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Emergent and Urgent Dermatology, Eruptions, and Wound Care G. Scott Drew, DO, FAAD, FAOCD Smith Clinic Department of Dermatology Tucson Osteopathic Medical Foundation April 27, 2018
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Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Sep 16, 2019

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Page 1: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Emergent and Urgent Dermatology, Eruptions,

and Wound Care

G. Scott Drew, DO, FAAD, FAOCDSmith Clinic Department of DermatologyTucson Osteopathic Medical Foundation

April 27, 2018

Page 2: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Acute Cutaneous Lupus

Page 3: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Acute Cutaneous Lupus

Page 4: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Acute Cutaneous Lupus

ANA positive, Anti Ro, La Positive

Photo distributive

Need Systemic Work up

Initial tx, systemic corticosteroids, SPF

Antimalarials following negative G6PD

Page 5: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Subacute Cutaneous Lupus

Page 6: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Subacute Sutaneous Lupus Erythematosis

ANA negative, Ro and La positive

Fewer systemic symptoms

Less systemic co morbidities

Corticosteroids and steroid sparing agents, spf

Page 7: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Discoid Lupus

Page 8: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Discoid lupus

ANA, Ro and La negative

Usually not systemic

Scarring and Scaling alopecia

Photo distributed

Treatment include systemic, topical and intralesionalcorticosteroids, steroid sparing agents

Page 9: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Acral Lentiginous Melanoma

Page 10: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Acral Lentiginous Melanoma Highest morbidity and Mortality of the Melanomas

Due to delay in Diagnosis

Bob Marley’s demise

Breslow depth

Work up and wide excision based on Breslow depth

FSE monthly by patient, quarterly by physician

Excision, not biopsy

Page 11: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Congential Nevus

Page 12: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Congential (Hairy) Nevus

Very low malignant risk

High parental concern

Watch for changes

Page 13: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Bullous Pemphigoid

Page 14: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Bullous Pemphigoid Differentiate from Pemphigus, a far more serious Dx

H & E and DIF biopsy

Systemic corticosteroids

Steroid Sparing agents

Often burns out

Page 15: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Stasis dermatitis

Page 16: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Stasis dermatitis

Chronic

Circulatory Compromise

Compression Essential

Work up for Co morbidities

Prevention of Ulcerations

Page 17: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Necrotic Ulcers

Page 18: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Leg Ulcers-

-Leg ulcers are symptoms, not diagnoses

-treatment based on etiology

-biopsy if treatment not effective

-work up for co morbidities (malignancy, trauma,

diabetes, PVD, abuse, et al

Page 19: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

The magic changing ink

Page 20: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Dermatomyositis

Page 21: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Dermatomyositis Classic but subtle clinical presentation, including

Heliotrope rash, shawl sign, gottron’s papule

Work up essential: CK, Aldolase, LDH, etc

50% with associated malignancy

Biopsy confirmation

Treatment systemic corticosteroids, steroid sparing agents, spf, others

Page 22: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Pyogenic Granuloma

Etiology often trauma and microtrauma. Surgical treatment asap

Page 23: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Foreign Body Granuloma

Page 24: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Foreign Body Granuloma

History of injury important

Can be recent, usually remote

Page 25: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Erythema Multiforme Minor

Page 26: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Erythema Multiforme Minor Usually due to Drug reactions or HSV

Treatment directed at etiology

Palms, soles, mucous membranes.

Often recurrent, esp if HSV induced

Avoidance of offending drug (sulfonyl ureas, bactrim) and/or supressive anti virals

Page 27: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

EM Major/SJS

Page 28: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Molluscum contagiosum

Page 29: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Molluscum contagiosum

In toddlers, almost always associated with atopic dermatitis.

If fewer than 10, treat the AD first

If greater than 10, treat the MC

If associated with wrestling, sports, STD, treat the MC

Page 30: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Atopic dermatitis

Page 31: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Atopic Dermatitis

A lifestyle, not a tube of hydrocortisone

Increased risk of Bacterial, viral, fungal and parasitic skin infections

Associated allergy, otitis, asthma

Treatment: steroid sparing agents, emollients, mild cleaners, food, mild detergents, anti pruritics, bleach baths. Limited corticosteroids

Page 32: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 33: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 34: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 35: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Pityriasis alba

Page 36: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 37: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Cellulitis

Page 38: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Cellulits

Usually staph or strep

Community acquired vs Hospital acquired MRSA

Topical, oral, systemic antibiotics

History of prior manipulation, puncture, penetration with home sterilized safety pins, awls, needles, razors

Page 39: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Pityriasis Rosea

Page 40: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Pityriasis Rosea Herald Patch

Self limited

Pruritis variable

Rx supportive, accurate diagnosis

DDX includes parapsoriasis, guttate psoriasis, tinea, et al

Page 41: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Hidradenitis supprativa

Page 42: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Hidradenitis supprativa

Page 43: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Hidradenitis Supprativa Symptoms progressive and can be debilitating

Surgical tx as a LAST resort

TNF alfa inhibitors are first line treatment

Alternative tx include isotretinoin, rifampin, minocyline, spirinolactone, surgery

Page 44: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Basal Cell Carcinoma

Page 45: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Basal Cell Carcinoma

Most common Human Malignancy > 1,000,000/year

Rare metastasis

Surgical excision is ToC

Radiation, MOHS, ED&C, Imiquimod, vismodegib

Page 46: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

SCC

Page 47: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Squamous Cell Carcinoma Slightly higher risk of metastasis, particularly of hands,

face, scalp and neck

Surgical treatment ASAP

Clean margins

SPF

Frequent FSE

In immunocompent host, usually sun exposed

Page 48: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Squamous Cell Carcinoma

Page 49: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Squamous Cell Carcinoma

Page 50: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 51: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum
Page 52: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Systemic Malignancy Metastatic to Skin

Page 53: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Systemic Malignancy Metastatic to skin

Occasionally primary malignancy is previously unknown

Almost all systemic malignancies known to metastasize to skin

History is irregularly irregular

Page 54: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Squamous Cell Carcinoma in the immunocompromised patient

Page 55: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

SCC in Immunocompromisedpatients

Often in solid organ transplant patients, those on chemotherapy, or systemic immunosuppressants

Metastatic rate higher

Clinical presentation often more aggressive

Page 56: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Granuloma Annulare

Page 57: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Granuloma Annulare

Distinct presentations in pediatrics vs adult pts

Often confused with tinea (no scale with GA)

Can be associated with DM

Page 58: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Tinea Capitis with Kerion

Page 59: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Tinea Capitis with Kerion Epidermophyton, Microsporum and Trichophyton spp

are causative organisms

Usually associated with regional adenopathy

Tinea capitis requires oral treatment

Griseofulvin 20mg/kg x 6 weeks, terbinafine by weight

Kerion is a late sequellae.

Power of a Nickel (Powerofanickel.org) and DOcare

Page 60: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Epidermal Inclusion cyst

Topical therapy, vs ILK, vs Excision

Page 61: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Plaque Psoriasis

Page 62: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Plaque Psoriasis

Page 63: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Treatment Optionsfor BSA > 10%

Narrowband UVB

Methotrexate

Acetretin

Apremilast (PDE 4 inhibitors)

Biologics

Combinaiton theraby

Page 64: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Sebopsoriasis with Isomorphic phenoenon

Page 65: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Pediatric psoriasis

Page 66: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

One month of adalimumab

Page 67: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Compulsive excoriation

Page 68: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Compulsive Excoriation/Neurodermatitis

Rarely a primary dermatitis

Often require multidisciplinary approach

Recognition of the patients participation in the disease

Elimination of the picking/scratching/digging

Often requires psychoactive agents (doxepin, fluvoxamine, benzodiazapines)

Page 69: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Cutaneous Sarcoid

Page 70: Emergent and Urgent Dermatology, Eruptions, and Wound Caretomf.org/gd-resources/downloads/Drew2.pdf · Tinea Capitis with Kerion. Tinea Capitis with Kerion Epidermophyton, Microsporum

Diabetic foot disease