The suite is equipped with a high pressure homogenizer (Aves- tin) which will allow the disruption of dissimilar samples with a minimum maintenance and a low cost. The equipment has a built-in compressed air supply (100 psi) which will allow to pro- cess different samples: liposomes (70 psi), E. coli (70 psi) and Pichia (100 psi). The installed cooler of the equipment, con- nected to tap water, keeps the temperature low during sample disruptions. The suite is also equipped with Dyno-Mill cell dis- ruptor to process yeast samples. The equipment is fitted with a circulating bath which allows the disintegration of samples at low temperatures. For small volume of samples, BeatBeater is also available. The suite is equipped with one large-scale fermentation system (70-L stainless steel bioreactor). A steam generator is installed for one-step in-suite sterilization. It has an Applikon bio-controller (Model ADI 1010) and Pilot system (ADI 1075) with three pneumatic pumps (acid, base, and antifoam), stirrer controller, and rotameters, which provide user-friendly setup and automated control/recording of temperature, pH, dissolved oxygen (dO2) during the fermentation process. One computer is installed with BioXpert software for large-scale fermentation. The suite is equipped with six small-scale fermentation systems (three with 3-L bioreactors and three with 7-L bioreactors) available for Escherichia, Streptomyces, Rhodobacter, Salmonella, Bacillus and others. Each fermentation system has an Applikon bio-controller (ADI 1030), stirrer controller (ADI 1032), three rotameters (air, O2, N2), and three pneumatic pumps (acid, base, antifoam/label), which allow automated control/ recording of temperature, pH, and dissolved oxygen (dO2) during the fermentation process. One computer is installed with BioXpert software for bacterial fermentation. Bacterial Fermentation System (3-L or 7-L) The suite is equipped with a CEPA high speed centrifuge to harvest large volume of cells and media. It allows the collection of 50 liters of media within 45 minutes. The sample port of the 70-L fermenter can be directly connected to the high speed centrifuge to allow the harvest of samples after the fermentation process. CEPA Z41 High Speed Centrifuge Eukaryatic Fermentation System (3-L or 7-L) Cell Disruption Equipment Among the six small-scale fermentation systems, three of them are also equipped with individual methanol (MeOH) detectors and sensors from Raven Biotech Inc. and pumps for automatic control/recording of MeOH level in the media during Pichia fermentation. Large-scale Fermentation System (70-L) One computer is installed with BioXpert software for Pichia fermentation. The suite also has one separate bioreactor (3-L) with marine type impeller and sparger suitable for animal cell culture. The suite is equipped with one DASGIP OD4 module and three DASGIP Optical Density Probes, 12 mm diameter, 225 mm inser- tion length w/ 5 mm light path. Easy access software (DASGIP) is installed in all computer system for recording. DASGIP OD4 module Labnet incubator shaker for Pichia culture The suite is equipped with one Labnet Incubator Shaker (I5311-DS) for plate incubation and small scale (50-ml flask or 50-ml falcon tubes) culture exclusively for Pichia cells.