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Lecture 11Based on Chapter 17 -Regulation of Gene Expression in Bacteria and Bacteriophages
Copyright © 2010 Pearson Education Inc.
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2 – The lac Operon of E. coli
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3 – Lactose as a carbon Source for E.coli
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4 - Experimental Evidence for the Regulation of lac Genes
The experiments of Jacob and Monod produced an understanding of arrangement and control of the lac genes.
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5 – Mutations in the Protein-Coding Genes
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6 – Mutations affecting the Regulation of Gene Expression
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7 – Operator Mutations
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8 – lacI Gene Regulatory Mutations
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9 – Jacob & Monod’s Operon Model for the Regulation of lac Genes
Figure 17.5
Figure 17.6
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10 – Induction of lac by Allolactose (lactose)
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11a – Effect of lac Oc Mutations (merodiploid)
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11b – Effect of lac Oc Mutations (merodiploid)
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12a – Effect of lacI- Mutations
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12b – Effect of lacI- Mutations
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12c – Effect of lacI- Mutations
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13 – Additional lacI Mutations
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14 – Positive control of the lac Operon
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15 – Molecular Details of lac Operon Regulation
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16 - The trp Operon of E. coli
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17 – Molecular Model for Attenuation
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18 – Molecular Model for Attenuation
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19 – Genetic Evidence for Attenuation
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20 – Attenuation at Other Operons
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21 – The ara Operon of E. coli: Positive and Negative Control
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22 – Regulation of Gene Expression in Phage Lambda
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23 – Early Transcription Events
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24 – The Lysogenic Pathway
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25 – The Lytic Pathway