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Immunology Innate - Adaptive Immunity • Specificity • Memory • Tolerance
19

Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Jan 04, 2016

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Merilyn Greer
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Page 1: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunology

• Innate - Adaptive

Immunity• Specificity• Memory• Tolerance

Page 2: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Blood Components

• Erythrocytes• Lymph• Leukocytes

Macrophage

Lymphocytes• Cytokines• Plasma - Serum

Page 3: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Innate or

Nonspecific Immunity

Phagocytes

Adaptive or

Specific Immunity

B Lymphocytes

Antiserum

Page 4: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Cell-mediated immunity

• T Cells• Cytokines

Page 5: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Antibodies

• Antigen• Antibodies• Immunoglobulin• Humoral Immunity• Immunization

Page 6: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Antigens

• T Cell Receptors• Haptens• Antigenic

Determinants• Epitopes

Page 7: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

T Cells

• T Lymphocytes• T Cell Receptors• Major

Histocompatibility Complex

• Cytokines

Page 8: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

• Cytotoxic T Cells• Natural Killer Cells• Clonal Selection• Immune Tolerance• 1st, 2nd Response• Complement System • Sequentially interacting

proteins• Opsonization

Page 9: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunoglobulin

• Gamma Globulin• IgG• Heavy Chains• Light Chains• Memory Cells

Page 10: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Antigen Binding

• Constant Region• Variable Region• Gene

Rearrangement• 2 Antigen Binding

Sites per IgG

Page 11: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunoglobulins

• IgG - Smallest, Most Common, Transplacental

• IgA – Secretory• Plasma Cells• IgM - Largest• IgD• IgE - Allergies

IgA

IgM

Page 12: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunization

• Active - Passive Immunity

• Natural – Artificial Immunity

• Vaccine• Toxoid• Attenuated Strain• Passive Immunity

Page 13: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

New Vaccines

• Polyvalent• Genetically

Engineered Vaccines

• Subunit Vaccines• DNA Vaccine

Page 14: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immune Diseases

• Immediate Hypersensitivity

• Histamines• Anaphylactic Shock• Delayed-Type

Hypersensitivity• Contact Dermatitis• Autoimmune

Diseases

Tuberculin Test - Positive Result

Page 15: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunology Word ListImmunity

Specificity

Memory

Tolerance

Antigen

Antibody

Immunoglobulins

Humoral Immunity

Immunization

Cell-mediated Immunity

T Cells

Cytokines

Blood

Erythrocytes, Lymph

Leukocytes

Macrophage

Lymphocytes

Antigens

T Cell Receptors

Haptens

Antigenic Determinants

Epitopes

Nonspecific Immunity

Phagocytes

Specific Immunity

Page 16: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunology Word List 2B Lymphocytes

Immunoglobulins

Antiserum

IgG, Gamma Globulin

Heavy, Light Chains

Constant, Variable Regions

Gene Rearrangement

2 Antigen Binding Sites

Smallest, Transplacental

IgA, Secretory

IgM, IgD,

IgE Allergies

T Lymphocytes

T Cell Receptors

Major Histocompatibility Complex

Cytokines

Cytotoxic T Cells

Natural Killer Cells

Clonal Selection

Immune Tolerance

1st, 2nd Reponses

Complement System

Page 17: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Immunology Word List 3

Monoclonal Antibodies

Hybridoma

Myeloma

Antigen-Antibody Reactions

Neutralization

Precipitation

Agglutination

Immune Disease

Hypersensitivity

Autoimmune Diseases

Delayed-Type Hypersensitivity

Contact Dermatitis

Natural – Passive Immunity

Natural – Artificial Immunity

Immunization

Vaccine

Toxoid

Attenuated Strain

Passive Immunity

Genetically Engineered Vaccines

DNA Vaccines

Page 18: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Antigen-Antibody Reactions

• Neutralization• Precipitation• Agglutination

Page 19: Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.

Monoclonal Antibody

• Polyclonal Antibodies

• Hybridoma• Myeloma