ENDO 2012: The 94th Annual Meeting of The Endocrine Society

P R O G R A M H I G H L I G H T S

Early Registration Deadline: May 1, 2012

Housing Request Deadline: May 30, 2012

www.endo-society.org/endo2012

Where the World of Endocrinology Meets

Dear Colleague,

We are pleased to invite you to attend ENDO. The plenary and symposia offerings at ENDO 2012 are not to be missed. We are especially proud of the programs at this year’s meeting that address all three of our constituencies.

This year, the new Master Clinicians Sessions will expand to three offerings— pituitary, type 1 diabetes, and precocious puberty. The “Year In” sessions will highlight sex differences in endocrine research and obesity-cancer connections. Six innovative symposia—topics ranging from imaging and interventional radiology in the evaluation of endocrine disorders, to nuclear receptors and inflammation, to diabetes and cognitive function—will appeal to wide audiences. Whether you are a researcher, in training, or an established practitioner, ENDO offers educational programs specifically tailored to your needs.

With the broad representation of researchers and practitioners in endocrinology attending ENDO, our meeting continues to offer unparalleled opportunities for networking and collaboration. Make plans to visit ENDOExpo, where poster communities are an excellent venue for exchange, and ENDO Connect, where small tables with wireless access facilitate scientific discussions.

ENDO also offers attendees opportunities to participate in light-hearted events, including cooking demonstrations and the team-based ENDO Trivia Cup Challenge.

We hope to see you in Houston!

Lynnette K Nieman, MDNICHD/NIH

Chair, ENDO 2012

Joel K Elmquist, DVM, PhDUniv of Texas SW Med Ctr

Basic Science Chair, ENDO 2012

Anthony L McCall, MD, PhDUniv of Virginia Sch of MedClinical Chair, ENDO 2012

W e L c O M eW e L c O M e

THe eNDOcRINe SOcIeTY’S94TH ANNUAL MEETING & EXPO

June 23–26, 2012 | Houston, Texas

www.endo-society.org/endo2012 | 1

The Society is excited to bring the world’s largest endocri-nology meeting to the fourth-largest city in the United States, Houston, Texas. Houston is home to 17 of the most renowned medical centers in the United States, including the Texas Medical Center—the world’s largest medical complex and a thriving center for scientific and medical research.

Houston is a cosmopolitan city that offers something for everyone—including world-class museums and a Theater District second only to New York City. In addition, Houston has one of the best culinary scenes in the country. There are more than 8,000 restaurants in the Houston area, with dining choices that represent more than 35 regions and countries.

To assist our international travelers, the Houston airport is offering a dedicated passport control line exclusively for ENDO attendees. International attendees can also take advantage of tax-free shopping while visiting Houston. To learn more, visit www.taxfreetexas.com.

Visit the ENDO 2012 site for more information and short videos on Houston in 10 languages.

H O U S T O N

2 | For up-to-date meeting information, visit www.endo-society.org/endo2012

P R e - c O N f e R e N c e e v e N T S

Diabetes Diagnosis & Management 2012Strategies for Difficult clinical cases

Registration Fees(Includes continental breakfast and lunch)

Member or ENS Member .........$55Non-Member ...........................$85In-Training (member or non-member) ...................$45

Program ChairsKieren J Mather, MD, Indiana UnivGraham T McMahon, MD, Brigham and Women’s HospCarol H Wysham, MD, Univ of Washington Sch of Med

Choosing the Best Treatment OptionsThis full-day workshop prior to ENDO 2012 invites expert faculty to focus on current advanced practice challenges and provides a state-of-the-art update for all who treat difficult diabetes cases. This interactive workshop utilizes Audience Response technology throughout the sessions to examine case vignettes and poll the audience on treatment options.

Program Highlightsn Discussion of the latest treatment

guidelines from The Endocrine Society and the American Diabetes Association

n Symposium on the microvascular complications of diabetes—neuropathy, retinopathy, and nephropathy

n Multiple Meet-the-Professor sessions

n Hands-on workshop: managing insulin pump therapy and troubleshooting pump problems

Agenda

9:00 – 9:30 AMRegistration & Continental Breakfast

9:30 – 9:45 AMIntroduction

SYMPOSIUM I: TREATMENT OF HYPERGLYCEMIA & T2DM

9:45 – 11:30 AM

New ADA Treatment Guidelines

Incretins & Insulin in Type 1 & Type 2 Diabetes

Bariatric Surgery: Evaluation Before & Management After

11:30 AM – 12:00 PMPanel Discussion

12:00 – 1:00 PMLunch

FRIDAY, JUNE 22 | George R Brown Convention Center

9:30 AM – 5:30 PM

Content as of January 20, 2012 www.endo-society.org/endo2012 | 3


2012 Corporate Liaison Board ForumThe CLB Forum highlights the collabo-ration among industry, academia, and health care agencies, both government and non-government, in approaches to the treatment of endocrine disorders.

FRIDAY, JUNE 22

6:30 – 9:30 PMHilton Americas-Houston

Diabetes & Cardiovascular Risk: Is Personalized Medicine the Answer?

Program Director: Barbara Lippe, MD, Genentech, Inc.

Program Overview, Welcome, & Introduction: Barbara Lippe, MD, Genentech, Inc.

TOPiC AReAs:

Genetic and Metabolomic Prediction of Type 2 DiabetesJose C Florez, MD, PhD, Harvard Med Sch

Current Personalized Medicine Approaches in DiabetesSamuel Dagogo-Jack, MD, Univ of Tennessee Hlth Sci Ctr

Personalized Medicine in CV—DM January 20, 2012Luther T Clark, MD, FACC, Global Director for Scientific Affairs for Atherosclerosis, Merck & Co., Inc.

Health Care Disparities in the USCara James, PhD, Kaiser Family Fdn

Panel DiscussionThis session is not eligible for CME credit.

1:00 – 1:45 PM

Breakouts Round 1Meet-the-Professor Sessions & Hands-on Workshopsn Management of Hypertriglyceridemia/low

HDLn Continuous Glucose Monitoringn Sleep & Diabetesn Gestational Diabetesn Behavior Change in Diabetesn Hands-on Insulin Pump Workshopn Hands-on Fundoscopy Workshop

1:45 – 1:50 PMBreak

1:50 – 2:40 PM

Breakouts Round 2Repeat Meet-the-Professor Workshops

2:40 – 2:55 PMBreak

SYMPOSIUM II: MICROVASCULAR COMPLICATIONS

2:55 – 4:40 PM

Diagnosis & Management of Diabetic Neuropathy

Diagnosis & Management of Diabetic Retinopathy

Nephropathy & Stage 3 CKD

4:40 – 5:10 PMPanel Discussion

5:10 – 5:30 PMFollow-up & Closing


Registration limited to 90 participants

Registration Fees (Includes lunch)

Member or ENS Member ........ $405Non-Member .......................... $475In-Training (member or non-member) .................. $285

Registration Prerequisite: The registrant must currently be performing diagnostic thyroid ultrasound and ultrasound-guided fine-needle aspiration biopsies routinely in his/her prac-tice. This 5.5-hour course is designed to in-troduce participants to the use of ultrasound for examination of the cervical lymph nodes and parathyroid adenomas. There will be four didactic lectures and one hands-on session with participation by patients with thyroid cancer and hyperparathyroidism.

OBJECTIVESUpon completion of this educational activity, participants will be able to:n Review indications for ultrasound exami-

nation of cervical lymph nodes in thyroid cancer patients

n Demonstrate the imaging procedure and characteristics of benign and malignant lymph nodes

n Discuss and illustrate the imaging characteristics of parathyroid adenomas

n Practice slide preparation and cytology specimen interpretation

Hands-on Thyroid Ultrasound Workshops

AGENDA

8:00 – 8:05 AMWelcome & IntroductionSusan J Mandel, MD, MPH, Univ of Pennsylvania Sch of Med

8:05 – 8:30 AMMetastatic Lymph Nodes: Why They Matter

8:30 – 9:15 AMUltrasound Evaluation of Lymph Nodes

9:15 – 9:40 AMParathyroid Ultrasound

9:40 – 10:00 AMCytology: Preparation & Interpretation

10:00 – 10:30 AMQ & A

10:30 AM – 1:30 PMPracticum: Diagnostic Thyroid Ultrasoundn Ultrasound didactic demonstration session

on metastatic thyroid cancer lymph nodes and parathyroid adenomas

n Hands-on session in ultrasound tech-nique to image the post-operative neck, ultrasound fine-needle aspiration biopsy technique using a curvilinear probe, and cytology slide preparation and onsite analysis


FRIDAY, JUNE 22 | George R Brown Convention Center

8:00 AM – 1:30 PM

Advanced Hands-on Thyroid Ultrasound Workshop


Registration limited to 85 participants

Registration Fees (Includes snacks)

Member or ENS Member .................$375Non-Member ...................................$445In-Training (member or non-member) ..$260

This 5-hour course is designed to introduce participants to the use of ultrasound in the diagnosis of thyroid nodules and perform ultrasound-guided fine-needle aspirations. There will be four didactic lectures and one hands-on session.

OBJECTIVESUpon completion of this educational activity, participants will be able to:n Review the technology of ultrasound imagingn Demonstrate the imaging characteristics

of thyroid nodules and diffuse thyroid disorders

n Perform diagnostic thyroid ultrasound imaging and identify normal neck anatomy

n Perform ultrasound-guided fine-needle aspiration biopsies using a simulated model

n Practice slide preparation and cytology specimen interpretation

1:30 – 6:30 PM

Introductory Hands-on Thyroid Ultrasound Workshop

AGENDA

1:30 – 1:35 PMWelcome & IntroductionSusan J Mandel, MD, MPH Univ of Pennsylvania Sch of Med

1:35 – 2:00 PMPhysics of Ultrasound

2:00 – 2:45 PMUltrasound of Thyroid Nodules

2:45 – 3:00 PM Break

3:00 – 3:25 PMUltrasound of Diffuse Thyroid Disorders

3:25 – 3:45 PMUltrasound-Guided Fine-Needle Aspiration

3:45 – 6:30 PMPracticum: Ultrasound-Guided Fine-Needle Aspirationn Ultrasound Technique for Diagnostic

Thyroid Evaluationn Ultrasound Fine-Needle Aspiration

Biopsy Techniques


Registration Fees: Members or ENS Members: $210, Non-Members: $335 (Includes dinner and the online-only Lipids & Obesity MOC: A Self-Assessment Module)

Faculty Presenters: Maria L Collazo-Clavell, MD, Mayo Clin; Lisa R Tannock, MD, Univ of Kentucky

This Live Learning Session allows participants to review Lipids & Obesity MOC: A Self-Assessment Module, an online case-based tool containing 25 practice-related questions on lipid disorders and obesity. The authors, Drs Collazo-Clavell and Tannock, will lead participants through the questions of the module, using audience response key-cards to poll participants’ answers and discussing the key points of each case. Participants then receive access to the online module, which has been approved by the ABIM for 10 MOC points toward self-assessment of medical knowledge.

Lipids & Obesity MOC Live Learning SessionSATURDAY, JUNE 23 | George R Brown Convention Center | 6:00 – 9:00 PM

10 MOC

Points


Endocrine Trainee Day—Class of 2012FRIDAY, JUNE 22 | George R Brown Convention Center

8:00 AM – 5:30 PMThe 6th Annual Endocrine Trainee Day is an opportunity for postdoctoral fellows, clinical fellows, and medical and graduate students to interact with their peers and be inspired by the recognized experts in the endocrine community.

This popular event offers programming tailored for basic science and clinical students and fel-lows, including plenary lectures on translational endocrine research and two concurrent tracks of educational sessions.

Highlights of the program include advice on career choices from some of endocrinology’s most suc-cessful scientists and clinicians, as well as their perspectives on striking a healthy balance between career and personal life. General registration will open on March 2, 2012, and is on a first-come, first served-basis, until space is filled.

ADvANcING S c I e N c eeNRIcHINGc A R e e R S


12:00 – 1:00 PMLunch & Poster Time

1:00 – 2:00 PMSecond Keynote Address: HR in Prostate Cancer

SESSION 2: COMPLICATIONS & RISKS OF ADT & HRT IN PROSTATE & BREAST CANCER

2:00 – 4:00 PM

ADT Complications

HRT: Re-evaluation of the Effects of HRT

Role of Stem Cells in Prostate Cancer Risk

Effect of Parity & Breast Cancer Risk

Discussion

4:00 – 6:00 PMPoster Time & Cash Bar

9:00 AM

Welcome & IntroductionReflections on the contributions of the late Jonathan Li, PhD, founding Editor of Hormones and Cancer

9:05 AMOpening Keynote Address: Mechanisms of Resistance in Breast Cancer

SESSION 1: NEw INSIGHTS INTO BREAST & PROSTATE CANCER

10:00 – 12:00 PM

Whole Genome Sequencing from Breast Cancer Aromatase Trial

Mechanisms of AR Action in Castrate Resistant Prostate Cancer

Targeting Compensatory MAPK Signaling in Castrate Resistant Prostate Cancer

Discussion

This forum brings together global experts on endocrine mechanisms of breast and prostate cancer development and treatment to discuss and help develop tomorrow’s cure.

New! Hormones and Cancer ForumFRIDAY, JUNE 22 | George R Brown Convention Center

9:00 AM – 6:00 PM


ENDOExpo—a great place for you to view posters, interact with exhibitors, and network.

Get the information you need... Exhibitors at ENDOExpo cover more than 70 different product categories and can give you the information you need on latest products in the field.

Gain even more insight by attending an ENDOExpo Theater demonstration on the latest products.

Find colleagues and collaborators... With 2,600 posters, there is plenty of great science to talk about, and plenty of eager presenters to discuss it with.

Looking for a place to meet? Plan to meet your colleagues at ENDO Connect, where you can also check your email and update your meeting itinerary.

Take the break you need... Free coffee is provided every morning and afternoon to enjoy while previewing posters and visiting the exhibits.

Or receive a massage from our onsite therapists at the Relaxation Station.

Get delicious advice from top chefs... Part of The Hormone Foundation’s Cooking for Pleasure, Healthy for Life series, these cooking demonstrations will be held daily at the ENDOExpo.

Learn practical tips to improve your patients’ nutrition and general well-being.

Learn more about what ENDOExpo 2012

has to offer at www.endo-society.org/endo2012

See you at the Expo!

Add Extra Sizzle to ENDO 2012

Visit theENDOExpoJune 23–26, 2012 • Houston, Texas


P L e N A R Y S e S S I O N S

SATURDAY, JUNE 23

7:45 – 9:15 AM

Presidential Plenary LectureThe National Institute of Child Health & Human Development: 50 Years Old & Looking to the FutureAlan E Guttmacher, MD, National Inst of Child Hlth & Hum Devel

Presidential Plenary LectureNext Generation Human Genetics: A Path to New BiologyJoel N Hirschhorn, MD, PhD, Children’s Hosp

5:30 – 6:30 PM

Clinical Investigator Award LectureCellular Mechanisms of Insulin Resistance: Implications for Obesity, Lipodystrophy, Type 2 Diabetes, & Metabolic SyndromeGerald I Shulman, MD, PhD, Yale Univ Sch of Med/Howard Hughes Med Inst

Transcriptional Control of Adipose Biology & Energy Homeostasis: Toward Novel TherapeuticsBruce Spiegelman, PhD, Dana Farber Cancer Inst/Harvard Med Sch

SUNDAY, JUNE 24

8:00 – 9:15 AM

Fukushima Daiichi Nuclear Disaster & Radiation Health Risk ManagementShunichi Yamashita, MD, DSC, Nagasaki Univ (Japan)

Genetic Disorders of Thyroid Hormone Synthesis & ActionV Krishna K Chatterjee, MD, Univ of Cambridge/ Addenbrooke’s Hosp (UK)

5:30 – 6:30 PM

Gerald D Aurbach Award LectureNovel Targets for Insulin Signaling in the Heart & VasculatureE Dale Abel, MBBS, MD, PhD, Univ of Utah Sch of Med

Causes & Consequences of Obesity: Insights from GeneticsI Sadaf Farooqi, PhD, FRCP, Univ of Cambridge Metabolic Res Lab (UK)

Plenary Sessions


P L e N A R Y S e S S I O N S

MONDAY, JUNE 25

8:00 – 9:15 AM

Roy O Greep Award LectureExploiting the Interface between Growth Factor & Progesterone Receptor Signaling in Breast Cancer ModelsCarol A Lange, PhD, Univ of Minnesota Cancer Res Ctr

miR-33: Micro-Managing Lipoprotein MetabolismKathryn J Moore, PhD, New York Univ Med Ctr

5:30 – 6:30 PM

Aging of the Female Brain: Phenotypes of Vulnerability & Targets of Opportunity to Prevent Neurodegenerative DiseaseRoberta Diaz Brinton, PhD, Univ of Southern California

Discovering a Drug: The Big PictureMichael Rosenblatt, MD, Merck & Co., Inc.

TUESDAY, JUNE 26

8:00 – 9:15 AM

Edwin B Astwood Award LectureCombinatoriality, Signal Integration, & Allostery: Determinants of Specific Transcriptional Regulation by the Glucocorticoid ReceptorKeith R Yamamoto, PhD, Univ of California-San Francisco

Cell Selective Interaction of Transcription Factors with ChromatinGordon L Hager, PhD, NIH

TUESDAY, JUNE 26

2:00 – 2:45 PM

The Sawin Lecture will be delivered by the Delbert A Fisher Research Scholar. One award recipient is selected annu-ally to support scholarly work on the history of endocrinology. The Endocrine Society thanks Dr and Mrs Delbert A Fisher for their generous support, which makes this award possible. Applica-tions for the Delbert A Fisher Research Scholar Award are solicited in the fall of the preceding year.

Nobel Prize Laureates in EndocrinologyLeonard Wartofsky, MD, Washington Hosp Ctr, Washington, DC

Since the first Nobel Prize Medals for Medicine and Physiology were awarded in 1901, a significant number of awards have been given for achieve-

ments in endocrinology or endocrine physiology. In this year’s Sawin Lecture, Dr Wartofsky will present an informative and entertaining overview of the laure-ates and the landmark accomplish-ments that have been recognized with this great honor.

Clark T Sawin Memorial History of Endocrinology Lecture


S Y M P O S I A

SATURDAY, JUNE 23

9:30 – 11:00 AM

Animal Models for PCOS

Complications of Childhood Obesity

Intersection of Reward & Metabolic Pathways

New Developments in Steroid Metabolism in Cancer

New Insights into Signaling by GPCRs

Pituitary Cells as Metabolic Sensors

Prolactin & Cancer

Thyroid Hormone & Energy Expenditure

Treatment Challenges in Osteoporosis

3:45 – 5:15 PM

Advances in Adrenal Tumors

Androgens & Prostate Cancer: 75 Years after Huggins & Hodges

BAT: Development & Therapeutic Potential

Cancer Stem Cells: Where Do We Start?

Development & Function of Hypothalamic Circuitry

Hormonal Regulation of Inflammation & Vascular Biology

Nuclear Receptors in Development & Physiology

Pediatric Implications of Reproductive Endocrine Technologies

Basic Clinical Translational

Presidential Symposia SeriesSATURDAY, JUNE 23

3:45 – 5:15 PMEndocrine Disruptors

SUNDAY, JUNE 24

9:30 –11:00 AMLeptin Revisited

3:45 – 5:15 PMNuclear Receptors in Inflammation & Immune Regulation

MONDAY, JUNE 25

9:30 – 11:00 AMImaging & Invasive Testing of the Pituitary, Parathyroid, & Adrenal Glands

3:45 – 5:15 PMTranslational Insights into Rational Selection of Second Line Therapies for Progressive Endocrine Cancer

TUESDAY, JUNE 26

3:45 – 5:15 PMDiabetes & the Brain


S Y M P O S I A

SUNDAY, JUNE 24

9:30 – 11:00 AM

B-Cell Preservation (T1 & T2)(Supported by Amylin Pharmaceuticals, Inc and Lilly USA, LLC)

‘Non-Neoplastic’ Pituitary Diseases

Notch Signaling in Skeletal Metabolism & Pathophysiology

Novel Therapeutic Approaches to Metastatic Thyroid Cancer (English)

Nuclear Receptors & Metabolic Disease

Obesity & Its Complications: Hope for the Future

Preservation of Female & Male Gonadal Functions

Steroid & Circadian Regulation of Reproductive Neuroendocrine Function

3:45 – 5:15 PM

Getting that GPCR to the Cell Surface

Long-Term Effects of GH/IGF-1 Reduction(Supported by Ipsen, US)

New Insights into Insulin Action(Supported by Lilly USA, LLC)

Non-Genomic Central Actions of Estrogens

Novel Therapeutic Approaches to Metastatic Thyroid Cancer (Spanish)

Origins & Markers of the Polycystic Ovarian Syndrome (PCOS)

Racial & Ethnic Variation in Fracture Risk: Clinical Implications

The Androgen Receptor: Eveready Battery of Prostate Cancer

Update in Endocrine Hypertension

CLiNiCAL “YeAR iN” sessiONs

SUNDAY, JUNE 24

11:15 AM – 12:00 PM

The Year in DiabetesRobert S Sherwin, MD Yale Univ Sch of Med

TUESDAY, JUNE 26

12:15 – 1:00 PM

The Year in LipidsIra J Goldberg, MD Columbia Univ

BAsiC “YeAR iN” sessiONs

MONDAY, JUNE 25

1:00 – 1:45 PM

The Year in Sex DifferencesDeborah J Clegg, PhD Univ of Texas SW Med Ctr

TUESDAY, JUNE 26

1:00 – 1:45 PM

The Year in Obesity & CancerStephen D Hursting, PhD Univ of Texas-Austin

Special Basic Science SessionSUNDAY, JUNE 24George R Brown Convention Center

1:00 – 1:45 PM

GWAS Versus Extreme PhenotypeJose Carlos Florez, MD, PHD Harvard Med Sch/Massachusetts Gen Hosp

Jonathan C Cohen, PHD Univ of Texas SW Med Ctr


MONDAY, JUNE 25

9:30 – 11:00 AM

CNS Control of Islet Function

Coregulators of Nuclear Receptors

Endocrine Regulation of Lipid & Carbohy-drate Metabolism, with Consequences for Longevity: Insights from Animal Models

New Insights in the Regulation of Puberty

New Insights into Androgen Replacement Therapy

New Mechanisms for HPA Axis Regulation

Novel Signaling Pathways during Bone Formation

State-of-the-Art Management of Nodular Thyroid Disease

3:45 – 5:15 PM

Adipose Tissue Inflammation & Remodeling

Bone Diseases in Cancer Patients

Controversial Issues in Cushing’s Syndrome: To Screen or Not To Screen? That Is the Question

Endocrine Signaling Interrupted

Male Germ Cell Development: the Good, the Bad, & the Ugly

Neuro-Modulatory Regulation of Gonadotropin Release: NKB

Putting the Brakes on Breast Cancer

Reasons for Ethnic Disparities in Diabetes(Supported by Lilly USA, LLC)

TUESDAY, JUNE 26

9:30 – 11:00 AM

Cross-Talk of Androgen Receptor with Other Signaling Pathways

CVD Risk in Diabetes: Is Glucose Important?

Gastrointestinal Neuroendocrine Tumors

Hormonal Contraceptives & Replacement Therapy in Adolescents

Hormonal Regulation of Primordial Follicle Assembly

Modulation of the IGF Axis & Cancer

New Challenges in Obesity Pathogenesis

Primary Aldosteronism: Advances in Genetics & Management

Variability in Vitamin D Assays: Implications for Research & Practice

3:45 – 5:15 PM

New Insights in the Management of Hypothyroidism

Novel Neural Mechanisms Regulating Feeding & Peripheral Metabolism

Post-Translational Modifications & Nuclear Receptor Action

Transition of Care in Adolescents with Chronic Disease

Where Is Hormone Replacement Therapy 10 Years after the WHI?

S Y M P O S I A

Basic Clinical Translational


EnDO Trivia Cup ChallengeSATURDAY, JUNE 23

6:45 – 8:30 PM

George R Brown Convention Center

Hosts: Bradley D Anawalt, MD, and Jon E Levine, PhD

This evening event allows teams of ENDO 2012 attendees to sit together at banquet rounds, enjoying appetizers and cocktails, while competing with other teams to answer light-hearted endocrine-based trivia questions via an audience response system. Prizes are given for the most creative team name and to the winning team, which also has its name en-graved on the ENDO Trivia Cup trophy. This high-profile event is quickly becoming a favorite tradition of attendees.

Reserve space for your team early, or register to be assigned to a team. Registration is on a first-come, first-served basis, until space is filled. For additional information, visit www.endo-society.org/endo2012/workshops.

Late-Breaking AbstractsThe Endocrine Society will accept late-breaking abstract submissions for ENDO 2012 from April 13 through April 27, 2012. The initiative is not a deadline extension but rather an endeavor to bring the very latest high-impact endocrine research to ENDO 2012.

Only abstracts detailing significant late-breaking results will be considered. A limited number of these abstracts will be accepted for presentation in a late-breaking oral or poster session.

Deadline for submission is April 27, 2012 at 12:59 AM ET.


Case Management ForumsCase Management Forums are designed to provide a more focused patient-oriented management discussion for clinicians attending ENDO 2012.

ADREnALn Cushing’s Disease: Dialogue between

a Surgeon & an Endocrinologist Specializing in Pituitary Disease

n Primary Hyperaldosteronism

BOnEn Endocrine Disease & Bone:

Diagnostic & Management Issues

DIABETESn Inpatient Management of Diabetes

n Reconciling Diabetes Treatment Algorithms Based on Evidence(Supported by Lilly USA, LLC)

MALE REPRODUCTIOnn Diagnosis & Management of Male

Hypogonadism in the Older Man

n Management of Apparent Secondary Hypogonadism Due to Obesity, Opiates, & Anabolic Steroids

MISCELLAnEOUSn Pitfalls & Lab-omas in Endocrine

Testing & Interpretation

PITUITARyn Management of Pediatric Thyroid

Cancer or Hyperthyroidism

n Subtle/Subclinical Hyperthyroidism

THyROIDn Management of Pediatric Thyroid

Cancer or Hyperthyroidism

n Subtle/Subclinical Hyperthyroidism

M A S T e R c L I N I c I A N S S e S S I O N S

Master Clinicians SessionsSATURDAY, JUNE 23

11:15 AM – 12:15 PM

Difficult Type 1 Diabetes Cases(Supported by Lilly USA, LLC)

Moderator: Anthony L McCall, MD, PhD, Univ of Virginia Hlth Syst

Experts: John (Jack) L Leahy, MD, Univ of Vermont Coll of Med, and Irl B Hirsch, MD, Univ of Washing-ton Med Ctr

SUNDAY, JUNE 24

11:15 AM – 12:15 PM

Diagnosis & Treatment of Peripheral Precocious PubertyModerator: Paul A Boepple, MD, Massachusetts Gen Hosp

Experts: Jean-Claude Carel, MD, Naturalia Biologia (France), and Erica A Eugster, MD, Indiana Univ Sch of Med

MONDAY, JUNE 25

12:15 PM – 1:15 PM

Difficult Pituitary CasesModerator: Laurence Katznelson, MD, Stanford Univ

Experts: Mary Lee Vance, MD, Univ of Virginia Med Ctr, and Peter J Trainer, MD, FRCP, The Christie NHS Fdn Trust (UK)

ENDO Session Library

ENDO 2012 Session Library features more than 100 lectures recorded live at ENDO.

n Session is audio synchronized with included slides

n Delivered in both online and DVD formats

n Features easily downloadable mp3 files

n Includes participating clinical and translational sessions

Now through June 3, enjoy the lowest price on the ENDO 2012 Session Library when you select the Premium Registration Package.

The Premium Package includes ENDO Registration, Session Library, and Meet-the-Professor Clinical Case Management 2012.

There’s so much great stuff happening at eNDO, it’s impossible to capture it all. Don’t worry—let the eNDO Session Library help you out.

SAve UP TO $150 Register with the

Premium Package— Get the ENDO 2012 Session Library and

So Much More

Take advantage of this special offer! www.endo-society.org/endo2012


ADREnALAdrenal Cancer

Adrenal Incidentaloma

Adrenal Insufficiency

Congenital Adrenal Hyperplasia

Pediatric Cushing Syndrome

Pheochromocytoma

BOnEChronic Kidney Disease & Bone

Glucocorticoid Osteoporosis: Which Strategies & When?

Minimally Invasive Surgery for Hyperparathyroidism

Non-PTH Hypercalcemia

Pediatric Bone Disease

Premenopausal Osteoporosis

Subtrochanteric Fractures: Role of Bisphosphonates

Tumor-Induced Osteomalacia

Update in FGF-23

Use of Bone Markers in Assessing Osteoporosis

What to Do if My Country Doesn’t Have a FRAX?

DIABETESApproach to Management of Prediabetic States (including PCOS) in a Multi-Ethnic Population

CGMS Sensors: Who Benefits, How, & When to Use?(Supported by Dexcom, Inc. and Medtronic Diabetes)

Diabetes & Pregnancy: Type 1, Gestational, Test Interpretation

Meet-the-Professor Sessions

M e e T- T H e - P R O f e S S O R

Diagnosis & Treatment of Type 2 Diabetes in Youth(Supported by Lilly USA, LLC)

Dietary Issues in Ethnic Groups

Hemoglobin A1C: Role & Pitfalls(Supported by Lilly USA, LLC)

Insulin Pumps(Supported by Lilly USA, LLC and Medtronic Diabetes))

New Information Technology (Web-based, Portable Apps)

Pediatric Type 1 Diabetes(Supported by Lilly USA, LLC)

The Very Insulin-Resistant Diabetes Patient: Work-up & Treatment(Supported by Lilly USA, LLC)

FEMALE REPRODUCTIOnAdult Turner Syndrome

Bone Health Management in Hypothalamic Amenorrhea

Contraception for Obese Women

PCOS: Use of Metformin to Allow Pregnancy; Other Treatments

Premature Ovarian Insufficiency

LIPIDS/OBESITyAssessing Readiness, Behavioral Modification, & Obesity

Lp(a) & Other CVD Risks: Worth Checking & in Whom?

Motivational Interviewing in Obese Adults

NASH/NAFLD: How to Treat & Whom to Treat?

Raising HDL: When & How? (Aim High)

Specialized Lipid Testing: When & How? What to Measure? ApoB, Particle Size?


MISCELLAnEOUSChronic Fatigue: “Tired All the Time”

Hereditary Pheochromocytoma & Paraganglioma

MEN1

PEDIATRICSChildhood Obesity: Causes

Evaluation of Premature Adrenarche

Gender Identity Disorders

Liver Disease in Childhood Obesity

Management of Gender Variant Youth

Non-Cancer Thyroid Problems in Children & Adolescents

Pediatric Calcium Disorders

Pubertal Disruption in Chronic Inflammatory Disease

PITUITARyAcromegaly(Supported by Ipsen, US)

Growth Hormone Deficiency

Hyponatremia

Radiotherapy

THyROIDDifficult Thyroid Function Tests

Management of Early Stage Cancer/ Need for RAI

Medullary Thyroid Cancer

Opthalmopathy

Role of Molecular Markers in Cancer

M e e T- T H e - P R O f e S S O R

Welcome centerFriendly ENDOExpo “experts” are here to point you in the right direction for poster or exhibitor locations.

food and BeverageCafes will be open for lunch, offering delicious options to satisfy many tastes.

Relaxation StationGet a rejuvenating massage from our onsite massage therapists.

NIH LoungeStaffed by several NIH Institutes, the Lounge offers information on various NIH programs and services.

The eNDOExpo TheaterThe ENDOExpo Theater hosts exhibitor presen-tations on products and services for endocrine physicians and scientists.

eNDO connectENDO Connect is the perfect place to meet up with colleagues, check your email, and learn about the latest advances in technology.

eNDO StoreThe ENDO Store offers a broad variety of the Society’s publications, apparel, and gifts for friends, family, and colleagues.

ENDOExpo is back! ENDOExpo 2012 features the poster presentations and informative exhibits in an easy-to-navigate layout, making your meeting experience more productive and enjoyable. Be sure to check out all the new additions to the ENDOExpo this year, including ENDO Connect, The Hormone Foundation Stage, and our new-and-improved ENDO Booth. ENDO enables you to network and collaborate, and the ENDOExpo is the heart of this experience.

Stay tuned for more information on ENDOExpo on the ENDO 2012 website. The next time you discuss your ENDO 2012 plans with colleagues, suggest meeting at the ENDOExpo!

The Hormone foundation StageThe Hormone Foundation Presents: Cooking for Pleasure, Healthy for LifeGet practical tips and guidance to improve your patients’ nutrition and wellness from featured chefs and experts. This three-day series includes moderated patient discussions addressing specific hormone-related conditions, followed by interactive cooking demonstrations of healthful recipes, and diet recommendations tailored to specific therapeutic areas.

The endocrine Society BoothGet answers to your questions about the Society, The Hormone Foundation, journals and publication products, membership, and much more.

eNDO 2013—San francisco!Visit this kiosk to get information on San Francisco, CA, the host city for ENDO 2013.

Luggage Tag KioskGet your personalized luggage tag showcasing the ENDO 2013 logo.

Meeting Announcements KioskPick up information on other endocrine-related meetings and events.

Interactive exhibit PlannerUse this convenient online planner—available on the Society’s website in early March—to search for exhibitors and plan your exhibit hall visit.


e N D O E x P O

ENDO 2012 Supporters as of January 9, 2012.

Thank You...The Endocrine Society would like to thank these companies for supporting ENDO 2012. Their support helps the Society provide a relevant and superior program for all participants.



AccReDITATION STATeMeNTThe Endocrine Society is accredited with commen-dation by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The Endocrine Society has achieved Accreditation with Commendation.

The Endocrine Society’s designates this live activity for a maximum of 33 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Oral and poster sessions at eNDO 2012 are not eligible for CMe credit.

STATeMeNT Of INDePeNDeNceAs a provider of continuing medical education (CME) accredited by the Accreditation Council for Continuing Medical Education, The Endocrine Society has a policy of ensuring that the content and quality of this educational activity are balanced, independent, objective, and scientifically rigorous. The scientific content of this activity was developed by The Endocrine Society’s Annual Meeting Steering Committee, independent of grant support and in accordance with the ACCME’s Essential Areas and Elements, including the Standards for Commercial Support. The commercial supporters of this meeting have no influence over topics or speakers. Educational grants support the production costs of the overall activity and are not used to compensate speakers in supported sessions.

DIScLAIMeRThe information presented in this activity represents the opinion of the faculty and is not necessarily the official position of The Endocrine Society.

LeARNING OBjecTIveSUpon completion of this educational activity, learn-ers will be able to:n Discuss state-of-the-art research in endocrinologyn Demonstrate updated knowledge of the

pathophysiology, diagnosis, and treatment of diabetes, obesity, cardiovascular disease, dyslipidemia, and adrenal, metabolic, bone, pediatric, pituitary, thyroid, and reproductive endocrine disorders

n Practice updated clinical skills for more effective diagnosis, management, and treatment of endo-crine disorders and related sequelae

n Apply updated knowledge and clinical skills in improving patient care

TARGeT AUDIeNceThis continuing medical education activity should be of substantial interest to endocrinologists, pediatric endocrinologists, internists, clinical researchers, and other endocrine professionals.

DIScLOSURe POLIcYThe faculty, committee members, and staff involved in planning this CME activity are required to disclose to learners any relevant financial relationship(s) that have occurred within the past 12 months with any commercial interest(s) whose products or services are discussed in the CME content. Such relationships are defined by re-muneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (e.g., stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers’ bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent faculty with relevant financial relationships from planning or delivery of content, but rather to provide learners with information that allows them to make their own judgments. It remains for learners to determine whether financial interests or relationships may influence the educational activity with regard to exposition or conclusion. The Endocrine Society has reviewed all dis-closures and resolved or managed all identified conflicts of interest, as applicable.

Faculty, committee member, and presenter disclosures will be published in the ENDO 2012 program materials.

The Endocrine Society staff associated with the development of content for this activity reported no relevant financial relationships.

POLIcY ON UNLABeLeD/Off-LABeL USeThe Endocrine Society has determined that disclosure of unlabeled/off-label or investigational use of com-mercial product(s) is informative for audiences and therefore requires this information to be disclosed to the learners at the beginning of the presentation. Uses of specific therapeutic agents, devices, and other products discussed in this educational activity may not be the same as those indicated in product labeling approved by the Food and Drug Administration (FDA). The Endocrine Society requires that any discussions of such “off-label” use be based on scientific research that conforms to generally accepted standards of experimental design, data collection, and data analysis. Before recommending or prescribing any therapeutic agent or device, learners should review the complete prescribing information, including indications, contraindications, warnings, pre-cautions, and adverse events.

PRIvAcY AND cONfIDeNTIALITY STATeMeNTThe Endocrine Society will record learners’ personal information as provided on CME evaluations to allow for issuance and tracking of CME certificates. The Endocrine Society may also track aggregate responses to questions in activities and evaluations and use these data to inform the ongoing evaluation and improvement of its CME program. No individual performance data or any other personal information collected from evaluations will be shared with third parties.

c O N T I N U I N G M e D I c A L e D U c AT I O N


Contact Information

MAIN OffIcePhone: +1.301.941.0200 (888.363.6274 toll-free in the US)

The Endocrine Society www.endo-society.org

ENDO 2012 www.endo-society.org/endo2012 The Endocrine Society8401 Connecticut Avenue, Suite 900Chevy Chase, MD 20815-5817

MeMBeRSHIPPhone: +1.301.941.0210 (888.363.6762 toll-free in the US)

Fax: 301.941.0257

Email: [email protected]

MeDIAAaron Lohr

Phone: 240.482.1380


ReGISTRATION & HOUSINGExperient

Hours: Monday through Friday, 9:00 AM – 6:00 PM ET

Phone: 866.229.2386 (toll-free) or 301.694.5243

Fax: 301.694.5124


Mail: ENDO 2012 Registrar c/o Experient PO Box 4088 Frederick, MD 21705-4088

Group Registration & Housing Fax: 847.996.5401


Mail: ENDO 2012 Group Registrar c/o Experient 568 Atrium Drive Vernon Hills, IL 60061-1731

exhibitor Registration & Housing Fax: 847.996.5401


Mail: ENDO 2012 Exhibitor Registrar c/o Experient 568 Atrium Drive Vernon Hills, IL 60061-1731

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ENDO 2012: The 94th Annual Meeting of The Endocrine Society

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