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MIT Open Access Articles Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid Surfaces The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation: Smith, Rachel Soo Hoo, Bader, Christoph, Sharma, Sunanda, Kolb, Dominik, Tang, Tzu# Chieh et al. 2019. "Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid Surfaces." Advanced Functional Materials, 30 (7). As Published: http://dx.doi.org/10.1002/adfm.201907401 Publisher: Wiley Persistent URL: https://hdl.handle.net/1721.1/140947 Version: Author's final manuscript: final author's manuscript post peer review, without publisher's formatting or copy editing Terms of use: Creative Commons Attribution-Noncommercial-Share Alike
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Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid Surfaces

May 29, 2023

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Hiep Nguyen

Living cells host a diverse and extensive repertoire of processes that, if functionalized, would have extraordinary value as synthetic tools.[1–4] Yet, beyond the confines of industrial bioreactors, there are limited examples of how bioengineers can utilize the functionalities of living cells reliably, at macroscopic length scales, or outside of cells’ natural environments. At present, the field of biohybrid materials combines living and non-living components with the objective of harnessing the capabilities of biological systems within structural materials

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Living cells integrated into biohybrid walls,[6–9] biohybrid fibers,[10–12] and bio-bots[13–16] provide early examples of how such fabrications can enable a new class of uniquely responsive and multifunctional products.