INFECTION AND IMMUNITY - ASM Journals

INFECTION AND IMMUNITYVOLUME 61 * DECEMBER 1993 * NUMBER 12

Vincent A. Fischetti, Editor in Chief(1994)

Rockefeller UniversityNew York N.Y.

Barry I. Eisenstein, Editor (1994)Lilly Research LaboratoriesIndianapolis, Ind.

Stanley Falkow, Minireview Editor (1995)Stanford University School ofMedicineStanford, Calif.

Dexter H. Howard, Editor (1996)University of CaliforniaLos Angeles, Calif.John M. Mansfield, Editor (1998)University of WisconsinMadison, Wis.Roderick E. McCallum, Editor (1998)Te-xas A&M University HealthScience Center

College Station, Tex.Jerry R. McGhee, Editor (1994)University ofAlabamaBirmingham, Ala.

Carol A. Nacy, Editor (1995)EntreMed, Inc.Rockville, Md.

Alison O'Brien, Editor (1996)Uniformed Services University of theHealth Sciences

Bethesda, Md.

Philippe J. Sansonetti, Editor (1997)Institut PasteurParis, France

Soman N. Abraham (1994)Julia W. Albright (1995)Glen Armstrong (1995)Sandra K. Armstrong (1993)Joseph T. Barbieri (1995)Alan G. Barbour (1995)Scott Barnum (1995)Joel B. Baseman (1994)Robert E. Baughn (1993)Patrick Bavoil (1993)Blaine L. Beaman (1994)Jorge L. Benach (1995)D. Kay Blanchard (1995)Martin J. Blaser (1995)Arnold S. Bleiweis (1993)W. Chaunce Bogard (1995)Gregory A. Bohach (1993)Patrick Brennan (1994)David E. Briles (1994)Robert R. Brubaker (1993)Drusilla L. Burns (1994)Gerald Byrne (1994)Richard A. Calderone (1993)Stephen Calderwood (1994)Harlan Caldwell (1993)Priscilla A. Campbell (1993)Janne G. Cannon (1993)Gail H. Cassell (1993)John Chan (1994)Bruce Chassy (1993)Ambrose Cheung (1993)Nicholas P. Cianciotto (1993)Witold Cieplak (1994)John 0. Cisar (1994)Josephine Clark-Curtiss (1993)P. Patrick Cleary (1993)Steven Clegg (1993)John D. Clements (1995)Don B. Clewell (1993)Myron S. Cohen (1993)Paul S. Cohen (1993)R. John Collier (1994)Frank M. Collins (1995)Guy Cornelis (1993)Rebecca Cox (1993)Jorge H. Crosa (1994)Jim E. Cutler (1993)

Barbara H. Iglewski, Chairman,

EDITORIAL BOARDCharles J. Czuprynski (1995)George S. Deepe, Jr. (1995)Judith E. Domer (1995)Gordon Dougan (1994)Lawrence A. Dreyfus (1993)Roman Dziarski (1993)Robert A. Eisenberg (1993)Toby K. Eisenstein (1993)John H. Eldridge (1995)Charles 0. Elson (1995)N. Cary Engleberg (1995)Joseph C. Fantone IH (1993)Joseph J. Ferretti (1995)Dara W. Frank (1993)Rolf G. Freter (1993)Ronald J. Gibbons (1994)Janet R. Gilsdorf (1993)Mae Go (1993)William E. Goldman (1995)Emil Gotschlich (1994)Patricia Guerry-Kopecko (1993)Paul Gulig (1993)Thomas L. Hale (1993)Jane L. Halpern (1993)Shigeyuki Hamada (1993)Eric J. Hansen (1995)David L. Hasty (1994)Richard Hector (1995)Fred Heffron (1993)Erik Hewlett (1993)James B. Hicks (1994)Susan Hollingshead (1995)Jan Holmgren (1994)Anne Morris Hooke (1995)Ralph R. Isberg (1993)Graham Jackson (1995)Matt Jackson (1995)William R. Jacobs, Jr. (1993)James B. Kaper (1994)Stefan H. E. Kaufmann (1995)Paul M. Kaye (1994)Mogens Kilian (1993)Theo N. Kirkland (1995)Hiroshi Kiyono (1995)Dennis J. Kopecko (1995)Malak Kotb (1994)Thomas R. Kozel (1994)

Publications Board

Arnold Kreger (1995)Howard K. Kuramitsu (1994)David Leiby (1995)Myron Levine (1994)Stephen Lory (1993)Carl F. Mam (1993)Anthony Maurelli (1993)Bruce McClane (1995)John Mekalanos (1995)Eleanor S. Metcalf (1995)Suzanne M. Michalek (1995)Michael L. Misfeldt (1994)Harry Mobley (1995)Robert L. Modlin (1995)Robert N. Moore (1995)Steve L. Moseley (1993)Richard Moxon (1993)Antony J. Mukkada (1993)Martha H. Mulks (1995)Robert S. Munford (1992)Robert S. Munson (1995)Juneann W. Murphy (1993)Thalia I. Nicas (1995)Michael V. Norgard (1995)Robert North (1995)Dennis E. Ohman (1995)Andrew B. Onderdonk (1993)Paul Orndorff (1993)Michael J. Parmely (1995)Jeffrey Parsonnet (1995)Shelley M. Payne (1994)Kenneth Peterson (1993)William A. Petri, Jr. (1993)Gerald B. Pier (1995)Daniel A. Portnoy (1995)Richard A. Proctor (1993)Justin D. Radolf (1993)Reuben Ramphal (1994)Jonathan I. Ravdin (1995)Richard F. Rest (1993)Judith C. Rhodes (1995)Donald Robertson (1993)Sara W. Rothman (1993)Craig E. Rubens (1994)Michael W. Russell (1994)Roy R. B. Russell (1995)Catharine Saelinger (1993)

Linda M. Illig, Director, Joumals

James Samuel (1995)Stewart Scherer (1994)Patrick Schlievert (1993)June R. Scott (1993)Penelope G. Shackelford (1995)Alan Sher (1995)Thomas M. Shinnick (1994)Richard P. Silver (1995)Richard Silverstein (1995)Jerry Simecka (1994)Emil Skamene (1994)Jack D. Sobel (1993)P. Frederick Sparling (1993)Walter E. Stamm (1993)George Stewart (1993)Susan C. Straley (1995)Barnet M. Sultzer (1994)Catharina Svanborg (1993)John L. Swanson (1993)Yosifumi Takeda (1994)Martin A. Taubman (1993)Diane W. Taylor (1993)John Thompson (1993)Michael R. Thompson (1993)Trevor J. Trust (1994)Elaine Tuomanen (1993)Rodney K. Tweten (1993)Ivo van de Rin (1993)Thomas E. Van Dyke (1995)Jan D. A. van Embden (1994)Michael L. Vasil (1993)Peter A. Ward (1994)Alison Weiss (1995)Rodney Welch (1993)Tracy D. Wilkins (1993)Dwight Williams (1993)Peter H. Williams (1993)Mark E. Wilson (1994)Herbert H. Winkler (1995)Marcia K. Wolf (1993)Patricia L. Worsham (1993)Priscilla B. Wyrick (1993)Douglas B. Young (1994)Lowell Young (1994)H. Kirk Zeigler (1995)

Jack Kenney, Production Editor

Infection and Immunity, a publication of the American Society for Microbiology (ASM), 1325 Massachusetts Ave., N.W., Washington, DC 20005-4171,is devoted to the advancement and dissemination of fundamental knowledge concerning: (i) infections caused by pathogenic bacteria, fungi, and parasites;(ii) ecology, epidemiology, and evolution of pathogenic microbes; (iii) mechanisms of pathogenicity and virulence factors such as toxins and microbialsurface structures; (iv) nonspecific factors in host resistance and susceptibility to infection; (v) immunology of microbial infection; and (vi) developmentand evaluation of vaccines against pathogens. Instructions to authors are published in the January issue each year; reprints are available from the editorsand the Journals Division. Infection and Immunity is published monthly, one volume per year. The nonmember print subscription prices are $350 (U.S.)(Canadians add 7% GST) and $410 (other countries) per year; single copies are $40 (Canadians add 7% GST). The member print subscription prices are$51 (U.S.) (Canadians add 7% GSTj) and $89 (other countries); single copies are $10 (Canadians add 7% GST). For prices of CD-ROM versions, contactthe Subscriptions Unit, ASM. Correspondence relating to subscriptions, defective copies, missing issues, and availability ofback issues should be directedto the Subscriptions Unit, ASM; correspondence relating to reprint orders should be directed to the Reprint Order Unit, ASM; and correspondencerelating to disposition of submitted manuscripts, proofs, and general editorial matters should be directed to the Journals Division, American Society forMicrobiology, 1325 Massachusetts Ave., N.W., Washington, DC 20005-4171. Phone: (202) 737-3600.Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months after publication of the issues;

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Author IndexAbbink, J. J., 5035Abe, Norio, 5309Apter, Felice M., 5271, 5279Arata, Satoru, 5056Arvieux, Josiane, 5134

Bachelet, Maria, 5286Bakhiet, Moiz, 5129Barbet, Anthony F., 5245Barrett, R., 5164Barrow, William W., 5286Barthold, Stephen W., 4955Baskin, Gary, 5214Baumstark, Manfred W., 5140Bavari, Sina, 5333Berche, Patrick, 5134Berg, Aloys, 5140Betley, Marsha J., 5421Bhakdi, Sucharit, 4972Bhardwaj, N., 5326Binsztein, Norma, 5190Blake, D. C., Jr., 5384Blaser, Martin J., 5008Boom, W. Henry, 5410Boquet, Patrice, 5147Borst, Deborah W., 5421Britigan, Bradley E., 5049Burrows, Lori L., 5001Butterworth, Anthony E.,4984

Cao, Ping, 5008Carbone, F. R., 5374Chang, A., 5035Chang, Swei-Ju, 5345Chen, Wangxue, 5406Chiu, Chung-Yin, 5345Ciolli, L., 5225Coleman, Lisa A., 5115Colomb, Maurice G., 5134Cornillet, P., 4980Cover, Timothy L., 5008Creasey, A. A., 5035Croize, Jacques, 5134

Dao, My Lien, 5021Daugherty, Shannon, 5078Davis, Terry L., 5286de Boer, J. P., 5035DeBuron-Connors, Isaure,

4962de Sousa, Joao Paulo

Carvalho, 5286Desperrier, Jean-Michel, 5106Dias, Feliciano, 5097Dickinson, Douglas P., 5181Dillon, Harrison F., 5426Doebbeling, Bradley N., 5049Dong, Zhao Ming, 5067Dunn, Pamela L., 5302Dunne, David W., 4984

Eckmann, Lars, 5231Eerenberg, A. J. M., 5035Engel, Andreas, 5413Engstrom, Suzanne M., 5115

Fang, Ferric, 5231Fick, Robert B., Jr., 5049Fierer, Joshua, 5231Finkelstein, Richard A., 5271Finlay, B. Brett, 5231Flegel, Willy A., 5140

Friedman, Herman, 5056Fujii, Nobuhiro, 5309Fukada, Masako, 5044Fulford, Anthony J. C., 4984

Garcia, Marie Isabelle, 5106Gebhart, C. J., 5237Gerstenecker, Bernhard, 5315Gibert, Maryse, 5147Gigliotti, Francis, 5406Gillin, Frances D., 5394Goldberg, Marcia B., 4941Gounon, Pierre, 5106Graham, Brett, 5426Granfors, Kaisa, 5261Greco, F., 5225Gross, Mitchell, 5062Guenounou, M., 4980Guinand, Micheline, 5417Guiney, Donald, 5231

Hack, C. E., 5035Hanazawa, Shigemasa, 5219Hansen, Eric J., 5157Harmsen, Allen G., 5406Havell, Edward A., 5174Hayek, Michael B., 5049Hazlett, L. D., 5164Hetherington, Seth V., 5157Hetsko, Michael L., 5394Hibi, Eiko, 5181Hill, Joseph O., 5302Hoffman, Stephen L., 5062Hughes, Carrie A. Norton,

5115Hultenby, Kjell, 5351Husmann, Linda K., 5426

Igarashi, Hideo, 5252Iwanaga, Masaaki, 5398

Jalkanen, Sirpa, 5261Jelonek, Marie T., 5345Jiang, Guo-Zhi, 5044Johnson, Lawrence L., 5174Johnson, Russell C., 5115Jonas, Daniel, 4972Jones, G. F., 5237

Kaack, M. Bernice, 5214Kamau, Timothy, 4984Kato, Hiroshi, 5181Kawabata, Yoshihiro, 5252Kawai, Makoto, 5044Kawata, Yasuhiro, 5219Kazura, James W., 5410Kern, Peter, 5413Kern, Winfried V., 5413Kersten, Astrid, 5315Kim, Mary F., 5123Kimani, Gachuhi, 4984Kimsey, Paul B., 5205Kist, Manfred, 5315Kitano, Shigeo, 5219Klein, Thomas W., 5056Kodama, Hiroshi, 5392Kodner, Carrie B., 5115Kotani, Shozo, 5252Krakauer, Teresa, 5333Kristensson, Krister, 5129Krogfelt, Karen A., 5029Kumada, Hidefumi, 5219Kumashiro, Ryunosuke, 5388

Kunz, Leoni, 4972Kusters, Johannes G., 5013

Labigne, Agnes, 5106Landen, Ritva, 4947Le Bouguenec, Chantal, 5106Le Bras, Jacques, 5198Lee, Chi-Jen, 5401Lefebre, C., 4980Lencer, Wayne I., 5271Lepers, Jean Paul, 5198Lind, Christopher D., 5008Lindberg, Alf A., 5351Lindsay, Dwight D., 5388Lo, Reggie Y. C., 5001Lovgren, Ann, 4947Low, Martin G., 4947, 5078Lundin, Knut E. A., 5294

Mack, Julie A., 5279Mak, Tak, 5129Malik, Anita, 5062Martin, Edith, 4972Masinick, S., 5164Masuda, Tamuro, 5219Matsiota-Bernard, P., 4980Matsushita, Kenji, 5252Mawhorter, Steven D., 5410Mekalanos, John J., 5271,5279

Meng, Tze-Chiang, 5394Michel, Georges, 5417Michetti, Pierre, 5279Minnick, Michael F., 4962Mirza, A., 5326Mitchen, Tonya K., 5205Mohamadzadeh, Mansour,4972

Molin, S0ren, 5029Moriishi, Kohji, 5309Mulders-Kremers, GeraldinaA. W. M., 5013

Muller-Klieser, Wolfgang,4972

Murphy, Juneann W., 5067Murtaugh, M. P., 5237Mustafa, Abu S., 5294

Nahm, Moon H., 5345Naiki, Masaharu, 5309Nakasone, Noboru, 5398Neutra, Marian R., 5271, 5279Newton, Catherine, 5056Northoff, Hinnak, 5140

Oberle, Suzan M., 5245Oftung, Fredrik, 5294Oguma, Keiji, 5309Ohishi, Iwao, 5392Ohkuni, Hisashi, 5252Okithu, Mithuhisa, 5219Olah-Winfield, Elizabeth, 5001Oliveira, Sergio C., 5339Olsson, Tomas, 5129Orn, Anders, 5129Ouin, Valerie, 5106Ouma, John H., 4984

Padula, Steven J., 5097Palmer, Guy H., 5245Pancholi, P., 5326Park, Moon K., 5345Patrick, Christian C., 5157

Pearce, Edward J., 5381Pearlman, Eric, 5410Perelle, Sylvie, 5147Perez-Casal, Jose F., 5426Peyron, Francois, 5198Pfeifer, Cheryl, 5231Popoff, Michel R., 5147Posteraro, P., 5225Poulsen, Lars Kongsbak, 5029Prummer, Otto, 5413

Qian, Hong, 5021

Rabarison, Patrick, 5198Rabodonirina, Meja, 5198Rakotomalala, Charles, 5198Rastogi, Nalin, 5286Razanamparany, Marcel, 5198Ringwald, Pascal, 5198Roberts, James A., 5214Roberts, Morven, 4984Roem, D., 5035Rogers, Howard W., 5090Rose, R., 5237Rosol, K., 5164Rossi, A., 5225Rottenberg, Martin E., 5129Roux, Jean, 5198Russell, R. G., 5384Rutault, Karine, 5417Ryan, Raymond W., 5097

Sadosky, Alesia B., 5361Saito, Masayuki, 5309Sampieri, Alicia, 5097Sansonetti, Philippe J., 4941Schauf, V., 5326Scherer, David C., 4962Schieffer, S., 5413Schiltz, Emile, 5315Scott, June R., 5426Sedqui, M., 4980Shnyra, Alexander, 5351Shuman, Howard A., 5361Spagnolo, N., 5225Spiegelhalder, Christiane,5315

Splitter, Gary A., 5339Steinman, R. M., 5326Stiles, Bradley G., 5333Strugnell, R. A., 5374Sturrock, Robert F., 4984Svennerholm, Ann-Mari, 5190Svenson, Stefan B., 5214Syuto, Bunei, 5309Szczepanski, Andrew, 5097

Tai, Stanley S., 5401Takada, Haruhiko, 5252Takahashi, Kazuko, 5044Takahashi, Yukihiro, 5181Takasawa, Toshihide, 5181Takeshita, Akira, 5219Tamura, Masato, 5252Tanaka, Shoji, 5219Tart, Rebecca Creech, 4994Taylor, F. B., Jr., 5035Teti, A., 5225Tham, Kyi T., 5008Theiss, Patty M., 5123Theodos, Cynthia M., 5205Titus, Richard G., 5205Todome, Yuko, 5252

i

ii AUTHOR INDEX INFECT. IMMUN.

Toivanen, Paavo, 5261Turco, Salvatore J., 5205Turner, S. J., 5374

Uchiyama, Takehiko, 5252Ulrich, Robert G., 5333Ulrich, Terry, 5062Umemoto, Toshio, 5219Unanue, Emil R., 5090

Vacheron, Marie-Jeanne, 5417

van de Rijn, I., 4994VanderVegt, F. Pierre, 5174van der Zeijst, BernardA. M., 5013

van Doornik, Claudia E. M.,5013

Vella, Anthony T., 5381Viboud, Gloria Ines, 5190

Walev, Iwan, 4972Ward, G. E., 5237

Ward, Joel I., 5345Weinstock, Christof, 5140Wiater, Lawrence A.,

5361Wigzell, Hans, 5129Willett, Norman P., 5388Winner, L. S., III, 5279Winter, Ruth E., 5401Wise, Kim S., 5123Wright, Esther L., 5286Wuorela, Maarit, 5261

Yamamoto, Masashi, 5388Yamamoto, Nobuto, 5388Yamamoto, Yoshio, 5219Yamashiro, Tetsu, 5398Yokochi, Takashi, 5044Yoshimura, Fuminobu, 5181

Zhang, Min-Ying, 4947Zhang, Yue-Hua, 5044Zhu, Yingxun, 5339

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AUTHOR INDEX

VOLUME 61

Abachin, Eric, 1576Abbink, J. J., 5035Abdelnour, A., 3879Abe, Norio, 5309Abebe, E., 350Abrahamsen, Tore G., 1779Abrams, John S., 197, 3482,

4038Abrams, V. L., 2520Abu Kwaik, Yousef, 1320Acheson, David W. K., 1098Actis, Luis A., 3228Adams, L. B., 4173Adriani, Daniela, 1500Aebischer, Toni, 220, 3459Afare, E. A., 268Afonso, Luis C. C., 2952Agace, William, 602Agerberth, Birgitta, 2978Ahlers, Jeffrey, 1958Ahrens, Ralph, 2505Aiura, Koichi, 3342Aizawa, Yuzuru, 2096Ak, Mucide, 2493Akaike, Takaaki, 1980, 3552Akashi, Akira, 1700Akashi, Tomohiro, 3164Akhiani, A. A., 4919Akins, Damfin R., 1202Ala'Aldeen, Dlawer A. A.,

751Alaei, S., 1395Alberti, Sebastian, 852Albizu, Ifiaki, 4857Alexander, Janet E., 2245Aley, Stephen B., 520Alfa, Michelle J., 1735Alfano, M., 1453Alfarone, Giovanna, 1272Ali-Salaam, Pia, 2899Allan, Richard J., 4772Allaoui, Abdelmounaaim, 1707Allen, Stephen J., 103Allendoerfer, R., 714Ally, B., 4085Alonso-Vega, Cristina, 4280Alouf, J. E., 1055Alpers, Michael P., 988, 2425Alvarez-Dominguez, Carmen,

3664Amano, Ken-Ichi, 4350Amaro, Carmen, 1611Ameglio, Franco, 439Amorena, Beatriz, 4857Amsbaugh, Diana F., 1447Anaissie, Elias, 1268Andersen, Grace B., 2122Andersen, Peter, 844Andersen, Roxanna Neikirk,

981Anderson, Burt E., 3536Anderson, Carol, 565Anderson, Daniel C., 2220Anderson, Julia, 1823Anderson, Karen F., 2220Andersson, Jan, 602Andersson, Ulf, 602Ando, Masayuki, 1980, 3552Andrade, Sylvia, 4937Andrew, P. W., 2245Andrews, Ryan P., 4703

Andujar, Mauricio, 2732Angus, R. Dale, 1722Ansher, Sherry, 4240Antoniades, Harry N., 4622Apicella, Michael A., 3360Apter, Felice M., 5271, 5279Aragon, Adam S., 4232Arai, Sumio, 1700Arakawa, Masaaki, 1334Arakawa, Yoshichika, 3164Arala-Chaves, Mario, 1881Arata, Satoru, 5056Araujo, Fausto G., 2639Araujo-Jorge, Tania, 4925Araya, Jorge Enrique, 3636Arditi, Moshe, 3149Arko, R. J., 1232Armstrong, Jason W., 4013Arnold, R., 2545Arnon, Ruth, 2390Arvidson, S., 3879Arvieux, Josiane, 5134Asano, Misako, 2786, 2872Asherson, Geoffrey L., 2122Ashkenazi, Shai, 3678Ashley, Lauren S., 1772Astagneau, P., 4498Ataoglu, Haluk, 3313Athamna, Abed, 4208Atkinson, H. Max, 371Augustine, Nancy H., 2334Auregan, Guy, 742Ausiello, Clara M., 4105Autenrieth, Ingo B., 2585Axt, Roland, 3143Aydintug, M. Kemal, 2995,

3047Ayers, Gregory D., 619Azen, Edwin, 4434Azghani, Ali O., 2681Azuma, Ichiro, 329

Babakhani, Farah K., 2723,3466

Baca, Oswald G., 4232, 4485Bachelet, Maria, 5286Bachmann, S., 4645Baek, Kwang Hyeon, 1091Bagasra, Omar, 3559Bahrani, Farah K., 884Baker, Carol J., 1415, 2866Baker-Zander, Sharon A., 781Bakhiet, Moiz, 5129Bakker, M. H., 303Baldacini, Olivier, 1082Baldwin, Cynthia L., 124Baldwin, Tom J., 760Balish, Edward, 3530Ball, Donald W., 2912Bandyopadhyay, Santu, 3565Baranton, Guy, 2717Barberan, Montserrat, 4857Barbet, Anthony F., 5245Barbieri, Clara L., 2131Barbieri, Joseph T., 307Barbour, Alan G., 81, 2192,

3590Barchfeld, Gail L., 2041Barclay, G. Robin, 3863Barile, M. F., 1523Barington, Torben, 432

Barker, Andrew, 3032Barker, J., 3503Barker, Steven A., 1Barluzzi, Roberta, 3476Barnard, Amanda, 399, 3190Barnes, Peter F., 197, 3482Baron, S. S., 182Barr, Philip J., 2041, 2048,

3403Barras, Catherine, 378Barrett, R., 5164Barrow, William W., 5286Barthold, Stephen W., 1586,

1814, 2104, 2553, 4493,4696, 4955

Bartlett, Marilyn S., 1315Barton, Beverly E., 1496Barton, Peter A., 1474Barturen, Begonia, 4842Barzu, Simona, 3825Baselga, Rafael, 4857Baseman, J. B., 816Baskin, Gary, 2289, 5214Basu, Debasis, 3565Bates, Janice, 4382Bathurst, Ian C., 2041, 2048Batsford, Stephen, 2498Bauer, Nancy L., 1315Baumgartner, Jean-Daniel, 378Baumstark, Manfred W., 5140Bavari, Sina, 5333Beaman, Blaine L., 274, 343,

955Beaman, Lovelle, 343Beaman, Miles H., 4038Bean, Andrew G. D., 4937Beaudoin, Richard L., 2493Beck, Deborah S., 1814, 4493Becker, M., 4716Bedi, Gurrinder S., 2369Beharka, Alison A., 4013Behling, Cynthia A., 2296Beighton, David, 295Beining, Paul, 1722Bekelie, Siraj, 3642Belanger, Myriam, 4785Belay, T., 2879Belosevic, Miodrag, 1553Benabdelmoumene, Salim,

1082Bender, D. E., 4645Bendtzen, Klaus, 1069Benedetto, Nunzia, 155Benedi, Vincente J., 852Bennett, Beth, 2296Bennett, Michael, 4615Bennett, Stephen, 103Beraud, M., 1432Berche, Patrick, 1576, 5134Berg, Aloys, 5140Berger, Hans-Peter, 4915Bergman, Cheryl, 3351Bergman, Thomas, 71Berish, Sally A., 4599Beristain, Suzanne, 3282Berk, Richard S., 2713Bermudez, Luiz E., 3093,4126

Bernabeu, Carmelo, 4225Bernardini, Maria L., 3625Bernhard, Wolfgang, 1687

Bertram, G., 4263Berzofsky, Jay A., 1958Beschin, Alain, 439Besser, Thomas E., 2558Bessieres, M. H., 1432Betley, Marsha J., 356, 1581,

2059, 3175, 5421Betsou, Fotini, 3583Betts, Michael, 1722Beutin, Lothar, 2138Beynen, A. C., 303Bhakdi, Sucharit, 1715, 4972Bharadwaj, Dwaipayan, 3565Bhardwaj, N., 5326Bhatnagar, Rakesh, 245Bhattacharya, Sumitra, 3565Bhattacharyya, Chandrabali,

1538Bienzle, Ulrich, 2737Bille, J., 4099Bingyan, Wang, 525Binsztein, Norma, 5190Biosca, Elena G., 1611Birse, Charles E., 3648Bistoni, Francesco, 3476,

3605, 3769Black, Carolyn M., 3369Blair, Robinette, 4607Blake, D. C., Jr., 5384Blake, Milan S., 1346Blanco, M., 2309Blank, Kenneth J., 3540Blaser, Martin J., 1427, 1799,

3440, 5008Blasi, Elisabetta, 3476, 3605Bleiweis, Arnold S., 1547Bliska, James B., 3105, 3914Bliss, Judith L., 1293Bloch, Craig A., 1667Blomberg, Lena, 2526Bloom, Barry R., 2763Bluestone, Charles D., 1950Blum, Paul, 411Bockemuhl, Jochen, 534Bockenstedt, Linda K., 2104,4696

Bodey, Gerald P., 1268Bohach, Gregory A., 4254Bohm, Rudolf P., Jr., 3047Bohne, Wolfgang, 1141Bohnet, Sabine, 3060Bohnsack, John F., 1421, 2334Boltin, Beverly, 1900Boman, Anita, 2978Boman, Hans G., 2978Bondada, Subbarao, 2238BonDurant, R. H., 1385Bonventre, Peter F., 793Boom, W. Henry, 1105, 5410Booth, Roger J., 1509Boquet, Patrice, 5147Bordun, Anne-Marie, 764Borg-von-Zepelin, Margaret,4398

Borland, Robert, 4473B6rlin, Patrick, 4818Borre, Martin, 103Borriello, S. Peter, 751Borst, Deborah W., 5421Bouchara, Jean-Philippe, 4767Boude, Monique, 2732

i

ii AUTHOR INDEX

Boulnois, Graham J., 2505Bourguin, Isabelle, 2082Boushira, Michele, 3791Bout, Daniel, 2082Bouvet, Jean-Pierre, 3597Bouwer, H. G. Archie, 3756Boux, Heather, 2316B0vre, Kjell, 1909Bowen, W. H., 3811Bower, James H., 2493Boyd, Beth, 3886Boyd, D. L., 1453Boyko, Stephanie A., 1098Boyle, Michael D. P., 1378,

3696Brade, Helmut, 3216, 3863,

4514Brade, Lore, 3216, 4514Bradley, Gregory A., 3466Brady, L. Jeannine, 1547Braga, Lucia L., 1772Bragg, Sandra L., 2030Brandt, Mary-Ann, 81Braswell, L. D., 1453Brauburger, Jens, 4915Brautigam, Stilla, 4560Brautigam, Wolfgang, 4560Bray, Mari V., 1586Breiman, Robert F., 3369Bremell, T., 3879Brennan, Patrick J., 338Briaire, Jan, 947, 3688Bridgewater, Jennifer, 4240Britigan, Bradley E., 5049Britton, Warwick J., 4828Britton, W. J., 135Brockman, Denise K., 356Brooks, Carol N., 2891Brooks, L. A., 2145Brown, A. J. P., 4263Brown, David H., 4793Brown, Eric J., 1889, 2334Brown, J. Edward, 3958Brown, Mary B., 633, 2985Brown, M. R. W., 3503Brown, Thomas A., 940Brown, Wendy C., 236, 3273Brubaker, Robert R., 13, 23,

32Bruderer, Thomas, 2937Brumfitt, W., 8Brunham, Robert C., 1117,

2273Brunswick, Mark, 1722Brunton, J., 4085Brunton, James, 448, 3382Bryant, Amy, 1194Bryla, Dolores, 3678Bryla, Dolores A., 1023Brys, Lea, 3098Bubbers, J. Eric, 3873Buchanan, Kent L., 2854Buckett, Peter, 4590Buckley, Helen R., 3540Bucklin, Scott E., 3184Buckner, Gerra P., 1964Buhler, John E., 4232Buhler, Thomas, 2505Bujard, Hermann, 40, 3490Bull, Christof, 2513Bull-Henry, K., 350Buret, A., 671Burggraaf, Jan D., 1835

Burghoff, Robert L., 1293Burke, John F., 3342Burkhardt, Harald, 2513Burmeister, J. A., 2891Burne, R. A., 3811Burne, Robert A., 1259Bums, Drusilla L., 335Burris, Jennifer A., 3392Burrows, Lori L., 5001Butcher, Wade G., 4119Butron, Betzabe, 3994Butt, Brian M., 2558Butterworth, Anthony E.,4984

Butzler, J.-P., 289, 4885

Cabiaux, Veronique, 2200Calderone, Richard, 4675Calderone, Richard A., 2662Calderwood, Stephen B., 1098Caldwell, Harlan D., 4406Calhoun, MacDonald C., 3496Califano, Joseph V., 2400Callahan, Heather L., 1157Callister, S. M., 4367Camprubi, Silvia, 852Camus, Daniel, 1164, 3933,

4863Canil, Christina, 2755Cao, Ping, 5008Cappuccinelli, P., 1786Caprioli, Alfredo, 4909Capron, Andre, 360Carbone, F. R., 5374Carcy, Bernard, 734Cardenas, Lucia, 4629Carlier, Yves, 4925Carlos, Steven J., 4582Carlucci, Sergio, 439Carniel, Elisabeth, 2717Carpick, Bruce W., 4710Carrasco-Marin, Eugenio,3664

Carrel, Stefan, 378Carruba, Giuseppe, 1500Carstensen, Olaf, 3060Carter, Mark, 2493Case, Marian C., 1062Case, Stephen E., 3403Casey, Thomas A., 2249Cassone, Antonio, 1500, 4105Castro, Mario, 4302Castro, Rodrigo, 2937Catanzaro, Antonino, 663Caufield, Page C., 4119Cavelier, Lucia, 284Cenci, Elio, 3769Cervia, Joseph S., 1330Cesbron-Delauw,

Marie-France, 360Ceselski, Sarah, 2357Ceska, Miroslav, 602Chaby, Richard, 3616Chaffin, W. LaJean, 3449Chakrabarti, Ganes, 3565Chakraborty, Trinad, 2793,

3073Champagne, Catherine M. E.,

3137Champsi, Jamila, 3093Chang, A., 4293, 5035Chang, Ju-Kay, 1421Chang, Sandra P., 3403

Chang, Swei-Ju, 5345Chang, Yung-Fu, 2089Chapes, Stephen K., 4013Charboneau, Darlene, 1352Chardes, Thierry, 2082Charoenvit, Yupin, 2493Chaussee, Michael S., 3719Chavarot, Pierre, 742Chavoya, A., 816Chearskul, S., 1149Cheers, Christina, 2626, 2841,4899

Cheever, Allen W., 1288Chen, Cheng-Yen, 4599Chen, James Yok-Jen, 391Chen, Jen-Yang, 1563, 4689Chen, Wangxue, 97, 3548,

3928, 5406Chen, Yi-Ywan M., 2602Cheng, Shuk Han, 4501Cheng, Xiaoxing, 2253Cheng, Xun, 498, 1365Chengappa, M. M., 2089Cheong, Yuet-Meng, 4527Cherniak, R., 1340, 2879Chi, Emil Y., 478, 4835Chia, Jean-San, 1563, 4689Chiang, Thomas J., 3724Chihara, Kazuo, 3117Chikami, G. K., 705China, Bernard, 3129Chippendale, G. R., 350Chiu, Chung-Yin, 5345Choi, Yvonne, 1867Chollet-Martin, S., 4553Chong, Pele, 1867, 2316, 2653Chonmaitree, Tasnee, 1132Chougnet, C., 4498Christner, Robert F., 4232Christopher-Hennings, Jane,

2304Chu, Chiayung, 3678Chung, Chi Y., 1772Cieplak, Witold, Jr., 1764Cinco, Marina, 3081Ciolli, L., 5225Clancy, R. L., 671Clark, Burton D., 4356Clark, C. G., 4085Clark, M. Ann, 4001Clark, W. B., 2011Clark-Curtiss, Josephine E.,

1004Clawson, Dawn, 1352Clemens, Daniel L., 2803Clements, John D., 4629Clyne, Marguerite, 4051Cocito, Carlo, 439Cockerill, Frank, III, 3382Cockle, Stephen, 2316Coe, Christopher J., 1593Coffey, Tracey J., 4382Cogniaux, Jacqueline, 2687Cogswell, Frank B., 3047Cohen, Dani, 2390, 3678Cohen, Jonathan, 1650Cohen, Paul S., 1293, 2526Cole, A. T., 4885Cole, Garry T., 3449Cole, P. J., 2419, 2848Cole, Robert L., 3761Coleman, Lisa A., 5115Collaco, Christopher R., 4427

Collier, R. John, 2200Collins, Bryan, 3449Collins, J. G., 1453Colomb, Maurice G., 5134Colombo, M. M., 1786Comstock, Laurie E., 423Conlan, J. Wayne, 2703Conley, Frances K., 2284Conradt, Peter, 2154Conseil, Valerie, 3933Conway, Mandi D., 3047Conway, Patricia L., 2526Cook, Susan, 884Cooney, Brad J., 4682Cooney, Jakki, 768Cooper, Brian W., 1593Cooper, Chester R., Jr., 2069Copass, Michael C., 3914Cope, Leslie D., 2003, 3966Cope, Patricia A., 4814Copelan, Edward A., 2357Corbeil, L. B., 1385Corbeil, R. R., 1385Cornelis, Guy, 71Cornelis, Guy R., 3129Cornillet, P., 4980Corradin, Giampietro, 3064Costerton, J. William, 777,

1743Coulton, James W., 3334Couto, Marcelo A., 2991Covaro, Gail, 4126Cover, Timothy L., 1427,

1799, 5008Cowell, James L., 1950, 2211Cowman, R. A., 182Cox, Rebecca A., 1895Cox, Teresa M., 1288Crabb, Joseph, 4079Crawford, D. L., 2520Crawford, Jack T., 2708Crawford, Robert M., 689Creasey, A. A., 4293, 5035Cripps, A. W., 671Crisanti, Andrea, 2347, 3490Croize, Jacques, 5134Crosa, Jorge H., 3228Cross, Alan S., 975, 2741Crouch, Rosalie K., 1157Crowe, Sheila, 448Crowley, Paula J., 1547Cruce, D. D., 1232Crusiaux, Alain, 4280Cryz, Stanley, 3994Cryz, Stanley J., Jr., 975,

1149Cuevas, William A., 4310Cullen, Constance, 793Cundell, D. R., 2419, 2848Curry, S. B., 350Curtiss, Roy, III, 1004, 1859Cushion, Melanie T., 4801Cutler, Jim E., 2578, 3244Czeczulin, John R., 3429Czuprynski, Charles J., 3068,

3739

Daddona, Peter E., 512, 1756Daeron, Marc, 4925Dahan, David, 3334Dahlgren, U. I., 3952Daigle, F., 836Dallas, Mary Miller, 4415

INFECT. IMMUN.

AUTHOR INDEX iii

Dallo, S. F., 816Dalmasso, Agustin P., 2532Dalsgaard, K., 268Daly, Thomas M., 2462Daniels, Maggie, 4382Danve, Bernard, 486Dao, My Lien, 5021Darcy, Francoise, 360Darji, Ayub, 3098Das, Pranab K., 1835D'Ascenzi, Sandro, 1272Dasgupta, Mrinal K., 1743da Silva, Wilmar Dias, 3656Da Silveira, Jose Franco,

3636, 4196Datta, Manjula, 4501Daugherty, Robin, 3412Daugherty, Shannon, 5078Davenport, M. P., 135Davies, R. J., 2419Davis, Terry L., 5286Davis, William C., 4254Day, Luz, 3412Day, Noorbibi K., 525de Almeida, Alzira M. P.,

2717Dean-Nystrom, Evelyn A.,2249

de Azavedo, J. C. S., 4085de Azavedo, Joyce, 3382De Baetselier, Patrick, 3098Debeaupuis, Jean-Paul, 4767De Bernardis, Flavia, 1500de Boer, J. P., 4293, 5035De Bruyere, Marc, 3129DeBuron-Connors, Isaure,

4962De Cassia Ruiz, Rita, 3636Decazes, Jean-Marie, 1596de Chastellier, Chantal, 3775Deepe, G. S., Jr., 714Degagne, Pat, 1735de Graaf, F. K., 4518de Graaf, Frits K., 800De Graaf, L., 4167De Grandis, Stephanie, 4510De Groote, Dona, 4280Deighton, Margaret, 4473De La Cruz, Montserrat, 4857de la Maza, Luis M., 498,

772, 1365Delaunoy, Christian, 1164Del Cacho, Emilio, 4857de L'ero, Gabriella Cipollaro,

155Del Giudice, Giuseppe, 3064Deloron, P., 4498Delplace, Patrick, 3933De Mol, P., 289De Montclos, Henri P., 2732Denich, Kenneth, 1091, 4818Dennis, Vida A., 3047Denoyel, Gerard A., 2732Deponte, Kathy, 2104de Repentigny, Louis, 3791Derouin, Francis, 1596Dertzbaugh, Mark T., 48, 384Desbordes, B. C., 350Deslauriers, Manon, 1040De Smet, K. A. L., 2145Desmonts, J. M., 4553de Sousa, Joao Paulo

Carvalho, 5286

de Souza, Mark S., 1814, 4493Desowitz, Robert S., 988Desperrier, Jean-Michel, 5106De Taisne, Charles, 3933Detrick, Melinda S., 418Devalia, J. L., 2419Devi, Shamala, 4527Devine, Dana V., 1829de Wit, Tobias F. Rinke, 3642Diallo, Moctar, 3490Diamond, Michael S., 2919Dias, Feliciano, 5097Diaz, Humberto, 2030Dickens, Sarah M., 4360Dickinson, Douglas P., 5181Dierich, M. P., 1395Dietz, Klaus, 40DiFabio, Jose, 4760Dillon, Harrison F., 5426Dillon, M., 350Dinarello, Charles A., 926,

3342, 4356Di Padova, Franco E., 3863Dobbelaere, Dirk A. E., 236,

3273Dockrell, Hazel M., 3724Dockrell, H. M., 2145Dockter, Micheal E., 785Dodson, James M., 1772Doebbeling, Bradley N., 5049Doggett, Teresa A., 1859Dohi, Sekiko, 764Doi, Toshinori, 1980, 3552Dolan, Matthew J., 1895Domann, Eugen, 3073Domer, Judith E., 2122Donelli, Gianfranco, 3988Dong, Zhao Ming, 5067Donnenberg, Michael S., 2755Donohue-Rolfe, Arthur, 1098Donta, Sam T., 3282Dorey, E., 2419Dorio, Raymond, 3149Doumbo, Ogobara, 40, 3490Doyle, Patricia S., 4079Doyle, Thomas J., 504Doyle, William J., 1950Drouet, Emmanuel B., 2732Drowart, Annie, 2687Drumm, Brendan, 4051Duane, Peter G., 1352, 4392Dubois, B., 4498Dubremetz, Jean Francois,

1169Duchow, Jochen, 4280Dugal, France, 4785Duncan, J. Robert, 170Duncan, M. J., 2260Duncker, Hans P., 3143Dunkley, M., 671Dunn, Pamela L., 2703, 5302Dunne, David W., 4984Dusek, David M., 940Dyer, David W., 204, 2698Dyer, Roy B., 4427Dytoc, M., 4085Dytoc, Marlene, 448, 3382Dziegiel, Morten, 103

Eastcott, Jean, 2899Ebenbichler, C., 1395Ebrahim, Jalal Seyed, 4523Eckhardt, Thomas, 2211

Eckmann, Lars, 4569, 5231Edgerton, M., 2644Edwards, Morven S., 1415,

2866Eerenberg, A. J. M., 4293,5035

Egan, William, 3678Egli, Christine, 1694Eidels, Leon, 994Eiffert, Helmut, 4523Eisenhauer, Patricia B., 3038Eisenstein, Barry I., 1320Elbim, C., 4553El Bouhdidi, Ayachi, 4925Elgavish, Ada, 3304Eling, W. M. C., 303Elkins, Karen L., 823Elliott, John, 3369Ellison, Richard T., III, 719Ellner, Jerrold J., 338Elm, Joseph, 988Elson, Charles O., 48, 384,

4272, 4637Ely, Therese, 1756Emmrich, Frank, 2513Engel, Andreas, 5413Engels, Anne, 4863Engleberg, N. Cary, 1320Engstrom, Suzanne M., 5115Enright, Frederick M., 1Erdile, Lorne F., 81Ernani, Frederick P., 2596Erre, G., 1786Erroi, Annalaura, 4356Espevik, Terje, 1917Esteban, Mariano, 3351Etges, Robert J., 3730Evans, Martin E., 512Evans, Patricia, 4590Everest, P. H., 4885Ezkurra, Pilar A., 4842

Faber, William R., 1835Facklam, Richard R., 3369Fagon, J. Y., 4553Fahim, Raafat, 2653Faille, Christine, 1164Fairbrother, J. M., 836Fairbrother, John M., 2453Falbo, Vincenzo, 4909Falkow, Stanley, 1846, 2233,

2486, 3914, 4654Fandeur, Thierry, 4469Fang, Ferric, 5231Fang, Guodong, 764Fang, Inghwa S., 3873Fantuzzi, Giamila, 4356Faradji, Albert, 1082Farinha, M. A., 1571Farley, Monica M., 1559Fasano, Alessio, 764, 4462Fattom, Ali, 1023Fauchere, Jean-Louis, 3440Fayer, Ronald, 2377Fedorko, Ludwik, 448Feingold, Kenneth R., 3496Feistauer, S. M., 1996Feldmann, Renata-Chandrika,

2945Ferchal, Francoise, 1596Ferdows, Mehdi S., 2192Ferreira, Paula, 1881Ferretti, J. J., 1121

Ferretti, Joseph J., 1246, 3719Fertel, Richard, 4333Ficht, Thomas A., 3785Fick, Robert B., Jr., 5049Fidel, Paul L., Jr., 1990, 4202Fielder, Thomas J., 772Fierer, Joshua, 4569, 5231Figueiredo, Elizabeth N., 2131Figurski, David H., 3544Fikrig, Erol, 423, 1814, 2553Findlay, Kirk A., 4848Fine, Daniel H., 3544Finkelman, Fred D., 1288Finkelstein, Richard A., 5271Finlay, B. Brett, 2755, 4489,

5231Fiorentini, Carla, 3988Fiorucci, Fabio, 439Fischer, Anja, 40Fischer, Steven H., 3761Fisher, Susan J., 4434Fitzgerald, David, 1023Fitzgerald, Thomas J., 4743Fives-Taylor, Paula, 1016Fives-Taylor, Paula M., 1239,

4933Flanigan, Timothy P., 4888Flavell, Richard A., 423, 2553Fleer, A., 4167Flegel, Willy A., 5140Fleischer, Bernhard, 2445,

4507Flood, Patrick M., 1040Flower, Robert L. P., 371Foerster, Birgit, 1636Fojtasek, Marvin F., 4607Fontaine, Annick, 3625Fonzi, William A., 3648Forney, Larry J., 3375Forsgren, Arne, 4546Forstner, J. F., 3157Fortier, Anne H., 689, 823Foster, John W., 4489Foster, Lisa-Anne Agiato,

2698Foster, Timothy J., 2172Foster, T. J., 768Fountain, Michael W., 573Fox, Barry, 2357Fox, James, 1601Fox, J. G., 2309Francis, David H., 2304Francis, K. P., 640Franco, Fulvia R. S., 4196Frangipane, Joseph V., 1657Frank, Dara W., 307Frank, Michael M., 3578Frankel, Gad, 4208Franklin, Craig L., 876Franklin, Heather L., 2960Franzke, Stephan, 2662Franzon, Vicki L., 3032Franzoso, G., 1523Frederick, Bart, 1756Freeman, Collin D., 1593Frehel, Claude, 3775Freiberg, Rachel A., 4937Freitag, Nancy E., 2537Freudenberg, Marina A., 970Freymuller, E., 1152Friedlander, Arthur M., 245Friedman, Herman, 2216,

4027, 5056

VOL. 61, 1993

iv AUTHOR INDEX

Fries, L. F., 1251Friman, V., 3998Frisach, M. F., 1432Froberg, M. Kent, 4743Frontin, K., 350Frulh, Klaus, 40, 3490Fujihara, Yasuko, 910Fujihashi, Kohtaro, 4272Fujii, Nobuhiro, 5309Fujioka, Toshio, 933Fujita, Masashi, 1334Fujita, Miki, 4350Fujita, Takuo, 3117Fukada, Masako, 5044Fukui, Kazuhiro, 4878Fukushima, H., 2011Fukushima, Jun, 1400Fukushima, Kazuo, 323Fukutomi, Y., 4173Fulford, Anthony J. C., 4984Furgang, David, 3544Furney, Synthia K., 338Furuya, Nobuhiko, 2468

Galanos, Chris, 970Galdiero, Francesco, 155Galdiero, Massimiliano, 155Galen, James E., 4462Galgiani, John N., 1895Gallagher, M. P., 640Gallay, Philippe, 378Gambello, Michael J., 1180Gandolfo, Giuseppe M., 439Ganeshkumar, N., 981Gao, Qingshen, 2383Garay, Esperanza, 1611Garbe, Thomas, 260Garcia, Marie Isabelle, 5106Garcia, Pilar, 926Garcia-del Portillo, Francisco,

4489Gardufno, Rafael A., 3854,4582

Garg, Manju, 2238Gargan, R. A., 8Gariepy, Jean, 4710Garon, Claude F., 1460, 2611Garringer, Todd, 4607Garza, Orlando, 3942Gazlig, Thomas, 2793Gbarah, Awni, 1687Gebhart, C. J., 5237Geelen, Sibyl, 1538Gelfand, Jeffrey A., 3342Geller, Arthur M., 785Gemski, Peter, 2741Genco, Robert J., 2369, 3570Gendron, Nathalie, 3791Geoffroy, C., 1055Georgopoulos, A., 1996Gerlach, Dieter, 2727, 3719Gerlach, Gerald-F., 565Gerstenecker, Bernhard, 5315Gessani, Sandra, 4105Gessner, Andr6, 4008Gheorghiu, Marina, 742Ghezzi, Pietro, 4356Gibbons, James J., Jr., 2211Gibert, C., 4553Gibert, Maryse, 5147Gibson, Helen, 3403Gibson, Ronald L., 478Giehl, Theodore J., 719

Gielkens, Arno L. J., 947,3318, 3688

Gigliotti, Francis, 97, 2886,5406

Gilbert, G. L., 1531Gilks, Charles, 4382Gillespie, S. H., 3076Gilliam, T., 350Gillin, Frances D., 520, 5394Gilmore, Keeta S., 1246Gilsdorf, Janet R., 3375Giorgio, Selma, 2131Giovarelli, Mirella, 4356Girard, Robert, 3616Giron, Jorge A., 1126Gladigau, Irene, 800Glauser, Michel Pierre, 378Glew, M. D., 903Glew, Robert H., 4232Gnocchi, Paola, 4356Godinho, Eliane B., 2266Godoy, Veronica G., 4415Goebel, Werner, 162Gold, B. D., 2632Gold, Benjamin, 448Goldberg, Marcia B., 4941Golding, Basil, 1722Goldman, Michel, 4280Goldman, William E., 3123Goldmann, Donald A., 551Golenbock, Douglas T., 4452Gomes, T. A. T., 1152Gomez, Maria J., 4105Goncharoff, Paul, 3544Gonzalez, Jose C., 970Good, Robert A., 525Gooday, G. W., 4263Goodman, Jesse L., 4777Goodman, Simon, 2513Gooley, Andrew, 4828Goossens, H., 4885Gorden, Jed, 364Gordon, Valery M., 3392Gorenflot, Andre, 734Gotschlich, Emil C., 3703Gotto, John W., 2211Gottschau, Adam, 103Gotuzzo, Eduardo, 3994Goudeau, Alain, 4112Gougerot-Pocidalo, M. A.,

4553Gounon, Pierre, 5106Gow, N. A. R., 4263Goyert, Sanna M., 3149Graham, Brett, 5426Grandison, Prudence M., 1509Granfors, Kaisa, 5261Granger, Donald L., 689Grant, Christopher C. R.,

1764Gras, Marie France, 3334Grass, Susan, 4017Grau, Georges E., 4182Graves, Dana T., 4622Gray, Lynn D., 2681Graybill, J. R., 714Grayston, J. Thomas, 2037Greco, F., 5225Green, Bruce A., 1950Green, Israel, 1950Green, Shawn J., 689Greenfield, R. A., 2520Greenspan, D., 4263

Greenspan, J. S., 4263Greenwalt, Dale E., 2229Greenwel, Patricia, 3985Griffith, Ronald W., 2813Griffiths, Gail E., 1346Grillot, Didier, 3064Grimaud, Jean A., 2732Grimm, Elizabeth A., 830Grollier, Ghislaine, 3440Gross, Mitchell, 5062Gross, Uwe, 1141Grossman, Douglas, 3175Grubbs, B. G., 3556Grunfeld, Carl, 3496Gu, Xin-Xing, 1873Gu, Yan, 3047Gubler, Duane J., 3047Gueirard, Pascale, 4072Guenounou, M., 4980Guerrant, Richard L., 764Guillen, Nancy, 1048Guilvout, Ingrid, 2717Guinand, Micheline, 5417Guiney, Donald, 5231Guiso, Nicole, 486, 3583,

4064, 4072Guiyoule, Annie, 2717Gulig, Paul A., 504Gunther, Elisabeth, 2727Gupta, Radhey S., 4225Gustafsson, Mikael, 1406Gutgsell, Nancy S., 3416Gutierrez, Natalie, 551Guttormsen, Hilde-Kari, 4734Guy, Rebecca A., 1553Guzman, Carlos A., 573Gyles, Carlton L., 4510

Habara-Ohkubo, Akemi, 1810Hachem, Ray, 1268Hack, C. E., 4293, 5035Hacker, Jorg, 544, 2108, 2505,

3060, 4480Hackett, Sean, 1194Hackstadt, Ted, 1926Hadding, Ulrich, 2945Haffner, Christof, 3073Hahn, Pauline E., 2912Haidaris, Constantine G.,

1940, 2886Haidaris, Patricia J., 2886Hakansson, Sebastian, 71Hall, Andrew C., 4326Hall, B. Fenton, 3656Hall, Raymond T., 1829Hall, Robert, 1126Hall, Robert H., 4326Hamada, Atsuo, 2242Hamelmann, Christoph, 1636Hamilton, Bette, 4743Hamilton, Thomas A., 2325,

3518Hamilton, Thomas R., 4743Hamilton-Miller, J. M. T., 8Hammer, Carl H., 3578Han, Hyemee, 2474Han, Yongmoon, 2578, 3244Hanada, Nobuhiro, 2096Hanazawa, Shigemasa, 5219Hancock, Robert E. W., 1694,

3287Handelsman, M. Y. C., 4085

Handman, Emanuela, 220,3459

Hanisch, Franz-Georg, 2108Hanna, Philip C., 3429Hansen, Eric J., 1867, 2003,

3375, 3966, 5157Hansen, George M., Jr., 4493Hansen, Morten B., 1069Hanson, L. A., 3952Haque, Azizul, 4863Haque, Salma, 1040Hara, Hiroaki, 4878Hara, Kohji, 3533Harboe, Morten, 1730, 1835,

2687Hardie, J. M., 3076Harding, Clifford V., 4848Harel, J., 836Harel, Josee, 2453Haritani, Makoto, 1750, 2257,

4153Harkness, Robin E., 1867Harmon, Cecily C., 1964Harmsen, Allen G., 97, 2886,

3548, 3928, 5406Harn, Donald A., 146, 3003Harp, James A., 3548, 3928Harris, David, 260Harris, Hobart W., 3496Harris, Theresa O., 2059, 3175Hart, Mark E., 919Harwig, Sylvia S. L., 2991,

3038Hasan, Rumina S., 3724Hashimoto, Ann, 3403Hashiro, Carole, 3403Hasl0v, Kaare, 56Hasty, David L., 4208Hausman, Sally Z., 335Havell, Edward A., 97, 1630,

3548, 5174Hawkey, C. J., 4885Hayek, Michael B., 5049Hayes, Mark P., 3222Hayes, Stanley F., 1926Hazell, Stuart, 1601Hazen-Martin, Debra, 1157Hazlett, Fred E., Jr., 1105Hazlett, L. D., 5164Healey, Mark C., 1482Heath, Andrew W., 4818Heath, Steve, 3656Hechemy, Karim E., 4485Hedges, Spencer, 602Heeg, Holly, 793Heegaard, P. M. H., 268Heesemann, Jurgen, 534,

1141, 2513, 2585Heilmann, Carsten, 432Heinzen, Robert A., 1926Heiss, Linda Nixon, 3123HeI3ler, Regina, 4915Helmby, Helena, 284Helminen, Merja E., 2003Hemelhof, W., 289Hendriks, Jos H. I. M., 800Hendrix, Laura R., 470Henrich, Birgit, 2945Henricson, Beth E., 2325Hensler, T., 1055Heremans, Hubertine, 3098Hermann, Elisabeth, 4507

INFEC-F. IMMUN.

AUTHOR INDEX v

Hernandez-Frontera,Evaurely, 2116

Heron, Iver, 56, 844, 2408Herva, E., 2196Herzog, Norbert K., 4427Hetherington, Seth V., 5157Hetsko, Michael L., 5394Heumann, Didier, 378Heussler, Volker T., 236Heymer, Berno, 2585Hibbs, John B., Jr., 491Hibi, Eiko, 5181Hickman, Carole J., 1674Hiemstra, Pieter S., 3038Higgins, Gloria, 1194Highlander, Sarah K., 3942Hildebrandt, Johannes, 2015Hill, Harry R., 1421, 2334Hill, Joseph O., 5302Hill, Priscilla J., 4045Hines, Murray E., II, 1Hines, Stephen A., 3511, 4929Hinkelmann, K. H., 2891Hinrichs, David J., 3756Hirakata, Yoichi, 2468Hiramune, T., 2270Hirsch, Shannon, 2670Hirst, Barry H., 4001Hocini, Hakim, 3597Hoffman, Matthew P., 1940Hoffman, Orleen A., 4302Hoffman, Stephen L., 2493,

5062Hoffman, Thomas, 1722Hofmann, Andreas, 2182Hofmann, Heidelore, 4158H0gasen, Anne KirstiMyrvang, 1779

Hohenstein, Peter, 4217Holden, David W., 1650Hollander, H., 4263Hollingshead, Susan K., 2277Hollyer, Taras, 1735Holm, Arne, 56, 2408Holmberg, Cynthia F., 2899Holmgren, J., 3952Holst, Otto, 4514Holt, Stanley C., 588, 596,

3562Homer, Karen A., 295Hondalus, Mary K., 2919Hook, Magnus, 2479Horiguchi, Yasuhiko, 3611Hormaeche, Carlos E., 3981Horstmann, Rolf D., 1636Horwitz, Marcus A., 2803Hosaka, Yasuo, 332Hoschutzky, Heinz, 544, 2505Howard, Dexter H., 1468Howard, Maureen, 4818Howard, Randall F., 2960Howeedy, Ali, 3559Hoyle, Brian D., 777Hoynowski, Steve M., 4013Hsu, Tsuey-Ying, 1563Hu, Li-Tai, 2563Hu, P.-C., 1523Hube, Bernhard, 3240Hubner, Johannes, 551Hudson, Michael C., 1259Huesca, Mario, 448, 2474,

2632Hufnagle, Wendy O., 2059

Hughes, Carrie A. Norton,5115

Hughes, Walter T., 619Hui, George S. N., 3403Hull, Richard A., 884Hulse, Michelle L., 4835Hultenby, Kjell, 5351Human, Liset G., 2122Hundt, Erika, 892Hunt, Robert E., 391Huntenburg, Carolyn C., 3873Hunter, Christopher A., 4038Hunter, Robert L., 2296Hunter, Sophie E. C., 3958Huntley, James S., 4326Hurley, David J., 2304Hurst, Steven F., 2030Husar, S. D., 2340Husmann, Linda K., 5426Hussain, R., 2145Hussain, Rabia, 3724Husson, Cecile, 4280Husson, Marie-Odile, 2694Huygen, Kris, 2687Hviid, L., 268

landolo, John J., 919, 4013Ibsen, Per H., 56, 2408Igarashi, Hideo, 5252Iglewski, Barbara H., 1180Iizawa, Yuji, 3739Ijiri, Sumiko, 3552Imanishi, Ken'Ichi, 3922Incani, R. Nino, 3003Inman, John, 1722Inoue, Masakazu, 2096Inselburg, Joseph, 2041, 2048Inzana, Thomas J., 1682Irwin, Michael Y., 3648Isberg, Ralph R., 3907Iscaki, Sylvio, 3597Isetta, Anna, 4356Ishige, Masamichi, 525Ishii, Norihisa, 1400Ishikawa, Hitoshi, 91, 1750,

2257Ishimoto, Karyn, 1371Ishiyama, Shunji, 1307Isobe, Yutaka, 2096Iteman, Isabelle, 2717Ivanyi, Juraj, 260Iwanaga, Masaaki, 5398

Jackson, James V., 1496Jackson, L. A., 4338Jackson, Raymond J., 4272Jacobson, Susan, 3901Jacquemin, Etienne R., 2203Jacques, M., 836Jacques, Mario, 4785Jacquinot, Pierre Marie, 1164Jagusztyn-Krynicka, E. K.,

1859Jagusztyn-Krynicka, Elzbieta

K., 1004Jakobsen, P. H., 268Jalkanen, Sirpa, 5261James, Eric R., 1157James, Olive, 1867Jamieson, G. A., 2229Jamil, Sarwat, 3724Janatova, J., 1395Jann, Klaus, 544, 2505Janoff, Edward N., 4392

Jansen, Bianka, 2793Jansen, Ruud, 947, 3688Janson, Anneke A. M., 3642Janson, Hakan, 4546Jarosik, Gregory P., 3966Jasni, Sabri, 4286Jaton-Ogay, K., 4099Jauris, Sigrid, 2182Jaynes, Jesse M., 1Jeffcoat, M. K., 1453Jeffery, P. K., 2848Jelinkova, Jarmila, 1272Jelonek, Marie T., 5345Jenkins, Mark C., 2377Jenkins, Robert P., 170Jenkinson, Howard F., 3199Jennings, Harold J., 4760Jensen, James B., 2960Jensen, Jean, 3530Jepson, Mark A., 4001Jeurissen, Suzan H. M., 4504Ji, Geun Eog, 1091Jiang, Guo-Zhi, 5044Jiang, Xiaosui, 124Joe, Angela, 3294Joens, Lynn A., 2723, 3466Johnson, Alice R., 2681Johnson, Anthony J., 391Johnson, Barbara J. B., 3047Johnson, David E., 2748, 3422Johnson, Donald C., 970Johnson, James R., 4902Johnson, Joan H., 4888Johnson, Larry, 245Johnson, Lawrence L., 5174Johnson, P. D. R., 1531Johnson, Russell C., 2532,

4777, 5115Johnson, S. R., 1232Johnson, Suzanne M., 3090Joiner, Keith A., 1169, 3656Jolley, William L., 4669Jonas, Christine, 2138Jonas, Daniel, 1715, 4972Jonassen, Tom 0., 1730Jones, Amanda L., 4045Jones, Dana C., 3536Jones, Dorothy, 2245Jones, G. F., 5237Jordens, J. Zoe, 4382Joseph, Sam W., 1674Josephy, P. David, 1442Jouault, Thierry, 4398Joys, Terence M., 1146Juul, Lars, 432

Kaack, M. Bernice, 2289,5214

Kabha, Kisra, 4208Kabok, Z., 2309Kagnoff, Martin F., 4569Kahler, Andrea, 4915Kahu, H., 3952Kajdacsy-Balla, Andre, 3559Kaku, Mitsuo, 2468Kalinna, B., 4716Kalish, Robert A., 2774Kamanga-Sollo, Ernest, 3761Kamau, Timothy, 4984Kamochi, Masayuki, 699Kamp, Elbarte M., 947, 3688Kanaly, Suzanne T., 4929Kanbe, Toshio, 2578

Kane, Anne V., 1098Kane, John P., 3496Kannan, Mathur S., 2618Kansopon, Joe, 2041, 2048Kantengwa, Salome, 1281Kanthakumar, K., 2419, 2848Kantor, Fred S., 2104Kaper, James B., 729, 2755,

3994, 4462Kappler, John W., 3175Karacorlu, Murat, 3047Karakawa, Walter W., 1023Karch, Helge, 534, 4894Karunasagar, Iddya, 162Kasahara, Tadashi, 1307Kaselis, Michael, 4801Kasper, Dennis L., 4760Kasuga, Hidehito, 764Katakura, Ken, 2242Katayama, Sei-Ichi, 457Katayama, Tsuyoshi, 2096Kato, Hiroshi, 5181Kato, Keijiro, 4878Kato, Nobuo, 3164Katz, Jannet, 1964Kaufmann, Stefan H. E., 2154Kawabata, Yoshihiro, 5252Kawai, Makoto, 5044Kawai, Tadashi, 1307Kawamoto, Susumu, 1400Kawamura, Ikuo, 1334Kawata, Yasuhiro, 5219Kay, William W., 3854, 4582Kaye, Susan, 1180Kaye, Susan A., 3886Kayhty, Helena, 3334Kazura, James W., 1105, 5410Keane, Michele, 3250Kegerreis, Kimberly A., 4906Kehoe, Michael A., 1062Kell, Christopher M., 4382Keller, Nathan, 3976Kelly, Charles G., 4590Kelso, Anne, 3459Kemp, Michael, 1069Kern, Peter, 5413Kern, Winfried V., 5413Kernacki, Karen, 2713Kersten, Astrid, 5315Kervella, Michele, 3440Kestler, Hubert, 544Ketley, J. M., 4885Keusch, Gerald T., 1098Kharazmi, Arsalan, 1069Khelef, Nadia, 486, 4064Kiehlbauch, Julia A., 2220Kienle, Zsuzsa, 768Kihlstrom, Erik, 1406Kikuchi, N., 2270Kilian, M., 3998Kilian, Mogens, 4575Kim, Kwang Sik, 975, 3149Kim, Lucy J., 4493Kim, Mary F., 3327, 5123Kimani, Gachuhi, 4984Kimsey, Paul B., 5205Kinden, Darrell A., 876King, C. Harold, 2708King, Judy, 411King, William F., 2899Kinney, Cheryl S., 512Kinomoto, Masamichi, 4005Kipnis, Thereza L., 3656

VOL. 61, 1993

vi AUTHOR INDEX

Kirsch, Thorsten, 2513Kist, Manfred, 5315Kitano, Shigeo, 5219Kiyono, Hiroshi, 4272Kizaki, Takako, 525Klaasen, H. L. B. M., 303Klas, Christiane, 1715Klashinsky, Sandy, 565Klein, Michel, 2316, 2653Klein, Michel H., 1867, 4406Klein, Thomas W., 4027, 5056Klimpel, Gary R., 830Knapp, Bernhard, 892Knight, Lori S., 3873Knutton, S., 4885Knutton, Stuart, 760Ko, Yue-Chau, 1307Kobayashi, Hidemitsu, 4767Kobayashi, Seiichi, 525Kobayashi, Tetsuo, 3533Kobayashi, Yoshinao, 4058Kobisch, Marylene, 4785Koch, Thea, 3143Kocher, Hans P., 3863Kochi, Sims K., 2532Kodama, Hiroshi, 5392Kodner, Carrie B., 5115Koech, Davy K., 1069Koga, Kazunori, 699Koga, Tetsuro, 1371Koga, Toshihiko, 1301, 4344Kohanawa, Masashi, 2786Kohler, Peter, 2937Kohler, Werner, 2727Koita, Ousmane, 40, 3490Kolattukudy, P. E., 2357Kolenbrander, Paul E., 981Koller, M., 1055Koliner, Petra, 2793Komatsu, Toshinori, 64Komisar, Jack L., 391Konig, B., 2545Konig, W., 1055, 2545Konishi, Hisanori, 4147Konkel, Michael E., 1764,

2611Kooi, Cora D., 656Koopman, J. P., 303Korhonen, Timo K., 544, 4480Korn, Alexander, 4915Korting, Hans Christian, 4560Kosma, Paul, 3616Kosunen, Timo U., 3012Kotani, Shozo, 5252Kotb, Malak, 785, 1194Kothary, Mahendra H., 1126Kozel, Thomas R., 2966, 4360Krahenbuhl, J. L., 4173Krajewska-Pietrasik, Danuta,

2479Krakauer, Teresa, 5333Kramer, Michael D., 4158Krammer, Peter H., 1715Krausz, Thomas, 1650Kreft, Burkhard, 3060Kreisberg, Robert, 418Kremsner, Peter G., 2737Kress, Yvonne, 2763Krieg, Suze, 1835Kristensson, Krister, 5129Krivan, Howard C., 2526Krogfelt, Karen A., 1293,

5029

Krohne, Georg, 162Kroll, Hein-Peter, 4915Kropf, Pascale, 3730Kropinski, A. M., 1571Krska, Julie, 411Kruszewska, Danuta, 4188K-Tin-U, Caesar, 1268Kubo, Shigemasa, 4375Kubota, Hiroshi, 4375Kubota, Toshihiro, 933Kuhls, T. L., 2520Kuhn, Hella-Monika, 680Kuhry, Jean-Georges, 1082Kulich, Scott M., 307Kumada, Hidefumi, 5219Kumagai, Mitsuru, 525Kumar, Sanjai, 1958Kumashiro, Ryunosuke, 5388Kunz, Leoni, 4972Kuo, Cho-Chou, 2037Kuramitsu, Howard K., 117,

3745, 3811Kuramoto, Masahiko, 2973Kurihara, Hidemi, 3137, 4878Kurniawan, Agnes, 2827Kurtzhals, J0rgen A. L., 1069Kusters, Johannes G., 5013Kuwano, Koichi, 1700Kuykendall, Randall J., 2030Kwan, Hsueh-Wan, 1563Kwiatkowski, Dominic, 4772

Labigne, Agnes, 5106Lachumanan, Ramkumar,4527

Lacroix, Ronald P., 170Lagergard, Teresa, 1589Lagranderie, Micheline, 742Lagrange, Philippe, 1596Lai, Wayne C., 4615Lal, Altaf A., 2425Lambert, P. A., 3503Lambert, Paul-Henri, 3064Lampe, Mary F., 213Lanata, Claudio F., 3994Landen, Ritva, 4947Lane, Thomas E., 1468Langermans, Jan A. M., 868Lanners, H. Norbert, 3047Lantz, Marilyn S., 4119Laqueyrerie, Anne, 742Larcher, C., 1395La Rosa, Giuseppe, 2347Larsen, Nancy C., 1482Latge, Jean-Paul, 4767Latge, J. P., 4099Lathigra, Raju, 260Latimer, Jo L., 2003, 3966Lauwers, Sabine, 2253Laux, David C., 1293Lawson, Gordon H. K., 4286LeBlanc, Donald J., 2602Le Bouguenec, Chantal, 5106Le Bras, Jacques, 5198Leclerc, Henri, 2694Lee, A., 2309Lee, Adrian, 1601Lee, Brian W., 2618Lee, Catherine A., 1544Lee, Chi-Jen, 5401Lee, J. D., 2357Lee, Jean C., 1853Lee, Jin-Yong, 2369, 3570

Lee, Linda N., 2602Lee, Matt K., 478Lee-Delaunay, Marco B., 760Lees, Andrew, 2493Lefebre, C., 4980Legrand, Dominique, 2694Lehner, Thomas, 4590Lehrer, Robert I., 2991, 3038Lei, Mei-Guey, 910, 1359Leid, R. Wes, 2995Leimeister-Wachter,

Michaela, 3073Leinonen, M., 2196Leinonen, Maija, 2822Leitch, Robert A., 170Lemasters, J. J., 4645Lencer, Wayne I., 5271Leone, Ann O., 512Leong, John M., 2774Leori, G., 1786Lepage, Gilbert, 4398Lepers, Jean Paul, 5198Lepers, J. P., 4498Leppla, Stephen H., 245Lerman, Yehuda, 3678Le Scanf, Cecile, 4469Leung, K.-P., 2011Leung, W. Keung, 1694Levin, Francine C., 3209Levin, Jack, 3209Levine, M. J., 2644Levine, M. M., 1149Levine, Myron M., 729, 3994Levitz, Stuart M., 3818, 4891Leyva-Cobian, Francisco,3664

L'Hostis, Monique, 734Li, Huayi, 1730Li, K. L., 1453Li, Xiuru, 1023Li, Zhong-Ming, 1447Lian, Chang-Joo, 793Lichtman, S. N., 4645Liehl, Ekke, 3863Lim, L. C. L., 4367Limper, Andrew H., 4302Lin, Bo, 3234Lin, Rong-Hwa, 4689Lin, Shu-Wha, 1563, 4689Lincicome, Lisa L., 1098Lind, Christopher D., 5008Lindberg, Alf A., 1211, 1222,5351

Lindgren, Susanne W., 3832Lindsay, Dwight D., 5388Lingwood, Clifford, 448Lingwood, Clifford A., 2474,

2632, 3886Linke, Michael J., 4703Linnig, Monika, 2445Lintermans, Paul F., 2203Linton, Garry, 4615Litteri, Laura, 966Liu, Yannan, 4452Liu, Zhanqi, 2626Livolsi, Paul J., 1853Llorens, Helena, 1611Lo, Reggie Y. C., 4682, 5001Lo, Shyh-Ching, 3327Lockatell, C. Virginia, 2748,3422

Logan, Kathleen S., 3273Lohman, Kenton L., 3351

Lomholt, Hans, 4575Long, Carole A., 2462Loos, Bruno G., 204Loosmore, Sheena, 2316Lopez-Bote, Juan Pedro, 4225L6pez-Guerrero, Jose

Antonio, 4225Lorenzini, Rodolfo, 1500Lory, Stephen, 1371Losonsky, G., 1149Losonsky, Genevieve, 3994Losonsky, Genevieve A., 729Lottspeich, Friedrich, 544,

2505Louie, M., 4085Louie, Marie, 448, 3382Louis, Jacques A., 3730Louise, Chandra B., 3886Lovgren, Ann, 4947Lovgren, Karin, 2639Lovrich, S. D., 4367Low, Martin G., 4947, 5078Lowell, George H., 2390Lowrie, Douglas B., 4501Lowrie, Robert C., Jr., 3047Lu, Hong, 2400Lu, Shuzhuang, 197, 3482Lucas, Bernadette, 4863Lucier, Thomas S., 32Lukehart, Sheila A., 781Lun, Maria Teresa, 3976Lunden, Anna, 2639Lundin, Knut E. A., 5294Luo, Guoyang, 830Lupher, Mark, 4254Lyerly, David M., 2912Lyford, Lisa K., 1040Lynch, Maria E., 1990, 4202Lynn, William A., 4452Lyon, Julie D., 4254

Ma, Din-Pow, 2089Ma, Ying, 3843MacBeth, Kyle J., 1544Macedonia, Jane G., 1288Maclnnes, S. J., 1531MacIntyre, Neil, 4286Maciver, Isobel, 2003, 3966Mack, Julie A., 5279Mackenzie, Donald, 4398Mackie, Rebecca A., 4286Maderazo, Eufronio G., 1593Maeda, Hiroshi, 1980, 3552Magee, Beatrice B., 3240Magee, D. M., 714, 3556Magee, D. Mitchell, 1895Magee, P. T., 3240Maheswaran, Samuel K., 2618Mai, G. T., 559, 4338Mainil, Jacques G., 2203Maiti, Sourindra N., 2453Maizels, Rick M., 2827Majeed, Meytham, 1406Majumdar, Gipsy, 785, 1194Mak, Tak, 5129Makela, P. Helena, 4248Makristathis, A., 1996Malamy, Michael H., 4415Malek, Thomas, 3416Malik, Anita, 5062Mallavia, Louis P., 470Mallik, Kamal Kumar, 3565Mancilla, Javier, 926

INFECT. IMMUN.

AUTHOR INDEX vii

Mancini, Carlo, 3976Mancuso, Giuseppe, 227Manivel, J. Carlos, 4777Manjula, B. N., 3703Mann, Barbara J., 1772Mann, Karlheinz, 2727Manna, Partha Pratim, 3565Manning, Donald S., 4093,4406

Manning, Paul A., 3032Manson, Kelledy, 3351Manthey, Carl L., 2015, 2325,

3518Mantle, M., 2340Mantle, Michele, 4131Marcantonio, Nancy, 2104Marchal, Gilles, 742Marchant, Arnaud, 4280Marconi, Richard T., 2611Marcus, Rachel, 1091Margolis, Neil, 2207Markham, P. F., 903Marko, Michael, 4485Marot-Leblond, Agnes, 4842Maroushek, Nancy, 3068Marques, Guillermo, 852Marquis, H6lene, 3756, 3785Marr, James C., 4254Marrack, Philippa, 3175Marre, Reinhard, 3060Marrs, Carl F., 1909, 3375Martin, Edith, 4972Martin, Louis N., 2289Martineau-Doize, B., 836Martinez-Martinez, L., 4167Marx, John N., 3449Marx, Tim, 2445Masala, G., 1786Masinick, S., 5164Mason, Patricia H., 4906Massad, George, 884Mastroeni, Pietro, 3981Masuda, Tamuro, 5219Masure, H. Robert, 2780Matsiota-Bernard, P., 4980Matsuda, Hiroshi, 2242Matsuda, Morihiro, 3611Matsumoto, Takahiro, 699Matsuo, Kazuhiro, 1173Matsushima, Kouji, 1307Matsushiro, Aizo, 4375Matsushita, Kenji, 5252Matsushita, Osamu, 457Matsu-ura, Ikuko, 1700Matsuya, Tokuzo, 4375Mattsson, E., 4167Mawhorter, Steven D., 5410May, Addison K., 1667Mayer, Jeanmarie, 491Mayfield, John E., 610Mays, John P., 81Mazie, Jean-Claude, 3825Mazzolla, Rosanna, 3476McAdam, K. P. W. J., 3076McBride, Barry C., 1694,

3294, 4139McCarthy, Robert, 1889McClane, Bruce A., 3429McClelland, D. Brian L., 3863McClure, Harold M., 2220McCormack, J. G., 559, 4338McCracken, George H., Jr.,

2003

McDermid, Kevin P., 1743McDonough, Kathleen A.,

2763McElwain, Terry F., 3511McGavin, Mary Homonylo,

2479McGee, Dennis W., 4637McGhee, Jerry R., 4272, 4637McKee, Jeff J., 1509McKee, Mary, 4485McKeever, Declan J., 1486McKenzie, K. R., 135McLeod, Karen S., 3459McMahon-Pratt, Diane, 3351McManus, D. P., 4716McMurray, David N., 142,2116

McNab, Roderick, 3199McOrist, Steven, 4286McVerry, Patrick, 2653McWhinney, P. H. M., 3076Mehigh, Richard J., 13Mekalanos, John J., 5271,5279

Melby, Kjetil, 1730Mellott, Gerald E., 2024Meloni, G. A., 1523Melton, Angela R., 807, 3832Meltzer, Monte S., 689Menard, Robert, 1707Mencacci, Antonella, 3769Meng, Tze-Chiang, 5394Menge, Alan C., 2162Mengozzi, Manuela, 4356Menon, Satish, 4937Merino, Susana, 852Merjan, Antonio J. C., 2131Mertz, Andreas, 2498Messick, Joanne B., 3803Mestecky, J., 2162Metcalf, Eleanor S., 3084Metcalf, Thomas N., III, 2211Metzroth, Bernhard, 2445Meuwissen, Joep H. E. T.,

1936Meyer, Diane H., 1239, 4933Meyer zum Buschenfelde,Karl-Hermann, 4507

Michalek, Suzanne M., 1964,2162, 2277

Michaliszyn, Eva, 3791Michalski, Jane, 4462Michel, Georges, 5417Michetti, Pierre, 5279Michon, Francis, 4760Mihara, Joji, 588, 596, 3562Militzer, Pascal, 742Miller, Louis H., 1958Miller, Richard D., 3416Miller, Shohreh, 2930Miller, V. L., 705Mills, Kingston H. G., 399,

3190Mills-Robertson, K., 350Minagawa, Tomonori, 2786,

2872Minami, Junzaburo, 457Mindell, Joseph, 2200Minnick, Michael F., 4962Mintz, Clifford S., 3416Mirelman, D., 3574Mirelman, David, 1687Mirza, A., 5326

Miscelli, Mary Ann, 1756Mitchen, Tonya K., 5205Mitchison, Denis A., 4501Mitra, MonaLisa M., 1202Mitsuyama, Masao, 1334Miyamoto, Hiroshi, 1972Miyazawa, Yasushi, 596Miyoshi-Akiyama, Tohru,3922

Mizobuchi, Sadao, 457Mizuguchi, Yasuo, 1972Mobley, Harry L. T., 884,

2563, 2570, 2748Mobley, H. L. T., 350Modlin, Robert L., 197, 3482Mody, Christopher H., 464Moffitt, M. Catharine, 3578Mohamadzadeh, Mansour,4972

Molin, S0ren, 5029Molina, Jean-Michel, 1596Molinari, Gabriella, 573Monod, M., 4099Montag, Monika, 534Monteil, Henri, 1082Montplaisir, Serge, 3791Montravers, P., 4553Moody, Susan F., 220Moore, Lillian V. H., 2891Moore, Robert N., 418Moore, W. E. C., 2891Moors, Marlena A., 3540Mooser, Gregory, 4814Morales, Maria AngelesGomez, 2347

Morck, Douglas W., 1743Morfitt, David C., 610Mori, Masashi, 3164Morihara, Kazuyuki, 1400Moriishi, Kohji, 5309Morita, Takashi, 4375Mork, Theyne, 3287Morris, J. Glenn, Jr., 764Morris, Lynn, 3459Morris, Sheldon L., 1074Morrison, Christine J., 2030Morrison, David C., 910, 970,

1359, 3184Morrow, Brian, 1823Morrow, K. John, Jr., 3449Morse, Stephen A., 4599Morshed, Muhammad G.,4147

Morton, Daniel J., 4033Moser, Stephen A., 3123Mosser, David M., 2919Moter, Sabine E., 4158Moudgil, Kamal D., 1509Mountzouros, Ken, 2211Moxley, Rodney A., 2304M'Rini, C., 1432Mu, Hong-Hua, 2834Mukaida, Naofumi, 1307Mulders-Kremers, GeraldinaA. W. M., 5013

Muller, Eugene, 551Muller, Hans-Michael, 2347,3490

Muller, Ingrid, 2266, 3730Muller, Karl-Heinz, 1694Muller, Klaus-Peter, 4915Muller-Klieser, Wolfgang,4972

Mundayoor, Sathish, 2708Munoz, S. R., 4645Munro, Grant H., 4590Munson, Robert S., Jr., 3026,4017

Muotiala, Anna, 4248Murakami, Kazuhisa, 4058Murayama, Yoji, 3137, 4878Murdin, Andrew D., 4406Murphy, J. C., 2309Murphy, Juneann W., 2854,

4750, 5067Murray, Henry W., 1330Murtaugh, M. P., 5237Musser, James M., 4033, 4112Mustafa, Abu S., 5294Muthukkaruppan, V. R., 3017Muthukkumar, S., 3017

Naab, T., 350Naciri, Muriel, 4440Nacy, Carol A., 689, 823Naessens, Anne, 2253Nagai, Sadamu, 1730, 4005Nagata, Kumiko, 64Nahm, Moon H., 5345Naiki, Masaharu, 5309Nair, G. Balakrish, 289Nair, Jaygopal, 1074Nakagawa, Taneaki, 332Nakai, Motoyuki, 1301, 4344Nakajima, Ryohei, 23Nakamura, Kyohshi, 64Nakane, Akio, 2786, 2872Nakao, S., 2260Nakasone, Noboru, 5398Nakazawa, Teruko, 4147Narvanen, Ale, 2822Nasu, Masaru, 933Nataro, James P., 1126Nato, Farida, 3825Nau, Uwe, 892N'Diaye, Maimouna, 40Neblock, Donald S, 1756Neef, Natasha, 4286Neese, Lewis W., 4302Neifer, Stefan, 2737Nesbitt, W. E., 2011Neuhof, Heinz, 3143Neutra, Marian R., 5271, 5279Neve, Pierre, 4280Newman, Joseph V., 1293Newton, Catherine, 5056Newton, Catherine A., 4027Newton, Joseph C., 1Ngeleka, Musangu, 836N'Guyen, Bao Tho, 3129Nibbering, Peter H., 3111Nickell, Steven P., 3250Nicolau, David P., 1593Nicotera, Pierluigi, 3988Nidiry, J., 350Niebuhr, Kirsten, 2793, 3073Niesel, David W., 830, 4427Niewoehner, Dennis E., 1352Nightingale, Charles H., 1593Nikaido, Cayn, 3403Nilsson, L.-A., 4919Nishimoto, Mitsunobu, 1700Nisizawa, Tosiki, 1301Nixdorff, Kathryn, 4915Nkrumah, F. K., 268Nomaguchi, Hiroko, 4005

VOL. 61, 1993

viii AUTHOR INDEX

Noonan, Lisa C., 1509Norgard, Michael V., 1202Normark, Staffan J., 4848Norqvist, Anders, 2434North, Robert J., 2703Northoff, Hinnak, 5140Noya, Francisco J. D., 1415Neess, Are, 4734Nussenzweig, V., 348

Oaks, Edwin V., 1674Oberle, Suzan M., 5245O'Brien, Alison D., 3392,3832

Obrig, Tom G., 3886Ochi, Sadayuki, 3711Ochiai, Kuniyasu, 323Ockenhouse, Christian F.,

2229Ofek, Itzhak, 4208Offenbacher, S., 1453Offredo, Catherine, 3775Oftung, Fredrik, 5294Ogata, Kenichi, 663Ogata, Masanori, 699Ogata, Steven A., 955Ogden, Gary B., 3656Oguma, Keiji, 5309O'Hanley, Peter, 1091O'Hanley, Peter D., 4818Ohara, Naoya, 1173, 4005Ohishi, Iwao, 5392Ohkuni, Hisashi, 5252Ohman, Dennis E., 4208Ohnishi, Hiroaki, 785, 1194Ohnishi, Yuichi, 4375Ohno, Takeshi, 329Ohta, Hirotaka, 4344Ohta, Hiroyuki, 4878Ohta, Michio, 3164Okabe, Akinobu, 457Okada, Mayumi, 2270Okada, Tamami, 323Okahashi, Nobuo, 1301, 4344Okamoto, Munenori, 2786Okamura, Haruki, 64Okazaki, Ken-Ichi, 4058Okithu, Mithuhisa, 5219Okuda, Katsuji, 332Okuda, Kenji, 1400Olah-Winfield, Elizabeth, 5001Olanratmanee, T., 1149Olerup, Olle, 103Oligino, Lyn, 1016Oliveira, Sergio C., 5339Ollert, Markus W., 4560Ollert, Ute, 4560Oloo, Aggrey J., 2425Olsen, Carl E., 2408Olson, Merle E., 1743Olsson, Tomas, 5129Onoe, Kazunori, 525Opal, Steven M., 2741Ordway, Diane J., 1113Orefici, Graziella, 1272O'Reilly, Mark, 3673Orellana, Manuel A., 2284Orencole, Scott F., 4356Orme, Ian M., 338, 1113Orn, Anders, 5129Orr, Nadav, 23900rskov, Frits, 16190rskov, Ida, 1619

Ortiz, Maria Antonia, 4225Osland, Arve, 3642Otogoto, Jun-Ichi, 117O'Toole, Paul W., 768Ott, Manfred, 2505Otterlei, Marit, 1917Ouchterlony, O., 4919Ouin, Valerie, 5106Ouma, John H., 4984Overath, Peter, 4540Owens, Jennie W., 3392Oyston, Petra C. F., 3958

Pace, Tomasino, 4909Padula, Steven J., 5097Paez, Eduardo, 4225Pages, Jean-Marie, 3440Pai, Jenn-An, 3544Pak, Koon Yan, 1756Pakes, Steven P., 4615Pal, Sukumar, 498, 772Pallesen, Lars, 1293Palmer, Guy H., 3511, 4929,

5245Pancholi, P., 5326Panezutti, Helen, 1867Pang, Tikki, 4527Paoletti, Enzo, 3933Paoletti, Lawrence C., 1853,4760

Papanastasiou, Philemon, 2937Pappagianis, Demosthenes,

3090Pappo, J., 2309Papp-Szab6, Erzsebet, 1442Paranchych, W., 1571Paranchych, William, 3527Paranhos-Bacalla, Glaucia S.,4196

Paranjape, Ramesh, 627Paris, S., 4099Park, Jaechan, 4333Park, Moon K., 5345Park, Yoonsuk, 4139Parkkinen, Jaakko, 4480Parnell, Michael J., 4406Parsot, Claude, 1707Partono, Felix, 2827Partridge, Jim, 411Pastan, Ira, 1023Patel, Janak, 1132Patel, Rupal, 295Patel, S., 3076Patrick, Christian C., 619,

5157Paul, John, 4382Paulsen, Hans, 3216Paulsrud, John R., 1315Paxton, William A., 2827Payne, Dean, 3673Peacock, Marius G., 1926Peake, Philip, 4828Peake, P. W., 135Pearce, Edward J., 5381Pearl, Dennis, 4793Pearlman, Eric, 1105, 5410Pedron, Thierry, 3616Pedroso, M. Z., 1152Peetermans, Willy E., 868Peeters, Carla, 4217Peeters, Johan E., 2203, 4440Pei, Zhiheng, 3440Penny, Mary, 3994

Perelle, Sylvie, 5147Perera, Pin Yu, 2015, 2325,

3518Perez-Casal, Jose F., 5426Perfect, John R., 4446Perkins, G. H., 1232Perry, Judith A., 170Perry, Robert D., 32Perryman, Lance E., 4906Pescher, Pascale, 742Pesci, Everett C., 2930Petersen, Carolyn, 4079Petersen, Jesper W., 56, 2408Peterson, Ellena M., 498, 772,

1365Petitbois, Stephane, 3791Petter, R., 3574Pettersson, Annika, 4724Pettersson, Ulf, 284Peyman, Gholam A., 3047Peyron, Francois, 5198Pfeifer, Cheryl, 5231Pfeifer, John D., 4848Pfrommer, Gail S. T., 4360Phalen, Susan W., 142Phalipon, Armelle, 3825Pham, Anne, 4835Phelps, P. C., 350Philipp, Mario T., 3047Phillips, Manijeh, 627Piacentini, Delmar A., 1547Picci, Leonardo, 4909Piccolella, Enza, 439Pickett, Carol L., 2930Piemont, Y., 580Pier, G. B., 559, 4338Pier, Gerald B., 551Pierson, Dorothy E., 1846Piesman, Joseph, 3047Piguet, Pierre F., 4182Pillot, Jacques, 3597Pincus, Seth H., 3761Pipy, B., 1432Pitt, Louise, 391Pitzurra, Lucia, 3605Pizzi, Elisabetta, 4909Pizzo, Philip A., 1185, 4870Plano, Gregory V., 3105Plummer, Francis A., 2273Poelma, F. G. J., 303Pohl, Jan, 1900, 2030Pohl, Pierre H., 2203Poindron, Philippe, 1082Poirot, Christel, 1596Polla, Barbara S., 1281Pollack, Matthew, 512Pollack, Richard J., 2396Pontieri, Eugenio, 1500Ponton, Jose, 4842Poolman, Jan T., 4217, 4724Poolman, J. T., 187Popoff, Michel R., 5147Portnoy, Daniel A., 2537,

3756Pos, Odette, 3111Posteraro, P., 5225Potter, Andrew A., 565, 1793Poulain, Daniel, 1164, 4398Poulsen, Lars K., 1069Poulsen, Lars Kongsbak, 5029Povoa, Marinete M., 2425Powell, Nicholas B. L., 751Poxton, Ian R., 3863

Poyart, Claire, 1576Pozio, Edoardo, 2347Prabhakar, R., 4501Prada, Javier, 2737Pradel, Ingrid, 2182Prado, Valeria, 764Prager, Christiane, 2737Prakash, Sadhana, 3985Prakobphol, Akraporn, 4434Prasad, S. C., 4675Prasad, Sudha M., 2780Preac-Mursic, Vera, 2182Precigout, Eric, 734Preger, Sonja, 2585Prestidge, Ross L., 1509Preston, Michael J., 2713Prevost, G., 580Pritchard, David G., 3234Probst, Peter, 4507Prodinger, W. M., 1395Progulske-Fox, Ann, 940,

1909Pruett, Timothy L., 1667Prummer, Otto, 5413Puccetti, Paolo, 3769Puliti, Manuela, 3605Purcell, Bret K., 1202Purdy, Charles W., 253, 4669Purven, Maria, 1589

Qian, Hong, 5021Qin, Ming Hui, 1972Qoronfleh, M. Walid, 1567Qu, Zhenhai, 1365Quentin, Roland, 4112Quentin-Millet, Marie-Jose,

486Quigley-Reape, Geri, 1950Quinn, Diana M., 371Quintiliani, Richard, 1593Qureshi, Nilofer, 3518

Rabarison, Patrick, 5198Rabodonirina, Meja, 5198Radolf, Justin D., 1202Raeder, Roberta, 1378, 3696Rahim, Zeaur, 1048Rakotomalala, Charles, 5198Raman, Usha A. K., 2304Ramasubbu, Narayanan, 3259Rambukkana, Anura, 1835Ramirez, Marcel Ivan, 3636Ramsay, Graham, 3863Ramsdell, Fred, 1958Ranney, R. R., 2891Ranucci, Lorella, 2347Rao, Savita P., 663Raponi, Giammarco, 3976Rapp, Joseph H., 3496Rasmussen, Kathleen R., 1482Rastogi, Nalin, 5286Ratliff, Timothy L., 1889Raymond-Denise, Agnes, 1048Raynes, J. G., 3076Razafimanantsoa, Ihari, 1576Razanamparany, Marcel, 5198Rea, Thomas H., 197Read, Thomas E., 3496Recchia, Simona, 1272Reckmann, Ingeborg, 2347Reddy, Kasthuri R., 2618Reddy, Lakshmi Y., 1427Reddy, M., 1453Reddy, M. S., 2644

INFECT. IMMUN.

AUTHOR INDEX ix

Redgrave, Bryce, 2578Redhead, Keith, 399, 3190Reek, Frans H., 3318Regassa, Laura B., 1581Reilly, Patricia A., 2211Reiner, Neil E., 3265Reinholdt, J., 3998Reiss, Errol, 2030Remington, Jack S., 2284,

4038, 4126Renia, Laurent, 348Resau, J. H., 350Rest, Richard F., 1657Rey-Ladino, Jose A., 3265Rhinehart-Jones, Tonya, 823Rice-Ficht, Allison C., 236Rich, Robert R., 3175Richards, James C., 170Richardson, Gloria J., 1964Richardson, Mac, 1293Richter, Dania, 146, 3003Ridley, R. G., 268Riesselman, Marcia H., 2578Rietschel, Ernst T., 3863Rikihisa, Yasuko, 3803, 4333Riley, Eleanor M., 103Riley, Lela K., 876Ringwald, Pascal, 5198Rioux, Clement R., 1793Ritter, Angelika, 2505Rivas, Luis, 3351Rivera, Jacinto, 391Rivera, Maria-Teresa, 4925Rizzu, P., 1786Robbins, John B., 1023, 3678Roberson, Jerry R., 4254Robert, Raymond, 4842Roberts, Alan D., 338, 1113Roberts, D. E., 2419Roberts, E. Donald, 3047Roberts, I. S., 2245Roberts, James A., 2289, 5214Roberts, Mary Denton, 2912Roberts, Morven, 4984Robin, Guy, 2390Robins-Browne, Roy M., 764Robinson, John H., 1062Roche, P. W., 135Rockabrand, David, 411Rodda, Stuart J., 4527Rodewald, Ariane K., 4760Rodriguez, Dolores, 3351Rodriguez, Jose F., 3351Rodriguez, Juan-Ramon, 3351Rodzinski, Eva, 2780Roem, D., 4293, 5035Rogers, Howard W., 5090Rogers, Linda M., 2357Rogerson, Brian J., 1630Rohde, Manfred, 573, 2793Roilides, Emmanuel, 1185,4870

Rojkind, Marcos, 3985Rolf, John M., 994Rollinghoff, Martin, 4008Romain, Felix, 742Roman, Miriam J., 4232, 4485Romani, Luigina, 3769Rombough, Charlane, 4131Romeo, Domenico, 966, 3081Ronald, S. L., 1571Rong, Guo Wei, 3149Rong, Lijun, 2537

Rosa, Patricia A., 2207, 3590Rose, R., 5237Roseff, Shelly A., 3818Rosen, Hugh, 1330Rosenau, Agnes, 4112Rosengarten, Renate, 2224Rosenshine, Ilan, 2755Rosenthal, Louis A., 2919Rosol, K., 5164Ross, Allan E., 4902Rossan, Richard N., 2041,

2048Rossi, A., 5225Rossi-Bergmann, Bartira, 2266Rossi-Campos, Amalia, 565Roth, Robert I., 1033, 3209Roths, John, 1586Roths, John B., 1641Rottenberg, Martin E., 5129Rouse, David A., 1074Roux, Jean, 5198Rouyre, Sylvie, 3825Rowe, Alexandra, 4772Rowe, Pamela, 103Rozenberg-Arska, Maja, 3976Rozenblatt, S., 3574Ruan, Maorong, 4546Rubens, Craig E., 478, 4835Rubin, Lorry G., 650Rubino, S., 1786Rubins, Jeffrey B., 1352, 4392Ruble, David L., 391Rudbach, Jon A., 2122Ruddle, Nancy H., 3351Rude, Thomas H., 4446Ruebush, Trenton K., II, 2425Ruiz, Rosa, 3994Ruschkowski, Sharon, 2755Russ, Friedemann, 2154Russell, David G., 338Russell, Michael W., 314,

1964, 2162Russell, R. G., 5384Russell, Robert G., 2748, 3422Russell, Roy R. B., 1246Russell, R. R. B., 1121Russmann, Holger, 4894Russo, Thomas A., 3578, 4415Rutault, Karine, 5417Rutman, A., 2848Ryan, Liv, 1917Ryan, Raymond W., 5097Ryden, C., 3879Ryd6n, Cecilia, 2479Ryser, Jean Etienne, 4182

Saarinen, Leena, 3334Sadoff, Jerald, 3678Sadoff, Jerald C., 2741Sadosky, Alesia B., 5361Sadziene, Ariadna, 81, 2192,3590

Saikku, P., 2196Saito, Atsushi, 332Saito, Hiroshi, 2973Saito, Masayuki, 5309Saito, Saburo, 2242Sajjan, U. S., 3157Saksela, Eero, 3012Sakurai, Jun, 3711, 3958Salazar, Eduardo, 3994Salo, Paula, 2822Saltini, Cesare, 439

Salvador, Astride, 1881Samols, David, 348Sampieri, Alicia, 5097Samsonoff, William A., 4485Samuel, James E., 470, 3392Sanders, Jerry D., 3966Sandlin, Robin C., 3360Sanglard, D., 4099Sanna, Maria G., 3625Sansonetti, Philippe, 1048Sansonetti, Philippe J., 1687,

1707, 3625, 3825, 4941Sartor, R. B., 4645Sarvas, Matti, 3334Sasaki, Ken, 3026Sastry, Parimi A., 3527Sata, Takeyoshi, 699Sathyamoorthy, Venugopal,4326

Sato, Hisaaki, 2973Sato, Keizo, 1980, 3552Sato, Setsuko, 2096Sauerwein, Robert W., 1936Savarino, Stephen J., 1126Sawyer, Robert G., 1667Scannapieco, F. A., 2644Scarselli, Elisa, 3490Schachter, J., 3556Schachter, Julius, 3078Schaible, Ulrich E., 4158Schaller, Klaus, 2662Schauer, David B., 2486, 4654Schauf, V., 5326Schechtman, D., 3574Scheffer, J., 2545Schell, R. F., 4367Schenkein, Harvey A., 2400Schenkman, Rocilda P. F.,898

Schenkman, Sergio, 898Scherer, David C., 4962Schiaffella, Enrico, 3769Schiefer, Hans G., 3143Schieffer, S., 5413Schieken, R. M., 2891Schiff, Deborah E., 975Schiltz, Emile, 2498, 5315Schlott, Thilo, 4523Schmalstieg, Frank, 1132Schmidt, Herbert, 534, 4894Schneerson, Rachel, 1023,3678

Schneider, Robert A., 2249Schneidkraut, Marlowe J.,

3873Schnizlein-Bick, Carol T.,4607

Schreiber, Robert D., 689Schreier, Max H., 3863Schreiner, Helen C., 3544Schrevel, Joseph, 734Schroppel, Klaus, 4008Schroten, Horst, 2108Schuetze, Eberhard, 3863Schultheis, Beate, 1715Schulze-Koops, Hendrik, 2513Schwab, Elisabeth, 2182Schwab, John H., 4535, 4645Schwartz, Benjamin, 3369Schweitzer, A. Nicola, 1516Scocchi, Marco, 3081Scott, Jane V., 2211Scott, June R., 5426

Scott, Phillip, 2952Scott, V. F., 350Scriba, Marianne, 4523Seas, Carlos, 3994Sebo, Peter, 3583Sedegah, Martha, 2493Sedqui, M., 4980Segall, Thomas, 1211, 1222Seguela, J. P., 1432Selander, Robert K., 204Selkirk, Murray E., 2827Sellwood, Richard, 1136Senaldi, Giorgio, 4182Senechal, Serge, 3791Senet, Jean Marcel, 4842Senger, Phillip L., 2558Senpuku, Hidenobu, 1301Sentandreu, Rafael, 3313Seow, W. K., 559, 4338Sewchand, J., 350Sewell, William A., 2834Shaban, Radwan A., 830Shafer, William M., 1900Shaffer, Jeanne M., 781Shahin, Roberta D., 1447Shanks, Kathryn L., 1346Sharma, Ashu, 3570Sharon, Nathan, 1687Shaw, Michael K., 1486Shealy, David J., 1756Shepherd, Mary E., 1900Sher, Alan, 1288, 3656Sheridan, John, 4793Sherman, Marcie R., 4607Sherman, P., 4085Sherman, Philip, 448, 3382Sherman, P. M., 2632Shi, Jiarong, 2089Shi, Ya Ping, 2425Shibano, Yuji, 1400Shigematsu, Akio, 699Shih, Chien-Ming, 2396Shiloach, Joseph, 1023, 3678Shimonishi, Yasutsugu, 289Shinnick, Thomas M., 2708Shinoda, T., 2879Shiozawa, Shunichi, 3117Shirahata, Toshikazu, 1810Shiratsuchi, Hiroe, 338Shiroza, Teruaki, 3745Shnyra, Alexander, 5351Shoberg, Russell J., 423, 3892Shuman, Howard A., 5361Shuto, Ryusuke, 933Sia, Charles, 2653Sidman, Charles L., 1586,

1641Siebeling, Ronald J., 2053Sieck, Thomas G., 3540Siegel, Marshall, 2211Siegel, Scott A., 512Sieling, Peter A., 197Siffert, Jean-Claude, 1082Sikkema, Daniel J., 32Sileghem, Maarten, 3098Silverstein, Richard, 970, 3184Simecka, Jerry W., 2277Simmons, Nicholas L., 4001Simon, Markus M., 4158Simonson, Janet G., 2053Sims, Kim G., 3536Singh, Bhagirath, 3527Singh, Yogendra, 245

VOL. 61, 1993

x AUTHOR INDEX

Sironi, Marina, 4356Sizaret, Pierre Yves, 4112Skamene, Emil, 3775Skettrup, Michael, 432Skinner, Pamela S., 338Skj&k-Brwk, Gudmund, 1917Skobe, Z., 2260Skrzypek, Elzbieta, 3105Skumik, Mikael, 2498Small, P. L. C., 364Smart, Wallace, 3527Smeltzer, Mark S., 919Smidsr0d, Olav, 1917Smith, Abigail L., 1586, 1814,

4493Smith, Daniel J., 2899Smith, Hilde E., 3318Smith, James W., 1315Smith, M. A., 1453Smith, Peter R., 2172Smith, S., 2848Smith, Susan, 4835Smits, Mari A., 947, 3318,

3688Smoot, D. T., 350Snider, Theron G., III, 1Snippe, H., 187Snodgrass, Terri L., 1772Snoy, Phil, 4240So, Magdalene, 3250Sobel, Jack D., 1990, 4202Soderland, Carl, 478Sohnchen, Rolf, 4560Sojar, Hakimuddin T., 2369,

3570Sokol, Pamela A., 656Soll, David R., 1823Songer, J. Glenn, 4310Soni, Rohini, 3382Sonnesyn, Steven W., 4777Sory, Marie-Paule, 3129Soutschek, Erwin, 2182Spaccapelo, Roberta, 3769Spagnoli, Giulio C., 4105Spagnolo, N., 5225Spano, Furio, 2347Sparling, P. Frederick, 2906Specter, Steven, 2216Spengler, Michael D., 1667Spiegelhalder, Christiane,5315

Spielman, Andrew, 2396Spik, Genevieve, 2694Spinola, Stanley M., 1346Splitter, Gary A., 5339Spratt, Brian G., 4382Springer, Timothy A., 2919Sreenivasan, Prem K., 1239Srikantha, Thyagarajan, 1823Srikumar, Ramakrishnan, 3334Sriwanthana, Busarawan, 2570Stabel, Thomas J., 610Stamm, Walter E., 213Standing, Joseph E., 4302Stanley, Samuel L., Jr., 520Stauffer, F., 1996Steele, Richard H., 2289Steere, Allen C., 2774Stein, Barry, 2357Stein, Daniel C., 3360Steiner, B. M., 1232Steiner, Donna A., 633, 2985Steinman, R. M., 5326

Stendahl, Olle, 1406Stephens, L. Clifton, 1268Stephens, Richard S., 2273,

3078Stevenhagen, Annelies, 3111Stevens, Daniel P., 1040Stevens, Dennis, 1194Stevens, Roy H., 3544Stewart, Scott J., 4093St. Geme, Joseph W. , III,

650, 2233Stiles, Bradley G., 5333Stinson, Murray W., 3259Stiver, H. Grant, 1829Stocker, Bruce A. D., 1211Stogsdill, Preston L., 876Stok, W., 303Stoker, N. G., 2145Storm, Paul K., 800Stover, C. Kendall, 1674Straley, Susan C., 3105Straus, David C., 253, 4669Street, Nancy E., 1146Stringer, James R., 4801Stringer, Saundra L., 4801Strugnell, R. A., 5374Strugnell, Tod, 1829Stuber, D., 268Stull, Terrence L., 4033Sturrock, Robert F., 4984Stutz, Peter L., 2015, 3518Su, C. J., 816Su, Hua, 4406Suarez, Carlos E., 3511Subbarao, Shambhavi, 4599Suchland, Robert J., 213Suga, Moritaka, 1980, 3552Sugimoto, Nakaba, 3611Sugimura, Kazuhisa, 329Sullivan, Patrick J., 3240Sumner, John W., 3536Sundan, Anders, 1917Sundstrom, J. B., 1340Supersac, G., 580Surcel, H. M., 2196Sutcliffe, Iain C., 1121Sutherland, Claire L., 1442Suto, Tsunehisa, 4350Suzuki, Kumiko, 289Suzuki, Yasuhiro, 2284Svanborg, Catharina, 602Svennerholm, Ann-Mari, 5190Svenson, Stefan B., 2289,5214

Swamy, Raji, 4501Swarts, J. Douglas, 1950Swierzko, Anna, 3216Switalski, Lech M., 4119Swoboda, Bernd, 2513Swoboda, R. K., 4263Syme, Rachel M., 464Sypek, Joseph P., 3901Sypherd, Paul S., 3648Syrjala, H., 2196Syuto, Bunei, 5309Szaniszlo, Paul J., 2069Szczepanski, Andrew, 5097

Tabaqchali, S., 2419Tabuni, Abdulmoneim, 4891Tacchini-Cottier, Fabienne,

4182Tacket, Carol O., 729

Tagawa, Yuichi, 91, 1750,2257, 4153

Taha, Muhamed-Kheir, 4662Tai, Hideaki, 3533Tai, Stanley S., 5401Takada, Haruhiko, 5252Takahashi, Ichiro, 1301Takahashi, Kazuko, 5044Takahashi, Yukihiro, 5181Takamoto, Y., 2270Takasawa, Toshihide, 5181Takayama, Kuni, 2296Takeda, Shugo, 551, 1853Takeda, Tae, 289, 764Takeda, Yoshifumi, 289Takenaka, Ichiro, 699Takeshita, Akira, 5219Takikawa, Osamu, 1810Talkington, Deborah F., 3369Tam, Susan H., 512Tambourgi, Denise V., 3656Tamura, Masato, 5252Tamura, Toshihide, 64Tanabe, Taishi, 2973Tanaka, Hiroshi, 3711Tanaka, Kenji, 3164Tanaka, Shoji, 5219Tandon, Narendra N., 2229Tang, Christoph M., 1650Taniguchi, Hatsumi, 1972Tannock, Gerald W., 3199Tantimavanich, Srisurang,

4005Tao, Lin, 1121Tarkkanen, Jussi, 3012Tarkowski, A., 3879Tart, Rebecca Creech, 4994Tartera, Carmen, 3084Tasaka, Hiromichi, 1173Tateda, Kazuhiro, 2468Taubman, Martin A., 2899Tavares, Delfina, 1881Taylor, David N., 3678Taylor, F. B., Jr., 4293, 5035Taylor, G., 2848Taylor, G. W., 2419Taylor, N. S., 2309Teale, Judy M., 2596Teeling, Peter, 1835Teixeira, Henrique C., 2154Telford, Sam R., III, 2396Telle, W. Brian, 1889ten Berg, Rob, 2687Terry, Simon D., 3199Terwilliger, Gordon A., 1814Tesh, Vernon L., 3392Teti, A., 5225Teti, Giuseppe, 227Tetzlaff, Christine L., 236Tew, John G., 2400Tham, Kyi T., 5008Thardin, J. F., 1432Theander, T. G., 268Theander, Thor G., 1069Theisen, Michael, 1793Theiss, Patty M., 2224, 3327,

5123Thelestam, Monica, 3988Theodos, Cynthia M., 5205Theus, Sue A., 4703Thisyakorn, U., 1149Thole, Jelle E. R., 3642

Thomas, D. Denee, 423, 3590,3892

Thomas, Warren, 1136Thompson, J. K., 2145Thompson, Robert C., 3342Thompson, Stuart A., 2906Thompson, Walter, 4240Thong, Y. H., 559, 4338Thornton, Julian C., 3854,

4582Tilley, Michael, 2377Tilney, Lewis G., 1486Timmerman, C. P., 4167Timmis, Kenneth N., 573Timoney, Peter J., 861Tine, John A., 3933Tinsley, Colin R., 3703Titball, Richard W., 3958Titus, Richard G., 5205Tobias, Peter S., 378, 1033Todd, James K., 3369Todd, Jeanne, 1682Todome, Yuko, 5252Todryk, Stephen, 4590Toews, Galen B., 3966Toffaletti, Dena L., 4446Toivanen, Paavo, 2498, 5261Tokue, Akihiko, 1307Tolle, Ralf, 40, 3490Tolmasky, Marcelo E., 3228Tomai, Mark A., 785Tomas, Juan M., 852Tomasello, Francesco, 227Tomicic, Tanja K., 3282Tomita, Mamoru, 719Tommassen, Jan, 4724Tompkins, Lucy S., 1764T0njum, Tone, 1909Tonnetti, Laura, 3769Townsend, Evelyn L., 2618Trabulsi, L. R., 1152Trees, David L., 4599Tremaine, Mary T., 356Treseler, Catherine, 4891Trinel, Pierre Andre, 1164,

4398Tripp, Cynthia A., 236Trofa, Andrew C., 3678Trout, Rodney, 391Troutt, Anthony B., 3459Tsai, Chao-Ming, 1873Tsang, K. W. T., 2848Tseng, Jeenan, 391Tsukada, Hiroki, 1334Tucci, Michelle, 3375Tufano, Maria A., 155Tummuru, Murali K. R., 1799Tuomanen, Elaine, 1538Tuomanen, Elaine I., 2780Tuosto, Loretta, 439Turco, Jenifer, 2383, 3412,

4317Turco, Salvatore J., 5205Turner, S. J., 5374Tylewska-Wierzbanowska,

Stanislawa K., 4188

Uchiyama, Takehiko, 3922,5252

Udhayakumar,Venkatachalam, 2425

Uggla, Arvid, 2639Uhl, Elizabeth W., 2985

INFECT. IMMUN.

AUTHOR INDEX xi

Uhlig, Katrin, 1185, 4870Ulevitch, Richard J., 378Ulrich, Robert G., 5333Ulrich, Terry, 5062Ulstrup, Jan C., 1730Umemoto, Toshio, 5219Unanue, Emil R., 3123, 5090Unbehagen, P. J., 253Upton, Steve J., 2377Urban, Britta, 1636Urbani, Francesca, 4105Uzzau, S., 1786

Vacheron, Marie-Jeanne, 5417Valentin, Alexis, 734Valmori, Danila, 3064Valone, S. E., 705van Ackern, Klaus, 3143Van Alphen, Loek, 4575Vandaele, J., 1432Vandekerckhove, Filip, 898van den Barselaar, Maria T.,

3038van den Bosch, Johannes F.,

800Van den Brink, M. E., 303Van Den Broek, Maries F.,

1936van der Biezen, Jenny, 4217Van der Heijden, P. J., 303van der Hulst, Marielle E. B.,

868van de Rijn, I., 4994van der Ley, Peter, 4217, 4724VanderVegt, F. Pierre, 5174van der Zeijst, Bernard A.

M., 5013van Doornik, Claudia E. M.,

5013Van Dyke, Thomas E., 3137van Embden, Jan D. A., 868van Furth, Ralph, 868, 3038,

3111Van Gaans, J. A. M., 187van Heeckeren, Anna M.,

4333Van Noorden, Susan, 1650Vanooteghem, Jean-Claude,

71Vanopdenbosch, Emmanuel,

4440Vanprapar, N., 1149Van Rooijen, Nico, 1936, 3244Van Strijp, J. A. G., 4167Van Tassell, Roger L., 2912Van Vooren, Jean-Paul, 2687Vargas, Sergio L., 619Vaughan, Laurence M., 2172Vavrin, Zdenek, 491Vazeux, Gilles, 4469Vazquez, Mary E., 1950Vecht, Uri, 3318Vega, Adaymee, 391Vega-L6pez, F., 2145Veit, Hugo P., 1682Vella, Anthony T., 5381Venzon, David, 1185, 4870Verbrugh, H. A., 4167Verdon, Renaud, 1687Verhave, Jan Peter, 1936Verheul, A. F. M., 187Verhoef, J., 187, 4167Verhoef, Jan, 3976

Vermeulen, Arno N., 4504Vervelde, Lonneke, 4504Vesin, Christian, 4182Viboud, Gloria Ines, 5190Vieth, Michael, 4008Villacorta, Isabel, 4440Villarreal-Ramos, Bernardo,

3981Virkola, Ritva, 4480Vivanco, Fernando, 852Voelker, LeRoy L., 2670Vogel, Liesbeth, 3334Vogel, R., 1453Vogel, Stefanie N., 2015,

2325, 3518Vogel, Ulrich, 2585von Hunolstein, Christina,

1272Vordermeier, Martin, 260Vorys, Ann, 3901Vreden, Stephen G. S., 1936

Waag, D. M., 1251Wacharotayankun,

Rochaporn, 3164Wachsmann, Dominique, 1082Wachsmuth, I. Kaye, 1619,

2220Wadolkowski, Elizabeth A.,

3392Wadsworth, Elsa, 4675Wagner, Barbara, 1272Wagner, Manfred, 1272Wagner, R. Doug, 3739Wahlgren, Mats, 284Waine, G. J., 4716Walev, Iwan, 4972Walker, I. D., 903Walker, K. Barry, 4501Walker, Mark J., 573Walker, T. Stuart, 2024Wall, Robert A., 751Wallich, Reinhard, 4158Wallis, Robert S., 627Walsh, Thomas J., 1185, 4870Walzer, Peter D., 4703Wang, Bo, 785Wang, Erica, 3482Wang, Haini, 3544Wannemuehler, Michael J.,

610Wanner, Gerd, 2182Warakomski, Don J., 81Warbington, Martha L., 3137Ward, G. E., 5237Ward, Joel I., 5345Warren, Jeffrey S., 1474Warren, John W., 2748, 3422Wasfy, Gihane, 2474Washburn, Leigh Rice, 2670Washington, Otis R., 1040Wass, Carol A., 975Wasserman, Glenn M., 1958Wasserman, Steven S., 729,3994

Watanabe, Naohiro, 2242Watkins, Johanna, 399, 3190Watson, Douglas C., 1023Watson, James D., 1509Watson, Wendy, 3375Wehland, Jurgen, 2793, 3073Weinstock, Christof, 5140Weinstock, George M., 3942

Weintraub, Andrej, 1211Weir, Susan, 1909Weis, Janis J., 3843Weisel, Heather R., 4392Weiser, Weishui Y., 338Weiss, Alison Ann, 807Weiss, Douglas J., 2618Welker, Yves, 1596Wellems, T. E., 3574Wells, Lance, 1900Weraarchakul, Witoon, 1567Wessels, Michael R., 2866,

4760West, Robert, 4017Westrack, Gary J., 81Wetzler, Lee M., 4734Wexler, Donald L., 1259Wheat, L. Joseph, 4607Whiley, R. A., 3076Whiteley, Laurence O., 2618Whithear, K. G., 903Whitlock, Joan, 940Whitmire, William M., 1460Whitney, Anne M., 1559Whittam, Thomas S., 204,

1619Wiater, Lawrence A., 5361Wick, Mary Jo, 4848Wickersham, Elizabeth A.,

3942Widders, Phillip R., 2558Widders, P. R., 2995Widen, Raymond H., 4027Wiedermann, U., 3952Wieles, Brigitte, 3642Wiertz, E. J. H., 187Wiest, Peter M., 4888Wigzell, Hans, 5129Wilde, Charles E., III, 1315Wilensky, S., 1453Wilkins, Tracy D., 2912Wilkinson, Brian J., 1567Wilks, M., 2419Will, Antje, 4008Will, Gitta, 2182Willems, Hemmie M. C., 800Willemsen, P. T. J., 4518Willett, Norman P., 5388Willgohs, JoAnn A., 2304Williams, Diana L., 1509Williams, D. M., 3556Williams, J. C., 1251Williams, Lori J., 777Williams, Neil M., 861Williams, Peter H., 760Williams, P. H., 4885Williams, Philip A., 2334Williamson, Diane, 3673Willson, Philip J., 565Wilske, Bettina, 2182, 2192Wilson, K., 2848Wilson, Michael A., 4360Wilson, R., 2419Wilson, Richard A., 1619Winegar, Robert K., 823Winkler, Herbert H., 2383,

3412, 4317Winner, L. S., III, 5279Winter, Ruth E., 5401Winters, Bradford D., 3259Wise, Kim S., 2224, 3327,

5123Wisniewski, Mark A., 3873

Wolfe, Marie L., 1619Wolf-Watz, Hans, 71, 2434Won, Jonghwa, 2813Wong, Christopher Y. F., 371Wong, Sin-Yew, 2284Wood, Steve, 3068Woods, Donald E., 4045Woods, Keith M., 4013Woods, Marion L., 491Woods, Vivienne M., 236, 3273Wozniak, Daniel J., 4208Wright, Esther L., 5286Wright, Rachel J., 3240Wu, Hong-Yin, 314Wu, Xu, 1829Wu-Hsieh, Betty A., 1468Wullenweber, Michael, 2138Wuorela, Maarit, 5261Wyler, David J., 3901, 3985

Xia, Dongyuan, 348Xie, H., 2260Xu, Yuhui, 1288Xu-Amano, Jiangchun, 4272

Yacoob, Reza, 2316Yamada, Satoru, 332Yamada, Takeshi, 1173, 4005Yamaguchi, Keizo, 2468Yamaguchi, Ryuji, 1173Yamamoto, Ayako, 3294Yamamoto, Chiyuki, 1972Yamamoto, Koshi, 329Yamamoto, Masashi, 5388Yamamoto, Nobuto, 5388Yamamoto, Shigeki, 2154Yamamoto, Yoshimasa, 2216Yamamoto, Yoshio, 5219Yamamura, Masahiro, 3482Yamashiro, Tetsu, 5398Yamashita, Y., 3811Yamauchi, Koji, 719Yamauchi, Lucy M., 4196Yamazaki, Akihiro, 1173Yan, Yingzhuo, 1040Yanagawa, R., 2270Yang, Czau-Siung, 1563, 4689Yang, Huiming, 656Yang, Ji, 2841Yang, W., 4716Yang, Yan-Ping, 2653Yang, Youxu, 3907Yang, Zi-Ping, 2037Yazdanbakhsh, Maria, 2827Yee, Arlene J., 4510Yeung, Maria K., 109Yi, Yajun, 1117Yikang, Deng, 1126Yin, Yibing, 2780Yip, Julie K. K., 3544Yogev, David, 2224Yokochi, Takashi, 5044Yokoo, Yutaka, 289Yokota, Masataka, 4147Yoneda, Toshiyuki, 3562Yoo, Han S., 2618Yoshida, Kazuko, 3552Yoshida, Nobuko, 3636, 4196Yoshida, Ryotaro, 1810Yoshida, Shin-Ichi, 699, 1972Yoshihara, Ryosuke, 3117Yoshikawa, Hiroko, 1334Yoshimura, Fuminobu, 5181Young, Bryan J., 2966, 4360

VOL. 61, 1993

xii AUTHOR INDEX INFECr. IMMUN.

Young, Douglas, 260Young, JoAnn, 1352Yu, Chang-En, 3719Yu, Xiaohui, 4622Yuasa, Noboru, 91, 1750,

2257, 4153Yuri, Kazuyo, 2270

Zarabi, Mehdi, 4743

Zealey, Gavin, 2316Zenner, Lionel, 360Zhan, Yifan, 2841, 4899Zhang, Min-Ying, 4947Zhang, Ya, 3351Zhang, Yue-Hua, 5044Zhang, Yu-Ying, 520Zhao, Qixun, 3078

Zhao, Shumin, 236Zhe, Huang Xiao, 289Zhong, Guangming, 1117Zhou, Jin, 3149Zhu, Yingxun, 5339Ziegelbauer, Karl, 4540Zimmerman, Peter, 2357Zimmermann, Charles R., 3090

Zimmermann, Sonja, 2138Zlotnick, Gary W., 1950Zlotnik, Albert, 4937Zoon, Kathryn C., 3222Zueco, Jesus, 3313Zulty, Joseph C., 2748, 3422Zwilling, Bruce S., 4793Zychlinsky, Arturo, 4064

SUBJECT INDEX

VOLUME 61

N-AcetylglucosamineS. mutans carbohydrate fermentation,

295S. sobrinus carbohydrate fermentation,

295Acid phosphatase

C. bumetii, 4232Acid resistance

enteric bacteria, 364Acid tolerance response genes

S. typhimunum virulence, 4489ActA polypeptide

L. monocytogenes, 2793localization, 2793

Actinaccretion

calcium-calmodulin dependence, 760HEp-2 cells

E. coli, 760lethality, 760

L. ivanoviicell-to-cell spread, 162

polymerizationdirectional, 1926

rainbow troutADP-ribosylation, 5392

rickettsiaespotted fever group, 1926

segmented filamentous bacteriaattachment sites, 4001

Actinobacillus actinomycetemcomitansadherence

extracellular components, 4933epithelial cell invasion, 1239fimbria antigen

immunoglobulin G, 332invasion

epithelial cells, 1239leukotoxin

cell surface nucleic acids, 4878plasmids

conjugal transfer, 3544incompatibility groups P and Q, 3544

serotype bimmunoglobulins reactive with immuno-

dominant antigen, 2400Actinobacillus pleuropneumoniae

ApxI operon, 3688ApxIII gene, 947outer membrane lipoprotein OmlA, 565vaccines

noncapsulated mutants, 1682Actinomyces

S. gordoniiSspA gene, 3199

Actinomyces naeslundiiS. gordonii coaggregation adhesin gene,

981Actinomyces spp.

oral, 2011P. intermedia

coaggregation, 2011Actinomyces viscosus

sialidase geneconserved repeating sequence, 109

ADE2 geneC. neoformans

cerebrospinal fluid, 4446Adenylate cyclase-hemolysin

apoptosis in macrophages, 4064B. bronchiseptica, 4072

B. pertussis, 4064CyaC-mediated activation, 3583

AdherenceA. actinomycetemcomitans

extracellular components, 4933B. burgdorferi extracellular vesicles,

3892C. albicans

keratinocytes, 4560yeast cells, 3244

H. pylongastric epithelial cells, 350gastrointestinal cells, 4051

Haemophilus genospeciesneonatal, 4112

P. aeruginosainhibition, 4338

P. multocida, 4785S. typhi, 3084

AdhesinsCampylobacter spp., 3440E. coli

afimbrial, 5106gene cluster, 2505nonfimbrial adhesin I, 2505P, 4902uropathogen, 2505

E. histolytica galactose, 1772fibronectin, 1889H. pyloni, 2474lipid binding, 2474mycobacterial, 1889P1, 1547S. defectivus, 4994S. mutans, 1547S. parasanguis, 1016

AdhesionB. piliformis, 876C. albicans

polymethylmethacrylate, 2644salivary mucin, 1940

E. coliattaching-effacing, 448

H. pylon, 448gastric epithelial cells, 4058

P. falciparum-infected erythrocytesCD36, 2229

S. mutansdentin, 4119

S. mutans cell surface antigen I/IIprotein fragment, 4590

S. typhimunum, 5013T. cruzi, 3636Y enterocolitica

mucin, 2340AdjuvantsN. meningitidis oligosaccharide-protein

conjugates, 187ADP-ribosylationbotulinum C2 toxin, 5392rainbow trout actin, 5392

ADP-ribosyltransferase C3C. botulinum type D

lysogenized, 5309Adult respiratory distress syndrome

interleukin-8, 4553Aeromonas hydrophila

outer membrane proteinscarbohydrate reactive, 371

xiii

Aeromonas salmonicidaantigens

novel, 4582aromatic-dependent mutant

vaccine, 2172in vivo, 3854

afa-3 gene clustersafimbrial adhesins, 5106E. coli, 5106

agrS. aureusmurine arthritis model, 3879virulence, 3879

sea expression, 356ail geneY enterocolitica, 1846

Albuminmacrophages

inflammation-primed activation, 5388Alginate

immunosuppression, 559P. aeruginosa, 559

Alkaline phosphataseoral vaccine carrier, 48

Alkaline proteasesA. fumigatus, 1650

Alpha-2-macroglobulinproteinase inhibitor in sepsisbaboon model, 5035

a-AntigenB-cell epitopes, 1173M. avium, 1173

a-Antigen geneM. avium, 1173

Alpha-toxinC. novyi, 2912C. perfringens, 3711keratinocyte killing, 4972phosphatidic acid, 3711S. aureus, 4972

Alpha-toxin genesC. perfringens types A and C, 457transcription regulation

extragenic, 457Aminopeptidases

streptococcimutans group, 182

Anaplasma marginaleMSP4 outer membrane protein, 5245

AngRanguibactin hyperproduction, 3228V. anguillarum, 3228

Anguibactinhyperproduction, 3228

Anthrax lethal toxinmacrophages

resistance, 245sensitivity, 245

Antibacterial polypeptidesE. coli binding, 966neutrophils, 966

Antibioticsmonoclonal antibody HA-1A

binding to smooth gram-negative bac-teria, 512

AntibodiesB. bacilliformis, 4962B. duttonii, 4147C. parvum, 4079flagellin, 4962H. influenzae type b capsular polysac-

xiv SUBJECT INDEX

charide, 5345H. somnus

bovine uterus, 2558N. meningitidis, 187P. falciparum, 4498

p82 rhoptry protein, 2960S. minnesota lipopolysaccharide, 3216salivary, 3597

Antigen 85 complexM. leprae, 1835

Antigen 85 complex gene familyM. leprae, 3642

Antigen complexM. bovis BCG, 742

Antigenic stabilityB. burgdorferi, 4955

Antigenic variationM. fermentans, 5123minireview, 2273

Antigen-presenting cellsstreptococcal M protein, 785T-cell activation, 785

AntigensA. fumigatus, 4767A. salmonicida, 4582C. albicans, 4398

cell wall, 4842gpl90, 32H. pyloni, 1799L. (L.) anazonensis amastogotes, 2131M. hyorhinis, 2224M. leprae, 2145mycobacteria, 1509P. carinii, 1315P. falciparum

protective, 892P. gingivalis, 3294S. mutans, 1301

surface protein antigen saliva-bindingregion, 4344

T. cruzi, 4196T. denticola, 1694T. gondiiimmune responses, 2639iscoms, 2639

T. gondii bradyzoitesIFN-y-treated macrophages, 1141

U. urealyticum, 2253V. anguillarumchromosomal virulence locus, 2434flagellar sheath, 2434

Y enterocoliticaarthritogenic cationic 19 kDa, 2498

Anti-idiotype antibodiespyelonephritis

primate model, 2289Antimicrobial proteinsmacrophages

murine, 3038Aotus monkeys

P. falciparumrecombinant SERA protein, 2041,

2048Apolipoprotein A-Imonokine release

endotoxin induced, 5140prevention, 5140

Apoptosislipopolysaccharide, 5044thymus, 5044

apr geneP. aeruginosa LasR, 1180

ApxI operonA. pleuropneumoniae, 3688

ApxIII geneA. pleuropneumoniae, 947

Arcanobacterium haemolyticumphospholipase D

C. pseudotuberculosis phospholipaseD, 4310

Arcobacter butzleridiarrheal illness

primates, 2220Arginine deiminaseMycoplasma species

gene polymorphism, 329Arthritis

adjuvantmodulation by vaccinia virus express-

ing hsp6o, 4225peptidoglycan-polysaccharide polymers

cell walls, 4645reactivation, 4645

Arthrobacter straindextranase

S. gordonii, 4375Asialo GM1

corneal glycolipid receptor, 5164P. aeruginosa adhesion, 5164

Aspartyl proteinaseC. albicans, 2030

Aspergillosiselastolytic serine protease, 2357

Aspergillus fumigatusacquired immunity, 3791alkaline protease, 1650antigen

88 kDa, 4767secreted, 4767

granulocyte colony-stimulating factor,1185, 4870

IFN--y, 1185, 4870metalloprotease

secreted, 4099neutrophils, 1185polymorphonuclear leukocyte-induced

damagecorticosteroid-induced suppression,

4870Aspirin

endocarditisaortic valve, 1593

low dose, 1593ATPase inhibitorsH. pylori vacuolating toxinHeLa cell response, 1427

Attaching and effacing locusC. freundii, 2486

AttachmentM. arthritidis, 2670

B cellsB. burgdorfenimembrane blebs, 1460

P. mirabilis OmpAmitogen, 4915

T-cell subsetsleishmaniasis, 2266TH1, 2266TH2, 2266

Babesia bovisBb-1 proteinThl cell epitopes, 236

CD4+ T cell clones

cytokine profiles, 3273rhoptry-associated protein 1

B-cell epitopes, 3511Babesia divergens

exoantigensculture derived, 734vaccination, 734

vaccinationexoantigens, 734

Baboonscomplement system

activation, 4293E. coli, 4293

Bacillus piliformisadhesion, 876invasion, 876

Bacillus thuningiensisflagellin, 4947phospholipases, 4947pleiotropic mutant

avirulent, 4947Bactenecins

spirochetes, 3081Bacterial clearance

endotoxin, 3143tumor necrosis factor, 3143

Bacteroides fragilisneuraminidase, 4415

Bartonella bacilliformisantiflagellin antibodies, 4962erythrocyte invasion, 4962flagella, 4962

B-cell epitopesB. bovis rhoptry-associated protein 1,

3511C. trachomatis heat shock protein 60,

1117H. influenzae type b P1-specific mono-

clonal antibodies, 1867M. leprae 70-kDa heat shock protein

variable C-terminal region, 135P. falciparum circumsporozoite protein

antibody responses, 2425pertussis toxinS4 subunit, 2408

32 microglobulin-deficient miceL. monocytogenes, 1113

Beta-toxinC. perfringens, 3958

BindingP. cepacia, 3157tumor necrosis factor alpha, 830

Bone resorptionfibroblast-activating factor, 3562P. gingivalis, 3562

Bordetella bronchisepticaadenylate cyclase-hemolysin, 4072dermonecrotic toxin

stimulation of DNA synthesis, 3611lactoferrin, 2698siderophore production mutant, 2698

Bordetella parapertussisB. pertussis

immunologically distinct, 486Bordetella pertussis

adenylate cyclase-hemolysinCyaC-mediated activation, 3583

apoptosis in macrophagesadenylate cyclase-hemolysin, 4064

B. parapertussisimmunologically distinct, 486

cell-mediated immunity, 399, 3190environmental regulators, 807

INFEcr. IMMUN.

SUBJECT INDEX xv

filamentous hemagglutinincarbohydrate recognition domain, 2780long-lived respiratory immune re-

sponse, 1447immunization, 3190pertactin, 2211Thl cells

bacterial clearance, 399vaccine

hemagglutinin and pertussis toxoid,573

liposomes, 573Borrelia burgdorferi

antigenic stability, 4955arthritis

treatment resistant, 2774B cells, 1460CS

deficiency, 2104cell-mediated immune responses, 1814complement-dependent killingimmunoglobulin G Fab fragments,

2532cytadherence

inhibition, 423dissemination

fulminating infection, 2396rapid, 2396

fulminating infectionrapid dissemination, 2396

HLA-DR4, 2774intradermal inoculation sites

variant responses, 4493lipoprotein

polymorphic, 4158membrane blebs, 1460monoclonal antibodies39-kDa protein, 4523

OspAimmunogenicity, 81lipid attachment, 81monoclonal antibody, 423

OspA and OspBantibody reactivity, 2774

OspA and OspB lipoproteinsB-cell mitogenic and cytokine-stimula-

tory properties, 3843OspA vaccination, 2553OspA- OspB- mutant

protective immunity, 5115OspB mutant, 3590OspC, 5097

circular plasmid, 2192cryptic, 2192polymorphisms, 2182

outer surface proteinsregulation of expression, 2207

p23North American strain, 5097

protein39 kDa, 4523monoclonal antibodies, 4523

seroprotective groups, 4367serum passive immunizing activity, 4696vaccinationOspA, 2553

vesiclesadherence, 3892extracellular, 3892

Borrelia duttoniiantibody transfer, 4147

Botulinum C2 toxinADP-ribosylation, 5392rainbow trout actin, 5392

Brefeldin Aheat-labile enterotoxins

cholera, 3282E. coli, 3282inhibition, 3282

Brucella abortuscytokines, 2841

effects on intracellular growth, 124IFN-y, 4899intracellular growth

effects of cytokines, 124lipopolysaccharide

T-cell-independent type 1 carrier, 1722omp2, 3785porins, 3785proteins

cytokine response of T-cell subsets,2841

ssb, 5339uvrA, 5339

Brugia malayieosinophils, 5410major histocompatibility complex class

II molecules, 5410T-helper-cell responses, 1105

ClqK pneumoniae outer membrane proteins

binding, 852L. monocytogenes

phagocytosis, 3664C3

binding, 5134C. albicans, 1779C. neoformans, 2966C. trachomatis

binding, 1829granulocyte-macrophage colony-stimulat-

ing factor, 1779H. influenzae outer membrane protein

binding sites, 5157L. monocytogenes, 5134monocytes, 1779

C3bC. neoformans capsulebound, 4360

decay to iC3baccelerated, 4360

Y enterocoliticaopsonization, 3129YadA, 3129

C3dC. albicans recognition, 2662

CSB. burgdorferi, 2104endotoxic shock, 1474tumor necrosis factor, 1474

CSaCSa-ase, 1421streptococcigroup B, 1421

CSa-asestreptococcigroup B, 1421

C57BLI6 miceY enterocolitica, 2585

C57BL/10 micecytokine levels, 2952L. amazonensis, 2952

cagA geneH. pylon, 1799

CalciumC. trachomatis intracellular aggregation,

1406Campylobacter jejuni

cyclic AMP, 4885flagella

adherence, 1764internalization, 1764translocation, 1764

flagellar biogenesis, 2930LcrD/FlbF homolog, 2930leukotriene B4, 4885lipopolysaccharide

O-polysaccharide chains, 5384model

primary swine intestinal cells, 2723piglet model, 3466prostaglandin E2, 4885

Campylobacter spp.adhesins, 3440

Candida albicansadherence

keratinocytes, 4560lymph node tissue, 3244

adhesionpolymethylmethacrylate, 2644salivary mucin, 1940submandibular-sublingual saliva, 2644

antigenscell wall, 4842immunoglobulin G3 epitopes, 1164phospholipomannan, 4398

aspartyl proteinase, 2030avirulent clones, 2662C3, 1779C3d recognition, 2662carbohydrate supplementation, 619CB-17 mice, 3530CD4+ subset differentiation, 3769cell elongation, 3648cell wall antigensmonoclonal antibodies, 4842

cell-mediated immunity, 1990colonization and invasion modulation

dietary carbohydrate supplementation,619

colony-stimulating factorgranulocyte-macrophage, 1779

cytokine gene expressionperipheral blood mononuclear cells,

4105ECE1, 3648gastrointestinal

scid mice, 2520glycolytic enzymesimmunogens, 4263

hematogenous candidiasisspecies differences in pathogenicity,

1268iC3b receptor, 1395immunoglobulin G3 epitopes

13(1-2)-linked oligomannosides, 1164interferon

poly(I- C) induced, 3530intracerebral infection, 3476intraperitoneal administration, 2520lipopolysaccharide, 2216mannan

delayed hypersensitivity, 2122monophosphoryl lipid A, 2122

mannans

VOL. 61, 1993

xvi SUBJECT INDEX

adherence of yeast forms, 2578mannoproteins

anti-complement receptor type 2 anti-bodies, 4675

blastoconidia, 4675hyphae, 4675

monoclonal antibodiescell wall antigens, 4842

natural killer cell activityabrogation, 2520

natural killer cells, 3769nongerminative variant

elevated vaginopathic potential, 1500filamentous growth, 1500low systemic virulence, 1500

oligomannosides3(1-2) linked, 1164

opaque-phase-specific genescoordinate regulation, 1823

peripheral blood mononuclear cellscytokine gene expression, 4105mannoprotein stimulation, 4105

phospholipomannan antigen, 4398polymorphonuclear neutrophils

retrovirus-immunosuppressed mice,2216

proteinimmunological activities, 1881

secreted aspartyl proteinase genes, 3240surface antigen mutants, 3449T-cell line

protection, 3540Thl-type responsesCandida specific, 4202

vaginal, 1990, 4202yeast cell adherencelymph node tissue, 3244

Candida factor 1 and 9 antiseraepitopes recognized, 3313S. cerevisiae mnn mutants, 3313

Candida kruseihematogenous candidiasis

species differences in pathogenicity,1268

Candidiasishematogenous

species differences in pathogenicity,1268

CapillariesN. asteroides

attachment, 955penetration, 955

Capsular polysaccharidestreptococcigroup B, 4835respiratory epithelial cell invasion,

4835Capsular polysaccharide biosynthesis de-

terminantsK pneumoniae, 4208

Capsular type polysaccharideS. agalactiae, 1272

CapsulesV. vulnificus

virulence, 1611Carageenanmice

lethality, 699platelet-activating factor antagonist, 699tumor necrosis factor, 699

Carbohydrate fermentationN-acetylglucosamine, 295S. mutans, 295

S. sobrinus, 295Carbohydrate supplementationC albicans

colonization, 619invasion, 619

dietary, 619CatalaseN. gonorrhoeae, 1232

Cathepsin Ghuman lysosomal, 1900P. aeruginosa, 1900synthetic, 1900

Cation fluxerythrocytes, 4326V. parahaemolyticus thermostable direct

hemolysin, 4326CB-17 mice

candidiasissystemic, 3530

CD4+ subset differentiationC. albicans-infected mice, 3769natural killer cells, 3769

CD4+ T cellsC. parvum, 3928dynamics, 1516host predisposition to infection, 1516

CD14endothelial cell injury and activation

endotoxin mediated, 3149soluble, 3149

CD36P. falciparum-infected erythrocytes

adhesion, 2229CDC genesW. dermatitidis, 2069

Cecropin P1E. coli, 2978mechanism of action, 2978

Cell wall polymersarthritis

reactivation, 4645peptidoglycan-polysaccharide, 4645

Cell-mediated immunityB. burgdorfen, 1814B. pertussis, 3190C. neofornans

cytokine profiles, 4750candidiasis

vaginal, 1990Chitinase/immunodiffusion-complement

fixation proteinC. immitis, 3090

Chlamydia pneumoniaecell-mediated immunitylymphocyte blast transformation, 2196

TWAR pneumonitismouse model, 2037

Chlamydia psittacimajor outer membrane protein gene

lack of allelic polymorphism, 3078Chlamydia trachomatis

F-actin, 1406aggregation

intracellular, 1406C3

binding, 1829calcium, 1406heat shock protein 60

B-cell epitopes, 1117IFN--y, 491, 3556major outer membrane protein

expression in E. coli, 4093major outer membrane protein gene

variable domains, 213major outer membrane protein neutrali-

zation epitopeexpression by poliovirus hybrid, 4406

monoclonal antibodyC-complex serovars, 1365neutralizing, 1365outer membrane protein variable do-

main I, 1365mouse pneumonitis biovarimmune response, 772intrauterine infection, 772

neutralizationantibody isotype, 498host cell type, 498

nitric oxide productionMcCoy cells, 491

Cholera toxinB subunit

female rat genital tract immune re-sponse, 2162

keyhole limpet hemocyanin, 2162N-terminal peptide addition, 384oral vaccine carrier, 48reduced immunogenicity, 384

binding, 5271brefeldin A, 3282chloride secretory response, 5271immunoglobulin A, 5279

monoclonal, 5271interleukin-6, 4637mucosal antibody response

impaired, 3952schistosomiasis mansoni, 4919vitamin A, 3952

Chylomicronsendotoxin excretion in bile, 3496

Citrobacterffreundiiattaching and effacing locus, 2486colonic hyperplasia, 2486cytotoxins

Shiga-like toxin II related, 534eae

transmissible murine colonic hyperpla-sia, 4654

Clonal relationshipsE. coli, 1619

Clostridium botulinumADP-ribosyltransferase C3

lysogenized organisms, 5309Clostridium difficile

toxin ACa2"-independent effects, 3988

toxin Bmonocyte and macrophage effects,

1082Clostridium novyi

alpha-toxin, 2912Clostridium.perfringens

alpha-toxin genesextragenic regulation of transcription,

457type A and C strains, 457

alpha-toxin-induced hemolysis, 3711beta-toxin, 3958enterotoxin gene, 3429iota-toxin genes, 5147phosphatidic acid, 3711

Coccidioides immitisantigen 2monoclonal antibody, 1895

chitinase/immunodiffusion-complementfixation protein, 3090

INFECT. IMMUN.

SUBJECT INDEX xvii

CollagenP. gingivalis protease, 2369S. mutans adhesion

dentin, 4119Colonic hyperplasia

C. freundii, 2486Colony-stimulating factors

C3, 1779C. albicans, 1779granulocyteA. fumigatus, 1185, 4870neutrophil apoptosis and ingestion,

1972neutrophils, 1185

granulocyte-macrophage, 1779coml outer membrane protein gene

C. bumetii, 470Complement

B. burgdorferi, 2532E. histolytica

trypsin-sensitive surface compo-nent(s), 1636

neutrophils, 3533P. gingivalis, 3533

Complement alternative pathwayL. monocytogenesC3 binding and proteolysis, 5134

Complement classical pathwayK pneumoniae outer membrane proteins

activation, 852Complement receptorsMac-1, 2919R. equi

binding, 2919Complement systembaboons

E. coli, 4293Corneal infection

P. aeruginosa, 2713CorticosteroidsA. fumigatus, 4870

Coxiella bumetiiacid phosphatase, 4232coml outer membrane protein gene, 470L929 cells, 4485reproductive system penetration, 4188

C-reactive proteinP. yoelii sporozoites, 348transgenic mice, 348

Cryptococcus neoformansADE2 gene, 4446binding

phagocytes, 4891C3

activation, 2966binding, 2966

C3baccelerated decay, 4360bound to capsule, 4360

cell-mediated immune responsecytokine profiles, 4750

cerebrospinal fluid, 4446delayed-type hypersensitivity

cellular infiltrates, 2854cytokine production, 2854

endothelial cells, 3818factor sera

specificity, 2879glucuronoxylomannan

tolerance mechanisms, 1340intracerebral infection, 3476lymphocyte proliferation, 464mannose-binding protein, 4891

neutrophilsmobility, 5067

phagocytes, 3818polysaccharide capsule, 464protective host response

primary lung infection site, 5302T cell independent, 5302

Cryptosporidiaoocyst protein

repeated amino acid motifs, 2347Cryptosporidium parvum

antibodiescolostral, 4079infectivity inhibition, 4079

antibody responses, 4440CD4+ cells, 3928endometrial carcinoma cell line, 1482halofuginone lactone, 4440IFN-y, 3548, 3928microtubule inhibitors, 4888monoclonal antibody, 4906SCID mice, 3548, 4906sporozoite proteins

shared epitopes, 2377Cyclic AMP

C. jejuni, 4885Cysteine-rich surface proteins

Giardia spp., 2937Cystic fibrosis

lactoferrinproteolytic cleavage, 5049

P. aeruginosa, 5049transferrin

proteolytic cleavage, 5049Cytidine 5'-monophospho-N-acetyl-

neuraminic acidN. gonorrhoeae

serum resistance, 1657Cytoadherence

P. falciparum, 5198CytoadhesinsM. hominis, 2945

Cytokine gene expressionC. albicans mannoprotein, 4105peripheral blood mononuclear cells, 4105

Cytokine inductionstreptococci

extracellular products, 5252oral, 5252viridans group, 5252

Cytokine mRNAcentral nervous systemSCID mice, 4038

T. gondii, 4038Cytokine mRNA expression

L. monocytogenes, 3739Cytokine production

lipopolysaccharide tolerance, 4356mycobacterium-reactive T-cell clones,

197T-cell clonesmycobacterium reactive, 197

Cytokine profilesB. bovis-specific CD4' T cell clones,

3273C. neoformans

cell-mediated immune response, 4750Cytokine releasepep M5, 1194peripheral blood mononuclear cells, 1194

Cytokinesanti-tumor necrosis factor alpha antibod-

ies, 227

B. abortusintracellular growth, 124

B. abortus proteins, 2841E. coli, 602epithelial cells, 602gene expression, 2545interleukin-6, 4637L. amazonensis, 2952L. monocytogenes, 2545P. falciparum cytoadherence, 5198release, 2545S. typhimurium porins, 155streptococcigroup B, 227

tuberculosis, 3482Y. enterocolitica, 2545

Cytolytic activityM. tuberculosis, 2708

Cytotoxic necrotizing factor 1 geneE. coli, 4909

CytotoxinsC. freundii, 535H. ducreyi

neutralizing antibodies, 1589Shiga-like toxin II related, 534

DehydroepiandrosteronePnu-Imune vaccine, 2238

Delayed hypersensitivityC. albicansmannan, 2122

monophosphoryl lipid A, 2122Delayed-type hypersensitivity

C. neoformans, 2854Dendritic cellsM. bovis BCG

antigen presentation, 5326Dental plaque bacteriaimmunoglobulin A

secretory, 3597Dentin

S. mutans adhesioncollagen, 4119

Dermonecrotic toxinB. bronchiseptica, 3611DNA synthesis stimulation, 3611

DextranaseArthrobacter strain

S. gordonii, 4375DiarrheaA. butzleni, 2220

Diphtheria toxinchannel-forming activities, 2200membrane translocation, 2200monoclonal antibodies, 994structure-function analyses, 994

Dirofilaria immitissuperoxide dismutase

immunolocalization, 1157Dissemination

B. buwgdorferi, 2396DnaK protein

E. rhusiopathiae, 411

eae geneC. freundii

transmissible murine colonic hyperpla-sia, 4654

eae sequencesE. coli

enteropathogenic, 2203

VOL. 61, 1993

xviii SUBJECT INDEX

eaeA gene productE. coli 0157:H7, 4085

ECEI geneC. albicans

cell elongation, 3648Echinococcus multilocularis

protoscolices, 525T cellsCD8+, 525suppression of proliferation, 525

Egg whitesE. coli P adhesins

inhibitors, 4902P1 antigen containing, 4902

Ehrlichia chaffeensisprotein

E. coli GroEL protein homolog, 3536immunoreactive, 3536

Ehrlichia risticiibinding, 3803flow cytometry, 3803interleukin-la, 4333interleukin-6, 4333internalization, 3803killing

peritoneal macrophages, 861peritoneal macrophages, 861proliferation, 3803prostaglandin E2, 4333tumor necrosis factor alpha, 4333

Eicosanoidsmacrophages

peritoneal, 1432phospholipases, 1432T. gondii

penetration, 1432Eikenella corrodens

pilin genessequence divergence, 1909

Eimeria tenellaepitopes

cecal epithelium of chickens, 4504sporozoites, 4504

sporozoitesepitopes, 4504

ElastasesP. aeruginosa, 1400, 2681paracellular permeability, 2681

eNAP-2serine proteases

selective inhibition, 2991Endocarditis

aortic valve, 1593aspirinlow dose, 1593

bacterial, 5413interleukin-6, 5413tumor necrosis factor alpha

receptors, 5413Endometrial carcinoma cell line

C. parvum, 1482Endothelial cell injury and activationCD14

soluble, 3149endotoxin mediated, 3149

Endothelial cellsC. neoformans, 3818phagocytes, 3818S. pneumoniae, 1538

Endotoxic shockC5, 1474tumor necrosis factor, 1474

Endotoxinsbacterial clearance

alterations, 3143blood

distribution, 3209chylomicrons

excretion in bile, 3496endothelial cell injury and activation,

3149glucocorticoids, 970hemoglobin

stroma-free, 3209Kdo disaccharide

synthetic analog binding, 3616lethality

D-galactosamine-sensitized mice, 970rough typeKdo disaccharide, 3616

tumor necrosis factor alphamurine embryo fibroblasts, 1630

Entamoeba histolyticaadhesin

galactose, 1772chromosomal patterns, 3574complement resistance, 1636electrophoretic karyotypes, 3574galactose adhesin

neutralizing monoclonal antibodyepitopes, 1772

myosin heavy chain A, 1048trypsin-sensitive surface component(s),

1636Enteric bacteria

acid resistance, 364Enterotoxin gene

C. perfringens, 3429Enterotoxins

heat stableY enterocolitica, 764

S. aureustype A internal deletion mutants, 2059

staphylococcalB, 391, 2445, 4937emetic and T-cell-stimulatory activi-

ties, 3175IL-10, 4937lipopolysaccharide-potentiated toxic-

ity, 5333novel type C, 4254

Y enterocolitica, 764Environmental regulators

B. pertussis, 807Eosinophils

B. malayi, 5410major histocompatibility complex class

II molecules, 5410epf and epf* genes

S. suis, 3318Epithelial cellsA. actinomycetemcomitans

invasion, 1239cytokine production, 602E. coli, 602interleukin-8, 4569P. gingivalis, 2260pneumolysin, 1352pulmonary alveolar

pneumolysin, 1352Epitopes

E. tenella sporozoitescecal epithelium of chickens, 4504

Erysipelothrix rhusiopathiaeDnaK protein, 411

ErythrocytesB. bacilliformis invasion, 4962cation flux, 4326CD36

binding, 2229P. falciparum, 2229P. falciparum-derived antigens, 284V. parahaemolyticus thermostable direct

hemolysin, 4326Erythrogenic toxin A

inflammatory mediator releaseneutrophils, 1055

S. pyogenes, 1055Escherichia coli

adhesinsafimbrial, 5106nonfimbrial adhesin I gene cluster,

2505P, 4902P1 antigen-containing avian egg

whites, 4902uropathogen, 2505

afa-3 gene clusters, 5106alpha-hemolysin vaccine, 1091antibacterial polypeptides

binding, 966neutrophils, 966

attaching-effacingadhesion, 448

attaching-effacing lesions, 1153attachment-effacement, 3382baboonscomplement system activation, 4293

clonal relationshipshemorrhagic colitis and infantile diar-

rhea, 1619coccoid

large intestine of streptomycin-treatedmice, 5029

colonization, 2138Col-, 1293enhanced, 1293

colonization factorfimbrial, 5190PCFO20, 5190

cytokinesepithelial cells, 602

cytotoxic necrotizing factor 1 gene, 4909diarrheagenic clones, 1619DNA sequenceenhanced colonizing ability, 1293stimulation of type 1 fimbria synthesis,

1293eae sequences, 2203eaeA gene product

serotype 0157:H7, 4085enteroaggregative, 1126enterohemorrhagic091:H21, 3832virulence, 3832

enteropathogenic, 2203HEp-2 cells, 760transepithelial electrical resistance,

2755enterotoxigenic, 2249, 3673, 5190epitopes

compartmentalization, 4848phagocytic processing, 4848

F165,-negative TnphoA mutantsepticemia, 836

fimbriaeaggregative adherence fimbria I

expression, 1126

INFECT. IMMUN.

SUBJECT INDEX xix

chickens, 800Fll, 800F1651-negative mutant, 836gangliosides, 2108glycosphingolipid, 3673interleukin-6, 3060intracellular adhesion molecule 1, 3060K88, 3673K88 receptors, 2526K99 binding to N-glycolyl-GM3 gangli-

oside receptor, 4518major histocompatibility complex class

II molecules, 3060mutation, 1667S, 544, 3060, 4480S specificity, 2108type 1, 1667type 1 synthesis stimulation, 1293virulence, 1667

heat shock proteinsantibodies in S. aureus endocarditis

patients, 1567heat-labile enterotoxins

brefeldin A, 3282heat-stable enterotoxins

guanylin superagonist, 4710immunization, 4629monoclonal antibodies, 289mucosal protection, 4629STh, 289

HeLa cells, 1153hemolysinT lymphocytes, 1715

HEp-2 cellsactin accretion, 760

immunized micetumor necrosis factor alpha, 3976

immunoglobulin Ganti-O-specific lipopolysaccharide, 975

invasiveness, 2138Kl

colonization, 2138invasiveness, 2138

K54 capsular polysaccharide genesdisruption, 3578TnphoA, 3578

lamininsialyloligosaccharide chains, 4480

lipopolysaccharidemonoclonal antibody, 3863

lipopolysaccharidesuroepithelial cells, 3304

major histocompatibility complexclass I and class II, 4848

meningitis isolate, 544mucosa

duodenal, 1153mucus

ileal, 2526K88 receptors, 2526

non-classic enteropathogenic serotypes,1153

nontoxinogenicinfantile diarrhea, 4894virulence determinants, 4894

"nonuropathogenic," 3422pap-, sfa-, and afa-related gene clusters

F165-positive bovine and porcine iso-lates, 2453

PCFO20, 5190peptides

cecropin P1, 2978intestinal, 2978

mechanisms of action, 2978PR-39, 2978

phagocytic killingneutrophils, 1442

987P pilus geneschromosomal, 2249plasmid, 2249

plasmidsconjugal transfer, 3544incompatibility groups P and Q, 3544

pyelonephritisoligosaccharide-protein conjugate vac-

cine, 5214prevention of renal scarring, 5214

S fimbrial adhesin II complex, 544S. sobrinus antigen fusions

heat-labile toxin B subunit, 1004serotypes

non-classic enteropathogenic, 1153Shiga-like toxinmitomycin, 4510

Shiga-like toxin IB-subunit expression and localization,

1098Shiga-like toxins type I and type II

relative toxicities, 3392superoxide dismutase, 1442tumor necrosis factor alpha, 3976urethral obstruction, 3422uroepithelial cells, 3304urosepsis, 4902vaccines

alpha-hemolysin, 1091verotoxin producing

attachment-effacement, 3382immunocompromise, 2304

Exfoliative toxinS. hyicus, 2973

Exoenzyme SP. aeruginosa, 307

Exopolysaccharidemucoid, 777P. aeruginosa biofilms, 777

ExotoxinsA, 2468domains lb and III, 5417LasR, 1180P. aeruginosa, 1180, 5417

P. aeruginosa, 1180septicemia, 2468

staphylococcalnatural killer cell cytotoxicity, 4013T-cell activation, 4013

F-actinC. trachomatis intracellular aggregation,

1406Factor sera

C. neoformans, 2879Fc receptor

neutrophils, 1415streptococci

type III group B, 1415Fibroblast-activating factorbone resorption, 3562P. gingivalis, 580, 596P. gingivalis derived, 3562

Fibroblastsfibroblast-activating factor

P. gingivalis, 596gingival, 596modulation

fibroblast-activating factor, 596Fibroblast-stimulating factor 1

S. mansoniegg granulomas, 3985

FibronectinM. bovis85B secreted protein, 4828

mycobacterial adhesin, 1889streptococcal phagocytosisenhancement, 2334group B, 2334

yersinia binding, 2513Filamentous hemagglutinin

B. pertussis, 1447, 2780carbohydrate recognition domain, 2780immune response

long lived respiratory, 1447Filariasis

gpl5/400 repeat subunitimmunoglobulin E, 2827primary structure, 2827

lymphatic, 2827Fimbriae

aggregative adherence, 1126E. coli, 2108, 3060, 4518

aggregative adherence fimbria Iexpression, 1126

chickens, 800enterotoxigenic, 3673Fll, 800glycosphingolipids, 3673K88, 3673K88 receptors, 2526meningitis isolate, 544virulence, 1667

K99N-glycolyl-GM3 ganglioside receptor,

4518P. gingivalis, 5181P. mirabilis, 884S, 2108, 3060S fimbrial adhesin II complex

E. coli, 544S. flexneri, 1687

FimbrillinP. gingivalis, 1040, 3570recombinant, 1040

FlagellaB. bacilliformis, 4962C. jejuni, 1764, 2930

FlagellinB. thunngiensis

avirulent pleiotropic mutant, 4947Flow cytometry

E. risticii, 3803Foreskin cellsH. ducreyi

adherence, 1735Francisella tularensis

IFN--y, 689immunity, 823M. bovis BCG-treated mice, 689nitrogen oxide synthesis, 689resistanceT cell independent, 823

tumor necrosis factor alpha, 689FrpA proteinN. meningitidis, 2906secretion

extracellular, 2906Fructosyltransferase operon fusion strains

S. mutans, 1259

VOL. 61, 1993

xx SUBJECT INDEX

ftf and gtfBC operon fusion strainsS. mutans, 1259

fur homologN. gonorrhoeae, 4599

Furunculosisvaccine, 2172

Fusobacterium nucleatumPRB3 null mutations, 4434saliva

interactions, 4434

Gamma-hemolysin locusS. aureus, 768

GastritisH. felis

active chronic, 2309immune responses, 2309

Giardia lambliamembrane proteins

zinc binding, 520TSA 417

antigenic switching, 5394trophozoite variable surface protein,

5394zinc binding

cysteine dependent, 520membrane proteins, 520

Giardia spp.cysteine-rich surface proteins

variant, 2937Gingival tissuesmonocyte chemoattractant protein 1,

4622Gl proline-rich glycoprotein

F. nucleatuminteractions with saliva, 4434

PRB3 null mutations, 4434Glia cellsN. asteroides, 343

Glucocorticoidsendotoxin lethality

D-galactosamine-sensitized mice, 970Glucosyltransferase operon fusion strains

S. mutans, 1259Glucosyltransferases

glucan-binding domain, 2899monoclonal antibodies, 323mutans streptococci

antibodies against active-site peptides,4814

S. mutans, 323streptococcimutans, 2899

GlucuronoxylomannanC. neoformans, 1340tolerance mechanisms, 1340

Glutamate-rich proteinimmunoglobulin M and G responses, 103P. falciparum, 103

Glyceraldehyde-3-phosphate dehydroge-nase

S. japonicum, 4716Glycoconjugate

lipid Amonoclonal antibodies, 4514

GlycolipidsM. avium, 1macrophage inhibition, 1

N-Glycolyl-GM3 ganglioside receptorE. coli, 4518K99 fimbriae

binding, 4518

Glycolytic enzymesC. albicans, 4263

GlycoproteinsP. carinii, 4703T. brucei, 4540

Glycosaminoglycan-binding proteinS. pyogenes, 3259

GlycosphingolipidsE. coli K88 fimbrial adhesin, 3673L. (L.) amazonensis amastigotes, 2131

Granulocytesinterleukin-8, 3111M. fortuitum, 3111

GranulomasIFN-y, 2872mycolic acid, 2872

gtf genesS. mutans

caries induction, 3811gtfB gene

S. mutans, 1563gtfC gene

S. mutans, 1563gtfS gene

S. downeinormal insoluble glucan synthesis,

1246gtfT gene

S. sobrinus, 2096Guanylin

E. coliheat-stable enterotoxin, 4710

Guinea pig modelLyme disease, 4777

Haemophilus ducreyiadherence

foreskin cells, 1735cytotoxin

neutralizing antibodies, 1589foreskin cells, 1735major outer membrane proteinOmpA family, 1346

Haemophilus genospeciesadherence, 4112neonatal, 4112

Haemophilus influenzaeC3

opsonization, 5157outer membrane protein binding sites,

5157chinchilla otitis media model, 1950immunoglobulin Al proteases

antigenic variation, 4575neutrophil migration inhibition

low-molecular-mass products, 2419outer membrane protein P5 gene, 4017outer membrane proteins

protection, 1950P5 gene, 4017pilus expression

paradoxical effect on antibody bind-ing, 3375

protein D, 3026protein D gene

encapsulated strains, 4546nonencapsulated strains, 4546

transferrin receptorelemental iron, 4033hemin, 4033

Haemophilus influenzae biogroup aegyp-tius

Brazilian purpuric fever associated, 1559Brazilian purpuric fever clone, 650lipooligosaccharide, 650pilin structural gene

Brazilian purpuric fever clone, 2233structural pilin gene, 1559virulence, 650

Haemophilus influenzae type bB-cell epitopes, 1867capsular polysaccharide antibodies

naturally acquired, 5345vaccine induced, 5345

OmpP2 proteins, 3966outer membrane protein antibodies

epiglottitis, 1531meningitis, 1531

P1monoclonal antibodies, 1867

P2 outer membrane proteinimmunogenicity of overlapping syn-

thetic peptides, 2653porin

expressed in B. subtilis, 3334recombinant, 3334

porin-deficient mutantreconstitution, 3966

vaccinesconjugate, 432suppression of antibody response, 432

Haemophilus somnus31-kilodalton-antigen gene

cloning, 2813sequencing, 2813

antibodybovine uterus, 2558

immunizationintramuscular, 2558

1ppB, 1793major outer membrane protein, 91

antigenic analysis, 2257outer membrane protein, 4153

heat modifiable, 1750Halofuginone lactone

C. parvumantibody responses, 4440

Heat shock cognate proteinL. donovani, 3265

Heat shock proteinsantibodies in S. aureus endocarditis pa-

tients, 1567E. coli, 1567M. bovis BCG

macrophage activation, 868M. leprae, 135mycobacterialHLA-DR molecules, 5294T cells, 5294

S. aureus, 1567Heat-labile enterotoxins

brefeldin A, 3282cholera, 3282E. coli, 3282

Heat-regulated proteinsL. donovani, 3265

Heat-stable enterotoxinsguanylin superagonist, 4710ST

immunization, 4629mucosal protection, 4629

SThantigenic determinants, 289

INFECT. IMMUN.

SUBJECT INDEX

epitope mapping, 289HeLa cellsH. pylon vacuolating toxin, 1427

Helicobacterfelisgastritis

active chronic, 2309immune responses, 2309

Helicobacter mustelaelipid receptors, 2632

Helicobacterpyloniadherence

epithelial cells, 350gastrointestinal cells, 4051

adhesinlipid binding, 2474receptor affinity purification, 2474

adhesion, 448gastric epithelial cells, 4058

antigenhigh molecular mass, 1799linkage to cytotoxin production, 1799

cagA, 1799iron acquisition, 2694lactoferrin, 2694lipid receptors, 2632lymphocytes

IFN--y production, 3012natural killer cell activity, 3012

minireview, 1601monkeys

experimental gastritis, 933Japanese, 933

pathogenicity, 1601polysaccharide

external, 2732immunoglobulin M monoclonal anti-

body, 2732superoxide dismutase, 5315urease

catalytically active recombinant, 2563expression in E. coli, 2563

vacuolating cytotoxinin vitro, 5008in vivo, 5008

vacuolating toxinATPase inhibitors, 1427HeLa cell response, 1427

Helper-T-cell epitopegroup A streptococcal M proteins, 1062

Hemagglutininsmannose-fucose resistant, 3032P. gingivalis, 940V. cholerae, 3032

HeminY pestis, 32

Hemin utilizationS. pneumoniae virulence, 5401

Hemoglobinendotoxin

distribution, 3209leptospires

chemotaxis, 2270stroma-free, 3209

HemolysinsE. coli, 1715S. aureus, 768T lymphocytes, 1715V. parahaemolyticus, 4326

Hemolytic uremic syndromeinterleukin-1l, 3886Shiga toxin, 3886

HEp-2 cellsactin accretion

calcium-calmodulin dependence, 760E. coli

enteropathogenic, 760Hepatic drug metabolism

pertussis toxin, 4240Hepatocyte cell line

L. monocytogenes multiplication, 3068Hepatocytes

L. monocytogenes, 2703lysis

leukocyte mediated, 2703listeriosis, 2703

Histoplasma capsulatumCD4+ T-cell clone, 714immunity

local, 4607lymph nodes

local immunity, 4607lung associated, 4607

protective immunitytransfer, 714

HlyAserological conservation, 1091

hlyA determinantsgenetic conservation, 1091

Human immunodeficiency virusmonocytoid cells, 1596T. gondii, 1596

Humoral immune responseN. meningitidis

class 3 outer membrane protein, 4734P. falciparum blood stage antigen gpl90,

40Hyaluronidase

streptococcigroup B neuraminidase, 3234

Hydrogen peroxideS. pneumoniae toxin, 4392

Hypothalamus-pituitary-adrenal axismycobacterial growth

regulation, 4793

iC3b receptorC. albicans, 1395

Ileal symbiont intracellularisporcine proliferative enteritis, 5237porcine proliferative enteropathy, 4286

Imidazolineoxyl N-oxideNO-dependent antimicrobial actionenhancement, 3552

Immune responsesminireview, 2273

Immune serumS. typhimunum, 3981

Immunityschistosomiasis, 4984

ImmunizationB. pertussis, 3190intranasal, 314S. choleraesuis

recombinant-plasmid mutant, 610S. mutans

antigen I/Il-cholera toxin B subunit,1964

T. foetussurface antigen TF1.7, 1385

T. gondiiantigens-cholera toxin, 2082

Immunoglobulin Al proteasesantigenic variation, 4575H. influenzae, 4575streptococci

dental plaque, 3998Immunoglobulin G receptor

neutrophils, 3533P. gingivalis, 3533

Immunoglobulin G-binding proteinsstreptococcigroup A, 1378, 3696

type II, 3696ImmunoglobulinsA. actinomycetemcomitans serotype b

immunodominant antigen, 2400IgA

anti-cholera toxin, 5279antilipopolysaccharide, 5279cholera toxin, 5271dental plaque bacteria, 3597monoclonal, 5271, 5279P. falciparum glutamate-rich protein,

103protective, 3597S. mutans, 1964salivary, 1964, 3597secretory, 3597

IgElymphatic filariasis, 2827

IgGA. actinomycetemcomitans fimbria

antigen, 332anti-O-specific lipopolysaccharide, 975B. burgdorfen complement-dependent

killing, 2532E. coli, 975Fab fragments, 2532monoclonal antibodies, 2493P. yoelii sporozoites, 2493T. pallidum opsonization, 781

IgMmonoclonal antibody, 910P. falciparum glutamate-rich protein,

103P. falciparum

maternal-cord sera, 988Immunoprotection

B. burgdorferi OspA- OspB- mutant,5115

In utero transmissionM. pulmonis, 2985

Indoleamine 2,3-dioxygenaseantitoxoplasma state, 1810

Inflammatory mediatorsperiodontitis

rhesus monkey, 1453Insulin

P. pseudomallei, 4045Integrin receptor vtP3M. avium-M. intracellulare

binding, 663macrophages, 663monocytes, 663

Interferonscandidiasis, 3530IFN-amonocyte lipopolysaccharide re-

sponses, 3222IFN-yA. fumigatus, 1185, 4870B. abortus, 4899C. parvum, 3928C. parvum infection in SCID mice,

VOL. 61, 1993

xxii SUBJECT INDEX

3548C. trachomatis, 491C. trachomatis pneumonia, 3556CD8' T cells, 3730costimulatory signal, 64F. tularensis, 689ylb T cells, 2154granuloma formation, 2872H. capsulatum, 1468H. pylori, 3012L. major, 3730L. monocytogenes, 2154leishmaniasis, 3459lipopolysaccharide, 1468mycobacterial defense, 3901natural killer cells, 3117neutralization, 689neutrophils, 1185nitric oxide production, 491nitrogen oxide synthesis, 689phospholipids, 3412R. prowazekii, 3412, 4317S. aureus, 3117salmonellosis, 4248T cells, 3098T. brucei, 3098T. gondii, 5174Y pestis virulence, 23

poly(I. C) induced, 3530regulatory factorsmonocyte lipopolysaccharide re-

sponses, 3222Interleukin-1 receptor antagonist

interleukin-113, 3342K pneumoniae newborn sepsis, 926S. epidermidis-induced hypotension,

3342tumor necrosis factor, 3342

InterleukinsIL-1

L. pneumophila, 4027listeriolysin 0, 1334macrophages, 1334pertussis cytopathology, 3123

IL-laE. risticii, 4333

IL-lphemolytic uremic syndrome, 3886IL-1 receptor antagonist, 3342S. epidermidis, 3342Shiga toxin, 3886

IL-2kala-azar, 3565L. pneumophila protease, 3416lymphocytes, 1486natural killer cell activity, 3565T. parva sporozoites, 1486

IL-4leishmaniasis, 3459pertussis toxin, 2834S. typhimurium aroA strain, 4818

IL-5anti-IL-2 antibodies, 1288CD4+ cells, 1288

IL-6cholera toxin, 4637cytokines, 4637E. coli S fimbriae, 3060E. risticii, 4333endocarditis, 5413L. monocytogenes, 2626lipopolysaccharide lethality, 3184lipopolysaccharide-galactosamine sep-

tic shock model, 1496P. carinii pneumonia, 97pentoxifylline, 2737Plasmodium antigens, 2737

IL-7L. major, 4008

IL-8adult respiratory distress syndrome,

4553blood, 4553epithelial cells, 4569lung, 4553M. fortuitum, 3111pneumonia, 4553urinary tract infections, 1307

IL-10M. avium, 3093staphylococcal enterotoxin B-induced

lethal shock, 4937Intestinal cells

C. jejuni invasivenessmodel, 2723

swine, 2723Intracellular adhesion molecule 1

E. coli S fimbriae, 3060Intracerebral infections

C. albicans, 3476C. neoformans, 3476

InvasionS. typhimunum, 5013

Iota-toxin genesC. perfringens, 5147

IpaBS. flexneri

B-cell epitopes, 3825ipgD gene

S. flexneri, 1707ipgF gene

S. flexneri, 1707IronH. pylon, 2694inorganic

Y. pestis, 32monocyte-macrophage stress response,

1281P. pseudomallei

malleobactin, 656S. aureus

phagocytosis, 1281S. epidermidis

slime production, 4473Y. pestis, 32

irp2 geneY. pestis

deletion, 2717Iscoms

T. gondii antigens, 2639

Kala-azarinterleukin-2, 3565natural killer cell activity, 3565

Kdo disaccharideendotoxinsrough type, 3616

synthetic analogbinding, 3616

KeratinocytesS. aureus alpha-toxin, 4972

Keyhole limpet hemocyanincholera toxin B subunit

female rat genital tract immune re-sponses, 2162

Kiebsiella pneumoniaecapsular polysaccharide biosynthesis

determinantsgenetic exchange, 4208

extracapsular polysaccharideenhancement of synthesis, 3164

interleukin-1 receptor antagonist, 926outer membrane proteinsClq binding, 852complement classical pathway activa-

tion, 852RmpA2, 3164sepsisnewborn, 926

Kupffer cellselimination, 1936P. berghei liver schizonts, 1936

L929 cellsC. burnetii, 4485R. prowazekii, 2383

Lactoferricinantibacterial activity, 719

Lactoferrinantibacterial activity, 719B. bronchiseptica

siderophore production mutant, 2698H. pylori

iron acquisition, 2694P. aeruginosa

cystic fibrosis, 5049peptide fragment

antibacterial activity, 719pepsin derived, 719

proteolytic cleavage, 5049Laminin

E. coli S fimbriae, 4480sialyloligosaccharide chains, 4480

LasRP. aeruginosa

apr, 1180exotoxin A, 1180

LatencyP. carinii, 5406

Latex particlesantigen coated, 3724M. lepraemonocyte responses, 3724

Legionella pneumophilagenes required for macrophage killing,

5361growth conditions

intra-amoebic and other, 3503growth restriction

permissive macrophages coculturedwith nonpermissive lipopolysac-charide-activated macrophages,5056

interleukin-1 activityantibody-mediated enhancement, 4027

macrophage infectionphenotypic modulation, 1320

major histocompatibility complexhypoexpression, 2803

multiplication, 4980proteaseCD4, 3416interleukin-2, 3416

surface properties, 3503tumor necrosis factor alpha, 4980

INFECT. IMMUN.

SUBJECT INDEX xxiii

Leishmania amazonensiscutaneous leishmaniasismast cell-deficient WIH" mice, 2242

cytokine levelsC57BU10 mice, 2952

vaccinia virusesGP46/M-2 vaccine, 3351

Leishmania (Leishmania) amazonensisamastigotes, 2131glycosphingolipid antigens

amastigotes, 2131monoclonal antibody, 2131

Leishmania donovaniheat shock cognate protein, 3265heat-regulated proteins, 3265monocytes

blood, 1330effector role, 1330

T-cell clonesThl- and Th2-like, 1069

visceral disease, 1069Leishmania major

amastigotes, 1553CD4+ T cells, 5205IFN-y, 3459, 3730interleukin-4, 3459interleukin-7, 4008lipophosphoglycan-deficient clone

avirulent, 5205macrophage receptors, 1553persistence, 220secondary infection, 3730T cellsCD8+, 3730

LeishmaniasisT-cell subsetsB cells, 2266macrophages, 2266TH1, 2266TH2, 2266

Leptospireschemotaxis, 2270hemoglobin, 2270

Leucocidin RS. aureus, 580

Leukemia inhibitory factormyelopoiesis

lipopolysaccharide stimulated, 418Leukocytes

staphylococcal enterotoxin B, 391Leukotoxin determinantsP. haemolytica

serotypes 1 to 16, 5001Leukotoxin gene

P. haemolytica-like organism, 2089LeukotoxinsA. actinomycetemcomitans

cell surface nucleic acids, 4878neutrophil-mediated injuryenhancement, 2618

P. haemolytica, 2618inhibition of expression, 3942

Leukotriene B4C. jejuni, 4885P. aeruginosa

intestinally induced immunity, 671Light reporter system

host-pathogen interactions, 640Limulus amebocyte lysate

lipopolysaccharide-binding proteins,1033

Lipid Adisaccharide backbone, 4514glycoconjugate

artificial, 4514immune response

rabbits, 680macrophage gene expression, 3518monoclonal antibodies

binding, 4514monoclonal antibody, 3873monoclonal antibody binding, 910monophosphoryl

lipopolysaccharide-inducible macro-phage gene expression, 2325

macrophage treatment, 2325R. sphaeroides, 3518rabbitsimmune response, 680

Lipid A analogsmacrophages

early gene expression, 2015Lipid receptorsH. mustelae, 2632H. pylon, 2632

Lipid vesiclesglycolipids, 335pertussis toxin

binding, 335Lipids

B. burgdorfen OspAimmunogenicity, 81

Lipoarabinomannanmacrophage effector functions, 4173mycobacterial strains, 4173

LipooligosaccharidesH. influenzae biogroup aegyptius

Brazilian purpuric fever clone, 650virulence, 650

N. gonorrhoeae mutantscomplementation, 3360

Lipopolysaccharide tolerancecytokine production

differential regulation, 4356Lipopolysaccharide-binding proteinsLimulus amebocyte lysate, 1033murine, 3.78

Lipopolysaccharidesapoptosis

thymus, 5044B. abortus, 1722binding, 1917C. albicans, 2216C. jejuni, 5384E. coli, 3863

uroepithelial cells, 3304endotoxin activities

inhibition, 3873IFN-yH. capsulatum, 1468

interleukin-6, 3184macrophage gene expression

dissociation, 2325monoclonal antibody

antiendotoxin, 1756anti-lipid A, 3873HA-1A, 1756immunoglobulin M, 1756

monoclonal antibody binding, 910, 3863monocytes

priming, 3222mononuclear phagocytes

activation, 4452neutrophils

apoptosis, 1972ingestion, 1972

O-polysaccharide chains, 5384P. haemolytica, 170paroxysmal nocturnal hemoglobinuria,

4280phagocyte responses, 4280platelets, 4182polymorphonuclear neutrophils

retrovirus-immunosuppressed mice,2216

rickettsiaespotted fever group, 4350

S. minnesotaantibodies, 3216

S. typhimunium, 5351Salmonella spp., 3863smoothmacrophage treatment, 2325

splenocyte p73 receptorpertussis toxin, 1359

toxicityeffector role for platelets, 4182

tumor necrosis factor alpha induction,1917

Y enterocolitica, 5261Lipoprotein genesH. influenzae type b, 4682P. haemolytica, 4682S. hyodysenteriae, 1136

LipoproteinsA. pleuropneumoniae, 565B. burgdorferi, 4158OspA, 3843OspB, 3843

high density, 5140low density, 5140M. fermentans, 3327M. hyorhinis, 2224M. intracellulare, 1074monokine release

endotoxin induced, 5140prevention, 5140

T. pallidum, 1202Liposomes

B. pertussis vaccine, 573Listenia ivanovii

actin polymerizationcell-to-cell spread, 162

Listeria monocytogenesActA polypeptide

localization, 2793aromatic amino acid-dependent mutant,

2245auxotrophic mutants

intracytoplasmic growth, 3756virulence, 3756

,2 microglobulin-deficient mice, 1113Clq

phagocytosis, 3664C3, 0

proteolysis, 5134complement alternative pathway

activation, 5134cytokine mRNA expression, 3739cytokinesgene expression, 2545release, 2545

hepatocytesleukocyte-mediated lysis, 2703

IFN-y secretiony/8 T cells, 2154

interleukin-6

VOL. 61, 1993

xxiv SUBJECT INDEX

cellular source, 2626listeriolysin gene expression, 3073monoclonal antibody

anti-CD3, 2786multiplication

hepatocyte cell line, 3068natural killer cells, 2703neutrophils, 5090nonspecific resistance, 5090phosphatidylcholine phospholipase C

maturation, 1576PrfA regulator, 3073prfA transcriptional activator

regulation, 2537prfA-independent promoter, 3073T cellsCD4+ CD8+ Thyl.2+, 2703

zinc metalloprotease, 1576Listeriolysin gene expressionPrfA regulator, 3073prfA-independent promoter, 3073

Listeriolysin 0macrophages

interleukin-1, 1334membrane damage, 1334

IppB geneH. somnus, 1793

Lyme arthritisB. burgdorfei OspA and OspBimmune responses, 2774

HLA-DR4, 2774treatment resistant, 2774

Lyme diseaseguinea pig model, 4777rhesus monkeys, 3047

Lyme disease spirochetesosp genes

variability, 2611outer surface proteins

variability, 2611Lymphocyte blast transformation

C. pneumoniae, 2196Lymphocyte proliferation

C. neoformans, 464human, 464

LymphocytesH. pylon, 3012

IFN--y production, 3012natural killer cell activity, 3012

staphylococcal enterotoxin B, 391Lysozyme-specific mRNAGG2EE macrophages, 3605tetanus toxin, 3605upregulationIFN-y mediated, 3605prevention, 3605

M proteinhelper-T-cell epitope, 1062streptococcigroup A, 2277pharyngeal colonization, 2277

T-cell activationantigen-presenting cells, 785

Macrophage effector functionslipoarabinomannan, 4173mycobacterial strains, 4173

Macrophage gene expressionlipopolysaccharide induced, 3518R. sphaeroides lipid A, 3518SDZ 880.431, 3518

MacrophagesA. fumigatus

acquired immunity, 3791anthrax lethal toxin, 245antimicrobial proteins, 3038apoptosis, 4064B. pertussis, 4064C. difficile toxin B, 1082E. risticii

killing, 861early gene expression, 2015eicosanoids, 1432GG2EE

tetanus toxin, 3605H. capsulatum, 1468IFN-y treated, 1141inflammation-primed activation

albumin, 5388vitamin D3-binding protein, 5388

interleukin-1, 1334L. pneumophila

genes required for killing, 5361growth restriction, 5056phenotypic modulation, 1320

lipid A analogs, 2015lipopolysaccharide-inducible gene

expressiondissociation, 2325

listeriolysin 0, 1334M. avium

glycolipid fractions, 1M. tuberculosis, 2763membrane damage, 1334peritoneal, 1432

E. risticii, 861mycobacterial 65-kDa heat shock pro-

tein, 868receptors

L. major amastigotes, 1553T. gondii, 1432, 4126

bradyzoite-specific antigens, 1141T-cell subsets

leishmaniasis, 2266TH1, 2266TH2, 2266

Major histocompatibility complexhypoexpression, 2803L. pneumophila

phagolysosomes, 2803phagosomes, 2803

Major histocompatibility complex class Iand class II molecules

E. colicompartmentalization of defined

epitopes, 4848Major histocompatibility complex class II

moleculesB. malayi, 5410E. coli S fimbriae, 3060eosinophils, 5410

Major histocompatibility complex genesM. bovis BCG culture filtrate antigens

antibody repertoire, 2687Major outer membrane protein gene

C. psittaci, 3078C. trachomatis, 213

Major outer membrane proteinsC. trachomatis, 4093H. ducreyi, 1346H. somnus, 2257M. catarrhalis, 2003R. tsutsugamushi

Sta58, 4527

Malleobactiniron acquisition, 656P. pseudomallei, 656

MannansC. albicans, 2122

adherence of yeast forms, 2578delayed hypersensitivity, 2122

MannoproteinsC. albicans

anti-complement receptor type 2 anti-bodies, 4675

blastoconidia, 4675hyphae, 4675

Mannose-binding proteinC. neofonnans, 4891

Mast cell-deficient WIW' miceleishmaniasis

cutaneous, 2242Memory immune responseM. tuberculosis, 844

Mesocestoides cortistress protein release

active export, 2596brefeldin A inhibitable, 2596

MetalloproteaseA. fumigatus, 4099

Microtubule inhibitorsC. parvum, 4888

Migration inhibitory factorM. avium

inhibition of growth, 338Minireviews

antigenic variation, 2273coevolution

pathogen-host, 2273epithelial colonization, 4941H. pylori

pathogenicity, 1601immune response, 2273peptidoglycan-polysaccharide polymers

bacterial cell walls, 4535phlogistic properties, 4535

sepsisanimal models, 2741choice of bacteria, 2741

Shigella subversion of cellular cytoskele-ton, 4941

T. gondii, 1169Yops

Yersinia spp., 3105MitogensY pseudotuberculosis, 3922

MitomycinShiga-like toxin

induced synthesis, 4510MonkeysJapaneseH. pylori gastritis, 933

Monoclonal antibodiesantiendotoxin immunoglobulin M, 1756B. burgdorferi

39-kDa protein, 4523B. burgdorferi OspA, 423C. albicans cell wall antigens, 4842C. immitis antigen 2, 1895C. parvum, 4906C. trachomatis

neutralization, 498C. trachomatis C-complex serovar outer

membrane protein variable domainI, 1365

CD3, 2786diphtheria toxin

INFECT. IMMUN.

SUBJECT INDEX xxv

structure-function analyses, 994E. histolytica galactose adhesin, 1772Fc-yRII, Fc-yRIII specific, 4925H. influenzae type b P1 specific, 1867H. pylori external polysaccharide, 2732H. somnus outer membrane protein,

4153HA-1A, 1756

antibiotics, 512binding to smooth gram-negative bac-

teria, 512heat-stable enterotoxinsSTh, 289

immunoglobulin G, 2493immunoglobulin M

binding to lipopolysaccharide and lipidA, 910

L. (L.) amazonensis amastigote gly-cosphingolipid antigens, 2131

L. monocytogenes, 2786lipid A, 3873, 4514lipopolysaccharides, 1756

E. coli, 3863Salmonella spp., 3863

P. yoelii sporozoites, 2493S. mutans glucosyltransferase, 4689S. mutans glucosyltransferases, 323T. cruzi, 4925U. urealyticum antigens

serotype 4 specific, 2253Monocyte chemoattractant protein 1

gingival tissuesinflamed, 4622

periodontal disease, 5219Monocytes

antimycobacterial activity, 4501C. difficile toxin B, 1082leishmaniasis

visceral, 1330lipopolysaccharide responses

priming, 3222M. bovis BCG, 4501M. leprae, 3724

Monocytes-macrophagesS. aureus, 1281stress response

differentiation, 1281iron, 1281

Monokine releaseendotoxin induced

prevention, 5140lipoproteins, 5140

Mononuclear phagocytesactivation

lipopolysaccharide, 4452lipopolysaccharide, 4452

Monophosphoryl lipid AC. albicans mannan

delayed hypersensitivity, 2122Moraxella catarrhalis

major outer membrane protein, 2003pulmonary clearance, 2003

Mouse large intestineE. coli, 1293

MPB64 geneM. bovis BCG, 1730

mry-like geneS. pyogenes, 5426

msm operoncloning, 1121S. mutans, 1121

MucinC. albicans

adhesion, 1940Y enterocolitica, 4131Y enterocolitica adhesion, 2340

Mucosal immune systemmice, 303segmented filamentous bacteria, 303

Mucosal immunitystreptococcal surface protein antigen-

cholera toxin B subunitintranasal immunization, 314

Mucusileal

piglet, 2526receptors

E. coli K88 fimbriae, 2526glycolipid, 2526protein, 2526

Mudlux transcriptional fusionhydrogen peroxide, 640light emission, 640macrophage cell line J774.2, 640S. typhimurium, 640

Mutans streptococciglucosyltransferases

antibodies against active-site peptides,4814

Mycobacteriaantigen 85 complex

armadillo tissue, 1835epitopes, 1835leprosy lesions, 1835

antigens, 1509lipoarabinomannan, 4173M. leprae 18-kDa-antigen homologs,

1509M. tuberculosis 19-kDa-antigen ho-

mologs, 1509macrophage effector functions, 4173

Mycobacterial antigen complex A60T-cell repertoire, 439tuberculosis, 439

Mycobacterial growthhypothalamus-pituitary-adrenal axis,

4793Mycobacterial heat shock proteinsT cellsHLA-DR molecules, 5294

Mycobacterium aviuma-antigen

B-cell epitopes, 1173a-antigen gene, 1173anti-interleukin-10 antibody, 3093glycolipid fractionsmacrophage inhibition, 1

interleukin-10, 3093lipid fractionsimmunomodulation of peripheral blood

mononuclear cell functions, 5286migration inhibitory factor, 338phagosome-lysosome fusiongrowth restriction, 3775

serovar 2M. paratuberculosis 18, 1

Mycobacterium avium complexnitric oxide resistance, 1980

Mycobacterium avium-Mycobacterium in-tracellulare

integrin receptor av13

macrophages, 663monocytes, 663

Mycobacterium bovis85B secreted protein, 4828defense

cell contact, 3901interleukin-1p, 3901tumor necrosis factor, 3901

fibronectin, 4828Mycobacterium bovis BCG

antigen complex45/47-kDa, 742

antigen presentationdendritic cells, 5326

culture filtrate antigensantibody repertoire, 2687

heat shock protein65 kDa, 868macrophage activation, 868

major histocompatibility complex genes,2687

monocyte antimycobacterial activity,4501

MPB64 geneabsence, 1730

ribosomal proteinsimmunological properties, 4005

vaccination, 4501Mycobacterium fortuitum

granulocytesnonoxidative intracellular killing, 3111

interleukin-8, 3111Mycobacterium intracellulare

lipoprotein27 kDa, 1074

Mycobacterinum lepraeantigen

serine rich, 2145antigen 85 complex

armadillo tissues, 1835leprosy lesions, 1835

antigen 85 complex gene family, 3642heat shock protein

70 kDa, 135B-cell epitopes, 135variable C-terminal region, 135

monocyte responsesantigen-coated latex particles, 3724

Mycobacterium smegmatisM. tuberculosis 19-kDa antigen, 260

Mycobacterinum tuberculosisA60 antigen complex-specific T-cell rep-

ertoire, 439antigen

19 kDa, 260expression in M. smegmatis, 260glycosylation, 260

cord formationtrehalose 6,6'-dimycolate model, 2296

cytokine productionsite of disease, 3482

cytolytic activitycontact dependent, 2708genomic locus, 2708

macrophagesinteraction, 2763

memory immune responseprotective, 844

proteintumor necrosis factor inducing, 627

trehalose 6,6'-dimycolate model, 2296tumor necrosis factor-inducing protein,

627vitamin D

cell-mediated hypersensitivity, 2116

VOL. 61, 1993

xxvi SUBJECT INDEX

resistance, 2116Mycobacterium vaccae

adhesinfibronectin, 1889

Mycobacterium-reactive T-cell clonescytokine production, 197

Mycolic acidgranuloma formation, 2872

Mycoplasma arthritidisattachment mechanisms, 2670

Mycoplasma fermentansantigenic variation

high frequency, 5123lipoproteins

strain variant, surface, 3327Mycoplasma gallisepticumpMGA gene family member, 903

Mycoplasma hominiscytoadhesins, 2945

Mycoplasma hyorhinisantigenic variation, 2224lipoproteins, 2224

Mycoplasma pneumoniaeP1 cytadhesin gene

sequence divergence, 816protein

90 kDa, 1523terminal tip structure, 1523

Mycoplasma pulmonisgenital, 633in utero transmission, 2985resistance

genetic control, 4615mice, 4615

Sprague-Dawley rats, 633Mycoplasma species

arginine deiminasegene polymorphism, 329

Myelopoiesisleukemia inhibitory factor, 418lipopolysaccharide, 418tumor necrosis factor alpha, 418

Myosin heavy chain AE. histolytica, 1048

Natural killer cell activityH. pylori, 3012interleukin-2, 3565kala-azar, 3565

Natural killer cellsC. albicans, 3769candidiasis

gastrointestinal, 2520intraperitoneal administration, 2520scid mice, 2520

CD4+ subset differentiation, 3769IFN--y, 3117listeriosis, 2703S. aureus, 3117

Neisseria gonorrhoeaecatalase, 1232catalase-deficient strain, 1232cytidine 5'-monophospho-N-acetyl-

neuraminic acid, 1657fur homolog, 4599lipooligosaccharide defect complementa-

tion, 3360piLA mutants

serum resistance, 4662pyocin mutants, 3360serum resistance, 1657

Neissena meningitidisFrpA

extracellular secretion, 2906lipopolysaccharide-specific antibodies,

187oligosaccharide-protein conjugates

adjuvants, 187lipooligosaccharide derived, 1873

outer membrane protein98 kDa, 4724antigenic hybrids, 4217class 1, 4217class 3, 4734humoral immune response, 4734iron regulated, 4724

outer membrane protein-specific antibod-ies, 187

polyphosphate kinase, 3703transferrin receptors, 751

NeuraminidasesB. fragilis, 4415hyaluronidase, 3234P. haemolytica, 253, 4669streptococcigroup B, 3234

Neutrophil complement receptorsstreptococcigroup B capsular polysaccharide, 2866

NeutrophilsA. fumigatus, 1185, 4870antibacterial polypeptides, 966apoptosis, 1972C. neoformans, 5067colony-stimulating factor

granulocyte, 1972complement, 3533E. coli

superoxide dismutase, 1442Fc receptor, 1415immunoglobulin G receptor, 3533inflammatory mediator release

S. pyogenes erythrogene toxin A, 1055toxic shock syndrome toxin 1, 1055

ingestion, 1972L. monocytogenes, 5090lipopolysaccharide, 1972migration inhibition

nontypeable H. influenzae products,2419

mobility, 5067osmolality, 8P. aeruginosa

intestinally induced immunity, 671P. gingivalis, 3533pH, 8protein kinase C activity

calcium dependent, 3137localized juvenile periodontitis, 3137

streptococcitype III group B, 1415

urineosmolality, 8pH, 8

NF-KB DNA-binding activityS. flemnenHeLa cell invasion, 4427

Nitric oxideM. avium complex, 1980resistance, 1980

Nitric oxide productionC. trachomatis, 491IFN-y, 491McCoy cells, 491

Nitric oxide synthase pathwayR. prowazekii inhibition, 4317

Nitrogen oxidesF. tularensis, 689IFN-y, 689synthesis

blockage, 689tumor necrosis factor alpha, 689

NO-dependent antimicrobial actionenhancement, 3552imidazolineoxyl N-oxide, 3552

Nocardia asteroidescapillaries

attachment, 955penetration, 955

glia cells, 343ultrastructure

brain, 274

Oligomannosides3(1-2) linked, 1164C. albicans, 1164immunoglobulin G3 epitopes

C. albicans antigen, 1164Oligosaccharide-protein conjugatesN. meningitidis, 1873

omp2 gene locusB. abortus, 3785

OmpAP. mirabilis, 4915

OmpA familyH. ducreyi major outer membrane pro-

tein, 1346OmpC

S. flexneninvasiveness, 3625

OmpP2 proteinsH. influenzae, 3966

Opacity variantsgroup B streptococci

interaction with host defense system,3761

Opaque-phase-specific genesC. albicans, 1823

OpsonizationT. pallidum, 781

Osmolalityneutrophil activity in urine, 8

osp genesLyme disease spirochetes, 2611

OspB mutantB. burgdorferi, 3590

OspCB. burgdorferi, 2182

ospC geneB. burgdorferi circular plasmid, 2192

Osteomyelitisstaphylococcal

rat model, 5225Otitis mediaH. influenzae, 1950polymorphonuclear leukocyte migration

modulation with anti-CD18 antibody,1132

Outer membrane lipoprotein OmlAA. pleuropneumoniae, 565

Outer membrane protein antibodiesepiglottitis, 1531H. influenzae type b, 1531meningitis, 1531

Outer membrane protein P5 geneH. influenzae, 4017

INFECT. IMMUN.

SUBJECIT INDEX xxvii

Outer membrane proteinsA. hydrophila, 371A. marginale

MSP4, 5245H. influenzae

protection, 1950H. influenzae type b, 2653H. somnus, 91, 1750, 4153N. meningitidis, 4217

class 3, 4734iron regulated, 4724

P2, 2653P. mirabilis

B-lyphocyte mitogen, 4915OmpA protein, 4915

YadA, 2513yersiniae

enteropathogenic, 2513Outer surface proteins

B. burgdorferi, 2207Lyme disease spirochetes, 2611

P1 cytadhesin genesequence divergence, 816

p23B. burgdorferi

North American strain, 5097pap-, sfa-, and afa-related gene clusters

E. colibovine and porcine isolates, 2453F165 positive, 2453

Paroxysmal nocturnal hemoglobinurialipopolysaccharide

impaired phagocyte responses, 4280Pasteurella haemolytica

ATP-binding cassette homolog, 3942leukotoxinenhancement of neutrophil-mediated

injury, 2618inhibition of expression, 3942

leukotoxin determinantsserotypes 1 to 16, 5001

lipopolysaccharidesspecificities, 170

lipoprotein genesH. influenzae type b lipoprotein gene,

4682neuraminidase, 253neuraminidases, 4669

Pasteurella haemolytica-like organismleukotoxin gene, 2089RTX toxin family, 2089

Pasteurella multocidaadherence, 4785capsulated, 4785noncapsulated, 4785virulence, 4785

Pathogen-host coevolutionminireview, 2273

PCFO20E. coli fimbrial putative colonization fac-

tor, 5190Penicillin-resistant pneumococci

molecular epidemiology, 4382Pentoxifylline

interleukin-6, 2737Plasmodium antigens, 2737tumor necrosis factor, 2737

pep M5peripheral blood mononuclear cells

cytokine release, 1194

Peptidasesstreptococcimutans group, 182

PeptidesY pestis

low-calcium response, 13Peptidoglycan-polysaccharide polymers

arthritisreactivation, 4645

bacterial cell walls, 4535cell walls, 4645minireview, 4535phlogistic properties, 4535

Peptidoglycansstaphylococci, 4167tumor necrosis factor, 4167

Periodontal diseasemonocyte chemoattractant protein 1,

5219Periodontal flora

environment, 2891genetics, 2891puberty, 2891teenagers, 2891

Periodontitisinflammatory mediators

rhesus monkey, 1453localized juvenile, 3137protein kinase C activity

calcium dependent, 3137neutrophils, 3137

Peripheral blood mononuclear cellsC. albicans mannoprotein, 4105cytokine gene expression, 4105cytokine release, 1194M. avium lipid fractions

immunomodulation, 5286pep M5, 1194

PertactinB. pertussis, 2211

Pertussisepithelial cytopathology, 3123IL-1, 3123

Pertussis toxinanalogsB oligomer, 2316

B-oligomer-subunit mutations, 2316hepatic drug metabolism

alterations, 4240interleukin-4, 2834lipid vesicles

binding, 335glycolipids, 335

S4 subunitB-cell epitopes, 2408T-cell epitopes, 48, 56

splenocyte p73 receptorlipopolysaccharide, 1359

pHneutrophil activity in urine, 8

PhagocytesC. neoformans, 3818endothelial cells, 3818lipopolysaccharide, 4280paroxysmal nocturnal hemoglobinuria,

4280Phagocytic cells

S. flexneri type 1 fimbriae, 1687Phagocytosisnonopsonic

P. aeruginosa, 3287P. aeruginosa, 3287streptococci

group B, 2334streptococci, 2334

Phagosome-lysosome fusionM. avium growth restriction, 3775

Phosphatidic acidC. perfringens

alpha-toxin-induced hemolysis, 3711Phosphatidylcholine phospholipase C

L. monocytogenes, 1576Phospholipase C

phosphatidylinositol specific, 5078S. aureus, 5078

Phospholipase DA. haemolyticum, 4310C. pseudotuberculosis, 4310

PhospholipasesB. thuringiensis

avirulent pleiotropic mutant, 4947eicosanoids, 1432T. gondii penetration, 1432

PhospholipidsIFN-y, 3412R. prowazekii, 3412

PhospholipomannanC. albicans antigen, 4398

Phosphoribosylaminoimidazole carboxyl-ase gene

C. neoformanscerebrospinal fluid, 4446

Piglet modelcampylobacteriosis, 3466

pilA mutantsN. gonorrhoeae

serum resistance, 4662PiliH. influenzae

antibody binding, 3375P. aeruginosa

gene cluster, 1371immune recognition, 3527polar, 3527

V. cholerae non-O1, 5398Pilin

P. cepacia binding, 3157Pilin genes

E. corrodens, 1909H. influenzae biogroup aegyptius, 1559

Pilin structural geneH. influenzae biogroup aegyptius

Brazilian purpuric fever clone, 2233987P pilus genes

E. colienterotoxigenic, 2249

plasmid and chromosomal copies, 2249PK488 adhesin geneA. naeslundii coaggregation adhesin

gene, 981S. gordonii, 981

Plasmidsincompatibility groups P and QA. actinomycetemcomitans, 3544conjugal transfer, 3544E. coli, 3544

S. choleraesuis, 610S. dublinpSDL2, 705

S. typhimuriumgrowth rate, 504virulence, 504

Plasmodium antigensinterleukin-6, 2737pentoxifylline, 2737tumor necrosis factor, 2737

VOL. 61, 1993

xxviii SUBJECT INDEX

Plasmodium bergheiKupffer cells

elimination, 1936schizonts

liver, 1936Plasmodium falciparum

antibodiesisotypic analysis, 4498

antigensconservation, 892erythrocyte surface, 284protective, 892

Aotus monkeysprotective immunity, 2041, 2048

blood stage antigen gpl90humoral immune response, 32

circumsporozoite proteinantibody responses, 2425B-cell epitopes, 2425

cross-reactive antigen(s)erythrocytic stage, 4863inhibition of parasitemia, 4863

cytoadherencemodulation by cytokines, 5198

cytotoxic T lymphocytescircumsporozoite protein, 5062

erythrocyte-binding antigen 1, 268erythrocytes

binding to CD36, 2229rosetting, 284surface antigens, 284

Gambian childrenclinical immunity, 103

glutamate-rich proteinimmunoglobulin M and G responses,

103gpl90

humoral immune response, 32, 40humoral immune response, 40immunoglobulins

maternal-cord sera, 988Madagascar, 4498merozoite proteins

T-cell recognition, 268merozoite surface protein 1

baculovirus, 3403cross-reactivity, 3403C-terminal 42-kDa fragment, 3403

p82 rhoptry proteinantibodies, 2960

p126, 3933proteins

conservation of protective antigencomponents, 892

hybrid, 892RESA-2 gene

transcription, 4469rhoptry associated protein 1, 268rosetting, 5198SERA protein

adjuvant effects, 2041, 2048immunogenicity, 3933recombinant, 2041, 2048

T cells, 4863thrombospondin-related anonymous pro-

teinantibody response, 3490

tumor necrosis factor, 4772virulence factors, 5198

Plasmodium vinckei vinckeiT-cell lines

preprocessed antigens, 1958

Plasmodium yoeliiC-reactive protein

transgenic mice, 348cross-reactive antigen(s)

erythrocytic stage, 4863inhibition of parasitemia, 4863

monoclonal antibodiesimmunoglobulin G, 2493

sporozoites, 348, 2493T cells, 4863

Plasmodium yoelii yoeliimerozoite surface protein 1

protective immune response, 2462recombinant fragment, 2462

Platelet-activating factorantagonist, 699carrageenan-treated mice, 699pneumonia

bacterial, 1996polymorphonuclear neutrophil granulo-

cytes, 1996R. prowazekii, 2024tumor necrosis factor

endotoxin induced, 699suppression, 699

Plateletslipopolysaccharide-induced toxicity,

4182pMGA gene family memberM. gallisepticum, 903

Pneumocystis cariniiantigenic differences, 1315ferrets, 1315genetic stability and diversity

rat colonies, 4801glycoproteinmajor surface, 4703proliferative and cytokine responses,

4703immunotherapy

cell mediated, 1641humoral, 1641

interleukin-6, 97latency, 5406mice, 1315pneumovirus concurrent infection, 1586rats, 1315scid mice, 1586, 1641transmission

restricted, 2886vitronectin

binding, 4302Pneumolysin

immunoreactive sitesmapping, 2822

pulmonary alveolar epithelial cells, 1352Pneumonia

interleukin-8, 4553P. carinji

interleukin-6, 97platelet-activating factor, 1996

PneumonitisC. pneumoniaemouse model, 2037

PneumovirusP. carinii concurrent infection

scid mice, 1586Pnu-Imune vaccine

dehydroepiandrosterone, 2238immune response

reversal of age-associated decline,2238

Poliovirus hybridC. trachomatis major outer membrane

protein neutralization epitope, 4406Polymorphonuclear leukocytes

migration modulationanti-CD18 antibody, 1132

otitis media, 1132T. foetus, 2995

Polymorphonuclear neutrophil granulo-cytes

platelet-activating factor, 1996Polymorphonuclear neutrophils

C. albicans, 2216retrovirus-immunosuppressed mice, 2216

Polypeptidesantibacterial, 966

Polyphosphate kinaseN. meningitidis, 3703

Polysaccharidesbinding, 1917capsular

neutrophil complement receptor inter-actions, 2866

type III group B streptococci, 2866H. pylori, 2732K pneumoniae

extracapsular, 3164S. aureus

type 8 capsular, 1853streptococci

capsular, 478, 4835endothelial cell invasion, 478group B, 478, 4835

tumor necrosis factor alpha induction,1917

V. vulnificuscapsular, 2053immunogenicity, 2053

Population structuresP. gingivalis, 204

Porcine proliferative enteritisIleal symbiont intracellularis, 5237

Porcine proliferative enteropathyIleal symbiont intracellularis, 4286

Porin-lipopolysaccharidesalmonellosis

protective immunity, 3017Porins

B. abortus, 3785H. influenzae type b

B. subtilis, 3334S. typhimurium

cytokine release, 155Porphyromonas gingivalis

cell surface antigenrecombinant and native forms, 3294

epithelial cellsinteractions, 2260

fibroblast-activating factor, 580, 596bone resorption, 3562

fimbrial components, 5181fimbrillin

expression in E. coli, 3570recombinant, 1040

genetic structure of populations, 204hemagglutinin

S. typhimurium, 940neutrophilscomplement, 3533immunoglobulin G receptor, 3533

phagocytosis inhibition, 3533protease

salt-solubilized collagen degradation,

INFECT. IMMUN.

SUBJECT INDEX xxix

2369protease-deficient mutant, 4139prtT gene, 117tpr gene product, 4139

PR-39E. coli, 2978mechanism of action, 2978

PRB3 null mutationsF. nucleatum

interactions with saliva, 4434proline-rich glycoprotein GI, 4434

Prevotella intermediaActinomyces spp.

coaggregation, 2011oral, 2011

prfA transcriptional activatorL. monocytogenes, 2537regulation, 2537

Prostaglandin E2C. jejuni, 4885E. risticii, 4333

Proteasesaspergillosis, 2357elastolytic serine, 2357L. pneumophila, 3416P. gingivalis

salt-solubilized collagen, 2369serine

inhibition by eNAP-2, 2991Protein DH. influenzae, 3026

Protein D geneH. influenzae

encapsulated, 4546nonencapsulated, 4546

Protein kinase Ccalcium dependent, 3137localized juvenile periodontitis, 3137neutrophils, 3137

Protein synthesis inhibitionSalmonella invasion, 1544

Proteinasesalpha-2-macroglobulin, 5035sepsisbaboon model, 5035

Proteinsantimicrobial, 3038B. burgdorfen, 4523C. albicans, 1881C. parvum sporozoites

shared epitopes, 2377Cryptosporidium oocysts, 2347E. chaffeensis, 3536lipopolysaccharide binding, 378M. pneumoniae, 1523macrophages

murine, 3038P. falciparum

merozoite surface protein 1, 3403P. yoelii yoelii merozoite surface protein

1protective immune, 2462recombinant fragment, 2462

S. aureusextracellular matrix binding, 2479

S. dublinvirulence, 705

S. epidermidiscell envelope, 1743

Yersinia spp., 71YopB, 71YopD, 71

Proteus mirabilisfimbriae

genes, 884subunit, 884

OmpA39-kDa outer membrane protein, 4915B-lymphocyte mitogen, 4915

ureaseascending urinary tract infection, 2748hydrolysis, 2570nickel ion binding, 2570

prtT geneP. gingivalis, 117

Pseudomonas aeruginosaadherence inhibition

alginase, 4338antibiotics, 4338monoclonal antibodies, 4338

alginateimmunosuppression, 559

asialo GM1corneal glycolipid receptor, 5164

biofilms, 777cathepsin G

synthetic peptides, 1900corneal infectionserum and ocular antibody responses,

2713cystic fibrosis

transferrin and lactoferrin proteolyticcleavage, 5049

elastaseparacellular permeability, 2681site-directed mutagenesis, 1400

exoenzyme S, 307exopolysaccharide

mucoid, 777exotoxin Adomain Ib and III fragments, 5417immunochemistry, 5417septicemia, 2468

intestinally induced immunityleukotriene B4, 671lungs, 671neutrophils, 671

mucoid exopolysaccharide, 559phagocytosis

nonopsonic, 3287piligene cluster, 1371immune recognition, 3527polar, 3527

pyocyaninciliary beat, 2848

virulence-associated genesent, 1571Jbp, 1571fliA, 1571fliC, 1571map localization, 1571pilA, 1571pilR, 1571rpoN, 1571

Pseudomonas cepaciabinding, 3157pilin, 3157

Pseudomonas pseudomalleiinsulin, 4045malleobactin

iron acquisition, 656Pyelonephritis

anti-idiotype antibodies, 2289primate model, 2289

renal scarringprevention, 5214

vaccinationE. coli oligosaccharide-protein conju-

gate, 5214Pyocin mutantsN. gonorrhoeae

complementation, 3360Pyocyanin

ciliary beat, 2848P. aeruginosa, 2848

Q fevervaccine

chloroform-methanol residue, 1251

Rabbitslipid Aimmune response, 680

Rainbow trout actinADP-ribosylation, 5392botulinum C2 toxin, 5392

ReceptorsavP3, 663E. coli K88 fimbriae, 2526integrin, 663M. avium-M. intracellulare, 663macrophages

L. major amastigotes, 1553mucus

piglet ileal, 2526N. meningitidis, 751transferrin, 751tumor necrosis factor alpha, 830

Reproductive systemC. bumetii, 4188

RESA-2 geneP. falciparum, 4469transcription, 4469

Rhesus monkeysLyme disease, 3047

Rhodobacter sphaeroideslipid Amacrophage gene expression, 3518

Rhodococcus equibindingcomplement receptors, 2919

CD4+ T-lymphocyte-deficient transgenicmice, 4929

Mac-1, 2919pulmonary clearance

failure, 4929Rhoptry-associated protein 1

B. bovis, 3511B-cell epitopesimmunogenic, 3511

Ribosomal proteinsM. bovis BCG, 4005

Rickettsia prowazekiiDNA synthesis, 2383inhibition of growthL929 cells, 4317nitric oxide synthase pathway, 4317

L929 cellsIFN-y treated, 2383untreated, 2383

phospholipidsIFN--y, 3412L929 cells, 3412

platelet-activating factor synthesisstimulation, 2024

protein synthesis, 2383

VOL. 61, 1993

xxx SUBJECT INDEX

rRNA synthesis, 2383Rickettsia tsutsugamushi

antigensprotein, 1674T-cell response, 1674

major outer membrane protein StaS8epitope mapping, 4527

T-cell response, 1674Rickettsiae

spotted fever groupdirectional actin polymerization, 1926lipopolysaccharides, 4350

RosettingP. falciparum, 5198

RTX toxin familyP. haemolytica-like organism, 2089

Saccharomyces cerevisiaeCandida factor 1 and 9 antisera

epitopes recognized, 3313mnn mutants, 3313

Salivary agglutininS. gordoniiSspA gene, 3199

Salmonella abortusovisTnphoA mutants

adherence, 1786virulence, 1786

Salmonella choleraesuisrecombinant-plasmid mutantimmune responses, 610

Salmonella dublinaroA 04-09 hybrid

vaccination, 1211aromatic-dependent hybrid

vaccination, 1222plasmidspSDL2, 705

pSDL2, 705spvB, 5231vaccinesaroA 04-09 hybrid, 1211aromatic-dependent hybrid, 1222

virulence proteinspSDL2, 705SpvA, -B, and -C, 705stress induction, 705

Salmonella minnesotalipopolysaccharide

antibodies, 3216Salmonella muenchen

flagellar antigen dT-cell epitopes, 1146

Salmonella spp.lipopolysaccharidesmonoclonal antibody, 3863

Salmonella typhiadherencegrowth phase, 3084osmolarity, 3084regulation, 3084

vaccinesThai children, 1149Ty2la, 1149

Salmonella typhimuriumacid tolerance response genes, 4489adhesion, 5013adoptive transfer of immunityBALB/c mice, 3981immune serum, 3981T cells, 3981

aroA strain, 4818

cytokine releaseporins, 155

growth phase, 5013growth rate, 504interleukin-4 genearoA strain, 4818

invasion, 1544, 5013lipopolysaccharide

physical state, 5351Mudlux transcriptional fusion

light emission, 640multiplicity of infection, 5013mutantsAaroA AaroD, 5374

P. gingivalis hemagglutinin, 940plasmid

virulence, 504porin-lipopolysaccharide

protective immunity, 3017porins

cytokine release, 155protein synthesis, 5013protein synthesis inhibition

invasion, 1544T lymphocytes

cytotoxic, 5374major histocompatibility class I re-

stricted, 5374vaccine strains

S. sobrinus antigen fusions to E. coliheat-labile toxin subunit B, 1004

Salmonella virulence plasmid gene spvBmacrophages, 5231nonphagocytic cells, 5231

SalmonellosisIFN-,y

role in late stages, 4248Schistosoma japonicum

anti-interleukin-2 antibodies, 1288eosinophilia, 1288glyceraldehyde-3-phosphate dehydroge-

nase, 4716hepatic fibrosis, 1288interleukin-5 secretionCD4' cells, 1288

Schistosoma mansoniantigens

candidate vaccine, 146cercariae

irradiated, 3003vaccination, 146

cholera toxineffect on vaccine-induced immunity

and infection, 4919fibroblast-stimulating factor 1

egg granulomas, 3985T-cell receptorCD4+, 5381VP usage, 5381

vaccine antigens, 146isotype responses, 3003

Schistosomiasisimmunity after treatment, 4984

SCID miceC. parvum, 3548, 4906IFN--y, 3548P. carinii

concurrent pneumovirus infection,1586

immunotherapy, 1641scrA gene

S. sobrinus, 2602

scrB geneS. sobrinus, 2602

SDZ 880.431macrophage gene expression, 3518

sea geneagr accessory gene regulator, 356

sec genesec mRNA, 1581sodium chloride, 1581

Secreted aspartyl proteinase genesC. albicans, 3240

Secretion systemstreptococci

oral, 3745Segmented filamentous bacteria

actin accumulation, 4001Sepsis

alpha-2-macroglobulinproteinase inhibitor, 5035

baboon model, 5035interleukin-1 receptor antagonist, 926K pneumoniae, 926minireview

animal models, 2741Septic shock

interleukin-6, 1496lipopolysaccharide-galactosamine model,

1496Septicemia

E. coli F1651-negative TnphoA mutant,836

SERA proteinP. falciparum

immunogenicity, 3933Seroprotective groups

B. burgdorferi, 4367Serpulina hyodysenteriae

lipoprotein geneouter membrane, 1136

outer membrane lipoprotein gene, 1136Serum passive immunizing activity

B. burgdorferi, 4696Sexual transmission

C. burnetii, 4188Shiga toxin

hemolytic uremic syndrome, 3886interleukin-1p, 3886

Shiga-like toxinmitomycin, 4510SLT-I and SLT-II

relative toxicities, 3392Shiga-like toxin I

B-subunit expression and localizationE. coli, 1098V. cholerae, 1098

Shigella flexnericellular cytoskeleton

subversion, 4941epithelial colonization, 4941fimbriae

type 1, 1687HeLa cell invasion, 4427IpaB

B-cell epitopes, 3825ipgD, 1707ipgF, 1707minireview, 4941mxi locus, 1707NF-iB DNA-binding activity, 4427OmpC, 3625phagocytic cells, 1687proteosome-lipopolysaccharide vaccines,

2390

INFECT. IMMUN.

SUBJECT INDEX xxxi

transformants, 1687vaccines

proteosome-lipopolysaccharide, 2390Shigella sonnei

proteosome-lipopolysaccharide vaccines,2390

vaccinesproteosome-lipopolysaccharide, 2390

Shigella spp.vaccines

conjugate, 36780-specific polysaccharides, 3678

Sialic acidmammalian cells, 898T. cruzi invasionenhancement, 898

Sialidase geneA. viscosus, 109

Siderophore production mutantB. bronchiseptica, 2698

Sigmented filamentous bacteriamucosal immune system

mice, 303Slime production

S. aureuscolonization, 4857virulence, 4857

S. epidermidisiron limitation, 4473

Sodium chloridesec gene expression

sec mRNA, 1581SpaAimmune responses, 1859S. sobrinus, 1859S. typhimurium

recombinant, 1859speB gene

inactivation, 3719S. pyogenes, 3719

Spirochetesbactenecins

antimicrobial activity, 3081Splenocytesp73 receptor

lipopolysaccharide, 1359pertussis toxin, 1359

Sprague-Dawley ratsmycoplasmosis

genital, 633spvB gene

S. dublin virulence plasmid, 5231ssb gene

B. abortus, 5339SspA gene

S. gordonii, 3199Staphylococcal enterotoxin A

mutationsearly transcribed region, 5421promoter spacer region, 5421

Staphylococcal enterotoxin Bleukocytes, 391lymphocytes, 391

Staphylococcal enterotoxin B deletion mu-tant proteins

concomitant loss of conformation andsuperantigenic activity, 2445

Staphylococcal enterotoxinslipopolysaccharide-potentiated toxicity

cytokine release, 5333major histocompatibility complex class

II, 5333

Staphylococcal enterotoxins Cnovel, 4254

Staphylococcal exotoxinsnatural killer cell cytotoxicity, 4013T-cell activation, 4013

Staphylococcipeptidoglycans, 4167tumor necrosis factor, 4167

Staphylococcus aureusagr, 356

virulence in murine arthritis model,3879

alpha-toxinkeratinocyte killing, 4972

capsular polysaccharidegrowth conditions, 1853type 8, 1853

enterotoxin BIL-10, 4937

enterotoxin type A internal deletion mu-tants

serological activity, 2059T-cell proliferation, 2059

enterotoxinsA, 5421B, 2445deletion mutant proteins, 2445emetic and T-cell-stimulatory activi-

ties, 3175lipopolysaccharide-potentiated toxic-

ity, 5333loss of conformation and superanti-

genic activity, 2445extracellular matrix-binding protein,

2479gamma-hemolysin locus, 768heat shock proteins

antibodies in endocarditis patients,1567

IFN-ynatural killer cells, 3117

leucocidin R, 580L-form, 1700osteomyelitis

rat model, 5225phagocytosis

iron, 1281monocyte-macrophage differentiation,

1281monocyte-macrophage stress re-

sponse, 1281phospholipase C

phosphatidylinositol specific, 5078sea, 356sec gene

sodium chloride, 1581sec mRNA, 1581slime productionphase variation, 4857

toxic shock syndrome toxin 1mutant, 793neutrophil inflammatory mediator re-

lease, 1055recombinant, 793

tumor necrosis factor alpha, 1700vaccines

capsular polysaccharide-P. aeruginosarecombinant exoprotein A conju-gates, 1023

xprglobal regulator of extracellular viru-

lence factors, 919phenotypic characterization, 919

Staphylococcus epidermidiscell envelope proteins

effect of growth conditions, 1743hypotension, 3342interleukin-1 receptor antagonist, 3342slime production

iron limitation, 4473transposon mutants

capsular polysaccharide/adhesin andslime deficient, 551

Staphylococcus hyicusexfoliative toxin

antigenicity, 2973Streptococcal superantigen pep M5

peripheral blood mononuclear cellscytokine release, 1194

Streptococcal surface protein antigen-chol-era toxin B subunit

intranasal immunization, 314mucosal immunity, 314

Streptococcialpha-hemolytic

C-polysaccharide phosphorylcholine-containing antigen, 3076

aminopeptidasesmutans group, 182

dental plaque, 3998group A

immunoglobulin G-binding proteins,1378, 3696

M protein, 2277M protein helper-T-cell epitope, 1062pharyngeal colonization, 2277survival in blood, 3696

group Banti-tumor necrosis factor alpha anti-

bodies, 227C5a-ase, 1421capsular polysaccharide, 2866cytokines, 227endothelial cell invasion, 478fibronectin, 2334host defense, 3761hyaluronidase, 3234neuraminidase, 3234neutrophil complement receptor inter-

actions, 2866neutrophil Fc receptor, 1415opacity variants, 3761phagocytosis, 2334protective antibodies, 4760respiratory epithelial cell invasion,

4835type III, 1415type III capsular polysaccharide, 478,

4835type Ia polysaccharide-tetanus toxoid

conjugate vaccine, 4760types Ia and Ib, 4760

immunoglobulin Al protease, 3998immunoglobulin G-binding proteins, 1378mutans

glucosyltransferase glucan-binding do-main, 2899

mutans groupaminopeptidases, 182glucosyltransferases, 4814

oralmodel secretion system, 3745

viridans groupcytokine induction, 5252extracellular products, 5252oral, 5252

VOL. 61, 1993

xxxii SUBJECT INDEX

Streptococcus agalactiaecapsular type polysaccharide, 1272virulence properties, 1272

Streptococcus defectivusadhesin

extracellular matrix, 4994Streptococcus downei

gtfS, 1246insoluble glucan synthesis

normal, 1246Streptococcus equisimilis

streptolysin 0, 2727Streptococcus gordoniiA. naeslundii coaggregation adhesin

gene, 981actinomyces, 3199Arthrobacter dextranase, 4375PK488 adhesin gene, 981salivary agglutinin, 3199SspA gene

inactivation, 3199Streptococcus mutansN-acetylglucosamine, 295adhesin P1

salivary agglutinin-binding domain,1547

adhesion, 4590collagen, 4119dentin, 4119

carbohydrate fermentation, 295collagen, 4119ftf and gtBC operon fusion strains

continuous culture, 1259glucosyltransferase

monoclonal antibody, 4689glucosyltransferases

monoclonal antibodies, 323gtf genes

caries induction, 3811gtfBDNA polymorphic region, 1563

gtfCDNA polymorphic region, 1563

immunizationantigen I/11-cholera toxin B subunit,

1964immunoglobulin A, 1964msm operon

cloning, 1121SA I/II

protein fragment, 4590sucrose-dependent adherence and aggre-

gationdecrease, 5021

surface protein antigensaliva-binding region, 4344

surface protein antigen alanine-rich re-peating region

antigenic epitopes, 1301wapA

inactivation, 5021Streptococcus parasanguis

adhesinfimbria associated, 1016

Streptococcus pneumoniaeattachment

cell wall, 1538cell wall

mediates attachment and cytopathol-ogy, 1538

cytopathologycell wall, 1538

endothelial cells, 1538

hemin utilizationvirulence, 5401

hydrogen peroxidetoxin, 4392

penicillin resistantmolecular epidemiology, 4382

pneumolysinimmunoreactive sites, 2822

Streptococcus pyogenescardiac muscle basal laminae

binding, 3259erythrogenic toxin A

neutrophil inflammatory mediator re-lease, 1055

glycosaminoglycan-binding protein, 3259mry-like gene, 5426speB

inactivation, 3719toxic shock syndrome, 3369toxic-shock-like syndrome, 5426virulenceMl, 5426M3, 5426

Streptococcus sobrinusN-acetylglucosamine, 295antigen fusions

E. coli heat-labile toxin subunit B,1004

S. typhimunium oral vaccine strains,1004

carbohydrate fermentation, 295gtfT, 2096scrA, 2602scrB, 2602surface protein antigen Aimmune responses, 1859S. typhimurium, 1859

Streptococcus suisepf, 3318epf*, 3318extracellular protein

repeats, 3318Streptolysin 0

S. equisimilis, 2727Streptomycin-treated mice

E. colicoccoid, 5029

Stress proteinsM. corti, 2596

Superoxide dismutaseD. immitis, 1157E. coli

resistance to phagocytic killing, 1442H. pylon, 5315

Surface antigen mutantsC. albicans, 3449

Surface protein antigenS. mutans, 1301

Syphiliscongenitalmodel, 3559pathology, 4743

rabbits, 4743

T cellsactivation

streptococcal M protein, 785C. neoformans glucuronoxylomannan,

1340CD4

L. pneumophila protease, 3416CD4+

dynamics, 1516H. capsulatum, 714host predisposition to infection, 1516

CD8+IFN--y, 3730L. major, 3730suppression of T-cell proliferation, 525

CD4+ CD8+ Thyl.2+listeriosis, 2703

cytotoxicmajor histocompatibility class I re-

stricted, 5374P. falciparum circumsporozoite pro-

tein, 5062E. coli hemolysin, 1715E. multilocularis protoscolices, 525-Y18

intestinal intraepithelial, 2154H. capsulatum, 714IFN--y, 2154, 3098L. major

lipophosphoglycan-deficient clone,5205

L. monocytogenes, 2154M protein, 785M. tuberculosis, 439multiple-antigen peptides

epitopes, 3064mycobacterial A60 antigen complex, 439mycobacterial heat shock proteinsHLA-DR molecules, 5294

P. falciparum, 4863merozoite proteins, 268

P. yoelii, 4863R. tsutsugamushi

protein antigens, 1674reactive arthritis, 4507S. aureus

enterotoxin type A internal deletionmutants, 2059

S. typhimurium, 3981AaroA AaroD mutants, 5374

T. brucei, 3098Thl

B. pertussis clearance, 399tuberculous pleuritis

guinea pig model, 142Y enterocolitica

urease P subunit, 4507Y pseudotuberculosis, 3922

T-cell clonesB. bovis specific

cytokine profiles, 3273cytokine production, 197L. donovani reactive

Thl- and Th2-like, 1069visceral disease, 1069

mycobacterium reactive, 197T. cnrzi, 3250

T-cell epitopesmultiple-antigen peptides, 3064pertussis toxinS4 subunit, 48, 56

S. muenchen flagellar antigen d, 1146T-cell lines

candidiasismurine disseminated, 3540protection, 3540

P. vinckei vinckei murine malaria, 1958T-cell receptorsCD4+

V,B, 5381S. mansoni, 5381

INFECT. IMMUN.

SUBJECT INDEX xxxiii

T-cell subsetsleishmaniasis, 2266TH1, 2266TH2, 2266

Tetanus toxinGG2EE macrophages, 3605lysozyme mRNA, 3605

Tetanus toxoidantibody responses, 4272B-cell responses, 4272cholera toxin

adjuvant, 4272oral vaccines

optimizing, 4272Thl cell epitopes

B. bovis Bb-1 protein, 236Thl-type responsesCandida specific, 4202candidiasis

vaginal, 4202Theileria parva

interleukin-2, 1486lymphocytes, 1486sporozoites, 1486tick salivary gland extract, 1486

T-helper cellsB. malayi, 1105

Thrombospondin-related anonymous pro-tein

antibody response, 3490P. falciparum, 3490

Tick salivary gland extractlymphocytes, 1486T. parva sporozoites, 1486

TnphoAE. coli K54 capsular polysaccharide

genesdisruption, 3578

TnphoA mutantsS. abortusovis, 1786

Toxic shock syndromeS. pyogenes, 3369

Toxic shock syndrome toxin 1inflammatory mediator release

neutrophils, 1055mutant, 793recombinant, 793

Toxic-shock-like syndromeS. pyogenes

miy-like gene, 5426Toxin A

C. difficile, 3988Toxins

B, 1082C. difficile, 1082

Toxoplasma gondiiacute infection

susceptibility, 2284antigens

bradyzoite specific, 1141IFN-y-treated macrophages, 1141immune responses, 2639immunostimulating complexes, 2639

chronic infectionprotective effect, 360susceptibility, 2284

cytokine mRNAcentral nervous system of SCID mice,

4038human immunodeficiency virus, 1596IFN-y, 5174immunization

antigens-cholera toxin, 2082

oral, 2082immunostimulating complexes, 2639indoleamine 2,3-dioxygenase, 1810macrophages, 4126

eicosanoids, 1432peritoneal, 1432

minireview, 1169monocytoid cells, 1596penetration, 1432phospholipases, 1432rat model, 360resistanceCD4+ and CD8+ lymphocytes, 5174IFN-y, 5174temporary, 5174

transforming growth factor ,, 4126tumor necrosis factor receptors, 4126

tpr gene productP. gingivalis, 4139

Transepithelial electrical resistanceE. coli

enteropathogenic, 2755TransferrinH. influenzae receptor, 4033N. meningitidis receptors, 751P. aeruginosa

cystic fibrosis, 5049proteolytic cleavage, 5049

Transforming growth factor yT. gondiimacrophages, 4126

Transposon mutantsS. epidermidis, 551

Trehalose 6,6'-dimycolate modelM. tuberculosis cord formation, 2296

Treponema denticolaouter sheath53-kDa surface antigen, 1694

surface antigen53 kDa, 1694outer sheath, 1694pore-forming properties, 1694

Treponema pallidumcongenital

model, 3559lipoprotein

17 kDa, 1202amphiphilicity, 1202macrophage activation, 1202

membrane immunogenlipid modification, 1202

opsonizationimmunoglobulin G, 781

pathology, 4743rabbits, 4743

Tnitnchomonas foetusimmunization

surface antigen TF1.7, 1385polymorphonuclear leukocyte killing,

2995TF1.7 surface antigen, 1385

Trypanosoma bruceiCD4- CD8- mice, 5129glycoproteins

invariant surface, 4540IFN-y, 3098T-cell responsiveness, 3098

Trypanosoma cruziadhesion molecule

82 kDa, stage specific, 3636metacyclic trypomastigotes, 3636

antigencarboxy-terminal domain, 4196

cDNA clone, 4196metacyclic trypomastigotes, 4196

CD4- CD8- mice, 5129invasion, 3636metacyclic trypomastigotes

surface antigen, 4196monoclonal antibody

FcyRII, Fc-yRIII specific, 4925sialic acidenhancement of invasion, 898mammalian cells, 898

T-cell clonesCD4+, 3250

trypomastigote decay-accelerating factorpartial cDNA clone, 3656

Trypomastigote decay-accelerating factorcDNA clone, 3656T. cruzi, 3656

TSA 417antigenic switching, 5394G. lamblia, 5394

Tuberculosispathogenesis, 2763

Tuberculous pleuritisT cells

guinea pig model, 142Tumor necrosis factor

bacterial clearancealterations, 3143

C5, 1474carrageenan-treated mice, 699endotoxic shock, 1474endotoxin induced, 699interleukin-1 receptor antagonist, 3342monocyte lipopolysaccharide responses,

3222mycobacterial defense, 3901P. falciparum, 4772pentoxifylline, 2737Plasmodium antigens, 2737platelet-activating factor antagonist, 699S. epidermidis, 3342staphylococci

peptidoglycans, 4167Tumor necrosis factor alpha

antibodiesgroup B streptococcal infection, 227

binding to bacteriahigh-affinity receptor, 830virulence, 830

E. coliimmunized mice, 3976

E. risticii, 4333endocarditis

subacute, 5413endotoxinmurine embryo fibroblasts, 1630

F. tularensis, 689immunized mice, 3976L. pneumophila

multiplication, 4980lipopolysaccharides, 1917myelopoiesis

lipopolysaccharide stimulated, 418neutralization, 689nitrogen oxide synthesis, 689polysaccharides, 1917R. prowazekii, 4317receptors, 5413S. aureus

L-form, 1700streptococcigroup B, 227

VOL. 61, 1993

xxxiv SUBJECT INDEX

Y pestis virulence, 23Tumor necrosis factor receptors

T. gondiimacrophages, 4126

Tumor necrosis factor-inducing proteinM. tuberculosis, 627

Ureaplasma urealyticumantigensmonoclonal antibodies, 2253serotype 4 specific, 2253

UreasesH. pylori

expression in E. coli, 2563P. mirabilis, 2570, 2748Y enterocolitica

13 subunit, 2498Urethral obstruction

bacteremia, 3422bacteriuria, 3422E. coli

"nonuropathogenic,', 3422pyelonephritis, 3422

Urinary tract infectionsinterleukin-8, 1307P. mirabilis urease, 2748

Uroepithelial cellsE. coli

lipopolysaccharides, 3304uvrA gene

B. abortus, 5339

VaccinationB. burgdorferiOspA, 2553

B. divergensexoantigens, 734

VaccinesA. pleuropneumoniae, 1682A. salmonicida

aromatic-dependent mutant, 2172antigens

S. mansoni, 146B. pertussis, 573carriers

alkaline phosphatase, 48cholera toxin B subunit, 48

E. colialpha-hemolysin, 1091

E. coli oligosaccharide-protein conju-gate, 5214

furunculosis, 2172H. influenzae type b

conjugate, 432suppression of antibody response, 432

L. amazonensisGP46/M-2 vaccine, 3351

liposomeshemagglutinin, 573pertussis toxoid, 573

oralcarriers, 48optimizing, 4272

Pnu-Imune, 2238proteosome-lipopolysaccharide, 2390pyelonephritis, 5214Q fever, 1251S. aureus capsular polysaccharide-P.

aeruginosa recombinant exoproteinA conjugates, 1023

S. dublinaroA 04-09 hybrid, 1211

aromatic-dependent hybrid, 1222S. flexneri, 2390S. mansoni

irradiated cercariae, 3003S. mansoni antigens, 146S. sonnei, 2390S. typhi Ty2la

Thai children, 1149Shigella spp., 3678streptococcigroup B types Ia and lb, 4760type Ia polysaccharide-tetanus toxoid

conjugate, 4760V. choleraeCVD 103-HgR, 729, 3994CVD110, 4462Peruvian adults, 3994

vaccinia viruses, 3351Vaccinia viruses

arthritisadjuvant, 4225

GP46/M-2 vaccine, 3351hsp60human, 4225

Leishmania infection, 3351Vacuolating cytotoxinH. pylori, 5008

Vacuolating toxinATPase inhibitors, 1427H. pylon, 1427HeLa cell response, 1427

Verotoxinimmunocompromise

gnotobiotic pigs, 2304Vibrio anguillarumAngR, 3228anguibactin

hyperproduction, 3228flagellar sheath antigen, 2434virulence locus

chromosomal, 2434Vibno cholerae

antibody-secreting-cell responses, 729hemagglutininmannose-fucose resistant, 3032mutant, 3032nucleotide sequence, 3032

immunoglobulin A, 5279pilinon-O1 strain, 5398

Shiga-like toxin IB-subunit expression and localization,

1098vaccinesCVD 103-HgR, 729, 3994CVD110, 4462Peruvian adults, 3994

Vibrio parahaemolyticusthermostable direct hemolysin

erythrocyte cation flux, 4326Vibrio vulnificus

capsule, 1611polysaccharide-protein conjugates

immunogenicity, 2053polysaccharides

capsular, 2053immunogenicity, 2053

virulenceeels, 1611

Vitamin Acholera toxinmucosal antibody response, 3952

Vitamin Dtuberculosis

cell-mediated hypersensitivity, 2116resistance, 2116

Vitamin D3-binding proteinmacrophages

inflammation-primed activation, 5388Vitronectin

P. canniibinding, 4302

Wangiella dernatitidisCDC genes, 2069yeast bud emergence, 2069

wapA geneinactivation, 5021S. mutans

sucrose-dependent adherence and ag-gregation, 5021

xprglobal regulator of extracellular viru-

lence factors, 919phenotypic characterization, 919S. aureus, 919

YadAY enterocolitica

opsonization by C3b, 3129yadA productY pseudotuberculosis

uptake, 3907, 3914Yersinia enterocolitica

adhesionmucin, 2340

ail, 1846antigen

arthritogenic cationic 19 kDa, 2498C57BL/6 mice

athymic T cell deficient, 2585euthymic, 2585nude, 2585

cytokinesgene expression, 2545release, 2545

enterotoxinheat stable, 764

lipopolysaccharidemodification by monocytes, 5261

mucin, 4131reactive arthritis, 4507serum killing, 1846urease

1 subunit, 4507T lymphocytes, 4507

urease 1 subunit, 2498YadA

prevention of opsonization by C3b,3129

Yersinia pestishemin, 32iron

inorganic, 32storage, 32

irp2deletion, 2717

low-calcium response, 13peptides, 13pigmentation loss, 2717virulence

IFN--y suppression, 23tumor necrosis factor alpha suppres-

INFECT. IMMUN.

SUBJECT INDEX xxxv

sion, 23Yersinia pseudotuberculosis

T-cell activation, 3922uptakeYadA dependent, 3907

YadA, 3907, 3914yadA4 product, 3907

Yersinia spp.enteropathogenic, 2513fibronectin binding, 2513

minireview, 3105outer membrane proteinYadA, 2513

YadAfibronectin binding, 2513

Yop proteinsnovel class, 71

YopB, 71YopD, 71Yops, 3105

Yopsminireview, 3105Yersinia spp., 3105

Zinc bindingcysteine dependent, 520G. lamblia membrane proteins, 520

Zinc metalloproteaseL. monocytogenes, 1576

VOL. 61, 1993

AMERICAN SOCIETY FOR MICROBIOLOGYAND

NATIONAL CENTER FOR INFECTIOUS DISEASES

1994 POSTDOCTORAL RESEARCHASSOCIATES PROGRAM

Up to ten associate positions will be awarded by the American Society for Microbiologyfor full-time research on infectious diseases which cause significant public health problems.Associates will perform research in residence at the National Center for Infectious Diseases(NCID) which is headquartered at the Centers for Disease Control and Prevention (CDC)in Atlanta, GA. In addition to Atlanta, NCID operates laboratories in Ft. Collins, CO,Anchorage, AK, and San Juan, Puerto Rico.

Eligible fields of study include: Bacterial and Mycotic Diseases, Viral and RickettsialInfections, Nosocomial Infections, HIV/AIDS, Vector-borne Infectious Diseases, SexuallyTransmitted Diseases, and Parasitic Diseases.

The program is intended for individuals who have held a doctorate degree (Ph.D., Sc.D.,or M.D.) since, but not earlier than, May 1, 1991. Exceptions may be made for thosewith more experience. The programn is open to both U.S. and foreign citizens. Qualifiedapplicants will receive consideration without regard to race, creed, color, age, sex, or

national origin. Diversity among associates is encouraged. The program provides an

annual stipend ranging from $28,000 to $33,000 and up to $2,000 for professionaldevelopment.

The application deadline is February 1, 1994. The Postdoctoral Research Program isadministered by the American Society for Microbiology. All inquiries regarding thisprogram should be addressed to: Coordinator, Postdoctoral Research Program, AmericanSociety for Microbiology, 1325 Massachusetts Avenue, N.W., Washington, D.C. 20005;(202) 942-9299.

ASM ODO/NOIDAMERICAN SOETY CENTERS FOR [ISEASE CONTROUNATIONAL CENTER FOR INFECTOUS DISEASESFOR MICROBIOLOOY AND PREVENTION

.

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