LifePak® Nano Workshop North America Leadership Conference March 3, 2006 This material has been prepared by Pharmanex to be used in conjunction with general educational events and activities only. Alterations or modifications of this presentation without the express approval of Pharmanex is prohibited.
LifePak® Nano Workshop North America Leadership Conference March 3, 2006 This material has been prepared by Pharmanex to be used in conjunction with general.
Jan 03, 2016
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LifePak® Nano Workshop
North America
Leadership Conference
March 3, 2006
This material has been prepared by Pharmanex to be used in conjunction with general educational events and activities only. Alterations or modifications of this presentation without the express approval of Pharmanex is prohibited.
One unique technology teamed with Two proprietary products drive One exclusive sponsoring story
The Opportunity Simplified
Carsten R Smidt, Ph.D., FACN
Vice President,
Global Research & Development
Pharmanex
Huzhou Mfr. PlantShanghai R&D Center
Beijing Clinical Center Provo, Utah Headquarters & Pharmanex Research Institute
over 125 Scientists
Prof. Lester Packer
The Power of Nanotechnology
Nano-Switch
Nanotube Wires
What is Nanotechnology?1. Size: 1 -100 nanometers
– Most molecules are 1 to 100 nm in size
2. Function at the Molecular Level– Nanotechnology achieves new
functionalities by molecular rearrangements
Reasons for Limited Absorption
• Poor intestinal solubility• Requires fat for dissolution (e.g.,
Lipocarotenes)• Aggregation into large particles
– not easily digested and absorbed
The Nanotechnology DifferencePharmanex patent-pending & proprietary process
Small nano-nutrients are easily dispersed and absorbed
+
nano-carbohydrateshellCoenzyme Q10
nano-CoQ10
=
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
NanoCoQ10™
CoQ10 Absorption by Human Intestinal Cells
0.0
50.0
100.0
150.0
200.0
250.0
300.0
A B C D
pm
ol/m
g p
rote
in
NanoCoQ10
5-fold increase in absorption!
The Nanotechnology Difference
Intestinal Lumen Mucosa Cell(Intestinal Wall Cell)
Cel
l Mem
bra
ne
nano-CoQ10
Nano-Carbohydrate Shell
CoQ10
Nano-CoQ10
Carotenoids?
Nano-Carotenoids
lifepak® nano Study
15000
20000
25000
30000
35000
40000
0 2 4 6 8 10Time (weeks)
An
tio
xid
ant
Sco
re
Placebo
lifepak nano
?
60+ Antioxidants
Ongoing placebo-controlled clinical study
Nano-Carotenoids
Nano-CoQ10
Red WinePolyphenols
NewVitamin E
Highly Effective
Minerals
lifepak nano: 8 Formulas in 1
>
Complete, Balanced and Convenient
MultiVitaminMineral
Anti-oxidantFormula
GlucoseMetabolismFormula
ImmuneNutrientFormula
BoneFormula
Cardio-VascularFormula
AntiAging
Formula
The New Dimension!
• For All Adults (age 18-121)
• Proprietary Science• Broadest Health
Benefits
www.lifepaknano.com
Angela Mastaloudis, PhDAssociate Senior ScientistR&D, Pharmanex
• Ph.D. Exercise Physiology Oregon State University
• M.S. Nutrition Science Oregon State University
• Society for Free Radical Biology and Medicine – Young Investigator Award
• Lester Packer – Young Investigator Award
• Linus Pauling Institute– Graduate Fellowship
• New, broader-spectrum nano-carotenoid formula:– alpha-carotene– beta-carotene– lycopene– lutein– zeaxanthin (new): Eye health benefits*– astaxanthin (new): Inflammatory balance*
• as found in 5-10 fruits & vegetables per day
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
lifepak nano
Pharmanex Nanotechnology
• To increase intestinal uptake of poorly absorbed fat-soluble nutrients:– Carotenoids (lycopene, alpha+beta-carotenes,
zeaxanthin, astaxanthin)
– Coenzyme Q10
= Better Bioavailability*
= Increased Scanner Scores*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Purpose• How much more and how much faster
does lifepak nano increase scanner scores than a placebo?
ORORPLACEBOPLACEBO
Study Design ISupplementation• 52 Subjects were recruited and randomly assigned
to groups• Twice a day, with breakfast and with dinner,
subjects took:– lifepak nano
or– Placebo
• Study length: 18 weeks
Study Design II
BioPhotonic Scanner • Subjects were scanned a total of 15 times!
Diet• We encouraged to continue with their typical diet
for the entire study
Results• 42 out of 52 subjects completed the 18 week study
0
2,500
5,000
7,500
10,000
12,500
15,000
17,500
20,000
0 1 2 3 4 6 8 10 13 15 18
Weeks
Sca
nn
er
Sco
re In
cre
ase
(C
ou
nts
)
*
**
*
*
**
**
Scanner Scores Increase with lifepak nano
*p<0.05 between groups
45% Increase!
41% Increase!
37% Increase!
30% Increase!
19% Increase!
Scanner Scores Increase with lifepak nano
*p<0.05 compared to wk 0 #p<0.05 compared to placebo
#, *#, *
#, *
#, *#, *
#, *#, *#, *#, *
10,000
15,000
20,000
25,000
30,000
35,000
40,000
45,000
0 1 2 3 4 6 8 10 13 15 18
Weeks
Sca
nn
er
Sco
re (
Co
un
ts)
LifePak Nano Placebo
NSE NSE GlobalGlobal
ConventionConvention
Scanner Scores Increase with lifepak nano
*p<0.05 compared to wk 0 #p<0.05 compared to placebo
#, *#, *
#, *
#, *#, *
#, *#, *#, *#, *
10,000
15,000
20,000
25,000
30,000
35,000
40,000
45,000
0 1 2 3 4 6 8 10 13 15 18
Weeks
Sca
nn
er
Sco
re (
Co
un
ts)
LifePak Nano Placebo
Summary• Lifepak nano increased scanner scores as
fast as two weeks
• Scanner scores increased in all 20 subjects taking lifepak nano
• Lifepak nano increased scanner scores 18,000 units more than placebo in 18 weeks
• Even after 18 weeks scanner scores were still increasing in the lifepak nano group
Better Bioavailability*
Faster and Higher Increases in Scanner Scores*
=
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The Power of Nanotechnology
Visit our PRODUCT SHOWCASE!
Key Business Takeaways• Nanotechnology increases absorption of poorly absorbed nutrients*
• First in industry to apply nanotechnology to a multivitamin supplement*
• Proprietary and patent-pending
• Guaranteed to increase SCS* • Clinically proven ~ 18,000 increase
• Do You NANO?
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
www.lifepaknano.com
More InformationPresentations
www.pharmanexusa.com
Leadership Conference link
My Office Marketing Tools
Product Resources
www.pharmanexusa.com
www.pharmanexscanner.com
www.lifepaknano.com
Product Support
E-Mail: [email protected]
Phone: 1-800-487-1000
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