Radiation Protection Research From FP6 to FP7 Neale Kelly
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Radiation Protection Research
From FP6 to FP7
Neale Kelly
Topic %Radiobiology 46Epidemiology 25
Medical uses 7Risk and emergency
management15
Radioecology and
environmental protection
5
Dosimetry 0.6Education and training 1
Other topics
Risks at low and
protracted doses
Distribution of FP6 budget
Trends between FP5 and FP6
FP5 % FP6 %
Risks at low doses 47 71
Medical uses and natural radiation
12 7
Risk and emergency management
18 15
Radioecology 10 5
Dosimetry 13 0.6
Radiobiology – Integrated Projects
RISC-RAD (16 M€) – multi-disciplinary approach to better understanding of mechanisms and quantification of risk
DNA damage and repair, genomic instability, mechanisms of tumorigenesis, genetic susceptibility, individual sensitivity, modelling
NOTE (11 M€) – non targeted effects of radiationmechanisms underlying NTE, effect on cancer risk at low doses, influence on non-cancer disease, etcimplications for radiation protection
Radiobiology - STREPS
ERA-PRO (0.4 M€) – database of animal radiobiology studies in EU, US and JAP since 1960
GENRISK-T (4.4 M€) - genetic influence on the risk of radiation induced thyroid cancer
GENEPI-ENTB2 (1.5 M€) - tissue bank for use in studies of the genetic determinants of individual radiosensitivity
GENEPI-lowRT (1.8 M€) – influence of genetic factors on individual radiosensitivity
Epidemiology – Integrated Project
SOUL - Southern Urals cohorts (12 M€)Cohorts
o Mayak (external, plutonium)o Techa River (external, strontium)
Effectso cancer incidenceo cancer mortalityo non cancer diseases
Collaborationo RF, US and EUo Opportunities to broaden
Epidemiology - STREPS
ALPHA RISK – exposures to α radiation (4.4 M€)Cohorts
o U minerso domestic radono fuel cycle workers (U, Pu)
GENE RAD RISK – role of genetic susceptibility and radiation exposure in breast cancer (2 M€)
RACE – cardiovascular disease in breast cancer patients treated with radiotherapy (1.4 M€)
Medical Uses of Radiation
CT (3.1 M€) – optimisation and justification of CT for a wide range of clinical applications including cardiac, interventional and paediatric
good practice guidelines
SENTINEL (0.7 M€) – optimisation and justification of new and emerging imaging techniques (excluding CT) in diagnostic and interventional radiology
physical and clinical image quality criteriagood practice guidelines
Radioecology and Protection of the Environment
ERICA (3.9 M€) – integrated approach to assessing and managing the impact of radiation on the environment
PROTECT (0.6 M€) – evaluation of the merits and practicability of different approaches for regulating protection of the environment
FUTURAE (0.7 M€) – evaluation of potential for establishing deeper and sustainable integration of European research on radioecology, in particular through a Network of Excellence
Emergency Management
EURANOS (14 M€) – emergency management and rehabilitation strategies
handbooks on countermeasurs for agricultural and inhabited areasimproved decision support system (RODOS)demonstration projectsstrategies for and guidance on rehabilitationuser driven
TMT Handbook (0.7 M€) - monitoring and treatment of populations exposed to malevolent uses or radiation or radioacative materials
Protection of the Workplace
CONRAD (0.3 M€) – network to maintain and enhance European competence in radiation protection dosimetry
analysis of options for achieving deeper and sustainable integration of European researchworking groups on computational dosimetry, internal dosimetry, complex mixed radiation fields and occupational exposure in medical radiology
Further information
links to reports of completed projects in FP5http://www.cordis.lu/fp5-euratom/src/lib_finalreports.htm
links to ongoing projects in FP6http://europa.eu.int/comm/research/energy/fi/fi_pubs/article_1
186_en.htm
G N Kelly, EC, DG Research [email protected]
7th Framework Programme (EURATOM) (2007-2011/13)
Nuclear FusionNuclear Fission and Radiation Protection
management of radioactive wastereactor systemsradiation protectioninfrastructureshuman resources and training
Underlying Principles
Continuity with the FP6Simplification
reduce “red tape”IPRfunding schemesreporting
Content – Radiation Protection
Quantification of risks for low and protracted exposures
epidemiological studiesunderstanding mechanisms
Medical uses of radiationenhance their safety and efficacy (in diagnosis and therapy) through new methodological and technological developments achieve balance between benefits and risks
Content – Radiation Protection (cont’d)
Emergency management and rehabilitationimprove coherence through development of common tools and strategiesdemonstrate efficacy in operational environments
Malevolent usesComplementary to EC Security programme
Other topics (dosimetry, radioecology, natural…)more effective integration of national research activities
Budgetary Resources
FP6190 M€ for 4 years (≈ 50 M€ per year)
o RP 50 M€
FP7 – initial Commission proposal394 M€ for 5 years (≈ 80 M€ per year)
o single budget – no subdivision for RP
FP7 – revised Commission proposal287 M€ for 5 years (≈ 60 M€ per year)
Work Programmes and Calls
WP under preparationadoption by Commission in December (subject to timely approval of FP and SP by Council and Parliament)
First call in late ’06 or early ’07First deadline – probably second quarter of ’07WP to be updated annually
Funding Schemes
Collaborative ProjectsNetworks of ExcellenceCoordination and Support ActionsActions to promote and develop human resources and mobility
Funding Schemes (cont’d)
Collaborative projects
Details still under discussion between COM/Council/EP
Maximum of 50% contribution likely to the be the general rule with some exceptions Additional Cost Model will probably disappear
Funding Schemes (cont’d)
Reimbursement at 100%Coordination and support actionsTraining, career developmentFrontier research (ERC)
Draft Work Programme 2007
Undergoing inter-service consultation within the CommissionSent to Members of CCE Fission Committee and will be informally discussed in early NovemberTo be finalised in December subject to approval of Framework and Specific ProgrammesContent/Timing – influenced, inter alia, by status of and expected outcome of ongoing from FP6 projectsIndicative budget – 52 M€
Quantification of risk for low and protracted exposures
Non cancer effects, especially cardio- and cerebro-vascular diseases
One or more Collaborative Project/s
Feasibility of establishing a prospective cohort of medically exposed children
A Support Action
Medical uses of radiation in diagnosis and therapy
Reducing patient exposureAcquisition of key information for sound and scientifically based judgements on use of existing and emerging imaging techniquesQuality criteriaSynergy through networkingBroadly applicable methodologies for assessing and reducing doses to peripheral tissues in therapy
One or more Collaborative Project/s and/or Coordination Action/s
Emergency Management and Rehabilitation
Optimising the design of monitoring systems
o Develop methodology for optimising the design of monitoring systems at national or regional levels to better exploit state of the art decision support systems for emergency management (ie, to achieve more timely and better quality decisions)
A collaborative project
Supporting infrastructure
Data bases and tissue banksDesign, refurbish, construct, operate and/or provide access to key data-bases or tissue banks for use in radiation protection research
One or more Collaborative Project/Coordination Action or Support Action
Radiobiology infrastructuresAssess status of radiobiology infrastructures in Europe and evaluate adequacy for low-dose risk research
A Support Action
Actions supporting programme implementation and other activities
Dissemination of programme results
Contributing to strategic objectives, notably ERA
Preparation of future activities
One or more Support Actions
Work Programme 2008 and beyond?
WP 2008expected to focus on low dose risk research –radiobiology and epidemiology
WP 2009as WP 2008 plus further research on medical uses of radiationConsideration to be given to NoE in fields of dosimetryand radioecology subject to outcome of FP6 projects
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