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Insulin s.c. depot: Heaps Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208
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Insulin s.c. depot: Heaps1).pdf · Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208 . y Size Small molecule Drug Medium sized Molecule IgG Antibody

Jun 05, 2020

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Page 1: Insulin s.c. depot: Heaps1).pdf · Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208 . y Size Small molecule Drug Medium sized Molecule IgG Antibody

Insulin s.c. depot: Heaps

Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208

Page 2: Insulin s.c. depot: Heaps1).pdf · Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208 . y Size Small molecule Drug Medium sized Molecule IgG Antibody

Com

plex

ity

Size

Small molecule Drug Medium sized Molecule IgG Antibody 300-600 Da 1K – 3K Da 25,000 Da

Size and complexity : from small molecule to Protein

Self assembly Re-build take to the garage Ask for new robotics ! (3 computers,67 sensors) Built in instability

Page 3: Insulin s.c. depot: Heaps1).pdf · Søeborg et al., European Journal of Pharmaceutical Sciences 46 (2012) 198–208 . y Size Small molecule Drug Medium sized Molecule IgG Antibody

The Clyde Arc: “The Squinty Bridge”