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 An Alternative Approach for Quantitative Bioanalysis using Diluted Blood to Prole Oral Exposure of Small Molecule Anticancer Drugs in Mice LOWIS YANMANIAR I22112015 STEFANIE AUDINA I22112036
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Jurnal Bioanalisis 015-036

Jan 18, 2016

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Page 1: Jurnal Bioanalisis 015-036

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An Alternative Approach for

Quantitative Bioanalysis usingDiluted Blood to Prole OralExposure of Small Molecule

Anticancer Drugs in Mice

LOWIS YANMANIAR I22112015

STEFANIE AUDINA I22112036

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• A quantitative biana!"ti#a! $et%&'( )%a($a#*ineti# +tu&ie+ u+in,&i!ute& -%!e b!& '($ +e(ia!!" b!e&$i#e -a+ &eve!)e&.

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•  T%i+ $et%& )(vi&e+ +i,ni9#ant )(#e++i$)(ve$ent b" en%an#in, e#ien#" '(+a$)!e #!!e#tin an& )(#e++in, an&

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• Met&e ini $e$be(i*an )e(bai*an )(+e+ "an,+i,ni9*an &en,an $enin,*at*an

• e9+ien+i untu* )en,u$)u!an +a$)e! &an

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$enunGu**an )ene(a)an $en,,una*an +a$)e!&a(a% $i*( &ien#e(*an untu* *e#i! biana!"+i+*uantitati' $!e*u! untu* $en&u*un, +tu&i ti*u+&a!a$ )ene$uan bat