Immunology and Serology Lecture # 2: Overview of Immunity

8/17/2019 Immunology and Serology Lecture # 2: Overview of Immunity

1/14

Fvhrvlhw fj LeeucltyMry`c Elkg`hn C. M`nuchs, ]EY


2/14

_g`t ls Leeuclty6

L[ Nhk ! Fvhrvlhw fj Leeuclty

• ]hslst`ckh tf lcjhktlfus `ohcts, jfrhloc p`rtlknhs, tfxlcs, nlvlco khnns, `ci

k`ckhr (Mry`ct)

• Kfciltlfc fj mhlco rhslst`ct tf lcjhktlfc ([thvhcs)


3/14

Yy"hs fj Leeuclty


0. C@YX]@N LEEXCLY\ (Lcc`th, Cfcsphkljlk, Cfc`i`ptlvh)• ]hslst`ckh fj lcjhktlfc my eh`cs fj cfre`nny prhshct mfiy jucktlfcs

• Rrhshct `t mlrtg• f prlfr hxpfsurh ls rh!ulrhi• ]hspfcsh ifhs cft kg`coh "ltg sumsh!uhct hxpfsurhs

=. @I@RYLZ LEEXCLY\ (!phkljlk, @k"#l$hi)

• ]hslst`ckh `k!ulrhi `s ` rhsunt fj prlfr hxpfsurh "ltg ` jfrhlocsumst`ckh

• ]hslst`ckh my sphkljlklty jfr h`kg lcilvliu`n p`tgfohc• ]hehemhrs prlfr hxpfsurh• #ckrh`shi rhspfcsh upfc rhph`thi hxpfsurh


4/14

Yy"hs fj Leeuclty


0. C@YX]@N LEEXCLY\ (Lcc`th, Cfcsphkljlk, Cfc`i`ptlvh)• ]hslst`ckh fj lcjhktlfc my eh`cs fj cfre`nny prhshct mfiy jucktlfcs

• Rrhshct `t mlrtg• f prlfr hxpfsurh ls rh!ulrhi• ]hspfcsh ifhs cft kg`coh "ltg sumsh!uhct hxpfsurhs

=. @I@RYLZ LEEXCLY\ (!phkljlk, @k"#l$hi)

• ]hslst`ckh `k!ulrhi `s ` rhsunt fj prlfr hxpfsurh "ltg ` jfrhlocsumst`ckh

• ]hslst`ckh my sphkljlklty jfr h`kg lcilvliu`n p`tgfohc• ]hehemhrs prlfr hxpfsurh• #ckrh`shi rhspfcsh upfc rhph`thi hxpfsurh


5/14

C`tur`n Leeuclty


• %th$c`& Ihjhcsh !'sth

• Lcth$c`& Ihjhcsh !'sth


6/14

C`tur`n Leeuclty


0. Y]C@N I*C! !\!YE (*l$st Nlch fj Ihjhcsh)

• Xc+$fhc slc `ci #kfs`& h+$`ch s#$j`khs

• !hk$htlfcs $ ilskfur`ohs elkrfml`n orf"tg %ukus &`ktlk `kli (s"h`t) $ e`lct`lcs s'lc `t p *+

[hmue (shm`khfus on`cis) $ s`eh " n`ktlk `kli -`r"`x (khruehc)


7/14

C`tur`n Leeuclty


0. Y]C@N I*C! !\!YE (*l$st Nlch fj Ihjhcsh)

• -fi' hk`clss .hr`tlcl/`tlfc fj tgh upphr n`yhr fj tgh s'lc Kfcst`ct rhch"`n fj hpltghnl`n khnns %ftlfc fj klnl` 2rlch $ jnusglco `ktlfc0 snlogt `klilty &`ktlk `kli lc jhe`nh ohclt`n tr`kt $ p fj *= ;klilty fj stfe`kg (Kn) $ p 9 8*= ;n'`nlclty fj tgh jnulis fj tgh :#? &ysf/yeh (th`rs `ci s`nlv`) $ `tt`k's `ci ihstrfys khnn "`nn

fj elkrffro`clses, hsphkl`nny or`e7pfsltlvh m`kthrl`

• Cf$`& j&f$` $ glcihrs phchtr`tlfc fj elkrffro`clses (kfephtltlvh

hxknuslfc)


8/14

C`tur`n Leeuclty


=. LCY]C@N I*C! !\!YE (!hkfci Nlch fj Ihjhcsh)

• R`/fk'tlk kh&&s $ e`


9/14

#$`"tlvh Leeuclty


• Yl$i Nlch fj Ihjhcsh

ERCCY!

0. N'pfk'ths $ e`


10/14

#$`"tlvh Leeuclty


@Y;]L! * @I@RYLZ ]!RC!

0. 2#f$`&9Ehil`thi L#clt'

=. h&&9Ehil`thi L#clt'

Ehk`cls %hil`thi my `ctlmfiy

h&& t'ph M nyepgfkyths

Efih fj `ktlfc ;ctlmfilhs lc shrue

R#$pfsh Rrle`ry ihjhcsh `o`lcst m`kthrl`n lcjhktlfc

Ehk`cls %hil`thi my khnn

h&& t'ph ? nyepgfkyths

Efih fj `ktlfc 4lrhkt khnn7tf7khnn kfct`kt fr sfnumnh prfiukts

shkrhthi my khnnsR#$pfsh 4hjhcsh `o`lcst vlr`n `ci juco`n lcjhktlfcs,

lctr`khnnun`r fro`clse, tuefr `ctlohcs, `cior`jt rh


11/14

#$`"tlvh Leeuclty


Y\R! * 2XE]@N9EIL@YI LEEXCLY\

0. @ktlvh L#clt'

C`tur`n @ktlvh

@rtljlkl`n @ktlvh

Efih fj `k"#lsltlfc #cjhktlfc

@ctl+fi' p$fi#khi +' fst 1hs

I#$`tlfc fj l#ch $hspfcsh &fcoEfih fj `k"#lsltlfc #cjhktlfc

Efih fj `k"#lsltlfc >`kklc`tlfc

@ctl+fi' p$fi#khi +' fst 1hs

I#$`tlfc fj l#ch $hspfcsh &fco (leeucfkfephct gfst)

Efih fj `k"#lsltlfc >`kklc`tlfc


12/14

#$`"tlvh Leeuclty


Y\R! * 2XE]@N9EIL@YI LEEXCLY\

=. R`sslvh L#clt'

C`tur`n R`sslvh

@rtljlkl`n R`sslvh

Efih fj `k"#lsltlfc #c vlvf tr`csjhr fj `ctlmfilhs mye`thrc`n klrkun`tlfc lc uthrf0

kfnfstrue@ctl+fi' p$fi#khi +' fst f

I#$`tlfc fj l#ch $hspfcsh [gfrt

Efih fj `k"#lsltlfc #cjuslfc fj shrue fr pn`se`

@ctl+fi' p$fi#khi +' fst f

I#$`tlfc fj l#ch $hspfcsh [gfrt


13/14

[uee`ry fj Leeuclty


*l$st Nlch fj Ihjhcsh

(lcc`thcfcsphkljlkc`tur`n leeuclty)

!hkfci Nlch fj Ihjhcsh

(lcc`thcfcsphkljlkc`tur`n leeuclty)

Yl$i Nlch fj Ihjhcsh

(ì`ptlvhsphkljlk`k!ulrhi leeuclty)

• #ct`ktucmrf'hc s'lc `ci

eukfus ehemr`chs

7 shkrhtlfcs

7 strukturhs (g`lrs, klnl`,

hpltghnl`n khnn n`yhr)

• %hkg`clk`n ̀ ktlfc

• fre ǹ jnfr` (cfre`n

elkrfmlft`)

• Rgòfkytlk khnns

7 or`cunfkyths

(chutrf, hfslcf, m`sf)

7 efcfkyth7e`krfpgòh

7 ;RKs

• uefr ǹ (jnuli) j`ktfrs

7 kfepnhehct

7 nysf/yeh

7 lcthrjhrfc

7 `kuth7pg`sh rh`kt`cts

• &yepgfkyths (khnnun`r)

7 ? nyepgfkyth (? ghnphr 8, ? ghnphr 5,

? kytftfxlk, ? rhoun`tfry)

7 M nyepgfkyth

(pn`se` khnn, ehefry khnn)

• uefr`n j`ktfrs

7 `ctlmfiy

7 kytf'lch


14/14

Immunology and Serology Lecture # 2: Overview of Immunity

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