressor
are needed to see this picture.
To get at the mechanism of these affects, we have a cell culture model we are using to study cell adhesion and migration.
To get at the mechanism of these affects, we have a cell culture model we are using to study cell adhesion and migration.
Many important questions remain but we believe we have a model system that continues to give us new insight into the how
cell adhesion regulates the stem cell niche.
THANK YOU FOR YOUR ATTENTION!